| Wednesday, January 7 |
| Future Tiger Ray Semproch is born in Cleveland, OH. |
| Saturday, January 31 |
| Future Tiger Hank Aguirre is born in Azusa, CA. |
| Sunday, February 1 |
| Future Tiger Bob Smith is born in Woodsville, NH. |
| Tuesday, April 14 |
| » Lost to Browns (1-0), 7-3 | Sportsman's Park III (0-1) | 0-1 | |
| » Starters: Earl Whitehill vs Lefty Stewart | Second | 1 out |
| » Major-league debuts: Gee Walker (Tigers) |
| Wednesday, April 15 |
| » Lost to Browns (2-0), 6-4 | Sportsman's Park III (0-2) | 0-2 | Lost 2 |
| » Starters: Waite Hoyt vs Dolly Gray | Third | 2 out |
| » Major-league debuts: Hub Walker (Tigers) |
| Thursday, April 16 |
| » Defeated Browns (2-1), 6-5 | Sportsman's Park III (1-2) | 1-2 | |
| » Starters: Vic Sorrell vs George Blaeholder | Third | 2 out |
| » Major-league debuts: Marv Owen (Tigers) |
| Saturday, April 18 |
| » Lost to Browns (3-1), 7-3 | Sportsman's Park III (1-3) | 1-3 | |
| » Starters: Tommy Bridges vs Lefty Stewart | Second | 2 out |
| Sunday, April 19 |
| » Defeated Indians (3-2), 7-2 | League Park II (1-0) | 2-3 | |
| » Starters: Earl Whitehill vs Wes Ferrell | Third | 2 out |
| Monday, April 20 |
| » Lost to Indians (4-2), 9-3 | League Park II (1-1) | 2-4 | |
| » Starters: Waite Hoyt vs Willis Hudlin | Fourth | 2 out |
| Tuesday, April 21 |
| » Lost to Indians (5-2), 5-4 | League Park II (1-2) | 2-5 | Lost 2 |
| » Starters: Vic Sorrell vs Clint Brown | Fourth | 3 out |
| Wednesday, April 22 |
| » Major-league debuts: Gene Rye (Red Sox) |
| Thursday, April 23 |
| » Defeated Browns (3-3), 1-0 | Tiger Stadium (1-0) | 3-5 | |
| » Starters: Lefty Stewart vs Tommy Bridges | Sixth | 3 out |
| Friday, April 24 |
| » Defeated Browns (3-4), 4-2 | Tiger Stadium (2-0) | 4-5 | Won 2 |
| » Starters: Dolly Gray vs Earl Whitehill | Fourth | 3 out |
| Saturday, April 25 |
| » Defeated Browns (3-5), 3-1 | Tiger Stadium (3-0) | 5-5 | Won 3 |
| » Starters: Dick Coffman vs Waite Hoyt | Second | 2 out |
| Sunday, April 26 |
| » Defeated White Sox (3-6), 8-4 | Comiskey Park I (1-0) | 6-5 | Won 4 |
| » Starters: Vic Sorrell vs Vic Frasier | Third | 1½ out |
| Tuesday, April 28 |
| » Lost to White Sox (4-6), 6-5 | Comiskey Park I (1-1) | 6-6 | |
| » Starters: Vic Sorrell vs Pat Caraway | Fourth | 2½ out |
| Wednesday, April 29 |
| » Lost to White Sox (5-6), 3-0 | Comiskey Park I (1-2) | 6-7 | Lost 2 |
| » Starters: Earl Whitehill vs Tommy Thomas | Fifth | 3½ out |
| Thursday, April 30 |
| » Defeated Indians (9-4), 9-4 | Tiger Stadium (4-0) | 7-7 | |
| » Starters: Willis Hudlin vs Waite Hoyt | Fifth | 2½ out |
| Friday, May 1 |
| » Defeated Indians (9-5), 4-2 | Tiger Stadium (5-0) | 8-7 | Won 2 |
| » Starters: Mel Harder vs Charlie Sullivan | Fourth | 1½ out |
| Saturday, May 2 |
| » Lost to Indians (10-5), 3-1 | Tiger Stadium (5-1) | 8-8 | |
| » Starters: Clint Brown vs Vic Sorrell | Sixth | 2½ out |
| Sunday, May 3 |
| » Lost to Indians (11-5), 7-4 | Tiger Stadium (5-2) | 8-9 | Lost 2 |
| » Starters: Wes Ferrell vs Earl Whitehill | Sixth | 3½ out |
| Monday, May 4 |
| » Defeated White Sox (8-8), 9-3 | Tiger Stadium (6-2) | 9-9 | |
| » Starters: Hal McKain vs Waite Hoyt | Sixth | 2½ out |
| Tuesday, May 5 |
