| Tuesday, January 6 |
| Future Indian Dick Tomanek is born in Avon Lake, OH. |
| Saturday, January 31 |
| Future Indian Hank Aguirre is born in Azusa, CA. |
| Tuesday, April 14 |
| » Defeated White Sox (0-1), 5-4 | League Park II (1-0) | 1-0 | |
| » Starters: Tommy Thomas vs Wes Ferrell | First | -- |
| Wednesday, April 15 |
| » Lost to White Sox (1-1), 7-6 | League Park II (1-1) | 1-1 | |
| » Starters: Pat Caraway vs Willis Hudlin | Second | 1 out |
| Thursday, April 16 |
| » Defeated White Sox (1-2), 7-0 | League Park II (2-1) | 2-1 | |
| » Starters: Red Faber vs Clint Brown | Second | 1 out |
| Saturday, April 18 |
| » Defeated White Sox (1-3), 11-2 | League Park II (3-1) | 3-1 | Won 2 |
| » Starters: Vic Frasier vs Mel Harder | First | -- |
| » Major-league debuts: Vic Frasier (White Sox) |
| Sunday, April 19 |
| » Lost to Tigers (2-3), 7-2 | League Park II (3-2) | 3-2 | |
| » Starters: Earl Whitehill vs Wes Ferrell | Second | 1 out |
| Monday, April 20 |
| » Defeated Tigers (2-4), 9-3 | League Park II (4-2) | 4-2 | |
| » Starters: Waite Hoyt vs Willis Hudlin | First | -- |
| Tuesday, April 21 |
| » Defeated Tigers (2-5), 5-4 | League Park II (5-2) | 5-2 | Won 2 |
| » Starters: Vic Sorrell vs Clint Brown | First | -- |
| Wednesday, April 22 |
| » Lost to White Sox (3-3), 10-2 | Comiskey Park I (0-1) | 5-3 | |
| » Starters: Mel Harder vs Pat Caraway | Second | 1 out |
| Thursday, April 23 |
| » Defeated White Sox (3-4), 8-2 | Comiskey Park I (1-1) | 6-3 | |
| » Starters: Wes Ferrell vs Garland Braxton | Second | ½ out |
| Friday, April 24 |
| » Defeated White Sox (3-5), 8-1 | Comiskey Park I (2-1) | 7-3 | Won 2 |
| » Starters: Willis Hudlin vs Tommy Thomas | Second | ½ out |
| Tuesday, April 28 |
| » Defeated Browns (3-6), 10-9 | League Park II (6-2) | 8-3 | Won 3 |
| » Starters: George Blaeholder vs Clint Brown | First | -- |
| Wednesday, April 29 |
| » Defeated Browns (3-7), 9-0 | League Park II (7-2) | 9-3 | Won 4 |
| » Starters: Dolly Gray vs Wes Ferrell | First | -- |
| Thursday, April 30 |
| » Lost to Tigers (7-7), 9-4 | Tiger Stadium (0-1) | 9-4 | |
| » Starters: Willis Hudlin vs Waite Hoyt | First | -- |
| Friday, May 1 |
| » Lost to Tigers (8-7), 4-2 | Tiger Stadium (0-2) | 9-5 | Lost 2 |
| » Starters: Mel Harder vs Charlie Sullivan | First | -- |
| Saturday, May 2 |
| » Defeated Tigers (8-8), 3-1 | Tiger Stadium (1-2) | 10-5 | |
| » Starters: Clint Brown vs Vic Sorrell | First | -- |
| Sunday, May 3 |
| » Defeated Tigers (8-9), 7-4 | Tiger Stadium (2-2) | 11-5 | Won 2 |
| » Starters: Wes Ferrell vs Earl Whitehill | First | -- |
| Monday, May 4 |
| » Lost to Browns (5-10), 3-1 | Sportsman's Park III (0-1) | 11-6 | |
| » Starters: Willis Hudlin vs Lefty Stewart | First | -- |
| Tuesday, May 5 |
| » Defeated Browns (5-11), 11-6 | Sportsman's Park III (1-1) | 12-6 | |
| » Starters: Mel Harder vs Chad Kimsey | First | -- |
| Thursday, May 7 |
| » Lost to Browns (6-11), 10-4 | Sportsman's Park III (1-2) | 12-7 | |
| » Starters: Clint Brown vs George Blaeholder | First | -- |
| Friday, May 8 |
| » Lost to Red Sox (7-11), 8-4 | League Park II (7-3) | 12-8 | Lost 2 |
| » Starters: Danny MacFayden vs Wes Ferrell | First | -- |
| Saturday, May 9 |
| » Lost to Red Sox (8-11), 5-1 | League Park II (7-4) | 12-9 | Lost 3 |
| » Starters: Milt Gaston vs Willis Hudlin | Third | ½ out |
| Sunday, May 10 |
| » Lost to Red Sox (9-11), 9-4 | League Park II (7-5) | 12-10 | Lost 4 |
| » Starters: Ed Durham vs Mel Harder | Third | 1 out |
| Wednesday, May 13 |
| » Lost to Senators (13-11), 9-3 | League Park II (7-6) | 12-11 | Lost 5 |
