| Sunday, February 1 |
| Future Red Sox Bob Smith is born in Woodsville, NH. |
| Sunday, February 22 |
| Future Red Sox Chet Nichols is born in Pawtucket, RI. |
| Tuesday, April 14 |
| » Lost to Yankees (1-0), 6-3 | Yankee Stadium (0-1) | 0-1 | |
| » Starters: Wilcy Moore vs Red Ruffing | Second | 1 out |
| Wednesday, April 15 |
| » Lost to Yankees (2-0), 8-7 | Yankee Stadium (0-2) | 0-2 | Lost 2 |
| » Starters: Danny MacFayden vs Hank Johnson | Third | 2 out |
| » Major-league debuts: Myril Hoag (Yankees) |
| Thursday, April 16 |
| » Lost to Yankees (3-0), 2-1 | Yankee Stadium (0-3) | 0-3 | Lost 3 |
| » Starters: Hod Lisenbee vs Herb Pennock | Fourth | 3 out |
| Saturday, April 18 |
| » Defeated Yankees (3-1), 5-4 | Yankee Stadium (1-3) | 1-3 | |
| » Starters: Milt Gaston vs Roy Sherid | Second | 2 out |
| » Major-league debuts: Urbane Pickering (Red Sox) |
| Sunday, April 19 |
| » Lost to Senators (4-1), 8-0 | Griffith Stadium (0-1) | 1-4 | |
| » Starters: Danny MacFayden vs Lloyd Brown | Fourth | 3 out |
| Monday, April 20 |
| » Defeated Senators (4-2), 13-3 | Griffith Stadium (1-1) | 2-4 | |
| » Starters: Jack Russell vs Alvin Crowder | Fourth | 2 out |
| » Major-league debuts: Cliff Bolton (Senators) |
| Tuesday, April 21 |
| » Lost to Senators (5-2), 12-3 | Griffith Stadium (1-2) | 2-5 | |
| » Starters: Milt Gaston vs Firpo Marberry | Fourth | 3 out |
| Wednesday, April 22 |
| » Lost to Yankees (6-2), 7-5 | Fenway Park (0-1) | 2-6 | Lost 2 |
| » Starters: Roy Sherid vs Hod Lisenbee | Seventh | 4 out |
| » Major-league debuts: Gene Rye (Red Sox) |
| Friday, April 24 |
| » Lost to Yankees (7-2), 7-4 | Fenway Park (0-2) | 2-7 | Lost 3 |
| » Starters: Red Ruffing vs Wilcy Moore | Seventh | 5 out |
| Saturday, April 25 |
| » Defeated Yankees (7-3), 5-4 | Fenway Park (1-2) | 3-7 | |
| » Starters: Lefty Gomez vs Ed Morris | Fourth | 4 out |
| Tuesday, April 28 |
| » Major-league debuts: Dixie Walker (Yankees) |
| Friday, May 1 |
| » Defeated Senators (8-6), 10-4 | Fenway Park (2-2) | 4-7 | Won 2 |
| » Starters: Alvin Crowder vs Jack Russell | Sixth | 3½ out |
| Saturday, May 2 |
| » Lost to Senators (9-6), 6-2 | Fenway Park (2-3) | 4-8 | |
| » Starters: Carl Fischer vs Danny MacFayden | Seventh | 4 out |
| » Defeated Senators (9-7), 3-2 | Fenway Park (3-3) | 5-8 | |
| » Starters: Firpo Marberry vs Ed Morris | Seventh | 4 out |
| Sunday, May 3 |
| » Lost to Yankees (9-7), 8-3 | Yankee Stadium (1-4) | 5-9 | |
| » Starters: Hod Lisenbee vs Roy Sherid | Seventh | 5 out |
| Monday, May 4 |
| » Defeated Athletics (7-7), 7-5 | Shibe Park (1-0) | 6-9 | |
| » Starters: Milt Gaston vs Hank McDonald | Seventh | 4 out |
| Tuesday, May 5 |
| » Lost to Athletics (8-7), 4-1 | Shibe Park (1-1) | 6-10 | |
| » Starters: Ed Durham vs George Earnshaw | Seventh | 5 out |
| Wednesday, May 6 |
| » Lost to Athletics (9-7), 10-3 | Shibe Park (1-2) | 6-11 | Lost 2 |
| » Starters: Jack Russell vs Eddie Rommel | Sixth | 5½ out |
| Friday, May 8 |
| » Defeated Indians (12-8), 8-4 | League Park II (1-0) | 7-11 | |
