| Tuesday, February 23 |
| Future Indian Jim Bolger is born in Cincinnati, OH. |
| Friday, March 25 |
| Future Indian Woodie Held is born in Sacramento, CA. |
| Tuesday, April 12 |
| » Major-league debuts: Bill Swift (Pirates) |
| Wednesday, April 13 |
| » Defeated Tigers (0-1), 6-5 | Tiger Stadium (1-0) | 1-0 | |
| » Starters: Wes Ferrell vs Vic Sorrell | Second | ½ out |
| » Major-league debuts: Harry Davis (Tigers) |
| Thursday, April 14 |
| » Lost to Tigers (1-1), 3-1 | Tiger Stadium (1-1) | 1-1 | |
| » Starters: Willis Hudlin vs Whit Wyatt | Fourth | 1 out |
| Friday, April 15 |
| » Lost to Tigers (2-1), 3-2 | Tiger Stadium (1-2) | 1-2 | Lost 2 |
| » Starters: Clint Brown vs Earl Whitehill | Fifth | 2 out |
| » Major-league debuts: Jo-Jo White (Tigers) |
| Saturday, April 16 |
| » Lost to White Sox (4-1), 5-1 | Comiskey Park I (0-1) | 1-3 | Lost 3 |
| » Starters: Mel Harder vs Pat Caraway | Fourth | 2½ out |
| Sunday, April 17 |
| » Defeated White Sox (4-2), 6-1 | Comiskey Park I (1-1) | 2-3 | |
| » Starters: Sarge Connally vs Milt Gaston | Fifth | 1½ out |
| Monday, April 18 |
| » Defeated White Sox (4-3), 2-1 | Comiskey Park I (2-1) | 3-3 | Won 2 |
| » Starters: Wes Ferrell vs Vic Frasier | Fifth | 1 out |
| Tuesday, April 19 |
| » Defeated White Sox (4-4), 4-2 | Comiskey Park I (3-1) | 4-3 | Won 3 |
| » Starters: Willis Hudlin vs Sam Jones | Third | 1 out |
| Wednesday, April 20 |
| » Lost to Tigers (6-2), 2-1 | League Park II (0-1) | 4-4 | |
| » Starters: George Uhle vs Clint Brown | Third | 2 out |
| Thursday, April 21 |
| » Lost to Tigers (7-2), 5-3 | League Park II (0-2) | 4-5 | Lost 2 |
| » Starters: Vic Sorrell vs Mel Harder | Fifth | 3 out |
| Friday, April 22 |
| » Lost to Tigers (8-2), 16-3 | League Park II (0-3) | 4-6 | Lost 3 |
| » Starters: Whit Wyatt vs Sarge Connally | Fifth | 4 out |
| » Major-league debuts: Monte Pearson and Frankie Pytlak (Indians) |
| Saturday, April 23 |
| » Defeated Tigers (8-3), 8-7 | League Park II (1-3) | 5-6 | |
| » Starters: Earl Whitehill vs Wes Ferrell | Fourth | 3 out |
| Sunday, April 24 |
| » Defeated Browns (5-7), 14-3 | Sportsman's Park III (1-0) | 6-6 | Won 2 |
| » Starters: Willis Hudlin vs Wally Hebert | Fourth | 3 out |
| Monday, April 25 |
| » Defeated Browns (5-8), 10-5 | Sportsman's Park III (2-0) | 7-6 | Won 3 |
| » Starters: Clint Brown vs Dolly Gray | Fourth | 2½ out |
| Wednesday, April 27 |
| » Defeated Browns (5-9), 7-1 | Sportsman's Park III (3-0) | 8-6 | Won 4 |
| » Starters: Wes Ferrell vs Lefty Stewart | Fourth | 2 out |
| Thursday, April 28 |
| » Defeated White Sox (5-9), 11-2 | League Park II (2-3) | 9-6 | Won 5 |
| » Starters: Pat Caraway vs Mel Harder | Fourth | 2 out |
| Friday, April 29 |
| » Defeated White Sox (5-10), 7-5 | League Park II (3-3) | 10-6 | Won 6 |
| » Starters: Red Faber vs Willis Hudlin | Fourth | 2 out |
| Saturday, April 30 |
| » Defeated White Sox (5-11), 10-7 | League Park II (4-3) | 11-6 | Won 7 |
| » Starters: Vic Frasier vs Clint Brown | Fourth | 2 out |
| Sunday, May 1 |
| » Defeated White Sox (5-12), 11-1 | League Park II (5-3) | 12-6 | Won 8 |
