| Friday, February 12 |
| Future Athletic Stan Johnson is born in Dallas, TX. |
| Sunday, March 21 |
| Future Athletic Dave Thies is born in Minneapolis, MN. |
| Monday, April 19 |
| » Defeated Senators (0-1), 4-3 | Griffith Stadium (1-0) | 1-0 | |
| » Starters: Eddie Smith vs Joe Cascarella | First | -- |
| Tuesday, April 20 |
| » Lost to Red Sox (1-0), 11-5 | Shibe Park (0-1) | 1-1 | |
| » Starters: Wes Ferrell vs Harry Kelley | Third | ½ out |
| » Major-league debuts: Bobby Doerr (Red Sox) |
| Friday, April 23 |
| » Defeated Senators (1-2), 7-1 | Griffith Stadium (2-0) | 2-1 | |
| » Starters: George Caster vs Pete Appleton | Third | ½ out |
| Saturday, April 24 |
| » Defeated Senators (1-3), 6-4 | Griffith Stadium (3-0) | 3-1 | Won 2 |
| » Starters: Al Williams vs Bobo Newsom | Second | 1 out |
| Monday, April 26 |
| » Lost to Yankees (3-1), 7-1 | Yankee Stadium (0-1) | 3-2 | |
| » Starters: Harry Kelley vs Johnny Broaca | Third | ½ out |
| Friday, April 30 |
| » Lost to Red Sox (3-2), 15-5 | Fenway Park (0-1) | 3-3 | Lost 2 |
| » Starters: Bud Thomas vs Wes Ferrell | Fifth | 1½ out |
| Saturday, May 1 |
| » Defeated Senators (2-7), 2-1 | Shibe Park (1-1) | 4-3 | |
| » Starters: Pete Appleton vs George Caster | Third | 1½ out |
| Sunday, May 2 |
| » Lost to Senators (3-7), 10-7 | Shibe Park (1-2) | 4-4 | |
| » Starters: Jimmie DeShong vs Al Williams | Fourth | 2 out |
| Wednesday, May 5 |
| » Defeated White Sox (3-7), 7-6 | Comiskey Park I (1-0) | 5-4 | |
| » Starters: Lynn Nelson vs Monty Stratton | Fourth | 2 out |
| Thursday, May 6 |
| » Defeated White Sox (3-8), 3-1 | Comiskey Park I (2-0) | 6-4 | Won 2 |
| » Starters: Bud Thomas vs Johnny Rigney | Third | 1 out |
| Friday, May 7 |
| » Lost to Browns (4-7), 9-6 | Sportsman's Park III (0-1) | 6-5 | |
| » Starters: George Caster vs Jim Walkup | Fourth | 1½ out |
| Saturday, May 8 |
| » Defeated Browns (4-8), 5-1 | Sportsman's Park III (1-1) | 7-5 | |
| » Starters: Harry Kelley vs Oral Hildebrand | Third | 1 out |
| Sunday, May 9 |
| » Defeated Tigers (9-6), 9-8 | Tiger Stadium (1-0) | 8-5 | Won 2 |
| » Starters: Al Williams vs Elden Auker | First | -- |
| Monday, May 10 |
| » Defeated Tigers (9-7), 9-5 | Tiger Stadium (2-0) | 9-5 | Won 3 |
| » Starters: Bud Thomas vs Tommy Bridges | First | -- |
| Tuesday, May 11 |
| » Defeated Tigers (9-8), 4-1 | Tiger Stadium (3-0) | 10-5 | Won 4 |
| » Starters: George Caster vs Roxie Lawson | First | -- |
| Saturday, May 15 |
| » Lost to Yankees (11-8), 6-5 | Shibe Park (1-3) | 10-6 | |
| » Starters: Monte Pearson vs Harry Kelley | First | -- |
| Sunday, May 16 |
| » Lost to Yankees (12-8), 8-4 | Shibe Park (1-4) | 10-7 | Lost 2 |
| » Starters: Red Ruffing vs George Caster | Second | 1½ out |
| Monday, May 17 |
| » Defeated Yankees (12-9), 3-2 | Shibe Park (2-4) | 11-7 | |
| » Starters: Lefty Gomez vs Bud Thomas | First | -- |
| Tuesday, May 18 |
| » Defeated Tigers (11-11), 8-7 | Shibe Park (3-4) | 12-7 | Won 2 |
| » Starters: George Gill vs Harry Kelley | First | -- |
| Wednesday, May 19 |