| » Starters: Lloyd Brown vs Wes Ferrell | Fifth | 2 out |
| Thursday, May 14 |
| » Lost to Senators (14-11), 5-4 | League Park II (7-7) | 12-12 | Lost 6 |
| » Starters: Sam Jones vs Jake Miller | Fifth | 3 out |
| Friday, May 15 |
| » Lost to Athletics (14-7), 4-0 | League Park II (7-8) | 12-13 | Lost 7 |
| » Starters: Eddie Rommel vs Clint Brown | Fifth | 4 out |
| Saturday, May 16 |
| » Lost to Athletics (15-7), 12-5 | League Park II (7-9) | 12-14 | Lost 8 |
| » Starters: Lefty Grove vs Willis Hudlin | Fifth | 5 out |
| Sunday, May 17 |
| » Lost to Athletics (16-7), 15-10 | League Park II (7-10) | 12-15 | Lost 9 |
| » Starters: George Earnshaw vs Wes Ferrell | Fifth | 6 out |
| Monday, May 18 |
| » Lost to Athletics (17-7), 10-7 | League Park II (7-11) | 12-16 | Lost 10 |
| » Starters: Rube Walberg vs Jake Miller | Sixth | 7 out |
| Tuesday, May 19 |
| » Lost to Yankees (17-10), 8-6 | League Park II (7-12) | 12-17 | Lost 11 |
| » Starters: Red Ruffing vs Clint Brown | Sixth | 8 out |
| Thursday, May 21 |
| » Lost to Yankees (18-10), 7-6 | League Park II (7-13) | 12-18 | Lost 12 |
| » Starters: George Pipgras vs Willis Hudlin | Sixth | 9½ out |
| Saturday, May 23 |
| » Defeated White Sox (12-18), 10-5 | League Park II (8-13) | 13-18 | |
| » Starters: Vic Frasier vs Wes Ferrell | Fifth | 9½ out |
| Sunday, May 24 |
| » Lost to White Sox (13-18), 4-3 | League Park II (8-14) | 13-19 | |
| » Starters: Ted Lyons vs Clint Brown | Seventh | 11 out |
| » Lost to White Sox (14-18), 3-2 | League Park II (8-15) | 13-20 | Lost 2 |
| » Starters: Pat Caraway vs Fay Thomas | Seventh | 11 out |
| Monday, May 25 |
| » Defeated White Sox (14-19), 7-6 | League Park II (9-15) | 14-20 | |
| » Starters: Tommy Thomas vs Willis Hudlin | Sixth | 11½ out |
| Tuesday, May 26 |
| » Defeated Browns (12-19), 12-0 | League Park II (10-15) | 15-20 | Won 2 |
| » Starters: George Blaeholder vs Jake Miller | Fifth | 10 out |
| » Defeated Browns (12-20), 4-2 | League Park II (11-15) | 16-20 | Won 3 |
| » Starters: Rip Collins vs Mel Harder | Fifth | 10 out |
| Wednesday, May 27 |
| » Defeated Browns (12-21), 5-4 | League Park II (12-15) | 17-20 | Won 4 |
| » Starters: Dolly Gray vs Wes Ferrell | Fourth | 10 out |
| Thursday, May 28 |
| » Defeated Browns (12-22), 5-4 | League Park II (13-15) | 18-20 | Won 5 |
| » Starters: Lefty Stewart vs Fay Thomas | Fourth | 10 out |
| Friday, May 29 |
| » Defeated Tigers (18-25), 9-2 | Tiger Stadium (3-2) | 19-20 | Won 6 |
| » Starters: Clint Brown vs Tommy Bridges | Fourth | 9½ out |
| Sunday, May 31 |
| » Defeated Tigers (18-26), 6-4 | Tiger Stadium (4-2) | 20-20 | Won 7 |
| » Starters: Willis Hudlin vs George Uhle | Fourth | 9 out |
| Tuesday, June 2 |
| » Defeated Red Sox (14-26), 12-11 | Fenway Park (1-0) | 21-20 | Won 8 |
| » Starters: Mel Harder vs Danny MacFayden | Fourth | 9 out |
| Wednesday, June 3 |
| » Defeated Red Sox (14-27), 5-4 | Fenway Park (2-0) | 22-20 | Won 9 |
| » Starters: Clint Brown vs Jim Brillheart | Fourth | 9 out |
| Thursday, June 4 |
| » Defeated Red Sox (14-28), 10-2 | Fenway Park (3-0) | 23-20 | Won 10 |
| » Starters: Wes Ferrell vs Jack Russell | Fourth | 9 out |
| Friday, June 5 |
| » Lost to Red Sox (15-28), 4-3 | Fenway Park (3-1) | 23-21 | |
| » Starters: Willis Hudlin vs Ed Morris | Fourth | 9 out |
| Saturday, June 6 |
| » Defeated Yankees (24-19), 7-5 | Yankee Stadium (1-0) | 24-21 | |
| » Starters: Jake Miller vs Roy Sherid | Fourth | 9 out |
| Sunday, June 7 |
| » Lost to Yankees (25-19), 5-1 | Yankee Stadium (1-1) | 24-22 | |
