| Friday, January 6 |
| Future Senator Lenny Green is born in Detroit, MI. |
| Sunday, January 8 |
| Future Senator Willie Tasby is born in Shreveport, LA. |
| Tuesday, January 17 |
| Future Senator J.W. Porter is born in Shawnee, OK. |
| Tuesday, January 31 |
| Former Senator Beany Jacobson dies in Decatur, IL at the age of 52. |
| Monday, March 6 |
| Future Senator Ted Abernathy is born in Stanley, NC. |
| Saturday, March 11 |
| Future Senator Jack Spring is born in Spokane, WA. |
| Friday, April 7 |
| Future Senator Joe Hicks is born in Ivy, VA. |
| Wednesday, April 12 |
| » Defeated Athletics (0-1), 4-1 | Griffith Stadium (1-0) | 1-0 | |
| » Starters: Tony Freitas vs General Crowder | First | -- |
| Thursday, April 13 |
| » Defeated Athletics (0-2), 11-4 | Griffith Stadium (2-0) | 2-0 | Won 2 |
| » Starters: George Earnshaw vs Earl Whitehill | First | -- |
| Friday, April 14 |
| » Lost to Athletics (1-2), 5-1 | Griffith Stadium (2-1) | 2-1 | |
| » Starters: Lefty Grove vs Lefty Stewart | Second | ½ out |
| Saturday, April 15 |
| » Defeated Red Sox (0-3), 2-1 | Griffith Stadium (3-1) | 3-1 | |
| » Starters: Gordon Rhodes vs Monte Weaver | Third | ½ out |
| Monday, April 17 |
| » Lost to Red Sox (1-3), 4-2 | Griffith Stadium (3-2) | 3-2 | |
| » Starters: Hank Johnson vs General Crowder | Third | 1½ out |
| Tuesday, April 18 |
| » Lost to Red Sox (2-3), 6-4 | Griffith Stadium (3-3) | 3-3 | Lost 2 |
| » Starters: Ivy Andrews vs Earl Whitehill | Third | 2½ out |
| Thursday, April 20 |
| » Lost to Athletics (2-5), 8-1 | Shibe Park (0-1) | 3-4 | Lost 3 |
| » Starters: Lefty Stewart vs Lefty Grove | Fourth | 3 out |
| Friday, April 21 |
| » Lost to Athletics (3-5), 3-1 | Shibe Park (0-2) | 3-5 | Lost 4 |
| » Starters: General Crowder vs Sugar Cain | Fourth | 4 out |
| Saturday, April 22 |
| » Defeated Athletics (3-6), 10-7 | Shibe Park (1-2) | 4-5 | |
| » Starters: Monte Weaver vs Tony Freitas | Fourth | 4 out |
| Future Senator Bob Schmidt is born in St. Louis, MO. |
| Sunday, April 23 |
| » Defeated Yankees (7-1), 5-4 | Griffith Stadium (4-3) | 5-5 | Won 2 |
| » Starters: Lefty Gomez vs Earl Whitehill | Fourth | 3 out |
| Monday, April 24 |
| » Defeated Yankees (7-2), 11-10 | Griffith Stadium (5-3) | 6-5 | Won 3 |
| » Starters: Don Brennan vs Lefty Stewart | Third | 2 out |
| Tuesday, April 25 |
| » Lost to Yankees (8-2), 16-0 | Griffith Stadium (5-4) | 6-6 | |
| » Starters: Russ Van Atta vs Monte Weaver | Fifth | 3 out |
| » Major-league debuts: Russ Van Atta (Yankees) |
| Thursday, April 27 |
| » Defeated Red Sox (4-7), 3-2 | Fenway Park (1-0) | 7-6 | |
| » Starters: Ed Linke vs Gordon Rhodes | Third | 3 out |
| » Major-league debuts: Ed Linke (Senators) |
| Friday, April 28 |
| » Defeated Yankees (9-3), 4-3 | Yankee Stadium (1-0) | 8-6 | Won 2 |
| » Starters: Lefty Stewart vs George Pipgras | Third | 2 out |
| Saturday, April 29 |
| » Defeated Yankees (9-4), 6-3 | Yankee Stadium (2-0) | 9-6 | Won 3 |
| » Starters: Monte Weaver vs Lefty Gomez | Second | 1 out |
| Sunday, April 30 |
| » Defeated Athletics (6-10), 5-4 | Griffith Stadium (6-4) | 10-6 | Won 4 |
