| Friday, January 6 |
| Future Red Sox Lenny Green is born in Detroit, MI. |
| Sunday, January 8 |
| Future Red Sox Willie Tasby is born in Shreveport, LA. |
| Friday, January 20 |
| Future Red Sox Gene Stephens is born in Gravette, AR. |
| Tuesday, January 31 |
| Former Red Sox Beany Jacobson dies in Decatur, IL at the age of 52. |
| Tuesday, February 14 |
| Future Red Sox Tom Borland is born in ElDorado, KS. |
| Saturday, March 11 |
| Future Red Sox Jack Spring is born in Spokane, WA. |
| Thursday, April 13 |
| » Lost to Yankees (1-0), 4-3 | Yankee Stadium (0-1) | 0-1 | |
| » Starters: Ivy Andrews vs Lefty Gomez | Third | 1½ out |
| Friday, April 14 |
| » Lost to Yankees (2-0), 6-2 | Yankee Stadium (0-2) | 0-2 | Lost 2 |
| » Starters: Bob Weiland vs Red Ruffing | Fourth | 2 out |
| Saturday, April 15 |
| » Lost to Senators (3-1), 2-1 | Griffith Stadium (0-1) | 0-3 | Lost 3 |
| » Starters: Gordon Rhodes vs Monte Weaver | Eighth | 3 out |
| Sunday, April 16 |
| » Major-league debuts: Don Brennan (Yankees) |
| Monday, April 17 |
| » Defeated Senators (3-2), 4-2 | Griffith Stadium (1-1) | 1-3 | |
| » Starters: Hank Johnson vs General Crowder | Fifth | 3 out |
| Tuesday, April 18 |
| » Defeated Senators (3-3), 6-4 | Griffith Stadium (2-1) | 2-3 | Won 2 |
| » Starters: Ivy Andrews vs Earl Whitehill | Fourth | 3 out |
| Thursday, April 20 |
| » Major-league debuts: Jimmy Jordan (Dodgers) |
| Friday, April 21 |
| » Lost to Yankees (6-0), 7-5 | Fenway Park (0-1) | 2-4 | |
| » Starters: Red Ruffing vs Bob Weiland | Fifth | 4 out |
| Saturday, April 22 |
| » Lost to Yankees (7-0), 2-1 | Fenway Park (0-2) | 2-5 | Lost 2 |
| » Starters: George Pipgras vs Gordon Rhodes | Seventh | 5 out |
| Sunday, April 23 |
| » Defeated Athletics (3-7), 7-5 | Fenway Park (1-2) | 3-5 | |
| » Starters: Rube Walberg vs Hank Johnson | Sixth | 4 out |
| Monday, April 24 |
| » Lost to Athletics (4-7), 16-10 | Fenway Park (1-3) | 3-6 | |
| » Starters: George Earnshaw vs Ivy Andrews | Sixth | 4 out |
| Tuesday, April 25 |
| » Defeated Athletics (4-8), 6-4 | Fenway Park (2-3) | 4-6 | |
| » Starters: Lefty Grove vs Bob Weiland | Sixth | 4 out |
| Thursday, April 27 |
| » Lost to Senators (7-6), 3-2 | Fenway Park (2-4) | 4-7 | |
| » Starters: Ed Linke vs Gordon Rhodes | Fifth | 5 out |
| » Major-league debuts: Ed Linke (Senators) |
| Friday, April 28 |
| » Lost to Athletics (5-9), 9-8 | Shibe Park (0-1) | 4-8 | Lost 2 |
| » Starters: Johnny Welch vs Tony Freitas | Sixth | 5 out |
| Saturday, April 29 |
| » Lost to Athletics (6-9), 8-3 | Shibe Park (0-2) | 4-9 | Lost 3 |
| » Starters: Hank Johnson vs Lefty Grove | Sixth | 5 out |
| Sunday, April 30 |
| » Lost to Yankees (10-4), 11-2 | Yankee Stadium (0-3) | 4-10 | Lost 4 |
| » Starters: Bob Kline vs Russ Van Atta | Seventh | 7 out |
| » Lost to Yankees (11-4), 8-3 | Yankee Stadium (0-4) | 4-11 | Lost 5 |
| » Starters: Bob Weiland vs Don Brennan | Seventh | 7 out |
| Tuesday, May 2 |
| » Lost to Browns (7-12), 2-1 | Sportsman's Park III (0-1) | 4-12 | Lost 6 |
| » Starters: Gordon Rhodes vs George Blaeholder | Seventh | 7 out |
