| Thursday, January 10 |
| Future Indian Ted Bowsfield is born in Vernon, BC. |
| Thursday, January 17 |
| Future Indian Dick Brown is born in Shinnston, WV. |
| Tuesday, February 19 |
| Future Indian Russ Nixon is born in Cleves, OH. |
| Sunday, April 14 |
| Future Indian Marty Keough is born in Oakland, CA. |
| Tuesday, April 16 |
| » Defeated Browns (0-1), 2-1 | Sportsman's Park III (1-0) | 1-0 | |
| » Starters: Mel Harder vs Bobo Newsom | First | -- |
| » Major-league debuts: Beau Bell (Browns) |
| Wednesday, April 17 |
| » Major-league debuts: Jesse Hill (Yankees) |
| Saturday, April 20 |
| » Defeated Tigers (1-3), 2-1 | Tiger Stadium (1-0) | 2-0 | Won 2 |
| » Starters: Oral Hildebrand vs Elden Auker | First | -- |
| » Major-league debuts: Joe Sullivan (Tigers) |
| Sunday, April 21 |
| » Lost to Tigers (2-3), 3-2 | Tiger Stadium (1-1) | 2-1 | |
| » Starters: Monte Pearson vs Carl Fischer | Second | 1 out |
| Monday, April 22 |
| » Defeated Tigers (2-4), 5-0 | Tiger Stadium (2-1) | 3-1 | |
| » Starters: Willis Hudlin vs Tommy Bridges | Second | 1 out |
| Tuesday, April 23 |
| » Defeated Browns (2-3), 7-6 | League Park II (1-0) | 4-1 | Won 2 |
| » Starters: Bob Weiland vs Mel Harder | Second | 1 out |
| Wednesday, April 24 |
| » Defeated Browns (2-4), 3-2 | League Park II (2-0) | 5-1 | Won 3 |
| » Starters: Fay Thomas vs Oral Hildebrand | Second | ½ out |
| Thursday, April 25 |
| » Defeated Browns (2-5), 7-6 | League Park II (3-0) | 6-1 | Won 4 |
| » Starters: Jack Knott vs Monte Pearson | First | -- |
| Friday, April 26 |
| » Defeated Tigers (2-8), 11-3 | League Park II (4-0) | 7-1 | Won 5 |
| » Starters: Elden Auker vs Willis Hudlin | First | -- |
| Saturday, April 27 |
| » Defeated Tigers (2-9), 9-2 | League Park II (5-0) | 8-1 | Won 6 |
| » Starters: Tommy Bridges vs Mel Harder | First | -- |
| Sunday, April 28 |
| » Lost to Tigers (3-9), 5-3 | League Park II (5-1) | 8-2 | |
| » Starters: Joe Sullivan vs Oral Hildebrand | First | -- |
| Future Indian Pedro Ramos is born in Pinar Del Rio, Cuba. |
| Wednesday, May 1 |
| » Defeated White Sox (9-4), 11-5 | League Park II (6-1) | 9-2 | |
| » Starters: Sad Sam Jones vs Willis Hudlin | First | -- |
| Saturday, May 4 |
| » Lost to Athletics (3-11), 12-1 | League Park II (6-2) | 9-3 | |
| » Starters: Roy Mahaffey vs Mel Harder | First | -- |
| Monday, May 6 |
| » Lost to Red Sox (9-6), 2-1 | League Park II (6-3) | 9-4 | Lost 2 |
| » Starters: Fritz Ostermueller vs Oral Hildebrand | Second | 1 out |
| Wednesday, May 8 |
| » Defeated Red Sox (9-7), 2-0 | League Park II (7-3) | 10-4 | |
| » Starters: Lefty Grove vs Monte Pearson | Second | 1½ out |
| Thursday, May 9 |
| » Defeated Yankees (9-8), 5-0 | League Park II (8-3) | 11-4 | Won 2 |
| » Starters: Red Ruffing vs Mel Harder | First | -- |
| Friday, May 10 |
| » Lost to Yankees (10-8), 6-3 | League Park II (8-4) | 11-5 | |
| » Starters: Vito Tamulis vs Oral Hildebrand | First | -- |
| Saturday, May 11 |
| » Lost to Yankees (11-8), 10-4 | League Park II (8-5) | 11-6 | Lost 2 |
| » Starters: Johnny Allen vs Thornton Lee | Second | 1½ out |
| Monday, May 13 |
| Future Indian Bill Dailey is born in Arlington, VA. |
