| Saturday, January 20 |
| Future Senator Camilo Pascual is born in Havana, Cuba. Future Senator Camilo Pascual is born in Havana, Cuba. |
| Saturday, February 17 |
| Future Senator Willie Kirkland is born in Siluria, AL. |
| Thursday, March 8 |
| Future Senator Marv Breeding is born in Decatur, AL. |
| Tuesday, April 17 |
| » Defeated Red Sox (0-1), 6-5 | Fenway Park (1-0) | 1-0 | |
| » Starters: Earl Whitehill vs Gordon Rhodes | First | -- |
| » Major-league debuts: Moose Solters (Red Sox) |
| Wednesday, April 18 |
| » Defeated Red Sox (0-2), 5-4 | Fenway Park (2-0) | 2-0 | Won 2 |
| » Starters: Monte Weaver vs Bob Weiland | First | -- |
| Thursday, April 19 |
| » Lost to Red Sox (1-2), 5-4 | Fenway Park (2-1) | 2-1 | |
| » Starters: Lefty Stewart vs Rube Walberg | Second | ½ out |
| » Lost to Red Sox (2-2), 7-3 | Fenway Park (2-2) | 2-2 | Lost 2 |
| » Starters: Ray Prim vs Johnny Welch | Second | ½ out |
| Former Senator Piano Legs Hickman dies in Morgantown, WV at the age of 59. |
| Friday, April 20 |
| » Lost to Athletics (2-2), 9-6 | Shibe Park (0-1) | 2-3 | Lost 3 |
| » Starters: Monte Weaver vs Johnny Marcum | Fourth | 1½ out |
| Saturday, April 21 |
| » Lost to Athletics (3-2), 7-2 | Shibe Park (0-2) | 2-4 | Lost 4 |
| » Starters: Earl Whitehill vs Sugar Cain | Fifth | 2 out |
| Sunday, April 22 |
| » Defeated Athletics (3-3), 4-3 | Shibe Park (1-2) | 3-4 | |
| » Starters: Tommy Thomas vs Roy Mahaffey | Fifth | 1½ out |
| Tuesday, April 24 |
| » Lost to Red Sox (4-3), 5-0 | Griffith Stadium (0-1) | 3-5 | |
| » Starters: Johnny Welch vs Lefty Stewart | Seventh | 2½ out |
| Thursday, April 26 |
| » Defeated Red Sox (4-4), 10-7 | Griffith Stadium (1-1) | 4-5 | |
| » Starters: Bob Weiland vs Monte Weaver | Fifth | 2 out |
| Saturday, April 28 |
| » Defeated Athletics (4-6), 7-6 | Griffith Stadium (2-1) | 5-5 | Won 2 |
| » Starters: Sugar Cain vs Tommy Thomas | Fourth | 2 out |
| Sunday, April 29 |
| » Defeated Athletics (4-7), 7-6 | Griffith Stadium (3-1) | 6-5 | Won 3 |
| » Starters: Johnny Marcum vs Alvin Crowder | Fourth | 1 out |
| Monday, April 30 |
| » Lost to Yankees (7-4), 7-4 | Griffith Stadium (3-2) | 6-6 | |
| » Starters: Red Ruffing vs Earl Whitehill | Fourth | 1½ out |
| Future Senator Ken Retzer is born in Wood River, IL. |
| Tuesday, May 1 |
| » Lost to Yankees (8-4), 10-5 | Griffith Stadium (3-3) | 6-7 | Lost 2 |
| » Starters: Danny MacFayden vs Lefty Stewart | Fifth | 2½ out |
| Wednesday, May 2 |
| » Defeated Yankees (8-5), 6-2 | Griffith Stadium (4-3) | 7-7 | |
| » Starters: Russ VanAtta vs Monte Weaver | Fourth | 1½ out |
| Thursday, May 3 |
| Future Senator Chuck Hinton is born in Rocky Mount, NC. |
| Friday, May 4 |
| » Lost to Indians (7-4), 5-3 | Griffith Stadium (4-4) | 7-8 | |
| » Starters: Lloyd Brown vs Earl Whitehill | Fifth | 2½ out |
| Saturday, May 5 |
| » Defeated Indians (7-5), 9-1 | Griffith Stadium (5-4) | 8-8 | |
| » Starters: Oral Hildebrand vs Lefty Stewart | Fifth | 2½ out |
| Sunday, May 6 |
| » Defeated White Sox (4-9), 5-0 | Griffith Stadium (6-4) | 9-8 | Won 2 |
| » Starters: Sam Jones vs Tommy Thomas | Fourth | 2½ out |
| Monday, May 7 |
| » Defeated White Sox (4-10), 17-7 | Griffith Stadium (7-4) | 10-8 | Won 3 |