| » Lost to Tigers (12-11), 9-0 | Shibe Park (3-5) | 12-8 | |
| » Starters: Tommy Bridges vs Bud Thomas | First | -- |
| Thursday, May 20 |
| » Lost to Tigers (13-11), 3-2 | Shibe Park (3-6) | 12-9 | Lost 2 |
| » Starters: Roxie Lawson vs Eddie Smith | Second | 1 out |
| Friday, May 21 |
| » Defeated White Sox (10-13), 4-3 | Shibe Park (4-6) | 13-9 | |
| » Starters: Monty Stratton vs George Caster | Second | 1 out |
| Saturday, May 22 |
| » Defeated White Sox (10-14), 10-9 | Shibe Park (5-6) | 14-9 | Won 2 |
| » Starters: Vern Kennedy vs Lynn Nelson | First | -- |
| Sunday, May 23 |
| » Defeated Browns (8-17), 6-2 | Shibe Park (6-6) | 15-9 | Won 3 |
| » Starters: Oral Hildebrand vs Harry Kelley | First | -- |
| Monday, May 24 |
| » Lost to Browns (9-17), 8-6 | Shibe Park (6-7) | 15-10 | |
| » Starters: Tommy Thomas vs Lynn Nelson | Second | 1 out |
| Tuesday, May 25 |
| » Lost to Indians (13-11), 4-2 | Shibe Park (6-8) | 15-11 | Lost 2 |
| » Starters: Mel Harder vs Eddie Smith | Second | 2 out |
| Wednesday, May 26 |
| » Lost to Indians (14-11), 8-6 | Shibe Park (6-9) | 15-12 | Lost 3 |
| » Starters: Johnny Allen vs Harry Kelley | Third | 3 out |
| Thursday, May 27 |
| » Lost to Indians (15-11), 8-7 | Shibe Park (6-10) | 15-13 | Lost 4 |
| » Starters: Earl Whitehill vs George Caster | Fourth | 3 out |
| Saturday, May 29 |
| » Lost to Yankees (20-11), 9-4 | Yankee Stadium (0-2) | 15-14 | Lost 5 |
| » Starters: Buck Ross vs Red Ruffing | Fifth | 5 out |
| » Lost to Yankees (21-11), 10-3 | Yankee Stadium (0-3) | 15-15 | Lost 6 |
| » Starters: Eddie Smith vs Spud Chandler | Fifth | 5 out |
| Sunday, May 30 |
| » Lost to Yankees (22-11), 13-1 | Yankee Stadium (0-4) | 15-16 | Lost 7 |
| » Starters: Harry Kelley vs Lefty Gomez | Sixth | 6 out |
| Monday, May 31 |
| » Lost to Senators (16-20), 6-3 | Griffith Stadium (3-1) | 15-17 | Lost 8 |
| » Starters: George Caster vs Carl Fischer | Seventh | 7 out |
| » Lost to Senators (17-20), 6-1 | Griffith Stadium (3-2) | 15-18 | Lost 9 |
| » Starters: Lynn Nelson vs Monte Weaver | Seventh | 7 out |
| Friday, June 4 |
| » Lost to Browns (11-25), 7-6 | Sportsman's Park III (1-2) | 15-19 | Lost 10 |
| » Starters: Buck Ross vs Oral Hildebrand | Sixth | 6½ out |
| » Defeated Browns (11-26), 4-3 | Sportsman's Park III (2-2) | 16-19 | |
| » Starters: Harry Kelley vs Jack Knott | Sixth | 6½ out |
| » Major-league debuts: Wayne Ambler (Athletics) |
| Saturday, June 5 |
| » Lost to White Sox (21-17), 2-0 | Comiskey Park I (2-1) | 16-20 | |
| » Starters: George Caster vs John Whitehead | Sixth | 7½ out |
| Sunday, June 6 |
| » Lost to White Sox (22-17), 6-1 | Comiskey Park I (2-2) | 16-21 | Lost 2 |
| » Starters: Bud Thomas vs Ted Lyons | Seventh | 8 out |
| » Lost to White Sox (23-17), 6-5 | Comiskey Park I (2-3) | 16-22 | Lost 3 |
| » Starters: Eddie Smith vs Monty Stratton | Seventh | 8 out |
| Monday, June 7 |
| » Lost to White Sox (24-17), 12-6 | Comiskey Park I (2-4) | 16-23 | Lost 4 |
| » Starters: George Turbeville vs Bill Dietrich | Seventh | 8 out |
