| Wednesday, January 7 |
| Future Senator Bunky Stewart is born in Jasper, NC. |
| Saturday, January 17 |
| Future Senator Don Zimmer is born in Cincinnati, OH. |
| Friday, March 13 |
| Future Senator Carlos Pascual is born in Havana, Cuba. |
| Tuesday, April 14 |
| » Lost to Athletics (1-0), 5-3 | Griffith Stadium (0-1) | 0-1 | |
| » Starters: Rube Walberg vs Lloyd Brown | Second | 1 out |
| Wednesday, April 15 |
| » Defeated Athletics (1-1), 7-1 | Griffith Stadium (1-1) | 1-1 | |
| » Starters: George Earnshaw vs Bump Hadley | Second | 1 out |
| Thursday, April 16 |
| » Defeated Athletics (1-2), 5-4 | Griffith Stadium (2-1) | 2-1 | Won 2 |
| » Starters: Hank McDonald vs Alvin Crowder | Second | 1 out |
| Saturday, April 18 |
| » Defeated Athletics (1-3), 2-1 | Griffith Stadium (3-1) | 3-1 | Won 3 |
| » Starters: Lefty Grove vs Sam Jones | First | -- |
| Sunday, April 19 |
| » Defeated Red Sox (1-4), 8-0 | Griffith Stadium (4-1) | 4-1 | Won 4 |
| » Starters: Danny MacFayden vs Lloyd Brown | First | -- |
| Monday, April 20 |
| » Lost to Red Sox (2-4), 13-3 | Griffith Stadium (4-2) | 4-2 | |
| » Starters: Jack Russell vs Alvin Crowder | First | -- |
| » Major-league debuts: Cliff Bolton (Senators) |
| Tuesday, April 21 |
| » Defeated Red Sox (2-5), 12-3 | Griffith Stadium (5-2) | 5-2 | |
| » Starters: Milt Gaston vs Firpo Marberry | First | -- |
| Wednesday, April 22 |
| » Lost to Athletics (3-5), 5-1 | Shibe Park (0-1) | 5-3 | |
| » Starters: Bump Hadley vs Lefty Grove | Second | 1 out |
| Thursday, April 23 |
| Former Senator Bill Otey dies in Dayton, OH at the age of 45. |
| Friday, April 24 |
| » Lost to Athletics (4-5), 10-7 | Shibe Park (0-2) | 5-4 | Lost 2 |
| » Starters: Sam Jones vs Hank McDonald | Third | 2 out |
| Saturday, April 25 |
| » Lost to Athletics (5-5), 3-2 | Shibe Park (0-3) | 5-5 | Lost 3 |
| » Starters: Lloyd Brown vs Rube Walberg | Second | 2 out |
| Sunday, April 26 |
| » Defeated Yankees (7-4), 9-7 | Griffith Stadium (6-2) | 6-5 | |
| » Starters: Hank Johnson vs Firpo Marberry | Third | 1½ out |
| Monday, April 27 |
| » Defeated Yankees (7-5), 9-8 | Griffith Stadium (7-2) | 7-5 | Won 2 |
| » Starters: Herb Pennock vs Bump Hadley | Second | 1 out |
| Tuesday, April 28 |
| » Tied Yankees, 7-7 | Griffith Stadium (7-2) | 7-5 | |
| » Starters: Roy Sherid vs Sam Jones | Second | 1½ out |
| » Major-league debuts: Dixie Walker (Yankees) |
| Wednesday, April 29 |
| » Defeated Yankees (7-6), 9-5 | Griffith Stadium (8-2) | 8-5 | Won 3 |
| » Starters: Ed Wells vs Lloyd Brown | Second | 1½ out |
| Friday, May 1 |
| » Lost to Red Sox (4-7), 10-4 | Fenway Park (0-1) | 8-6 | |
| » Starters: Alvin Crowder vs Jack Russell | Second | 1 out |
| Saturday, May 2 |
| » Defeated Red Sox (4-8), 6-2 | Fenway Park (1-1) | 9-6 | |
| » Starters: Carl Fischer vs Danny MacFayden | Third | 1½ out |
| » Lost to Red Sox (5-8), 3-2 | Fenway Park (1-2) | 9-7 | |
| » Starters: Firpo Marberry vs Ed Morris | Third | 1½ out |
| Sunday, May 3 |
| » Lost to Athletics (7-6), 3-1 | Griffith Stadium (8-3) | 9-8 | Lost 2 |
| » Starters: Rube Walberg vs Lloyd Brown | Fifth | 2½ out |
| Monday, May 4 |
| » Defeated Yankees (9-8), 7-3 | Yankee Stadium (1-0) | 10-8 | |
| » Starters: Sam Jones vs Lefty Gomez | Second | 1½ out |