| Wednesday, May 3 |
| » Defeated Browns (7-13), 6-2 | Sportsman's Park III (1-1) | 5-12 | |
| » Starters: Ivy Andrews vs Bump Hadley | Seventh | 6½ out |
| Sunday, May 7 |
| » Lost to White Sox (12-7), 4-3 | Comiskey Park I (0-1) | 5-13 | |
| » Starters: Gordon Rhodes vs Milt Gaston | Seventh | 6½ out |
| » Defeated White Sox (12-8), 3-2 | Comiskey Park I (1-1) | 6-13 | |
| » Starters: Hank Johnson vs Paul Gregory | Seventh | 6½ out |
| Wednesday, May 10 |
| » Lost to Indians (14-8), 4-2 | Cleveland Stadium (0-1) | 6-14 | |
| » Starters: Bob Weiland vs Willis Hudlin | Seventh | 7 out |
| Thursday, May 11 |
| » Lost to Indians (15-8), 4-1 | Cleveland Stadium (0-2) | 6-15 | Lost 2 |
| » Starters: Ivy Andrews vs Mel Harder | Eighth | 8 out |
| Sunday, May 14 |
| » Defeated Tigers (10-14), 6-1 | Tiger Stadium (1-0) | 7-15 | |
| » Starters: Gordon Rhodes vs Tommy Bridges | Eighth | 8½ out |
| » Lost to Tigers (11-14), 3-2 | Tiger Stadium (1-1) | 7-16 | |
| » Starters: Hank Johnson vs Firpo Marberry | Eighth | 8½ out |
| Tuesday, May 16 |
| » Lost to Browns (11-17), 3-2 | Fenway Park (2-5) | 7-17 | Lost 2 |
| » Starters: Bump Hadley vs Lloyd Brown | Seventh | 8 out |
| Wednesday, May 17 |
| » Defeated Browns (11-18), 7-3 | Fenway Park (3-5) | 8-17 | |
| » Starters: George Blaeholder vs George Pipgras | Eighth | 8 out |
| Thursday, May 18 |
| » Lost to Browns (12-18), 8-2 | Fenway Park (3-6) | 8-18 | |
| » Starters: Dick Coffman vs Bob Weiland | Seventh | 9 out |
| Future Red Sox Carroll Hardy is born in Sturgis, SD. |
| Friday, May 19 |
| » Lost to Tigers (12-16), 7-5 | Fenway Park (3-7) | 8-19 | Lost 2 |
| » Starters: Firpo Marberry vs Gordon Rhodes | Seventh | 10 out |
| Saturday, May 20 |
| » Defeated Tigers (12-17), 6-5 | Fenway Park (4-7) | 9-19 | |
| » Starters: Tommy Bridges vs Hank Johnson | Eighth | 9 out |
| Sunday, May 21 |
| » Defeated Tigers (12-18), 2-0 | Fenway Park (5-7) | 10-19 | Won 2 |
| » Starters: Vic Sorrell vs Lloyd Brown | Eighth | 8 out |
| Monday, May 22 |
| » Defeated White Sox (17-14), 3-2 | Fenway Park (6-7) | 11-19 | Won 3 |
| » Starters: Ed Durham vs George Pipgras | Eighth | 8 out |
| Tuesday, May 23 |
| » Lost to White Sox (18-14), 7-0 | Fenway Park (6-8) | 11-20 | |
| » Starters: Milt Gaston vs Ivy Andrews | Eighth | 9 out |
| Thursday, May 25 |
| » Lost to Indians (19-16), 3-2 | Fenway Park (6-9) | 11-21 | Lost 2 |
| » Starters: Mel Harder vs Gordon Rhodes | Seventh | 9½ out |
| Friday, May 26 |
| » Defeated Indians (19-17), 6-5 | Fenway Park (7-9) | 12-21 | |
| » Starters: Clint Brown vs Hank Johnson | Eighth | 8½ out |
| Saturday, May 27 |
| » Lost to Indians (20-17), 6-0 | Fenway Park (7-10) | 12-22 | |
| » Starters: Wes Ferrell vs Lloyd Brown | Seventh | 9½ out |
| Sunday, May 28 |
| » Defeated Indians (20-18), 5-2 | Fenway Park (8-10) | 13-22 | |
| » Starters: Oral Hildebrand vs Bob Weiland | Eighth | 10½ out |
| » Lost to Indians (21-18), 11-2 | Fenway Park (8-11) | 13-23 | |
| » Starters: Willis Hudlin vs Ivy Andrews | Eighth | 10½ out |
| Tuesday, May 30 |
