| Monday, January 8 |
| Future White Sox Gene Freese is born in Wheeling, WV. |
| Friday, February 9 |
| Future White Sox Ted Wills is born in Fresno, CA. |
| Friday, March 9 |
| Future White Sox Jim Landis is born in Fresno, CA. |
| Tuesday, March 13 |
| Former White Sox Fielder Jones dies in Portland, OR at the age of 63. |
| Tuesday, April 17 |
| » Lost to Tigers (1-0), 8-3 | Comiskey Park I (0-1) | 0-1 | |
| » Starters: Firpo Marberry vs Sam Jones | Second | 1 out |
| » Major-league debuts: Zeke Bonura and Frenchy Bordagaray (White Sox) |
| Wednesday, April 18 |
| » Lost to Tigers (2-0), 6-5 | Comiskey Park I (0-2) | 0-2 | Lost 2 |
| » Starters: Vic Sorrell vs Whit Wyatt | Third | 2 out |
| Future White Sox Deacon Jones is born in White Plains, NY. |
| Thursday, April 19 |
| » Defeated Tigers (2-1), 9-8 | Comiskey Park I (1-2) | 1-2 | |
| » Starters: Schoolboy Rowe vs Phil Gallivan | Third | 1 out |
| Former White Sox Piano Legs Hickman dies in Morgantown, WV at the age of 59. |
| Sunday, April 22 |
| » Lost to Browns (2-2), 6-5 | Comiskey Park I (1-3) | 1-3 | |
| » Starters: Jim Weaver vs George Earnshaw | Sixth | 2 out |
| Tuesday, April 24 |
| » Lost to Tigers (4-1), 7-3 | Tiger Stadium (0-1) | 1-4 | Lost 2 |
| » Starters: Joe Heving vs Firpo Marberry | Eighth | 3 out |
| Wednesday, April 25 |
| » Defeated Tigers (4-2), 3-2 | Tiger Stadium (1-1) | 2-4 | |
| » Starters: Sam Jones vs Elden Auker | Fifth | 2½ out |
| Thursday, April 26 |
| » Lost to Tigers (5-2), 2-1 | Tiger Stadium (1-2) | 2-5 | |
| » Starters: Milt Gaston vs Vic Sorrell | Seventh | 3 out |
| Saturday, April 28 |
| » Defeated Browns (2-5), 5-2 | Sportsman's Park III (1-0) | 3-5 | |
| » Starters: George Earnshaw vs Bobo Newsom | Sixth | 3 out |
| Sunday, April 29 |
| » Lost to Browns (3-5), 6-2 | Sportsman's Park III (1-1) | 3-6 | |
| » Starters: Les Tietje vs Jim Weaver | Eighth | 3 out |
| Future White Sox Luis Aparicio is born in Maracaibo, Venezuela. |
| Monday, April 30 |
| » Defeated Indians (5-4), 20-10 | Comiskey Park I (2-3) | 4-6 | |
| » Starters: Monte Pearson vs Sam Jones | Eighth | 2½ out |
| » Major-league debuts: Denny Galehouse (Indians) |
| Tuesday, May 1 |
| » Lost to Indians (6-4), 12-1 | Comiskey Park I (2-4) | 4-7 | |
| » Starters: Willis Hudlin vs Milt Gaston | Eighth | 3½ out |
| Saturday, May 5 |
| » Lost to Athletics (7-8), 10-4 | Shibe Park (0-1) | 4-8 | Lost 2 |
| » Starters: George Earnshaw vs Sugar Cain | Eighth | 4½ out |
| Sunday, May 6 |
| » Lost to Senators (9-8), 5-0 | Griffith Stadium (0-1) | 4-9 | Lost 3 |
| » Starters: Sam Jones vs Tommy Thomas | Eighth | 5½ out |
| Monday, May 7 |
| » Lost to Senators (10-8), 17-7 | Griffith Stadium (0-2) | 4-10 | Lost 4 |
| » Starters: Joe Heving vs Monte Weaver | Eighth | 6½ out |
| Tuesday, May 8 |
| » Lost to Senators (11-8), 7-6 | Griffith Stadium (0-3) | 4-11 | Lost 5 |
| » Starters: Phil Gallivan vs Earl Whitehill | Seventh | 7½ out |
| Wednesday, May 9 |
| » Defeated Senators (11-9), 8-1 | Griffith Stadium (1-3) | 5-11 | |
| » Manager: Jimmy Dykes |
| » Starters: Milt Gaston vs Bobby Burke | Seventh | 6½ out |
| Thursday, May 10 |