| Tuesday, May 5 |
| » Lost to Yankees (10-8), 18-8 | Yankee Stadium (1-1) | 10-9 | |
| » Starters: Bump Hadley vs Herb Pennock | Fifth | 2½ out |
| Wednesday, May 6 |
| » Lost to Yankees (11-8), 10-7 | Yankee Stadium (1-2) | 10-10 | Lost 2 |
| » Starters: Carl Fischer vs Hank Johnson | Fifth | 3 out |
| Friday, May 8 |
| » Lost to Tigers (12-10), 3-2 | Tiger Stadium (0-1) | 10-11 | Lost 3 |
| » Starters: Lloyd Brown vs Earl Whitehill | Fifth | 2½ out |
| Sunday, May 10 |
| » Defeated Tigers (12-11), 7-4 | Tiger Stadium (1-1) | 11-11 | |
| » Starters: Sam Jones vs Waite Hoyt | Fifth | 2 out |
| Monday, May 11 |
| » Defeated Tigers (12-12), 14-4 | Tiger Stadium (2-1) | 12-11 | Won 2 |
| » Starters: Carl Fischer vs Tommy Bridges | Fourth | 1½ out |
| Wednesday, May 13 |
| » Defeated Indians (12-11), 9-3 | League Park II (1-0) | 13-11 | Won 3 |
| » Starters: Lloyd Brown vs Wes Ferrell | Third | 2½ out |
| Thursday, May 14 |
| » Defeated Indians (12-12), 5-4 | League Park II (2-0) | 14-11 | Won 4 |
| » Starters: Sam Jones vs Jake Miller | Third | 2½ out |
| Friday, May 15 |
| » Defeated Browns (6-15), 8-5 | Sportsman's Park III (1-0) | 15-11 | Won 5 |
| » Starters: Firpo Marberry vs Lefty Stewart | Third | 2½ out |
| Saturday, May 16 |
| » Defeated Browns (6-16), 9-7 | Sportsman's Park III (2-0) | 16-11 | Won 6 |
| » Starters: Carl Fischer vs Rip Collins | Second | 2½ out |
| Sunday, May 17 |
| » Lost to Browns (7-16), 7-1 | Sportsman's Park III (2-1) | 16-12 | |
| » Starters: Alvin Crowder vs Dolly Gray | Third | 3 out |
| » Defeated Browns (7-17), 4-2 | Sportsman's Park III (3-1) | 17-12 | |
| » Starters: Lloyd Brown vs George Blaeholder | Third | 3 out |
| Wednesday, May 20 |
| » Defeated White Sox (12-16), 2-0 | Comiskey Park I (1-0) | 18-12 | Won 2 |
| » Starters: Sam Jones vs Pat Caraway | Third | 3 out |
| Thursday, May 21 |
| » Defeated White Sox (12-17), 4-2 | Comiskey Park I (2-0) | 19-12 | Won 3 |
| » Starters: Bump Hadley vs Tommy Thomas | Third | 3 out |
| Saturday, May 23 |
| » Lost to Yankees (19-10), 7-6 | Yankee Stadium (1-3) | 19-13 | |
| » Starters: Lloyd Brown vs Herb Pennock | Third | 4 out |
| Sunday, May 24 |
| » Defeated Red Sox (11-20), 10-9 | Griffith Stadium (9-3) | 20-13 | |
| » Starters: Danny MacFayden vs Alvin Crowder | Third | 4 out |
| Tuesday, May 26 |
| » Lost to Red Sox (12-20), 6-4 | Fenway Park (1-3) | 20-14 | |
| » Starters: Sam Jones vs Jack Russell | Third | 5 out |
| Wednesday, May 27 |
| » Defeated Red Sox (12-21), 11-3 | Fenway Park (2-3) | 21-14 | |
| » Starters: Lloyd Brown vs Hod Lisenbee | Second | 4½ out |
| » Defeated Red Sox (12-22), 4-3 | Fenway Park (3-3) | 22-14 | Won 2 |
| » Starters: Carl Fischer vs Ed Morris | Second | 4½ out |
| Thursday, May 28 |
| » Defeated Red Sox (12-23), 4-3 | Fenway Park (4-3) | 23-14 | Won 3 |
| » Starters: Alvin Crowder vs Danny MacFayden | Second | 4½ out |
| Saturday, May 30 |
| » Defeated Yankees (20-16), 3-2 | Griffith Stadium (10-3) | 24-14 | Won 4 |
| » Starters: Herb Pennock vs Sam Jones | Second | 4½ out |
| » Lost to Yankees (21-16), 9-8 | Griffith Stadium (10-4) | 24-15 | |
| » Starters: Hank Johnson vs Bobby Burke | Second | 4½ out |
| Sunday, May 31 |