| » Lost to Athletics (20-16), 7-3 | Fenway Park (8-12) | 13-24 | Lost 2 |
| » Starters: Sugar Cain vs George Pipgras | Eighth | 12 out |
| » Lost to Athletics (21-16), 11-8 | Fenway Park (8-13) | 13-25 | Lost 3 |
| » Starters: George Earnshaw vs Gordon Rhodes | Eighth | 12 out |
| Thursday, June 1 |
| » Defeated Senators (24-19), 7-5 | Griffith Stadium (3-1) | 14-25 | |
| » Starters: Hank Johnson vs Bill McAfee | Eighth | 11½ out |
| Friday, June 2 |
| » Lost to Senators (25-19), 8-3 | Griffith Stadium (3-2) | 14-26 | |
| » Starters: Bob Weiland vs Monte Weaver | Seventh | 12½ out |
| Saturday, June 3 |
| » Lost to Senators (26-19), 8-5 | Griffith Stadium (3-3) | 14-27 | Lost 2 |
| » Starters: Lloyd Brown vs Earl Whitehill | Eighth | 13½ out |
| Sunday, June 4 |
| » Lost to Senators (27-19), 4-3 | Griffith Stadium (3-4) | 14-28 | Lost 3 |
| » Starters: George Pipgras vs Tommy Thomas | Eighth | 15 out |
| Future Red Sox Arnie Earley is born in Lincoln Park, MI. |
| Tuesday, June 6 |
| » Lost to Yankees (30-13), 4-0 | Yankee Stadium (0-5) | 14-29 | Lost 4 |
| » Starters: Hank Johnson vs Herb Pennock | Eighth | 17 out |
| » Lost to Yankees (31-13), 8-4 | Yankee Stadium (0-6) | 14-30 | Lost 5 |
| » Starters: Gordon Rhodes vs Don Brennan | Eighth | 17 out |
| Thursday, June 8 |
| » Defeated Senators (27-22), 4-3 | Fenway Park (9-13) | 15-30 | |
| » Starters: Tommy Thomas vs Lloyd Brown | Eighth | 16½ out |
| » Lost to Senators (28-22), 12-3 | Fenway Park (9-14) | 15-31 | |
| » Starters: Jack Russell vs Johnny Welch | Eighth | 16½ out |
| Friday, June 9 |
| » Lost to Senators (29-22), 7-2 | Fenway Park (9-15) | 15-32 | Lost 2 |
| » Starters: Earl Whitehill vs George Pipgras | Eighth | 17½ out |
| Saturday, June 10 |
| » Lost to Senators (30-22), 7-5 | Fenway Park (9-16) | 15-33 | Lost 3 |
| » Starters: Lefty Stewart vs Hank Johnson | Eighth | 17 out |
| Former Red Sox Jack O'Brien dies in Watervliet, NY at the age of 61. |
| Sunday, June 11 |
| » Lost to Yankees (33-16), 8-7 | Fenway Park (9-17) | 15-34 | Lost 4 |
| » Starters: Don Brennan vs Gordon Rhodes | Eighth | 17 out |
| » Defeated Yankees (33-17), 11-9 | Fenway Park (10-17) | 16-34 | |
| » Starters: Red Ruffing vs Bob Kline | Eighth | 17 out |
| Tuesday, June 13 |
| » Defeated Yankees (33-18), 6-5 | Fenway Park (11-17) | 17-34 | Won 2 |
| » Starters: Danny MacFayden vs Lloyd Brown | Eighth | 16 out |
| Wednesday, June 14 |
| » Defeated Yankees (33-19), 13-5 | Fenway Park (12-17) | 18-34 | Won 3 |
| » Starters: Lefty Gomez vs George Pipgras | Eighth | 15 out |
| Thursday, June 15 |
| » Defeated Yankees (33-20), 8-5 | Fenway Park (13-17) | 19-34 | Won 4 |
| » Starters: Johnny Allen vs Hank Johnson | Seventh | 14 out |
| Saturday, June 17 |
| » Lost to Athletics (27-23), 15-3 | Fenway Park (13-18) | 19-35 | |
| » Starters: George Earnshaw vs Ivy Andrews | Seventh | 14½ out |
| » Defeated Athletics (27-24), 7-5 | Fenway Park (14-18) | 20-35 | |
| » Starters: Sugar Cain vs Gordon Rhodes | Seventh | 14½ out |
| Sunday, June 18 |
| » Lost to Indians (31-26), 7-0 | Cleveland Stadium (0-3) | 20-36 | |
