| Monday, January 2 |
| Former Tiger Kid Gleason dies in Philadelphia, PA at the age of 67. |
| Friday, January 6 |
| Future Tiger Lenny Green is born in Detroit, MI. |
| Tuesday, January 17 |
| Future Tiger J.W. Porter is born in Shawnee, OK. |
| Wednesday, April 12 |
| » Lost to Indians (1-0), 4-1 | Tiger Stadium (0-1) | 0-1 | |
| » Starters: Clint Brown vs Tommy Bridges | Third | 1 out |
| » Major-league debuts: Pete Fox (Tigers) Bill Knickerbocker (Indians) |
| Future Tiger Charlie Lau is born in Romulus, MI. |
| Thursday, April 13 |
| » Lost to Indians (2-0), 7-4 | Tiger Stadium (0-2) | 0-2 | Lost 2 |
| » Starters: Oral Hildebrand vs Firpo Marberry | Fourth | 2 out |
| » Major-league debuts: Frank Reiber (Tigers) |
| Saturday, April 15 |
| » Defeated White Sox (2-1), 3-0 | Tiger Stadium (1-2) | 1-2 | |
| » Starters: Paul Gregory vs Schoolboy Rowe | Fifth | 2 out |
| » Major-league debuts: Schoolboy Rowe (Tigers) |
| Monday, April 17 |
| » Defeated White Sox (2-2), 8-5 | Tiger Stadium (2-2) | 2-2 | Won 2 |
| » Starters: Milt Gaston vs Vic Sorrell | Fourth | 2 out |
| Tuesday, April 18 |
| » Lost to White Sox (3-2), 12-0 | Tiger Stadium (2-3) | 2-3 | |
| » Starters: Sad Sam Jones vs Tommy Bridges | Fourth | 3 out |
| Thursday, April 20 |
| » Lost to Indians (4-2), 3-1 | Cleveland Stadium (0-1) | 2-4 | Lost 2 |
| » Starters: Vic Sorrell vs Clint Brown | Sixth | 3½ out |
| Friday, April 21 |
| » Lost to Indians (5-2), 5-0 | Cleveland Stadium (0-2) | 2-5 | Lost 3 |
| » Starters: Schoolboy Rowe vs Oral Hildebrand | Sixth | 4½ out |
| Saturday, April 22 |
| » Defeated Browns (3-6), 5-1 | Tiger Stadium (3-3) | 3-5 | |
| » Starters: Lloyd Brown vs Firpo Marberry | Fifth | 4½ out |
| Sunday, April 23 |
| » Defeated Browns (3-7), 2-0 | Tiger Stadium (4-3) | 4-5 | Won 2 |
| » Starters: George Blaeholder vs Tommy Bridges | Fifth | 3½ out |
| Monday, April 24 |
| » Defeated Browns (3-8), 4-3 | Tiger Stadium (5-3) | 5-5 | Won 3 |
| » Starters: Dick Coffman vs Carl Fischer | Fourth | 2½ out |
| Tuesday, April 25 |
| » Major-league debuts: Ralph Birkofer and Pep Young (Pirates) |
| Wednesday, April 26 |
| » Defeated White Sox (8-4), 6-4 | Comiskey Park I (1-0) | 6-5 | Won 4 |
| » Starters: Vic Sorrell vs Sad Sam Jones | Fourth | 2½ out |
| Thursday, April 27 |
| » Lost to White Sox (9-4), 10-4 | Comiskey Park I (1-1) | 6-6 | |
| » Starters: Firpo Marberry vs Ed Durham | Fourth | 3½ out |
| Friday, April 28 |
| » Defeated Browns (4-11), 5-3 | Sportsman's Park III (1-0) | 7-6 | |
| » Starters: Tommy Bridges vs Dick Coffman | Fourth | 2½ out |
| Saturday, April 29 |
| » Lost to Browns (5-11), 11-4 | Sportsman's Park III (1-1) | 7-7 | |
| » Starters: Schoolboy Rowe vs Bump Hadley | Third | 2½ out |
| Sunday, April 30 |
| » Lost to Browns (6-11), 11-8 | Sportsman's Park III (1-2) | 7-8 | Lost 2 |
| » Starters: Vic Sorrell vs Lloyd Brown | Fourth | 3½ out |
| » Defeated Browns (6-12), 5-1 | Sportsman's Park III (2-2) | 8-8 | |
| » Starters: Carl Fischer vs Jack Knott | Fourth | 3½ out |
| Tuesday, May 2 |
| » Defeated Yankees (11-5), 3-2 | Tiger Stadium (6-3) | 9-8 | Won 2 |
| » Starters: Red Ruffing vs Firpo Marberry | Fourth | 2½ out |