| » Starters: Joe Heving vs Monte Weaver | Third | 2½ out |
| Tuesday, May 8 |
| » Defeated White Sox (4-11), 7-6 | Griffith Stadium (8-4) | 11-8 | Won 4 |
| » Starters: Phil Gallivan vs Earl Whitehill | Second | 2½ out |
| Wednesday, May 9 |
| » Lost to White Sox (5-11), 8-1 | Griffith Stadium (8-5) | 11-9 | |
| » Starters: Milt Gaston vs Bobby Burke | Second | 2½ out |
| Friday, May 11 |
| » Lost to Browns (7-11), 4-3 | Griffith Stadium (8-6) | 11-10 | Lost 2 |
| » Starters: Bump Hadley vs Lefty Stewart | Third | 4 out |
| Saturday, May 12 |
| » Lost to Browns (8-11), 6-5 | Griffith Stadium (8-7) | 11-11 | Lost 3 |
| » Starters: George Blaeholder vs Monte Weaver | Fifth | 5½ out |
| » Lost to Browns (9-11), 2-1 | Griffith Stadium (8-8) | 11-12 | Lost 4 |
| » Starters: Jim Weaver vs Tommy Thomas | Fifth | 5½ out |
| Sunday, May 13 |
| » Defeated Tigers (11-11), 7-4 | Griffith Stadium (9-8) | 12-12 | |
| » Starters: Tommy Bridges vs Earl Whitehill | Fifth | 5½ out |
| Monday, May 14 |
| » Lost to Tigers (12-11), 5-0 | Griffith Stadium (9-9) | 12-13 | |
| » Starters: Vic Sorrell vs Alvin Crowder | Fourth | 6 out |
| Thursday, May 17 |
| » Lost to Indians (12-9), 14-6 | League Park II (0-1) | 12-14 | Lost 2 |
| » Starters: Earl Whitehill vs Monte Pearson | Fifth | 6 out |
| Friday, May 18 |
| » Defeated Indians (12-10), 3-1 | League Park II (1-1) | 13-14 | |
| » Starters: Lefty Stewart vs Lloyd Brown | Fourth | 5 out |
| Saturday, May 19 |
| » Defeated Indians (12-11), 3-2 | League Park II (2-1) | 14-14 | Won 2 |
| » Starters: Monte Weaver vs Mel Harder | Fourth | 5 out |
| Sunday, May 20 |
| » Defeated Tigers (14-13), 4-1 | Tiger Stadium (1-0) | 15-14 | Won 3 |
| » Starters: Bobby Burke vs Schoolboy Rowe | Fourth | 4 out |
| Monday, May 21 |
| » Lost to Tigers (15-13), 6-5 | Tiger Stadium (1-1) | 15-15 | |
| » Starters: Earl Whitehill vs Firpo Marberry | Fourth | 4 out |
| Tuesday, May 22 |
| » Defeated Tigers (15-14), 5-2 | Tiger Stadium (2-1) | 16-15 | |
| » Starters: Alvin Crowder vs Tommy Bridges | Fourth | 3 out |
| Future Senator Jose Valdivielso is born in Matanzas, Cuba. |
| Wednesday, May 23 |
| » Lost to Browns (14-14), 6-2 | Sportsman's Park III (0-1) | 16-16 | |
| » Starters: Lefty Stewart vs Bobo Newsom | Fifth | 3 out |
| Thursday, May 24 |
| » Lost to Browns (15-14), 6-5 | Sportsman's Park III (0-2) | 16-17 | Lost 2 |
| » Starters: Monte Weaver vs Dick Coffman | Fifth | 4 out |
| Friday, May 25 |
| » Defeated Browns (15-15), 9-3 | Sportsman's Park III (1-2) | 17-17 | |
| » Starters: Earl Whitehill vs George Blaeholder | Fifth | 3 out |
| Saturday, May 26 |
| » Defeated White Sox (12-19), 9-7 | Comiskey Park I (1-0) | 18-17 | Won 2 |
| » Starters: Alvin Crowder vs Phil Gallivan | Fourth | 3 out |
| Future Senator Jim Mahoney is born in Englewood, NJ. |
| Sunday, May 27 |
| » Defeated White Sox (12-20), 9-6 | Comiskey Park I (2-0) | 19-17 | Won 3 |
| » Starters: Monte Weaver vs Sam Jones | Fourth | 3 out |
| Monday, May 28 |
| » Lost to White Sox (13-20), 11-7 | Comiskey Park I (2-1) | 19-18 | |
| » Starters: Tommy Thomas vs Ted Lyons | Fourth | 3 out |
| Wednesday, May 30 |
