| Thursday, January 14 |
| Future Cardinal Sonny Siebert is born in St. Marys, MO. |
| Friday, January 15 |
| Future Cardinal Bob Sadowski is born in St. Louis, MO. |
| Friday, February 26 |
| Former Cardinal Ernie Lush dies in Detroit, MI at the age of 53. |
| Saturday, February 27 |
| Future Cardinal Carl Warwick is born in Dallas, TX. |
| Friday, March 19 |
| Former Cardinal Otto Williams dies in Omaha, NE at the age of 60. |
| Tuesday, April 20 |
| » Defeated Reds (0-1), 2-0 | Crosley Field (1-0) | 1-0 | |
| » Starters: Dizzy Dean vs Peaches Davis | Second | ½ out |
| » Major-league debuts: Jimmy Outlaw (Reds) |
| Thursday, April 22 |
| » Defeated Reds (0-2), 14-11 | Crosley Field (2-0) | 2-0 | Won 2 |
| » Starters: Si Johnson vs Paul Derringer | First | -- |
| Friday, April 23 |
| » Defeated Cubs (0-3), 5-4 | Sportsman's Park III (1-0) | 3-0 | Won 3 |
| » Starters: Charlie Root vs Lon Warneke | First | -- |
| » Major-league debuts: Jimmy Brown and Don Padgett (Cardinals) |
| Future Cardinal Duke Carmel is born in New York, NY. |
| Saturday, April 24 |
| » Lost to Cubs (1-3), 13-12 | Sportsman's Park III (1-1) | 3-1 | |
| » Starters: Roy Parmelee vs Ray Harrell | Third | 1 out |
| Sunday, April 25 |
| » Defeated Cubs (1-4), 4-0 | Sportsman's Park III (2-1) | 4-1 | |
| » Starters: Bill Lee vs Dizzy Dean | Second | ½ out |
| Monday, April 26 |
| » Major-league debuts: Lou Fette (Braves) |
| Tuesday, April 27 |
| » Defeated Pirates (4-1), 3-1 | Sportsman's Park III (3-1) | 5-1 | Won 2 |
| » Starters: Cy Blanton vs Bob Weiland | First | -- |
| Thursday, April 29 |
| » Defeated Reds (1-5), 6-1 | Sportsman's Park III (4-1) | 6-1 | Won 3 |
| » Starters: Peaches Davis vs Lon Warneke | First | -- |
| Friday, April 30 |
| » Defeated Reds (1-6), 7-1 | Sportsman's Park III (5-1) | 7-1 | Won 4 |
| » Starters: Gene Schott vs Dizzy Dean | First | -- |
| Saturday, May 1 |
| » Lost to Cubs (3-6), 11-4 | Wrigley Field (0-1) | 7-2 | |
| » Starters: Si Johnson vs Charlie Root | First | -- |
| » Major-league debuts: Nate Andrews (Cardinals) |
| Sunday, May 2 |
| » Lost to Cubs (4-6), 4-1 | Wrigley Field (0-2) | 7-3 | Lost 2 |
| » Starters: Bob Weiland vs Bill Lee | Second | ½ out |
| » Major-league debuts: Mickey Owen (Cardinals) |
| Tuesday, May 4 |
| » Lost to Braves (7-6), 8-1 | Braves Field (0-1) | 7-4 | Lost 3 |
| » Starters: Lon Warneke vs Lou Fette | Second | 1½ out |
| Wednesday, May 5 |
| » Defeated Braves (7-7), 13-1 | Braves Field (1-1) | 8-4 | |
| » Starters: Dizzy Dean vs Jim Turner | Second | 1½ out |
| Friday, May 7 |
| » Lost to Giants (8-6), 8-2 | Polo Grounds V (0-1) | 8-5 | |
| » Starters: Bob Weiland vs Slick Castleman | Second | 2 out |
| Saturday, May 8 |
| » Defeated Giants (8-7), 12-5 | Polo Grounds V (1-1) | 9-5 | |
| » Starters: Lon Warneke vs Hal Schumacher | Second | 1½ out |
| Future Cardinal Mike Cuellar is born in Santa Clara, Cuba. |
| Sunday, May 9 |
| » Defeated Dodgers (7-10), 7-1 | Ebbets Field (1-0) | 10-5 | Won 2 |
| » Starters: Dizzy Dean vs Max Butcher | Second | 1½ out |
| Monday, May 10 |
| » Lost to Dodgers (8-10), 8-2 | Ebbets Field (1-1) | 10-6 | |
| » Starters: Ray Harrell vs Van Mungo | Second | 2½ out |