| Thursday, May 4 |
| » Lost to Yankees (12-5), 5-2 | Tiger Stadium (6-4) | 9-9 | |
| » Starters: Lefty Gomez vs Tommy Bridges | Fourth | 3½ out |
| Saturday, May 6 |
| » Lost to Senators (11-7), 6-2 | Tiger Stadium (6-5) | 9-10 | Lost 2 |
| » Starters: Earl Whitehill vs Carl Fischer | Fourth | 3½ out |
| Sunday, May 7 |
| » Defeated Senators (11-8), 10-9 | Tiger Stadium (7-5) | 10-10 | |
| » Starters: Monte Weaver vs Chief Hogsett | Fourth | 3½ out |
| » Lost to Senators (12-8), 6-2 | Tiger Stadium (7-6) | 10-11 | |
| » Starters: Lefty Stewart vs Schoolboy Rowe | Fourth | 3½ out |
| Wednesday, May 10 |
| » Lost to Athletics (8-11), 3-2 | Tiger Stadium (7-7) | 10-12 | Lost 2 |
| » Starters: Sugar Cain vs Firpo Marberry | Fifth | 4½ out |
| » Lost to Athletics (9-11), 6-4 | Tiger Stadium (7-8) | 10-13 | Lost 3 |
| » Starters: Rube Walberg vs Vic Sorrell | Fifth | 4½ out |
| Sunday, May 14 |
| » Lost to Red Sox (7-15), 6-1 | Tiger Stadium (7-9) | 10-14 | Lost 4 |
| » Starters: Gordon Rhodes vs Tommy Bridges | Fifth | 5½ out |
| » Defeated Red Sox (7-16), 3-2 | Tiger Stadium (8-9) | 11-14 | |
| » Starters: Hank Johnson vs Firpo Marberry | Fifth | 5½ out |
| Tuesday, May 16 |
| Future Tiger Bob Bruce is born in Detroit, MI. |
| Wednesday, May 17 |
| » Lost to Yankees (16-9), 4-1 | Yankee Stadium (0-1) | 11-15 | |
| » Starters: Carl Fischer vs Lefty Gomez | Sixth | 5½ out |
| Future Tiger Ozzie Virgil is born in Monte Cristi, D.R. |
| Thursday, May 18 |
| » Lost to Yankees (17-9), 5-1 | Yankee Stadium (0-2) | 11-16 | Lost 2 |
| » Starters: Vic Sorrell vs Johnny Allen | Fifth | 6½ out |
| Friday, May 19 |
| » Defeated Red Sox (8-19), 7-5 | Fenway Park (1-0) | 12-16 | |
| » Starters: Firpo Marberry vs Gordon Rhodes | Fifth | 6½ out |
| Saturday, May 20 |
| » Lost to Red Sox (9-19), 6-5 | Fenway Park (1-1) | 12-17 | |
| » Starters: Tommy Bridges vs Hank Johnson | Sixth | 6½ out |
| Sunday, May 21 |
| » Lost to Red Sox (10-19), 2-0 | Fenway Park (1-2) | 12-18 | Lost 2 |
| » Starters: Vic Sorrell vs Lloyd Brown | Seventh | 6½ out |
| Monday, May 22 |
| » Lost to Senators (20-14), 6-5 | Griffith Stadium (0-1) | 12-19 | Lost 3 |
| » Starters: Carl Fischer vs Earl Whitehill | Seventh | 7½ out |
| Tuesday, May 23 |
| » Defeated Senators (20-15), 7-1 | Griffith Stadium (1-1) | 13-19 | |
| » Starters: Firpo Marberry vs Lefty Stewart | Sixth | 7½ out |
| Wednesday, May 24 |
| » Defeated Senators (20-16), 3-1 | Griffith Stadium (2-1) | 14-19 | Won 2 |
| » Starters: Tommy Bridges vs Monte Weaver | Sixth | 7 out |
| Thursday, May 25 |
| » Lost to Athletics (18-14), 4-3 | Shibe Park (0-1) | 14-20 | |
| » Starters: Vic Sorrell vs George Earnshaw | Fifth | 7½ out |
| Friday, May 26 |
| » Defeated Athletics (18-15), 10-1 | Shibe Park (1-1) | 15-20 | |
| » Starters: Schoolboy Rowe vs Rube Walberg | Sixth | 6½ out |
| Saturday, May 27 |
| » Lost to Athletics (19-15), 5-2 | Shibe Park (1-2) | 15-21 | |
| » Starters: Firpo Marberry vs Tony Freitas | Fifth | 7½ out |
| Sunday, May 28 |
| » Lost to Browns (15-24), 5-3 | Tiger Stadium (8-10) | 15-22 | Lost 2 |
| » Starters: George Blaeholder vs Chief Hogsett | Sixth | 9 out |
| Tuesday, May 30 |