| » Starters: Clint Brown vs Lefty Gomez | Fourth | 10 out |
| Monday, June 8 |
| » Defeated Yankees (25-20), 4-1 | Yankee Stadium (2-1) | 25-22 | |
| » Starters: Wes Ferrell vs Red Ruffing | Fourth | 10 out |
| Wednesday, June 10 |
| » Lost to Senators (32-17), 9-4 | Griffith Stadium (0-1) | 25-23 | |
| » Starters: Willis Hudlin vs Sam Jones | Fourth | 11 out |
| Thursday, June 11 |
| » Lost to Senators (33-17), 12-5 | Griffith Stadium (0-2) | 25-24 | Lost 2 |
| » Starters: Clint Brown vs Lloyd Brown | Fourth | 11 out |
| Friday, June 12 |
| » Lost to Senators (34-17), 7-1 | Griffith Stadium (0-3) | 25-25 | Lost 3 |
| » Starters: Wes Ferrell vs Carl Fischer | Fourth | 12 out |
| Saturday, June 13 |
| » Lost to Senators (35-17), 5-0 | Griffith Stadium (0-4) | 25-26 | Lost 4 |
| » Starters: Milt Shoffner vs Alvin Crowder | Fourth | 13½ out |
| Sunday, June 14 |
| » Defeated Athletics (38-13), 6-4 | League Park II (14-15) | 26-26 | |
| » Starters: Hank McDonald vs Clint Brown | Fourth | 12½ out |
| Monday, June 15 |
| » Lost to Athletics (39-13), 4-1 | Shibe Park (0-1) | 26-27 | |
| » Starters: Willis Hudlin vs Rube Walberg | Fourth | 13½ out |
| Wednesday, June 17 |
| » Lost to Athletics (40-13), 4-2 | Shibe Park (0-2) | 26-28 | Lost 2 |
| » Starters: Wes Ferrell vs George Earnshaw | Fourth | 14½ out |
| Friday, June 19 |
| » Defeated Senators (39-18), 9-6 | League Park II (15-15) | 27-28 | |
| » Starters: Sam Jones vs Jake Miller | Fourth | 14½ out |
| Saturday, June 20 |
| » Lost to Senators (40-18), 14-4 | League Park II (15-16) | 27-29 | |
| » Starters: Lloyd Brown vs Milt Shoffner | Fourth | 16 out |
| » Lost to Senators (41-18), 7-3 | League Park II (15-17) | 27-30 | Lost 2 |
| » Starters: Carl Fischer vs Roxie Lawson | Fourth | 16 out |
| Sunday, June 21 |
| » Defeated Senators (41-19), 3-1 | League Park II (16-17) | 28-30 | |
| » Starters: Alvin Crowder vs Wes Ferrell | Fourth | 16 out |
| Tuesday, June 23 |
| » Defeated Red Sox (22-33), 13-0 | League Park II (17-17) | 29-30 | Won 2 |
| » Starters: Jack Russell vs Clint Brown | Fourth | 14½ out |
| » Defeated Red Sox (22-34), 10-0 | League Park II (18-17) | 30-30 | Won 3 |
| » Starters: Ed Morris vs Willis Hudlin | Fourth | 14½ out |
| Wednesday, June 24 |
| » Lost to Red Sox (23-34), 7-3 | League Park II (18-18) | 30-31 | |
| » Starters: Wilcy Moore vs Mel Harder | Fourth | 14½ out |
| Thursday, June 25 |
| » Lost to Red Sox (24-34), 8-3 | League Park II (18-19) | 30-32 | Lost 2 |
| » Starters: Bob Kline vs Roxie Lawson | Fourth | 14 out |
| Saturday, June 27 |
| » Defeated Yankees (34-26), 12-5 | League Park II (19-19) | 31-32 | |
| » Starters: Hank Johnson vs Wes Ferrell | Fourth | 13½ out |
| » Defeated Yankees (34-27), 2-1 | League Park II (20-19) | 32-32 | Won 2 |
| » Starters: Herb Pennock vs Clint Brown | Fourth | 13½ out |
| Sunday, June 28 |
| » Lost to Yankees (35-27), 9-5 | League Park II (20-20) | 32-33 | |
| » Starters: Ed Wells vs Willis Hudlin | Fourth | 15 out |
| Monday, June 29 |
| » Defeated Yankees (35-28), 15-6 | League Park II (21-20) | 33-33 | |
| » Starters: Red Ruffing vs Milt Shoffner | Fourth | 13½ out |
| » Defeated Yankees (35-29), 4-2 | League Park II (22-20) | 34-33 | Won 2 |
| » Starters: Lefty Gomez vs Mel Harder | Fourth | 13½ out |
| » Major-league debuts: Red Rolfe (Yankees) |
| Tuesday, June 30 |
| » Lost to Athletics (48-19), 11-7 | League Park II (22-21) | 34-34 | |
| » Starters: George Earnshaw vs Clint Brown | Fourth | 14½ out |
| Wednesday, July 1 |
| » Lost to Athletics (49-19), 4-3 | League Park II (22-22) | 34-35 | Lost 2 |
| » