| Wednesday, April 12 |
| » Lost to Senators (1-0), 4-1 | Griffith Stadium (0-1) | 0-1 | |
| » Starters: Tony Freitas vs General Crowder | Third | 1 out |
| Thursday, April 13 |
| » Lost to Senators (2-0), 11-4 | Griffith Stadium (0-2) | 0-2 | Lost 2 |
| » Starters: George Earnshaw vs Earl Whitehill | Fourth | 2 out |
| Friday, April 14 |
| » Defeated Senators (2-1), 5-1 | Griffith Stadium (1-2) | 1-2 | |
| » Starters: Lefty Grove vs Lefty Stewart | Third | 1½ out |
| Saturday, April 15 |
| » Lost to Yankees (3-0), 7-3 | Yankee Stadium (0-1) | 1-3 | |
| » Starters: Sugar Cain vs George Pipgras | Sixth | 2½ out |
| Sunday, April 16 |
| » Lost to Yankees (4-0), 5-4 | Yankee Stadium (0-2) | 1-4 | Lost 2 |
| » Starters: Rube Walberg vs Don Brennan | Sixth | 3½ out |
| » Major-league debuts: Don Brennan (Yankees) |
| Tuesday, April 18 |
| » Lost to Yankees (5-0), 2-1 | Yankee Stadium (0-3) | 1-5 | Lost 3 |
| » Starters: George Earnshaw vs Lefty Gomez | Fifth | 4½ out |
| Thursday, April 20 |
| » Defeated Senators (3-4), 8-1 | Shibe Park (1-0) | 2-5 | |
| » Starters: Lefty Stewart vs Lefty Grove | Seventh | 4 out |
| Friday, April 21 |
| » Defeated Senators (3-5), 3-1 | Shibe Park (2-0) | 3-5 | Won 2 |
| » Starters: General Crowder vs Sugar Cain | Fourth | 4 out |
| Saturday, April 22 |
| » Lost to Senators (4-5), 10-7 | Shibe Park (2-1) | 3-6 | |
| » Starters: Monte Weaver vs Tony Freitas | Sixth | 5 out |
| Sunday, April 23 |
| » Lost to Red Sox (3-5), 7-5 | Fenway Park (0-1) | 3-7 | Lost 2 |
| » Starters: Rube Walberg vs Hank Johnson | Seventh | 5 out |
| Monday, April 24 |
| » Defeated Red Sox (3-6), 16-10 | Fenway Park (1-1) | 4-7 | |
| » Starters: George Earnshaw vs Ivy Andrews | Fifth | 4 out |
| Tuesday, April 25 |
| » Lost to Red Sox (4-6), 6-4 | Fenway Park (1-2) | 4-8 | |
| » Starters: Lefty Grove vs Bob Weiland | Seventh | 5 out |
| Thursday, April 27 |
| » Lost to Yankees (9-2), 5-2 | Shibe Park (2-2) | 4-9 | Lost 2 |
| » Starters: Red Ruffing vs Sugar Cain | Sixth | 6 out |
| Friday, April 28 |
| » Defeated Red Sox (4-8), 9-8 | Shibe Park (3-2) | 5-9 | |
| » Starters: Johnny Welch vs Tony Freitas | Fifth | 5 out |
| Saturday, April 29 |
| » Defeated Red Sox (4-9), 8-3 | Shibe Park (4-2) | 6-9 | Won 2 |
| » Starters: Hank Johnson vs Lefty Grove | Fourth | 4 out |
| Sunday, April 30 |
| » Lost to Senators (10-6), 5-4 | Griffith Stadium (1-3) | 6-10 | |
| » Starters: Rube Walberg vs General Crowder | Fifth | 5½ out |
| Thursday, May 4 |
| » Lost to White Sox (11-7), 2-1 | Comiskey Park I (0-1) | 6-11 | Lost 2 |
| » Starters: Sugar Cain vs Sad Sam Jones | Fifth | 6 out |
| Saturday, May 6 |
| » Defeated Browns (7-14), 8-6 | Sportsman's Park III (1-0) | 7-11 | |
| » Starters: Lefty Grove vs Lloyd Brown | Fifth | 5 out |
| Wednesday, May 10 |
| » Defeated Tigers (10-12), 3-2 | Tiger Stadium (1-0) | 8-11 | Won 2 |
| » Starters: Sugar Cain vs Firpo Marberry | Fourth | 4 out |