| » Starters: Milt Gaston vs Wes Ferrell | Third | 1 out |
| Monday, May 2 |
| » Defeated Browns (7-11), 6-5 | League Park II (6-3) | 13-6 | Won 9 |
| » Starters: George Blaeholder vs Mel Harder | Second | 1 out |
| Tuesday, May 3 |
| » Lost to Browns (8-11), 11-8 | League Park II (6-4) | 13-7 | |
| » Starters: Lefty Stewart vs Willis Hudlin | Second | 2 out |
| Wednesday, May 4 |
| » Defeated Browns (8-12), 8-3 | League Park II (7-4) | 14-7 | |
| » Starters: Dolly Gray vs Clint Brown | Second | 1½ out |
| Thursday, May 5 |
| » Lost to Athletics (7-10), 15-3 | Shibe Park (0-1) | 14-8 | |
| » Starters: Wes Ferrell vs Lefty Grove | Third | 2 out |
| Friday, May 6 |
| » Lost to Athletics (8-10), 5-2 | Shibe Park (0-2) | 14-9 | Lost 2 |
| » Starters: Mel Harder vs Roy Mahaffey | Fourth | 2 out |
| Saturday, May 7 |
| » Defeated Athletics (8-11), 10-7 | Shibe Park (1-2) | 15-9 | |
| » Starters: Willis Hudlin vs George Earnshaw | Third | 2 out |
| Sunday, May 8 |
| » Defeated Athletics (8-12), 8-5 | League Park II (8-4) | 16-9 | Won 2 |
| » Starters: Rube Walberg vs Clint Brown | Third | 2 out |
| Monday, May 9 |
| » Lost to Senators (17-5), 3-0 | Griffith Stadium (0-1) | 16-10 | |
| » Starters: Wes Ferrell vs Lloyd Brown | Third | 3 out |
| Thursday, May 12 |
| » Defeated Red Sox (4-18), 5-4 | Fenway Park (1-0) | 17-10 | |
| » Starters: Mel Harder vs Ed Durham | Third | 2½ out |
| Saturday, May 14 |
| » Defeated Red Sox (4-19), 6-0 | Fenway Park (2-0) | 18-10 | Won 2 |
| » Starters: Clint Brown vs Danny MacFayden | Third | 3 out |
| Sunday, May 15 |
| » Lost to Yankees (16-6), 5-0 | Yankee Stadium (0-1) | 18-11 | |
| » Starters: Wes Ferrell vs Red Ruffing | Third | 3 out |
| Monday, May 16 |
| » Lost to Yankees (17-6), 8-0 | Yankee Stadium (0-2) | 18-12 | Lost 2 |
| » Starters: Willis Hudlin vs Lefty Gomez | Third | 3½ out |
| Tuesday, May 17 |
| » Lost to Yankees (18-6), 3-2 | Yankee Stadium (0-3) | 18-13 | Lost 3 |
| » Starters: Mel Harder vs Johnny Allen | Third | 3½ out |
| Wednesday, May 18 |
| » Lost to Yankees (19-6), 3-2 | Yankee Stadium (0-4) | 18-14 | Lost 4 |
| » Starters: Clint Brown vs Hank Johnson | Third | 4½ out |
| Friday, May 20 |
| » Defeated Browns (15-18), 11-7 | League Park II (9-4) | 19-14 | |
| » Starters: Bump Hadley vs Wes Ferrell | Third | 3½ out |
| Saturday, May 21 |
| » Lost to Browns (16-18), 8-7 | League Park II (9-5) | 19-15 | |
| » Starters: Dolly Gray vs Mel Harder | Fourth | 5 out |
| Sunday, May 22 |
| » Lost to Browns (17-18), 4-2 | League Park II (9-6) | 19-16 | Lost 2 |
| » Starters: George Blaeholder vs Clint Brown | Fifth | 5 out |
| Monday, May 23 |
| » Lost to White Sox (12-21), 4-0 | Comiskey Park I (3-2) | 19-17 | Lost 3 |
| » Starters: Oral Hildebrand vs Milt Gaston | Fifth | 6 out |
| Tuesday, May 24 |
| » Lost to White Sox (13-21), 11-7 | Comiskey Park I (3-3) | 19-18 | Lost 4 |
| » Starters: Wes Ferrell vs Vic Frasier | Fifth | 7 out |
| Thursday, May 26 |
| Future Indian Joe Altobelli is born in Detroit, MI. |
| Friday, May 27 |
| » Defeated Browns (18-20), 6-3 | Sportsman's Park III (4-0) | 20-18 | |