| Future Cardinal Jim Hickman is born in Henning, TN. |
| Tuesday, May 11 |
| » Lost to Dodgers (9-10), 9-7 | Ebbets Field (1-2) | 10-7 | Lost 2 |
| » Starters: Bob Weiland vs Fred Frankhouse | Second | 3½ out |
| Wednesday, May 12 |
| » Defeated Phillies (7-12), 15-3 | Baker Bowl (1-0) | 11-7 | |
| » Starters: Bill McGee vs Claude Passeau | Second | 3½ out |
| Thursday, May 13 |
| » Defeated Phillies (7-13), 5-4 | Baker Bowl (2-0) | 12-7 | Won 2 |
| » Starters: Lon Warneke vs Hugh Mulcahy | Second | 2½ out |
| Friday, May 14 |
| » Lost to Pirates (15-4), 14-4 | Forbes Field (0-1) | 12-8 | |
| » Starters: Dizzy Dean vs Red Lucas | Second | 3½ out |
| Saturday, May 15 |
| » Defeated Pirates (15-5), 4-2 | Forbes Field (1-1) | 13-8 | |
| » Starters: Ray Harrell vs Bill Swift | Second | 2½ out |
| Sunday, May 16 |
| » Lost to Pirates (16-5), 2-1 | Forbes Field (1-2) | 13-9 | |
| » Starters: Bob Weiland vs Joe Bowman | Second | 3½ out |
| Tuesday, May 18 |
| » Defeated Giants (12-12), 4-3 | Sportsman's Park III (6-1) | 14-9 | |
| » Starters: Slick Castleman vs Lon Warneke | Second | 3½ out |
| Wednesday, May 19 |
| » Lost to Giants (13-12), 4-1 | Sportsman's Park III (6-2) | 14-10 | |
| » Starters: Carl Hubbell vs Dizzy Dean | Second | 3½ out |
| Thursday, May 20 |
| » Lost to Giants (14-12), 7-4 | Sportsman's Park III (6-3) | 14-11 | Lost 2 |
| » Starters: Harry Gumbert vs Ray Harrell | Second | 4½ out |
| Friday, May 21 |
| » Defeated Dodgers (11-14), 11-2 | Sportsman's Park III (7-3) | 15-11 | |
| » Starters: Max Butcher vs Si Johnson | Second | 3½ out |
| Saturday, May 22 |
| » Lost to Dodgers (12-14), 4-1 | Sportsman's Park III (7-4) | 15-12 | |
| » Starters: Luke Hamlin vs Jim Winford | Second | 4½ out |
| Former Cardinal Hi Jasper dies in St.Louis, MO at the age of 57. |
| Sunday, May 23 |
| » Defeated Phillies (11-18), 6-2 | Sportsman's Park III (8-4) | 16-12 | |
| » Starters: Bucky Walters vs Dizzy Dean | Second | 3½ out |
| Wednesday, May 26 |
| » Defeated Braves (12-16), 6-4 | Sportsman's Park III (9-4) | 17-12 | Won 2 |
| » Starters: Danny MacFayden vs Lon Warneke | Third | 2 out |
| Thursday, May 27 |
| » Lost to Braves (13-16), 8-7 | Sportsman's Park III (9-5) | 17-13 | |
| » Starters: Jim Turner vs Si Johnson | Third | 2½ out |
| Friday, May 28 |
| » Lost to Pirates (20-10), 10-3 | Sportsman's Park III (9-6) | 17-14 | Lost 2 |
| » Starters: Red Lucas vs Ray Harrell | Third | 3½ out |
| Saturday, May 29 |
| » Lost to Pirates (21-10), 9-4 | Sportsman's Park III (9-7) | 17-15 | Lost 3 |
| » Starters: Cy Blanton vs Dizzy Dean | Third | 3½ out |
| » Defeated Pirates (21-11), 2-1 | Sportsman's Park III (10-7) | 18-15 | |
| » Starters: Ed Brandt vs Bob Weiland | Third | 3½ out |
| Sunday, May 30 |
| » Lost to Pirates (22-11), 7-4 | Sportsman's Park III (10-8) | 18-16 | |
| » Starters: Bill Swift vs Ray Harrell | Fourth | 4½ out |
| Monday, May 31 |
| » Lost to Cubs (21-16), 4-2 | Sportsman's Park III (10-9) | 18-17 | Lost 2 |
| » Starters: Bill Lee vs Lon Warneke | Fourth | 5½ out |
| » Lost to Cubs (22-16), 6-3 | Sportsman's Park III (10-10) | 18-18 | Lost 3 |
| » Starters: Clay Bryant vs Dizzy Dean | Fourth | 5½ out |
| Wednesday, June 2 |