| » Defeated Tigers (10-13), 6-4 | Tiger Stadium (2-0) | 9-11 | Won 3 |
| » Starters: Rube Walberg vs Vic Sorrell | Fourth | 4 out |
| Friday, May 12 |
| » Defeated Indians (15-9), 7-3 | Cleveland Stadium (1-0) | 10-11 | Won 4 |
| » Starters: Roy Mahaffey vs Wes Ferrell | Fifth | 3½ out |
| Sunday, May 14 |
| » Lost to Indians (16-9), 3-0 | Cleveland Stadium (1-1) | 10-12 | |
| » Starters: Tony Freitas vs Oral Hildebrand | Sixth | 5½ out |
| » Lost to Indians (17-9), 5-3 | Cleveland Stadium (1-2) | 10-13 | Lost 2 |
| » Starters: Hank McDonald vs Clint Brown | Sixth | 5½ out |
| Monday, May 15 |
| » Defeated Indians (17-10), 1-0 | Shibe Park (5-2) | 11-13 | |
| » Starters: Willis Hudlin vs Sugar Cain | Fifth | 4½ out |
| Tuesday, May 16 |
| » Major-league debuts: Cecil Travis (Senators) |
| Wednesday, May 17 |
| » Lost to White Sox (15-11), 5-2 | Shibe Park (5-3) | 11-14 | |
| » Starters: Ed Durham vs Rube Walberg | Fifth | 5 out |
| Thursday, May 18 |
| » Defeated White Sox (15-12), 9-1 | Shibe Park (6-3) | 12-14 | |
| » Starters: Sad Sam Jones vs George Earnshaw | Fourth | 5 out |
| Friday, May 19 |
| » Defeated Indians (18-13), 9-2 | Shibe Park (7-3) | 13-14 | Won 2 |
| » Starters: Clint Brown vs Roy Mahaffey | Fourth | 5 out |
| Saturday, May 20 |
| » Defeated Indians (18-14), 7-2 | Shibe Park (8-3) | 14-14 | Won 3 |
| » Starters: Willis Hudlin vs Sugar Cain | Fifth | 4 out |
| Monday, May 22 |
| » Defeated Browns (14-20), 6-5 | Shibe Park (9-3) | 15-14 | Won 4 |
| » Starters: George Blaeholder vs Tony Freitas | Fifth | 3½ out |
| Tuesday, May 23 |
| » Defeated Browns (14-21), 8-6 | Shibe Park (10-3) | 16-14 | Won 5 |
| » Starters: Dick Coffman vs Roy Mahaffey | Fourth | 3½ out |
| Wednesday, May 24 |
| » Defeated Browns (14-22), 7-4 | Shibe Park (11-3) | 17-14 | Won 6 |
| » Starters: Bump Hadley vs Sugar Cain | Fourth | 3 out |
| Thursday, May 25 |
| » Defeated Tigers (14-20), 4-3 | Shibe Park (12-3) | 18-14 | Won 7 |
| » Starters: Vic Sorrell vs George Earnshaw | Third | 2½ out |
| Friday, May 26 |
| » Lost to Tigers (15-20), 10-1 | Shibe Park (12-4) | 18-15 | |
| » Starters: Schoolboy Rowe vs Rube Walberg | Fourth | 2½ out |
| Saturday, May 27 |
| » Defeated Tigers (15-21), 5-2 | Shibe Park (13-4) | 19-15 | |
| » Starters: Firpo Marberry vs Tony Freitas | Third | 2½ out |
| Sunday, May 28 |
| » Lost to Senators (23-16), 7-4 | Griffith Stadium (1-4) | 19-16 | |
| » Starters: Rube Walberg vs Lefty Stewart | Third | 4 out |
| Tuesday, May 30 |
| » Defeated Red Sox (13-24), 7-3 | Fenway Park (2-2) | 20-16 | |
| » Starters: Sugar Cain vs George Pipgras | Third | 3½ out |
| » Defeated Red Sox (13-25), 11-8 | Fenway Park (3-2) | 21-16 | Won 2 |
| » Starters: George Earnshaw vs Gordon Rhodes | Third | 3½ out |
| Friday, June 2 |
| » Lost to Yankees (26-13), 5-4 | Yankee Stadium (0-4) | 21-17 | |
| » Starters: Roy Mahaffey vs Lefty Gomez | Third | 4½ out |
| Saturday, June 3 |