| » Lost to White Sox (9-8), 7-3 | Tiger Stadium (6-3) | 9-10 | |
| » Starters: Vic Frasier vs Charlie Sullivan | Sixth | 3½ out |
| Wednesday, May 6 |
| » Defeated White Sox (9-9), 9-4 | Tiger Stadium (7-3) | 10-10 | |
| » Starters: Pat Caraway vs Tommy Bridges | Fifth | 3 out |
| Thursday, May 7 |
| » Defeated White Sox (9-10), 6-1 | Tiger Stadium (8-3) | 11-10 | Won 2 |
| » Starters: Tommy Thomas vs Vic Sorrell | Fourth | 2 out |
| Friday, May 8 |
| » Defeated Senators (10-11), 3-2 | Tiger Stadium (9-3) | 12-10 | Won 3 |
| » Starters: Lloyd Brown vs Earl Whitehill | Fourth | 1 out |
| Sunday, May 10 |
| » Lost to Senators (11-11), 7-4 | Tiger Stadium (9-4) | 12-11 | |
| » Starters: Sam Jones vs Waite Hoyt | Fourth | 1½ out |
| Monday, May 11 |
| » Lost to Senators (12-11), 14-4 | Tiger Stadium (9-5) | 12-12 | Lost 2 |
| » Starters: Carl Fischer vs Tommy Bridges | Fifth | 2 out |
| Tuesday, May 12 |
| » Defeated Red Sox (9-12), 2-0 | Tiger Stadium (10-5) | 13-12 | |
| » Starters: Jack Russell vs Vic Sorrell | Fifth | 3½ out |
| Wednesday, May 13 |
| » Defeated Red Sox (9-13), 2-1 | Tiger Stadium (11-5) | 14-12 | Won 2 |
| » Starters: Milt Gaston vs Earl Whitehill | Fourth | 3½ out |
| Thursday, May 14 |
| » Lost to Red Sox (10-13), 4-3 | Tiger Stadium (11-6) | 14-13 | |
| » Starters: Ed Durham vs Waite Hoyt | Fourth | 3½ out |
| Friday, May 15 |
| » Defeated Yankees (14-9), 2-0 | Tiger Stadium (12-6) | 15-13 | |
| » Starters: Herb Pennock vs George Uhle | Fourth | 3½ out |
| Saturday, May 16 |
| » Defeated Yankees (14-10), 3-1 | Tiger Stadium (13-6) | 16-13 | Won 2 |
| » Starters: Hank Johnson vs Tommy Bridges | Fourth | 3½ out |
| Sunday, May 17 |
| » Lost to Yankees (15-10), 8-5 | Tiger Stadium (13-7) | 16-14 | |
| » Starters: Roy Sherid vs Vic Sorrell | Fourth | 3½ out |
| Monday, May 18 |
| » Lost to Yankees (16-10), 20-8 | Tiger Stadium (13-8) | 16-15 | Lost 2 |
| » Starters: Ed Wells vs Earl Whitehill | Fourth | 4½ out |
| Tuesday, May 19 |
| » Lost to Athletics (18-7), 5-0 | Tiger Stadium (13-9) | 16-16 | Lost 3 |
| » Starters: George Earnshaw vs Waite Hoyt | Fourth | 5½ out |
| Wednesday, May 20 |
| » Lost to Athletics (19-7), 3-0 | Tiger Stadium (13-10) | 16-17 | Lost 4 |
| » Starters: Lefty Grove vs George Uhle | Fourth | 6½ out |
| Thursday, May 21 |
| » Lost to Athletics (20-7), 12-5 | Tiger Stadium (13-11) | 16-18 | Lost 5 |
| » Starters: Eddie Rommel vs Tommy Bridges | Fourth | 7½ out |
| Saturday, May 23 |
| » Lost to Browns (10-17), 7-2 | Sportsman's Park III (1-4) | 16-19 | Lost 6 |
| » Starters: Waite Hoyt vs Dolly Gray | Fourth | 9 out |
| » Lost to Browns (11-17), 6-5 | Sportsman's Park III (1-5) | 16-20 | Lost 7 |
| » Starters: Earl Whitehill vs George Blaeholder | Fourth | 9 out |
| Sunday, May 24 |
| » Lost to Browns (12-17), 10-3 | Sportsman's Park III (1-6) | 16-21 | Lost 8 |
| » Starters: Vic Sorrell vs Lefty Stewart | Fourth | 9½ out |
| » Defeated Browns (12-18), 3-1 | Sportsman's Park III (2-6) | 17-21 | |
| » Starters: Tommy Bridges vs Dick Coffman | Fourth | 9½ out |
| Tuesday, May 26 |
| » Defeated White Sox (14-20), 4-2 | Comiskey Park I (2-2) | 18-21 | Won 2 |