| » Starters: Lloyd Brown vs Oral Hildebrand | Eighth | 15½ out |
| » Lost to Indians (32-26), 4-0 | Cleveland Stadium (0-4) | 20-37 | Lost 2 |
| » Starters: Bob Weiland vs Mel Harder | Eighth | 15½ out |
| Monday, June 19 |
| » Defeated Indians (32-27), 5-2 | Cleveland Stadium (1-4) | 21-37 | |
| » Starters: George Pipgras vs Clint Brown | Seventh | 14½ out |
| Tuesday, June 20 |
| » Defeated Indians (32-28), 9-5 | Cleveland Stadium (2-4) | 22-37 | Won 2 |
| » Starters: Hank Johnson vs Sarge Connally | Seventh | 14½ out |
| Wednesday, June 21 |
| » Defeated Tigers (29-31), 10-9 | Tiger Stadium (2-1) | 23-37 | Won 3 |
| » Starters: Gordon Rhodes vs Art Herring | Seventh | 15 out |
| » Lost to Tigers (30-31), 5-3 | Tiger Stadium (2-2) | 23-38 | |
| » Starters: Ivy Andrews vs Firpo Marberry | Seventh | 15 out |
| Thursday, June 22 |
| » Defeated Tigers (30-32), 9-7 | Tiger Stadium (3-2) | 24-38 | |
| » Starters: Lloyd Brown vs Vic Sorrell | Sixth | 14 out |
| Friday, June 23 |
| » Defeated Tigers (30-33), 3-2 | Tiger Stadium (4-2) | 25-38 | Won 2 |
| » Starters: Bob Weiland vs Schoolboy Rowe | Seventh | 14 out |
| Saturday, June 24 |
| » Lost to Tigers (31-33), 16-4 | Tiger Stadium (4-3) | 25-39 | |
| » Starters: George Pipgras vs Vic Frasier | Seventh | 15 out |
| Sunday, June 25 |
| » Lost to Browns (24-42), 10-6 | Sportsman's Park III (1-2) | 25-40 | Lost 2 |
| » Starters: Hank Johnson vs Bump Hadley | Seventh | 17 out |
| » Lost to Browns (25-42), 6-4 | Sportsman's Park III (1-3) | 25-41 | Lost 3 |
| » Starters: Lloyd Brown vs George Blaeholder | Seventh | 17 out |
| Monday, June 26 |
| » Defeated Browns (25-43), 13-5 | Sportsman's Park III (2-3) | 26-41 | |
| » Starters: Gordon Rhodes vs Hank McDonald | Sixth | 17 out |
| Tuesday, June 27 |
| » Defeated Browns (25-44), 5-4 | Sportsman's Park III (3-3) | 27-41 | Won 2 |
| » Starters: Ivy Andrews vs Sam Gray | Seventh | 16 out |
| Friday, June 30 |
| » Defeated White Sox (34-35), 4-2 | Comiskey Park I (2-1) | 28-41 | Won 3 |
| » Starters: Hank Johnson vs Ted Lyons | Seventh | 16 out |
| Saturday, July 1 |
| » Defeated White Sox (34-36), 7-2 | Comiskey Park I (3-1) | 29-41 | Won 4 |
| » Starters: George Pipgras vs Paul Gregory | Seventh | 16 out |
| Future Red Sox Frank Baumann is born in St. Louis, MO. |
| Tuesday, July 4 |
| » Defeated Athletics (36-35), 14-4 | Shibe Park (1-2) | 30-41 | Won 5 |
| » Starters: Gordon Rhodes vs Rube Walberg | Seventh | 16 out |
| » Defeated Athletics (36-36), 9-1 | Shibe Park (2-2) | 31-41 | Won 6 |
| » Starters: Ivy Andrews vs George Earnshaw | Seventh | 16 out |
| Wednesday, July 5 |
| » Lost to Athletics (37-36), 4-2 | Shibe Park (2-3) | 31-42 | |
| » Starters: Bob Weiland vs Dick Barrett | Seventh | 16½ out |
| Saturday, July 8 |
| » Lost to Browns (30-50), 4-1 | Fenway Park (14-19) | 31-43 | Lost 2 |
| » Starters: Ed Wells vs Hank Johnson | Sixth | 18 out |
| Sunday, July 9 |
| » Defeated Browns (30-51), 4-0 | Fenway Park (15-19) | 32-43 | |
| » Starters: Bump Hadley vs George Pipgras | Seventh | 18½ out |
| » Lost to Browns (31-51), 9-2 | Fenway Park (15-20) | 32-44 | |
| » Starters: George Blaeholder vs Gordon Rhodes | Seventh | 18½ out |
| Monday, July 10 |
| » Lost to Browns (32-51), 9-5 | Fenway Park (15-21) | 32-45 | Lost 2 |
| » Starters: Rollie Stiles vs Ivy Andrews | Seventh | 18½ out |
| Tuesday, July 11 |
| » Defeated Tigers (38-43), 2-1 | Fenway Park (16-21) | 33-45 | |
| » Starters: Vic Frasier vs Bob Weiland | Seventh | 17½ out |
| Wednesday, July 12 |
| » Defeated Tigers (38-44), 1-0 | Fenway Park (17-21) | 34-45 | Won 2 |
| » Starters: Vic Sorrell vs Lloyd Brown | Seventh | 17½ out |
| Thursday, July 13 |
| » Lost to Tigers (39-44), 3-2 | Fenway Park (17-22) | 34-46 | |
| » Starters: Firpo Marberry vs Hank Johnson | Seventh | 17½ out |
| Friday, July 14 |
| » Lost to Tigers (40-44), 8-3 | Fenway Park (17-23) | 34-47 | Lost 2 |
| » Starters: Tommy Bridges vs George Pipgras | Seventh | 17½ out |
| Saturday, July 15 |
| » Defeated Indians (39-47), 7-2 | Fenway Park (18-23) | 35-47 | |
| » Starters: Mel Harder vs Gordon Rhodes | Seventh | 18 out |
| Sunday, July 16 |
| » Lost to Indians (40-47), 2-1 | Fenway Park (18-24) | 35-48 | |
| » Starters: Willis Hudlin vs Bob Weiland | Sixth | 18 out |
| Tuesday, July 18 |
| » Lost to Indians (41-47), 2-1 | Fenway Park (18-25) | 35-49 | Lost 2 |
| » Starters: Monte Pearson vs Lloyd Brown | Seventh | 19 out |
| Wednesday, July 19 |
| » Lost to Indians (42-47), 8-7 | Fenway Park (18-26) | 35-50 | Lost 3 |
| » Starters: Wes Ferrell vs Hank Johnson | Sixth | 19 out |
| Thursday, July 20 |
| » Defeated White Sox (43-44), 5-0 | Fenway Park (19-26) | 36-50 | |
| » Starters: Ed Durham vs George Pipgras | Sixth | 18 out |
| Friday, July 21 |
| » Defeated White Sox (43-45), 12-2 | Fenway Park (20-26) | 37-50 | Won 2 |
| » Starters: Milt Gaston vs Gordon Rhodes | Sixth | 18 out |
| Saturday, July 22 |
| » Defeated White Sox (43-46), 5-3 | Fenway Park (21-26) | 38-50 | Won 3 |
| » Starters: Jake Miller vs Bob Kline | Seventh | 18 out |
| Sunday, July 23 |
| » Defeated White Sox (43-47), 6-2 | Fenway Park (22-26) | 39-50 | Won 4 |
| » Starters: Ted Lyons vs Hank Johnson | Seventh | 17 out |
| » Defeated White Sox (43-48), 7-2 | Fenway Park (23-26) | 40-50 | Won 5 |
| » Starters: Chad Kimsey vs George Pipgras | Seventh | 17 out |
| Former Red Sox Rip Williams dies in Keokuk, IA at the age of 52. |
| Wednesday, July 26 |
| » Lost to Yankees (58-33), 2-0 | Fenway Park (23-27) | 40-51 | |
| » Starters: Lefty Gomez vs Bob Weiland | Seventh | 18 out |
| » Defeated Yankees (58-34), 9-4 | Fenway Park (24-27) | 41-51 | |
| » Starters: Jumbo Brown vs Lloyd Brown | Seventh | 18 out |
| Future Red Sox Norm Siebern is born in St. Louis, MO. |
| Thursday, July 27 |
| » Defeated Athletics (47-47), 6-2 | Fenway Park (25-27) | 42-51 | Won 2 |
| » Starters: Sugar Cain vs Gordon Rhodes | Seventh | 18 out |
| Saturday, July 29 |
| » Defeated Athletics (47-48), 8-1 | Fenway Park (26-27) | 43-51 | Won 3 |
| » Starters: Lefty Grove vs George Pipgras | Sixth | 18 out |
| Sunday, July 30 |