| » Lost to Yankees (14-6), 13-3 | Yankee Stadium (0-1) | 5-12 | |
| » Starters: George Earnshaw vs Red Ruffing | Seventh | 7½ out |
| Friday, May 11 |
| » Lost to Yankees (15-6), 7-6 | Yankee Stadium (0-2) | 5-13 | Lost 2 |
| » Starters: Sam Jones vs Danny MacFayden | Seventh | 8½ out |
| Saturday, May 12 |
| » Lost to Yankees (16-6), 4-3 | Yankee Stadium (0-3) | 5-14 | Lost 3 |
| » Starters: Ted Lyons vs Johnny Allen | Eighth | 9½ out |
| Sunday, May 13 |
| » Lost to Red Sox (11-12), 14-2 | Fenway Park (0-1) | 5-15 | Lost 4 |
| » Starters: Milt Gaston vs Gordon Rhodes | Eighth | 10½ out |
| Future White Sox Leon Wagner is born in Chattanooga, TN. |
| Monday, May 14 |
| » Defeated Red Sox (11-13), 8-2 | Fenway Park (1-1) | 6-15 | |
| » Starters: George Earnshaw vs Hank Johnson | Seventh | 10 out |
| Thursday, May 17 |
| » Defeated Athletics (12-12), 7-2 | Comiskey Park I (3-4) | 7-15 | Won 2 |
| » Starters: Sugar Cain vs Sam Jones | Eighth | 9 out |
| Friday, May 18 |
| » Defeated Athletics (12-13), 5-4 | Comiskey Park I (4-4) | 8-15 | Won 3 |
| » Starters: Joe Cascarella vs Ted Lyons | Eighth | 8 out |
| Saturday, May 19 |
| » Defeated Athletics (12-14), 14-10 | Comiskey Park I (5-4) | 9-15 | Won 4 |
| » Starters: Johnny Marcum vs Milt Gaston | Eighth | 8 out |
| Sunday, May 20 |
| » Lost to Red Sox (13-15), 6-5 | Comiskey Park I (5-5) | 9-16 | |
| » Starters: George Pipgras vs George Earnshaw | Eighth | 8 out |
| Monday, May 21 |
| » Lost to Red Sox (14-15), 13-10 | Comiskey Park I (5-6) | 9-17 | Lost 2 |
| » Starters: Gordon Rhodes vs Phil Gallivan | Eighth | 8 out |
| Tuesday, May 22 |
| » Defeated Red Sox (14-16), 6-5 | Comiskey Park I (6-6) | 10-17 | |
| » Starters: Fritz Ostermueller vs Sam Jones | Eighth | 7 out |
| Wednesday, May 23 |
| » Defeated Yankees (18-12), 14-2 | Comiskey Park I (7-6) | 11-17 | Won 2 |
| » Starters: Red Ruffing vs Ted Lyons | Eighth | 6 out |
| Thursday, May 24 |
| » Lost to Yankees (19-12), 2-1 | Comiskey Park I (7-7) | 11-18 | |
| » Starters: Lefty Gomez vs Milt Gaston | Eighth | 7 out |
| Friday, May 25 |
| » Defeated Yankees (19-13), 7-5 | Comiskey Park I (8-7) | 12-18 | |
| » Starters: George Uhle vs George Earnshaw | Seventh | 6 out |
| Saturday, May 26 |
| » Lost to Senators (18-17), 9-7 | Comiskey Park I (8-8) | 12-19 | |
| » Starters: Alvin Crowder vs Phil Gallivan | Seventh | 7 out |
| Sunday, May 27 |
| » Lost to Senators (19-17), 9-6 | Comiskey Park I (8-9) | 12-20 | Lost 2 |
| » Starters: Monte Weaver vs Sam Jones | Seventh | 7 out |
| Monday, May 28 |
| » Defeated Senators (19-18), 11-7 | Comiskey Park I (9-9) | 13-20 | |
| » Starters: Tommy Thomas vs Ted Lyons | Seventh | 7 out |
| Tuesday, May 29 |
| » Lost to Indians (20-12), 5-0 | League Park II (0-1) | 13-21 | |
| » Starters: Milt Gaston vs Mel Harder | Eighth | 8 out |
| Wednesday, May 30 |
| » Defeated Indians (20-13), 8-7 | League Park II (1-1) | 14-21 | |
| » Starters: George Earnshaw vs Monte Pearson | Eighth | 8 out |
| » Lost to Indians (21-13), 5-4 | League Park II (1-2) | 14-22 | |
| » Starters: Les Tietje vs Willis Hudlin | Eighth | 8 out |
| Thursday, May 31 |
| » Defeated Indians (21-14), 12-5 | League Park II (2-2) | 15-22 | |