| » Starters: Rube Walberg vs General Crowder | Second | 1½ out |
| Thursday, May 4 |
| » Lost to Indians (11-7), 6-5 | Cleveland Stadium (0-1) | 10-7 | |
| » Starters: General Crowder vs Mel Harder | Third | 2 out |
| Friday, May 5 |
| Future Senator Joe McClain is born in Johnson City, TN. |
| Saturday, May 6 |
| » Defeated Tigers (9-10), 6-2 | Tiger Stadium (1-0) | 11-7 | |
| » Starters: Earl Whitehill vs Carl Fischer | Third | 1 out |
| Sunday, May 7 |
| » Lost to Tigers (10-10), 10-9 | Tiger Stadium (1-1) | 11-8 | |
| » Starters: Monte Weaver vs Chief Hogsett | Third | 1 out |
| » Defeated Tigers (10-11), 6-2 | Tiger Stadium (2-1) | 12-8 | |
| » Starters: Lefty Stewart vs Schoolboy Rowe | Third | 1 out |
| Monday, May 8 |
| » Defeated Browns (7-15), 10-8 | Sportsman's Park III (1-0) | 13-8 | Won 2 |
| » Starters: Tommy Thomas vs Lloyd Brown | Second | 1 out |
| Tuesday, May 9 |
| » Defeated Browns (7-16), 7-5 | Sportsman's Park III (2-0) | 14-8 | Won 3 |
| » Starters: Ed Linke vs Ed Wells | Second | ½ out |
| Wednesday, May 10 |
| » Lost to Browns (8-16), 5-0 | Sportsman's Park III (2-1) | 14-9 | |
| » Starters: Earl Whitehill vs George Blaeholder | Second | ½ out |
| Thursday, May 11 |
| » Lost to Browns (9-16), 4-3 | Sportsman's Park III (2-2) | 14-10 | Lost 2 |
| » Starters: Lefty Stewart vs Bump Hadley | Fourth | 1½ out |
| Saturday, May 13 |
| » Defeated White Sox (13-10), 5-4 | Comiskey Park I (1-0) | 15-10 | |
| » Starters: General Crowder vs Paul Gregory | Third | 1½ out |
| Future Senator Johnny Roseboro is born in Ashland, OH. |
| Sunday, May 14 |
| » Lost to White Sox (14-10), 10-8 | Comiskey Park I (1-1) | 15-11 | |
| » Starters: Earl Whitehill vs Ted Lyons | Third | 1½ out |
| » Defeated White Sox (14-11), 11-9 | Comiskey Park I (2-1) | 16-11 | |
| » Starters: Tommy Thomas vs Sad Sam Jones | Third | 1½ out |
| Tuesday, May 16 |
| » Defeated Indians (17-11), 11-10 | Griffith Stadium (7-4) | 17-11 | Won 2 |
| » Starters: Belve Bean vs Lefty Stewart | Second | 2 out |
| » Major-league debuts: Cecil Travis (Senators) |
| Wednesday, May 17 |
| » Defeated Indians (17-12), 3-2 | Griffith Stadium (8-4) | 18-11 | Won 3 |
| » Starters: Wes Ferrell vs General Crowder | Second | 2 out |
| Thursday, May 18 |
| » Lost to Indians (18-12), 6-5 | Griffith Stadium (8-5) | 18-12 | |
| » Starters: Oral Hildebrand vs Earl Whitehill | Second | 2 out |
| Friday, May 19 |
| » Lost to White Sox (16-12), 10-1 | Griffith Stadium (8-6) | 18-13 | Lost 2 |
| » Starters: Paul Gregory vs Tommy Thomas | Second | 2 out |
| Saturday, May 20 |
| » Defeated White Sox (16-13), 7-0 | Griffith Stadium (9-6) | 19-13 | |
| » Starters: Ted Lyons vs Monte Weaver | Second | 2 out |
| Sunday, May 21 |
| » Lost to White Sox (17-13), 6-0 | Griffith Stadium (9-7) | 19-14 | |
| » Starters: Jake Miller vs General Crowder | Second | 2 out |
| Monday, May 22 |
| » Defeated Tigers (12-19), 6-5 | Griffith Stadium (10-7) | 20-14 | |
| » Starters: Carl Fischer vs Earl Whitehill | Second | 2 out |
| Tuesday, May 23 |
| » Lost to Tigers (13-19), 7-1 | Griffith Stadium (10-8) | 20-15 | |
| » Starters: Firpo Marberry vs Lefty Stewart | Second | 2 out |
| Wednesday, May 24 |
| » Lost to Tigers (14-19), 3-1 | Griffith Stadium (10-9) | 20-16 | Lost 2 |
| » Starters: Tommy Bridges vs Monte Weaver | Third | 2½ out |
| Thursday, May 25 |
| » Defeated Browns (14-23), 7-2 | Griffith Stadium (11-9) | 21-16 | |
| » Starters: Wally Hebert vs General Crowder | Second | 3 out |
| Friday, May 26 |
| » Defeated Browns (14-24), 5-2 | Griffith Stadium (12-9) | 22-16 | Won 2 |
| » Starters: George Blaeholder vs Earl Whitehill | Second | 3 out |
| Sunday, May 28 |
| » Defeated Athletics (19-16), 7-4 | Griffith Stadium (13-9) | 23-16 | Won 3 |
| » Starters: Rube Walberg vs Lefty Stewart | Second | 2 out |
| Tuesday, May 30 |
| » Lost to Yankees (24-12), 3-2 | Griffith Stadium (13-10) | 23-17 | |
| » Starters: Russ Van Atta vs Earl Whitehill | Second | 3 out |
| Wednesday, May 31 |
| » Defeated Yankees (24-13), 12-7 | Griffith Stadium (14-10) | 24-17 | |
| » Starters: Red Ruffing vs General Crowder | Second | 3 out |
| » Lost to Yankees (25-13), 9-7 | Griffith Stadium (14-11) | 24-18 | |
| » Starters: Herb Pennock vs Monte Weaver | Second | 3 out |
| Thursday, June 1 |
| » Lost to Red Sox (14-25), 7-5 | Griffith Stadium (14-12) | 24-19 | Lost 2 |
| » Starters: Hank Johnson vs Bill McAfee | Third | 3½ out |
| Friday, June 2 |
| » Defeated Red Sox (14-26), 8-3 | Griffith Stadium (15-12) | 25-19 | |
| » Starters: Bob Weiland vs Monte Weaver | Second | 3½ out |
| Saturday, June 3 |
| » Defeated Red Sox (14-27), 8-5 | Griffith Stadium (16-12) | 26-19 | Won 2 |
| » Starters: Lloyd Brown vs Earl Whitehill | Second | 3½ out |
| Sunday, June 4 |
| » Defeated Red Sox (14-28), 4-3 | Griffith Stadium (17-12) | 27-19 | Won 3 |
| » Starters: George Pipgras vs Tommy Thomas | Second | 4 out |
| Monday, June 5 |
| » Lost to Athletics (22-20), 7-4 | Shibe Park (1-3) | 27-20 | |
| » Starters: General Crowder vs Lefty Grove | Second | 4½ out |
| Tuesday, June 6 |
| » Lost to Athletics (23-20), 8-4 | Shibe Park (1-4) | 27-21 | Lost 2 |
| » Starters: Lefty Stewart vs Roy Mahaffey | Second | 6 out |
| Wednesday, June 7 |
| » Tied Athletics, 13-13 | Shibe Park (1-4) | 27-21 | |
| » Starters: Earl Whitehill vs Gowell Claset | Third | 6 out |
| Thursday, June 8 |
| » Lost to Red Sox (15-30), 4-3 | Fenway Park (1-1) | 27-22 | Lost 3 |
| » Starters: Tommy Thomas vs Lloyd Brown | Second | 5½ out |
| » Defeated Red Sox (15-31), 12-3 | Fenway Park (2-1) | 28-22 | |
| » Starters: Jack Russell vs Johnny Welch | Second | 5½ out |
| Friday, June 9 |
| » Defeated Red Sox (15-32), 7-2 | Fenway Park (3-1) | 29-22 | Won 2 |
| » Starters: Earl Whitehill vs George Pipgras | Second | 5½ out |
| Saturday, June 10 |
| » Defeated Red Sox (15-33), 7-5 | Fenway Park (4-1) | 30-22 | Won 3 |
| » Starters: Lefty Stewart vs Hank Johnson | Second | 4 out |
| Former Senator Jack O'Brien dies in Watervliet, NY at the age of 61. |
| Sunday, June 11 |
| » Defeated Athletics (26-22), 13-6 | Griffith Stadium (18-12) | 31-22 | Won 4 |
| » Starters: Roy Mahaffey vs General Crowder | Second | 3½ out |
| Tuesday, June 13 |
| » Defeated Athletics (26-23), 10-6 | Griffith Stadium (19-12) | 32-22 | Won 5 |
| » Starters: Rube Walberg vs Tommy Thomas | Second | 2½ out |
| Saturday, June 17 |
| » Defeated Browns (20-37), 10-3 | Sportsman's Park III (3-2) | 33-22 | Won 6 |
| » Starters: Earl Whitehill vs Ed Wells | Second | 1½ out |
| Sunday, June 18 |
| » Defeated Browns (20-38), 14-1 | Sportsman's Park III (4-2) | 34-22 | Won 7 |
| » Starters: General Crowder vs George Blaeholder | Second | 1½ out |
| » Lost to Browns (21-38), 3-2 | Sportsman's Park III (4-3) | 34-23 | |
| » Starters: Tommy Thomas vs Bump Hadley | Second | 1½ out |
| Monday, June 19 |
| » Defeated Browns (21-39), 10-4 | Sportsman's Park III (5-3) | 35-23 | |
| » Starters: Lefty Stewart vs Wally Hebert | Second | ½ out |
| Wednesday, June 21 |
| » Defeated White Sox (31-29), 9-0 | Comiskey Park I (3-1) | 36-23 | Won 2 |
| » Starters: Earl Whitehill vs Paul Gregory | Second | 1 out |
| Thursday, June 22 |
| » Defeated White Sox (31-30), 11-4 | Comiskey Park I (4-1) | 37-23 | Won 3 |
| » Starters: General Crowder vs Jake Miller | First | -- |
| Friday, June 23 |
| » Defeated White Sox (31-31), 7-3 | Comiskey Park I (5-1) | 38-23 | Won 4 |
| » Starters: Tommy Thomas vs Ted Lyons | First | -- |
| Saturday, June 24 |
| » Defeated White Sox (31-32), 7-5 | Comiskey Park I (6-1) | 39-23 | Won 5 |
| » Starters: Lefty Stewart vs Milt Gaston | First | -- |
| Sunday, June 25 |
| » Defeated Indians (33-32), 9-0 | Cleveland Stadium (1-1) | 40-23 | Won 6 |
| » Starters: Earl Whitehill vs Wes Ferrell | First | -- |
| » Defeated Indians (33-33), 10-1 | Cleveland Stadium (2-1) | 41-23 | Won 7 |
| » Starters: Bobby Burke vs Belve Bean | First | -- |
| » Major-league debuts: Milt Galatzer (Indians) |
| Monday, June 26 |
| » Defeated Indians (33-34), 4-3 | Cleveland Stadium (3-1) | 42-23 | Won 8 |
| » Starters: General Crowder vs Oral Hildebrand | First | -- |
| Future Senator Gene Green is born in Los Angeles, CA. |
| Tuesday, June 27 |
| » Lost to Indians (34-34), 7-6 | Cleveland Stadium (3-2) | 42-24 | |
| » Starters: Tommy Thomas vs Mel Harder | First | -- |
| Wednesday, June 28 |
| » Defeated Indians (34-35), 15-2 | Cleveland Stadium (4-2) | 43-24 | |
| » Starters: Lefty Stewart vs Wes Ferrell | First | -- |
| Thursday, June 29 |
| » Lost to Tigers (33-36), 5-4 | Tiger Stadium (2-2) | 43-25 | |
| » Starters: Earl Whitehill vs Schoolboy Rowe | First | -- |
| Friday, June 30 |
| » Defeated Tigers (33-37), 2-1 | Tiger Stadium (3-2) | 44-25 | |
| » Starters: General Crowder vs Tommy Bridges | First | -- |
| Saturday, July 1 |
| » Defeated Tigers (33-38), 11-3 | Tiger Stadium (4-2) | 45-25 | Won 2 |
| » Starters: Tommy Thomas vs Vic Sorrell | First | -- |
| Tuesday, July 4 |
| » Defeated Yankees (45-27), 6-5 | Yankee Stadium (3-0) | 46-25 | Won 3 |
| » Starters: Earl Whitehill vs Lefty Gomez | First | -- |
| » Defeated Yankees (45-28), 3-2 | Yankee Stadium (4-0) | 47-25 | Won 4 |
| » Starters: Lefty Stewart vs Russ Van Atta | First | -- |
| Saturday, July 8 |
| » Defeated Indians (37-41), 6-2 | Griffith Stadium (20-12) | 48-25 | Won 5 |
| » Starters: Wes Ferrell vs General Crowder | First | -- |
| » Defeated Indians (37-42), 5-4 | Griffith Stadium (21-12) | 49-25 | Won 6 |
| » Starters: Oral Hildebrand vs Earl Whitehill | First | -- |
| Sunday, July 9 |
| » Defeated Indians (37-43), 3-2 | Griffith Stadium (22-12) | 50-25 | Won 7 |
| » Starters: Monte Pearson vs Tommy Thomas | First | -- |
| Monday, July 10 |
| » Lost to Indians (38-43), 3-2 | Griffith Stadium (22-13) | 50-26 | |
| » Starters: Mel Harder vs Lefty Stewart | First | -- |
| Tuesday, July 11 |
| » Lost to White Sox (40-40), 9-3 | Griffith Stadium (22-14) | 50-27 | Lost 2 |
| » Starters: Jake Miller vs General Crowder | First | -- |
| Wednesday, July 12 |
| » Defeated White Sox (40-41), 4-1 | Griffith Stadium (23-14) | 51-27 | |
| » Starters: Ed Durham vs Earl Whitehill | First | -- |
| Thursday, July 13 |
| » Lost to White Sox (41-41), 9-6 | Griffith Stadium (23-15) | 51-28 | |
| » Starters: Paul Gregory vs Tommy Thomas | First | -- |
| Friday, July 14 |
| » Lost to White Sox (42-41), 4-0 | Griffith Stadium (23-16) | 51-29 | Lost 2 |
| » Starters: Jake Miller vs General Crowder | First | -- |
| Saturday, July 15 |
| » Defeated Browns (32-56), 1-0 | Griffith Stadium (24-16) | 52-29 | |
| » Starters: Ed Wells vs Lefty Stewart | First | -- |
| » Defeated Browns (32-57), 2-0 | Griffith Stadium (25-16) | 53-29 | Won 2 |
| » Starters: Rollie Stiles vs Bobby Burke | First | -- |
| Sunday, July 16 |
| » Lost to Browns (33-57), 7-0 | Griffith Stadium (25-17) | 53-30 | |
| » Starters: Bump Hadley vs Earl Whitehill | First | -- |
| Tuesday, July 18 |
| » Lost to Browns (34-57), 4-3 | Griffith Stadium (25-18) | 53-31 | Lost 2 |
| » Starters: George Blaeholder vs Jack Russell | Second | 1 out |
| Wednesday, July 19 |
| » Defeated Browns (34-58), 8-7 | Griffith Stadium (26-18) | 54-31 | |
| » Starters: Ed Wells vs Lefty Stewart | First | -- |
| Thursday, July 20 |
| » Lost to Tigers (43-46), 1-0 | Griffith Stadium (26-19) | 54-32 | |
| » Starters: Tommy Bridges vs General Crowder | First | -- |
| Friday, July 21 |
| » Defeated Tigers (43-47), 7-1 | Griffith Stadium (27-19) | 55-32 | |
| » Starters: Vic Frasier vs Earl Whitehill | First | -- |
| Saturday, July 22 |
| » Defeated Tigers (43-48), 4-3 | Griffith Stadium (28-19) | 56-32 | Won 2 |
| » Starters: Firpo Marberry vs Lefty Stewart | First | -- |
| Sunday, July 23 |
| » Lost to Tigers (44-48), 12-8 | Griffith Stadium (28-20) | 56-33 | |
| » Starters: Schoolboy Rowe vs Monte Weaver | Second | ½ out |
| Former Senator Rip Williams dies in Keokuk, IA at the age of 52. |
| Monday, July 24 |
| » Defeated Athletics (47-44), 5-2 | Shibe Park (2-4) | 57-33 | |
| » Starters: Bobby Burke vs Lefty Grove | First | -- |
| » Defeated Athletics (47-45), 10-6 | Shibe Park (3-4) | 58-33 | Won 2 |
| » Starters: General Crowder vs George Earnshaw | First | -- |
| Tuesday, July 25 |
| » Defeated Athletics (47-46), 5-1 | Shibe Park (4-4) | 59-33 | Won 3 |
| » Starters: Earl Whitehill vs Roy Mahaffey | First | -- |
| Thursday, July 27 |
| » Defeated Yankees (58-35), 3-2 | Griffith Stadium (29-20) | 60-33 | Won 4 |
| » Starters: Red Ruffing vs Lefty Stewart | First | -- |
| Friday, July 28 |
| » Major-league debuts: Johnny Pasek (Tigers) |
| Saturday, July 29 |
| » Defeated Yankees (58-36), 11-5 | Griffith Stadium (30-20) | 61-33 | Won 5 |
| » Starters: Johnny Allen vs General Crowder | First | -- |
| Sunday, July 30 |
| » Lost to Yankees (59-36), 7-2 | Griffith Stadium (30-21) | 61-34 | |
| » Starters: Russ Van Atta vs Earl Whitehill | First | -- |
| Monday, July 31 |
| » Lost to Yankees (60-36), 13-9 | Griffith Stadium (30-22) | 61-35 | Lost 2 |
| » Starters: Lefty Gomez vs Lefty Stewart | First | -- |
| Wednesday, August 2 |
| » Defeated Red Sox (44-52), 2-1 | Griffith Stadium (31-22) | 62-35 | |
| » Starters: Bob Weiland vs General Crowder | First | -- |
| Thursday, August 3 |
| » Defeated Red Sox (44-53), 8-4 | Griffith Stadium (32-22) | 63-35 | Won 2 |
| » Starters: Johnny Welch vs Earl Whitehill | First | -- |
| Saturday, August 5 |
| » Defeated Red Sox (44-54), 3-2 | Griffith Stadium (33-22) | 64-35 | Won 3 |
| » Starters: Gordon Rhodes vs Monte Weaver | First | -- |
| Sunday, August 6 |
| » Lost to Athletics (51-49), 12-8 | Griffith Stadium (33-23) | 64-36 | |
| » Starters: Sugar Cain vs Ed Chapman | First | -- |
| Monday, August 7 |
| » Lost to Yankees (62-39), 6-5 | Yankee Stadium (4-1) | 64-37 | Lost 2 |
| » Starters: General Crowder vs Russ Van Atta | First | -- |
| » Lost to Yankees (63-39), 5-4 | Yankee Stadium (4-2) | 64-38 | Lost 3 |
| » Starters: Lefty Stewart vs Red Ruffing | First | -- |
| Tuesday, August 8 |
| » Defeated Yankees (63-40), 5-1 | Yankee Stadium (5-2) | 65-38 | |
| » Starters: Earl Whitehill vs Johnny Allen | First | -- |
| Wednesday, August 9 |
| » Defeated Yankees (63-41), 4-1 | Yankee Stadium (6-2) | 66-38 | Won 2 |
| » Starters: Monte Weaver vs Lefty Gomez | First | -- |
| Thursday, August 10 |
| » Defeated Red Sox (46-57), 5-3 | Fenway Park (5-1) | 67-38 | Won 3 |
| » Starters: General Crowder vs Gordon Rhodes | First | -- |
| Friday, August 11 |
| » Defeated Red Sox (46-58), 8-4 | Fenway Park (6-1) | 68-38 | Won 4 |
| » Starters: Tommy Thomas vs Hank Johnson | First | -- |
| Saturday, August 12 |
| » Defeated Red Sox (46-59), 2-1 | Fenway Park (7-1) | 69-38 | Won 5 |
| » Starters: Earl Whitehill vs Bob Weiland | First | -- |
| Sunday, August 13 |
| » Defeated Yankees (64-43), 4-3 | Griffith Stadium (34-23) | 70-38 | Won 6 |
| » Starters: Russ Van Atta vs Lefty Stewart | First | -- |
| Tuesday, August 15 |
| » Defeated White Sox (51-58), 5-1 | Comiskey Park I (7-1) | 71-38 | Won 7 |
| » Starters: General Crowder vs Sad Sam Jones | First | -- |
| Wednesday, August 16 |
| » Defeated White Sox (51-59), 5-1 | Comiskey Park I (8-1) | 72-38 | Won 8 |
| » Starters: Earl Whitehill vs Milt Gaston | First | -- |
| Thursday, August 17 |
| » Defeated White Sox (51-60), 14-1 | Comiskey Park I (9-1) | 73-38 | Won 9 |
| » Starters: Monte Weaver vs Jake Miller | First | -- |
| Friday, August 18 |
| » Defeated White Sox (51-61), 6-4 | Comiskey Park I (10-1) | 74-38 | Won 10 |
| » Starters: Tommy Thomas vs Jake Miller | First | -- |
| Saturday, August 19 |
| » Defeated Browns (44-74), 5-3 | Sportsman's Park III (6-3) | 75-38 | Won 11 |