| » Lost to Yankees (27-13), 17-11 | Yankee Stadium (0-5) | 21-18 | Lost 2 |
| » Starters: Rube Walberg vs Don Brennan | Fourth | 5½ out |
| Sunday, June 4 |
| » Lost to Yankees (28-13), 3-2 | Yankee Stadium (0-6) | 21-19 | Lost 3 |
| » Starters: Sugar Cain vs Russ Van Atta | Fifth | 7½ out |
| » Lost to Yankees (29-13), 6-0 | Yankee Stadium (0-7) | 21-20 | Lost 4 |
| » Starters: Rube Walberg vs Johnny Allen | Fifth | 7½ out |
| Monday, June 5 |
| » Defeated Senators (27-20), 7-4 | Shibe Park (14-4) | 22-20 | |
| » Starters: General Crowder vs Lefty Grove | Fifth | 7 out |
| Tuesday, June 6 |
| » Defeated Senators (27-21), 8-4 | Shibe Park (15-4) | 23-20 | Won 2 |
| » Starters: Lefty Stewart vs Roy Mahaffey | Fourth | 7½ out |
| Wednesday, June 7 |
| » Tied Senators, 13-13 | Shibe Park (15-4) | 23-20 | |
| » Starters: Earl Whitehill vs Gowell Claset | Fourth | 7½ out |
| Thursday, June 8 |
| » Defeated Yankees (31-14), 14-10 | Shibe Park (16-4) | 24-20 | Won 3 |
| » Starters: Lefty Gomez vs Tony Freitas | Fourth | 6½ out |
| » Major-league debuts: Bobby Coombs (Athletics) |
| Friday, June 9 |
| » Lost to Yankees (32-14), 7-6 | Shibe Park (16-5) | 24-21 | |
| » Starters: Jumbo Brown vs Jim Peterson | Fourth | 7½ out |
| Saturday, June 10 |
| » Defeated Yankees (32-15), 9-5 | Shibe Park (17-5) | 25-21 | |
| » Starters: Russ Van Atta vs Lefty Grove | Third | 5½ out |
| » Defeated Yankees (32-16), 8-7 | Shibe Park (18-5) | 26-21 | Won 2 |
| » Starters: Johnny Allen vs Sugar Cain | Third | 5½ out |
| Sunday, June 11 |
| » Lost to Senators (31-22), 13-6 | Griffith Stadium (1-5) | 26-22 | |
| » Starters: Roy Mahaffey vs General Crowder | Fourth | 6 out |
| Tuesday, June 13 |
| » Lost to Senators (32-22), 10-6 | Griffith Stadium (1-6) | 26-23 | Lost 2 |
| » Starters: Rube Walberg vs Tommy Thomas | Fifth | 6 out |
| Saturday, June 17 |
| » Defeated Red Sox (19-35), 15-3 | Fenway Park (4-2) | 27-23 | |
| » Starters: George Earnshaw vs Ivy Andrews | Fourth | 5½ out |
| » Lost to Red Sox (20-35), 7-5 | Fenway Park (4-3) | 27-24 | |
| » Starters: Sugar Cain vs Gordon Rhodes | Fourth | 5½ out |
| Sunday, June 18 |
| » Lost to Tigers (27-29), 3-2 | Tiger Stadium (2-1) | 27-25 | Lost 2 |
| » Starters: Rube Walberg vs Vic Sorrell | Fifth | 6½ out |
| » Lost to Tigers (28-29), 11-7 | Tiger Stadium (2-2) | 27-26 | Lost 3 |
| » Starters: Roy Mahaffey vs Schoolboy Rowe | Fifth | 6½ out |
| Monday, June 19 |
| » Lost to Tigers (29-29), 9-4 | Tiger Stadium (2-3) | 27-27 | Lost 4 |
| » Starters: Lefty Grove vs Vic Frasier | Fifth | 6½ out |
| Tuesday, June 20 |
| » Defeated Tigers (29-30), 9-4 | Tiger Stadium (3-3) | 28-27 | |
| » Starters: Tony Freitas vs Carl Fischer | Fifth | 6½ out |
| Wednesday, June 21 |
| » Lost to Indians (33-28), 11-1 | Cleveland Stadium (1-3) | 28-28 | |
| » Starters: George Earnshaw vs Wes Ferrell | Fifth | 7½ out |
| Thursday, June 22 |
| » Defeated Indians (33-29), 11-6 | Cleveland Stadium (2-3) | 29-28 | |