| Tuesday, May 14 |
| » Defeated Senators (11-10), 4-2 | League Park II (9-5) | 12-6 | |
| » Starters: Earl Whitehill vs Mel Harder | Second | 1 out |
| Wednesday, May 15 |
| » Defeated Senators (11-11), 5-4 | League Park II (10-5) | 13-6 | Won 2 |
| » Starters: Bobby Burke vs Oral Hildebrand | Second | 1 out |
| Thursday, May 16 |
| » Lost to Yankees (13-10), 10-0 | Yankee Stadium (0-1) | 13-7 | |
| » Starters: Willis Hudlin vs Vito Tamulis | Second | 1½ out |
| Friday, May 17 |
| » Lost to Yankees (14-10), 4-2 | Yankee Stadium (0-2) | 13-8 | Lost 2 |
| » Starters: Monte Pearson vs Johnny Allen | Second | 1½ out |
| Saturday, May 18 |
| » Lost to Yankees (15-10), 3-0 | Yankee Stadium (0-3) | 13-9 | Lost 3 |
| » Starters: Mel Harder vs Lefty Gomez | Third | 2½ out |
| Sunday, May 19 |
| » Defeated Yankees (15-11), 1-0 | Yankee Stadium (1-3) | 14-9 | |
| » Starters: Lefty Stewart vs Red Ruffing | Second | 2½ out |
| Monday, May 20 |
| » Defeated Red Sox (13-12), 4-1 | Fenway Park (1-0) | 15-9 | Won 2 |
| » Starters: Oral Hildebrand vs Lefty Grove | Second | 1½ out |
| Tuesday, May 21 |
| » Lost to Red Sox (14-12), 7-2 | Fenway Park (1-1) | 15-10 | |
| » Starters: Willis Hudlin vs Fritz Ostermueller | Second | 2½ out |
| Wednesday, May 22 |
| » Lost to Red Sox (15-12), 12-5 | Fenway Park (1-2) | 15-11 | Lost 2 |
| » Starters: Monte Pearson vs Wes Ferrell | Third | 2½ out |
| Friday, May 24 |
| » Defeated Athletics (8-18), 12-2 | Shibe Park (1-0) | 16-11 | |
| » Starters: Mel Harder vs Whitey Wilshere | Second | 1½ out |
| Saturday, May 25 |
| » Defeated Athletics (8-19), 9-6 | Shibe Park (2-0) | 17-11 | Won 2 |
| » Starters: Oral Hildebrand vs Roy Mahaffey | Third | 2 out |
| » Lost to Athletics (9-19), 6-1 | Shibe Park (2-1) | 17-12 | |
| » Starters: Willis Hudlin vs Bill Dietrich | Third | 2 out |
| Sunday, May 26 |
| » Lost to Senators (16-15), 9-4 | Griffith Stadium (0-1) | 17-13 | Lost 2 |
| » Starters: Lefty Stewart vs Bump Hadley | Third | 3 out |
| Monday, May 27 |
| » Lost to Senators (17-15), 6-5 | Griffith Stadium (0-2) | 17-14 | Lost 3 |
| » Starters: Monte Pearson vs Earl Whitehill | Third | 3 out |
| Future Indian Jerry Kindall is born in St. Paul, MN. |
| Tuesday, May 28 |
| » Defeated Senators (17-16), 5-4 | Griffith Stadium (1-2) | 18-14 | |
| » Starters: Mel Harder vs Bobo Newsom | Third | 2 out |
| Thursday, May 30 |
| » Lost to White Sox (21-12), 8-4 | Comiskey Park I (0-1) | 18-15 | |
| » Starters: Oral Hildebrand vs John Whitehead | Third | 3 out |
| » Defeated White Sox (21-13), 4-0 | Comiskey Park I (1-1) | 19-15 | |
| » Starters: Willis Hudlin vs Carl Fischer | Third | 3 out |
| Friday, May 31 |
| » Defeated White Sox (21-14), 6-2 | Comiskey Park I (2-1) | 20-15 | Won 2 |
| » Starters: Clint Brown vs Vern Kennedy | Third | 2½ out |
| Saturday, June 1 |
| » Lost to Browns (10-24), 7-3 | Sportsman's Park III (1-1) | 20-16 | |
| » Starters: Monte Pearson vs Dick Coffman | Third | 2½ out |
| » Defeated Browns (10-25), 4-2 | Sportsman's Park III (2-1) | 21-16 | |
| » Starters: Lefty Stewart vs Fay Thomas | Third | 2½ out |
| Future Indian Jack Kralick is born in Youngstown, OH. |