| » Defeated Yankees (21-15), 1-0 | Yankee Stadium (1-0) | 20-18 | |
| » Starters: Earl Whitehill vs Lefty Gomez | Fourth | 3½ out |
| » Lost to Yankees (22-15), 5-4 | Yankee Stadium (1-1) | 20-19 | |
| » Starters: Lefty Stewart vs Johnny Murphy | Fourth | 3½ out |
| Thursday, May 31 |
| » Defeated Yankees (22-16), 9-3 | Yankee Stadium (2-1) | 21-19 | |
| » Starters: Monte Weaver vs Russ VanAtta | Fourth | 2½ out |
| Friday, June 1 |
| » Lost to Red Sox (18-21), 13-1 | Griffith Stadium (9-10) | 21-20 | |
| » Starters: Herb Pennock vs Alvin Crowder | Fourth | 3 out |
| Saturday, June 2 |
| » Defeated Red Sox (18-22), 2-1 | Griffith Stadium (10-10) | 22-20 | |
| » Starters: Lefty Grove vs Tommy Thomas | Fourth | 3½ out |
| » Lost to Red Sox (19-22), 10-7 | Griffith Stadium (10-11) | 22-21 | |
| » Starters: Johnny Welch vs Bobby Burke | Fourth | 3½ out |
| Sunday, June 3 |
| » Lost to Red Sox (20-22), 7-2 | Griffith Stadium (10-12) | 22-22 | Lost 2 |
| » Starters: Fritz Ostermueller vs Earl Whitehill | Fifth | 3½ out |
| Tuesday, June 5 |
| » Lost to Athletics (18-24), 8-7 | Griffith Stadium (10-13) | 22-23 | Lost 3 |
| » Starters: Al Benton vs Alvin Crowder | Fifth | 3 out |
| » Defeated Athletics (18-25), 4-3 | Griffith Stadium (11-13) | 23-23 | |
| » Starters: Joe Cascarella vs Monte Weaver | Fifth | 3 out |
| Thursday, June 7 |
| » Defeated Athletics (18-26), 7-3 | Griffith Stadium (12-13) | 24-23 | Won 2 |
| » Starters: Sugar Cain vs Earl Whitehill | Fifth | 3½ out |
| Friday, June 8 |
| » Lost to Red Sox (23-23), 3-2 | Fenway Park (2-3) | 24-24 | |
| » Starters: Jack Russell vs Fritz Ostermueller | Sixth | 4½ out |
| Saturday, June 9 |
| » Defeated Red Sox (23-24), 8-1 | Fenway Park (3-3) | 25-24 | |
| » Starters: Monte Weaver vs Lefty Grove | Fifth | 4½ out |
| Sunday, June 10 |
| » Lost to Red Sox (24-24), 4-3 | Fenway Park (3-4) | 25-25 | |
| » Starters: Tommy Thomas vs Wes Ferrell | Sixth | 4½ out |
| Wednesday, June 13 |
| » Defeated White Sox (17-31), 11-3 | Griffith Stadium (13-13) | 26-25 | |
| » Starters: Ted Lyons vs Earl Whitehill | Fourth | 3½ out |
| » Defeated White Sox (17-32), 13-11 | Griffith Stadium (14-13) | 27-25 | Won 2 |
| » Starters: Milt Gaston vs Jack Russell | Fourth | 3½ out |
| Thursday, June 14 |
| » Defeated White Sox (17-33), 5-1 | Griffith Stadium (15-13) | 28-25 | Won 3 |
| » Starters: George Earnshaw vs Monte Weaver | Fourth | 3 out |
| Friday, June 15 |
| » Defeated White Sox (17-34), 8-7 | Griffith Stadium (16-13) | 29-25 | Won 4 |
| » Starters: Sam Jones vs Alvin Crowder | Fourth | 3 out |
| Saturday, June 16 |
| » Defeated Indians (26-22), 7-1 | Griffith Stadium (17-13) | 30-25 | Won 5 |
| » Starters: Bob Weiland vs Tommy Thomas | Third | 2½ out |
| » Defeated Indians (26-23), 5-3 | Griffith Stadium (18-13) | 31-25 | Won 6 |
| » Starters: Lloyd Brown vs Bobby Burke | Third | 2½ out |
| Sunday, June 17 |
| » Lost to Indians (27-23), 8-5 | Griffith Stadium (18-14) | 31-26 | |
| » Starters: Monte Pearson vs Earl Whitehill | Third | 3 out |
| Tuesday, June 19 |
| » Defeated Indians (27-24), 6-2 | Griffith Stadium (19-14) | 32-26 | |
| » Starters: Oral Hildebrand vs Lefty Stewart | Third | 2½ out |