| » Defeated Browns (15-25), 8-6 | Tiger Stadium (9-10) | 16-22 | |
| » Starters: Bump Hadley vs Carl Fischer | Sixth | 9½ out |
| » Lost to Browns (16-25), 3-1 | Tiger Stadium (9-11) | 16-23 | |
| » Starters: Wally Hebert vs Vic Sorrell | Sixth | 9½ out |
| Thursday, June 1 |
| » Defeated White Sox (20-19), 3-1 | Tiger Stadium (10-11) | 17-23 | |
| » Starters: Ted Lyons vs Schoolboy Rowe | Sixth | 9 out |
| Friday, June 2 |
| » Defeated White Sox (20-20), 14-1 | Tiger Stadium (11-11) | 18-23 | Won 2 |
| » Starters: Milt Gaston vs Art Herring | Fifth | 9 out |
| Future Tiger Jerry Lumpe is born in Lincoln, MO. |
| Saturday, June 3 |
| » Lost to White Sox (21-20), 11-6 | Tiger Stadium (11-12) | 18-24 | |
| » Starters: Sad Sam Jones vs Tommy Bridges | Sixth | 10 out |
| Sunday, June 4 |
| » Lost to Indians (26-20), 2-1 | Cleveland Stadium (0-3) | 18-25 | Lost 2 |
| » Starters: Carl Fischer vs Clint Brown | Sixth | 11 out |
| » Defeated Indians (26-21), 4-3 | Cleveland Stadium (1-3) | 19-25 | |
| » Starters: Firpo Marberry vs Willis Hudlin | Sixth | 11 out |
| Monday, June 5 |
| » Defeated Indians (26-22), 8-7 | Cleveland Stadium (2-3) | 20-25 | Won 2 |
| » Starters: Vic Frasier vs Wes Ferrell | Sixth | 10½ out |
| Tuesday, June 6 |
| » Defeated Indians (26-23), 5-2 | Cleveland Stadium (3-3) | 21-25 | Won 3 |
| » Starters: Schoolboy Rowe vs Mel Harder | Sixth | 11 out |
| Wednesday, June 7 |
| » Defeated Indians (26-24), 3-1 | Cleveland Stadium (4-3) | 22-25 | Won 4 |
| » Starters: Tommy Bridges vs Oral Hildebrand | Sixth | 10½ out |
| Thursday, June 8 |
| » Defeated White Sox (26-21), 3-2 | Comiskey Park I (2-1) | 23-25 | Won 5 |
| » Starters: Art Herring vs Sad Sam Jones | Sixth | 9½ out |
| Friday, June 9 |
| » Lost to White Sox (27-21), 10-9 | Comiskey Park I (2-2) | 23-26 | |
| » Starters: Firpo Marberry vs Ed Durham | Sixth | 10½ out |
| Saturday, June 10 |
| » Defeated White Sox (27-22), 6-4 | Comiskey Park I (3-2) | 24-26 | |
| » Starters: Vic Sorrell vs Paul Gregory | Sixth | 9 out |
| Sunday, June 11 |
| » Lost to White Sox (28-22), 6-1 | Comiskey Park I (3-3) | 24-27 | |
| » Starters: Vic Frasier vs Milt Gaston | Sixth | 9 out |
| » Defeated White Sox (28-23), 5-3 | Comiskey Park I (4-3) | 25-27 | |
| » Starters: Schoolboy Rowe vs Ted Lyons | Sixth | 9 out |
| Tuesday, June 13 |
| » Lost to Indians (29-25), 1-0 | Tiger Stadium (11-13) | 25-28 | |
| » Starters: Oral Hildebrand vs Tommy Bridges | Sixth | 9 out |
| Wednesday, June 14 |
| » Defeated Indians (29-26), 13-2 | Tiger Stadium (12-13) | 26-28 | |
| » Starters: Clint Brown vs Firpo Marberry | Sixth | 8 out |
| Saturday, June 17 |
| » Lost to Indians (30-26), 3-2 | Cleveland Stadium (4-4) | 26-29 | |
| » Starters: Tommy Bridges vs Wes Ferrell | Sixth | 8½ out |
| Sunday, June 18 |
| » Defeated Athletics (27-25), 3-2 | Tiger Stadium (13-13) | 27-29 | |
| » Starters: Rube Walberg vs Vic Sorrell | Sixth | 7½ out |
| » Defeated Athletics (27-26), 11-7 | Tiger Stadium (14-13) | 28-29 | Won 2 |
| » Starters: Roy Mahaffey vs Schoolboy Rowe | Sixth | 7½ out |
| Monday, June 19 |
| » Defeated Athletics (27-27), 9-4 | Tiger Stadium (15-13) | 29-29 | Won 3 |