| Sunday, June 2 |
| » Defeated Browns (10-26), 6-2 | Sportsman's Park III (3-1) | 22-16 | Won 2 |
| » Starters: Mel Harder vs Russ Van Atta | Third | 2½ out |
| Monday, June 3 |
| » Defeated Browns (10-27), 11-4 | Sportsman's Park III (4-1) | 23-16 | Won 3 |
| » Starters: Oral Hildebrand vs Jim Walkup | Third | 2½ out |
| Wednesday, June 5 |
| » Lost to Tigers (22-18), 5-4 | Tiger Stadium (2-2) | 23-17 | |
| » Starters: Willis Hudlin vs Tommy Bridges | Second | 2½ out |
| » Tied Tigers, 4-4 | Tiger Stadium (2-2) | 23-17 | |
| » Starters: Clint Brown vs Joe Sullivan | Second | 2½ out |
| Thursday, June 6 |
| » Lost to Tigers (23-18), 10-9 | Tiger Stadium (2-3) | 23-18 | Lost 2 |
| » Starters: Lefty Stewart vs Schoolboy Rowe | Third | 3 out |
| Saturday, June 8 |
| » Defeated Browns (12-28), 3-2 | League Park II (11-5) | 24-18 | |
| » Starters: Sugar Cain vs Mel Harder | Third | 2 out |
| Sunday, June 9 |
| » Lost to Browns (13-28), 2-1 | League Park II (11-6) | 24-19 | |
| » Starters: Fay Thomas vs Oral Hildebrand | Third | 2½ out |
| Tuesday, June 11 |
| » Lost to Athletics (18-25), 4-2 | League Park II (11-7) | 24-20 | Lost 2 |
| » Starters: George Blaeholder vs Willis Hudlin | Third | 4½ out |
| » Lost to Athletics (19-25), 5-1 | League Park II (11-8) | 24-21 | Lost 3 |
| » Starters: Roy Mahaffey vs Clint Brown | Third | 4½ out |
| Former Indian Fred Abbott dies in Los Angeles, CA at the age of 61. |
| Wednesday, June 12 |
| » Lost to Athletics (20-25), 7-5 | League Park II (11-9) | 24-22 | Lost 4 |
| » Starters: Al Benton vs Mel Harder | Fourth | 5 out |
| Thursday, June 13 |
| » Defeated Athletics (20-26), 6-3 | League Park II (12-9) | 25-22 | |
| » Starters: Whitey Wilshere vs Oral Hildebrand | Fourth | 5 out |
| Friday, June 14 |
| » Lost to Athletics (21-26), 5-4 | League Park II (12-10) | 25-23 | |
| » Starters: Roy Mahaffey vs Monte Pearson | Fourth | 6 out |
| Saturday, June 15 |
| » Defeated Red Sox (26-25), 9-7 | League Park II (13-10) | 26-23 | |
| » Starters: Wes Ferrell vs Ralph Winegarner | Fourth | 6 out |
| Sunday, June 16 |
| » Defeated Red Sox (26-26), 4-0 | League Park II (14-10) | 27-23 | Won 2 |
| » Starters: Lefty Grove vs Mel Harder | Fourth | 5 out |
| » Defeated Red Sox (26-27), 9-3 | League Park II (15-10) | 28-23 | Won 3 |
| » Starters: Johnny Welch vs Willis Hudlin | Fourth | 5 out |
| Monday, June 17 |
| » Defeated Red Sox (26-28), 11-2 | League Park II (16-10) | 29-23 | Won 4 |
| » Starters: Gordon Rhodes vs Oral Hildebrand | Third | 4½ out |
| Wednesday, June 19 |
| » Lost to Senators (26-28), 11-8 | League Park II (16-11) | 29-24 | |
| » Starters: Bump Hadley vs Thornton Lee | Third | 5½ out |
| » Defeated Senators (26-29), 10-5 | League Park II (17-11) | 30-24 | |
| » Starters: Jack Russell vs Lefty Stewart | Third | 5½ out |
| Thursday, June 20 |
| » Defeated Senators (26-30), 8-6 | League Park II (18-11) | 31-24 | Won 2 |
| » Starters: Earl Whitehill vs Mel Harder | Second | 5½ out |
| Saturday, June 22 |
| » Defeated Yankees (37-21), 12-6 | League Park II (19-11) | 32-24 | Won 3 |
| » Starters: Johnny Broaca vs Oral Hildebrand | Second | 4 out |