| » Starters: Sugar Cain vs Oral Hildebrand | Third | 6½ out |
| Friday, June 23 |
| » Defeated Indians (33-30), 8-4 | Cleveland Stadium (3-3) | 30-28 | Won 2 |
| » Starters: Roy Mahaffey vs Mel Harder | Fourth | 6½ out |
| Saturday, June 24 |
| » Defeated Indians (33-31), 6-2 | Cleveland Stadium (4-3) | 31-28 | Won 3 |
| » Starters: Lefty Grove vs Willis Hudlin | Third | 6½ out |
| Sunday, June 25 |
| » Lost to White Sox (32-32), 3-2 | Comiskey Park I (0-2) | 31-29 | |
| » Starters: George Earnshaw vs Ed Durham | Third | 7½ out |
| » Defeated White Sox (32-33), 5-3 | Comiskey Park I (1-2) | 32-29 | |
| » Starters: Rube Walberg vs Sad Sam Jones | Third | 7½ out |
| Monday, June 26 |
| » Defeated White Sox (32-34), 8-2 | Comiskey Park I (2-2) | 33-29 | Won 2 |
| » Starters: Tony Freitas vs Whit Wyatt | Third | 7½ out |
| Tuesday, June 27 |
| » Lost to White Sox (33-34), 8-3 | Comiskey Park I (2-3) | 33-30 | |
| » Starters: Sugar Cain vs Jake Miller | Third | 7½ out |
| Wednesday, June 28 |
| » Lost to White Sox (34-34), 9-8 | Comiskey Park I (2-4) | 33-31 | Lost 2 |
| » Starters: Roy Mahaffey vs Milt Gaston | Third | 8½ out |
| Thursday, June 29 |
| » Defeated Browns (25-45), 4-1 | Sportsman's Park III (2-0) | 34-31 | |
| » Starters: Lefty Grove vs George Blaeholder | Second | 7½ out |
| Friday, June 30 |
| » Lost to Browns (26-45), 12-11 | Sportsman's Park III (2-1) | 34-32 | |
| » Starters: George Earnshaw vs Ed Wells | Third | 8 out |
| » Defeated Browns (26-46), 11-7 | Sportsman's Park III (3-1) | 35-32 | |
| » Starters: Rube Walberg vs Dick Coffman | Third | 8 out |
| Saturday, July 1 |
| » Lost to Browns (27-46), 15-14 | Sportsman's Park III (3-2) | 35-33 | |
| » Starters: Jim Peterson vs Dick Coffman | Third | 9 out |
| Sunday, July 2 |
| » Defeated Browns (27-47), 6-5 | Sportsman's Park III (4-2) | 36-33 | |
| » Starters: Roy Mahaffey vs Bump Hadley | Third | 9 out |
| » Lost to Browns (28-47), 11-6 | Sportsman's Park III (4-3) | 36-34 | |
| » Starters: Sugar Cain vs George Blaeholder | Third | 9 out |
| Tuesday, July 4 |
| » Lost to Red Sox (30-41), 14-4 | Shibe Park (18-6) | 36-35 | Lost 2 |
| » Starters: Gordon Rhodes vs Rube Walberg | Third | 11 out |
| » Lost to Red Sox (31-41), 9-1 | Shibe Park (18-7) | 36-36 | Lost 3 |
| » Starters: Ivy Andrews vs George Earnshaw | Third | 11 out |
| Wednesday, July 5 |
| » Defeated Red Sox (31-42), 4-2 | Shibe Park (19-7) | 37-36 | |
| » Starters: Bob Weiland vs Dick Barrett | Third | 10½ out |
| Friday, July 7 |
| » Lost to White Sox (37-38), 9-1 | Shibe Park (19-8) | 37-37 | |
| » Starters: Ed Durham vs Roy Mahaffey | Third | 11 out |
| Saturday, July 8 |
| » Defeated White Sox (37-39), 10-4 | Shibe Park (20-8) | 38-37 | |
| » Starters: Ted Lyons vs Sugar Cain | Third | 12 out |
| » Lost to White Sox (38-39), 11-6 | Shibe Park (20-9) | 38-38 | |
| » Starters: Paul Gregory vs George Earnshaw | Third | 12 out |
| Monday, July 10 |