| » Starters: Lefty Grove vs Vic Frasier | Sixth | 6½ out |
| Tuesday, June 20 |
| » Lost to Athletics (28-27), 9-4 | Tiger Stadium (15-14) | 29-30 | |
| » Starters: Tony Freitas vs Carl Fischer | Sixth | 7½ out |
| Wednesday, June 21 |
| » Lost to Red Sox (23-37), 10-9 | Tiger Stadium (15-15) | 29-31 | Lost 2 |
| » Starters: Gordon Rhodes vs Art Herring | Sixth | 8 out |
| » Defeated Red Sox (23-38), 5-3 | Tiger Stadium (16-15) | 30-31 | |
| » Starters: Ivy Andrews vs Firpo Marberry | Sixth | 8 out |
| Thursday, June 22 |
| » Lost to Red Sox (24-38), 9-7 | Tiger Stadium (16-16) | 30-32 | |
| » Starters: Lloyd Brown vs Vic Sorrell | Fifth | 8 out |
| Friday, June 23 |
| » Lost to Red Sox (25-38), 3-2 | Tiger Stadium (16-17) | 30-33 | Lost 2 |
| » Starters: Bob Weiland vs Schoolboy Rowe | Sixth | 9 out |
| Saturday, June 24 |
| » Defeated Red Sox (25-39), 16-4 | Tiger Stadium (17-17) | 31-33 | |
| » Starters: George Pipgras vs Vic Frasier | Sixth | 9 out |
| Sunday, June 25 |
| » Defeated Yankees (39-25), 6-5 | Tiger Stadium (18-17) | 32-33 | Won 2 |
| » Starters: Johnny Allen vs Tommy Bridges | Sixth | 10 out |
| » Lost to Yankees (40-25), 3-0 | Tiger Stadium (18-18) | 32-34 | |
| » Starters: Russ Van Atta vs Vic Sorrell | Sixth | 10 out |
| Tuesday, June 27 |
| » Lost to Yankees (41-25), 9-8 | Tiger Stadium (18-19) | 32-35 | Lost 2 |
| » Starters: Jumbo Brown vs Firpo Marberry | Sixth | 10½ out |
| Wednesday, June 28 |
| » Lost to Yankees (42-25), 10-7 | Tiger Stadium (18-20) | 32-36 | Lost 3 |
| » Starters: Red Ruffing vs Vic Frasier | Sixth | 11½ out |
| Thursday, June 29 |
| » Defeated Senators (43-25), 5-4 | Tiger Stadium (19-20) | 33-36 | |
| » Starters: Earl Whitehill vs Schoolboy Rowe | Fifth | 10½ out |
| Future Tiger Bob Shaw is born in Bronx, NY. |
| Friday, June 30 |
| » Lost to Senators (44-25), 2-1 | Tiger Stadium (19-21) | 33-37 | |
| » Starters: General Crowder vs Tommy Bridges | Sixth | 11½ out |
| Saturday, July 1 |
| » Lost to Senators (45-25), 11-3 | Tiger Stadium (19-22) | 33-38 | Lost 2 |
| » Starters: Tommy Thomas vs Vic Sorrell | Sixth | 12½ out |
| Monday, July 3 |
| » Defeated Browns (28-48), 8-5 | Sportsman's Park III (3-2) | 34-38 | |
| » Starters: Firpo Marberry vs Dick Coffman | Sixth | 12 out |
| Tuesday, July 4 |
| » Defeated Browns (28-49), 7-4 | Sportsman's Park III (4-2) | 35-38 | Won 2 |
| » Starters: Vic Frasier vs Ed Wells | Sixth | 13 out |
| » Lost to Browns (29-49), 6-5 | Sportsman's Park III (4-3) | 35-39 | |
| » Starters: Schoolboy Rowe vs Wally Hebert | Sixth | 13 out |
| Wednesday, July 5 |
| » Defeated Browns (29-50), 9-4 | Sportsman's Park III (5-3) | 36-39 | |
| » Starters: Tommy Bridges vs George Blaeholder | Sixth | 12½ out |
| Friday, July 7 |
| » Defeated Yankees (45-29), 9-4 | Yankee Stadium (1-2) | 37-39 | Won 2 |
| » Starters: Vic Frasier vs Red Ruffing | Fifth | 12 out |
| Saturday, July 8 |
| » Defeated Yankees (45-30), 5-2 | Yankee Stadium (2-2) | 38-39 | Won 3 |
| » Starters: Firpo Marberry vs Johnny Allen | Fourth | 12½ out |
| Sunday, July 9 |
| » Lost to Yankees (46-30), 11-7 | Yankee Stadium (2-3) | 38-40 | |
| » Starters: Schoolboy Rowe vs Lefty Gomez | Fifth | 14 out |
| » Lost to Yankees (47-30), 7-6 | Yankee Stadium (2-4) | 38-41 | Lost 2 |
| » Starters: Tommy Bridges vs Russ Van Atta | Fifth | 14 out |
| Monday, July 10 |
| » Lost to Yankees (48-30), 10-6 | Yankee Stadium (2-5) | 38-42 | Lost 3 |
| » Starters: Carl Fischer vs Jumbo Brown | Fifth | 14 out |
| Tuesday, July 11 |
| » Lost to Red Sox (33-45), 2-1 | Fenway Park (1-3) | 38-43 | Lost 4 |
| » Starters: Vic Frasier vs Bob Weiland | Fifth | 14 out |
| Wednesday, July 12 |
| » Lost to Red Sox (34-45), 1-0 | Fenway Park (1-4) | 38-44 | Lost 5 |
| » Starters: Vic Sorrell vs Lloyd Brown | Fifth | 15 out |
| Thursday, July 13 |
| » Defeated Red Sox (34-46), 3-2 | Fenway Park (2-4) | 39-44 | |
| » Starters: Firpo Marberry vs Hank Johnson | Fifth | 14 out |
| Friday, July 14 |
| » Defeated Red Sox (34-47), 8-3 | Fenway Park (3-4) | 40-44 | Won 2 |
| » Starters: Tommy Bridges vs George Pipgras | Fifth | 13 out |
| Saturday, July 15 |
| » Lost to Athletics (43-40), 3-2 | Shibe Park (1-3) | 40-45 | |
| » Starters: Schoolboy Rowe vs Lefty Grove | Fifth | 14½ out |
| Tuesday, July 18 |
| » Defeated Athletics (43-41), 5-2 | Shibe Park (2-3) | 41-45 | |
| » Starters: Vic Sorrell vs Rube Walberg | Fifth | 14 out |
| Wednesday, July 19 |
| » Lost to Athletics (44-41), 7-3 | Shibe Park (2-4) | 41-46 | |
| » Starters: Carl Fischer vs Roy Mahaffey | Fourth | 13½ out |
| » Defeated Athletics (44-42), 10-5 | Shibe Park (3-4) | 42-46 | |
| » Starters: Firpo Marberry vs Sugar Cain | Fourth | 13½ out |
| Thursday, July 20 |
| » Defeated Senators (54-32), 1-0 | Griffith Stadium (3-1) | 43-46 | Won 2 |
| » Starters: Tommy Bridges vs General Crowder | Fourth | 12½ out |
| Friday, July 21 |
| » Lost to Senators (55-32), 7-1 | Griffith Stadium (3-2) | 43-47 | |
| » Starters: Vic Frasier vs Earl Whitehill | Fourth | 13½ out |
| Saturday, July 22 |
| » Lost to Senators (56-32), 4-3 | Griffith Stadium (3-3) | 43-48 | Lost 2 |
| » Starters: Firpo Marberry vs Lefty Stewart | Sixth | 14½ out |
| Sunday, July 23 |
| » Defeated Senators (56-33), 12-8 | Griffith Stadium (4-3) | 44-48 | |
| » Starters: Schoolboy Rowe vs Monte Weaver | Fourth | 14 out |
| Tuesday, July 25 |
| » Defeated Browns (35-62), 9-3 | Tiger Stadium (20-22) | 45-48 | Won 2 |
| » Starters: Bump Hadley vs Carl Fischer | Fourth | 14½ out |
| Wednesday, July 26 |
| » Defeated Browns (35-63), 9-7 | Tiger Stadium (21-22) | 46-48 | Won 3 |
| » Starters: Rollie Stiles vs Tommy Bridges | Fourth | 14 out |
| Thursday, July 27 |
| » Lost to Browns (36-63), 10-9 | Tiger Stadium (21-23) | 46-49 | |
| » Starters: Ed Wells vs Firpo Marberry | Fifth | 15 out |
| Friday, July 28 |
| » Lost to Indians (48-50), 7-2 | Cleveland Stadium (4-5) | 46-50 | Lost 2 |
| » Starters: Vic Sorrell vs Oral Hildebrand | Fifth | 15½ out |
| » Major-league debuts: Johnny Pasek (Tigers) |
| Saturday, July 29 |
| » Lost to Indians (49-50), 1-0 | Cleveland Stadium (4-6) | 46-51 | Lost 3 |
| » Starters: Carl Fischer vs Clint Brown | Fifth | 16½ out |
| Sunday, July 30 |
| » Defeated Indians (49-51), 6-1 | Cleveland Stadium (5-6) | 47-51 | |
| » Starters: Tommy Bridges vs Mel Harder | Fifth | 15½ out |
| Wednesday, August 2 |
| » Lost to White Sox (46-52), 2-1 | Tiger Stadium (21-24) | 47-52 | |
| » Starters: Sad Sam Jones vs Firpo Marberry | Sixth | 16½ out |
| » Lost to White Sox (47-52), 4-3 | Tiger Stadium (21-25) | 47-53 | Lost 2 |
| » Starters: Milt Gaston vs Vic Frasier | Sixth | 16½ out |
| Friday, August 4 |
| » Defeated White Sox (47-53), 3-2 | Tiger Stadium (22-25) | 48-53 | |
| » Starters: Ted Lyons vs Vic Sorrell | Fifth | 16½ out |
| Saturday, August 5 |
| » Lost to Indians (52-53), 15-6 | Tiger Stadium (22-26) | 48-54 | |
| » Starters: Clint Brown vs Tommy Bridges | Fifth | 17 out |
| » Defeated Indians (52-54), 7-1 | Tiger Stadium (23-26) | 49-54 | |
| » Starters: Willis Hudlin vs Carl Fischer | Fifth | 17 out |
| Sunday, August 6 |
| » Defeated Indians (52-55), 7-3 | Tiger Stadium (24-26) | 50-54 | Won 2 |
| » Starters: Oral Hildebrand vs Vic Frasier | Fourth | 15½ out |
| » Defeated Indians (52-56), 2-1 | Tiger Stadium (25-26) | 51-54 | Won 3 |
| » Starters: Monte Pearson vs Firpo Marberry | Fourth | 15½ out |
| Monday, August 7 |
| » Defeated Indians (52-57), 6-3 | Tiger Stadium (26-26) | 52-54 | Won 4 |
| » Starters: Mel Harder vs Vic Sorrell | Fourth | 14 out |
| Thursday, August 10 |
| » Lost to White Sox (49-56), 6-3 | Comiskey Park I (4-4) | 52-55 | |
| » Starters: Carl Fischer vs Sad Sam Jones | Fourth | 16 out |
| Future Tiger Rocky Colavito is born in New York, NY. |
| Friday, August 11 |
| » Lost to White Sox (50-56), 2-0 | Comiskey Park I (4-5) | 52-56 | Lost 2 |
| » Starters: Firpo Marberry vs Ted Lyons | Fourth | 17 out |
| Saturday, August 12 |
| » Lost to White Sox (51-56), 11-2 | Comiskey Park I (4-6) | 52-57 | Lost 3 |
| » Starters: Vic Frasier vs Milt Gaston | Sixth | 18 out |
| Sunday, August 13 |
| » Defeated White Sox (51-57), 6-5 | Comiskey Park I (5-6) | 53-57 | |
| » Starters: Vic Sorrell vs Jake Miller | Fifth | 18 out |
| Monday, August 14 |
| » Defeated Red Sox (47-60), 6-5 | Tiger Stadium (27-26) | 54-57 | Won 2 |
| » Starters: George Pipgras vs Elden Auker | Fifth | 17½ out |
| Tuesday, August 15 |
| » Lost to Red Sox (48-60), 5-3 | Tiger Stadium (27-27) | 54-58 | |
| » Starters: Hank Johnson vs Firpo Marberry | Fourth | 18½ out |
| Wednesday, August 16 |
| » Defeated Red Sox (48-61), 6-5 | Tiger Stadium (28-27) | 55-58 | |
| » Starters: Lloyd Brown vs Vic Frasier | Fourth | 18½ out |
| Thursday, August 17 |
| » Lost to Red Sox (49-61), 6-2 | Tiger Stadium (28-28) | 55-59 | |
| » Starters: Bob Weiland vs Elden Auker | Fifth | 19½ out |
| Friday, August 18 |
| » Defeated Athletics (55-56), 7-6 | Tiger Stadium (29-28) | 56-59 | |
| » Starters: Roy Mahaffey vs Vic Sorrell | Fifth | 19½ out |
| Saturday, August 19 |
| » Defeated Athletics (55-57), 6-0 | Tiger Stadium (30-28) | 57-59 | Won 2 |
| » Starters: Rube Walberg vs Firpo Marberry | Fifth | 19½ out |
| Sunday, August 20 |
| » Defeated Athletics (55-58), 5-4 | Tiger Stadium (31-28) | 58-59 | Won 3 |
| » Starters: Lefty Grove vs Vic Frasier | Fourth | 19½ out |
| » Defeated Athletics (55-59), 4-1 | Tiger Stadium (32-28) | 59-59 | Won 4 |
| » Starters: Sugar Cain vs Carl Fischer | Fourth | 19½ out |
| Monday, August 21 |
| » Lost to Athletics (56-59), 12-7 | Tiger Stadium (32-29) | 59-60 | |