| » Lost to Dodgers (17-19), 6-2 | Ebbets Field (1-3) | 18-19 | Lost 4 |
| » Starters: Jim Winford vs Van Mungo | Fourth | 6½ out |
| Friday, June 4 |
| » Defeated Dodgers (17-20), 14-4 | Ebbets Field (2-3) | 19-19 | |
| » Starters: Bob Weiland vs Luke Hamlin | Fourth | 5 out |
| Saturday, June 5 |
| » Defeated Phillies (16-24), 3-1 | Baker Bowl (3-0) | 20-19 | Won 2 |
| » Starters: Dizzy Dean vs Claude Passeau | Fourth | 4 out |
| Sunday, June 6 |
| » Defeated Phillies (16-25), 7-2 | Baker Bowl (4-0) | 21-19 | Won 3 |
| » Starters: Lon Warneke vs Bucky Walters | Fourth | 4 out |
| » Phillies forfeited to Cardinals. | Baker Bowl (5-0) | 22-19 | Won 4 |
| Tuesday, June 8 |
| Future Cardinal Joe Grzenda is born in Scranton, PA. |
| Wednesday, June 9 |
| » Defeated Giants (28-18), 8-1 | Polo Grounds V (2-1) | 23-19 | Won 5 |
| » Starters: Dizzy Dean vs Carl Hubbell | Fourth | 4½ out |
| » Lost to Giants (29-18), 3-2 | Polo Grounds V (2-2) | 23-20 | |
| » Starters: Bob Weiland vs Slick Castleman | Fourth | 4½ out |
| Saturday, June 12 |
| » Defeated Braves (20-25), 4-1 | Braves Field (2-1) | 24-20 | |
| » Starters: Lon Warneke vs Danny MacFayden | Fourth | 4½ out |
| Sunday, June 13 |
| » Defeated Braves (20-26), 6-2 | Braves Field (3-1) | 25-20 | Won 2 |
| » Starters: Bob Weiland vs Jim Turner | Third | 3½ out |
| » Defeated Braves (20-27), 1-0 | Braves Field (4-1) | 26-20 | Won 3 |
| » Starters: Dizzy Dean vs Lou Fette | Third | 3½ out |
| Tuesday, June 15 |
| » Defeated Phillies (19-29), 13-4 | Sportsman's Park III (11-10) | 27-20 | Won 4 |
| » Starters: Bucky Walters vs Mike Ryba | Third | 3 out |
| Wednesday, June 16 |
| » Defeated Phillies (19-30), 7-6 | Sportsman's Park III (12-10) | 28-20 | Won 5 |
| » Starters: Claude Passeau vs Lon Warneke | Third | 2½ out |
| Thursday, June 17 |
| » Lost to Phillies (20-30), 13-7 | Sportsman's Park III (12-11) | 28-21 | |
| » Starters: Hugh Mulcahy vs Dizzy Dean | Third | 3 out |
| Friday, June 18 |
| » Defeated Braves (20-29), 5-2 | Sportsman's Park III (13-11) | 29-21 | |
| » Starters: Danny MacFayden vs Bob Weiland | Third | 3 out |
| Saturday, June 19 |
| » Defeated Braves (20-30), 7-5 | Sportsman's Park III (14-11) | 30-21 | Won 2 |
| » Starters: Lou Fette vs Mike Ryba | Third | 3 out |
| Sunday, June 20 |
| » Defeated Braves (20-31), 6-2 | Sportsman's Park III (15-11) | 31-21 | Won 3 |
| » Starters: Guy Bush vs Lon Warneke | Third | 1½ out |
| » Defeated Braves (20-32), 9-1 | Sportsman's Park III (16-11) | 32-21 | Won 4 |
| » Starters: Frank Gabler vs Dizzy Dean | Third | 1½ out |
| Tuesday, June 22 |
| » Lost to Dodgers (24-27), 2-1 | Sportsman's Park III (16-12) | 32-22 | |
| » Starters: Luke Hamlin vs Jesse Haines | Third | 2½ out |
| Wednesday, June 23 |
| » Defeated Dodgers (24-28), 3-2 | Sportsman's Park III (17-12) | 33-22 | |
| » Starters: Van Mungo vs Dizzy Dean | Third | 1½ out |
| Thursday, June 24 |
| » Defeated Dodgers (24-29), 13-3 | Sportsman's Park III (18-12) | 34-22 | Won 2 |
| » Starters: Fred Frankhouse vs Bob Weiland | Second | 1½ out |
| Friday, June 25 |
| » Defeated Giants (34-25), 9-4 | Sportsman's Park III (19-12) | 35-22 | Won 3 |
| » Starters: Slick Castleman vs Lon Warneke | Second | 1½ out |
| Saturday, June 26 |