| » Defeated White Sox (38-40), 3-2 | Shibe Park (21-9) | 39-38 | |
| » Starters: Sad Sam Jones vs Lefty Grove | Third | 12 out |
| » Lost to White Sox (39-40), 7-1 | Shibe Park (21-10) | 39-39 | |
| » Starters: Milt Gaston vs Dick Barrett | Third | 12 out |
| Tuesday, July 11 |
| » Defeated Indians (38-44), 6-4 | Shibe Park (22-10) | 40-39 | |
| » Starters: Clint Brown vs Roy Mahaffey | Third | 11 out |
| Wednesday, July 12 |
| » Defeated Indians (38-45), 6-4 | Shibe Park (23-10) | 41-39 | Won 2 |
| » Starters: Oral Hildebrand vs Rube Walberg | Third | 11 out |
| Thursday, July 13 |
| » Lost to Indians (39-45), 6-5 | Shibe Park (23-11) | 41-40 | |
| » Starters: Monte Pearson vs Sugar Cain | Third | 11 out |
| Friday, July 14 |
| » Defeated Indians (39-46), 3-2 | Shibe Park (24-11) | 42-40 | |
| » Starters: Wes Ferrell vs Dick Barrett | Third | 10 out |
| Saturday, July 15 |
| » Defeated Tigers (40-45), 3-2 | Shibe Park (25-11) | 43-40 | Won 2 |
| » Starters: Schoolboy Rowe vs Lefty Grove | Third | 10½ out |
| Tuesday, July 18 |
| » Lost to Tigers (41-45), 5-2 | Shibe Park (25-12) | 43-41 | |
| » Starters: Vic Sorrell vs Rube Walberg | Third | 11 out |
| Wednesday, July 19 |
| » Defeated Tigers (41-46), 7-3 | Shibe Park (26-12) | 44-41 | |
| » Starters: Carl Fischer vs Roy Mahaffey | Second | 10½ out |
| » Lost to Tigers (42-46), 10-5 | Shibe Park (26-13) | 44-42 | |
| » Starters: Firpo Marberry vs Sugar Cain | Second | 10½ out |
| Thursday, July 20 |
| » Defeated Browns (34-59), 6-5 | Shibe Park (27-13) | 45-42 | |
| » Starters: Rollie Stiles vs Lefty Grove | Second | 9½ out |
| Friday, July 21 |
| » Lost to Browns (35-59), 6-3 | Shibe Park (27-14) | 45-43 | |
| » Starters: Bump Hadley vs Roy Mahaffey | Second | 10½ out |
| Saturday, July 22 |
| » Defeated Browns (35-60), 8-7 | Shibe Park (28-14) | 46-43 | |
| » Starters: Hank McDonald vs Rube Walberg | Third | 10 out |
| » Defeated Browns (35-61), 6-5 | Shibe Park (29-14) | 47-43 | Won 2 |
| » Starters: George Blaeholder vs Sugar Cain | Third | 10 out |
| Monday, July 24 |
| » Lost to Senators (57-33), 5-2 | Shibe Park (29-15) | 47-44 | |
| » Starters: Bobby Burke vs Lefty Grove | Third | 11½ out |
| » Lost to Senators (58-33), 10-6 | Shibe Park (29-16) | 47-45 | Lost 2 |
| » Starters: General Crowder vs George Earnshaw | Third | 11½ out |
| Tuesday, July 25 |
| » Lost to Senators (59-33), 5-1 | Shibe Park (29-17) | 47-46 | Lost 3 |
| » Starters: Earl Whitehill vs Roy Mahaffey | Third | 12½ out |
| Thursday, July 27 |
| » Lost to Red Sox (42-51), 6-2 | Fenway Park (4-4) | 47-47 | Lost 4 |
| » Starters: Sugar Cain vs Gordon Rhodes | Third | 13½ out |
| Friday, July 28 |
| » Major-league debuts: Johnny Pasek (Tigers) |
| Saturday, July 29 |
| » Lost to Red Sox (43-51), 8-1 | Fenway Park (4-5) | 47-48 | Lost 5 |
| » Starters: Lefty Grove vs George Pipgras | Third | 14½ out |
| Sunday, July 30 |
| » Lost to Red Sox (44-51), 8-3 | Fenway Park (4-6) | 47-49 | Lost 6 |
