| Tuesday, January 8 |
| Future Tiger Reno Bertoia is born in St. Vito Udine, Italy. |
| Thursday, January 17 |
| Future Tiger Dick Brown is born in Shinnston, WV. |
| Sunday, February 3 |
| Future Tiger Dick Tracewski is born in Eynon, PA. |
| Monday, February 11 |
| Future Tiger George Alusik is born in Ashley, PA. |
| Tuesday, April 16 |
| » Major-league debuts: Beau Bell (Browns) |
| Wednesday, April 17 |
| » Lost to White Sox (1-0), 7-6 | Tiger Stadium (0-1) | 0-1 | |
| » Starters: Sad Sam Jones vs Schoolboy Rowe | Third | 1½ out |
| Thursday, April 18 |
| » Defeated White Sox (1-1), 5-4 | Tiger Stadium (1-1) | 1-1 | |
| » Starters: Les Tietje vs Tommy Bridges | Fourth | 1 out |
| Friday, April 19 |
| » Lost to White Sox (2-1), 3-2 | Tiger Stadium (1-2) | 1-2 | |
| » Starters: John Whitehead vs Firpo Marberry | Fourth | 1 out |
| » Major-league debuts: John Whitehead (White Sox) |
| Future Tiger John Wyatt is born in Chicago, IL. |
| Saturday, April 20 |
| » Lost to Indians (2-0), 2-1 | Tiger Stadium (1-3) | 1-3 | Lost 2 |
| » Starters: Oral Hildebrand vs Elden Auker | Sixth | 2 out |
| » Major-league debuts: Joe Sullivan (Tigers) |
| Sunday, April 21 |
| » Defeated Indians (2-1), 3-2 | Tiger Stadium (2-3) | 2-3 | |
| » Starters: Monte Pearson vs Carl Fischer | Sixth | 2 out |
| Monday, April 22 |
| » Lost to Indians (3-1), 5-0 | Tiger Stadium (2-4) | 2-4 | |
| » Starters: Willis Hudlin vs Tommy Bridges | Sixth | 3 out |
| Tuesday, April 23 |
| » Lost to White Sox (4-3), 7-2 | Comiskey Park I (0-1) | 2-5 | Lost 2 |
| » Starters: General Crowder vs Sad Sam Jones | Seventh | 4 out |
| Wednesday, April 24 |
| » Lost to White Sox (5-3), 10-4 | Comiskey Park I (0-2) | 2-6 | Lost 3 |
| » Starters: Firpo Marberry vs John Whitehead | Seventh | 4½ out |
| Thursday, April 25 |
| » Lost to White Sox (6-3), 9-8 | Comiskey Park I (0-3) | 2-7 | Lost 4 |
| » Starters: Schoolboy Rowe vs Vern Kennedy | Seventh | 5 out |
| Friday, April 26 |
| » Lost to Indians (7-1), 11-3 | League Park II (0-1) | 2-8 | Lost 5 |
| » Starters: Elden Auker vs Willis Hudlin | Seventh | 6 out |
| Saturday, April 27 |
| » Lost to Indians (8-1), 9-2 | League Park II (0-2) | 2-9 | Lost 6 |
| » Starters: Tommy Bridges vs Mel Harder | Sixth | 7 out |
| Sunday, April 28 |
| » Defeated Indians (8-2), 5-3 | League Park II (1-2) | 3-9 | |
| » Starters: Joe Sullivan vs Oral Hildebrand | Fifth | 6 out |
| Monday, April 29 |
| » Defeated Browns (2-9), 18-0 | Sportsman's Park III (1-0) | 4-9 | Won 2 |
| » Starters: Tommy Bridges vs Bobo Newsom | Fifth | 5½ out |
| Tuesday, April 30 |
| » Defeated Browns (2-10), 11-3 | Sportsman's Park III (2-0) | 5-9 | Won 3 |
| » Starters: General Crowder vs Fay Thomas | Sixth | 5 out |
| Saturday, May 4 |
| » Defeated Red Sox (8-6), 5-2 | Tiger Stadium (3-4) | 6-9 | Won 4 |
| » Starters: Wes Ferrell vs Joe Sullivan | Sixth | 4½ out |
| Tuesday, May 7 |
| » Defeated Athletics (3-12), 5-3 | Tiger Stadium (4-4) | 7-9 | Won 5 |
| » Starters: Sugar Cain vs Tommy Bridges | Fifth | 5 out |
| Wednesday, May 8 |
| » Lost to Athletics (4-12), 7-6 | Tiger Stadium (4-5) | 7-10 | |