| » Lost to Yankees (22-16), 4-2 | Griffith Stadium (10-5) | 24-16 | Lost 2 |
| » Starters: Ed Wells vs Lloyd Brown | Second | 5 out |
| Tuesday, June 2 |
| » Defeated Tigers (18-27), 5-3 | Griffith Stadium (11-5) | 25-16 | |
| » Starters: Earl Whitehill vs Carl Fischer | Second | 5 out |
| Future Senator Marshall Bridges is born in Jackson, MS. |
| Wednesday, June 3 |
| » Defeated Tigers (18-28), 2-1 | Griffith Stadium (12-5) | 26-16 | Won 2 |
| » Starters: Vic Sorrell vs Bobby Burke | Second | 5 out |
| Thursday, June 4 |
| » Defeated Tigers (18-29), 5-1 | Griffith Stadium (13-5) | 27-16 | Won 3 |
| » Starters: Tommy Bridges vs Alvin Crowder | Second | 5 out |
| Friday, June 5 |
| » Lost to Tigers (19-29), 1-0 | Griffith Stadium (13-6) | 27-17 | |
| » Starters: George Uhle vs Sam Jones | Second | 5 out |
| Saturday, June 6 |
| » Defeated White Sox (18-25), 7-3 | Griffith Stadium (14-6) | 28-17 | |
| » Starters: Pat Caraway vs Carl Fischer | Second | 5 out |
| Sunday, June 7 |
| » Defeated White Sox (18-26), 8-1 | Griffith Stadium (15-6) | 29-17 | Won 2 |
| » Starters: Ted Lyons vs Lloyd Brown | Second | 5 out |
| Monday, June 8 |
| » Defeated White Sox (18-27), 18-4 | Griffith Stadium (16-6) | 30-17 | Won 3 |
| » Starters: Tommy Thomas vs Bobby Burke | Second | 5 out |
| Tuesday, June 9 |
| » Defeated White Sox (18-28), 9-3 | Griffith Stadium (17-6) | 31-17 | Won 4 |
| » Starters: Pat Caraway vs Alvin Crowder | Second | 5 out |
| » Major-league debuts: Billy Sullivan (White Sox) |
| Wednesday, June 10 |
| » Defeated Indians (25-23), 9-4 | Griffith Stadium (18-6) | 32-17 | Won 5 |
| » Starters: Willis Hudlin vs Sam Jones | Second | 4½ out |
| Thursday, June 11 |
| » Defeated Indians (25-24), 12-5 | Griffith Stadium (19-6) | 33-17 | Won 6 |
| » Starters: Clint Brown vs Lloyd Brown | Second | 3½ out |
| Friday, June 12 |
| » Defeated Indians (25-25), 7-1 | Griffith Stadium (20-6) | 34-17 | Won 7 |
| » Starters: Wes Ferrell vs Carl Fischer | Second | 3½ out |
| Saturday, June 13 |
| » Defeated Indians (25-26), 5-0 | Griffith Stadium (21-6) | 35-17 | Won 8 |
| » Starters: Milt Shoffner vs Alvin Crowder | Second | 4 out |
| Sunday, June 14 |
| » Defeated Browns (17-30), 9-3 | Griffith Stadium (22-6) | 36-17 | Won 9 |
| » Starters: George Blaeholder vs Bobby Burke | Second | 3 out |
| Monday, June 15 |
| » Defeated Browns (17-31), 4-3 | Griffith Stadium (23-6) | 37-17 | Won 10 |
| » Starters: Dolly Gray vs Lloyd Brown | Second | 3 out |
| Tuesday, June 16 |
| » Defeated Browns (17-32), 11-10 | Griffith Stadium (24-6) | 38-17 | Won 11 |
| » Starters: Wally Hebert vs Carl Fischer | Second | 2½ out |
| Wednesday, June 17 |
| » Defeated Browns (17-33), 8-7 | Griffith Stadium (25-6) | 39-17 | Won 12 |
| » Starters: Lefty Stewart vs Alvin Crowder | Second | 2½ out |
| Friday, June 19 |
| » Lost to Indians (27-28), 9-6 | League Park II (2-1) | 39-18 | |
| » Starters: Sam Jones vs Jake Miller | Second | 3½ out |
| Saturday, June 20 |
| » Defeated Indians (27-29), 14-4 | League Park II (3-1) | 40-18 | |
| » Starters: Lloyd Brown vs Milt Shoffner | Second | 3 out |
| » Defeated Indians (27-30), 7-3 | League Park II (4-1) | 41-18 | Won 2 |
| » Starters: Carl Fischer vs Roxie Lawson | Second | 3 out |
| Sunday, June 21 |