| » Starters: George Earnshaw vs Bob Kline | Third | 14½ out |
| Wednesday, August 2 |
| » Defeated Yankees (60-37), 16-3 | Yankee Stadium (1-7) | 48-49 | |
| » Starters: George Earnshaw vs Red Ruffing | Third | 14 out |
| Thursday, August 3 |
| » Defeated Yankees (60-38), 7-0 | Yankee Stadium (2-7) | 49-49 | Won 2 |
| » Starters: Lefty Grove vs Johnny Allen | Third | 14 out |
| Saturday, August 5 |
| » Defeated Yankees (60-39), 8-3 | Yankee Stadium (3-7) | 50-49 | Won 3 |
| » Starters: Roy Mahaffey vs Lefty Gomez | Third | 14 out |
| Sunday, August 6 |
| » Defeated Senators (64-36), 12-8 | Griffith Stadium (2-6) | 51-49 | Won 4 |
| » Starters: Sugar Cain vs Ed Chapman | Third | 13 out |
| Monday, August 7 |
| » Lost to Red Sox (45-55), 8-5 | Shibe Park (29-18) | 51-50 | |
| » Starters: Bob Weiland vs George Earnshaw | Third | 12½ out |
| Tuesday, August 8 |
| » Defeated Red Sox (45-56), 7-6 | Shibe Park (30-18) | 52-50 | |
| » Starters: George Pipgras vs Lefty Grove | Third | 12½ out |
| Wednesday, August 9 |
| » Lost to Red Sox (46-56), 8-4 | Shibe Park (30-19) | 52-51 | |
| » Starters: Lloyd Brown vs Dick Barrett | Third | 13½ out |
| Thursday, August 10 |
| Future Athletic Rocky Colavito is born in New York, NY. |
| Saturday, August 12 |
| » Defeated Yankees (63-42), 11-9 | Shibe Park (31-19) | 53-51 | |
| » Starters: Red Ruffing vs Lefty Grove | Third | 15 out |
| » Lost to Yankees (64-42), 8-6 | Shibe Park (31-20) | 53-52 | |
| » Starters: Danny MacFayden vs George Earnshaw | Third | 15 out |
| Sunday, August 13 |
| » Lost to Red Sox (47-59), 19-10 | Fenway Park (4-7) | 53-53 | Lost 2 |
| » Starters: Sugar Cain vs Gordon Rhodes | Third | 16 out |
| Monday, August 14 |
| » Defeated Indians (55-58), 11-5 | Cleveland Stadium (5-3) | 54-53 | |
| » Starters: Roy Mahaffey vs Willis Hudlin | Third | 15½ out |
| Tuesday, August 15 |
| » Defeated Indians (55-59), 8-7 | Cleveland Stadium (6-3) | 55-53 | Won 2 |
| » Starters: Lefty Grove vs Wes Ferrell | Third | 15½ out |
| Wednesday, August 16 |
| » Lost to Indians (56-59), 5-4 | Cleveland Stadium (6-4) | 55-54 | |
| » Starters: Sugar Cain vs Oral Hildebrand | Third | 16½ out |
| Thursday, August 17 |
| » Lost to Indians (57-59), 15-4 | Cleveland Stadium (6-5) | 55-55 | Lost 2 |
| » Starters: George Earnshaw vs Monte Pearson | Third | 17½ out |
| Friday, August 18 |
| » Lost to Tigers (56-59), 7-6 | Tiger Stadium (3-4) | 55-56 | Lost 3 |
| » Starters: Roy Mahaffey vs Vic Sorrell | Fourth | 18½ out |
| Saturday, August 19 |
| » Lost to Tigers (57-59), 6-0 | Tiger Stadium (3-5) | 55-57 | Lost 4 |
| » Starters: Rube Walberg vs Firpo Marberry | Fourth | 19½ out |
| Sunday, August 20 |
| » Lost to Tigers (58-59), 5-4 | Tiger Stadium (3-6) | 55-58 | Lost 5 |
| » Starters: Lefty Grove vs Vic Frasier | Fifth | 21½ out |
| » Lost to Tigers (59-59), 4-1 | Tiger Stadium (3-7) | 55-59 | Lost 6 |
| » Starters: Sugar Cain vs Carl Fischer | Fifth | 21½ out |
| Monday, August 21 |
| » Defeated Tigers (59-60), 12-7 | Tiger Stadium (4-7) | 56-59 | |
| » Starters: Dick Barrett vs Elden Auker | Fifth | 21 out |
| Tuesday, August 22 |
| » Defeated Browns (44-77), 7-6 | Sportsman's Park III (5-3) | 57-59 | Won 2 |
| » Starters: Roy Mahaffey vs Jack Knott | Fifth | 20 out |
| Thursday, August 24 |
| » Lost to Browns (45-77), 7-6 | Sportsman's Park III (5-4) | 57-60 | |
| » Starters: Lefty Grove vs Rollie Stiles | Fifth | 20½ out |
| » Defeated Browns (45-78), 4-3 | Sportsman's Park III (6-4) | 58-60 | |
| » Starters: Sugar Cain vs Bump Hadley | Fifth | 20½ out |
| Friday, August 25 |
| » Defeated Browns (45-79), 11-3 | Sportsman's Park III (7-4) | 59-60 | Won 2 |
| » Starters: Dick Barrett vs Ed Wells | Fourth | 20½ out |
| Saturday, August 26 |
| » Defeated White Sox (57-66), 10-5 | Comiskey Park I (3-4) | 60-60 | Won 3 |
| » Starters: Roy Mahaffey vs Ted Lyons | Fourth | 19½ out |
| Sunday, August 27 |
| » Lost to White Sox (58-66), 5-3 | Comiskey Park I (3-5) | 60-61 | |
| » Starters: Rube Walberg vs Joe Heving | Fourth | 20½ out |
| » Lost to White Sox (59-66), 9-8 | Comiskey Park I (3-6) | 60-62 | Lost 2 |
| » Starters: Lefty Grove vs Milt Gaston | Fourth | 20½ out |
| Monday, August 28 |
| » Defeated White Sox (59-67), 9-5 | Comiskey Park I (4-6) | 61-62 | |
| » Starters: Sugar Cain vs Sad Sam Jones | Fourth | 20 out |
| Tuesday, August 29 |
| » Lost to White Sox (60-67), 11-5 | Comiskey Park I (4-7) | 61-63 | |
| » Starters: Dick Barrett vs Jake Miller | Fourth | 20½ out |
| Friday, September 1 |
| » Defeated Senators (82-44), 12-3 | Shibe Park (32-20) | 62-63 | |
| » Starters: Earl Whitehill vs Sugar Cain | Fourth | 19½ out |
| Saturday, September 2 |
| » Defeated Senators (82-45), 7-3 | Shibe Park (33-20) | 63-63 | Won 2 |
| » Starters: Jack Russell vs Lefty Grove | Fourth | 19½ out |
| » Lost to Senators (83-45), 8-4 | Shibe Park (33-21) | 63-64 | |
| » Starters: General Crowder vs Jim Peterson | Fourth | 19½ out |
| Tuesday, September 5 |
| » Defeated Yankees (74-53), 6-1 | Shibe Park (34-21) | 64-64 | |
| » Starters: Lefty Gomez vs Roy Mahaffey | Fourth | 21 out |
| » Lost to Yankees (75-53), 9-6 | Shibe Park (34-22) | 64-65 | |
| » Starters: Charlie Devens vs Sugar Cain | Fourth | 21 out |
| Wednesday, September 6 |
| » Defeated Indians (72-64), 5-4 | Shibe Park (35-22) | 65-65 | |
| » Starters: Mel Harder vs Lefty Grove | Fourth | 21 out |
| Thursday, September 7 |
| » Defeated Indians (72-65), 6-0 | Shibe Park (36-22) | 66-65 | Won 2 |
| » Starters: Monte Pearson vs Johnny Marcum | Fourth | 20 out |
| Friday, September 8 |
| » Defeated Indians (72-66), 9-2 | Shibe Park (37-22) | 67-65 | Won 3 |
| » Starters: Wes Ferrell vs Sugar Cain | Fourth | 20 out |
| Saturday, September 9 |
| » Defeated Indians (72-67), 5-3 | Shibe Park (38-22) | 68-65 | Won 4 |
| » Starters: Clint Brown vs Roy Mahaffey | Fourth | 20 out |
| Monday, September 11 |