| » Lost to Indians (28-24), 3-0 | Griffith Stadium (19-15) | 32-27 | |
| » Starters: Mel Harder vs Monte Weaver | Third | 2½ out |
| Wednesday, June 20 |
| » Lost to Tigers (34-23), 13-10 | Griffith Stadium (19-16) | 32-28 | Lost 2 |
| » Starters: Schoolboy Rowe vs Alvin Crowder | Third | 4 out |
| Thursday, June 21 |
| » Defeated Tigers (34-24), 8-6 | Griffith Stadium (20-16) | 33-28 | |
| » Starters: Tommy Bridges vs Earl Whitehill | Third | 3 out |
| Friday, June 22 |
| » Lost to Tigers (35-24), 11-3 | Griffith Stadium (20-17) | 33-29 | |
| » Starters: Carl Fischer vs Bobby Burke | Fifth | 3½ out |
| Saturday, June 23 |
| » Lost to Tigers (36-24), 9-6 | Griffith Stadium (20-18) | 33-30 | Lost 2 |
| » Starters: Vic Sorrell vs Tommy Thomas | Fifth | 5½ out |
| » Lost to Tigers (37-24), 8-6 | Griffith Stadium (20-19) | 33-31 | Lost 3 |
| » Starters: Firpo Marberry vs Monte Weaver | Fifth | 5½ out |
| Sunday, June 24 |
| » Defeated Browns (28-32), 7-0 | Griffith Stadium (21-19) | 34-31 | |
| » Starters: Bobo Newsom vs Lefty Stewart | Fifth | 5½ out |
| Monday, June 25 |
| » Defeated Browns (28-33), 6-4 | Griffith Stadium (22-19) | 35-31 | Won 2 |
| » Starters: Dick Coffman vs Earl Whitehill | Fourth | 4½ out |
| Tuesday, June 26 |
| » Defeated Browns (28-34), 10-9 | Griffith Stadium (23-19) | 36-31 | Won 3 |
| » Starters: Bump Hadley vs Bobby Burke | Third | 4½ out |
| Wednesday, June 27 |
| Future Senator Ed Hobaugh is born in Kittanning, PA. |
| Thursday, June 28 |
| » Lost to Yankees (40-24), 4-0 | Griffith Stadium (23-20) | 36-32 | |
| » Starters: Red Ruffing vs Monte Weaver | Fourth | 6 out |
| Sunday, July 1 |
| » Lost to Yankees (41-24), 5-2 | Griffith Stadium (23-21) | 36-33 | Lost 2 |
| » Starters: Johnny Broaca vs Earl Whitehill | Fifth | 7 out |
| Monday, July 2 |
| » Defeated Athletics (27-40), 7-3 | Shibe Park (2-2) | 37-33 | |
| » Starters: Tommy Thomas vs Bill Dietrich | Third | 7 out |
| Tuesday, July 3 |
| » Defeated Athletics (27-41), 12-6 | Shibe Park (3-2) | 38-33 | Won 2 |
| » Starters: Monte Weaver vs Sugar Cain | Third | 6 out |
| Wednesday, July 4 |
| » Lost to Athletics (28-41), 10-9 | Griffith Stadium (23-22) | 38-34 | |
| » Starters: Al Benton vs Alvin Crowder | Fourth | 7 out |
| » Lost to Athletics (29-41), 6-3 | Griffith Stadium (23-23) | 38-35 | Lost 2 |
| » Starters: Johnny Marcum vs Bobby Burke | Fourth | 7 out |
| Thursday, July 5 |
| » Lost to Yankees (44-26), 8-3 | Yankee Stadium (2-2) | 38-36 | Lost 3 |
| » Starters: Lefty Stewart vs Johnny Broaca | Fifth | 8 out |
| Friday, July 6 |
| » Defeated Yankees (44-27), 9-8 | Yankee Stadium (3-2) | 39-36 | |
| » Starters: Earl Whitehill vs Red Ruffing | Fourth | 7 out |
| Former Senator Ray Francis dies in Atlanta, GA at the age of 42. |
| Saturday, July 7 |
| » Lost to Yankees (45-27), 7-4 | Yankee Stadium (3-3) | 39-37 | |
| » Starters: Alvin Crowder vs Lefty Gomez | Fifth | 8 out |
| Sunday, July 8 |
| » Lost to Yankees (46-27), 6-3 | Yankee Stadium (3-4) | 39-38 | Lost 2 |
| » Starters: Monte Weaver vs Jimmie DeShong | Fifth | 9 out |
| Wednesday, July 11 |
| » Lost to Tigers (48-29), 13-7 | Tiger Stadium (2-2) | 39-39 | Lost 3 |
| » Starters: Tommy Thomas vs Luke Hamlin | Fifth | 10 out |
| Future Senator Bob Allison is born in Raytown, MO. |
| Friday, July 13 |
| » Defeated Indians (39-37), 3-2 | League Park II (3-1) | 40-39 | |
| » Starters: Lefty Stewart vs Oral Hildebrand | Fifth | 9½ out |
| Future Senator Ken Hunt is born in Grand Forks, ND. |
| Saturday, July 14 |
| » Lost to Indians (40-37), 2-0 | League Park II (3-2) | 40-40 | |
| » Starters: Earl Whitehill vs Mel Harder | Fifth | 10 out |
| Sunday, July 15 |
| » Lost to Indians (41-37), 10-8 | Cleveland Stadium (0-1) | 40-41 | Lost 2 |
| » Starters: Monte Weaver vs Willis Hudlin | Fifth | 11½ out |
| » Lost to Indians (42-37), 10-8 | Cleveland Stadium (0-2) | 40-42 | Lost 3 |
| » Starters: Tommy Thomas vs Monte Pearson | Fifth | 11½ out |
| Monday, July 16 |
| » Defeated Tigers (51-31), 10-8 | Tiger Stadium (3-2) | 41-42 | |
| » Starters: Alvin Crowder vs Luke Hamlin | Fifth | 10½ out |
| Tuesday, July 17 |
| » Lost to Tigers (52-31), 4-3 | Tiger Stadium (3-3) | 41-43 | |
| » Starters: Lefty Stewart vs Carl Fischer | Fifth | 11½ out |
| Wednesday, July 18 |
| » Lost to Tigers (53-31), 4-2 | Tiger Stadium (3-4) | 41-44 | Lost 2 |
| » Starters: Earl Whitehill vs Tommy Bridges | Fifth | 12½ out |
| Thursday, July 19 |
| » Lost to Browns (37-41), 8-7 | Sportsman's Park III (1-3) | 41-45 | Lost 3 |
| » Starters: Monte Weaver vs Ed Wells | Fifth | 13 out |
| Friday, July 20 |
| » Lost to Browns (38-41), 7-4 | Sportsman's Park III (1-4) | 41-46 | Lost 4 |
| » Starters: Alvin Crowder vs George Blaeholder | Sixth | 13 out |
| Saturday, July 21 |
| » Lost to Browns (39-41), 6-5 | Sportsman's Park III (1-5) | 41-47 | Lost 5 |
| » Starters: Bobby Burke vs Bobo Newsom | Sixth | 14 out |
| Sunday, July 22 |
| » Defeated Browns (39-42), 6-4 | Sportsman's Park III (2-5) | 42-47 | |
| » Starters: Ed Linke vs Jack Knott | Sixth | 13½ out |
| Monday, July 23 |
| » Defeated White Sox (29-61), 11-5 | Comiskey Park I (3-1) | 43-47 | Won 2 |
| » Starters: Earl Whitehill vs Milt Gaston | Fifth | 13½ out |
| Tuesday, July 24 |
| » Lost to White Sox (30-61), 4-1 | Comiskey Park I (3-2) | 43-48 | |
| » Starters: Alvin Crowder vs Les Tietje | Sixth | 14½ out |
| Wednesday, July 25 |
| » Lost to White Sox (31-61), 4-0 | Comiskey Park I (3-3) | 43-49 | Lost 2 |
| » Starters: Lefty Stewart vs George Earnshaw | Sixth | 14½ out |
| Thursday, July 26 |
| » Lost to White Sox (32-61), 9-0 | Comiskey Park I (3-4) | 43-50 | Lost 3 |
| » Starters: Monte Weaver vs Sam Jones | Sixth | 14½ out |
| Saturday, July 28 |
| » Lost to Red Sox (51-44), 6-3 | Griffith Stadium (23-24) | 43-51 | Lost 4 |
| » Starters: Fritz Ostermueller vs Earl Whitehill | Sixth | 15 out |
| » Defeated Red Sox (51-45), 2-1 | Griffith Stadium (24-24) | 44-51 | |
| » Starters: Gordon Rhodes vs Tommy Thomas | Sixth | 15 out |
| Monday, July 30 |
| » Lost to Red Sox (52-45), 8-0 | Griffith Stadium (24-25) | 44-52 | |
| » Starters: Wes Ferrell vs Ed Linke | Sixth | 15½ out |
| Tuesday, July 31 |
| » Lost to Athletics (38-55), 8-2 | Shibe Park (3-3) | 44-53 | Lost 2 |
| » Starters: Alex McColl vs Johnny Marcum | Sixth | 16 out |
| Wednesday, August 1 |
| » Defeated Athletics (38-56), 11-7 | Shibe Park (4-3) | 45-53 | |
| » Starters: Monte Weaver vs Mort Flohr | Fifth | 16 out |
| Saturday, August 4 |
| » Defeated Red Sox (53-49), 7-5 | Fenway Park (4-4) | 46-53 | Won 2 |
| » Starters: Earl Whitehill vs Wes Ferrell | Fifth | 17 out |
| Future Senator Dallas Green is born in Newport, DE. |
| Sunday, August 5 |
| » Defeated Red Sox (53-50), 2-1 | Fenway Park (5-4) | 47-53 | Won 3 |
| » Starters: Ed Linke vs Fritz Ostermueller | Fifth | 17½ out |
| » Lost to Red Sox (54-50), 7-3 | Fenway Park (5-5) | 47-54 | |
| » Starters: Tommy Thomas vs Gordon Rhodes | Fifth | 17½ out |
| Tuesday, August 7 |
| » Lost to Yankees (64-37), 4-3 | Griffith Stadium (24-26) | 47-55 | Lost 2 |
| » Starters: Johnny Murphy vs Monte Weaver | Fifth | 18 out |
| » Defeated Yankees (64-38), 6-3 | Griffith Stadium (25-26) | 48-55 | |
| » Starters: Johnny Broaca vs Lefty Stewart | Fifth | 18 out |
| Wednesday, August 8 |
| » Defeated Yankees (64-39), 9-2 | Griffith Stadium (26-26) | 49-55 | Won 2 |
| » Starters: Red Ruffing vs Earl Whitehill | Fifth | 18 out |
| Friday, August 10 |
| » Lost to Athletics (40-61), 8-6 | Griffith Stadium (26-27) | 49-56 | |
| » Starters: Bill Dietrich vs Ed Linke | Fifth | 19½ out |
| Saturday, August 11 |
| » Lost to Athletics (41-61), 2-1 | Griffith Stadium (26-28) | 49-57 | Lost 2 |
| » Starters: Al Benton vs Monte Weaver | Fifth | 20½ out |
| Sunday, August 12 |
| » Tied Athletics, 1-1 | Griffith Stadium (26-28) | 49-57 | |
| » Starters: Joe Cascarella vs Earl Whitehill | Fifth | 21 out |
| Monday, August 13 |
| » Lost to Athletics (42-61), 9-0 | Griffith Stadium (26-29) | 49-58 | Lost 3 |
| » Starters: Johnny Marcum vs Tommy Thomas | Fifth | 21½ out |
| Tuesday, August 14 |
| » Lost to Indians (58-49), 5-1 | Griffith Stadium (26-30) | 49-59 | Lost 4 |
| » Starters: Mel Harder vs Lefty Stewart | Fifth | 23 out |
| Friday, August 17 |
| » Defeated Indians (58-50), 4-3 | Griffith Stadium (27-30) | 50-59 | |
| » Starters: Oral Hildebrand vs Earl Whitehill | Fifth | 21½ out |
| » Defeated Indians (58-51), 1-0 | Griffith Stadium (28-30) | 51-59 | Won 2 |
| » Starters: Monte Pearson vs Bobby Burke | Fifth | 21½ out |
| Saturday, August 18 |
| » Lost to White Sox (40-75), 4-3 | Griffith Stadium (28-31) | 51-60 | |
| » Starters: Sam Jones vs Monte Weaver | Fifth | 21 out |
| » Defeated White Sox (40-76), 4-1 | Griffith Stadium (29-31) | 52-60 | |
| » Starters: Harry Kinzy vs Jack Russell | Fifth | 21 out |
| Future Senator Billy Consolo is born in Cleveland, OH. |
| Sunday, August 19 |
| » Lost to White Sox (41-76), 9-8 | Griffith Stadium (29-32) | 52-61 | |
| » Starters: Milt Gaston vs Allen Benson | Fifth | 22½ out |
| » Major-league debuts: Allen Benson (Senators) |
| Wednesday, August 22 |
| » Defeated Tigers (77-41), 7-5 | Griffith Stadium (30-32) | 53-61 | |
| » Starters: Vic Sorrell vs Earl Whitehill | Fifth | 22 out |
| » Major-league debuts: Rudy York (Tigers) |
| Thursday, August 23 |
| » Defeated Tigers (77-42), 3-1 | Griffith Stadium (31-32) | 54-61 | Won 2 |
| » Starters: Tommy Bridges vs Bobby Burke | Fifth | 21 out |
| Friday, August 24 |
| » Lost to Tigers (78-42), 12-6 | Griffith Stadium (31-33) | 54-62 | |
| » Starters: Elden Auker vs Lefty Stewart | Fifth | 22 out |
| Saturday, August 25 |
| » Lost to Tigers (79-42), 4-2 | Griffith Stadium (31-34) | 54-63 | Lost 2 |
| » Starters: Schoolboy Rowe vs Monte Weaver | Fifth | 23 out |
| Sunday, August 26 |
| » Lost to Browns (53-65), 3-0 | Griffith Stadium (31-35) | 54-64 | Lost 3 |
| » Starters: George Blaeholder vs Tommy Thomas | Fifth | 24½ out |
| » Lost to Browns (54-65), 9-5 | Griffith Stadium (31-36) | 54-65 | Lost 4 |
| » Starters: Jack Knott vs Allen Benson | Fifth | 24½ out |
| Monday, August 27 |
| » Defeated Browns (54-66), 6-1 | Griffith Stadium (32-36) | 55-65 | |
| » Starters: Bump Hadley vs Jack Russell | Fifth | 24½ out |
| Tuesday, August 28 |
| » Lost to Browns (55-66), 4-0 | Griffith Stadium (32-37) | 55-66 | |
| » Starters: Bobo Newsom vs Bobby Burke | Fifth | 25 out |
| Wednesday, August 29 |
| » Lost to Browns (56-66), 5-4 | Griffith Stadium (32-38) | 55-67 | Lost 2 |
| » Starters: Dick Coffman vs Earl Whitehill | Sixth | 25½ out |
| Thursday, August 30 |
| » Lost to Yankees (78-48), 8-2 | Yankee Stadium (3-5) | 55-68 | Lost 3 |
| » Starters: Monte Weaver vs Lefty Gomez | Sixth | 26½ out |
| Friday, August 31 |
| » Lost to Yankees (79-48), 3-1 | Yankee Stadium (3-6) | 55-69 | Lost 4 |
| » Starters: Jack Russell vs Red Ruffing | Sixth | 27 out |
| Saturday, September 1 |
| » Defeated Yankees (79-49), 5-1 | Yankee Stadium (4-6) | 56-69 | |
| » Starters: Lefty Stewart vs Jimmie DeShong | Sixth | 27 out |
| Sunday, September 2 |
| » Defeated Yankees (79-50), 9-3 | Yankee Stadium (5-6) | 57-69 | Won 2 |
| » Starters: Earl Whitehill vs Johnny Murphy | Sixth | 26 out |
| Monday, September 3 |
| » Lost to Red Sox (67-63), 6-3 | Griffith Stadium (32-39) | 57-70 | |
| » Starters: Wes Ferrell vs Monte Weaver | Sixth | 26½ out |
| » Tied Red Sox, 4-4 | Griffith Stadium (32-39) | 57-70 | |
| » Starters: Rube Walberg vs Tommy Thomas | Sixth | 26½ out |
| Wednesday, September 5 |
| » Lost to Browns (60-69), 6-4 | Sportsman's Park III (2-6) | 57-71 | Lost 2 |
| » Starters: Jack Russell vs Bobo Newsom | Sixth | 27½ out |
| Friday, September 7 |
| » Defeated Browns (60-70), 7-4 | Sportsman's Park III (3-6) | 58-71 | |
| » Starters: Earl Whitehill vs George Blaeholder | Sixth | 26½ out |
| » Lost to Browns (61-70), 3-2 | Sportsman's Park III (3-7) | 58-72 | |
| » Starters: Lefty Stewart vs Dick Coffman | Sixth | 26½ out |
| Saturday, September 8 |
| » Defeated Browns (61-71), 5-1 | Sportsman's Park III (4-7) | 59-72 | |
| » Starters: Bobby Burke vs Bump Hadley | Sixth | 26 out |
| Sunday, September 9 |
| » Lost to White Sox (47-85), 11-3 | Comiskey Park I (3-5) | 59-73 | |
| » Starters: Monte Weaver vs Milt Gaston | Sixth | 26½ out |
| » Defeated White Sox (47-86), 2-1 | Comiskey Park I (4-5) | 60-73 | |
| » Starters: Alex McColl vs Phil Gallivan | Sixth | 26½ out |
| Monday, September 10 |
| » Defeated White Sox (47-87), 7-4 | Comiskey Park I (5-5) | 61-73 | Won 2 |
| » Starters: Jack Russell vs Hugo Klaerner | Fifth | 26½ out |
| Tuesday, September 11 |
| » Lost to White Sox (48-87), 3-2 | Comiskey Park I (5-6) | 61-74 | |
| » Starters: Earl Whitehill vs Ted Lyons | Sixth | 26½ out |