| » Starters: George Uhle vs Red Faber | Fourth | 9½ out |
| Wednesday, May 27 |
| » Lost to White Sox (15-20), 5-4 | Comiskey Park I (2-3) | 18-22 | |
| » Starters: Earl Whitehill vs Vic Frasier | Sixth | 11 out |
| » Lost to White Sox (16-20), 10-1 | Comiskey Park I (2-4) | 18-23 | Lost 2 |
| » Starters: Waite Hoyt vs Pat Caraway | Sixth | 11 out |
| Thursday, May 28 |
| » Lost to White Sox (17-20), 3-2 | Comiskey Park I (2-5) | 18-24 | Lost 3 |
| » Starters: Vic Sorrell vs Ted Lyons | Sixth | 12 out |
| Friday, May 29 |
| » Lost to Indians (19-20), 9-2 | Tiger Stadium (13-12) | 18-25 | Lost 4 |
| » Starters: Clint Brown vs Tommy Bridges | Sixth | 12½ out |
| Sunday, May 31 |
| » Lost to Indians (20-20), 6-4 | Tiger Stadium (13-13) | 18-26 | Lost 5 |
| » Starters: Willis Hudlin vs George Uhle | Sixth | 13 out |
| Tuesday, June 2 |
| » Lost to Senators (25-16), 5-3 | Griffith Stadium (0-1) | 18-27 | Lost 6 |
| » Starters: Earl Whitehill vs Carl Fischer | Sixth | 14 out |
| Wednesday, June 3 |
| » Lost to Senators (26-16), 2-1 | Griffith Stadium (0-2) | 18-28 | Lost 7 |
| » Starters: Vic Sorrell vs Bobby Burke | Sixth | 15 out |
| Thursday, June 4 |
| » Lost to Senators (27-16), 5-1 | Griffith Stadium (0-3) | 18-29 | Lost 8 |
| » Starters: Tommy Bridges vs Alvin Crowder | Seventh | 16 out |
| Friday, June 5 |
| » Defeated Senators (27-17), 1-0 | Griffith Stadium (1-3) | 19-29 | |
| » Starters: George Uhle vs Sam Jones | Sixth | 15 out |
| Saturday, June 6 |
| » Lost to Athletics (32-11), 11-5 | Shibe Park (0-1) | 19-30 | |
| » Starters: Waite Hoyt vs Rube Walberg | Sixth | 16 out |
| Sunday, June 7 |
| » Lost to Athletics (33-11), 12-2 | Tiger Stadium (13-14) | 19-31 | Lost 2 |
| » Starters: Roy Mahaffey vs Vic Sorrell | Sixth | 17 out |
| Monday, June 8 |
| » Lost to Athletics (34-11), 7-3 | Shibe Park (0-2) | 19-32 | Lost 3 |
| » Starters: Earl Whitehill vs Lefty Grove | Seventh | 18 out |
| Tuesday, June 9 |
| » Lost to Athletics (35-11), 12-3 | Shibe Park (0-3) | 19-33 | Lost 4 |
| » Starters: Tommy Bridges vs George Earnshaw | Eighth | 19 out |
| Thursday, June 11 |
| » Major-league debuts: Lew Krausse (Athletics) |
| Friday, June 12 |
| » Lost to Red Sox (18-29), 3-1 | Fenway Park (0-1) | 19-34 | Lost 5 |
| » Starters: George Uhle vs Jack Russell | Seventh | 19½ out |
| Saturday, June 13 |
| » Lost to Red Sox (19-29), 7-1 | Fenway Park (0-2) | 19-35 | Lost 6 |
| » Starters: Whit Wyatt vs Ed Morris | Eighth | 21 out |
| Sunday, June 14 |
| » Defeated Yankees (27-21), 4-2 | Yankee Stadium (1-0) | 20-35 | |
| » Starters: Vic Sorrell vs Lefty Gomez | Sixth | 20 out |
| Monday, June 15 |
| » Defeated Yankees (27-22), 8-5 | Yankee Stadium (2-0) | 21-35 | Won 2 |
| » Starters: Earl Whitehill vs Red Ruffing | Seventh | 20 out |
| Friday, June 19 |
| » Defeated Red Sox (20-31), 7-6 | Tiger Stadium (14-14) | 22-35 | Won 3 |
| » Starters: Jack Russell vs George Uhle | Sixth | 20½ out |
| Saturday, June 20 |
| » Defeated Red Sox (20-32), 5-4 | Tiger Stadium (15-14) | 23-35 | Won 4 |
| » Starters: Ed Morris vs Vic Sorrell | Fifth | 20½ out |
| Sunday, June 21 |
| » Lost to Red Sox (21-32), 7-6 | Tiger Stadium (15-15) | 23-36 | |
| » Starters: Bob Kline vs Earl Whitehill | Sixth | 21½ out |