| » Starters: Danny MacFayden vs Wes Ferrell | Seventh | 4 out |
| Saturday, May 9 |
| » Defeated Indians (12-9), 5-1 | League Park II (2-0) | 8-11 | Won 2 |
| » Starters: Milt Gaston vs Willis Hudlin | Seventh | 3½ out |
| Sunday, May 10 |
| » Defeated Indians (12-10), 9-4 | League Park II (3-0) | 9-11 | Won 3 |
| » Starters: Ed Durham vs Mel Harder | Sixth | 3 out |
| Tuesday, May 12 |
| » Lost to Tigers (13-12), 2-0 | Tiger Stadium (0-1) | 9-12 | |
| » Starters: Jack Russell vs Vic Sorrell | Sixth | 3½ out |
| Wednesday, May 13 |
| » Lost to Tigers (14-12), 2-1 | Tiger Stadium (0-2) | 9-13 | Lost 2 |
| » Starters: Milt Gaston vs Earl Whitehill | Sixth | 4½ out |
| Thursday, May 14 |
| » Defeated Tigers (14-13), 4-3 | Tiger Stadium (1-2) | 10-13 | |
| » Starters: Ed Durham vs Waite Hoyt | Sixth | 4½ out |
| Friday, May 15 |
| » Defeated White Sox (9-15), 12-8 | Comiskey Park I (1-0) | 11-13 | Won 2 |
| » Starters: Danny MacFayden vs Red Faber | Sixth | 4½ out |
| Saturday, May 16 |
| » Lost to White Sox (10-15), 3-0 | Comiskey Park I (1-1) | 11-14 | |
| » Starters: Jack Russell vs Pat Caraway | Sixth | 5½ out |
| Sunday, May 17 |
| » Lost to White Sox (11-15), 2-1 | Comiskey Park I (1-2) | 11-15 | Lost 2 |
| » Starters: Milt Gaston vs Tommy Thomas | Sixth | 6½ out |
| Monday, May 18 |
| » Lost to White Sox (12-15), 9-8 | Comiskey Park I (1-3) | 11-16 | Lost 3 |
| » Starters: Hod Lisenbee vs Ted Lyons | Seventh | 7½ out |
| Wednesday, May 20 |
| » Lost to Browns (8-17), 8-4 | Sportsman's Park III (0-1) | 11-17 | Lost 4 |
| » Starters: Milt Gaston vs Lefty Stewart | Seventh | 9 out |
| Thursday, May 21 |
| » Lost to Browns (9-17), 2-1 | Sportsman's Park III (0-2) | 11-18 | Lost 5 |
| » Starters: Jack Russell vs Rip Collins | Seventh | 10 out |
| Saturday, May 23 |
| » Lost to Athletics (21-7), 7-1 | Shibe Park (1-3) | 11-19 | Lost 6 |
| » Starters: Ed Durham vs George Earnshaw | Eighth | 11 out |
| Sunday, May 24 |
| » Lost to Senators (20-13), 10-9 | Griffith Stadium (1-3) | 11-20 | Lost 7 |
| » Starters: Danny MacFayden vs Alvin Crowder | Eighth | 12 out |
| Tuesday, May 26 |
| » Defeated Senators (20-14), 6-4 | Fenway Park (4-3) | 12-20 | |
| » Starters: Sam Jones vs Jack Russell | Seventh | 12 out |
| Wednesday, May 27 |
| » Lost to Senators (21-14), 11-3 | Fenway Park (4-4) | 12-21 | |
| » Starters: Lloyd Brown vs Hod Lisenbee | Eighth | 13½ out |
| » Lost to Senators (22-14), 4-3 | Fenway Park (4-5) | 12-22 | Lost 2 |
| » Starters: Carl Fischer vs Ed Morris | Eighth | 13½ out |
| Thursday, May 28 |
| » Lost to Senators (23-14), 4-3 | Fenway Park (4-6) | 12-23 | Lost 3 |
| » Starters: Alvin Crowder vs Danny MacFayden | Eighth | 14½ out |
| Saturday, May 30 |
| » Lost to Athletics (27-8), 5-0 | Fenway Park (4-7) | 12-24 | Lost 4 |
| » Starters: Lefty Grove vs Jack Russell | Eighth | 14½ out |
| » Defeated Athletics (27-9), 6-5 | Fenway Park (5-7) | 13-24 | |
| » Starters: Roy Mahaffey vs Ed Durham | Eighth | 14½ out |
| Sunday, May 31 |
| » Lost to Athletics (28-9), 7-4 | Braves Field (0-1) | 13-25 | |
| » Starters: George Earnshaw vs Milt Gaston | Eighth | 14½ out |
| » Defeated Athletics (28-10), 7-3 | Braves Field (1-1) | 14-25 | |
| » Starters: Hank McDonald vs Ed Morris | Eighth | 14½ out |
| Tuesday, June 2 |
| » Lost to Indians (21-20), 12-11 | Fenway Park (5-8) | 14-26 | |
| » Starters: Mel Harder vs Danny MacFayden | Eighth | 15½ out |
| Wednesday, June 3 |
| » Lost to Indians (22-20), 5-4 | Fenway Park (5-9) | 14-27 | Lost 2 |
| » Starters: Clint Brown vs Jim Brillheart | Eighth | 16½ out |
| Thursday, June 4 |
| » Lost to Indians (23-20), 10-2 | Fenway Park (5-10) | 14-28 | Lost 3 |
| » Starters: Wes Ferrell vs Jack Russell | Eighth | 17½ out |
| Friday, June 5 |
| » Defeated Indians (23-21), 4-3 | Fenway Park (6-10) | 15-28 | |
| » Starters: Willis Hudlin vs Ed Morris | Eighth | 16½ out |
| Saturday, June 6 |
| » Defeated Browns (15-25), 9-8 | Fenway Park (7-10) | 16-28 | Won 2 |
| » Starters: Dick Coffman vs Bob Kline | Eighth | 16½ out |
| Sunday, June 7 |
| » Defeated Browns (15-26), 6-3 | Braves Field (2-1) | 17-28 | Won 3 |
| » Starters: Rip Collins vs Danny MacFayden | Seventh | 16½ out |
| Monday, June 8 |
| » Lost to Browns (16-26), 4-0 | Fenway Park (7-11) | 17-29 | |
| » Starters: Lefty Stewart vs Milt Gaston | Eighth | 17½ out |
| Tuesday, June 9 |
| » Major-league debuts: Billy Sullivan (White Sox) |
| Friday, June 12 |
| » Defeated Tigers (19-34), 3-1 | Fenway Park (8-11) | 18-29 | |
| » Starters: George Uhle vs Jack Russell | Sixth | 17½ out |
| Saturday, June 13 |
| » Defeated Tigers (19-35), 7-1 | Fenway Park (9-11) | 19-29 | Won 2 |
| » Starters: Whit Wyatt vs Ed Morris | Fifth | 18 out |
| Sunday, June 14 |
| » Lost to White Sox (19-30), 7-4 | Braves Field (2-2) | 19-30 | |
| » Starters: Tommy Thomas vs Danny MacFayden | Fifth | 18 out |
| Monday, June 15 |
| » Defeated White Sox (19-31), 3-2 | Fenway Park (10-11) | 20-30 | |
| » Starters: Vic Frasier vs Bob Kline | Fifth | 18 out |
| Friday, June 19 |
| » Lost to Tigers (22-35), 7-6 | Tiger Stadium (1-3) | 20-31 | |
| » Starters: Jack Russell vs George Uhle | Fifth | 19½ out |
| Saturday, June 20 |
| » Lost to Tigers (23-35), 5-4 | Tiger Stadium (1-4) | 20-32 | Lost 2 |
| » Starters: Ed Morris vs Vic Sorrell | Sixth | 20½ out |
| Sunday, June 21 |
| » Defeated Tigers (23-36), 7-6 | Tiger Stadium (2-4) | 21-32 | |
| » Starters: Bob Kline vs Earl Whitehill | Fifth | 20½ out |
| Monday, June 22 |
| » Defeated Tigers (23-37), 7-2 | Tiger Stadium (3-4) | 22-32 | Won 2 |
| » Starters: Danny MacFayden vs Tommy Bridges | Fifth | 19½ out |
| Future Red Sox Faye Throneberry is born in Fisherville, TN. |
| Tuesday, June 23 |
| » Lost to Indians (29-30), 13-0 | League Park II (3-1) | 22-33 | |
| » Starters: Jack Russell vs Clint Brown | Fifth | 20½ out |
| » Lost to Indians (30-30), 10-0 | League Park II (3-2) | 22-34 | Lost 2 |
| » Starters: Ed Morris vs Willis Hudlin | Fifth | 20½ out |
| Wednesday, June 24 |
| » Defeated Indians (30-31), 7-3 | League Park II (4-2) | 23-34 | |
| » Starters: Wilcy Moore vs Mel Harder | Fifth | 19½ out |