| Tuesday, June 8 |
| » Lost to Tigers (25-20), 6-0 | Tiger Stadium (3-1) | 16-24 | Lost 5 |
| » Starters: Harry Kelley vs Elden Auker | Sixth | 8 out |
| Thursday, June 10 |
| » Lost to Tigers (26-20), 4-3 | Tiger Stadium (3-2) | 16-25 | Lost 6 |
| » Starters: George Caster vs Tommy Bridges | Seventh | 9 out |
| Friday, June 11 |
| » Defeated Indians (24-18), 11-3 | League Park II (1-0) | 17-25 | |
| » Starters: Buck Ross vs Willis Hudlin | Seventh | 9 out |
| Saturday, June 12 |
| » Defeated Indians (24-19), 3-2 | League Park II (2-0) | 18-25 | Won 2 |
| » Starters: Harry Kelley vs Denny Galehouse | Seventh | 8 out |
| Sunday, June 13 |
| » Lost to Indians (25-19), 2-1 | Cleveland Stadium (0-1) | 18-26 | |
| » Starters: Bud Thomas vs Johnny Allen | Seventh | 9½ out |
| » Lost to Indians (26-19), 2-0 | Cleveland Stadium (0-2) | 18-27 | Lost 2 |
| » Starters: Eddie Smith vs Earl Whitehill | Seventh | 9½ out |
| Tuesday, June 15 |
| » Lost to Browns (16-30), 5-1 | Shibe Park (6-11) | 18-28 | Lost 3 |
| » Starters: Chief Hogsett vs George Caster | Seventh | 10½ out |
| Wednesday, June 16 |
| » Lost to Browns (17-30), 3-2 | Shibe Park (6-12) | 18-29 | Lost 4 |
| » Starters: Jack Knott vs Harry Kelley | Seventh | 11½ out |
| Friday, June 18 |
| Former Athletic Willie Adams dies in Albany, NY at the age of 47. |
| Saturday, June 19 |
| » Lost to Tigers (31-22), 8-6 | Shibe Park (6-13) | 18-30 | Lost 5 |
| » Starters: Roxie Lawson vs Buck Ross | Seventh | 12 out |
| Sunday, June 20 |
| » Lost to Tigers (32-22), 6-3 | Shibe Park (6-14) | 18-31 | Lost 6 |
| » Starters: Elden Auker vs George Caster | Seventh | 14 out |
| » Lost to Tigers (33-22), 8-1 | Shibe Park (6-15) | 18-32 | Lost 7 |
| » Starters: Tommy Bridges vs Harry Kelley | Seventh | 14 out |
| Tuesday, June 22 |
| » Lost to White Sox (30-25), 2-0 | Shibe Park (6-16) | 18-33 | Lost 8 |
| » Starters: Monty Stratton vs Buck Ross | Seventh | 15 out |
| Wednesday, June 23 |
| » Lost to White Sox (31-25), 2-0 | Shibe Park (6-17) | 18-34 | Lost 9 |
| » Starters: Bill Dietrich vs Bud Thomas | Eighth | 15 out |
| Thursday, June 24 |
| » Lost to White Sox (32-25), 7-2 | Shibe Park (6-18) | 18-35 | Lost 10 |
| » Starters: Thornton Lee vs Harry Kelley | Eighth | 16 out |
| Saturday, June 26 |
| » Defeated Indians (27-28), 7-0 | Shibe Park (7-18) | 19-35 | |
| » Starters: Mel Harder vs Buck Ross | Seventh | 15½ out |
| Sunday, June 27 |
| » Defeated Indians (27-29), 10-0 | Shibe Park (8-18) | 20-35 | Won 2 |
| » Starters: Denny Galehouse vs George Caster | Seventh | 16 out |
| » Lost to Indians (28-29), 7-2 | Shibe Park (8-19) | 20-36 | |
| » Starters: Willis Hudlin vs Harry Kelley | Seventh | 16 out |
| Tuesday, June 29 |
| » Lost to Yankees (38-21), 3-2 | Shibe Park (8-20) | 20-37 | Lost 2 |
| » Starters: Spud Chandler vs Eddie Smith | Seventh | 17 out |
| Wednesday, June 30 |
| » Lost to Yankees (39-21), 5-1 | Shibe Park (8-21) | 20-38 | Lost 3 |
| » Starters: Lefty Gomez vs Bud Thomas | Seventh | 18 out |
| Thursday, July 1 |