| » Starters: Roy Mahaffey vs Schoolboy Rowe | Fifth | 6 out |
| Friday, May 10 |
| » Defeated Senators (10-9), 8-4 | Tiger Stadium (5-5) | 8-10 | |
| » Starters: Bump Hadley vs Joe Sullivan | Sixth | 4 out |
| Saturday, May 11 |
| » Lost to Senators (11-9), 10-7 | Tiger Stadium (5-6) | 8-11 | |
| » Starters: Bobby Burke vs Clyde Hatter | Fifth | 5½ out |
| Monday, May 13 |
| » Defeated Yankees (11-9), 3-0 | Tiger Stadium (6-6) | 9-11 | |
| » Starters: Lefty Gomez vs Schoolboy Rowe | Fifth | 5 out |
| Tuesday, May 14 |
| » Defeated Yankees (11-10), 10-4 | Tiger Stadium (7-6) | 10-11 | Won 2 |
| » Starters: Johnny Broaca vs General Crowder | Fifth | 4½ out |
| Wednesday, May 15 |
| » Lost to Yankees (12-10), 4-0 | Tiger Stadium (7-7) | 10-12 | |
| » Starters: Red Ruffing vs Joe Sullivan | Sixth | 5½ out |
| Thursday, May 16 |
| » Defeated Senators (11-12), 7-2 | Griffith Stadium (1-0) | 11-12 | |
| » Starters: Tommy Bridges vs Bump Hadley | Fifth | 5 out |
| Friday, May 17 |
| » Lost to Senators (12-12), 10-8 | Griffith Stadium (1-1) | 11-13 | |
| » Starters: Schoolboy Rowe vs Ed Linke | Sixth | 5 out |
| Saturday, May 18 |
| » Defeated Senators (12-13), 6-4 | Griffith Stadium (2-1) | 12-13 | |
| » Starters: General Crowder vs Earl Whitehill | Fifth | 5 out |
| Sunday, May 19 |
| » Defeated Senators (12-14), 16-6 | Griffith Stadium (3-1) | 13-13 | Won 2 |
| » Starters: Joe Sullivan vs Bobby Burke | Fifth | 5 out |
| Monday, May 20 |
| » Defeated Athletics (8-16), 8-6 | Shibe Park (1-0) | 14-13 | Won 3 |
| » Starters: Tommy Bridges vs Bill Dietrich | Fifth | 4 out |
| Wednesday, May 22 |
| » Defeated Athletics (8-17), 4-1 | Shibe Park (2-0) | 15-13 | Won 4 |
| » Starters: Elden Auker vs George Blaeholder | Fifth | 3½ out |
| Thursday, May 23 |
| » Defeated Red Sox (15-13), 5-3 | Fenway Park (1-0) | 16-13 | Won 5 |
| » Starters: Schoolboy Rowe vs Gordon Rhodes | Fourth | 3 out |
| Friday, May 24 |
| » Lost to Red Sox (16-13), 8-4 | Fenway Park (1-1) | 16-14 | |
| » Starters: General Crowder vs Lefty Grove | Fifth | 3 out |
| Saturday, May 25 |
| » Defeated Red Sox (16-14), 3-2 | Fenway Park (2-1) | 17-14 | |
| » Starters: Tommy Bridges vs Fritz Ostermueller | Fourth | 3 out |
| Sunday, May 26 |
| » Lost to Yankees (20-13), 2-0 | Yankee Stadium (0-1) | 17-15 | |
| » Starters: Joe Sullivan vs Vito Tamulis | Fifth | 4 out |
| Monday, May 27 |
| » Lost to Yankees (21-13), 3-1 | Yankee Stadium (0-2) | 17-16 | Lost 2 |
| » Starters: Schoolboy Rowe vs Johnny Allen | Fifth | 4 out |
| Tuesday, May 28 |
| » Defeated Yankees (21-14), 8-3 | Yankee Stadium (1-2) | 18-16 | |
| » Starters: General Crowder vs Lefty Gomez | Fourth | 3 out |
| Former Tiger Charlie Sullivan dies in Maiden, NC at the age of 33. |
| Thursday, May 30 |
| » Lost to Browns (9-22), 10-7 | Tiger Stadium (7-8) | 18-17 | |
| » Starters: Sugar Cain vs Elden Auker | Fourth | 4 out |
| » Defeated Browns (9-23), 2-0 | Tiger Stadium (8-8) | 19-17 | |
| » Starters: Russ Van Atta vs Tommy Bridges | Fourth | 4 out |
| Future Tiger Ed Rakow is born in Pittsburgh, PA. |
| Friday, May 31 |
| » Defeated Browns (9-24), 6-5 | Tiger Stadium (9-8) | 20-17 | Won 2 |
| » Starters: Bob Weiland vs Joe Sullivan | Fourth | 3½ out |
| Saturday, June 1 |
| » Lost to White Sox (22-14), 5-4 | Tiger Stadium (9-9) | 20-18 | |
| » Starters: Ted Lyons vs Schoolboy Rowe | Fourth | 4 out |
| Sunday, June 2 |
| » Defeated White Sox (22-15), 10-5 | Tiger Stadium (10-9) | 21-18 | |
| » Starters: Whit Wyatt vs General Crowder | Fourth | 4 out |
| Wednesday, June 5 |
| » Defeated Indians (23-17), 5-4 | Tiger Stadium (11-9) | 22-18 | Won 2 |
| » Starters: Willis Hudlin vs Tommy Bridges | Fourth | 3½ out |
| » Tied Indians, 4-4 | Tiger Stadium (11-9) | 22-18 | |
| » Starters: Clint Brown vs Joe Sullivan | Fourth | 3½ out |
| Thursday, June 6 |
| » Defeated Indians (23-18), 10-9 | Tiger Stadium (12-9) | 23-18 | Won 3 |
| » Starters: Lefty Stewart vs Schoolboy Rowe | Third | 3 out |
| Friday, June 7 |
| » Lost to White Sox (23-17), 9-8 | Comiskey Park I (0-4) | 23-19 | |
| » Starters: General Crowder vs Ted Lyons | Fourth | 3 out |
| Saturday, June 8 |
| » Lost to White Sox (24-17), 3-2 | Comiskey Park I (0-5) | 23-20 | Lost 2 |
| » Starters: Elden Auker vs Vern Kennedy | Fourth | 3½ out |
| Sunday, June 9 |
| » Defeated White Sox (24-18), 4-1 | Comiskey Park I (1-5) | 24-20 | |
| » Starters: Tommy Bridges vs John Whitehead | Fourth | 3 out |
| Tuesday, June 11 |
| » Lost to Red Sox (24-22), 3-1 | Tiger Stadium (12-10) | 24-21 | |
| » Starters: Lefty Grove vs Joe Sullivan | Fifth | 5 out |
| » Lost to Red Sox (25-22), 5-2 | Tiger Stadium (12-11) | 24-22 | Lost 2 |
| » Starters: Wes Ferrell vs General Crowder | Fifth | 5 out |
| Wednesday, June 12 |
| » Defeated Red Sox (25-23), 4-1 | Tiger Stadium (13-11) | 25-22 | |
| » Starters: Johnny Welch vs Schoolboy Rowe | Third | 4½ out |
| Thursday, June 13 |
| » Defeated Red Sox (25-24), 6-1 | Tiger Stadium (14-11) | 26-22 | Won 2 |
| » Starters: Gordon Rhodes vs Tommy Bridges | Third | 4½ out |
| Friday, June 14 |
| » Lost to Red Sox (26-24), 10-8 | Tiger Stadium (14-12) | 26-23 | |
| » Starters: George Hockette vs Clyde Hatter | Third | 5½ out |
| Saturday, June 15 |
| » Defeated Athletics (21-27), 10-1 | Tiger Stadium (15-12) | 27-23 | |
| » Starters: George Blaeholder vs Elden Auker | Third | 5 out |
| » Defeated Athletics (21-28), 11-3 | Tiger Stadium (16-12) | 28-23 | Won 2 |
| » Starters: Johnny Marcum vs General Crowder | Third | 5 out |
| Sunday, June 16 |
| » Defeated Athletics (21-29), 13-3 | Tiger Stadium (17-12) | 29-23 | Won 3 |
| » Starters: Al Benton vs Schoolboy Rowe | Third | 4½ out |
| Wednesday, June 19 |
| » Lost to Yankees (35-19), 13-3 | Tiger Stadium (17-13) | 29-24 | |
| » Starters: Lefty Gomez vs General Crowder | Fourth | 6½ out |
| » Lost to Yankees (36-19), 7-6 | Tiger Stadium (17-14) | 29-25 | Lost 2 |
| » Starters: Vito Tamulis vs Tommy Bridges | Fourth | 6½ out |
| Thursday, June 20 |
| » Lost to Yankees (37-19), 5-2 | Tiger Stadium (17-15) | 29-26 | Lost 3 |
| » Starters: Johnny Allen vs Joe Sullivan | Fourth | 7½ out |
| Friday, June 21 |