| » Defeated Athletics (47-49), 8-3 | Fenway Park (27-27) | 44-51 | Won 4 |
| » Starters: George Earnshaw vs Bob Kline | Seventh | 17 out |
| Wednesday, August 2 |
| » Lost to Senators (62-35), 2-1 | Griffith Stadium (3-5) | 44-52 | |
| » Starters: Bob Weiland vs General Crowder | Seventh | 17½ out |
| Thursday, August 3 |
| » Lost to Senators (63-35), 8-4 | Griffith Stadium (3-6) | 44-53 | Lost 2 |
| » Starters: Johnny Welch vs Earl Whitehill | Seventh | 18½ out |
| Saturday, August 5 |
| » Lost to Senators (64-35), 3-2 | Griffith Stadium (3-7) | 44-54 | Lost 3 |
| » Starters: Gordon Rhodes vs Monte Weaver | Seventh | 19½ out |
| Sunday, August 6 |
| » Lost to Yankees (61-39), 5-4 | Yankee Stadium (0-7) | 44-55 | Lost 4 |
| » Starters: George Pipgras vs Danny MacFayden | Seventh | 19½ out |
| Monday, August 7 |
| » Defeated Athletics (51-50), 8-5 | Shibe Park (3-3) | 45-55 | |
| » Starters: Bob Weiland vs George Earnshaw | Seventh | 18 out |
| Tuesday, August 8 |
| » Lost to Athletics (52-50), 7-6 | Shibe Park (3-4) | 45-56 | |
| » Starters: George Pipgras vs Lefty Grove | Seventh | 19 out |
| Wednesday, August 9 |
| » Defeated Athletics (52-51), 8-4 | Shibe Park (4-4) | 46-56 | |
| » Starters: Lloyd Brown vs Dick Barrett | Seventh | 19 out |
| Thursday, August 10 |
| » Lost to Senators (67-38), 5-3 | Fenway Park (27-28) | 46-57 | |
| » Starters: General Crowder vs Gordon Rhodes | Seventh | 20 out |
| Former Red Sox Elliot Bigelow dies in Tampa, FL at the age of 36. |
| Friday, August 11 |
| » Lost to Senators (68-38), 8-4 | Fenway Park (27-29) | 46-58 | Lost 2 |
| » Starters: Tommy Thomas vs Hank Johnson | Seventh | 21 out |
| Saturday, August 12 |
| » Lost to Senators (69-38), 2-1 | Fenway Park (27-30) | 46-59 | Lost 3 |
| » Starters: Earl Whitehill vs Bob Weiland | Seventh | 22 out |
| Sunday, August 13 |
| » Defeated Athletics (53-53), 19-10 | Fenway Park (28-30) | 47-59 | |
| » Starters: Sugar Cain vs Gordon Rhodes | Seventh | 22 out |
| Monday, August 14 |
| » Lost to Tigers (54-57), 6-5 | Tiger Stadium (4-4) | 47-60 | |
| » Starters: George Pipgras vs Elden Auker | Seventh | 22½ out |
| Tuesday, August 15 |
| » Defeated Tigers (54-58), 5-3 | Tiger Stadium (5-4) | 48-60 | |
| » Starters: Hank Johnson vs Firpo Marberry | Seventh | 22½ out |
| Wednesday, August 16 |
| » Lost to Tigers (55-58), 6-5 | Tiger Stadium (5-5) | 48-61 | |
| » Starters: Lloyd Brown vs Vic Frasier | Seventh | 23½ out |
| Thursday, August 17 |
| » Defeated Tigers (55-59), 6-2 | Tiger Stadium (6-5) | 49-61 | |
| » Starters: Bob Weiland vs Elden Auker | Seventh | 23½ out |
| Friday, August 18 |
| » Lost to Indians (58-59), 2-1 | Cleveland Stadium (2-5) | 49-62 | |
| » Starters: Gordon Rhodes vs Mel Harder | Seventh | 24½ out |
| Saturday, August 19 |
| » Lost to Indians (59-59), 6-5 | Cleveland Stadium (2-6) | 49-63 | Lost 2 |
| » Starters: Ivy Andrews vs Clint Brown | Seventh | 25½ out |
| Sunday, August 20 |
| » Lost to Indians (60-59), 14-6 | Cleveland Stadium (2-7) | 49-64 | Lost 3 |
| » Starters: Hank Johnson vs Oral Hildebrand | Seventh | 27½ out |