| » Lost to Yankees (40-21), 12-7 | Shibe Park (8-22) | 20-39 | Lost 4 |
| » Starters: Red Ruffing vs Buck Ross | Seventh | 19 out |
| Friday, July 2 |
| » Lost to Red Sox (32-26), 8-4 | Fenway Park (0-2) | 20-40 | Lost 5 |
| » Starters: George Caster vs Johnny Marcum | Eighth | 19 out |
| Saturday, July 3 |
| » Lost to Red Sox (33-26), 8-3 | Fenway Park (0-3) | 20-41 | Lost 6 |
| » Starters: Harry Kelley vs Fritz Ostermueller | Eighth | 20 out |
| Sunday, July 4 |
| » Lost to Red Sox (34-26), 7-6 | Fenway Park (0-4) | 20-42 | Lost 7 |
| » Starters: Herman Fink vs Lefty Grove | Eighth | 21½ out |
| » Lost to Red Sox (35-26), 4-2 | Fenway Park (0-5) | 20-43 | Lost 8 |
| » Starters: Bud Thomas vs Bobo Newsom | Eighth | 21½ out |
| Monday, July 5 |
| » Lost to Senators (30-35), 5-3 | Shibe Park (8-23) | 20-44 | Lost 9 |
| » Starters: Jimmie DeShong vs George Caster | Eighth | 23 out |
| » Tied Senators, 2-2 | Shibe Park (8-23) | 20-44 | |
| » Starters: Ed Linke vs Eddie Smith | Eighth | 23 out |
| Friday, July 9 |
| » Lost to Red Sox (36-28), 12-11 | Shibe Park (8-24) | 20-45 | Lost 10 |
| » Starters: Bobo Newsom vs George Turbeville | Eighth | 24 out |
| Saturday, July 10 |
| » Lost to Red Sox (37-28), 9-2 | Shibe Park (8-25) | 20-46 | Lost 11 |
| » Starters: Lefty Grove vs George Caster | Eighth | 25½ out |
| » Lost to Red Sox (38-28), 5-2 | Shibe Park (8-26) | 20-47 | Lost 12 |
| » Starters: Johnny Marcum vs Herman Fink | Eighth | 25½ out |
| Sunday, July 11 |
| » Lost to Red Sox (39-28), 9-4 | Shibe Park (8-27) | 20-48 | Lost 13 |
| » Starters: Jack Wilson vs Bud Thomas | Eighth | 27 out |
| » Lost to Red Sox (40-28), 8-2 | Shibe Park (8-28) | 20-49 | Lost 14 |
| » Starters: Archie McKain vs Eddie Smith | Eighth | 27 out |
| Wednesday, July 14 |
| » Lost to White Sox (44-31), 6-4 | Comiskey Park I (2-5) | 20-50 | Lost 15 |
| » Starters: Buck Ross vs Vern Kennedy | Eighth | 28 out |
| Thursday, July 15 |
| » Defeated White Sox (44-32), 2-1 | Comiskey Park I (3-5) | 21-50 | |
| » Starters: George Caster vs Bill Dietrich | Eighth | 28 out |
| Friday, July 16 |
| » Lost to White Sox (45-32), 9-4 | Comiskey Park I (3-6) | 21-51 | |
| » Starters: Bud Thomas vs Sugar Cain | Eighth | 28 out |
| Saturday, July 17 |
| » Lost to Browns (24-49), 10-2 | Sportsman's Park III (2-3) | 21-52 | Lost 2 |
| » Starters: George Turbeville vs Lou Koupal | Eighth | 29 out |
| Sunday, July 18 |
| » Lost to Browns (25-49), 10-6 | Sportsman's Park III (2-4) | 21-53 | Lost 3 |
| » Starters: Harry Kelley vs Jim Walkup | Eighth | 29½ out |
| » Defeated Browns (25-50), 7-6 | Sportsman's Park III (3-4) | 22-53 | |
| » Starters: Buck Ross vs Julio Bonetti | Eighth | 29½ out |
| Tuesday, July 20 |
| » Defeated Indians (37-38), 7-5 | League Park II (3-0) | 23-53 | Won 2 |
| » Starters: George Caster vs Earl Whitehill | Eighth | 30½ out |
| Wednesday, July 21 |
| » Lost to Indians (38-38), 9-8 | League Park II (3-1) | 23-54 | |
| » Starters: Bud Thomas vs Mel Harder | Eighth | 32 out |
| » Lost to Indians (39-38), 8-7 | League Park II (3-2) | 23-55 | Lost 2 |