| » Starters: Dick Barrett vs Elden Auker | Fourth | 20 out |
| Tuesday, August 22 |
| » Defeated Senators (77-39), 10-8 | Tiger Stadium (33-29) | 60-60 | |
| » Starters: Monte Weaver vs Vic Sorrell | Fourth | 19 out |
| Wednesday, August 23 |
| » Defeated Senators (77-40), 2-1 | Tiger Stadium (34-29) | 61-60 | Won 2 |
| » Starters: General Crowder vs Tommy Bridges | Fourth | 19 out |
| » Lost to Senators (78-40), 9-5 | Tiger Stadium (34-30) | 61-61 | |
| » Starters: Lefty Stewart vs Firpo Marberry | Fourth | 19 out |
| Thursday, August 24 |
| » Lost to Senators (79-40), 13-6 | Tiger Stadium (34-31) | 61-62 | Lost 2 |
| » Starters: Earl Whitehill vs Carl Fischer | Fourth | 20 out |
| Friday, August 25 |
| » Lost to Senators (80-40), 5-4 | Tiger Stadium (34-32) | 61-63 | Lost 3 |
| » Starters: Bobby Burke vs Firpo Marberry | Fifth | 21 out |
| Saturday, August 26 |
| » Lost to Yankees (71-48), 9-5 | Tiger Stadium (34-33) | 61-64 | Lost 4 |
| » Starters: George Uhle vs Vic Sorrell | Fifth | 21 out |
| Sunday, August 27 |
| » Defeated Yankees (71-49), 4-3 | Tiger Stadium (35-33) | 62-64 | |
| » Starters: Lefty Gomez vs Tommy Bridges | Fifth | 21 out |
| » Lost to Yankees (72-49), 12-2 | Tiger Stadium (35-34) | 62-65 | |
| » Starters: Red Ruffing vs Carl Fischer | Fifth | 21 out |
| Monday, August 28 |
| » Defeated Yankees (72-50), 6-1 | Tiger Stadium (36-34) | 63-65 | |
| » Starters: Johnny Allen vs Vic Sorrell | Fifth | 20½ out |
| Tuesday, August 29 |
| » Lost to Yankees (73-50), 11-9 | Tiger Stadium (36-35) | 63-66 | |
| » Starters: Charlie Devens vs Firpo Marberry | Fifth | 21 out |
| Saturday, September 2 |
| » Lost to Browns (48-82), 7-1 | Sportsman's Park III (5-4) | 63-67 | Lost 2 |
| » Starters: Carl Fischer vs Bump Hadley | Fifth | 21 out |
| Sunday, September 3 |
| » Lost to Browns (49-82), 2-1 | Sportsman's Park III (5-5) | 63-68 | Lost 3 |
| » Starters: Tommy Bridges vs George Blaeholder | Fifth | 22 out |
| » Tied Browns, 5-5 | Sportsman's Park III (5-5) | 63-68 | |
| » Starters: Firpo Marberry vs Rollie Stiles | Fifth | 22 out |
| Monday, September 4 |
| » Defeated White Sox (60-71), 8-0 | Tiger Stadium (37-35) | 64-68 | |
| » Starters: Sad Sam Jones vs Vic Sorrell | Fifth | 21 out |
| » Defeated White Sox (60-72), 5-4 | Tiger Stadium (38-35) | 65-68 | Won 2 |
| » Starters: Ted Lyons vs Elden Auker | Fifth | 21 out |
| Tuesday, September 5 |
| » Major-league debuts: Phil Weintraub (Giants) |
| Wednesday, September 6 |
| » Defeated Red Sox (56-78), 11-5 | Fenway Park (4-4) | 66-68 | Won 3 |
| » Starters: Roxie Lawson vs Lloyd Brown | Fifth | 22 out |
| Friday, September 8 |
| » Defeated Red Sox (56-79), 4-3 | Fenway Park (5-4) | 67-68 | Won 4 |
| » Starters: Tommy Bridges vs Ivy Andrews | Fifth | 21 out |
| » Defeated Red Sox (56-80), 4-3 | Fenway Park (6-4) | 68-68 | Won 5 |
| » Starters: Firpo Marberry vs Bob Weiland | Fifth | 21 out |
| » Major-league debuts: Mel Almada (Red Sox) |
| Saturday, September 9 |
| » Lost to Red Sox (57-80), 6-4 | Fenway Park (6-5) | 68-69 | |
| » Starters: Vic Sorrell vs Gordon Rhodes | Fifth | 22 out |
| Sunday, September 10 |