| » Defeated Yankees (37-20), 7-0 | Tiger Stadium (18-15) | 30-26 | |
| » Starters: Red Ruffing vs Schoolboy Rowe | Fourth | 6½ out |
| Saturday, June 22 |
| » Defeated Senators (26-31), 7-0 | Tiger Stadium (19-15) | 31-26 | Won 2 |
| » Starters: Bobby Burke vs General Crowder | Fourth | 5 out |
| » Defeated Senators (26-32), 10-9 | Tiger Stadium (20-15) | 32-26 | Won 3 |
| » Starters: Ed Linke vs Elden Auker | Fourth | 5 out |
| Sunday, June 23 |
| » Lost to Senators (27-32), 12-7 | Tiger Stadium (20-16) | 32-27 | |
| » Starters: Bump Hadley vs Joe Sullivan | Fourth | 5 out |
| Monday, June 24 |
| » Defeated Senators (27-33), 9-8 | Tiger Stadium (21-16) | 33-27 | |
| » Starters: Earl Whitehill vs Tommy Bridges | Fourth | 5 out |
| Tuesday, June 25 |
| » Lost to Senators (28-33), 7-4 | Tiger Stadium (21-17) | 33-28 | |
| » Starters: Leon Pettit vs Schoolboy Rowe | Fourth | 5 out |
| Future Tiger Don Demeter is born in Oklahoma City, OK. |
| Thursday, June 27 |
| » Defeated White Sox (31-25), 9-5 | Comiskey Park I (2-5) | 34-28 | |
| » Starters: General Crowder vs Vern Kennedy | Fourth | 5 out |
| Friday, June 28 |
| » Defeated Browns (18-40), 10-1 | Sportsman's Park III (3-0) | 35-28 | Won 2 |
| » Starters: Elden Auker vs Sugar Cain | Third | 4 out |
| » Defeated Browns (18-41), 7-2 | Sportsman's Park III (4-0) | 36-28 | Won 3 |
| » Starters: Vic Sorrell vs Russ Van Atta | Third | 4 out |
| Saturday, June 29 |
| » Lost to Browns (19-41), 9-3 | Sportsman's Park III (4-1) | 36-29 | |
| » Starters: Tommy Bridges vs Ivy Andrews | Third | 5 out |
| Sunday, June 30 |
| » Defeated Browns (19-42), 18-1 | Sportsman's Park III (5-1) | 37-29 | |
| » Starters: Schoolboy Rowe vs Fay Thomas | Third | 3½ out |
| » Defeated Browns (19-43), 11-6 | Sportsman's Park III (6-1) | 38-29 | Won 2 |
| » Starters: General Crowder vs Jack Knott | Third | 3½ out |
| Monday, July 1 |
| » Defeated Indians (37-27), 4-1 | Tiger Stadium (22-17) | 39-29 | Won 3 |
| » Starters: Thornton Lee vs Elden Auker | Third | 3 out |
| Tuesday, July 2 |
| » Defeated Indians (37-28), 8-3 | Tiger Stadium (23-17) | 40-29 | Won 4 |
| » Starters: Lefty Stewart vs Tommy Bridges | Second | 3 out |
| Wednesday, July 3 |
| » Defeated Indians (37-29), 11-7 | Tiger Stadium (24-17) | 41-29 | Won 5 |
| » Starters: Oral Hildebrand vs Vic Sorrell | Second | 3 out |
| Thursday, July 4 |
| » Defeated Indians (37-30), 6-5 | League Park II (2-2) | 42-29 | Won 6 |
| » Starters: General Crowder vs Mel Harder | Second | 2 out |
| » Defeated Indians (37-31), 10-4 | League Park II (3-2) | 43-29 | Won 7 |
| » Starters: Schoolboy Rowe vs Willis Hudlin | Second | 2 out |
| Friday, July 5 |
| » Defeated Browns (19-48), 16-1 | Tiger Stadium (25-17) | 44-29 | Won 8 |
| » Starters: Russ Van Atta vs Vic Sorrell | Second | 2½ out |
| Saturday, July 6 |
| » Defeated Browns (19-49), 7-6 | Tiger Stadium (26-17) | 45-29 | Won 9 |
| » Starters: Sugar Cain vs Tommy Bridges | Second | 2 out |
| Sunday, July 7 |
| » Defeated Browns (19-50), 12-5 | Tiger Stadium (27-17) | 46-29 | Won 10 |
| » Starters: Fay Thomas vs Elden Auker | Second | 2 out |