| Thursday, June 25 |
| » Defeated Indians (30-32), 8-3 | League Park II (5-2) | 24-34 | Won 2 |
| » Starters: Bob Kline vs Roxie Lawson | Fifth | 18 out |
| Friday, June 26 |
| » Lost to Browns (25-36), 3-2 | Sportsman's Park III (0-3) | 24-35 | |
| » Starters: Danny MacFayden vs Rip Collins | Sixth | 18½ out |
| Saturday, June 27 |
| » Lost to Browns (26-36), 5-4 | Sportsman's Park III (0-4) | 24-36 | Lost 2 |
| » Starters: Jack Russell vs George Blaeholder | Sixth | 19½ out |
| Sunday, June 28 |
| » Lost to Browns (27-36), 5-4 | Sportsman's Park III (0-5) | 24-37 | Lost 3 |
| » Starters: Ed Morris vs Dolly Gray | Sixth | 21½ out |
| » Lost to Browns (28-36), 5-4 | Sportsman's Park III (0-6) | 24-38 | Lost 4 |
| » Starters: Ed Durham vs Wally Hebert | Sixth | 21½ out |
| Monday, June 29 |
| » Defeated Browns (28-37), 4-2 | Sportsman's Park III (1-6) | 25-38 | |
| » Starters: Wilcy Moore vs Lefty Stewart | Sixth | 20½ out |
| Tuesday, June 30 |
| » Defeated White Sox (23-42), 7-1 | Comiskey Park I (2-3) | 26-38 | Won 2 |
| » Starters: Danny MacFayden vs Pat Caraway | Sixth | 20½ out |
| Wednesday, July 1 |
| » Defeated White Sox (23-43), 5-3 | Comiskey Park I (3-3) | 27-38 | Won 3 |
| » Starters: Jack Russell vs Jim Moore | Sixth | 20½ out |
| Thursday, July 2 |
| » Lost to White Sox (24-43), 2-0 | Comiskey Park I (3-4) | 27-39 | |
| » Starters: Bob Kline vs Tommy Thomas | Sixth | 20½ out |
| Saturday, July 4 |
| » Lost to Athletics (50-20), 9-7 | Shibe Park (1-4) | 27-40 | Lost 2 |
| » Starters: Ed Morris vs Roy Mahaffey | Sixth | 22½ out |
| » Lost to Athletics (51-20), 6-2 | Shibe Park (1-5) | 27-41 | Lost 3 |
| » Starters: Wilcy Moore vs Waite Hoyt | Sixth | 22½ out |
| Sunday, July 5 |
| » Defeated Yankees (39-31), 6-3 | Yankee Stadium (2-4) | 28-41 | |
| » Starters: Danny MacFayden vs Red Ruffing | Sixth | 21½ out |
| Wednesday, July 8 |
| » Lost to Yankees (40-31), 13-3 | Yankee Stadium (2-5) | 28-42 | |
| » Starters: Jack Russell vs Jim Weaver | Sixth | 23½ out |
| » Lost to Yankees (41-31), 9-4 | Yankee Stadium (2-6) | 28-43 | Lost 2 |
| » Starters: Bob Kline vs Herb Pennock | Sixth | 23½ out |
| Thursday, July 9 |
| » Lost to Senators (49-29), 14-1 | Griffith Stadium (1-4) | 28-44 | Lost 3 |
| » Starters: Wilcy Moore vs Firpo Marberry | Sixth | 23½ out |
| Saturday, July 11 |
| » Lost to Senators (50-29), 7-1 | Griffith Stadium (1-5) | 28-45 | Lost 4 |
| » Starters: Danny MacFayden vs Lloyd Brown | Seventh | 24½ out |
| » Lost to Senators (51-29), 8-7 | Griffith Stadium (1-6) | 28-46 | Lost 5 |
| » Starters: Jack Russell vs Carl Fischer | Seventh | 24½ out |
| Sunday, July 12 |
| » Lost to Athletics (55-23), 7-2 | Braves Field (2-3) | 28-47 | Lost 6 |
| » Starters: Waite Hoyt vs Wilcy Moore | Eighth | 26½ out |
| » Lost to Athletics (56-23), 6-2 | Braves Field (2-4) | 28-48 | Lost 7 |
| » Starters: Roy Mahaffey vs Ed Morris | Eighth | 26½ out |
| Tuesday, July 14 |
| » Lost to Browns (36-44), 5-3 | Fenway Park (10-12) | 28-49 | Lost 8 |
| » Starters: Rip Collins vs Milt Gaston | Eighth | 26½ out |