| » Starters: Buck Ross vs Denny Galehouse | Eighth | 32 out |
| Thursday, July 22 |
| » Lost to Indians (40-38), 5-1 | League Park II (3-3) | 23-56 | Lost 3 |
| » Starters: Eddie Smith vs Whit Wyatt | Eighth | 32 out |
| Friday, July 23 |
| » Defeated Tigers (48-33), 16-4 | Tiger Stadium (4-2) | 24-56 | |
| » Starters: Harry Kelley vs Elden Auker | Eighth | 31½ out |
| » Lost to Tigers (49-33), 9-8 | Tiger Stadium (4-3) | 24-57 | |
| » Starters: Herman Fink vs Roxie Lawson | Eighth | 31½ out |
| Sunday, July 25 |
| » Lost to Tigers (50-33), 12-9 | Tiger Stadium (4-4) | 24-58 | Lost 2 |
| » Starters: George Caster vs Boots Poffenberger | Eighth | 31½ out |
| Tuesday, July 27 |
| » Defeated Indians (41-41), 4-3 | Shibe Park (9-28) | 25-58 | |
| » Starters: Mel Harder vs George Caster | Eighth | 31½ out |
| Wednesday, July 28 |
| » Defeated Indians (41-42), 11-7 | Shibe Park (10-28) | 26-58 | Won 2 |
| » Starters: Whit Wyatt vs Buck Ross | Eighth | 30½ out |
| Thursday, July 29 |
| » Lost to Indians (42-42), 5-4 | Shibe Park (10-29) | 26-59 | |
| » Starters: Denny Galehouse vs Eddie Smith | Eighth | 31½ out |
| Saturday, July 31 |
| » Lost to White Sox (55-36), 2-0 | Shibe Park (10-30) | 26-60 | Lost 2 |
| » Starters: Monty Stratton vs Harry Kelley | Eighth | 32 out |
| Sunday, August 1 |
| » Lost to White Sox (56-36), 4-3 | Shibe Park (10-31) | 26-61 | Lost 3 |
| » Starters: Ted Lyons vs George Caster | Eighth | 33½ out |
| » Lost to White Sox (57-36), 5-3 | Shibe Park (10-32) | 26-62 | Lost 4 |
| » Starters: Bill Dietrich vs Buck Ross | Eighth | 33½ out |
| Tuesday, August 3 |
| » Defeated Tigers (51-39), 2-1 | Shibe Park (11-32) | 27-62 | |
| » Starters: Tommy Bridges vs Bud Thomas | Eighth | 34 out |
| Wednesday, August 4 |
| » Lost to Tigers (52-39), 11-7 | Shibe Park (11-33) | 27-63 | |
| » Starters: Slick Coffman vs Harry Kelley | Eighth | 35 out |
| Thursday, August 5 |
| » Lost to Tigers (53-39), 5-3 | Shibe Park (11-34) | 27-64 | Lost 2 |
| » Starters: Elden Auker vs Eddie Smith | Eighth | 36 out |
| Saturday, August 7 |
| » Lost to Browns (32-62), 4-1 | Shibe Park (11-35) | 27-65 | Lost 3 |
| » Starters: Jack Knott vs George Caster | Eighth | 37½ out |
| Sunday, August 8 |
| » Defeated Browns (32-63), 5-4 | Shibe Park (12-35) | 28-65 | |
| » Starters: Oral Hildebrand vs Buck Ross | Eighth | 37 out |
| » Defeated Browns (32-64), 7-3 | Shibe Park (13-35) | 29-65 | Won 2 |
| » Starters: Bill Trotter vs Bud Thomas | Eighth | 37 out |
| Tuesday, August 10 |
| » Lost to Senators (42-53), 15-7 | Griffith Stadium (3-3) | 29-66 | |
| » Starters: George Caster vs Monte Weaver | Eighth | 38 out |
| » Lost to Senators (43-53), 8-6 | Griffith Stadium (3-4) | 29-67 | Lost 2 |
| » Starters: Eddie Smith vs Pete Appleton | Eighth | 38 out |
| Wednesday, August 11 |
| » Lost to Senators (44-53), 5-4 | Griffith Stadium (3-5) | 29-68 | Lost 3 |
| » Starters: Bud Thomas vs Wes Ferrell | Eighth | 39½ out |
| Thursday, August 12 |