| Wednesday, July 10 |
| » Lost to Senators (31-42), 12-11 | Griffith Stadium (3-2) | 46-30 | |
| » Starters: Tommy Bridges vs Earl Whitehill | Second | 2½ out |
| Thursday, July 11 |
| » Defeated Senators (31-43), 7-6 | Griffith Stadium (4-2) | 47-30 | |
| » Starters: Schoolboy Rowe vs Bump Hadley | Second | 2½ out |
| Friday, July 12 |
| » Defeated Senators (31-44), 2-1 | Griffith Stadium (5-2) | 48-30 | Won 2 |
| » Starters: General Crowder vs Ed Linke | Second | 2½ out |
| Saturday, July 13 |
| » Lost to Athletics (32-41), 18-5 | Shibe Park (2-1) | 48-31 | |
| » Starters: Elden Auker vs Johnny Marcum | Second | 3 out |
| » Defeated Athletics (32-42), 6-3 | Shibe Park (3-1) | 49-31 | |
| » Starters: Tommy Bridges vs Roy Mahaffey | Second | 3 out |
| Sunday, July 14 |
| » Lost to Athletics (33-42), 4-3 | Shibe Park (3-2) | 49-32 | |
| » Starters: Schoolboy Rowe vs Bill Dietrich | Second | 2½ out |
| Monday, July 15 |
| Future Tiger Bob Miller is born in Berwyn, IL. |
| Tuesday, July 16 |
| » Lost to Athletics (34-42), 8-2 | Shibe Park (3-3) | 49-33 | Lost 2 |
| » Starters: General Crowder vs George Blaeholder | Second | 2½ out |
| Thursday, July 18 |
| » Defeated Red Sox (43-39), 8-0 | Fenway Park (3-1) | 50-33 | |
| » Starters: Schoolboy Rowe vs Wes Ferrell | Second | 2½ out |
| Friday, July 19 |
| » Defeated Red Sox (43-40), 9-7 | Fenway Park (4-1) | 51-33 | Won 2 |
| » Starters: Tommy Bridges vs Fritz Ostermueller | Second | 2½ out |
| Saturday, July 20 |
| » Defeated Red Sox (43-41), 6-5 | Fenway Park (5-1) | 52-33 | Won 3 |
| » Starters: General Crowder vs Gordon Rhodes | Second | 3 out |
| Sunday, July 21 |
| » Lost to Red Sox (44-41), 7-6 | Fenway Park (5-2) | 52-34 | |
| » Starters: Tommy Bridges vs Lefty Grove | Second | 2½ out |
| Tuesday, July 23 |
| » Lost to Yankees (51-31), 7-5 | Yankee Stadium (1-3) | 52-35 | Lost 2 |
| » Starters: Schoolboy Rowe vs Johnny Allen | Second | 2½ out |
| » Defeated Yankees (51-32), 3-1 | Yankee Stadium (2-3) | 53-35 | |
| » Starters: Vic Sorrell vs Lefty Gomez | Second | 2½ out |
| Wednesday, July 24 |
| » Defeated Yankees (51-33), 4-0 | Yankee Stadium (3-3) | 54-35 | Won 2 |
| » Starters: General Crowder vs Red Ruffing | First | -- |
| Thursday, July 25 |
| Future Tiger Larry Sherry is born in Los Angeles, CA. |
| Friday, July 26 |
| » Defeated Indians (44-41), 8-2 | League Park II (4-2) | 55-35 | Won 3 |
| » Starters: Elden Auker vs Thornton Lee | First | -- |
| Saturday, July 27 |
| » Defeated Indians (44-42), 6-2 | League Park II (5-2) | 56-35 | Won 4 |
| » Starters: Tommy Bridges vs Mel Harder | First | -- |
| Sunday, July 28 |
| » Defeated Indians (44-43), 14-6 | League Park II (6-2) | 57-35 | Won 5 |
| » Starters: Schoolboy Rowe vs Lefty Stewart | First | -- |
| Monday, July 29 |
| » Lost to Indians (45-43), 6-5 | League Park II (6-3) | 57-36 | |
| » Starters: General Crowder vs Willis Hudlin | First | -- |
| Tuesday, July 30 |
| » Lost to Browns (30-60), 8-6 | Tiger Stadium (27-18) | 57-37 | Lost 2 |
| » Starters: Russ Van Atta vs Schoolboy Rowe | First | -- |
| Wednesday, July 31 |