| » Lost to Indians (61-59), 9-4 | Cleveland Stadium (2-8) | 49-65 | Lost 4 |
| » Starters: Bob Kline vs Wes Ferrell | Seventh | 27½ out |
| Monday, August 21 |
| » Lost to Indians (62-59), 10-1 | Cleveland Stadium (2-9) | 49-66 | Lost 5 |
| » Starters: Bob Weiland vs Monte Pearson | Seventh | 28 out |
| Tuesday, August 22 |
| » Lost to White Sox (53-63), 8-1 | Comiskey Park I (3-2) | 49-67 | Lost 6 |
| » Starters: Gordon Rhodes vs Ted Lyons | Seventh | 28½ out |
| » Lost to White Sox (54-63), 4-0 | Comiskey Park I (3-3) | 49-68 | Lost 7 |
| » Starters: Lloyd Brown vs Joe Heving | Seventh | 28½ out |
| Wednesday, August 23 |
| » Lost to White Sox (55-63), 3-1 | Comiskey Park I (3-4) | 49-69 | Lost 8 |
| » Starters: Bob Kline vs Sad Sam Jones | Seventh | 29½ out |
| » Lost to White Sox (56-63), 12-1 | Comiskey Park I (3-5) | 49-70 | Lost 9 |
| » Starters: Curt Fullerton vs Ed Durham | Seventh | 29½ out |
| Thursday, August 24 |
| » Defeated White Sox (56-64), 6-1 | Comiskey Park I (4-5) | 50-70 | |
| » Starters: Johnny Welch vs Whit Wyatt | Seventh | 30 out |
| » Lost to White Sox (57-64), 7-6 | Comiskey Park I (4-6) | 50-71 | |
| » Starters: Bob Weiland vs Jake Miller | Seventh | 30 out |
| Friday, August 25 |
| » Defeated White Sox (57-65), 8-1 | Comiskey Park I (5-6) | 51-71 | |
| » Starters: Gordon Rhodes vs Milt Gaston | Seventh | 30 out |
| Saturday, August 26 |
| » Defeated Browns (45-80), 8-1 | Sportsman's Park III (4-3) | 52-71 | Won 2 |
| » Starters: Lloyd Brown vs George Blaeholder | Seventh | 29 out |
| Sunday, August 27 |
| » Defeated Browns (45-81), 7-5 | Sportsman's Park III (5-3) | 53-71 | Won 3 |
| » Starters: Bob Kline vs Bump Hadley | Seventh | 29 out |
| » Lost to Browns (46-81), 5-3 | Sportsman's Park III (5-4) | 53-72 | |
| » Starters: Curt Fullerton vs Jack Knott | Seventh | 29 out |
| Tuesday, August 29 |
| » Lost to Browns (47-81), 10-8 | Sportsman's Park III (5-5) | 53-73 | Lost 2 |
| » Starters: Johnny Welch vs Sam Gray | Seventh | 29 out |
| » Defeated Browns (47-82), 9-4 | Sportsman's Park III (6-5) | 54-73 | |
| » Starters: Bob Weiland vs George Blaeholder | Seventh | 29 out |
| Thursday, August 31 |
| » Defeated Yankees (73-51), 15-2 | Yankee Stadium (1-7) | 55-73 | Won 2 |
| » Starters: Gordon Rhodes vs Herb Pennock | Seventh | 28½ out |
| Friday, September 1 |
| » Defeated Yankees (73-52), 4-2 | Yankee Stadium (2-7) | 56-73 | Won 3 |
| » Starters: Lloyd Brown vs Red Ruffing | Seventh | 27½ out |
| Saturday, September 2 |
| » Lost to Yankees (74-52), 2-1 | Yankee Stadium (2-8) | 56-74 | |
| » Starters: Bob Weiland vs Johnny Allen | Seventh | 28 out |
| Sunday, September 3 |
| » Lost to Senators (84-45), 3-2 | Griffith Stadium (3-8) | 56-75 | Lost 2 |
| » Starters: Ivy Andrews vs Monte Weaver | Seventh | 29 out |
| Tuesday, September 5 |
| » Lost to Senators (85-45), 5-4 | Fenway Park (28-31) | 56-76 | Lost 3 |
| » Starters: Lefty Stewart vs Gordon Rhodes | Seventh | 31 out |
| » Lost to Senators (86-45), 9-6 | Fenway Park (28-32) | 56-77 | Lost 4 |
| » Starters: Earl Whitehill vs Johnny Welch | Seventh | 31 out |