| » Starters: General Crowder vs Bump Hadley | First | -- |
| Sunday, August 20 |
| » Defeated Browns (44-75), 2-1 | Sportsman's Park III (7-3) | 76-38 | Won 12 |
| » Starters: Earl Whitehill vs George Blaeholder | First | -- |
| » Defeated Browns (44-76), 4-3 | Sportsman's Park III (8-3) | 77-38 | Won 13 |
| » Starters: Lefty Stewart vs Ed Wells | First | -- |
| Tuesday, August 22 |
| » Lost to Tigers (60-60), 10-8 | Tiger Stadium (4-3) | 77-39 | |
| » Starters: Monte Weaver vs Vic Sorrell | First | -- |
| Wednesday, August 23 |
| » Lost to Tigers (61-60), 2-1 | Tiger Stadium (4-4) | 77-40 | Lost 2 |
| » Starters: General Crowder vs Tommy Bridges | First | -- |
| » Defeated Tigers (61-61), 9-5 | Tiger Stadium (5-4) | 78-40 | |
| » Starters: Lefty Stewart vs Firpo Marberry | First | -- |
| Thursday, August 24 |
| » Defeated Tigers (61-62), 13-6 | Tiger Stadium (6-4) | 79-40 | Won 2 |
| » Starters: Earl Whitehill vs Carl Fischer | First | -- |
| Friday, August 25 |
| » Defeated Tigers (61-63), 5-4 | Tiger Stadium (7-4) | 80-40 | Won 3 |
| » Starters: Bobby Burke vs Firpo Marberry | First | -- |
| Saturday, August 26 |
| » Lost to Indians (65-61), 5-4 | Cleveland Stadium (4-3) | 80-41 | |
| » Starters: Monte Weaver vs Wes Ferrell | First | -- |
| Sunday, August 27 |
| » Defeated Indians (65-62), 14-1 | Cleveland Stadium (5-3) | 81-41 | |
| » Starters: Earl Whitehill vs Mel Harder | First | -- |
| » Lost to Indians (66-62), 6-3 | Cleveland Stadium (5-4) | 81-42 | |
| » Starters: General Crowder vs Clint Brown | First | -- |
| Tuesday, August 29 |
| » Defeated Indians (66-63), 2-1 | Cleveland Stadium (6-4) | 82-42 | |
| » Starters: Lefty Stewart vs Oral Hildebrand | First | -- |
| » Lost to Indians (67-63), 7-2 | Cleveland Stadium (6-5) | 82-43 | |
| » Starters: Bobby Burke vs Monte Pearson | First | -- |
| Friday, September 1 |
| » Lost to Athletics (62-63), 12-3 | Shibe Park (4-5) | 82-44 | Lost 2 |
| » Starters: Earl Whitehill vs Sugar Cain | First | -- |
| Saturday, September 2 |
| » Lost to Athletics (63-63), 7-3 | Shibe Park (4-6) | 82-45 | Lost 3 |
| » Starters: Jack Russell vs Lefty Grove | First | -- |
| » Defeated Athletics (63-64), 8-4 | Shibe Park (5-6) | 83-45 | |
| » Starters: General Crowder vs Jim Peterson | First | -- |
| Sunday, September 3 |
| » Defeated Red Sox (56-75), 3-2 | Griffith Stadium (35-23) | 84-45 | Won 2 |
| » Starters: Ivy Andrews vs Monte Weaver | First | -- |
| Tuesday, September 5 |
| » Defeated Red Sox (56-76), 5-4 | Fenway Park (8-1) | 85-45 | Won 3 |
| » Starters: Lefty Stewart vs Gordon Rhodes | First | -- |
| » Defeated Red Sox (56-77), 9-6 | Fenway Park (9-1) | 86-45 | Won 4 |
| » Starters: Earl Whitehill vs Johnny Welch | First | -- |
| Wednesday, September 6 |
| » Defeated White Sox (60-73), 3-1 | Griffith Stadium (36-23) | 87-45 | Won 5 |
| » Starters: Jake Miller vs Alex McColl | First | -- |
| Thursday, September 7 |
| » Lost to White Sox (61-73), 1-0 | Griffith Stadium (36-24) | 87-46 | |
| » Starters: Sad Sam Jones vs Monte Weaver | First | -- |
| Friday, September 8 |
| » Defeated White Sox (61-74), 11-2 | Griffith Stadium (37-24) | 88-46 | |