| Wednesday, July 15 |
| » Defeated Browns (36-45), 5-4 | Fenway Park (11-12) | 29-49 | |
| » Starters: Lefty Stewart vs Danny MacFayden | Eighth | 27½ out |
| » Lost to Browns (37-45), 5-2 | Fenway Park (11-13) | 29-50 | |
| » Starters: George Blaeholder vs Jack Russell | Eighth | 27½ out |
| Thursday, July 16 |
| » Lost to Browns (38-45), 2-1 | Fenway Park (11-14) | 29-51 | Lost 2 |
| » Starters: Dolly Gray vs Hod Lisenbee | Eighth | 28½ out |
| Friday, July 17 |
| » Lost to Browns (39-45), 6-2 | Fenway Park (11-15) | 29-52 | Lost 3 |
| » Starters: Rip Collins vs Bob Kline | Eighth | 29½ out |
| Saturday, July 18 |
| » Defeated Indians (43-42), 4-1 | Fenway Park (12-15) | 30-52 | |
| » Starters: Mel Harder vs Danny MacFayden | Seventh | 30 out |
| Sunday, July 19 |
| » Defeated Indians (43-43), 6-5 | Braves Field (3-4) | 31-52 | Won 2 |
| » Starters: Willis Hudlin vs Jack Russell | Sixth | 29½ out |
| Monday, July 20 |
| » Lost to Indians (44-43), 9-2 | Fenway Park (12-16) | 31-53 | |
| » Starters: Clint Brown vs Milt Gaston | Sixth | 30½ out |
| Tuesday, July 21 |
| » Defeated Indians (44-44), 3-2 | Fenway Park (13-16) | 32-53 | |
| » Starters: Wes Ferrell vs Hod Lisenbee | Sixth | 30½ out |
| Wednesday, July 22 |
| » Defeated White Sox (30-56), 3-2 | Fenway Park (14-16) | 33-53 | Won 2 |
| » Starters: Red Faber vs Danny MacFayden | Sixth | 31 out |
| » Lost to White Sox (31-56), 9-3 | Fenway Park (14-17) | 33-54 | |
| » Starters: Tommy Thomas vs Ed Morris | Sixth | 31 out |
| Thursday, July 23 |
| » Defeated White Sox (31-57), 13-4 | Fenway Park (15-17) | 34-54 | |
| » Starters: Pat Caraway vs Jack Russell | Sixth | 31 out |
| Friday, July 24 |
| » Lost to White Sox (32-57), 3-1 | Fenway Park (15-18) | 34-55 | |
| » Starters: Vic Frasier vs Hod Lisenbee | Sixth | 32 out |
| Saturday, July 25 |
| » Lost to White Sox (33-57), 7-5 | Fenway Park (15-19) | 34-56 | Lost 2 |
| » Starters: Ted Lyons vs Bob Kline | Sixth | 33½ out |
| Sunday, July 26 |
| » Defeated Tigers (34-61), 7-6 | Braves Field (4-4) | 35-56 | |
| » Starters: Art Herring vs Danny MacFayden | Sixth | 33 out |
| » Lost to Tigers (35-61), 7-3 | Braves Field (4-5) | 35-57 | |
| » Starters: Charlie Sullivan vs Jack Russell | Sixth | 33 out |
| Monday, July 27 |
| » Defeated Tigers (35-62), 13-4 | Fenway Park (16-19) | 36-57 | |
| » Starters: Tommy Bridges vs Danny MacFayden | Sixth | 33 out |
| Tuesday, July 28 |
| » Defeated Tigers (35-63), 8-1 | Fenway Park (17-19) | 37-57 | Won 2 |
| » Starters: Earl Whitehill vs Hod Lisenbee | Sixth | 33 out |
| Wednesday, July 29 |
| » Defeated Tigers (35-64), 5-4 | Fenway Park (18-19) | 38-57 | Won 3 |
| » Starters: George Uhle vs Jack Russell | Sixth | 33½ out |
| » Lost to Tigers (36-64), 8-6 | Fenway Park (18-20) | 38-58 | |
| » Starters: Chief Hogsett vs Bob Kline | Sixth | 33½ out |
| Friday, July 31 |
| » Lost to Yankees (57-39), 4-1 | Fenway Park (18-21) | 38-59 | Lost 2 |
| » Starters: Lefty Gomez vs Danny MacFayden | Sixth | 34½ out |
| Saturday, August 1 |
| » Defeated Yankees (57-40), 9-2 | Fenway Park (19-21) | 39-59 | |
| » Starters: Hank Johnson vs Hod Lisenbee | Sixth | 33½ out |
| Sunday, August 2 |
| » Lost to Yankees (58-40), 4-1 | Braves Field (4-6) | 39-60 | |
| » Starters: Red Ruffing vs Jack Russell | Sixth | 33 out |
| » Defeated Yankees (58-41), 1-0 | Braves Field (5-6) | 40-60 | |
| » Starters: George Pipgras vs Wilcy Moore | Sixth | 33 out |
| Monday, August 3 |
| » Lost to Yankees (59-41), 9-8 | Fenway Park (19-22) | 40-61 | |
| » Starters: Ed Wells vs Bob Kline | Sixth | 34½ out |
| Wednesday, August 5 |
| » Defeated Yankees (59-42), 5-1 | Fenway Park (20-22) | 41-61 | |
| » Starters: Herb Pennock vs Danny MacFayden | Sixth | 34½ out |
| » Lost to Yankees (60-42), 4-1 | Fenway Park (20-23) | 41-62 | |
| » Starters: Gordon Rhodes vs Hod Lisenbee | Sixth | 34½ out |
| Thursday, August 6 |
| » Lost to Senators (64-39), 15-1 | Griffith Stadium (1-7) | 41-63 | Lost 2 |
| » Starters: Jack Russell vs Firpo Marberry | Sixth | 34½ out |
| Saturday, August 8 |
| » Lost to Senators (65-39), 5-0 | Griffith Stadium (1-8) | 41-64 | Lost 3 |
| » Starters: Wilcy Moore vs Bobby Burke | Seventh | 34½ out |
| Sunday, August 9 |
| » Lost to Senators (66-39), 4-3 | Griffith Stadium (1-9) | 41-65 | Lost 4 |
| » Starters: Milt Gaston vs Bump Hadley | Seventh | 35½ out |
| Tuesday, August 11 |
| » Defeated Browns (45-61), 4-3 | Sportsman's Park III (2-6) | 42-65 | |
| » Starters: Danny MacFayden vs Rip Collins | Sixth | 35½ out |
| Wednesday, August 12 |
| » Defeated Browns (45-62), 6-5 | Sportsman's Park III (3-6) | 43-65 | Won 2 |
| » Starters: Hod Lisenbee vs Dolly Gray | Sixth | 34½ out |
| Thursday, August 13 |
| » Lost to Browns (46-62), 9-6 | Sportsman's Park III (3-7) | 43-66 | |
| » Starters: Wilcy Moore vs George Blaeholder | Seventh | 35½ out |
| Friday, August 14 |
| » Lost to Browns (47-62), 12-2 | Sportsman's Park III (3-8) | 43-67 | Lost 2 |
| » Starters: Milt Gaston vs Dick Coffman | Seventh | 36 out |
| Saturday, August 15 |
| » Defeated White Sox (45-66), 1-0 | Comiskey Park I (4-4) | 44-67 | |
| » Starters: Danny MacFayden vs Red Faber | Seventh | 36 out |
| Sunday, August 16 |
| » Lost to White Sox (46-66), 9-2 | Comiskey Park I (4-5) | 44-68 | |
| » Starters: Hod Lisenbee vs Tommy Thomas | Seventh | 36½ out |
| » Defeated White Sox (46-67), 5-1 | Comiskey Park I (5-5) | 45-68 | |
| » Starters: Ed Durham vs Vic Frasier | Seventh | 36½ out |
| Monday, August 17 |
| » Defeated White Sox (46-68), 3-2 | Comiskey Park I (6-5) | 46-68 | Won 2 |
| » Starters: Jack Russell vs Pat Caraway | Sixth | 36 out |
| Wednesday, August 19 |
| » Defeated Tigers (44-72), 9-8 | Tiger Stadium (4-4) | 47-68 | Won 3 |
| » Starters: Danny MacFayden vs Charlie Sullivan | Sixth | 36 out |
| Thursday, August 20 |
| » Lost to Tigers (45-72), 7-2 | Tiger Stadium (4-5) | 47-69 | |
| » Starters: Hod Lisenbee vs Art Herring | Sixth | 36 out |
| Friday, August 21 |
| » Lost to Tigers (46-72), 11-5 | Tiger Stadium (4-6) | 47-70 | Lost 2 |
| » Starters: Ed Durham vs George Uhle | Sixth | 37 out |
| Saturday, August 22 |