| Sunday, June 23 |
| » Defeated Yankees (37-22), 6-5 | League Park II (20-11) | 33-24 | Won 4 |
| » Starters: Lefty Gomez vs Willis Hudlin | Second | 3 out |
| Monday, June 24 |
| » Lost to Yankees (38-22), 4-1 | League Park II (20-12) | 33-25 | |
| » Starters: Vito Tamulis vs Thornton Lee | Second | 4 out |
| Tuesday, June 25 |
| » Defeated Yankees (38-23), 5-4 | League Park II (21-12) | 34-25 | |
| » Starters: Johnny Allen vs Mel Harder | Second | 3 out |
| Future Indian Don Demeter is born in Oklahoma City, OK. |
| Friday, June 28 |
| » Defeated White Sox (31-26), 6-5 | League Park II (22-12) | 35-25 | Won 2 |
| » Starters: John Whitehead vs Oral Hildebrand | Second | 3 out |
| Saturday, June 29 |
| » Defeated White Sox (31-27), 6-5 | League Park II (23-12) | 36-25 | Won 3 |
| » Starters: Ray Phelps vs Willis Hudlin | Second | 3 out |
| Sunday, June 30 |
| » Defeated White Sox (31-28), 3-2 | League Park II (24-12) | 37-25 | Won 4 |
| » Starters: Ted Lyons vs Monte Pearson | Second | 2½ out |
| » Lost to White Sox (32-28), 8-0 | League Park II (24-13) | 37-26 | |
| » Starters: Vern Kennedy vs Mel Harder | Second | 2½ out |
| Monday, July 1 |
| » Lost to Tigers (39-29), 4-1 | Tiger Stadium (2-4) | 37-27 | Lost 2 |
| » Starters: Thornton Lee vs Elden Auker | Second | 3 out |
| Tuesday, July 2 |
| » Lost to Tigers (40-29), 8-3 | Tiger Stadium (2-5) | 37-28 | Lost 3 |
| » Starters: Lefty Stewart vs Tommy Bridges | Third | 4 out |
| Wednesday, July 3 |
| » Lost to Tigers (41-29), 11-7 | Tiger Stadium (2-6) | 37-29 | Lost 4 |
| » Starters: Oral Hildebrand vs Vic Sorrell | Third | 5 out |
| Thursday, July 4 |
| » Lost to Tigers (42-29), 6-5 | League Park II (24-14) | 37-30 | Lost 5 |
| » Starters: General Crowder vs Mel Harder | Fourth | 6 out |
| » Lost to Tigers (43-29), 10-4 | League Park II (24-15) | 37-31 | Lost 6 |
| » Starters: Schoolboy Rowe vs Willis Hudlin | Fourth | 6 out |
| Saturday, July 6 |
| » Lost to White Sox (37-28), 7-6 | Comiskey Park I (2-2) | 37-32 | Lost 7 |
| » Starters: Monte Pearson vs Vern Kennedy | Fourth | 6½ out |
| Sunday, July 7 |
| » Lost to White Sox (38-28), 2-0 | Comiskey Park I (2-3) | 37-33 | Lost 8 |
| » Starters: Oral Hildebrand vs Ted Lyons | Fourth | 7 out |
| » Defeated White Sox (38-29), 7-6 | Comiskey Park I (3-3) | 38-33 | |
| » Starters: Thornton Lee vs Sad Sam Jones | Fourth | 7 out |
| Thursday, July 11 |
| » Lost to Yankees (46-26), 8-1 | Yankee Stadium (1-4) | 38-34 | |
| » Starters: Mel Harder vs Johnny Allen | Fourth | 8 out |
| Friday, July 12 |
| » Lost to Yankees (47-26), 5-2 | Yankee Stadium (1-5) | 38-35 | Lost 2 |
| » Starters: Monte Pearson vs Red Ruffing | Fourth | 9 out |
| Saturday, July 13 |
| » Defeated Red Sox (40-38), 4-2 | Fenway Park (2-2) | 39-35 | |
| » Starters: Willis Hudlin vs Rube Walberg | Fourth | 8 out |
| Sunday, July 14 |
| » Lost to Red Sox (41-38), 14-3 | Fenway Park (2-3) | 39-36 | |
| » Starters: Oral Hildebrand vs Wes Ferrell | Fourth | 8½ out |
| » Tied Red Sox, 2-2 | Fenway Park (2-3) | 39-36 | |
| » Starters: Thornton Lee vs Fritz Ostermueller | Fourth | 8½ out |
| Wednesday, July 17 |
| » Lost to Red Sox (42-38), 13-5 | Fenway Park (2-4) | 39-37 | Lost 2 |
| » Starters: Mel Harder vs Joe Cascarella | Fifth | 10 out |
| » Lost to Red Sox (43-38), 3-1 | Fenway Park (2-5) | 39-38 | Lost 3 |
| » Starters: Monte Pearson vs Lefty Grove | Fifth | 10 out |
| Thursday, July 18 |
| » Lost to Athletics (35-42), 7-5 | Shibe Park (2-2) | 39-39 | Lost 4 |
| » Starters: Willis Hudlin vs Johnny Marcum | Fifth | 10 out |
| Friday, July 19 |
| » Major-league debuts: Tom Carey (Browns) |
| Saturday, July 20 |
| » Defeated Athletics (35-43), 15-3 | Shibe Park (3-2) | 40-39 | |
| » Starters: Thornton Lee vs Bill Dietrich | Fifth | 9½ out |
| » Lost to Athletics (36-43), 5-2 | Shibe Park (3-3) | 40-40 | |
| » Starters: Ralph Winegarner vs Roy Mahaffey | Fifth | 9½ out |
| Sunday, July 21 |
| » Defeated Athletics (36-44), 6-4 | Shibe Park (4-3) | 41-40 | |
| » Starters: Mel Harder vs George Blaeholder | Fifth | 9 out |
| Monday, July 22 |
| » Defeated Senators (36-50), 6-4 | Griffith Stadium (2-2) | 42-40 | Won 2 |
| » Starters: Lefty Stewart vs Ed Linke | Fifth | 8½ out |
| Wednesday, July 24 |
| » Defeated Senators (36-51), 10-6 | Griffith Stadium (3-2) | 43-40 | Won 3 |
| » Starters: Lloyd Brown vs Earl Whitehill | Fourth | 7½ out |
| » Defeated Senators (36-52), 13-8 | Griffith Stadium (4-2) | 44-40 | Won 4 |
| » Starters: Willis Hudlin vs Bump Hadley | Fourth | 7½ out |
| Friday, July 26 |
| » Lost to Tigers (55-35), 8-2 | League Park II (24-16) | 44-41 | |
| » Starters: Elden Auker vs Thornton Lee | Fourth | 8½ out |
| Saturday, July 27 |
| » Lost to Tigers (56-35), 6-2 | League Park II (24-17) | 44-42 | Lost 2 |
| » Starters: Tommy Bridges vs Mel Harder | Fourth | 9½ out |
| Sunday, July 28 |
| » Lost to Tigers (57-35), 14-6 | League Park II (24-18) | 44-43 | Lost 3 |
| » Starters: Schoolboy Rowe vs Lefty Stewart | Fifth | 10½ out |
| Monday, July 29 |
| » Defeated Tigers (57-36), 6-5 | League Park II (25-18) | 45-43 | |
| » Starters: General Crowder vs Willis Hudlin | Fifth | 9½ out |
| Tuesday, July 30 |
| » Lost to White Sox (50-37), 8-6 | Comiskey Park I (3-4) | 45-44 | |
| » Starters: Monte Pearson vs Vern Kennedy | Fifth | 9½ out |
| Wednesday, July 31 |
| » Lost to White Sox (51-37), 6-4 | Comiskey Park I (3-5) | 45-45 | Lost 2 |
| » Starters: Mel Harder vs Ray Phelps | Fifth | 10½ out |
| Thursday, August 1 |
| » Defeated White Sox (51-38), 8-3 | Comiskey Park I (4-5) | 46-45 | |
| » Starters: Thornton Lee vs Carl Fischer | Fifth | 10½ out |
| Saturday, August 3 |
| » Lost to Tigers (60-37), 5-4 | Tiger Stadium (2-7) | 46-46 | |
| » Starters: Willis Hudlin vs Elden Auker | Fifth | 12½ out |
| » Lost to Tigers (61-37), 7-3 | Tiger Stadium (2-8) | 46-47 | Lost 2 |
| » Starters: Monte Pearson vs Schoolboy Rowe | Fifth | 12½ out |
| Sunday, August 4 |
| » Lost to Tigers (62-37), 7-0 | Tiger Stadium (2-9) | 46-48 | Lost 3 |
| » Starters: Mel Harder vs Tommy Bridges | Fifth | 13½ out |
| Monday, August 5 |
| » Defeated White Sox (51-42), 4-2 | League Park II (26-18) | 47-48 | |
| » Manager: Steve O'Neill |
| » Starters: Vern Kennedy vs Ralph Winegarner | Fifth | 13 out |
| Wednesday, August 7 |