| Monday, June 22 |
| » Lost to Red Sox (22-32), 7-2 | Tiger Stadium (15-16) | 23-37 | Lost 2 |
| » Starters: Danny MacFayden vs Tommy Bridges | Sixth | 21½ out |
| Tuesday, June 23 |
| » Lost to Senators (42-19), 10-3 | Tiger Stadium (15-17) | 23-38 | Lost 3 |
| » Starters: Bobby Burke vs Waite Hoyt | Sixth | 22½ out |
| » Lost to Senators (43-19), 4-0 | Tiger Stadium (15-18) | 23-39 | Lost 4 |
| » Starters: Firpo Marberry vs George Uhle | Sixth | 22½ out |
| Wednesday, June 24 |
| » Defeated Senators (43-20), 7-5 | Tiger Stadium (16-18) | 24-39 | |
| » Starters: Lloyd Brown vs Earl Whitehill | Sixth | 21½ out |
| Thursday, June 25 |
| » Lost to Senators (44-20), 4-3 | Tiger Stadium (16-19) | 24-40 | |
| » Starters: Carl Fischer vs Vic Sorrell | Seventh | 21 out |
| Saturday, June 27 |
| » Lost to Athletics (45-18), 9-5 | Tiger Stadium (16-20) | 24-41 | Lost 2 |
| » Starters: Lefty Grove vs Art Herring | Seventh | 22 out |
| Sunday, June 28 |
| » Lost to Athletics (46-18), 9-1 | Tiger Stadium (16-21) | 24-42 | Lost 3 |
| » Starters: Roy Mahaffey vs Tommy Bridges | Seventh | 24 out |
| » Lost to Athletics (47-18), 5-1 | Tiger Stadium (16-22) | 24-43 | Lost 4 |
| » Starters: Rube Walberg vs George Uhle | Seventh | 24 out |
| Monday, June 29 |
| » Defeated Athletics (47-19), 6-5 | Tiger Stadium (17-22) | 25-43 | |
| » Starters: Eddie Rommel vs Earl Whitehill | Seventh | 23 out |
| Tuesday, June 30 |
| » Defeated Yankees (35-30), 8-7 | Tiger Stadium (18-22) | 26-43 | Won 2 |
| » Starters: George Pipgras vs Vic Sorrell | Seventh | 23 out |
| Wednesday, July 1 |
| » Lost to Yankees (36-30), 4-2 | Tiger Stadium (18-23) | 26-44 | |
| » Starters: Herb Pennock vs Art Herring | Seventh | 24 out |
| Thursday, July 2 |
| » Lost to Yankees (37-30), 13-1 | Tiger Stadium (18-24) | 26-45 | Lost 2 |
| » Starters: Ed Wells vs George Uhle | Seventh | 24 out |
| Saturday, July 4 |
| » Lost to Indians (36-35), 6-3 | League Park II (1-3) | 26-46 | Lost 3 |
| » Starters: Earl Whitehill vs Clint Brown | Seventh | 25 out |
| » Defeated Indians (36-36), 8-5 | League Park II (2-3) | 27-46 | |
| » Starters: Tommy Bridges vs Mel Harder | Seventh | 25 out |
| Sunday, July 5 |
| » Defeated Indians (36-37), 5-4 | Tiger Stadium (19-24) | 28-46 | Won 2 |
| » Starters: Wes Ferrell vs Vic Sorrell | Seventh | 24 out |
| Monday, July 6 |
| » Lost to Indians (37-37), 13-4 | League Park II (2-4) | 28-47 | |
| » Starters: Chief Hogsett vs Willis Hudlin | Seventh | 24½ out |
| Wednesday, July 8 |
| » Lost to Browns (34-41), 7-1 | Tiger Stadium (19-25) | 28-48 | Lost 2 |
| » Starters: George Blaeholder vs Tommy Bridges | Seventh | 26 out |
| Thursday, July 9 |
| » Defeated Browns (34-42), 11-7 | Tiger Stadium (20-25) | 29-48 | |
| » Starters: Dolly Gray vs Earl Whitehill | Seventh | 25 out |
| Saturday, July 11 |
| » Lost to Browns (35-42), 6-1 | Tiger Stadium (20-26) | 29-49 | |
| » Starters: Lefty Stewart vs George Uhle | Sixth | 25 out |
| » Defeated Browns (35-43), 5-4 | Tiger Stadium (21-26) | 30-49 | |
| » Starters: Wally Hebert vs Vic Sorrell | Sixth | 25 out |
| Sunday, July 12 |
| » Defeated Browns (35-44), 7-2 | Tiger Stadium (22-26) | 31-49 | Won 2 |