| » Starters: Sam Jones vs Belve Bean | Eighth | 7 out |
| Friday, June 1 |
| » Lost to Tigers (22-18), 3-1 | Comiskey Park I (9-10) | 15-23 | |
| » Starters: Schoolboy Rowe vs Ted Lyons | Eighth | 7½ out |
| Saturday, June 2 |
| » Lost to Tigers (23-18), 12-0 | Comiskey Park I (9-11) | 15-24 | Lost 2 |
| » Starters: Firpo Marberry vs Milt Gaston | Eighth | 7½ out |
| » Major-league debuts: Monty Stratton (White Sox) |
| Sunday, June 3 |
| » Lost to Tigers (24-18), 11-2 | Comiskey Park I (9-12) | 15-25 | Lost 3 |
| » Starters: Tommy Bridges vs George Earnshaw | Eighth | 8½ out |
| Tuesday, June 5 |
| » Defeated Browns (20-20), 8-2 | Comiskey Park I (10-12) | 16-25 | |
| » Starters: George Blaeholder vs Sam Jones | Eighth | 8 out |
| » Lost to Browns (21-20), 10-5 | Comiskey Park I (10-13) | 16-26 | |
| » Starters: Dick Coffman vs Les Tietje | Eighth | 8 out |
| Wednesday, June 6 |
| » Lost to Browns (22-20), 3-2 | Comiskey Park I (10-14) | 16-27 | Lost 2 |
| » Starters: Bump Hadley vs Ted Lyons | Eighth | 9 out |
| Thursday, June 7 |
| » Lost to Browns (23-20), 5-3 | Comiskey Park I (10-15) | 16-28 | Lost 3 |
| » Starters: Bobo Newsom vs Milt Gaston | Eighth | 10 out |
| Friday, June 8 |
| » Lost to Tigers (28-19), 13-5 | Tiger Stadium (1-3) | 16-29 | Lost 4 |
| » Starters: George Earnshaw vs Firpo Marberry | Eighth | 11 out |
| Saturday, June 9 |
| » Lost to Tigers (29-19), 8-5 | Tiger Stadium (1-4) | 16-30 | Lost 5 |
| » Starters: Whit Wyatt vs Vic Sorrell | Eighth | 12 out |
| Sunday, June 10 |
| » Defeated Tigers (29-20), 3-1 | Tiger Stadium (2-4) | 17-30 | |
| » Starters: Sam Jones vs Schoolboy Rowe | Eighth | 11 out |
| Wednesday, June 13 |
| » Lost to Senators (26-25), 11-3 | Griffith Stadium (1-4) | 17-31 | |
| » Starters: Ted Lyons vs Earl Whitehill | Eighth | 12 out |
| » Lost to Senators (27-25), 13-11 | Griffith Stadium (1-5) | 17-32 | Lost 2 |
| » Starters: Milt Gaston vs Jack Russell | Eighth | 12 out |
| Thursday, June 14 |
| » Lost to Senators (28-25), 5-1 | Griffith Stadium (1-6) | 17-33 | Lost 3 |
| » Starters: George Earnshaw vs Monte Weaver | Eighth | 12½ out |
| Friday, June 15 |
| » Lost to Senators (29-25), 8-7 | Griffith Stadium (1-7) | 17-34 | Lost 4 |
| » Starters: Sam Jones vs Alvin Crowder | Eighth | 13½ out |
| Saturday, June 16 |
| » Defeated Athletics (20-31), 9-7 | Shibe Park (1-1) | 18-34 | |
| » Starters: Ted Lyons vs Al Benton | Eighth | 14 out |
| » Lost to Athletics (21-31), 7-6 | Shibe Park (1-2) | 18-35 | |
| » Starters: Whit Wyatt vs Bill Dietrich | Eighth | 14 out |
| Sunday, June 17 |
| » Lost to Athletics (22-31), 3-2 | Shibe Park (1-3) | 18-36 | Lost 2 |
| » Starters: Milt Gaston vs Johnny Marcum | Eighth | 14½ out |
| Monday, June 18 |
| » Defeated Athletics (22-32), 3-2 | Shibe Park (2-3) | 19-36 | |
| » Starters: George Earnshaw vs Sugar Cain | Eighth | 13 out |
| » Defeated Athletics (22-33), 5-0 | Shibe Park (3-3) | 20-36 | Won 2 |
| » Starters: Les Tietje vs Al Benton | Eighth | 13 out |
| Wednesday, June 20 |
| » Lost to Red Sox (30-27), 14-9 | Fenway Park (1-2) | 20-37 | |
| » Starters: Sam Jones vs Wes Ferrell | Eighth | 14½ out |
| Thursday, June 21 |
| » Lost to Red Sox (31-27), 6-3 | Fenway Park (1-3) | 20-38 | Lost 2 |
| » Starters: Ted Lyons vs Hank Johnson | Eighth | 14 out |
| » Defeated Red Sox (31-28), 4-1 | Fenway Park (2-3) | 21-38 | |
| » Starters: Whit Wyatt vs Gordon Rhodes | Eighth | 14 out |
| Friday, June 22 |
| » Lost to Red Sox (32-28), 11-1 | Fenway Park (2-4) | 21-39 | |
| » Starters: Milt Gaston vs Fritz Ostermueller | Eighth | 14½ out |
| Future White Sox Russ Snyder is born in Oak, NE. |
| Saturday, June 23 |
| » Lost to Red Sox (33-28), 10-2 | Fenway Park (2-5) | 21-40 | Lost 2 |
| » Starters: Les Tietje vs Johnny Welch | Eighth | 16 out |
| Sunday, June 24 |
| » Lost to Yankees (36-24), 5-0 | Yankee Stadium (0-4) | 21-41 | Lost 3 |
| » Starters: Sam Jones vs Red Ruffing | Eighth | 17 out |
| Monday, June 25 |
| » Lost to Yankees (37-24), 13-2 | Yankee Stadium (0-5) | 21-42 | Lost 4 |
| » Starters: George Earnshaw vs Johnny Broaca | Eighth | 17 out |
| Tuesday, June 26 |
| » Lost to Yankees (38-24), 6-2 | Yankee Stadium (0-6) | 21-43 | Lost 5 |
| » Starters: Ted Lyons vs Danny MacFayden | Eighth | 18 out |
| Wednesday, June 27 |
| » Lost to Yankees (39-24), 8-7 | Yankee Stadium (0-7) | 21-44 | Lost 6 |
| » Starters: Milt Gaston vs Lefty Gomez | Eighth | 19 out |
| Thursday, June 28 |
| » Lost to Tigers (40-25), 8-7 | Tiger Stadium (2-5) | 21-45 | Lost 7 |
| » Starters: Sam Jones vs Firpo Marberry | Eighth | 20 out |
| Friday, June 29 |
| » Lost to Indians (33-29), 5-2 | Comiskey Park I (10-16) | 21-46 | Lost 8 |
| » Starters: Mel Harder vs Les Tietje | Eighth | 20½ out |
| Saturday, June 30 |
| » Defeated Indians (33-30), 2-1 | Comiskey Park I (11-16) | 22-46 | |
| » Starters: Willis Hudlin vs George Earnshaw | Eighth | 20 out |
| Sunday, July 1 |
| » Defeated Indians (33-31), 12-5 | Comiskey Park I (12-16) | 23-46 | Won 2 |
| » Starters: Monte Pearson vs Ted Lyons | Eighth | 20½ out |
| » Lost to Indians (34-31), 4-3 | Comiskey Park I (12-17) | 23-47 | |
| » Starters: Oral Hildebrand vs Milt Gaston | Eighth | 20½ out |
| Wednesday, July 4 |
| » Lost to Browns (31-35), 4-0 | Comiskey Park I (12-18) | 23-48 | Lost 2 |
| » Starters: Dick Coffman vs Sam Jones | Eighth | 20½ out |
| » Defeated Browns (31-36), 3-2 | Comiskey Park I (13-18) | 24-48 | |
| » Starters: George Blaeholder vs Les Tietje | Eighth | 20½ out |
| Thursday, July 5 |
| » Lost to Indians (37-34), 8-0 | League Park II (2-3) | 24-49 | |
| » Starters: George Earnshaw vs Oral Hildebrand | Eighth | 21½ out |
| Friday, July 6 |
| » Defeated Indians (37-35), 7-5 | League Park II (3-3) | 25-49 | |
| » Starters: Milt Gaston vs Ralph Winegarner | Eighth | 20½ out |
| » Major-league debuts: Jocko Conlan (White Sox) |
| Sunday, July 8 |
| » Lost to Indians (38-35), 5-1 | Cleveland Stadium (0-1) | 25-50 | |
| » Starters: Sam Jones vs Willis Hudlin | Eighth | 22½ out |
| » Lost to Indians (39-35), 10-5 | Cleveland Stadium (0-2) | 25-51 | Lost 2 |
| » Starters: Whit Wyatt vs Monte Pearson | Eighth | 22½ out |
| Thursday, July 12 |
| » Defeated Athletics (30-46), 3-2 | Comiskey Park I (14-18) | 26-51 | |
| » Starters: Sugar Cain vs George Earnshaw | Eighth | 22½ out |
| Saturday, July 14 |
| » Defeated Athletics (30-47), 10-5 | Comiskey Park I (15-18) | 27-51 | Won 2 |
| » Starters: Bill Dietrich vs Milt Gaston | Eighth | 22 out |
| Sunday, July 15 |
| » Lost to Athletics (31-47), 11-7 | Comiskey Park I (15-19) | 27-52 | |
| » Starters: Al Benton vs Les Tietje | Eighth | 23½ out |
| » Lost to Athletics (32-47), 10-5 | Comiskey Park I (15-20) | 27-53 | Lost 2 |
| » Starters: Johnny Marcum vs Phil Gallivan | Eighth | 23½ out |
| Monday, July 16 |
| » Lost to Red Sox (45-37), 5-4 | Comiskey Park I (15-21) | 27-54 | Lost 3 |
| » Starters: Hank Johnson vs Sam Jones | Eighth | 23 out |
| » Defeated Red Sox (45-38), 4-2 | Comiskey Park I (16-21) | 28-54 | |
| » Starters: Johnny Welch vs George Earnshaw | Eighth | 23 out |
| Tuesday, July 17 |
| » Lost to Red Sox (46-38), 6-2 | Comiskey Park I (16-22) | 28-55 | |
| » Starters: Wes Ferrell vs Les Tietje | Eighth | 24 out |
| Wednesday, July 18 |
| » Lost to Red Sox (47-38), 16-3 | Comiskey Park I (16-23) | 28-56 | Lost 2 |
| » Starters: Joe Mulligan vs Whit Wyatt | Eighth | 25 out |
| Thursday, July 19 |
| » Lost to Yankees (50-32), 4-3 | Comiskey Park I (16-24) | 28-57 | Lost 3 |
| » Starters: Johnny Murphy vs Milt Gaston | Eighth | 25½ out |
| Friday, July 20 |
| » Defeated Yankees (50-33), 7-6 | Comiskey Park I (17-24) | 29-57 | |
| » Starters: Johnny Broaca vs Sam Jones | Eighth | 24½ out |
| Saturday, July 21 |
| » Lost to Yankees (51-33), 6-2 | Comiskey Park I (17-25) | 29-58 | |
| » Starters: Lefty Gomez vs Les Tietje | Eighth | 25½ out |
| Sunday, July 22 |
| » Lost to Yankees (52-33), 8-2 | Comiskey Park I (17-26) | 29-59 | Lost 2 |
| » Starters: Johnny Allen vs Ted Lyons | Eighth | 26½ out |
| » Lost to Yankees (53-33), 15-2 | Comiskey Park I (17-27) | 29-60 | Lost 3 |
| » Starters: Jimmie DeShong vs George Earnshaw | Eighth | 26½ out |
| Monday, July 23 |
| » Lost to Senators (43-47), 11-5 | Comiskey Park I (17-28) | 29-61 | Lost 4 |
| » Starters: Earl Whitehill vs Milt Gaston | Eighth | 27½ out |
| Tuesday, July 24 |
| » Defeated Senators (43-48), 4-1 | Comiskey Park I (18-28) | 30-61 | |
| » Starters: Alvin Crowder vs Les Tietje | Eighth | 27½ out |
| Wednesday, July 25 |
| » Defeated Senators (43-49), 4-0 | Comiskey Park I (19-28) | 31-61 | Won 2 |
| » Starters: Lefty Stewart vs George Earnshaw | Eighth | 26½ out |
| Thursday, July 26 |
| » Defeated Senators (43-50), 9-0 | Comiskey Park I (20-28) | 32-61 | Won 3 |
| » Starters: Monte Weaver vs Sam Jones | Eighth | 25½ out |
| Saturday, July 28 |
| » Lost to Tigers (58-35), 11-1 | Comiskey Park I (20-29) | 32-62 | |
| » Starters: Schoolboy Rowe vs Ted Lyons | Eighth | 26½ out |
| Sunday, July 29 |
| » Lost to Tigers (59-35), 16-15 | Comiskey Park I (20-30) | 32-63 | Lost 2 |
| » Starters: Tommy Bridges vs George Earnshaw | Eighth | 26½ out |
| » Defeated Tigers (59-36), 6-4 | Comiskey Park I (21-30) | 33-63 | |
| » Starters: Firpo Marberry vs Les Tietje | Eighth | 26½ out |
| Monday, July 30 |
| » Lost to Browns (42-48), 4-3 | Sportsman's Park III (1-2) | 33-64 | |
| » Starters: Milt Gaston vs Dick Coffman | Eighth | 27 out |
| Tuesday, July 31 |
| » Defeated Browns (42-49), 5-2 | Sportsman's Park III (2-2) | 34-64 | |
| » Starters: Sam Jones vs George Blaeholder | Eighth | 26½ out |
| Wednesday, August 1 |
| » Defeated Browns (42-50), 10-6 | Sportsman's Park III (3-2) | 35-64 | Won 2 |
| » Starters: Ted Lyons vs Bump Hadley | Eighth | 26 out |
| » Defeated Browns (42-51), 4-2 | Sportsman's Park III (4-2) | 36-64 | Won 3 |
| » Starters: George Earnshaw vs Jack Knott | Eighth | 26 out |
| Thursday, August 2 |
| » Lost to Browns (43-51), 9-8 | Sportsman's Park III (4-3) | 36-65 | |
| » Starters: Les Tietje vs Dick Coffman | Eighth | 27 out |
| Friday, August 3 |
| » Lost to Tigers (63-37), 14-0 | Tiger Stadium (2-6) | 36-66 | Lost 2 |
| » Starters: Milt Gaston vs Schoolboy Rowe | Eighth | 28 out |
| Saturday, August 4 |
| » Lost to Tigers (64-37), 16-4 | Tiger Stadium (2-7) | 36-67 | Lost 3 |
| » Starters: Sam Jones vs Red Phillips | Eighth | 29 out |
| Sunday, August 5 |
| » Lost to Tigers (65-37), 7-0 | Tiger Stadium (2-8) | 36-68 | Lost 4 |
| » Starters: Ted Lyons vs Tommy Bridges | Eighth | 30 out |
| Tuesday, August 7 |
| » Defeated Indians (56-46), 8-2 | Comiskey Park I (22-30) | 37-68 | |
| » Starters: Mel Harder vs George Earnshaw | Eighth | 30 out |
| Wednesday, August 8 |
| » Lost to Indians (57-46), 11-4 | Comiskey Park I (22-31) | 37-69 | |
| » Starters: Monte Pearson vs Sam Jones | Eighth | 31 out |
| Friday, August 10 |
| » Lost to Browns (45-56), 8-2 | Comiskey Park I (22-32) | 37-70 | Lost 2 |
| » Starters: Bump Hadley vs Les Tietje | Eighth | 32½ out |
| Saturday, August 11 |
| » Lost to Browns (46-56), 9-8 | Comiskey Park I (22-33) | 37-71 | Lost 3 |
| » Starters: Dick Coffman vs Ted Lyons | Eighth | 33½ out |
| Sunday, August 12 |
| » Lost to Browns (47-56), 4-2 | Comiskey Park I (22-34) | 37-72 | Lost 4 |
| » Starters: George Blaeholder vs Sam Jones | Eighth | 34 out |
| » Defeated Browns (47-57), 3-2 | Comiskey Park I (23-34) | 38-72 | |
| » Starters: Bobo Newsom vs George Earnshaw | Eighth | 34 out |
| Wednesday, August 15 |
| » Lost to Athletics (43-61), 7-4 | Shibe Park (3-4) | 38-73 | |
| » Starters: Milt Gaston vs Sugar Cain | Eighth | 35½ out |
| » Lost to Athletics (44-61), 2-1 | Shibe Park (3-5) | 38-74 | Lost 2 |
| » Starters: Les Tietje vs Bill Dietrich | Eighth | 35½ out |
| Friday, August 17 |
| » Lost to Athletics (45-61), 9-8 | Shibe Park (3-6) | 38-75 | Lost 3 |
| » Starters: George Earnshaw vs Al Benton | Eighth | 35½ out |
| » Defeated Athletics (45-62), 3-2 | Shibe Park (4-6) | 39-75 | |
| » Starters: Ted Lyons vs Joe Cascarella | Eighth | 35½ out |
| Saturday, August 18 |
| » Defeated Senators (51-60), 4-3 | Griffith Stadium (2-7) | 40-75 | Won 2 |
| » Starters: Sam Jones vs Monte Weaver | Eighth | 35 out |
| » Lost to Senators (52-60), 4-1 | Griffith Stadium (2-8) | 40-76 | |
| » Starters: Harry Kinzy vs Jack Russell | Eighth | 35 out |
| Sunday, August 19 |
| » Defeated Senators (52-61), 9-8 | Griffith Stadium (3-8) | 41-76 | |
| » Starters: Milt Gaston vs Allen Benson | Eighth | 35½ out |
| » Major-league debuts: Allen Benson (Senators) |
| Wednesday, August 22 |
| » Lost to Red Sox (63-57), 3-2 | Fenway Park (2-6) | 41-77 | |
| » Starters: Les Tietje vs Wes Ferrell | Eighth | 36 out |
| Thursday, August 23 |
| » Defeated Red Sox (63-58), 7-2 | Fenway Park (3-6) | 42-77 | |
| » Starters: Ted Lyons vs Johnny Welch | Eighth | 35 out |
| Future White Sox Johnny Romano is born in Hoboken, NJ. |
| Saturday, August 25 |
| » Defeated Red Sox (63-59), 3-2 | Fenway Park (4-6) | 43-77 | Won 2 |
| » Starters: George Earnshaw vs Gordon Rhodes | Eighth | 35 out |
| » Defeated Red Sox (63-60), 8-7 | Fenway Park (5-6) | 44-77 | Won 3 |
| » Starters: Harry Kinzy vs Lefty Grove | Eighth | 35 out |
| Sunday, August 26 |
| » Lost to Yankees (75-47), 9-5 | Yankee Stadium (0-8) | 44-78 | |
| » Starters: Sam Jones vs Lefty Gomez | Seventh | 36½ out |
| » Lost to Yankees (76-47), 2-0 | Yankee Stadium (0-9) | 44-79 | Lost 2 |
| » Starters: Les Tietje vs Red Ruffing | Seventh | 36½ out |
| Monday, August 27 |
| » Lost to Yankees (77-47), 3-2 | Yankee Stadium (0-10) | 44-80 | Lost 3 |
| » Starters: Milt Gaston vs Jimmie DeShong | Eighth | 37½ out |
| Wednesday, August 29 |
| » Defeated Yankees (77-48), 3-1 | Yankee Stadium (1-10) | 45-80 | |
| » Starters: Ted Lyons vs Johnny Broaca | Eighth | 37 out |
| Friday, August 31 |
| » Lost to Browns (57-66), 3-2 | Sportsman's Park III (4-4) | 45-81 | |
| » Starters: Les Tietje vs George Blaeholder | Eighth | 38 out |
| Saturday, September 1 |
| » Tied Browns, 1-1 | Sportsman's Park III (4-4) | 45-81 | |
| » Starters: George Earnshaw vs Jack Knott | Eighth | 38½ out |
| Sunday, September 2 |
| » Lost to Browns (58-66), 4-2 | Sportsman's Park III (4-5) | 45-82 | Lost 2 |
| » Starters: Milt Gaston vs Bobo Newsom | Eighth | 39 out |
| » Lost to Browns (59-66), 5-4 | Sportsman's Park III (4-6) | 45-83 | Lost 3 |
| » Starters: Phil Gallivan vs Dick Coffman | Eighth | 39 out |
| Thursday, September 6 |
| » Lost to Yankees (81-51), 5-3 | Comiskey Park I (23-35) | 45-84 | Lost 4 |
| » Starters: Red Ruffing vs Ted Lyons | Eighth | 40 out |
| Friday, September 7 |
| » Defeated Yankees (81-52), 6-5 | Comiskey Park I (24-35) | 46-84 | |
| » Starters: Jimmie DeShong vs Les Tietje | Eighth | 38½ out |
| Saturday, September 8 |
| » Lost to Yankees (82-52), 7-1 | Comiskey Park I (24-36) | 46-85 | |
| » Starters: Johnny Broaca vs George Earnshaw | Eighth | 39 out |
| Sunday, September 9 |
| » Defeated Senators (59-73), 11-3 | Comiskey Park I (25-36) | 47-85 | |
| » Starters: Monte Weaver vs Milt Gaston | Eighth | 39½ out |
| » Lost to Senators (60-73), 2-1 | Comiskey Park I (25-37) | 47-86 | |
| » Starters: Alex McColl vs Phil Gallivan | Eighth | 39½ out |
| Monday, September 10 |
| » Lost to Senators (61-73), 7-4 | Comiskey Park I (25-38) | 47-87 | Lost 2 |
| » Starters: Jack Russell vs Hugo Klaerner | Seventh | 40½ out |
| Tuesday, September 11 |
| » Defeated Senators (61-74), 3-2 | Comiskey Park I (26-38) | 48-87 | |
| » Starters: Earl Whitehill vs Ted Lyons | Eighth | 39½ out |
| Friday, September 14 |
| » Defeated Red Sox (70-69), 1-0 | Comiskey Park I (27-38) | 49-87 | Won 2 |
| » Starters: Wes Ferrell vs Milt Gaston | Eighth | 39½ out |
| » Major-league debuts: Skinny Graham (Red Sox) |