| » Defeated White Sox (61-76), 5-3 | Shibe Park (39-22) | 69-65 | Won 5 |
| » Starters: Ted Lyons vs Lefty Grove | Third | 20 out |
| » Defeated White Sox (61-77), 8-0 | Shibe Park (40-22) | 70-65 | Won 6 |
| » Starters: Joe Heving vs Johnny Marcum | Third | 20 out |
| Future Athletic Bob Davis is born in New York, NY. |
| Wednesday, September 13 |
| » Lost to White Sox (62-77), 3-2 | Shibe Park (40-23) | 70-66 | |
| » Starters: Sad Sam Jones vs Jim Peterson | Third | 19½ out |
| » Defeated White Sox (62-78), 4-2 | Shibe Park (41-23) | 71-66 | |
| » Starters: Red Faber vs Sugar Cain | Third | 19½ out |
| Saturday, September 16 |
| » Defeated Browns (52-89), 6-0 | Shibe Park (42-23) | 72-66 | Won 2 |
| » Starters: George Blaeholder vs Lefty Grove | Third | 21 out |
| » Lost to Browns (53-89), 5-2 | Shibe Park (42-24) | 72-67 | |
| » Starters: Bump Hadley vs Johnny Marcum | Third | 21 out |
| Monday, September 18 |
| » Defeated Tigers (69-77), 9-8 | Shibe Park (43-24) | 73-67 | |
| » Starters: Luke Hamlin vs Roy Mahaffey | Third | 20½ out |
| » Major-league debuts: Luke Hamlin (Tigers) |
| Tuesday, September 19 |
| » Defeated Tigers (69-78), 5-2 | Shibe Park (44-24) | 74-67 | Won 2 |
| » Starters: Vic Sorrell vs Sugar Cain | Third | 19½ out |
| Wednesday, September 20 |
| » Defeated Tigers (69-79), 2-1 | Shibe Park (45-24) | 75-67 | Won 3 |
| » Starters: Carl Fischer vs Lefty Grove | Third | 19½ out |
| Thursday, September 21 |
| » Lost to Tigers (70-79), 10-3 | Shibe Park (45-25) | 75-68 | |
| » Starters: Elden Auker vs Johnny Marcum | Third | 20½ out |
| » Major-league debuts: Frankie Hayes (Athletics) |
| Saturday, September 23 |
| » Defeated Senators (97-50), 3-1 | Griffith Stadium (3-6) | 76-68 | |
| » Starters: Sugar Cain vs Monte Weaver | Third | 19½ out |
| Sunday, September 24 |
| » Defeated Senators (97-51), 11-4 | Griffith Stadium (4-6) | 77-68 | Won 2 |
| » Starters: Tim McKeithan vs General Crowder | Third | 18½ out |
| » Major-league debuts: Ray Prim (Senators) |
| Wednesday, September 27 |
| » Lost to Yankees (89-56), 7-0 | Shibe Park (45-26) | 77-69 | |
| » Starters: Lefty Gomez vs Lefty Grove | Third | 18½ out |
| » Defeated Yankees (89-57), 10-1 | Shibe Park (46-26) | 78-69 | |
| » Starters: Johnny Allen vs Johnny Marcum | Third | 18½ out |
| Thursday, September 28 |
| » Lost to Red Sox (61-85), 4-3 | Shibe Park (46-27) | 78-70 | |
| » Starters: Lloyd Brown vs Jim Peterson | Third | 18½ out |
| Saturday, September 30 |
| » Lost to Red Sox (62-85), 2-1 | Shibe Park (46-28) | 78-71 | Lost 2 |
| » Starters: Bob Weiland vs Bill Dietrich | Third | 20½ out |
| » Lost to Red Sox (63-85), 12-1 | Shibe Park (46-29) | 78-72 | Lost 3 |
| » Starters: Ivy Andrews vs Emil Roy | Third | 20½ out |
| Sunday, October 1 |
| » Defeated Senators (99-53), 3-0 | Griffith Stadium (5-6) | 79-72 | |
| » Starters: Rube Walberg vs Ray Prim | Third | 19½ out |
Game information provided by Retrosheet (www.retrosheet.org) |