| » Defeated White Sox (51-43), 5-2 | League Park II (27-18) | 48-48 | Won 2 |
| » Starters: Carl Fischer vs Willis Hudlin | Fifth | 13 out |
| » Lost to White Sox (52-43), 2-1 | League Park II (27-19) | 48-49 | |
| » Starters: Ray Phelps vs Thornton Lee | Fifth | 13 out |
| Thursday, August 8 |
| » Defeated Browns (33-63), 14-8 | Sportsman's Park III (5-1) | 49-49 | |
| » Starters: Monte Pearson vs Sugar Cain | Fifth | 13½ out |
| » Lost to Browns (34-63), 9-5 | Sportsman's Park III (5-2) | 49-50 | |
| » Starters: Lloyd Brown vs Jack Knott | Fifth | 13½ out |
| Friday, August 9 |
| » Defeated Browns (34-64), 5-3 | Sportsman's Park III (6-2) | 50-50 | |
| » Starters: Mel Harder vs Russ Van Atta | Fifth | 13½ out |
| Saturday, August 10 |
| » Lost to Browns (35-64), 6-5 | Sportsman's Park III (6-3) | 50-51 | |
| » Starters: Monte Pearson vs Ivy Andrews | Fifth | 14½ out |
| Sunday, August 11 |
| » Defeated Browns (35-65), 10-7 | Sportsman's Park III (7-3) | 51-51 | |
| » Starters: Willis Hudlin vs Jim Walkup | Fifth | 14½ out |
| » Tied Browns, 7-7 | Sportsman's Park III (7-3) | 51-51 | |
| » Starters: Thornton Lee vs Fay Thomas | Fifth | 14½ out |
| Tuesday, August 13 |
| » Lost to Yankees (60-42), 8-2 | League Park II (27-20) | 51-52 | |
| » Starters: Red Ruffing vs Lefty Stewart | Fifth | 14½ out |
| Future Indian Mudcat Grant is born in Lacoochee, FL. |
| Wednesday, August 14 |
| » Defeated Yankees (60-43), 7-6 | League Park II (28-20) | 52-52 | |
| » Starters: Vito Tamulis vs Mel Harder | Fifth | 14½ out |
| Thursday, August 15 |
| » Lost to Yankees (61-43), 3-1 | League Park II (28-21) | 52-53 | |
| » Starters: Johnny Broaca vs Willis Hudlin | Fifth | 15½ out |
| Friday, August 16 |
| » Defeated Yankees (61-44), 8-5 | League Park II (29-21) | 53-53 | |
| » Starters: Johnny Allen vs Monte Pearson | Fifth | 14½ out |
| Saturday, August 17 |
| » Defeated Senators (46-62), 8-7 | League Park II (30-21) | 54-53 | Won 2 |
| » Starters: Earl Whitehill vs Thornton Lee | Fifth | 14 out |
| » Defeated Senators (46-63), 5-0 | League Park II (31-21) | 55-53 | Won 3 |
| » Starters: Bobo Newsom vs Lloyd Brown | Fifth | 14 out |
| Sunday, August 18 |
| » Lost to Senators (47-63), 4-2 | League Park II (31-22) | 55-54 | |
| » Starters: Ed Linke vs Mel Harder | Fifth | 14½ out |
| » Defeated Senators (47-64), 13-4 | League Park II (32-22) | 56-54 | |
| » Starters: Phil Hensiek vs Ralph Winegarner | Fifth | 14½ out |
| Monday, August 19 |
| » Defeated Senators (47-65), 11-5 | League Park II (33-22) | 57-54 | Won 2 |
| » Starters: Bump Hadley vs Lefty Stewart | Fourth | 13½ out |
| Tuesday, August 20 |
| » Defeated Senators (47-66), 4-2 | League Park II (34-22) | 58-54 | Won 3 |
| » Starters: Bobo Newsom vs Willis Hudlin | Fifth | 12½ out |
| Wednesday, August 21 |
| » Lost to Athletics (49-59), 10-5 | League Park II (34-23) | 58-55 | |
| » Starters: Johnny Marcum vs Monte Pearson | Third | 13½ out |
| » Defeated Athletics (49-60), 3-0 | League Park II (35-23) | 59-55 | |
| » Starters: George Blaeholder vs Lloyd Brown | Third | 13½ out |
| Thursday, August 22 |
| » Lost to Athletics (50-60), 1-0 | League Park II (35-24) | 59-56 | |