| » Lost to Giants (35-25), 5-3 | Sportsman's Park III (19-13) | 35-23 | |
| » Starters: Cliff Melton vs Mike Ryba | Second | 1½ out |
| Sunday, June 27 |
| » Lost to Giants (36-25), 8-1 | Sportsman's Park III (19-14) | 35-24 | Lost 2 |
| » Starters: Carl Hubbell vs Dizzy Dean | Third | 1 out |
| Tuesday, June 29 |
| » Lost to Cubs (37-24), 11-9 | Sportsman's Park III (19-15) | 35-25 | Lost 3 |
| » Starters: Tex Carleton vs Bob Weiland | Third | 2 out |
| Wednesday, June 30 |
| » Lost to Cubs (38-24), 9-4 | Sportsman's Park III (19-16) | 35-26 | Lost 4 |
| » Starters: Roy Parmelee vs Lon Warneke | Third | 3 out |
| Thursday, July 1 |
| » Lost to Cubs (39-24), 6-3 | Sportsman's Park III (19-17) | 35-27 | Lost 5 |
| » Starters: Bill Lee vs Jim Winford | Fourth | 4 out |
| Saturday, July 3 |
| » Lost to Reds (25-38), 3-2 | Crosley Field (2-1) | 35-28 | Lost 6 |
| » Starters: Bob Weiland vs Paul Derringer | Third | 5½ out |
| Sunday, July 4 |
| » Defeated Reds (25-39), 1-0 | Crosley Field (3-1) | 36-28 | |
| » Starters: Dizzy Dean vs Lee Grissom | Third | 4½ out |
| » Defeated Reds (25-40), 5-2 | Crosley Field (4-1) | 37-28 | Won 2 |
| » Starters: Lon Warneke vs Peaches Davis | Third | 4½ out |
| Monday, July 5 |
| » Lost to Cubs (43-25), 13-12 | Wrigley Field (0-3) | 37-29 | |
| » Starters: Ray Harrell vs Bill Lee | Fourth | 6½ out |
| » Lost to Cubs (44-25), 9-7 | Wrigley Field (0-4) | 37-30 | Lost 2 |
| » Starters: Jim Winford vs Bill Lee | Fourth | 6½ out |
| Friday, July 9 |
| » Defeated Reds (25-43), 8-7 | Sportsman's Park III (20-17) | 38-30 | |
| » Starters: Lee Grissom vs Bob Weiland | Fourth | 5½ out |
| Saturday, July 10 |
| » Lost to Reds (26-43), 11-3 | Sportsman's Park III (20-18) | 38-31 | |
| » Starters: Paul Derringer vs Lon Warneke | Fourth | 6½ out |
| Sunday, July 11 |
| » Lost to Reds (27-43), 6-0 | Sportsman's Park III (20-19) | 38-32 | Lost 2 |
| » Starters: Peaches Davis vs Jesse Haines | Fourth | 7 out |
| » Lost to Reds (28-43), 7-0 | Sportsman's Park III (20-20) | 38-33 | Lost 3 |
| » Starters: Al Hollingsworth vs Ray Harrell | Fourth | 7 out |
| Monday, July 12 |
| » Defeated Pirates (40-32), 6-5 | Forbes Field (2-2) | 39-33 | |
| » Starters: Bob Weiland vs Jim Weaver | Fourth | 6½ out |
| Friday, July 16 |
| » Defeated Phillies (29-46), 10-3 | Baker Bowl (6-0) | 40-33 | Won 2 |
| » Starters: Si Johnson vs Bucky Walters | Fourth | 5 out |
| » Defeated Phillies (29-47), 18-10 | Baker Bowl (7-0) | 41-33 | Won 3 |
| » Starters: Jesse Haines vs Hugh Mulcahy | Fourth | 5 out |
| Saturday, July 17 |
| » Lost to Giants (48-30), 6-5 | Polo Grounds V (2-3) | 41-34 | |
| » Starters: Bob Weiland vs Slick Castleman | Fourth | 6 out |
| Sunday, July 18 |
| » Lost to Giants (49-30), 6-5 | Polo Grounds V (2-4) | 41-35 | Lost 2 |
| » Starters: Ray Harrell vs Carl Hubbell | Fourth | 8 out |
| » Lost to Giants (50-30), 11-0 | Polo Grounds V (2-5) | 41-36 | Lost 3 |
| » Starters: Lon Warneke vs Hal Schumacher | Fourth | 8 out |
| Monday, July 19 |
| » Defeated Giants (50-31), 3-2 | Polo Grounds V (3-5) | 42-36 | |
| » Starters: Si Johnson vs Harry Gumbert | Fourth | 8 out |
| Tuesday, July 20 |
| » Lost to Braves (37-44), 5-3 | Braves Field (4-2) | 42-37 | |
| » Starters: Bob Weiland vs Guy Bush | Fourth | 8½ out |
| Wednesday, July 21 |
| » Lost to Braves (38-44), 5-1 | Braves Field (4-3) | 42-38 | Lost 2 |
| » Starters: Sheriff Blake vs Lou Fette | Fourth | 10½ out |
| » Lost to Braves (39-44), 2-1 | Braves Field (4-4) | 42-39 | Lost 3 |
| » Starters: Dizzy Dean vs Johnny Lanning | Fourth | 10½ out |
| Thursday, July 22 |
| » Lost to Braves (40-44), 2-0 | Braves Field (4-5) | 42-40 | Lost 4 |
| » Starters: Si Johnson vs Danny MacFayden | Fourth | 10½ out |
| Friday, July 23 |
| » Defeated Dodgers (34-47), 4-1 | Ebbets Field (3-3) | 43-40 | |
| » Starters: Jesse Haines vs Luke Hamlin | Fourth | 10½ out |
| Saturday, July 24 |
| » Defeated Dodgers (34-48), 20-2 | Ebbets Field (4-3) | 44-40 | Won 2 |
| » Starters: Lon Warneke vs Max Butcher | Fourth | 10½ out |
| Sunday, July 25 |
| » Lost to Dodgers (35-48), 6-5 | Ebbets Field (4-4) | 44-41 | |
| » Starters: Bob Weiland vs Freddie Fitzsimmons | Fourth | 10½ out |
| » Tied Dodgers, 7-7 | Ebbets Field (4-4) | 44-41 | |
| » Starters: Dizzy Dean vs Fred Frankhouse | Fourth | 10½ out |
| Tuesday, July 27 |
| » Defeated Giants (53-35), 9-8 | Sportsman's Park III (21-20) | 45-41 | |
| » Starters: Carl Hubbell vs Si Johnson | Fourth | 10½ out |
| Wednesday, July 28 |
| » Lost to Giants (54-35), 8-4 | Sportsman's Park III (21-21) | 45-42 | |
| » Starters: Cliff Melton vs Lon Warneke | Fourth | 11½ out |
| Thursday, July 29 |
| » Defeated Giants (54-36), 5-2 | Sportsman's Park III (22-21) | 46-42 | |
| » Starters: Ben Cantwell vs Bob Weiland | Fourth | 10½ out |
| Saturday, July 31 |
| » Defeated Dodgers (36-51), 4-3 | Sportsman's Park III (23-21) | 47-42 | Won 2 |
| » Starters: Freddie Fitzsimmons vs Jesse Haines | Fourth | 11 out |
| Sunday, August 1 |
| » Lost to Dodgers (37-51), 7-3 | Sportsman's Park III (23-22) | 47-43 | |
| » Starters: Luke Hamlin vs Dizzy Dean | Fourth | 11½ out |
| » Defeated Dodgers (37-52), 7-1 | Sportsman's Park III (24-22) | 48-43 | |
| » Starters: Max Butcher vs Lon Warneke | Fourth | 11½ out |
| Tuesday, August 3 |
| » Defeated Braves (45-49), 5-2 | Sportsman's Park III (25-22) | 49-43 | Won 2 |
| » Starters: Jim Turner vs Si Johnson | Fourth | 11½ out |
| Wednesday, August 4 |
| » Defeated Braves (45-50), 7-6 | Sportsman's Park III (26-22) | 50-43 | Won 3 |
| » Starters: Lou Fette vs Bob Weiland | Fourth | 10½ out |
| Thursday, August 5 |
| » Lost to Braves (46-50), 4-1 | Sportsman's Park III (26-23) | 50-44 | |
| » Starters: Danny MacFayden vs Jesse Haines | Fourth | 10½ out |
| Friday, August 6 |
| » Defeated Phillies (40-58), 10-7 | Sportsman's Park III (27-23) | 51-44 | |
| » Starters: Claude Passeau vs Lon Warneke | Third | 11 out |
| Saturday, August 7 |
| » Defeated Phillies (40-59), 11-4 | Sportsman's Park III (28-23) | 52-44 | Won 2 |
| » Starters: Hugh Mulcahy vs Ray Harrell | Third | 10 out |
| Sunday, August 8 |
| » Defeated Phillies (40-60), 3-2 | Sportsman's Park III (29-23) | 53-44 | Won 3 |
| » Starters: Claude Passeau vs Bob Weiland | Third | 10½ out |
| » Tied Phillies, 6-6 | Sportsman's Park III (29-23) | 53-44 | |
| » Starters: Wayne LaMaster vs Dizzy Dean | Third | 10½ out |
| Monday, August 9 |