| » Lost to Tigers (47-72), 9-6 | Tiger Stadium (4-7) | 47-71 | Lost 3 |
| » Starters: Jack Russell vs Vic Sorrell | Sixth | 38 out |
| Sunday, August 23 |
| » Lost to Indians (58-60), 4-3 | League Park II (5-3) | 47-72 | Lost 4 |
| » Starters: Danny MacFayden vs Sarge Connally | Sixth | 38½ out |
| Monday, August 24 |
| » Lost to Indians (59-60), 11-7 | League Park II (5-4) | 47-73 | Lost 5 |
| » Starters: Milt Gaston vs Willis Hudlin | Seventh | 39½ out |
| Saturday, August 29 |
| » Defeated Senators (73-50), 3-1 | Fenway Park (21-23) | 48-73 | |
| » Starters: Firpo Marberry vs Ed Durham | Sixth | 39½ out |
| » Defeated Senators (73-51), 3-2 | Fenway Park (22-23) | 49-73 | Won 2 |
| » Starters: Carl Fischer vs Jack Russell | Sixth | 39½ out |
| Sunday, August 30 |
| » Lost to Yankees (73-52), 14-4 | Braves Field (5-7) | 49-74 | |
| » Starters: Hank Johnson vs Danny MacFayden | Sixth | 39½ out |
| Monday, August 31 |
| » Lost to Athletics (90-35), 3-0 | Shibe Park (1-6) | 49-75 | Lost 2 |
| » Starters: Wilcy Moore vs Waite Hoyt | Seventh | 40½ out |
| Tuesday, September 1 |
| » Lost to Yankees (74-53), 11-3 | Yankee Stadium (2-7) | 49-76 | Lost 3 |
| » Starters: Danny MacFayden vs Lefty Gomez | Eighth | 41 out |
| » Lost to Yankees (75-53), 5-1 | Yankee Stadium (2-8) | 49-77 | Lost 4 |
| » Starters: Ed Morris vs Red Ruffing | Eighth | 41 out |
| Wednesday, September 2 |
| » Lost to Yankees (76-53), 7-6 | Yankee Stadium (2-9) | 49-78 | Lost 5 |
| » Starters: Hod Lisenbee vs Gordon Rhodes | Eighth | 41 out |
| Thursday, September 3 |
| Future Red Sox Tom Brewer is born in Wadesboro, NC. |
| Friday, September 4 |
| » Lost to Athletics (91-37), 2-0 | Fenway Park (22-24) | 49-79 | Lost 6 |
| » Starters: Lefty Grove vs Ed Durham | Eighth | 43 out |
| » Lost to Athletics (92-37), 6-1 | Fenway Park (22-25) | 49-80 | Lost 7 |
| » Starters: Waite Hoyt vs Jack Russell | Eighth | 43 out |
| Saturday, September 5 |
| » Lost to Athletics (93-37), 8-0 | Fenway Park (22-26) | 49-81 | Lost 8 |
| » Starters: George Earnshaw vs Danny MacFayden | Seventh | 43 out |
| » Defeated Athletics (93-38), 6-3 | Fenway Park (23-26) | 50-81 | |
| » Starters: Rube Walberg vs Wilcy Moore | Seventh | 43 out |
| Sunday, September 6 |
| » Lost to Athletics (94-38), 5-3 | Braves Field (5-8) | 50-82 | |
| » Starters: Eddie Rommel vs Milt Gaston | Eighth | 44 out |
| Monday, September 7 |
| » Lost to Senators (80-53), 7-5 | Fenway Park (23-27) | 50-83 | Lost 2 |
| » Starters: Bobby Burke vs Ed Durham | Eighth | 44 out |
| » Lost to Senators (81-53), 15-1 | Fenway Park (23-28) | 50-84 | Lost 3 |
| » Starters: Firpo Marberry vs Jack Russell | Eighth | 44 out |
| Tuesday, September 8 |
| » Major-league debuts: Oral Hildebrand (Indians) |
| Thursday, September 10 |
| » Lost to Tigers (57-80), 3-0 | Fenway Park (23-29) | 50-85 | Lost 4 |
| » Starters: Tommy Bridges vs Wilcy Moore | Eighth | 45 out |
| Friday, September 11 |
| » Defeated Tigers (57-81), 5-0 | Fenway Park (24-29) | 51-85 | |
| » Starters: Orlin Collier vs Danny MacFayden | Seventh | 44½ out |