| » Starters: Bill Dietrich vs Thornton Lee | Fifth | 13½ out |
| Friday, August 23 |
| » Defeated Athletics (50-61), 10-1 | League Park II (36-24) | 60-56 | |
| » Starters: Carl Doyle vs Mel Harder | Third | 13½ out |
| Saturday, August 24 |
| » Defeated Athletics (50-62), 2-0 | League Park II (37-24) | 61-56 | Won 2 |
| » Starters: George Turbeville vs Willis Hudlin | Third | 13½ out |
| Sunday, August 25 |
| » Lost to Red Sox (61-58), 5-4 | League Park II (37-25) | 61-57 | |
| » Starters: Fritz Ostermueller vs Oral Hildebrand | Fourth | 15 out |
| » Lost to Red Sox (62-58), 8-2 | League Park II (37-26) | 61-58 | Lost 2 |
| » Starters: Johnny Welch vs Lloyd Brown | Fourth | 15 out |
| Monday, August 26 |
| » Defeated Red Sox (62-59), 4-3 | League Park II (38-26) | 62-58 | |
| » Starters: Rube Walberg vs Monte Pearson | Third | 14½ out |
| Wednesday, August 28 |
| » Defeated Red Sox (62-60), 2-0 | League Park II (39-26) | 63-58 | Won 2 |
| » Starters: Lefty Grove vs Thornton Lee | Third | 15 out |
| » Defeated Red Sox (62-61), 3-1 | League Park II (40-26) | 64-58 | Won 3 |
| » Starters: Gordon Rhodes vs Mel Harder | Third | 15 out |
| Friday, August 30 |
| Future Indian Frank Funk is born in Washington, DC. |
| Saturday, August 31 |
| » Lost to White Sox (62-60), 5-0 | Comiskey Park I (4-6) | 64-59 | |
| » Starters: Willis Hudlin vs Vern Kennedy | Third | 16 out |
| Future Indian Frank Robinson is born in Beaumont, TX. |
| Sunday, September 1 |
| » Lost to White Sox (63-60), 9-6 | Comiskey Park I (4-7) | 64-60 | Lost 2 |
| » Starters: Oral Hildebrand vs Ray Phelps | Third | 16½ out |
| Monday, September 2 |
| » Lost to Browns (50-75), 4-1 | League Park II (40-27) | 64-61 | Lost 3 |
| » Starters: Ivy Andrews vs Mel Harder | Third | 17½ out |
| » Defeated Browns (50-76), 7-2 | League Park II (41-27) | 65-61 | |
| » Starters: Russ Van Atta vs Monte Pearson | Third | 17½ out |
| Thursday, September 5 |
| » Defeated Red Sox (64-65), 8-1 | Fenway Park (3-5) | 66-61 | Won 2 |
| » Starters: Willis Hudlin vs Lefty Grove | Third | 17½ out |
| » Lost to Red Sox (65-65), 6-1 | Fenway Park (3-6) | 66-62 | |
| » Starters: Thornton Lee vs Wes Ferrell | Third | 17½ out |
| Saturday, September 7 |
| » Defeated Red Sox (65-66), 5-3 | Fenway Park (4-6) | 67-62 | |
| » Starters: Mel Harder vs Rube Walberg | Third | 17½ out |
| » Defeated Red Sox (65-67), 5-4 | Fenway Park (5-6) | 68-62 | Won 2 |
| » Starters: Monte Pearson vs Gordon Rhodes | Third | 17½ out |
| Sunday, September 8 |
| » Lost to Yankees (75-53), 3-2 | Yankee Stadium (1-6) | 68-63 | |
| » Starters: Lloyd Brown vs Lefty Gomez | Third | 18 out |
| » Lost to Yankees (76-53), 5-4 | Yankee Stadium (1-7) | 68-64 | Lost 2 |
| » Starters: Thornton Lee vs Johnny Broaca | Third | 18 out |
| Monday, September 9 |
| » Lost to Yankees (77-53), 5-3 | Yankee Stadium (1-8) | 68-65 | Lost 3 |
| » Starters: Willis Hudlin vs Jumbo Brown | Third | 19 out |
| Tuesday, September 10 |
| » Lost to Yankees (78-53), 4-1 | Yankee Stadium (1-9) | 68-66 | Lost 4 |
| » Starters: Clint Brown vs Vito Tamulis | Third | 19 out |
| Wednesday, September 11 |