| » Starters: George Blaeholder vs Chief Hogsett | Sixth | 25½ out |
| Tuesday, July 14 |
| » Defeated Athletics (57-25), 12-3 | Shibe Park (1-3) | 32-49 | Won 3 |
| » Starters: Art Herring vs George Earnshaw | Sixth | 24½ out |
| Wednesday, July 15 |
| » Lost to Athletics (58-25), 5-3 | Shibe Park (1-4) | 32-50 | |
| » Starters: Tommy Bridges vs Waite Hoyt | Sixth | 26½ out |
| » Lost to Athletics (59-25), 11-0 | Shibe Park (1-5) | 32-51 | Lost 2 |
| » Starters: Earl Whitehill vs Hank McDonald | Sixth | 26½ out |
| Thursday, July 16 |
| » Lost to Athletics (60-25), 5-3 | Shibe Park (1-6) | 32-52 | Lost 3 |
| » Starters: Vic Sorrell vs Roy Mahaffey | Sixth | 27½ out |
| Friday, July 17 |
| » Lost to Athletics (61-25), 6-3 | Shibe Park (1-7) | 32-53 | Lost 4 |
| » Starters: George Uhle vs Lefty Grove | Sixth | 28½ out |
| Saturday, July 18 |
| » Lost to Senators (55-32), 5-2 | Griffith Stadium (1-4) | 32-54 | Lost 5 |
| » Starters: Earl Whitehill vs Sam Jones | Sixth | 30 out |
| Sunday, July 19 |
| » Lost to Senators (56-32), 2-1 | Griffith Stadium (1-5) | 32-55 | Lost 6 |
| » Starters: Art Herring vs Lloyd Brown | Seventh | 30½ out |
| Monday, July 20 |
| » Lost to Senators (57-32), 7-3 | Griffith Stadium (1-6) | 32-56 | Lost 7 |
| » Starters: Chief Hogsett vs Firpo Marberry | Seventh | 31½ out |
| Tuesday, July 21 |
| » Defeated Senators (57-33), 4-3 | Griffith Stadium (2-6) | 33-56 | |
| » Starters: Vic Sorrell vs Carl Fischer | Seventh | 31½ out |
| Wednesday, July 22 |
| » Defeated Yankees (49-36), 3-2 | Yankee Stadium (3-0) | 34-56 | Won 2 |
| » Starters: George Uhle vs Gordon Rhodes | Seventh | 32 out |
| » Lost to Yankees (50-36), 9-5 | Yankee Stadium (3-1) | 34-57 | |
| » Starters: Tommy Bridges vs Red Ruffing | Seventh | 32 out |
| Thursday, July 23 |
| » Lost to Yankees (51-36), 7-6 | Yankee Stadium (3-2) | 34-58 | Lost 2 |
| » Starters: Earl Whitehill vs Herb Pennock | Seventh | 33 out |
| Friday, July 24 |
| » Lost to Yankees (52-36), 6-5 | Yankee Stadium (3-3) | 34-59 | Lost 3 |
| » Starters: Chief Hogsett vs Lefty Gomez | Seventh | 34 out |
| Saturday, July 25 |
| » Lost to Yankees (53-36), 10-7 | Yankee Stadium (3-4) | 34-60 | Lost 4 |
| » Starters: Vic Sorrell vs Jim Weaver | Eighth | 35½ out |
| Sunday, July 26 |
| » Lost to Red Sox (35-56), 7-6 | Braves Field (0-1) | 34-61 | Lost 5 |
| » Starters: Art Herring vs Danny MacFayden | Eighth | 35 out |
| » Defeated Red Sox (35-57), 7-3 | Braves Field (1-1) | 35-61 | |
| » Starters: Charlie Sullivan vs Jack Russell | Eighth | 35 out |
| Monday, July 27 |
| » Lost to Red Sox (36-57), 13-4 | Fenway Park (0-3) | 35-62 | |
| » Starters: Tommy Bridges vs Danny MacFayden | Eighth | 36 out |
| Tuesday, July 28 |
| » Lost to Red Sox (37-57), 8-1 | Fenway Park (0-4) | 35-63 | Lost 2 |
| » Starters: Earl Whitehill vs Hod Lisenbee | Eighth | 37 out |
| Wednesday, July 29 |
| » Lost to Red Sox (38-57), 5-4 | Fenway Park (0-5) | 35-64 | Lost 3 |
| » Starters: George Uhle vs Jack Russell | Eighth | 37½ out |
| » Defeated Red Sox (38-58), 8-6 | Fenway Park (1-5) | 36-64 | |
| » Starters: Chief Hogsett vs Bob Kline | Eighth | 37½ out |
| Saturday, August 1 |