| » Starters: Clint Brown vs George Blaeholder | Fifth | 7 out |
| Saturday, May 28 |
| » Defeated Browns (18-21), 3-1 | Sportsman's Park III (5-0) | 21-18 | Won 2 |
| » Starters: Wes Ferrell vs Bump Hadley | Fifth | 5½ out |
| Sunday, May 29 |
| » Lost to Browns (19-21), 12-3 | Sportsman's Park III (5-1) | 21-19 | |
| » Starters: Willis Hudlin vs Dick Coffman | Fifth | 6 out |
| » Defeated Browns (19-22), 2-1 | Sportsman's Park III (6-1) | 22-19 | |
| » Starters: Mel Harder vs Lefty Stewart | Fifth | 6 out |
| Monday, May 30 |
| » Defeated White Sox (14-26), 12-6 | League Park II (10-6) | 23-19 | Won 2 |
| » Starters: Sam Jones vs Sarge Connally | Fifth | 6 out |
| » Defeated White Sox (14-27), 12-11 | League Park II (11-6) | 24-19 | Won 3 |
| » Starters: Paul Gregory vs Oral Hildebrand | Fifth | 6 out |
| Tuesday, May 31 |
| » Lost to White Sox (15-27), 6-5 | League Park II (11-7) | 24-20 | |
| » Starters: Ted Lyons vs Clint Brown | Fifth | 6½ out |
| Friday, June 3 |
| » Defeated Tigers (24-17), 3-1 | Tiger Stadium (2-2) | 25-20 | |
| » Starters: Wes Ferrell vs Tommy Bridges | Fourth | 5½ out |
| » Defeated Tigers (24-18), 10-7 | Tiger Stadium (3-2) | 26-20 | Won 2 |
| » Starters: Mel Harder vs Whit Wyatt | Fourth | 5½ out |
| Saturday, June 4 |
| » Defeated Tigers (24-19), 3-1 | Tiger Stadium (4-2) | 27-20 | Won 3 |
| » Starters: Clint Brown vs Vic Sorrell | Fourth | 5½ out |
| » Lost to Tigers (25-19), 10-4 | Tiger Stadium (4-3) | 27-21 | |
| » Starters: Willis Hudlin vs Earl Whitehill | Fourth | 5½ out |
| Sunday, June 5 |
| » Lost to Tigers (26-19), 10-9 | League Park II (11-8) | 27-22 | Lost 2 |
| » Starters: George Uhle vs Sarge Connally | Fifth | 6½ out |
| Tuesday, June 7 |
| » Defeated Athletics (27-22), 4-3 | League Park II (12-8) | 28-22 | |
| » Starters: Roy Mahaffey vs Wes Ferrell | Fourth | 6½ out |
| Wednesday, June 8 |
| » Lost to Athletics (28-22), 3-1 | League Park II (12-9) | 28-23 | |
| » Starters: Lefty Grove vs Mel Harder | Fifth | 7½ out |
| Thursday, June 9 |
| » Defeated Athletics (28-23), 9-8 | League Park II (13-9) | 29-23 | |
| » Starters: George Earnshaw vs Clint Brown | Fourth | 6½ out |
| Friday, June 10 |
| » Lost to Athletics (29-23), 10-7 | League Park II (13-10) | 29-24 | |
| » Starters: Rube Walberg vs Willis Hudlin | Fifth | 7½ out |
| Saturday, June 11 |
| » Defeated Yankees (35-16), 6-3 | League Park II (14-10) | 30-24 | |
| » Starters: George Pipgras vs Wes Ferrell | Fourth | 6½ out |
| Sunday, June 12 |
| » Lost to Yankees (36-16), 13-5 | League Park II (14-11) | 30-25 | |
| » Starters: Red Ruffing vs Mel Harder | Fifth | 7½ out |
| Monday, June 13 |
| » Lost to Yankees (37-16), 8-7 | League Park II (14-12) | 30-26 | Lost 2 |
| » Starters: Lefty Gomez vs Jack Russell | Fifth | 8½ out |
| Tuesday, June 14 |
| » Lost to Yankees (38-16), 7-6 | League Park II (14-13) | 30-27 | Lost 3 |
| » Starters: Danny MacFayden vs Clint Brown | Fourth | 9½ out |
| Wednesday, June 15 |
| » Defeated Red Sox (11-43), 9-3 | League Park II (15-13) | 31-27 | |
| » Starters: John Michaels vs Wes Ferrell | Fourth | 8½ out |