| » Lost to Senators (45-53), 5-4 | Griffith Stadium (3-6) | 29-69 | Lost 4 |
| » Starters: Harry Kelley vs Jimmie DeShong | Eighth | 40 out |
| Friday, August 13 |
| » Defeated Yankees (70-31), 4-3 | Shibe Park (14-35) | 30-69 | |
| » Starters: Lefty Gomez vs Buck Ross | Seventh | 39 out |
| Saturday, August 14 |
| » Defeated Yankees (70-32), 12-6 | Shibe Park (15-35) | 31-69 | Won 2 |
| » Starters: Kemp Wicker vs Bud Thomas | Eighth | 38 out |
| Future Athletic Joe Horlen is born in San Antonio, TX. |
| Sunday, August 15 |
| » Defeated Yankees (70-33), 5-4 | Shibe Park (16-35) | 32-69 | Won 3 |
| » Starters: Red Ruffing vs Eddie Smith | Eighth | 37 out |
| Tuesday, August 17 |
| » Lost to Red Sox (59-45), 6-1 | Shibe Park (16-36) | 32-70 | |
| » Starters: Jack Wilson vs Buck Ross | Eighth | 38½ out |
| Future Athletic Diego Segui is born in Holguin, Cuba. Future Athletic Diego Segui is born in Holguin, Cuba. |
| Wednesday, August 18 |
| » Defeated Red Sox (59-46), 4-2 | Shibe Park (17-36) | 33-70 | |
| » Starters: Bobo Newsom vs George Caster | Eighth | 38½ out |
| Thursday, August 19 |
| » Lost to Red Sox (60-46), 5-4 | Shibe Park (17-37) | 33-71 | |
| » Starters: Johnny Marcum vs Harry Kelley | Eighth | 39½ out |
| Friday, August 20 |
| » Lost to Yankees (75-33), 8-7 | Yankee Stadium (0-5) | 33-72 | Lost 2 |
| » Starters: Buck Ross vs Ivy Andrews | Eighth | 40½ out |
| Saturday, August 21 |
| » Defeated Yankees (75-34), 5-2 | Yankee Stadium (1-5) | 34-72 | |
| » Starters: Eddie Smith vs Monte Pearson | Eighth | 39½ out |
| Sunday, August 22 |
| » Lost to Yankees (76-34), 4-1 | Yankee Stadium (1-6) | 34-73 | |
| » Starters: Bud Thomas vs Lefty Gomez | Seventh | 40½ out |
| Tuesday, August 24 |
| » Lost to Tigers (66-45), 6-3 | Tiger Stadium (4-5) | 34-74 | Lost 2 |
| » Starters: Harry Kelley vs Tommy Bridges | Seventh | 40 out |
| » Defeated Tigers (66-46), 9-8 | Tiger Stadium (5-5) | 35-74 | |
| » Starters: George Caster vs Boots Poffenberger | Seventh | 40 out |
| Wednesday, August 25 |
| » Lost to Tigers (67-46), 10-4 | Tiger Stadium (5-6) | 35-75 | |
| » Starters: George Caster vs Elden Auker | Seventh | 41 out |
| Thursday, August 26 |
| » Lost to Indians (55-56), 10-5 | League Park II (3-4) | 35-76 | Lost 2 |
| » Starters: Eddie Smith vs Mel Harder | Seventh | 42 out |
| Friday, August 27 |
| » Lost to Indians (56-56), 5-3 | League Park II (3-5) | 35-77 | Lost 3 |
| » Starters: Buck Ross vs Denny Galehouse | Seventh | 43 out |
| Saturday, August 28 |
| » Lost to Indians (57-56), 5-4 | League Park II (3-6) | 35-78 | Lost 4 |
| » Starters: Bud Thomas vs Earl Whitehill | Eighth | 43 out |
| Sunday, August 29 |
| » Defeated White Sox (67-53), 16-0 | Comiskey Park I (4-6) | 36-78 | |
| » Starters: George Caster vs Monty Stratton | Eighth | 43½ out |
| » Lost to White Sox (68-53), 5-3 | Comiskey Park I (4-7) | 36-79 | |
| » Starters: Harry Kelley vs John Whitehead | Eighth | 43½ out |
| Tuesday, August 31 |
| » Lost to Browns (38-80), 2-1 | Sportsman's Park III (3-5) | 36-80 | Lost 2 |
| » Starters: Bud Thomas vs Chief Hogsett | Eighth | 43½ out |
| » Defeated Browns (38-81), 7-3 | Sportsman's Park III (4-5) | 37-80 | |
| » Starters: Eddie Smith vs Lou Koupal | Eighth | 43½ out |
| Wednesday, September 1 |
| » Defeated Browns (38-82), 5-2 | Sportsman's Park III (5-5) | 38-80 | Won 2 |
| » Starters: Al Williams vs Oral Hildebrand | Seventh | 42½ out |
| Thursday, September 2 |
| » Defeated Browns (38-83), 5-3 | Sportsman's Park III (6-5) | 39-80 | Won 3 |
| » Starters: Harry Kelley vs Jim Walkup | Seventh | 41½ out |
| » Major-league debuts: Red Barkley (Browns) |
| Friday, September 3 |
| » Major-league debuts: Jimmy Wasdell (Senators) |
| Saturday, September 4 |
| » Lost to Red Sox (66-54), 5-4 | Fenway Park (0-6) | 39-81 | |
| » Manager: Earle Mack |
| » Starters: George Caster vs Bobo Newsom | Seventh | 41½ out |
| » Defeated Red Sox (66-55), 10-4 | Fenway Park (1-6) | 40-81 | |
| » Starters: Bud Thomas vs Jack Wilson | Seventh | 41½ out |
| Monday, September 6 |
| » Lost to Yankees (84-40), 6-3 | Shibe Park (17-38) | 40-82 | |
| » Starters: Bump Hadley vs Buck Ross | Seventh | 44 out |
| » Lost to Yankees (85-40), 2-1 | Shibe Park (17-39) | 40-83 | Lost 2 |
| » Starters: Ivy Andrews vs Eddie Smith | Seventh | 44 out |
| Wednesday, September 8 |
| » Defeated Senators (59-67), 2-0 | Shibe Park (18-39) | 41-83 | |
| » Starters: Ken Chase vs George Caster | Sixth | 45 out |
| » Lost to Senators (60-67), 1-0 | Shibe Park (18-40) | 41-84 | |
| » Starters: Pete Appleton vs Bud Thomas | Sixth | 45 out |
| » Major-league debuts: George Case (Senators) |
| Thursday, September 9 |
| » Lost to Senators (61-67), 13-6 | Shibe Park (18-41) | 41-85 | Lost 2 |
| » Starters: Dick Lanahan vs Harry Kelley | Seventh | 45½ out |
| » Lost to Senators (62-67), 12-10 | Shibe Park (18-42) | 41-86 | Lost 3 |
| » Starters: Ed Linke vs Al Williams | Seventh | 45½ out |
| » Major-league debuts: Joe Krakauskas (Senators) |
| Friday, September 10 |
| » Defeated Senators (62-68), 5-3 | Shibe Park (19-42) | 42-86 | |
| » Starters: Wes Ferrell vs Buck Ross | Seventh | 44½ out |
| Saturday, September 11 |
| » Lost to Red Sox (70-60), 6-4 | Shibe Park (19-43) | 42-87 | |
| » Starters: Bobo Newsom vs Eddie Smith | Seventh | 45½ out |
| Sunday, September 12 |
| » Lost to Red Sox (71-60), 13-6 | Shibe Park (19-44) | 42-88 | Lost 2 |
| » Starters: Jack Wilson vs George Caster | Seventh | 46 out |
| Tuesday, September 14 |
| » Lost to Browns (40-94), 11-4 | Shibe Park (19-45) | 42-89 | Lost 3 |
| » Starters: Lou Koupal vs Bud Thomas | Seventh | 47 out |
| Wednesday, September 15 |
| » Defeated Browns (40-95), 8-2 | Shibe Park (20-45) | 43-89 | |
| » Starters: Jim Walkup vs Al Williams | Seventh | 47 out |
| » Lost to Browns (41-95), 3-1 | Shibe Park (20-46) | 43-90 | |
| » Starters: Bill Trotter vs Eddie Smith | Seventh | 47 out |
| Thursday, September 16 |
| » Defeated Browns (41-96), 4-3 | Shibe Park (21-46) | 44-90 | |
| » Starters: Jack Knott vs Harry Kelley | Seventh | 47 out |
| Friday, September 17 |