| » Lost to White Sox (37-60), 6-0 | Tiger Stadium (22-27) | 36-65 | |
| » Starters: Vic Frasier vs Vic Sorrell | Eighth | 38 out |
| » Major-league debuts: George Quellich (Tigers) |
| Sunday, August 2 |
| » Defeated White Sox (37-61), 8-4 | Tiger Stadium (23-27) | 37-65 | |
| » Starters: Tommy Thomas vs Art Herring | Eighth | 37 out |
| Monday, August 3 |
| » Defeated White Sox (37-62), 7-2 | Tiger Stadium (24-27) | 38-65 | Won 2 |
| » Starters: Red Faber vs Earl Whitehill | Eighth | 37½ out |
| Tuesday, August 4 |
| » Lost to White Sox (38-62), 5-1 | Tiger Stadium (24-28) | 38-66 | |
| » Starters: Vic Frasier vs Chief Hogsett | Eighth | 38 out |
| Wednesday, August 5 |
| » Defeated Indians (49-54), 11-8 | Tiger Stadium (25-28) | 39-66 | |
| » Starters: Clint Brown vs Vic Sorrell | Eighth | 37½ out |
| Thursday, August 6 |
| » Lost to Indians (50-54), 4-3 | Tiger Stadium (25-29) | 39-67 | |
| » Starters: Willis Hudlin vs Art Herring | Eighth | 37½ out |
| Saturday, August 8 |
| » Defeated Indians (50-55), 7-1 | League Park II (3-4) | 40-67 | |
| » Starters: Earl Whitehill vs Wes Ferrell | Eighth | 36½ out |
| Sunday, August 9 |
| » Defeated Indians (50-56), 9-8 | League Park II (4-4) | 41-67 | Won 2 |
| » Starters: Chief Hogsett vs Sarge Connally | Eighth | 36½ out |
| Tuesday, August 11 |
| » Lost to Athletics (78-30), 8-1 | Tiger Stadium (25-30) | 41-68 | |
| » Starters: Lefty Grove vs Vic Sorrell | Seventh | 37½ out |
| Wednesday, August 12 |
| » Defeated Athletics (78-31), 7-6 | Tiger Stadium (26-30) | 42-68 | |
| » Starters: George Earnshaw vs Art Herring | Seventh | 36½ out |
| Thursday, August 13 |
| » Lost to Athletics (79-31), 5-2 | Tiger Stadium (26-31) | 42-69 | |
| » Starters: Rube Walberg vs Earl Whitehill | Eighth | 37½ out |
| Saturday, August 15 |
| » Lost to Yankees (64-46), 7-5 | Tiger Stadium (26-32) | 42-70 | Lost 2 |
| » Starters: Ivy Andrews vs Chief Hogsett | Eighth | 38½ out |
| » Major-league debuts: Ivy Andrews (Yankees) |
| Sunday, August 16 |
| » Lost to Yankees (65-46), 9-6 | Tiger Stadium (26-33) | 42-71 | Lost 3 |
| » Starters: Herb Pennock vs Art Herring | Eighth | 39½ out |
| Monday, August 17 |
| » Defeated Yankees (65-47), 8-2 | Tiger Stadium (27-33) | 43-71 | |
| » Starters: Ed Wells vs Vic Sorrell | Seventh | 39 out |
| Tuesday, August 18 |
| » Defeated Yankees (65-48), 5-4 | Tiger Stadium (28-33) | 44-71 | Won 2 |
| » Starters: Red Ruffing vs Earl Whitehill | Seventh | 38½ out |
| Wednesday, August 19 |
| » Lost to Red Sox (47-68), 9-8 | Tiger Stadium (28-34) | 44-72 | |
| » Starters: Danny MacFayden vs Charlie Sullivan | Eighth | 39½ out |
| Thursday, August 20 |
| » Defeated Red Sox (47-69), 7-2 | Tiger Stadium (29-34) | 45-72 | |
| » Starters: Hod Lisenbee vs Art Herring | Seventh | 38½ out |
| Friday, August 21 |
| » Defeated Red Sox (47-70), 11-5 | Tiger Stadium (30-34) | 46-72 | Won 2 |
| » Starters: Ed Durham vs George Uhle | Seventh | 38½ out |
| Saturday, August 22 |
| » Defeated Red Sox (47-71), 9-6 | Tiger Stadium (31-34) | 47-72 | Won 3 |
| » Starters: Jack Russell vs Vic Sorrell | Seventh | 38½ out |
| Sunday, August 23 |
| » Lost to Senators (72-47), 6-5 | Tiger Stadium (31-35) | 47-73 | |