| » Defeated Browns (30-61), 9-3 | Tiger Stadium (28-18) | 58-37 | |
| » Starters: Ivy Andrews vs Tommy Bridges | First | -- |
| Future Tiger Terry Fox is born in Chicago, IL. |
| Thursday, August 1 |
| » Defeated Browns (30-62), 6-3 | Tiger Stadium (29-18) | 59-37 | Won 2 |
| » Starters: Russ Van Atta vs General Crowder | First | -- |
| Saturday, August 3 |
| » Defeated Indians (46-46), 5-4 | Tiger Stadium (30-18) | 60-37 | Won 3 |
| » Starters: Willis Hudlin vs Elden Auker | First | -- |
| » Defeated Indians (46-47), 7-3 | Tiger Stadium (31-18) | 61-37 | Won 4 |
| » Starters: Monte Pearson vs Schoolboy Rowe | First | -- |
| Sunday, August 4 |
| » Defeated Indians (46-48), 7-0 | Tiger Stadium (32-18) | 62-37 | Won 5 |
| » Starters: Mel Harder vs Tommy Bridges | First | -- |
| Thursday, August 8 |
| » Defeated White Sox (52-44), 5-2 | Tiger Stadium (33-18) | 63-37 | Won 6 |
| » Starters: John Whitehead vs General Crowder | First | -- |
| Friday, August 9 |
| » Defeated White Sox (52-45), 4-3 | Tiger Stadium (34-18) | 64-37 | Won 7 |
| » Starters: Ted Lyons vs Schoolboy Rowe | First | -- |
| Saturday, August 10 |
| » Defeated White Sox (52-46), 4-0 | Tiger Stadium (35-18) | 65-37 | Won 8 |
| » Starters: Les Tietje vs Tommy Bridges | First | -- |
| Sunday, August 11 |
| » Defeated White Sox (52-47), 4-1 | Tiger Stadium (36-18) | 66-37 | Won 9 |
| » Starters: Vern Kennedy vs Elden Auker | First | -- |
| Tuesday, August 13 |
| » Lost to Senators (45-59), 4-3 | Tiger Stadium (36-19) | 66-38 | |
| » Starters: Earl Whitehill vs General Crowder | First | -- |
| Wednesday, August 14 |
| » Defeated Senators (45-60), 18-2 | Tiger Stadium (37-19) | 67-38 | |
| » Starters: Bobo Newsom vs Schoolboy Rowe | First | -- |
| Thursday, August 15 |
| » Defeated Senators (45-61), 6-3 | Tiger Stadium (38-19) | 68-38 | Won 2 |
| » Starters: Ed Linke vs Tommy Bridges | First | -- |
| Friday, August 16 |
| » Lost to Senators (46-61), 8-1 | Tiger Stadium (38-20) | 68-39 | |
| » Starters: Bump Hadley vs Elden Auker | First | -- |
| Saturday, August 17 |
| » Defeated Yankees (61-45), 3-2 | Tiger Stadium (39-20) | 69-39 | |
| » Starters: Lefty Gomez vs General Crowder | First | -- |
| Sunday, August 18 |
| » Defeated Yankees (61-46), 6-0 | Tiger Stadium (40-20) | 70-39 | Won 2 |
| » Starters: Red Ruffing vs Schoolboy Rowe | First | -- |
| Future Tiger Bob Humphreys is born in Covington, VA. |
| Monday, August 19 |
| » Lost to Yankees (62-46), 7-5 | Tiger Stadium (40-21) | 70-40 | |
| » Starters: Johnny Broaca vs Vic Sorrell | First | -- |
| Tuesday, August 20 |
| » Lost to Yankees (63-46), 6-5 | Tiger Stadium (40-22) | 70-41 | Lost 2 |
| » Starters: Johnny Allen vs Schoolboy Rowe | First | -- |
| Wednesday, August 21 |
| » Defeated Red Sox (59-55), 4-1 | Tiger Stadium (41-22) | 71-41 | |
| » Starters: Fritz Ostermueller vs General Crowder | First | -- |
| » Defeated Red Sox (59-56), 3-2 | Tiger Stadium (42-22) | 72-41 | Won 2 |
| » Starters: Johnny Welch vs Elden Auker | First | -- |
| Thursday, August 22 |
| » Lost to Red Sox (60-56), 10-9 | Tiger Stadium (42-23) | 72-42 | |