| » Lost to Yankees (79-53), 2-1 | Yankee Stadium (2-6) | 68-70 | Lost 2 |
| » Starters: Carl Fischer vs Lefty Gomez | Fifth | 23½ out |
| » Lost to Yankees (80-53), 9-1 | Yankee Stadium (2-7) | 68-71 | Lost 3 |
| » Starters: Roxie Lawson vs Johnny Allen | Fifth | 23½ out |
| Monday, September 11 |
| » Defeated Yankees (80-54), 5-1 | Yankee Stadium (3-7) | 69-71 | |
| » Starters: Firpo Marberry vs Red Ruffing | Fifth | 23½ out |
| Tuesday, September 12 |
| » Lost to Yankees (81-54), 5-3 | Yankee Stadium (3-8) | 69-72 | |
| » Starters: Tommy Bridges vs George Uhle | Fifth | 23½ out |
| Thursday, September 14 |
| » Lost to Senators (92-47), 4-3 | Griffith Stadium (4-4) | 69-73 | Lost 2 |
| » Starters: Vic Sorrell vs Earl Whitehill | Fifth | 24½ out |
| Saturday, September 16 |
| » Lost to Senators (93-47), 11-4 | Griffith Stadium (4-5) | 69-74 | Lost 3 |
| » Starters: Firpo Marberry vs Lefty Stewart | Fifth | 26½ out |
| » Lost to Senators (94-47), 4-3 | Griffith Stadium (4-6) | 69-75 | Lost 4 |
| » Starters: Carl Fischer vs General Crowder | Fifth | 26½ out |
| Sunday, September 17 |
| » Lost to Senators (95-47), 4-3 | Griffith Stadium (4-7) | 69-76 | Lost 5 |
| » Starters: Tommy Bridges vs Monte Weaver | Fifth | 27½ out |
| Monday, September 18 |
| » Lost to Athletics (73-67), 9-8 | Shibe Park (3-5) | 69-77 | Lost 6 |
| » Starters: Luke Hamlin vs Roy Mahaffey | Fifth | 27½ out |
| » Major-league debuts: Luke Hamlin (Tigers) |
| Tuesday, September 19 |
| » Lost to Athletics (74-67), 5-2 | Shibe Park (3-6) | 69-78 | Lost 7 |
| » Starters: Vic Sorrell vs Sugar Cain | Fifth | 27½ out |
| Wednesday, September 20 |
| » Lost to Athletics (75-67), 2-1 | Shibe Park (3-7) | 69-79 | Lost 8 |
| » Starters: Carl Fischer vs Lefty Grove | Fifth | 28½ out |
| Thursday, September 21 |
| » Defeated Athletics (75-68), 10-3 | Shibe Park (4-7) | 70-79 | |
| » Starters: Elden Auker vs Johnny Marcum | Fifth | 28½ out |
| » Major-league debuts: Frankie Hayes (Athletics) |
| Saturday, September 23 |
| » Defeated Browns (55-92), 5-3 | Tiger Stadium (39-35) | 71-79 | Won 2 |
| » Starters: George Blaeholder vs Luke Hamlin | Fifth | 27½ out |
| Sunday, September 24 |
| » Defeated Browns (55-93), 2-1 | Tiger Stadium (40-35) | 72-79 | Won 3 |
| » Starters: Dick Coffman vs Tommy Bridges | Fifth | 26 out |
| » Defeated Browns (55-94), 5-2 | Tiger Stadium (41-35) | 73-79 | Won 4 |
| » Starters: Jack Knott vs Carl Fischer | Fifth | 26 out |
| Wednesday, September 27 |
| Future Tiger Jerry Casale is born in Brooklyn, NY. |
| Saturday, September 30 |
| » Defeated Indians (75-75), 3-0 | Tiger Stadium (42-35) | 74-79 | Won 5 |
| » Manager: Del Baker |
| » Starters: Thornton Lee vs Elden Auker | Fifth | 26 out |
| Sunday, October 1 |
| » Defeated Indians (75-76), 5-3 | Tiger Stadium (43-35) | 75-79 | Won 6 |
| » Starters: Clint Brown vs Luke Hamlin | Fifth | 25 out |
| Saturday, November 4 |
| Future Tiger Tito Francona is born in Aliquippa, PA. |
| Friday, November 17 |
| Future Tiger Orlando Pena is born in Victoria De Las Tunas, Cuba. |
| Wednesday, December 27 |
| Former Tiger Fritz Buelow dies in Detroit, MI at the age of 58. |
Game information provided by Retrosheet (www.retrosheet.org) |