| » Starters: Bobby Burke vs Earl Whitehill | Seventh | 39 out |
| Monday, August 24 |
| » Defeated Senators (72-48), 6-5 | Tiger Stadium (32-35) | 48-73 | |
| » Starters: Firpo Marberry vs Chief Hogsett | Sixth | 39 out |
| Tuesday, August 25 |
| » Lost to Senators (73-48), 5-1 | Tiger Stadium (32-36) | 48-74 | |
| » Starters: Lloyd Brown vs Art Herring | Sixth | 40 out |
| Wednesday, August 26 |
| » Defeated Senators (73-49), 5-4 | Tiger Stadium (33-36) | 49-74 | |
| » Starters: Sam Jones vs Earl Whitehill | Sixth | 39 out |
| Thursday, August 27 |
| » Defeated White Sox (48-76), 9-4 | Tiger Stadium (34-36) | 50-74 | Won 2 |
| » Starters: Pat Caraway vs Vic Sorrell | Sixth | 38½ out |
| Saturday, August 29 |
| » Lost to White Sox (49-76), 10-4 | Tiger Stadium (34-37) | 50-75 | |
| » Starters: Vic Frasier vs Tommy Bridges | Seventh | 40 out |
| Sunday, August 30 |
| » Lost to White Sox (50-76), 10-8 | Tiger Stadium (34-38) | 50-76 | Lost 2 |
| » Starters: Tommy Thomas vs George Uhle | Seventh | 40 out |
| Monday, August 31 |
| » Defeated Browns (53-75), 8-3 | Sportsman's Park III (3-6) | 51-76 | |
| » Starters: Earl Whitehill vs Rollie Stiles | Sixth | 40 out |
| Wednesday, September 2 |
| » Defeated Browns (53-76), 7-3 | Sportsman's Park III (4-6) | 52-76 | Won 2 |
| » Starters: Vic Sorrell vs Dolly Gray | Sixth | 39 out |
| » Lost to Browns (54-76), 5-4 | Sportsman's Park III (4-7) | 52-77 | |
| » Starters: Chief Hogsett vs George Blaeholder | Sixth | 39 out |
| Thursday, September 3 |
| » Defeated White Sox (51-78), 9-3 | Comiskey Park I (3-5) | 53-77 | |
| » Starters: Art Herring vs Bob Weiland | Sixth | 38½ out |
| Friday, September 4 |
| » Defeated White Sox (51-79), 4-3 | Comiskey Park I (4-5) | 54-77 | Won 2 |
| » Starters: Earl Whitehill vs Ted Lyons | Sixth | 39 out |
| Saturday, September 5 |
| » Defeated White Sox (51-80), 8-3 | Comiskey Park I (5-5) | 55-77 | Won 3 |
| » Starters: Tommy Bridges vs Pat Caraway | Fifth | 38½ out |
| Sunday, September 6 |
| » Lost to White Sox (52-80), 4-1 | Comiskey Park I (5-6) | 55-78 | |
| » Starters: Vic Sorrell vs Vic Frasier | Fifth | 39½ out |
| Monday, September 7 |
| » Defeated Browns (55-80), 3-2 | Tiger Stadium (35-38) | 56-78 | |
| » Starters: Dick Coffman vs George Uhle | Fifth | 38½ out |
| » Lost to Browns (56-80), 11-7 | Tiger Stadium (35-39) | 56-79 | |
| » Starters: George Blaeholder vs Chief Hogsett | Fifth | 38½ out |
| Tuesday, September 8 |
| » Lost to Browns (57-80), 3-2 | Tiger Stadium (35-40) | 56-80 | Lost 2 |
| » Starters: Lefty Stewart vs Earl Whitehill | Sixth | 39½ out |
| Thursday, September 10 |
| » Defeated Red Sox (50-85), 3-0 | Fenway Park (2-5) | 57-80 | |
| » Starters: Tommy Bridges vs Wilcy Moore | Fifth | 39 out |
| Friday, September 11 |
| » Lost to Red Sox (51-85), 5-0 | Fenway Park (2-6) | 57-81 | |
| » Starters: Orlin Collier vs Danny MacFayden | Fifth | 39½ out |
| Saturday, September 12 |
| » Lost to Red Sox (52-85), 1-0 | Fenway Park (2-7) | 57-82 | Lost 2 |
| » Starters: Art Herring vs Ed Durham | Sixth | 40 out |
| Former Tiger Frank Dillon dies in Pasadena, CA at the age of 58. |
| Sunday, September 13 |
| » Lost to Yankees (81-57), 2-1 | Yankee Stadium (3-5) | 57-83 | Lost 3 |