| » Starters: Rube Walberg vs Tommy Bridges | First | -- |
| Friday, August 23 |
| » Defeated Red Sox (60-57), 6-0 | Tiger Stadium (43-23) | 73-42 | |
| » Starters: Gordon Rhodes vs Schoolboy Rowe | First | -- |
| Saturday, August 24 |
| » Defeated Red Sox (60-58), 2-0 | Tiger Stadium (44-23) | 74-42 | Won 2 |
| » Starters: Lefty Grove vs Roxie Lawson | First | -- |
| Sunday, August 25 |
| » Defeated Athletics (50-63), 6-3 | Tiger Stadium (45-23) | 75-42 | Won 3 |
| » Starters: Johnny Marcum vs Elden Auker | First | -- |
| Monday, August 26 |
| » Defeated Athletics (50-64), 13-7 | Tiger Stadium (46-23) | 76-42 | Won 4 |
| » Starters: Bill Dietrich vs General Crowder | First | -- |
| » Lost to Athletics (51-64), 3-2 | Tiger Stadium (46-24) | 76-43 | |
| » Starters: George Blaeholder vs Tommy Bridges | First | -- |
| Tuesday, August 27 |
| » Defeated Athletics (51-65), 6-5 | Tiger Stadium (47-24) | 77-43 | |
| » Starters: Carl Doyle vs Vic Sorrell | First | -- |
| » Defeated Athletics (51-66), 5-0 | Tiger Stadium (48-24) | 78-43 | Won 2 |
| » Starters: George Turbeville vs Schoolboy Rowe | First | -- |
| Wednesday, August 28 |
| » Defeated Athletics (51-67), 11-0 | Tiger Stadium (49-24) | 79-43 | Won 3 |
| » Starters: Wedo Martini vs Roxie Lawson | First | -- |
| Thursday, August 29 |
| » Defeated Browns (48-74), 13-3 | Sportsman's Park III (7-1) | 80-43 | Won 4 |
| » Starters: Elden Auker vs Jim Walkup | First | -- |
| Friday, August 30 |
| » Lost to Browns (49-74), 8-7 | Sportsman's Park III (7-2) | 80-44 | |
| » Starters: Tommy Bridges vs Sugar Cain | First | -- |
| Saturday, August 31 |
| » Defeated Browns (49-75), 5-1 | Sportsman's Park III (8-2) | 81-44 | |
| » Starters: General Crowder vs Jack Knott | First | -- |
| Monday, September 2 |
| » Defeated White Sox (63-61), 6-1 | Tiger Stadium (50-24) | 82-44 | Won 2 |
| » Starters: John Whitehead vs Schoolboy Rowe | First | -- |
| » Defeated White Sox (63-62), 5-0 | Tiger Stadium (51-24) | 83-44 | Won 3 |
| » Starters: Sad Sam Jones vs Elden Auker | First | -- |
| Saturday, September 7 |
| » Defeated Athletics (51-72), 9-7 | Shibe Park (4-3) | 84-44 | Won 4 |
| » Starters: Tommy Bridges vs Bill Ferrazzi | First | -- |
| » Defeated Athletics (51-73), 15-1 | Shibe Park (5-3) | 85-44 | Won 5 |
| » Starters: Elden Auker vs Bill Dietrich | First | -- |
| Sunday, September 8 |
| » Lost to Senators (56-75), 4-3 | Griffith Stadium (5-3) | 85-45 | |
| » Starters: Roxie Lawson vs Bump Hadley | First | -- |
| Monday, September 9 |
| » Defeated Senators (56-76), 5-4 | Griffith Stadium (6-3) | 86-45 | |
| » Starters: General Crowder vs Jack Russell | First | -- |
| Tuesday, September 10 |
| » Lost to Senators (57-76), 6-0 | Griffith Stadium (6-4) | 86-46 | |
| » Starters: Schoolboy Rowe vs Bobo Newsom | First | -- |
| Wednesday, September 11 |
| » Lost to Senators (58-76), 4-3 | Griffith Stadium (6-5) | 86-47 | Lost 2 |
| » Starters: Tommy Bridges vs Ed Linke | First | -- |
| Thursday, September 12 |
| » Defeated Yankees (78-55), 8-5 | Yankee Stadium (4-3) | 87-47 | |
| » Starters: Elden Auker vs Red Ruffing | First | -- |