| Former Cardinal Duff Cooley dies in Dallas, TX at the age of 65. |
| Tuesday, August 10 |
| » Defeated Reds (41-56), 3-2 | Sportsman's Park III (30-23) | 54-44 | Won 4 |
| » Starters: Lee Grissom vs Lon Warneke | Third | 9½ out |
| Wednesday, August 11 |
| » Defeated Reds (41-57), 3-2 | Sportsman's Park III (31-23) | 55-44 | Won 5 |
| » Starters: Peaches Davis vs Si Johnson | Third | 9½ out |
| Friday, August 13 |
| » Defeated Pirates (53-48), 4-1 | Sportsman's Park III (32-23) | 56-44 | Won 6 |
| » Starters: Jim Weaver vs Bob Weiland | Third | 9 out |
| Saturday, August 14 |
| » Lost to Pirates (54-48), 6-5 | Sportsman's Park III (32-24) | 56-45 | |
| » Starters: Joe Bowman vs Ray Harrell | Third | 9 out |
| Sunday, August 15 |
| » Lost to Pirates (55-48), 8-4 | Sportsman's Park III (32-25) | 56-46 | Lost 2 |
| » Starters: Cy Blanton vs Lon Warneke | Third | 9 out |
| » Lost to Pirates (56-48), 4-0 | Sportsman's Park III (32-26) | 56-47 | Lost 3 |
| » Starters: Russ Bauers vs Si Johnson | Third | 9 out |
| Tuesday, August 17 |
| » Defeated Reds (44-59), 8-6 | Crosley Field (5-1) | 57-47 | |
| » Starters: Bob Weiland vs Gene Schott | Third | 8 out |
| Future Cardinal Diego Segui is born in Holguin, Cuba. |
| Thursday, August 19 |
| » Defeated Reds (44-60), 6-2 | Crosley Field (6-1) | 58-47 | Won 2 |
| » Starters: Lon Warneke vs Lee Grissom | Third | 7 out |
| » Defeated Reds (44-61), 5-1 | Crosley Field (7-1) | 59-47 | Won 3 |
| » Starters: Mike Ryba vs Peaches Davis | Third | 7 out |
| Friday, August 20 |
| » Lost to Pirates (59-49), 7-4 | Forbes Field (2-3) | 59-48 | |
| » Starters: Si Johnson vs Cy Blanton | Third | 7 out |
| Saturday, August 21 |
| » Lost to Pirates (60-49), 7-3 | Forbes Field (2-4) | 59-49 | Lost 2 |
| » Starters: Ray Harrell vs Russ Bauers | Fourth | 8 out |
| Sunday, August 22 |
| » Defeated Pirates (60-50), 12-0 | Forbes Field (3-4) | 60-49 | |
| » Starters: Bob Weiland vs Red Lucas | Third | 8 out |
| » Defeated Pirates (60-51), 9-7 | Forbes Field (4-4) | 61-49 | Won 2 |
| » Starters: Dizzy Dean vs Jim Weaver | Third | 8 out |
| Wednesday, August 25 |
| » Defeated Dodgers (44-66), 4-2 | Ebbets Field (5-4) | 62-49 | Won 3 |
| » Starters: Lon Warneke vs Waite Hoyt | Third | 6 out |
| » Defeated Dodgers (44-67), 5-2 | Ebbets Field (6-4) | 63-49 | Won 4 |
| » Starters: Si Johnson vs Van Mungo | Third | 6 out |
| Thursday, August 26 |
| » Lost to Phillies (46-66), 8-5 | Baker Bowl (7-1) | 63-50 | |
| » Starters: Dizzy Dean vs Bucky Walters | Third | 6½ out |
| » Major-league debuts: Tom Sunkel (Cardinals) |
| Friday, August 27 |
| » Lost to Phillies (47-66), 4-1 | Baker Bowl (7-2) | 63-51 | Lost 2 |
| » Starters: Bob Weiland vs Claude Passeau | Third | 7½ out |
| » Lost to Phillies (48-66), 6-3 | Baker Bowl (7-3) | 63-52 | Lost 3 |
| » Starters: Mike Ryba vs Bucky Walters | Third | 7½ out |
| Saturday, August 28 |
| » Lost to Phillies (49-66), 9-6 | Baker Bowl (7-4) | 63-53 | Lost 4 |
| » Starters: Lon Warneke vs Orville Jorgens | Third | 8 out |
| Sunday, August 29 |
| » Lost to Braves (57-61), 3-2 | Braves Field (4-6) | 63-54 | Lost 5 |
| » Starters: Si Johnson vs Jim Turner | Third | 8 out |
| » Defeated Braves (57-62), 3-0 | Braves Field (5-6) | 64-54 | |