| » Starters: George Uhle vs Lefty Gomez | Sixth | 41 out |
| » Lost to Yankees (82-57), 4-3 | Yankee Stadium (3-6) | 57-84 | Lost 4 |
| » Starters: Earl Whitehill vs Herb Pennock | Sixth | 41 out |
| Future Tiger George Susce is born in Pittsburgh, PA. |
| Monday, September 14 |
| » Lost to Yankees (83-57), 2-1 | Yankee Stadium (3-7) | 57-85 | Lost 5 |
| » Starters: Vic Sorrell vs George Pipgras | Sixth | 41½ out |
| Tuesday, September 15 |
| » Lost to Yankees (84-57), 9-2 | Yankee Stadium (3-8) | 57-86 | Lost 6 |
| » Starters: Tommy Bridges vs Gordon Rhodes | Sixth | 42½ out |
| Thursday, September 17 |
| » Defeated Senators (86-57), 3-1 | Griffith Stadium (3-6) | 58-86 | |
| » Starters: Art Herring vs Carl Fischer | Fifth | 42½ out |
| » Major-league debuts: Babe Phelps (Senators) |
| Friday, September 18 |
| » Lost to Senators (87-57), 4-3 | Griffith Stadium (3-7) | 58-87 | |
| » Starters: Earl Whitehill vs Firpo Marberry | Fifth | 43½ out |
| Saturday, September 19 |
| » Defeated Senators (87-58), 3-2 | Griffith Stadium (4-7) | 59-87 | |
| » Starters: Vic Sorrell vs Lloyd Brown | Fifth | 44 out |
| Monday, September 21 |
| » Lost to Athletics (104-43), 3-2 | Shibe Park (1-8) | 59-88 | |
| » Starters: Chief Hogsett vs Eddie Rommel | Fifth | 44 out |
| » Defeated Athletics (104-44), 6-5 | Shibe Park (2-8) | 60-88 | |
| » Starters: Tommy Bridges vs Jim Peterson | Fifth | 44 out |
| Tuesday, September 22 |
| » Lost to Athletics (105-44), 8-6 | Shibe Park (2-9) | 60-89 | |
| » Starters: Art Herring vs George Earnshaw | Sixth | 45 out |
| Wednesday, September 23 |
| » Defeated Indians (74-76), 9-7 | Tiger Stadium (36-40) | 61-89 | |
| » Starters: Willis Hudlin vs Orlin Collier | Sixth | 45 out |
| » Lost to Indians (75-76), 6-2 | Tiger Stadium (36-41) | 61-90 | |
| » Starters: Clint Brown vs Vic Sorrell | Sixth | 45 out |
| Thursday, September 24 |
| » Lost to Indians (76-76), 6-4 | League Park II (4-5) | 61-91 | Lost 2 |
| » Starters: Earl Whitehill vs Oral Hildebrand | Sixth | 46 out |
| Saturday, September 26 |
| » Lost to Indians (77-76), 7-3 | League Park II (4-6) | 61-92 | Lost 3 |
| » Starters: Tommy Bridges vs Wes Ferrell | Seventh | 47 out |
| Sunday, September 27 |
| » Lost to Indians (78-76), 8-5 | League Park II (4-7) | 61-93 | Lost 4 |
| » Starters: Art Herring vs Pete Appleton | Seventh | 47 out |
| Tuesday, October 13 |
| Future Tiger Eddie Mathews is born in Texarkana, TX. |
| Thursday, October 15 |
| Future Tiger Gail Harris is born in Abingdon, VA. |
| Friday, October 16 |
| Future Tiger Dave Sisler is born in St. Louis, MO. |
| Friday, October 23 |
| Future Tiger Jim Bunning is born in Southgate, KY. |
| Monday, November 9 |
| Future Tiger Whitey Herzog is born in New Athens, IL. |
| Monday, November 16 |
| Future Tiger Frank Bolling is born in Mobile, AL. |
| Thursday, December 10 |
| Former Tiger Tex Covington dies in Denison, TX at the age of 45. |
| Sunday, December 13 |
| Future Tiger Bubba Morton is born in Washington, DC. |
| Wednesday, December 16 |
| Future Tiger Neil Chrisley is born in Calhoun Falls, SC. |
Game information provided by Retrosheet (www.retrosheet.org) |