| Friday, September 13 |
| » Defeated Yankees (78-56), 13-5 | Yankee Stadium (5-3) | 88-47 | Won 2 |
| » Starters: Schoolboy Rowe vs Lefty Gomez | First | -- |
| Saturday, September 14 |
| » Lost to Yankees (79-56), 2-1 | Yankee Stadium (5-4) | 88-48 | |
| » Starters: General Crowder vs Johnny Broaca | First | -- |
| » Defeated Yankees (79-57), 5-1 | Yankee Stadium (6-4) | 89-48 | |
| » Starters: Roxie Lawson vs Jumbo Brown | First | -- |
| Sunday, September 15 |
| » Lost to Yankees (80-57), 8-7 | Yankee Stadium (6-5) | 89-49 | |
| » Starters: Joe Sullivan vs Vito Tamulis | First | -- |
| Monday, September 16 |
| » Defeated Red Sox (71-71), 5-3 | Fenway Park (6-2) | 90-49 | |
| » Starters: Tommy Bridges vs Jack Wilson | First | -- |
| Tuesday, September 17 |
| » Lost to Red Sox (72-71), 5-4 | Fenway Park (6-3) | 90-50 | |
| » Starters: Elden Auker vs Wes Ferrell | First | -- |
| Wednesday, September 18 |
| » Lost to Red Sox (73-71), 4-3 | Fenway Park (6-4) | 90-51 | Lost 2 |
| » Starters: Schoolboy Rowe vs Rube Walberg | First | -- |
| Thursday, September 19 |
| » Lost to Red Sox (74-71), 4-1 | Fenway Park (6-5) | 90-52 | Lost 3 |
| » Starters: General Crowder vs Lefty Grove | First | -- |
| Saturday, September 21 |
| » Defeated Browns (60-83), 6-2 | Tiger Stadium (52-24) | 91-52 | |
| » Starters: Sugar Cain vs Tommy Bridges | First | -- |
| » Defeated Browns (60-84), 2-0 | Tiger Stadium (53-24) | 92-52 | Won 2 |
| » Starters: Ivy Andrews vs Elden Auker | First | -- |
| Sunday, September 22 |
| » Lost to Browns (61-84), 1-0 | Tiger Stadium (53-25) | 92-53 | |
| » Starters: Earl Caldwell vs Schoolboy Rowe | First | -- |
| Tuesday, September 24 |
| » Lost to Indians (78-70), 14-7 | League Park II (6-4) | 92-54 | Lost 2 |
| » Starters: General Crowder vs Willis Hudlin | First | -- |
| Wednesday, September 25 |
| » Lost to Indians (79-70), 3-2 | League Park II (6-5) | 92-55 | Lost 3 |
| » Starters: Elden Auker vs Lloyd Brown | First | -- |
| Friday, September 27 |
| Future Tiger Dave Wickersham is born in Erie, PA. |
| Saturday, September 28 |
| » Lost to White Sox (72-77), 6-3 | Comiskey Park I (2-6) | 92-56 | Lost 4 |
| » Starters: Tommy Bridges vs Sad Sam Jones | First | -- |
| » Defeated White Sox (72-78), 8-3 | Comiskey Park I (3-6) | 93-56 | |
| » Starters: Schoolboy Rowe vs Monty Stratton | First | -- |
| Sunday, September 29 |
| » Lost to White Sox (73-78), 3-2 | Comiskey Park I (3-7) | 93-57 | |
| » Starters: General Crowder vs Vern Kennedy | First | -- |
| » Lost to White Sox (74-78), 14-2 | Comiskey Park I (3-8) | 93-58 | Lost 2 |
| » Starters: Elden Auker vs Les Tietje | First | -- |
| Future Tiger Bob Anderson is born in East Chicago, IN. |
| Saturday, October 12 |
| Future Tiger Bobo Osborne is born. |
| Wednesday, October 30 |
| Future Tiger Jim Perry is born in Williamston, NC. |
| Sunday, December 8 |
| Former Tiger Baldy Louden dies in Piedmont, WV at the age of 51. |
| Thursday, December 19 |
| Future Tiger Tony Taylor is born in Central Alava, Cuba. |
Game information provided by Retrosheet (www.retrosheet.org) |