| Saturday, June 18 |
| » Defeated Red Sox (11-44), 9-2 | League Park II (16-13) | 32-27 | Won 2 |
| » Starters: Ivy Andrews vs Mel Harder | Fourth | 9 out |
| Sunday, June 19 |
| » Defeated Red Sox (11-45), 9-3 | League Park II (17-13) | 33-27 | Won 3 |
| » Starters: Bob Weiland vs Sarge Connally | Third | 8½ out |
| » Defeated Red Sox (11-46), 6-3 | League Park II (18-13) | 34-27 | Won 4 |
| » Starters: Bob Kline vs Clint Brown | Third | 8½ out |
| Monday, June 20 |
| » Lost to Senators (34-27), 3-2 | League Park II (18-14) | 34-28 | |
| » Starters: Alvin Crowder vs Wes Ferrell | Fifth | 9½ out |
| Tuesday, June 21 |
| » Lost to Senators (35-27), 8-3 | League Park II (18-15) | 34-29 | Lost 2 |
| » Starters: Lloyd Brown vs Jack Russell | Fifth | 10½ out |
| Wednesday, June 22 |
| » Defeated Senators (35-28), 11-2 | League Park II (19-15) | 35-29 | |
| » Starters: Dick Coffman vs Mel Harder | Fifth | 9½ out |
| Thursday, June 23 |
| » Lost to Senators (36-28), 6-1 | League Park II (19-16) | 35-30 | |
| » Starters: Tommy Thomas vs Clint Brown | Fifth | 9½ out |
| Sunday, June 26 |
| » Defeated Browns (32-32), 10-5 | League Park II (20-16) | 36-30 | |
| » Starters: George Blaeholder vs Wes Ferrell | Fifth | 10½ out |
| » Lost to Browns (33-32), 6-5 | League Park II (20-17) | 36-31 | |
| » Starters: Carl Fischer vs Mel Harder | Fifth | 10½ out |
| Wednesday, June 29 |
| » Lost to Tigers (38-27), 13-4 | League Park II (20-18) | 36-32 | Lost 2 |
| » Starters: Earl Whitehill vs Clint Brown | Fifth | 12 out |
| Thursday, June 30 |
| » Defeated Tigers (38-28), 7-4 | League Park II (21-18) | 37-32 | |
| » Starters: Vic Sorrell vs Wes Ferrell | Fifth | 12 out |
| Saturday, July 2 |
| » Lost to Tigers (39-28), 5-4 | Tiger Stadium (4-4) | 37-33 | |
| » Starters: Mel Harder vs Izzy Goldstein | Fifth | 12 out |
| Sunday, July 3 |
| » Defeated Tigers (39-29), 7-4 | Tiger Stadium (5-4) | 38-33 | |
| » Starters: Clint Brown vs George Uhle | Fourth | 12 out |
| Monday, July 4 |
| » Defeated White Sox (25-44), 4-2 | Comiskey Park I (4-3) | 39-33 | Won 2 |
| » Starters: Wes Ferrell vs Milt Gaston | Fifth | 11 out |
| » Lost to White Sox (26-44), 2-1 | Comiskey Park I (4-4) | 39-34 | |
| » Starters: Oral Hildebrand vs Ted Lyons | Fifth | 11 out |
| Thursday, July 7 |
| » Defeated Senators (40-35), 3-2 | Griffith Stadium (1-1) | 40-34 | |
| » Starters: Jack Russell vs Tommy Thomas | Fourth | 9½ out |
| » Defeated Senators (40-36), 4-3 | Griffith Stadium (2-1) | 41-34 | Won 2 |
| » Starters: Mel Harder vs Alvin Crowder | Fourth | 9½ out |
| Friday, July 8 |
| » Defeated Senators (40-37), 6-5 | Griffith Stadium (3-1) | 42-34 | Won 3 |
| » Starters: Wes Ferrell vs Dick Coffman | Fourth | 9½ out |
| Saturday, July 9 |
| » Defeated Senators (40-38), 4-1 | Griffith Stadium (4-1) | 43-34 | Won 4 |
| » Starters: Oral Hildebrand vs Lloyd Brown | Fourth | 10½ out |
| » Lost to Senators (41-38), 14-4 | Griffith Stadium (4-2) | 43-35 | |
| » Starters: Sarge Connally vs Monte Weaver | Fourth | 10½ out |
| Sunday, July 10 |
| » Lost to Athletics (48-33), 18-17 | League Park II (21-19) | 43-36 | Lost 2 |
| » Starters: Lew Krausse vs Clint Brown | Fourth | 10 out |
| Monday, July 11 |
| » Defeated Athletics (48-34), 9-8 | Shibe Park (2-2) | 44-36 | |
| » Starters: Jack Russell vs Rube Walberg | Fourth | 9½ out |
| » Defeated Athletics (48-35), 12-7 | Shibe Park (3-2) | 45-36 | Won 2 |
| » Starters: Mel Harder vs Roy Mahaffey | Fourth | 9½ out |
| Tuesday, July 12 |
| » Defeated Athletics (48-36), 7-6 | Shibe Park (4-2) | 46-36 | Won 3 |
| » Starters: Willis Hudlin vs Lefty Grove | Fourth | 9½ out |
| Wednesday, July 13 |
| » Defeated Athletics (48-37), 7-5 | Shibe Park (5-2) | 47-36 | Won 4 |
| » Starters: Oral Hildebrand vs Roy Mahaffey | Second | 9½ out |
| Thursday, July 14 |
| » Defeated Yankees (56-27), 11-3 | Yankee Stadium (1-4) | 48-36 | Won 5 |
| » Starters: Clint Brown vs Herb Pennock | Second | 8½ out |
| Friday, July 15 |
| » Lost to Yankees (57-27), 8-5 | Yankee Stadium (1-5) | 48-37 | |
| » Starters: Wes Ferrell vs Lefty Gomez | Second | 9½ out |
| Saturday, July 16 |
| » Defeated Yankees (57-28), 8-1 | Yankee Stadium (2-5) | 49-37 | |
| » Starters: Mel Harder vs Danny MacFayden | Second | 8½ out |
| Sunday, July 17 |
| » Defeated Red Sox (20-64), 5-4 | Fenway Park (3-0) | 50-37 | Won 2 |
| » Starters: Oral Hildebrand vs John Michaels | Second | 8½ out |
| » Defeated Red Sox (20-65), 8-6 | Fenway Park (4-0) | 51-37 | Won 3 |
| » Starters: Willis Hudlin vs Bob Weiland | Second | 8½ out |
| Monday, July 18 |
| » Lost to Red Sox (21-65), 4-2 | Fenway Park (4-1) | 51-38 | |
| » Starters: Jack Russell vs Ivy Andrews | Third | 9½ out |
| Tuesday, July 19 |
| » Defeated Red Sox (21-66), 7-0 | Fenway Park (5-1) | 52-38 | |
| » Starters: Wes Ferrell vs Bob Weiland | Third | 9½ out |
| Wednesday, July 20 |
| » Defeated Red Sox (21-67), 8-1 | Fenway Park (6-1) | 53-38 | Won 2 |
| » Starters: Mel Harder vs Bob Kline | Third | 9½ out |
| Friday, July 22 |
| » Major-league debuts: Frank Demaree (Cubs) |
| Saturday, July 23 |
| » Lost to White Sox (31-58), 6-5 | Comiskey Park I (4-5) | 53-39 | |
| » Starters: Wes Ferrell vs Ted Lyons | Third | 10½ out |
| Sunday, July 24 |
| » Defeated White Sox (31-59), 9-7 | Comiskey Park I (5-5) | 54-39 | |
| » Starters: Clint Brown vs Sam Jones | Second | 10 out |
| » Defeated White Sox (31-60), 9-6 | Comiskey Park I (6-5) | 55-39 | Won 2 |
| » Starters: Mel Harder vs Milt Gaston | Second | 10 out |
| Tuesday, July 26 |
| Future Indian Dick Brodowski is born in Bayonne, NJ. |
| Wednesday, July 27 |
| » Defeated Yankees (65-31), 2-1 | League Park II (22-19) | 56-39 | Won 3 |
| » Starters: Danny MacFayden vs Oral Hildebrand | Second | 7½ out |
| » Defeated Yankees (65-32), 12-10 | League Park II (23-19) | 57-39 | Won 4 |
| » Starters: Johnny Allen vs Mel Harder | Second | 7½ out |
| Thursday, July 28 |
| » Lost to Yankees (66-32), 10-1 | League Park II (23-20) | 57-40 | |
| » Starters: Red Ruffing vs Wes Ferrell | Second | 8½ out |
| Friday, July 29 |
| » Defeated Yankees (66-33), 4-3 | League Park II (24-20) | 58-40 | |
| » Starters: Lefty Gomez vs Clint Brown | Second | 7½ out |
| Saturday, July 30 |
| » Lost to Athletics (60-42), 7-2 | League Park II (24-21) | 58-41 | |
| » Starters: Roy Mahaffey vs Jack Russell | Third | 8½ out |
| Sunday, July 31 |
| » Lost to Athletics (61-42), 1-0 | Cleveland Stadium (0-1) | 58-42 | Lost 2 |
| » Starters: Lefty Grove vs Mel Harder | Third | 9½ out |
| Monday, August 1 |
| » Lost to Athletics (62-42), 1-0 | Cleveland Stadium (0-2) | 58-43 | Lost 3 |
| » Starters: Rube Walberg vs Wes Ferrell | Third | 10½ out |
| Thursday, August 4 |
| » Defeated Red Sox (26-75), 8-2 | Cleveland Stadium (1-2) | 59-43 | |
| » Starters: Bob Kline vs Oral Hildebrand | Third | 9½ out |
| » Defeated Red Sox (26-76), 8-7 | Cleveland Stadium (2-2) | 60-43 | Won 2 |
| » Starters: Ivy Andrews vs Clint Brown | Third | 9½ out |
| Friday, August 5 |
| » Defeated Red Sox (26-77), 7-2 | Cleveland Stadium (3-2) | 61-43 | Won 3 |
| » Starters: Johnny Welch vs Mel Harder | Third | 9 out |
| Saturday, August 6 |
| » Defeated Red Sox (26-78), 3-0 | Cleveland Stadium (4-2) | 62-43 | Won 4 |
| » Starters: Gordon Rhodes vs Wes Ferrell | Third | 8½ out |
| Sunday, August 7 |
| » Defeated Senators (59-48), 7-4 | Cleveland Stadium (5-2) | 63-43 | Won 5 |
| » Starters: Tommy Thomas vs Jack Russell | Second | 8½ out |
| » Defeated Senators (59-49), 6-2 | Cleveland Stadium (6-2) | 64-43 | Won 6 |
| » Starters: Lloyd Brown vs Willis Hudlin | Second | 8½ out |
| Monday, August 8 |
| » Lost to Senators (60-49), 7-6 | Cleveland Stadium (6-3) | 64-44 | |
| » Starters: Monte Weaver vs Oral Hildebrand | Third | 9 out |
| Tuesday, August 9 |
| » Lost to Senators (61-49), 4-2 | Cleveland Stadium (6-4) | 64-45 | Lost 2 |
| » Starters: Alvin Crowder vs Mel Harder | Third | 10 out |
| Thursday, August 11 |
| » Defeated Tigers (57-50), 3-0 | Cleveland Stadium (7-4) | 65-45 | |
| » Starters: Earl Whitehill vs Wes Ferrell | Third | 10 out |
| Friday, August 12 |
| » Defeated Tigers (57-51), 3-1 | Cleveland Stadium (8-4) | 66-45 | Won 2 |
| » Starters: Vic Sorrell vs Clint Brown | Second | 9½ out |
| Saturday, August 13 |
| » Defeated Tigers (57-52), 8-3 | Cleveland Stadium (9-4) | 67-45 | Won 3 |
| » Starters: Chief Hogsett vs Willis Hudlin | Third | 9½ out |
| Sunday, August 14 |
| » Lost to Tigers (58-52), 3-0 | Cleveland Stadium (9-5) | 67-46 | |
| » Starters: Tommy Bridges vs Oral Hildebrand | Third | 10½ out |
| Tuesday, August 16 |
| » Defeated Athletics (69-47), 3-2 | Shibe Park (6-2) | 68-46 | |
| » Starters: Mel Harder vs George Earnshaw | Second | 11 out |
| Wednesday, August 17 |
| » Lost to Athletics (70-47), 11-0 | Shibe Park (6-3) | 68-47 | |
| » Starters: Wes Ferrell vs Lefty Grove | Third | 12 out |
| » Major-league debuts: Boze Berger (Indians) |
| Thursday, August 18 |
| Former Indian Candy LaChance dies in Waterville, CT at the age of 63. |
| Friday, August 19 |
| » Lost to Athletics (71-47), 9-7 | Shibe Park (6-4) | 68-48 | Lost 2 |
| » Starters: Willis Hudlin vs Rube Walberg | Third | 13 out |
| » Lost to Athletics (72-47), 3-2 | Shibe Park (6-5) | 68-49 | Lost 3 |
| » Starters: Clint Brown vs Tony Freitas | Third | 13 out |
| Saturday, August 20 |
| » Lost to Senators (66-51), 4-2 | Griffith Stadium (4-3) | 68-50 | Lost 4 |
| » Starters: Jack Russell vs Alvin Crowder | Third | 13½ out |
| » Defeated Senators (66-52), 11-5 | Griffith Stadium (5-3) | 69-50 | |
| » Starters: Oral Hildebrand vs Monte Weaver | Third | 13½ out |
| Sunday, August 21 |
| » Defeated Senators (66-53), 11-5 | Griffith Stadium (6-3) | 70-50 | Won 2 |
| » Starters: Wes Ferrell vs Lloyd Brown | Third | 13½ out |
| Monday, August 22 |
| » Lost to Senators (67-53), 4-0 | Griffith Stadium (6-4) | 70-51 | |
| » Starters: Willis Hudlin vs Firpo Marberry | Third | 13½ out |
| Tuesday, August 23 |
| » Lost to Senators (68-53), 5-4 | Griffith Stadium (6-5) | 70-52 | Lost 2 |
| » Starters: Mel Harder vs Alvin Crowder | Third | 14½ out |
| Wednesday, August 24 |
| » Lost to Yankees (85-37), 9-3 | Yankee Stadium (2-6) | 70-53 | Lost 3 |
| » Starters: Clint Brown vs Red Ruffing | Third | 15½ out |
| Future Indian Hal Woodeshick is born in Wilkes-Barre, PA. |
| Thursday, August 25 |
| » Lost to Yankees (86-37), 4-3 | Yankee Stadium (2-7) | 70-54 | Lost 4 |
| » Starters: Oral Hildebrand vs Lefty Gomez | Fourth | 16½ out |
| Friday, August 26 |
| » Lost to Yankees (87-37), 4-2 | Yankee Stadium (2-8) | 70-55 | Lost 5 |
| » Starters: Wes Ferrell vs Johnny Allen | Fourth | 17½ out |
| Saturday, August 27 |
| » Lost to Yankees (88-37), 5-4 | Yankee Stadium (2-9) | 70-56 | Lost 6 |
| » Starters: Mel Harder vs Herb Pennock | Fourth | 18½ out |
| Future Indian Jim King is born in Elkins, AR. |
| Sunday, August 28 |
| » Defeated Red Sox (35-91), 10-1 | Fenway Park (7-1) | 71-56 | |
| » Starters: Willis Hudlin vs Bob Weiland | Fourth | 18½ out |
| » Lost to Red Sox (36-91), 4-3 | Fenway Park (7-2) | 71-57 | |
| » Starters: Clint Brown vs Ivy Andrews | Fourth | 18½ out |
| Monday, August 29 |
| » Defeated Red Sox (36-92), 6-3 | Fenway Park (8-2) | 72-57 | |
| » Starters: Oral Hildebrand vs Gordon Rhodes | Fourth | 19 out |
| Tuesday, August 30 |
| » Lost to Red Sox (37-92), 6-2 | Fenway Park (8-3) | 72-58 | |
| » Starters: Wes Ferrell vs Johnny Welch | Fourth | 20 out |
| Sunday, September 4 |
| » Defeated Tigers (65-65), 11-3 | Tiger Stadium (6-4) | 73-58 | |
| » Starters: Clint Brown vs Vic Sorrell | Fourth | 19½ out |
| Monday, September 5 |
| » Defeated Browns (57-74), 12-9 | Sportsman's Park III (7-1) | 74-58 | Won 2 |
| » Starters: Mel Harder vs Lefty Stewart | Fourth | 19½ out |
| » Defeated Browns (57-75), 6-4 | Sportsman's Park III (8-1) | 75-58 | Won 3 |
| » Starters: Willis Hudlin vs George Blaeholder | Fourth | 19½ out |
| Tuesday, September 6 |
| » Defeated Browns (57-76), 4-3 | Sportsman's Park III (9-1) | 76-58 | Won 4 |
| » Starters: Jack Russell vs Bump Hadley | Fourth | 18½ out |
| » Defeated Browns (57-77), 6-0 | Sportsman's Park III (10-1) | 77-58 | Won 5 |
| » Starters: Sarge Connally vs Dolly Gray | Fourth | 18½ out |
| Wednesday, September 7 |
| » Major-league debuts: Dick Siebert (Dodgers) |
| Thursday, September 8 |
| » Defeated Athletics (84-55), 2-1 | Cleveland Stadium (10-5) | 78-58 | Won 6 |
| » Starters: Lefty Grove vs Clint Brown | Fourth | 18½ out |
| Saturday, September 10 |
| » Lost to Athletics (85-55), 4-3 | Cleveland Stadium (10-6) | 78-59 | |
| » Starters: George Earnshaw vs Mel Harder | Fourth | 19 out |
| Sunday, September 11 |
| » Defeated Yankees (99-43), 5-4 | Cleveland Stadium (11-6) | 79-59 | |
| » Starters: Johnny Allen vs Wes Ferrell | Fourth | 18 out |
| Monday, September 12 |
| » Lost to Yankees (100-43), 8-3 | Cleveland Stadium (11-7) | 79-60 | |
| » Starters: Red Ruffing vs Oral Hildebrand | Fourth | 19 out |
| Tuesday, September 13 |
| » Lost to Yankees (101-43), 9-3 | Cleveland Stadium (11-8) | 79-61 | Lost 2 |
| » Starters: George Pipgras vs Clint Brown | Fourth | 20 out |
| Wednesday, September 14 |
| » Defeated Red Sox (40-102), 9-0 | Cleveland Stadium (12-8) | 80-61 | |
| » Starters: Gordon Rhodes vs Mel Harder | Fourth | 20 out |
| Thursday, September 15 |
| » Defeated Red Sox (40-103), 7-2 | Cleveland Stadium (13-8) | 81-61 | Won 2 |
| » Starters: Ed Durham vs Willis Hudlin | Fourth | 19 out |
| Friday, September 16 |
| » Lost to Red Sox (41-103), 6-2 | Cleveland Stadium (13-9) | 81-62 | |
| » Starters: Ivy Andrews vs Clint Brown | Fourth | 20 out |
| Saturday, September 17 |
| » Defeated Senators (86-59), 5-4 | Cleveland Stadium (14-9) | 82-62 | |
| » Starters: Dick Coffman vs Wes Ferrell | Fourth | 20 out |
| Sunday, September 18 |
| » Defeated Senators (86-60), 7-3 | Cleveland Stadium (15-9) | 83-62 | Won 2 |
| » Starters: Firpo Marberry vs Jack Russell | Fourth | 20 out |
| » Lost to Senators (87-60), 9-2 | Cleveland Stadium (15-10) | 83-63 | |
| » Starters: Alvin Crowder vs Oral Hildebrand | Fourth | 20 out |
| Tuesday, September 20 |
| » Defeated Browns (61-86), 5-2 | Cleveland Stadium (16-10) | 84-63 | |
| » Starters: Carl Fischer vs Clint Brown | Fourth | 19 out |
| » Defeated Browns (61-87), 11-2 | Cleveland Stadium (17-10) | 85-63 | Won 2 |
| » Starters: Bump Hadley vs Willis Hudlin | Fourth | 19 out |
| Wednesday, September 21 |
| » Lost to Browns (62-87), 4-3 | Cleveland Stadium (17-11) | 85-64 | |
| » Starters: Lefty Stewart vs Mel Harder | Fourth | 19 out |
| Friday, September 23 |
| » Defeated White Sox (48-101), 13-6 | Cleveland Stadium (18-11) | 86-64 | |
| » Starters: Ed Walsh vs Wes Ferrell | Fourth | 19½ out |
| Saturday, September 24 |
| » Lost to White Sox (49-101), 8-7 | Cleveland Stadium (18-12) | 86-65 | |
| » Starters: Charlie Biggs vs Jack Russell | Fourth | 20½ out |
| Sunday, September 25 |
| » Defeated White Sox (49-102), 6-4 | Cleveland Stadium (19-12) | 87-65 | |
| » Starters: Paul Gregory vs Ralph Winegarner | Fourth | 19½ out |
| » Tied White Sox, 5-5 | Cleveland Stadium (19-12) | 87-65 | |
| » Starters: Ed Walsh vs Willis Hudlin | Fourth | 19½ out |
| Friday, October 7 |
| Future Indian Buddy Daley is born in Orange, CA. |
| Wednesday, November 2 |
| Former Indian Frank Cross dies in Geauga Lake, OH at the age of 60. |
| Friday, November 25 |
| Former Indian Charlie Carr dies in Memphis, TN at the age of 56. |
Game information provided by Retrosheet (www.retrosheet.org) |