| » Starters: Ray Harrell vs Johnny Lanning | Third | 8 out |
| Tuesday, August 31 |
| » Defeated Giants (71-47), 8-1 | Polo Grounds V (4-5) | 65-54 | Won 2 |
| » Starters: Bob Weiland vs Slick Castleman | Third | 8 out |
| Future Cardinal Tracy Stallard is born in Coeburn, VA. |
| Wednesday, September 1 |
| » Lost to Giants (72-47), 7-3 | Polo Grounds V (4-6) | 65-55 | |
| » Starters: Lon Warneke vs Hal Schumacher | Third | 8 out |
| Thursday, September 2 |
| » Lost to Giants (73-47), 5-4 | Polo Grounds V (4-7) | 65-56 | Lost 2 |
| » Starters: Si Johnson vs Harry Gumbert | Third | 9 out |
| Friday, September 3 |
| » Lost to Reds (48-70), 9-1 | Crosley Field (7-2) | 65-57 | Lost 3 |
| » Starters: Ray Harrell vs Peaches Davis | Third | 9 out |
| Sunday, September 5 |
| » Lost to Reds (49-70), 3-2 | Crosley Field (7-3) | 65-58 | Lost 4 |
| » Starters: Mike Ryba vs Gene Schott | Third | 9½ out |
| » Defeated Reds (49-71), 1-0 | Crosley Field (8-3) | 66-58 | |
| » Starters: Lon Warneke vs Al Hollingsworth | Third | 9½ out |
| Monday, September 6 |
| » Defeated Pirates (65-60), 4-1 | Sportsman's Park III (33-26) | 67-58 | Won 2 |
| » Starters: Cy Blanton vs Bob Weiland | Third | 10½ out |
| » Lost to Pirates (66-60), 5-4 | Sportsman's Park III (33-27) | 67-59 | |
| » Starters: Russ Bauers vs Si Johnson | Third | 10½ out |
| Tuesday, September 7 |
| » Lost to Cubs (75-52), 8-5 | Wrigley Field (0-5) | 67-60 | Lost 2 |
| » Starters: Sheriff Blake vs Bill Lee | Third | 11 out |
| Wednesday, September 8 |
| » Lost to Cubs (76-52), 4-0 | Wrigley Field (0-6) | 67-61 | Lost 3 |
| » Starters: Dizzy Dean vs Larry French | Fourth | 12 out |
| Thursday, September 9 |
| » Defeated Cubs (76-53), 8-2 | Wrigley Field (1-6) | 68-61 | |
| » Starters: Lon Warneke vs Charlie Root | Fourth | 11½ out |
| Friday, September 10 |
| » Lost to Cubs (77-53), 11-0 | Wrigley Field (1-7) | 68-62 | |
| » Starters: Bob Weiland vs Tex Carleton | Fourth | 11½ out |
| Saturday, September 11 |
| » Defeated Reds (50-77), 5-4 | Sportsman's Park III (34-27) | 69-62 | |
| » Starters: Paul Derringer vs Mike Ryba | Fourth | 11 out |
| Sunday, September 12 |
| » Lost to Reds (51-77), 10-7 | Sportsman's Park III (34-28) | 69-63 | |
| » Starters: Peaches Davis vs Ray Harrell | Fourth | 11 out |
| » Defeated Reds (51-78), 2-0 | Sportsman's Park III (35-28) | 70-63 | |
| » Starters: Lee Grissom vs Bob Weiland | Fourth | 11 out |
| » Major-league debuts: Howie Krist (Cardinals) |
| Tuesday, September 14 |
| » Defeated Phillies (54-78), 9-8 | Sportsman's Park III (36-28) | 71-63 | Won 2 |
| » Starters: Claude Passeau vs Si Johnson | Fourth | 10 out |
| » Defeated Phillies (54-79), 1-0 | Sportsman's Park III (37-28) | 72-63 | Won 3 |
| » Starters: Bucky Walters vs Lon Warneke | Fourth | 10 out |
| Wednesday, September 15 |
| » Tied Phillies, 6-6 | Sportsman's Park III (37-28) | 72-63 | |
| » Starters: Orville Jorgens vs Mike Ryba | Third | 10½ out |
| Future Cardinal Charley Smith is born in Charleston, SC. |
| Thursday, September 16 |
| » Defeated Phillies (54-80), 6-2 | Sportsman's Park III (38-28) | 73-63 | Won 4 |
| » Starters: Hugh Mulcahy vs Bob Weiland | Third | 10 out |