| » Defeated Yankees (78-54), 5-4 | Yankee Stadium (2-9) | 69-66 | |
| » Starters: Mel Harder vs Johnny Allen | Third | 18 out |
| Thursday, September 12 |
| » Lost to Senators (59-76), 3-0 | Griffith Stadium (4-3) | 69-67 | |
| » Starters: Monte Pearson vs Earl Whitehill | Third | 19 out |
| Friday, September 13 |
| » Lost to Senators (60-76), 5-3 | Griffith Stadium (4-4) | 69-68 | Lost 2 |
| » Starters: Thornton Lee vs Bump Hadley | Third | 20 out |
| Saturday, September 14 |
| » Lost to Senators (61-76), 5-1 | Griffith Stadium (4-5) | 69-69 | Lost 3 |
| » Starters: Lloyd Brown vs Bobo Newsom | Third | 20½ out |
| Sunday, September 15 |
| » Defeated Senators (61-77), 16-4 | Griffith Stadium (5-5) | 70-69 | |
| » Starters: Willis Hudlin vs Buck Rogers | Third | 19 out |
| » Defeated Senators (61-78), 6-3 | Griffith Stadium (6-5) | 71-69 | Won 2 |
| » Starters: Mel Harder vs Dick Lanahan | Third | 19 out |
| Monday, September 16 |
| » Defeated Athletics (55-81), 8-5 | Shibe Park (5-3) | 72-69 | Won 3 |
| » Starters: Clint Brown vs Johnny Marcum | Third | 19 out |
| Tuesday, September 17 |
| » Defeated Athletics (55-82), 5-3 | Shibe Park (6-3) | 73-69 | Won 4 |
| » Starters: Thornton Lee vs Vallie Eaves | Third | 18 out |
| Wednesday, September 18 |
| » Defeated Athletics (55-83), 10-5 | Shibe Park (7-3) | 74-69 | Won 5 |
| » Starters: Willis Hudlin vs Woody Upchurch | Third | 16½ out |
| » Defeated Athletics (55-84), 10-0 | Shibe Park (8-3) | 75-69 | Won 6 |
| » Starters: Mel Harder vs George Caster | Third | 16½ out |
| Saturday, September 21 |
| » Defeated White Sox (70-73), 7-3 | League Park II (42-27) | 76-69 | Won 7 |
| » Starters: Ted Lyons vs Monte Pearson | Third | 16½ out |
| Sunday, September 22 |
| » Defeated White Sox (70-74), 6-3 | League Park II (43-27) | 77-69 | Won 8 |
| » Starters: Sad Sam Jones vs Mel Harder | Third | 16 out |
| » Lost to White Sox (71-74), 9-2 | League Park II (43-28) | 77-70 | |
| » Starters: Monty Stratton vs Thornton Lee | Third | 16 out |
| Tuesday, September 24 |
| » Defeated Tigers (92-54), 14-7 | League Park II (44-28) | 78-70 | |
| » Starters: General Crowder vs Willis Hudlin | Third | 15 out |
| Wednesday, September 25 |
| » Defeated Tigers (92-55), 3-2 | League Park II (45-28) | 79-70 | Won 2 |
| » Starters: Elden Auker vs Lloyd Brown | Third | 14 out |
| Saturday, September 28 |
| » Defeated Browns (64-85), 3-0 | League Park II (46-28) | 80-70 | Won 3 |
| » Starters: Ivy Andrews vs Mel Harder | Third | 13 out |
| » Defeated Browns (64-86), 7-3 | League Park II (47-28) | 81-70 | Won 4 |
| » Starters: Earl Caldwell vs Thornton Lee | Third | 13 out |
| Sunday, September 29 |
| » Lost to Browns (65-86), 9-7 | League Park II (47-29) | 81-71 | |
| » Starters: Sugar Cain vs Monte Pearson | Third | 12 out |
| » Defeated Browns (65-87), 7-4 | League Park II (48-29) | 82-71 | |
| » Starters: Jack Knott vs Denny Galehouse | Third | 12 out |
| Wednesday, October 30 |
| Future Indian Jim Perry is born in Williamston, NC. |
| Saturday, November 30 |
| Future Indian Steve Hamilton is born in Columbia, KY. |
Game information provided by Retrosheet (www.retrosheet.org) |