| Wednesday, September 6 |
| » Lost to Tigers (66-68), 11-5 | Fenway Park (28-33) | 56-78 | Lost 5 |
| » Starters: Roxie Lawson vs Lloyd Brown | Seventh | 32 out |
| Friday, September 8 |
| » Lost to Tigers (67-68), 4-3 | Fenway Park (28-34) | 56-79 | Lost 6 |
| » Starters: Tommy Bridges vs Ivy Andrews | Seventh | 33 out |
| » Lost to Tigers (68-68), 4-3 | Fenway Park (28-35) | 56-80 | Lost 7 |
| » Starters: Firpo Marberry vs Bob Weiland | Seventh | 33 out |
| » Major-league debuts: Mel Almada (Red Sox) |
| Saturday, September 9 |
| » Defeated Tigers (68-69), 6-4 | Fenway Park (29-35) | 57-80 | |
| » Starters: Vic Sorrell vs Gordon Rhodes | Seventh | 33 out |
| Sunday, September 10 |
| » Lost to Browns (50-87), 3-2 | Fenway Park (29-36) | 57-81 | |
| » Starters: Bump Hadley vs Bob Weiland | Seventh | 34½ out |
| » Lost to Browns (51-87), 4-0 | Fenway Park (29-37) | 57-82 | Lost 2 |
| » Starters: George Blaeholder vs Johnny Welch | Seventh | 34½ out |
| Tuesday, September 12 |
| » Lost to Browns (52-87), 4-1 | Fenway Park (29-38) | 57-83 | Lost 3 |
| » Starters: Dick Coffman vs Ivy Andrews | Seventh | 35 out |
| Wednesday, September 13 |
| » Defeated Browns (52-88), 3-1 | Fenway Park (30-38) | 58-83 | |
| » Starters: Jack Knott vs Lloyd Brown | Seventh | 34½ out |
| Monday, September 18 |
| » Lost to Indians (74-71), 9-0 | Fenway Park (30-39) | 58-84 | |
| » Starters: Oral Hildebrand vs Gordon Rhodes | Seventh | 36½ out |
| Tuesday, September 19 |
| » Defeated Indians (74-72), 4-3 | Fenway Park (31-39) | 59-84 | |
| » Starters: Clint Brown vs Bob Weiland | Seventh | 35½ out |
| » Major-league debuts: Thornton Lee (Indians) |
| Thursday, September 21 |
| » Major-league debuts: Frankie Hayes (Athletics) |
| Saturday, September 23 |
| » Lost to Yankees (88-55), 16-12 | Fenway Park (31-40) | 59-85 | |
| » Starters: Herb Pennock vs Lloyd Brown | Seventh | 36½ out |
| Sunday, September 24 |
| » Defeated Yankees (88-56), 10-8 | Fenway Park (32-40) | 60-85 | |
| » Starters: Charlie Devens vs Bob Weiland | Seventh | 35½ out |
| Wednesday, September 27 |
| Future Red Sox Jerry Casale is born in Brooklyn, NY. |
| Thursday, September 28 |
| » Defeated Athletics (78-70), 4-3 | Shibe Park (5-4) | 61-85 | Won 2 |
| » Starters: Lloyd Brown vs Jim Peterson | Seventh | 34½ out |
| Saturday, September 30 |
| » Defeated Athletics (78-71), 2-1 | Shibe Park (6-4) | 62-85 | Won 3 |
| » Starters: Bob Weiland vs Bill Dietrich | Seventh | 34½ out |
| » Defeated Athletics (78-72), 12-1 | Shibe Park (7-4) | 63-85 | Won 4 |
| » Starters: Ivy Andrews vs Emil Roy | Seventh | 34½ out |
| Sunday, October 1 |
| » Lost to Yankees (91-59), 6-5 | Yankee Stadium (2-9) | 63-86 | |
| » Starters: Bob Kline vs Babe Ruth | Seventh | 34½ out |
| Sunday, October 22 |
| Future Red Sox Ron Jackson is born in Kalamazoo, MI. |
| Friday, October 27 |
| Future Red Sox Pumpsie Green is born in Oakland, CA. |
| Friday, November 17 |
| Future Red Sox Dan Osinski is born in Chicago, IL. |
Game information provided by Retrosheet (www.retrosheet.org) |