| Future Athletic Orlando Cepeda is born in Ponce, P.R. |
| Saturday, September 18 |
| » Lost to Tigers (82-55), 5-2 | Shibe Park (21-47) | 44-91 | |
| » Starters: Tommy Bridges vs Buck Ross | Seventh | 48 out |
| » Defeated Tigers (82-56), 5-4 | Shibe Park (22-47) | 45-91 | |
| » Starters: Roxie Lawson vs Bud Thomas | Seventh | 48 out |
| Sunday, September 19 |
| » Defeated Indians (74-66), 8-4 | Shibe Park (23-47) | 46-91 | Won 2 |
| » Starters: Bob Feller vs Chubby Dean | Seventh | 46½ out |
| » Defeated Indians (74-67), 5-3 | Shibe Park (24-47) | 47-91 | Won 3 |
| » Starters: Denny Galehouse vs George Caster | Seventh | 46½ out |
| Tuesday, September 21 |
| » Defeated White Sox (78-63), 5-4 | Shibe Park (25-47) | 48-91 | Won 4 |
| » Starters: Bill Cox vs Al Williams | Seventh | 46½ out |
| Wednesday, September 22 |
| » Lost to White Sox (79-63), 9-3 | Shibe Park (25-48) | 48-92 | |
| » Starters: Thornton Lee vs Harry Kelley | Seventh | 48 out |
| Thursday, September 23 |
| » Lost to White Sox (80-63), 1-0 | Shibe Park (25-49) | 48-93 | Lost 2 |
| » Starters: John Whitehead vs Buck Ross | Seventh | 48 out |
| Saturday, September 25 |
| » Lost to Senators (70-74), 5-3 | Griffith Stadium (3-7) | 48-94 | Lost 3 |
| » Starters: Eddie Smith vs Bill Phebus | Seventh | 49½ out |
| Sunday, September 26 |
| » Tied Senators, 7-7 | Griffith Stadium (3-7) | 48-94 | |
| » Starters: Al Williams vs Joe Kohlman | Seventh | 49 out |
| Monday, September 27 |
| » Lost to Red Sox (76-68), 6-2 | Fenway Park (1-7) | 48-95 | Lost 4 |
| » Starters: George Caster vs Bobo Newsom | Seventh | 49 out |
| » Defeated Red Sox (76-69), 6-0 | Fenway Park (2-7) | 49-95 | |
| » Starters: Bud Thomas vs Bobo Newsom | Seventh | 49 out |
| Wednesday, September 29 |
| » Lost to Yankees (101-48), 15-4 | Yankee Stadium (1-7) | 49-96 | |
| » Starters: George Caster vs Kemp Wicker | Seventh | 49 out |
| » Defeated Yankees (101-49), 3-0 | Yankee Stadium (2-7) | 50-96 | |
| » Starters: Eddie Smith vs Ivy Andrews | Seventh | 49 out |
| Thursday, September 30 |
| » Defeated Yankees (101-50), 8-3 | Yankee Stadium (3-7) | 51-96 | Won 2 |
| » Starters: Harry Kelley vs Bump Hadley | Seventh | 47 out |
| » Defeated Yankees (101-51), 6-3 | Yankee Stadium (4-7) | 52-96 | Won 3 |
| » Starters: Buck Ross vs Frank Makosky | Seventh | 47 out |
| Saturday, October 2 |
| » Defeated Senators (72-79), 10-3 | Shibe Park (26-49) | 53-96 | Won 4 |
| » Starters: Ken Chase vs Bill Kalfass | Seventh | 46½ out |
| » Tied Senators, 6-6 | Shibe Park (26-49) | 53-96 | |
| » Starters: Monte Weaver vs Randy Gumpert | Seventh | 46½ out |
| Sunday, October 3 |
| » Defeated Senators (72-80), 5-4 | Shibe Park (27-49) | 54-96 | Won 5 |
| » Starters: Jimmie DeShong vs Bud Thomas | Seventh | 47 out |
| » Lost to Senators (73-80), 4-3 | Shibe Park (27-50) | 54-97 | |
| » Starters: Joe Kohlman vs Eddie Smith | Seventh | 47 out |
| Monday, October 18 |
| Former Athletic Charlie Starr dies in Pasadena, CA at the age of 60. |
Game information provided by Retrosheet (www.retrosheet.org) |