| » Defeated Phillies (54-81), 8-1 | Sportsman's Park III (39-28) | 74-63 | Won 5 |
| » Starters: Hal Kelleher vs Howie Krist | Third | 10 out |
| Friday, September 17 |
| » Defeated Braves (69-69), 2-0 | Sportsman's Park III (40-28) | 75-63 | Won 6 |
| » Starters: Lou Fette vs Si Johnson | Third | 10 out |
| Future Cardinal Orlando Cepeda is born in Ponce, P.R. |
| Saturday, September 18 |
| » Lost to Braves (70-69), 8-7 | Sportsman's Park III (40-29) | 75-64 | |
| » Starters: Danny MacFayden vs Nub Kleinke | Third | 10 out |
| Sunday, September 19 |
| » Lost to Giants (84-53), 4-3 | Sportsman's Park III (40-30) | 75-65 | Lost 2 |
| » Starters: Hal Schumacher vs Lon Warneke | Fourth | 11 out |
| Monday, September 20 |
| » Lost to Giants (85-53), 10-3 | Sportsman's Park III (40-31) | 75-66 | Lost 3 |
| » Starters: Cliff Melton vs Bob Weiland | Fourth | 12 out |
| Tuesday, September 21 |
| » Defeated Dodgers (61-81), 8-5 | Sportsman's Park III (41-31) | 76-66 | |
| » Starters: Waite Hoyt vs Howie Krist | Third | 10½ out |
| » Defeated Dodgers (61-82), 6-3 | Sportsman's Park III (42-31) | 77-66 | Won 2 |
| » Starters: Buck Marrow vs Nub Kleinke | Third | 10½ out |
| Wednesday, September 22 |
| » Defeated Dodgers (61-83), 4-2 | Sportsman's Park III (43-31) | 78-66 | Won 3 |
| » Starters: Freddie Fitzsimmons vs Si Johnson | Third | 10½ out |
| Thursday, September 23 |
| » Defeated Dodgers (61-84), 8-4 | Sportsman's Park III (44-31) | 79-66 | Won 4 |
| » Starters: Max Butcher vs Tom Sunkel | Third | 10½ out |
| Saturday, September 25 |
| » Lost to Cubs (86-59), 5-2 | Sportsman's Park III (44-32) | 79-67 | |
| » Starters: Tex Carleton vs Lon Warneke | Third | 11½ out |
| Sunday, September 26 |
| » Defeated Cubs (86-60), 6-5 | Sportsman's Park III (45-32) | 80-67 | |
| » Starters: Bill Lee vs Bob Weiland | Third | 12 out |
| » Lost to Cubs (87-60), 8-5 | Sportsman's Park III (45-33) | 80-68 | |
| » Starters: Larry French vs Howie Krist | Third | 12 out |
| Tuesday, September 28 |
| » Lost to Pirates (80-68), 6-2 | Forbes Field (4-5) | 80-69 | Lost 2 |
| » Starters: Si Johnson vs Ed Brandt | Fourth | 13½ out |
| Wednesday, September 29 |
| » Lost to Pirates (81-68), 7-5 | Forbes Field (4-6) | 80-70 | Lost 3 |
| » Starters: Lon Warneke vs Cy Blanton | Fourth | 14 out |
| Thursday, September 30 |
| » Lost to Pirates (82-68), 4-3 | Forbes Field (4-7) | 80-71 | Lost 4 |
| » Starters: Bob Weiland vs Russ Bauers | Fourth | 14½ out |
| Friday, October 1 |
| » Defeated Cubs (91-61), 4-1 | Wrigley Field (2-7) | 81-71 | |
| » Starters: Si Johnson vs Bill Lee | Fourth | 13½ out |
| Saturday, October 2 |
| » Lost to Cubs (92-61), 5-1 | Wrigley Field (2-8) | 81-72 | |
| » Starters: Bob Weiland vs Curt Davis | Fourth | 14½ out |
| Sunday, October 3 |
| » Lost to Cubs (93-61), 6-4 | Wrigley Field (2-9) | 81-73 | Lost 2 |
| » Starters: Howie Krist vs Clay Bryant | Fourth | 15½ out |
| » Major-league debuts: Kirby Higbe (Cubs) |
| Monday, October 18 |
| Former Cardinal Charlie Starr dies in Pasadena, CA at the age of 60. |
| Monday, November 1 |
| Former Cardinal Benny Frey dies in Spring Arbor Township, MI at the age of 32. |
| Monday, December 13 |
| Future Cardinal Ron Taylor is born in Toronto, ON. |