| » Lost to Indians (28-30), 3-1 | League Park II (4-2) | 41-19 | |
| » Starters: Alvin Crowder vs Wes Ferrell | Second | 4 out |
| Monday, June 22 |
| Future Senator Faye Throneberry is born in Fisherville, TN. |
| Tuesday, June 23 |
| » Defeated Tigers (23-38), 10-3 | Tiger Stadium (3-1) | 42-19 | |
| » Starters: Bobby Burke vs Waite Hoyt | Second | 2½ out |
| » Defeated Tigers (23-39), 4-0 | Tiger Stadium (4-1) | 43-19 | Won 2 |
| » Starters: Firpo Marberry vs George Uhle | Second | 2½ out |
| Wednesday, June 24 |
| » Lost to Tigers (24-39), 7-5 | Tiger Stadium (4-2) | 43-20 | |
| » Starters: Lloyd Brown vs Earl Whitehill | Second | 2½ out |
| Thursday, June 25 |
| » Defeated Tigers (24-40), 4-3 | Tiger Stadium (5-2) | 44-20 | |
| » Starters: Carl Fischer vs Vic Sorrell | Second | 1 out |
| Friday, June 26 |
| » Lost to White Sox (21-39), 4-3 | Comiskey Park I (2-1) | 44-21 | |
| » Starters: Alvin Crowder vs Pat Caraway | Second | 1½ out |
| Saturday, June 27 |
| » Defeated White Sox (21-40), 8-2 | Comiskey Park I (3-1) | 45-21 | |
| » Starters: Firpo Marberry vs Jim Moore | Second | 1½ out |
| Sunday, June 28 |
| » Lost to White Sox (22-40), 2-1 | Comiskey Park I (3-2) | 45-22 | |
| » Starters: Bobby Burke vs Tommy Thomas | Second | 2½ out |
| » Defeated White Sox (22-41), 3-1 | Comiskey Park I (4-2) | 46-22 | |
| » Starters: Lloyd Brown vs Hal McKain | Second | 2½ out |
| Monday, June 29 |
| » Lost to White Sox (23-41), 9-7 | Comiskey Park I (4-3) | 46-23 | |
| » Starters: Sam Jones vs Vic Frasier | Second | 2½ out |
| Tuesday, June 30 |
| » Lost to Browns (29-37), 7-0 | Sportsman's Park III (3-2) | 46-24 | Lost 2 |
| » Starters: Carl Fischer vs George Blaeholder | Second | 3½ out |
| Future Senator Yo-Yo Davalillo is born in Caracas, Venezuela. |
| Wednesday, July 1 |
| » Lost to Browns (30-37), 4-3 | Sportsman's Park III (3-3) | 46-25 | Lost 3 |
| » Starters: Firpo Marberry vs Dolly Gray | Second | 4½ out |
| Thursday, July 2 |
| » Defeated Browns (30-38), 13-5 | Sportsman's Park III (4-3) | 47-25 | |
| » Starters: Bobby Burke vs Lefty Stewart | Second | 3½ out |
| Friday, July 3 |
| Future Senator Ed Roebuck is born in East Millsboro, PA. |
| Saturday, July 4 |
| » Lost to Yankees (38-30), 6-1 | Yankee Stadium (1-4) | 47-26 | |
| » Starters: Lloyd Brown vs Lefty Gomez | Second | 5½ out |
| » Lost to Yankees (39-30), 7-4 | Yankee Stadium (1-5) | 47-27 | Lost 2 |
| » Starters: Carl Fischer vs Hank Johnson | Second | 5½ out |
| Sunday, July 5 |
| » Defeated Athletics (51-21), 4-2 | Griffith Stadium (26-6) | 48-27 | |
| » Starters: George Earnshaw vs Firpo Marberry | Second | 4½ out |
| Monday, July 6 |
| » Tied Athletics, 0-0 | Griffith Stadium (26-6) | 48-27 | |
| » Starters: Rube Walberg vs Bump Hadley | Second | 4½ out |
| Tuesday, July 7 |
| » Lost to Athletics (52-21), 7-3 | Griffith Stadium (26-7) | 48-28 | |
| » Starters: George Earnshaw vs Alvin Crowder | Second | 5½ out |
| Wednesday, July 8 |
| » Lost to Athletics (53-21), 6-3 | Griffith Stadium (26-8) | 48-29 | Lost 2 |
| » Starters: Lefty Grove vs Lloyd Brown | Second | 6½ out |
| Thursday, July 9 |
| » Defeated Red Sox (28-44), 14-1 | Griffith Stadium (27-8) | 49-29 | |
| » Starters: Wilcy Moore vs Firpo Marberry | Second | 5½ out |
| Saturday, July 11 |
| » Defeated Red Sox (28-45), 7-1 | Griffith Stadium (28-8) | 50-29 | Won 2 |
| » Starters: Danny MacFayden vs Lloyd Brown | Second | 4½ out |
| » Defeated Red Sox (28-46), 8-7 | Griffith Stadium (29-8) | 51-29 | Won 3 |
| » Starters: Jack Russell vs Carl Fischer | Second | 4½ out |
| Sunday, July 12 |
| » Lost to Yankees (44-32), 10-4 | Griffith Stadium (29-9) | 51-30 | |
| » Starters: Herb Pennock vs Bump Hadley | Second | 6 out |
| Monday, July 13 |
| » Lost to Athletics (57-23), 12-7 | Shibe Park (0-4) | 51-31 | Lost 2 |
| » Starters: Firpo Marberry vs Lefty Grove | Second | 6 out |
| » Defeated Athletics (57-24), 6-4 | Shibe Park (1-4) | 52-31 | |
| » Starters: Alvin Crowder vs Rube Walberg | Second | 6 out |
| Tuesday, July 14 |
| » Lost to White Sox (30-49), 9-1 | Griffith Stadium (29-10) | 52-32 | |
| » Starters: Red Faber vs Carl Fischer | Second | 6 out |
| Thursday, July 16 |
| » Defeated White Sox (30-50), 5-4 | Griffith Stadium (30-10) | 53-32 | |
| » Starters: Tommy Thomas vs Firpo Marberry | Second | 7 out |
| Friday, July 17 |
| » Defeated White Sox (30-51), 12-7 | Griffith Stadium (31-10) | 54-32 | Won 2 |
| » Starters: Vic Frasier vs Alvin Crowder | Second | 7 out |
| Saturday, July 18 |
| » Defeated Tigers (32-54), 5-2 | Griffith Stadium (32-10) | 55-32 | Won 3 |
| » Starters: Earl Whitehill vs Sam Jones | Second | 7½ out |
| Sunday, July 19 |
| » Defeated Tigers (32-55), 2-1 | Griffith Stadium (33-10) | 56-32 | Won 4 |
| » Starters: Art Herring vs Lloyd Brown | Second | 7 out |
| Monday, July 20 |
| » Defeated Tigers (32-56), 7-3 | Griffith Stadium (34-10) | 57-32 | Won 5 |
| » Starters: Chief Hogsett vs Firpo Marberry | Second | 7 out |
| Tuesday, July 21 |
| » Lost to Tigers (33-56), 4-3 | Griffith Stadium (34-11) | 57-33 | |
| » Starters: Vic Sorrell vs Carl Fischer | Second | 8 out |
| Wednesday, July 22 |
| » Lost to Browns (40-48), 8-4 | Griffith Stadium (34-12) | 57-34 | Lost 2 |
| » Starters: Dolly Gray vs Alvin Crowder | Second | 9 out |
| Thursday, July 23 |
| » Lost to Browns (41-48), 6-4 | Griffith Stadium (34-13) | 57-35 | Lost 3 |
| » Starters: Wally Hebert vs Sam Jones | Second | 10 out |
| Saturday, July 25 |
| » Defeated Browns (41-49), 7-1 | Griffith Stadium (35-13) | 58-35 | |
| » Starters: Lefty Stewart vs Firpo Marberry | Second | 11 out |
| Sunday, July 26 |
| » Lost to Browns (42-49), 5-2 | Griffith Stadium (35-14) | 58-36 | |
| » Starters: Dolly Gray vs Lloyd Brown | Second | 11 out |
| Monday, July 27 |
| » Defeated Indians (45-50), 11-7 | Griffith Stadium (36-14) | 59-36 | |
| » Starters: Willis Hudlin vs Alvin Crowder | Second | 11 out |
| Tuesday, July 28 |
| » Defeated Indians (45-51), 8-1 | Griffith Stadium (37-14) | 60-36 | Won 2 |
| » Starters: Clint Brown vs Sam Jones | Second | 11 out |
| Wednesday, July 29 |
| » Lost to Indians (46-51), 6-0 | Griffith Stadium (37-15) | 60-37 | |
| » Starters: Wes Ferrell vs Firpo Marberry | Second | 12 out |
| Thursday, July 30 |
| » Defeated Indians (46-52), 6-1 | Griffith Stadium (38-15) | 61-37 | |
| » Starters: Mel Harder vs Carl Fischer | Second | 12 out |
| Saturday, August 1 |
| » Defeated Athletics (74-27), 2-1 | Griffith Stadium (39-15) | 62-37 | Won 2 |
| » Starters: Rube Walberg vs Firpo Marberry | Second | 11 out |
| Sunday, August 2 |
| » Defeated Athletics (74-28), 10-6 | Griffith Stadium (40-15) | 63-37 | Won 3 |
| » Starters: Hank McDonald vs Sam Jones | Second | 10 out |
| Monday, August 3 |
| » Lost to Athletics (75-28), 3-2 | Shibe Park (1-5) | 63-38 | |
| » Starters: Sam Jones vs Lefty Grove | Second | 12 out |
| » Lost to Athletics (76-28), 6-5 | Shibe Park (1-6) | 63-39 | Lost 2 |
| » Starters: Carl Fischer vs George Earnshaw | Second | 12 out |
| Thursday, August 6 |
| » Defeated Red Sox (41-63), 15-1 | Griffith Stadium (41-15) | 64-39 | |
| » Starters: Jack Russell vs Firpo Marberry | Second | 11 out |
| Saturday, August 8 |
| » Defeated Red Sox (41-64), 5-0 | Griffith Stadium (42-15) | 65-39 | Won 2 |
| » Starters: Wilcy Moore vs Bobby Burke | Second | 10 out |
| Sunday, August 9 |
| » Defeated Red Sox (41-65), 4-3 | Griffith Stadium (43-15) | 66-39 | Won 3 |
| » Starters: Milt Gaston vs Bump Hadley | Second | 10 out |
| Tuesday, August 11 |
| » Defeated White Sox (42-65), 3-0 | Comiskey Park I (5-3) | 67-39 | Won 4 |
| » Starters: Firpo Marberry vs Red Faber | Second | 10 out |
| Wednesday, August 12 |
| » Lost to White Sox (43-65), 11-1 | Comiskey Park I (5-4) | 67-40 | |
| » Starters: Alvin Crowder vs Vic Frasier | Second | 10 out |
| Thursday, August 13 |
| » Lost to White Sox (44-65), 10-8 | Comiskey Park I (5-5) | 67-41 | Lost 2 |
| » Starters: Bobby Burke vs Tommy Thomas | Second | 11 out |
| Friday, August 14 |
| » Lost to White Sox (45-65), 5-4 | Comiskey Park I (5-6) | 67-42 | Lost 3 |
| » Starters: Sam Jones vs Bob Weiland | Second | 11½ out |
| Saturday, August 15 |
| » Defeated Browns (47-63), 3-2 | Sportsman's Park III (5-3) | 68-42 | |
| » Starters: Bobby Burke vs Lefty Stewart | Second | 11½ out |
| Sunday, August 16 |
| » Defeated Browns (47-64), 5-3 | Sportsman's Park III (6-3) | 69-42 | Won 2 |
| » Starters: Firpo Marberry vs Dolly Gray | Second | 11 out |
| » Defeated Browns (47-65), 8-6 | Sportsman's Park III (7-3) | 70-42 | Won 3 |
| » Starters: Lloyd Brown vs George Blaeholder | Second | 11 out |
| Future Senator Don Rudolph is born in Baltimore, MD. |
| Tuesday, August 18 |
| » Lost to Browns (48-65), 4-2 | Sportsman's Park III (7-4) | 70-43 | |
| » Starters: Bump Hadley vs Dick Coffman | Second | 11½ out |
| Wednesday, August 19 |
| » Lost to Indians (54-59), 10-5 | League Park II (4-3) | 70-44 | Lost 2 |
| » Starters: Sam Jones vs Wes Ferrell | Second | 13 out |
| » Lost to Indians (55-59), 10-8 | League Park II (4-4) | 70-45 | Lost 3 |
| » Starters: Bobby Burke vs Willis Hudlin | Second | 13 out |
| Thursday, August 20 |
| » Lost to Indians (56-59), 10-8 | League Park II (4-5) | 70-46 | Lost 4 |
| » Starters: Firpo Marberry vs Mel Harder | Second | 13 out |
| Friday, August 21 |
| » Defeated Indians (56-60), 6-3 | League Park II (5-5) | 71-46 | |
| » Starters: Lloyd Brown vs Clint Brown | Second | 13 out |
| Saturday, August 22 |
| » Lost to Indians (57-60), 5-2 | League Park II (5-6) | 71-47 | |
| » Starters: Carl Fischer vs Wes Ferrell | Second | 14 out |
| Sunday, August 23 |
| » Defeated Tigers (47-73), 6-5 | Tiger Stadium (6-2) | 72-47 | |
| » Starters: Bobby Burke vs Earl Whitehill | Second | 13½ out |
| Monday, August 24 |
| » Lost to Tigers (48-73), 6-5 | Tiger Stadium (6-3) | 72-48 | |
| » Starters: Firpo Marberry vs Chief Hogsett | Second | 14½ out |
| Tuesday, August 25 |
| » Defeated Tigers (48-74), 5-1 | Tiger Stadium (7-3) | 73-48 | |
| » Starters: Lloyd Brown vs Art Herring | Second | 14½ out |
| Wednesday, August 26 |
| » Lost to Tigers (49-74), 5-4 | Tiger Stadium (7-4) | 73-49 | |
| » Starters: Sam Jones vs Earl Whitehill | Second | 14½ out |
| Thursday, August 27 |
| Future Senator Joe Cunningham is born in Paterson, NJ. |
| Saturday, August 29 |
| » Lost to Red Sox (48-73), 3-1 | Fenway Park (4-4) | 73-50 | Lost 2 |
| » Starters: Firpo Marberry vs Ed Durham | Second | 16½ out |
| » Lost to Red Sox (49-73), 3-2 | Fenway Park (4-5) | 73-51 | Lost 3 |
| » Starters: Carl Fischer vs Jack Russell | Second | 16½ out |
| Sunday, August 30 |
| » Defeated Athletics (89-35), 5-1 | Griffith Stadium (44-15) | 74-51 | |
| » Starters: Eddie Rommel vs Alvin Crowder | Second | 15½ out |
| Monday, August 31 |
| » Defeated Yankees (73-53), 6-5 | Yankee Stadium (2-5) | 75-51 | Won 2 |
| » Starters: Lloyd Brown vs Herb Pennock | Second | 15½ out |
| Tuesday, September 1 |
| » Defeated Athletics (90-36), 5-1 | Shibe Park (2-6) | 76-51 | Won 3 |
| » Starters: Sam Jones vs Rube Walberg | Second | 14½ out |
| Wednesday, September 2 |
| » Defeated Athletics (90-37), 5-2 | Shibe Park (3-6) | 77-51 | Won 4 |
| » Starters: Alvin Crowder vs Roy Mahaffey | Second | 13½ out |
| Friday, September 4 |
| » Defeated Yankees (76-54), 5-4 | Griffith Stadium (45-15) | 78-51 | Won 5 |
| » Starters: Hank Johnson vs Firpo Marberry | Second | 14 out |
| Saturday, September 5 |
| » Lost to Yankees (77-54), 7-0 | Griffith Stadium (45-16) | 78-52 | |
| » Starters: Lefty Gomez vs Carl Fischer | Second | 15 out |
| » Lost to Yankees (78-54), 7-3 | Griffith Stadium (45-17) | 78-53 | Lost 2 |
| » Starters: Red Ruffing vs Lloyd Brown | Second | 15 out |
| Sunday, September 6 |
| » Defeated Yankees (78-55), 4-1 | Griffith Stadium (46-17) | 79-53 | |
| » Starters: Herb Pennock vs Alvin Crowder | Second | 15 out |
| Monday, September 7 |
| » Defeated Red Sox (50-83), 7-5 | Fenway Park (5-5) | 80-53 | Won 2 |
| » Starters: Bobby Burke vs Ed Durham | Second | 13 out |
| » Defeated Red Sox (50-84), 15-1 | Fenway Park (6-5) | 81-53 | Won 3 |
| » Starters: Firpo Marberry vs Jack Russell | Second | 13 out |
| Tuesday, September 8 |
| » Lost to Athletics (95-40), 10-1 | Shibe Park (3-7) | 81-54 | |
| » Starters: Sam Jones vs Lefty Grove | Second | 14 out |
| Wednesday, September 9 |
| » Defeated Athletics (95-41), 2-1 | Shibe Park (4-7) | 82-54 | |
| » Starters: Alvin Crowder vs Rube Walberg | Second | 13 out |
| Thursday, September 10 |
| » Defeated Indians (70-65), 5-3 | Griffith Stadium (47-17) | 83-54 | Won 2 |
| » Starters: Mel Harder vs Lloyd Brown | Second | 13 out |
| Saturday, September 12 |
| » Lost to Indians (71-65), 7-4 | Griffith Stadium (47-18) | 83-55 | |
| » Starters: Wes Ferrell vs Sam Jones | Second | 13½ out |
| Sunday, September 13 |
| » Defeated Indians (71-66), 7-1 | Griffith Stadium (48-18) | 84-55 | |
| » Starters: Sarge Connally vs Alvin Crowder | Second | 13 out |
| Monday, September 14 |