| » Starters: Joe Heving vs General Crowder | First | -- |
| Saturday, September 9 |
| » Defeated White Sox (61-75), 3-2 | Griffith Stadium (38-24) | 89-46 | Won 2 |
| » Starters: Ed Durham vs Earl Whitehill | First | -- |
| Sunday, September 10 |
| » Defeated Indians (72-68), 7-3 | Griffith Stadium (39-24) | 90-46 | Won 3 |
| » Starters: Oral Hildebrand vs Lefty Stewart | First | -- |
| Monday, September 11 |
| » Defeated Indians (72-69), 5-1 | Griffith Stadium (40-24) | 91-46 | Won 4 |
| » Starters: Mel Harder vs Monte Weaver | First | -- |
| » Major-league debuts: Hal Trosky (Indians) |
| Tuesday, September 12 |
| » Lost to Indians (73-69), 3-1 | Griffith Stadium (40-25) | 91-47 | |
| » Starters: Monte Pearson vs General Crowder | First | -- |
| Future Senator Dave Stenhouse is born in Westerly, RI. |
| Thursday, September 14 |
| » Defeated Tigers (69-73), 4-3 | Griffith Stadium (41-25) | 92-47 | |
| » Starters: Vic Sorrell vs Earl Whitehill | First | -- |
| Saturday, September 16 |
| » Defeated Tigers (69-74), 11-4 | Griffith Stadium (42-25) | 93-47 | Won 2 |
| » Starters: Firpo Marberry vs Lefty Stewart | First | -- |
| » Defeated Tigers (69-75), 4-3 | Griffith Stadium (43-25) | 94-47 | Won 3 |
| » Starters: Carl Fischer vs General Crowder | First | -- |
| Sunday, September 17 |
| » Defeated Tigers (69-76), 4-3 | Griffith Stadium (44-25) | 95-47 | Won 4 |
| » Starters: Tommy Bridges vs Monte Weaver | First | -- |
| Monday, September 18 |
| » Lost to Browns (54-89), 4-2 | Griffith Stadium (44-26) | 95-48 | |
| » Starters: Sam Gray vs Bobby Burke | First | -- |
| Tuesday, September 19 |
| » Lost to Browns (55-89), 4-0 | Griffith Stadium (44-27) | 95-49 | Lost 2 |
| » Starters: Dick Coffman vs Earl Whitehill | First | -- |
| Wednesday, September 20 |
| » Defeated Browns (55-90), 13-5 | Griffith Stadium (45-27) | 96-49 | |
| » Starters: Ed Wells vs General Crowder | First | -- |
| Thursday, September 21 |
| » Defeated Browns (55-91), 2-1 | Griffith Stadium (46-27) | 97-49 | Won 2 |
| » Starters: Bump Hadley vs Lefty Stewart | First | -- |
| Saturday, September 23 |
| » Lost to Athletics (76-68), 3-1 | Griffith Stadium (46-28) | 97-50 | |
| » Starters: Sugar Cain vs Monte Weaver | First | -- |
| Sunday, September 24 |
| » Lost to Athletics (77-68), 11-4 | Griffith Stadium (46-29) | 97-51 | Lost 2 |
| » Starters: Tim McKeithan vs General Crowder | First | -- |
| » Major-league debuts: Ray Prim (Senators) |
| Thursday, September 28 |
| » Lost to Yankees (90-57), 11-9 | Yankee Stadium (6-3) | 97-52 | Lost 3 |
| » Starters: Lefty Stewart vs Russ Van Atta | First | -- |
| Friday, September 29 |
| » Defeated Yankees (90-58), 8-5 | Yankee Stadium (7-3) | 98-52 | |
| » Starters: Earl Whitehill vs Red Ruffing | First | -- |
| Saturday, September 30 |
| » Defeated Yankees (90-59), 7-2 | Yankee Stadium (8-3) | 99-52 | Won 2 |
| » Starters: Monte Weaver vs George Uhle | First | -- |
| Sunday, October 1 |
| » Lost to Athletics (79-72), 3-0 | Griffith Stadium (46-30) | 99-53 | |
| » Starters: Rube Walberg vs Ray Prim | First | -- |
Game information provided by Retrosheet (www.retrosheet.org) |