| Wednesday, September 12 |
| Future Senator Albie Pearson is born in Alhambra, CA. |
| Thursday, September 13 |
| » Lost to Tigers (89-49), 2-0 | Tiger Stadium (3-5) | 61-75 | Lost 2 |
| » Starters: Lefty Stewart vs Schoolboy Rowe | Sixth | 27 out |
| Friday, September 14 |
| » Lost to Tigers (90-49), 6-4 | Tiger Stadium (3-6) | 61-76 | Lost 3 |
| » Starters: Bobby Burke vs Carl Fischer | Sixth | 28 out |
| Saturday, September 15 |
| » Lost to Tigers (91-49), 12-2 | Tiger Stadium (3-7) | 61-77 | Lost 4 |
| » Starters: Jack Russell vs Elden Auker | Sixth | 29 out |
| Sunday, September 16 |
| » Lost to Tigers (92-49), 2-1 | Tiger Stadium (3-8) | 61-78 | Lost 5 |
| » Starters: Monte Weaver vs Tommy Bridges | Sixth | 30 out |
| Monday, September 17 |
| » Defeated Indians (76-66), 13-6 | League Park II (4-2) | 62-78 | |
| » Starters: Reese Diggs vs Oral Hildebrand | Sixth | 30 out |
| Tuesday, September 18 |
| » Lost to Indians (77-66), 5-4 | League Park II (4-3) | 62-79 | |
| » Starters: Lefty Stewart vs Thornton Lee | Seventh | 31½ out |
| » Lost to Indians (78-66), 9-6 | League Park II (4-4) | 62-80 | Lost 2 |
| » Starters: Tommy Thomas vs Lloyd Brown | Seventh | 31½ out |
| » Major-league debuts: Syd Cohen (Senators) |
| Wednesday, September 19 |
| » Defeated Indians (78-67), 5-2 | League Park II (5-4) | 63-80 | |
| » Starters: Bobby Burke vs Monte Pearson | Seventh | 30½ out |
| Thursday, September 20 |
| » Lost to Indians (79-67), 6-1 | League Park II (5-5) | 63-81 | |
| » Starters: Syd Cohen vs Mel Harder | Seventh | 30½ out |
| Sunday, September 23 |
| » Defeated Athletics (65-79), 2-1 | Shibe Park (5-3) | 64-81 | |
| » Starters: Monte Weaver vs Sugar Cain | Seventh | 31 out |
| » Tied Athletics, 5-5 | Shibe Park (5-3) | 64-81 | |
| » Starters: Jack Russell vs Bill Dietrich | Seventh | 31 out |
| Monday, September 24 |
| » Lost to Athletics (66-79), 5-4 | Shibe Park (5-4) | 64-82 | |
| » Starters: Reese Diggs vs Johnny Marcum | Seventh | 32 out |
| » Lost to Athletics (67-79), 3-0 | Shibe Park (5-5) | 64-83 | Lost 2 |
| » Starters: Orville Armbrust vs Bill Dietrich | Seventh | 32 out |
| Tuesday, September 25 |
| » Lost to Red Sox (74-75), 1-0 | Fenway Park (5-6) | 64-84 | Lost 3 |
| » Starters: Bobby Burke vs Wes Ferrell | Seventh | 33 out |
| » Lost to Red Sox (75-75), 9-3 | Fenway Park (5-7) | 64-85 | Lost 4 |
| » Starters: Lefty Stewart vs Johnny Welch | Seventh | 33 out |
| Saturday, September 29 |
| » Defeated Yankees (93-59), 8-5 | Griffith Stadium (33-39) | 65-85 | |
| » Starters: Johnny Broaca vs Syd Cohen | Seventh | 33½ out |
| » Lost to Yankees (94-59), 9-6 | Griffith Stadium (33-40) | 65-86 | |
| » Starters: Russ VanAtta vs Reese Diggs | Seventh | 33½ out |
| Sunday, September 30 |
| » Defeated Yankees (94-60), 5-3 | Griffith Stadium (34-40) | 66-86 | |
| » Starters: Red Ruffing vs Orville Armbrust | Seventh | 34 out |
| Sunday, October 14 |
| Future Senator Tom Cheney is born in Morgan, GA. |
| Thursday, December 6 |
| Future Senator Dan Dobbek is born in Ontonagon, MI. |
| Tuesday, December 11 |
| Future Senator Lee Maye is born in Tuscaloosa, AL. |
Game information provided by Retrosheet (www.retrosheet.org) |