| Saturday, September 12 |
| » Defeated Tigers (57-82), 1-0 | Fenway Park (25-29) | 52-85 | Won 2 |
| » Starters: Art Herring vs Ed Durham | Eighth | 44 out |
| Sunday, September 13 |
| » Lost to White Sox (55-84), 6-5 | Braves Field (5-9) | 52-86 | |
| » Starters: Grant Bowler vs Jack Russell | Eighth | 44½ out |
| » Tied White Sox, 2-2 | Braves Field (5-9) | 52-86 | |
| » Starters: Jim Moore vs Milt Gaston | Eighth | 44½ out |
| Future Red Sox George Susce is born in Pittsburgh, PA. |
| Monday, September 14 |
| » Defeated White Sox (55-85), 12-8 | Fenway Park (26-29) | 53-86 | |
| » Starters: Tommy Thomas vs Hod Lisenbee | Eighth | 44 out |
| Tuesday, September 15 |
| » Defeated White Sox (55-86), 3-2 | Fenway Park (27-29) | 54-86 | Won 2 |
| » Starters: Ted Lyons vs Danny MacFayden | Eighth | 44 out |
| Wednesday, September 16 |
| » Defeated White Sox (55-87), 2-1 | Fenway Park (28-29) | 55-86 | Won 3 |
| » Starters: Vic Frasier vs Ed Durham | Seventh | 44 out |
| Thursday, September 17 |
| » Defeated Indians (72-70), 9-2 | Fenway Park (29-29) | 56-86 | Won 4 |
| » Starters: Sarge Connally vs Wilcy Moore | Sixth | 44 out |
| » Lost to Indians (73-70), 2-1 | Fenway Park (29-30) | 56-87 | |
| » Starters: Pete Appleton vs Milt Gaston | Sixth | 44 out |
| Friday, September 18 |
| » Defeated Indians (73-71), 6-1 | Fenway Park (30-30) | 57-87 | |
| » Starters: Willis Hudlin vs Jack Russell | Fifth | 43½ out |
| » Defeated Indians (73-72), 6-4 | Fenway Park (31-30) | 58-87 | Won 2 |
| » Starters: Clint Brown vs Hod Lisenbee | Fifth | 43½ out |
| Saturday, September 19 |
| » Defeated Indians (73-73), 2-1 | Fenway Park (32-30) | 59-87 | Won 3 |
| » Starters: Oral Hildebrand vs Danny MacFayden | Fifth | 44 out |
| Monday, September 21 |
| » Defeated Browns (59-89), 2-0 | Fenway Park (33-30) | 60-87 | Won 4 |
| » Starters: Dick Coffman vs Ed Durham | Fourth | 43 out |
| » Defeated Browns (59-90), 9-2 | Fenway Park (34-30) | 61-87 | Won 5 |
| » Starters: Dolly Gray vs Ed Morris | Fourth | 43 out |
| Tuesday, September 22 |
| » Lost to Browns (60-90), 5-2 | Fenway Park (34-31) | 61-88 | |
| » Starters: George Blaeholder vs Milt Gaston | Fifth | 44 out |
| Future Red Sox Ken Aspromonte is born in Brooklyn, NY. |
| Thursday, September 24 |
| » Lost to Athletics (106-44), 9-4 | Shibe Park (1-7) | 61-89 | Lost 2 |
| » Starters: Wilcy Moore vs Lefty Grove | Fifth | 45 out |
| Friday, September 25 |
| » Lost to Athletics (107-44), 7-1 | Shibe Park (1-8) | 61-90 | Lost 3 |
| » Starters: Ed Durham vs Lew Krausse | Fifth | 46 out |
| Sunday, September 27 |
| » Defeated Senators (92-62), 4-2 | Griffith Stadium (2-9) | 62-90 | |
| » Starters: Jack Russell vs Ad Liska | Sixth | 45 out |
| Friday, October 16 |
| Future Red Sox Dave Sisler is born in St. Louis, MO. |
| Sunday, November 1 |
| Future Red Sox Russ Kemmerer is born in Pittsburgh, PA. |
| Friday, November 6 |
| Former Red Sox Jack Chesbro dies in Conway, MA at the age of 58. |
Game information provided by Retrosheet (www.retrosheet.org) |