| » Defeated Browns (58-83), 6-3 | Griffith Stadium (49-18) | 85-55 | Won 2 |
| » Starters: Lefty Stewart vs Firpo Marberry | Second | 12½ out |
| Tuesday, September 15 |
| » Lost to Browns (59-83), 5-4 | Griffith Stadium (49-19) | 85-56 | |
| » Starters: Bob Cooney vs Lloyd Brown | Second | 13½ out |
| Wednesday, September 16 |
| » Defeated Browns (59-84), 6-2 | Griffith Stadium (50-19) | 86-56 | |
| » Starters: Dick Coffman vs Alvin Crowder | Second | 13½ out |
| Thursday, September 17 |
| » Lost to Tigers (58-86), 3-1 | Griffith Stadium (50-20) | 86-57 | |
| » Starters: Art Herring vs Carl Fischer | Second | 14 out |
| » Major-league debuts: Babe Phelps (Senators) |
| Friday, September 18 |
| » Defeated Tigers (58-87), 4-3 | Griffith Stadium (51-20) | 87-57 | |
| » Starters: Earl Whitehill vs Firpo Marberry | Second | 14 out |
| Saturday, September 19 |
| » Lost to Tigers (59-87), 3-2 | Griffith Stadium (51-21) | 87-58 | |
| » Starters: Vic Sorrell vs Lloyd Brown | Third | 15½ out |
| Sunday, September 20 |
| » Defeated White Sox (55-91), 4-3 | Griffith Stadium (52-21) | 88-58 | |
| » Starters: Vic Frasier vs Alvin Crowder | Third | 14½ out |
| » Defeated White Sox (55-92), 6-4 | Griffith Stadium (53-21) | 89-58 | Won 2 |
| » Starters: Lou Garland vs Monte Weaver | Third | 14½ out |
| » Major-league debuts: Monte Weaver (Senators) |
| Monday, September 21 |
| » Defeated White Sox (55-93), 5-3 | Griffith Stadium (54-21) | 90-58 | Won 3 |
| » Starters: Ted Lyons vs Bump Hadley | Second | 14 out |
| Tuesday, September 22 |
| » Defeated White Sox (55-94), 7-2 | Griffith Stadium (55-21) | 91-58 | Won 4 |
| » Starters: Red Faber vs Carl Fischer | Second | 14 out |
| Future Senator Ken Aspromonte is born in Brooklyn, NY. |
| Wednesday, September 23 |
| » Defeated Yankees (90-59), 3-2 | Yankee Stadium (3-5) | 92-58 | Won 5 |
| » Starters: Lloyd Brown vs Lefty Gomez | Second | 13½ out |
| Friday, September 25 |
| » Lost to Yankees (91-59), 8-3 | Yankee Stadium (3-6) | 92-59 | |
| » Starters: Alvin Crowder vs Herb Pennock | Second | 15 out |
| Saturday, September 26 |
| » Lost to Yankees (92-59), 7-2 | Yankee Stadium (3-7) | 92-60 | Lost 2 |
| » Starters: Bump Hadley vs Lefty Gomez | Third | 16 out |
| » Lost to Yankees (93-59), 8-3 | Yankee Stadium (3-8) | 92-61 | Lost 3 |
| » Starters: Lloyd Brown vs Red Ruffing | Third | 16 out |
| Sunday, September 27 |
| » Lost to Red Sox (62-90), 4-2 | Griffith Stadium (55-22) | 92-62 | Lost 4 |
| » Starters: Jack Russell vs Ad Liska | Third | 16 out |
| Friday, October 16 |
| Future Senator Dave Sisler is born in St. Louis, MO. |
| Monday, October 19 |
| Future Senator Don Leppert is born in Indianapolis, IN. |
| Sunday, November 1 |
| Future Senator Russ Kemmerer is born in Pittsburgh, PA. |
| Monday, November 9 |
| Future Senator Whitey Herzog is born in New Athens, IL. |
| Wednesday, November 11 |
| Future Senator Dutch Dotterer is born in Syracuse, NY. |
| Tuesday, November 24 |
| Future Senator Dick Phillips is born in Racine, WI. |
| Wednesday, December 16 |
| Future Senator Neil Chrisley is born in Calhoun Falls, SC. |
| Sunday, December 20 |
| Future Senator Julio Becquer is born in Havana, Cuba. |
Game information provided by Retrosheet (www.retrosheet.org) |