| Sunday, September 16 |
| » Defeated Red Sox (70-70), 2-1 | Comiskey Park I (28-38) | 50-87 | Won 3 |
| » Starters: Johnny Welch vs George Earnshaw | Eighth | 39½ out |
| » Defeated Red Sox (70-71), 12-10 | Comiskey Park I (29-38) | 51-87 | Won 4 |
| » Starters: Gordon Rhodes vs Les Tietje | Eighth | 39½ out |
| Monday, September 17 |
| » Lost to Athletics (61-78), 9-4 | Comiskey Park I (29-39) | 51-88 | |
| » Starters: Joe Cascarella vs Hugo Klaerner | Eighth | 40½ out |
| » Major-league debuts: Rip Radcliff (White Sox) |
| Tuesday, September 18 |
| » Lost to Athletics (62-78), 6-0 | Comiskey Park I (29-40) | 51-89 | Lost 2 |
| » Starters: Bill Dietrich vs Vern Kennedy | Eighth | 41½ out |
| » Major-league debuts: Vern Kennedy (White Sox) |
| Wednesday, September 19 |
| » Lost to Athletics (63-78), 5-3 | Comiskey Park I (29-41) | 51-90 | Lost 3 |
| » Starters: George Caster vs Milt Gaston | Eighth | 42 out |
| » Lost to Athletics (64-78), 14-0 | Comiskey Park I (29-42) | 51-91 | Lost 4 |
| » Starters: Joe Cascarella vs Ted Lyons | Eighth | 42 out |
| Thursday, September 20 |
| » Lost to Athletics (65-78), 6-5 | Comiskey Park I (29-43) | 51-92 | Lost 5 |
| » Starters: Johnny Marcum vs George Earnshaw | Eighth | 42 out |
| Saturday, September 22 |
| » Lost to Indians (80-67), 9-8 | Comiskey Park I (29-44) | 51-93 | Lost 6 |
| » Starters: Oral Hildebrand vs Hugo Klaerner | Eighth | 43½ out |
| Sunday, September 23 |
| » Lost to Indians (81-67), 2-1 | Comiskey Park I (29-45) | 51-94 | Lost 7 |
| » Starters: Monte Pearson vs Vern Kennedy | Eighth | 44½ out |
| » Lost to Indians (82-67), 5-1 | Comiskey Park I (29-46) | 51-95 | Lost 8 |
| » Starters: Ralph Winegarner vs Les Tietje | Eighth | 44½ out |
| Wednesday, September 26 |
| » Lost to Tigers (98-52), 12-10 | Tiger Stadium (2-9) | 51-96 | Lost 9 |
| » Starters: Ted Lyons vs Tommy Bridges | Eighth | 46½ out |
| » Lost to Tigers (99-52), 10-3 | Tiger Stadium (2-10) | 51-97 | Lost 10 |
| » Starters: Milt Gaston vs Elden Auker | Eighth | 46½ out |
| Thursday, September 27 |
| » Defeated Tigers (99-53), 11-0 | Tiger Stadium (3-10) | 52-97 | |
| » Starters: George Earnshaw vs Schoolboy Rowe | Eighth | 45½ out |
| Saturday, September 29 |
| » Lost to Indians (84-68), 4-0 | League Park II (3-4) | 52-98 | |
| » Starters: Les Tietje vs Mel Harder | Eighth | 46 out |
| Sunday, September 30 |
| » Defeated Indians (84-69), 9-5 | Cleveland Stadium (1-2) | 53-98 | |
| » Starters: Ted Lyons vs Bill Perrin | Eighth | 47 out |
| » Lost to Indians (85-69), 5-3 | Cleveland Stadium (1-3) | 53-99 | |
| » Starters: Vern Kennedy vs Ralph Winegarner | Eighth | 47 out |
| Thursday, October 4 |
| Former White Sox Nixey Callahan dies in Boston, MA at the age of 61. |
| Saturday, November 10 |
| Future White Sox Norm Cash is born in Justiceburg, TX. |
| Thursday, November 15 |
| Former White Sox Barney Reilly dies in St.Joseph, MO at the age of 50. |
| Tuesday, December 11 |
| Future White Sox Lee Maye is born in Tuscaloosa, AL. |
| Saturday, December 29 |
| Future White Sox Ramon Conde is born in Juana Diaz, P.R. |
Game information provided by Retrosheet (www.retrosheet.org) |
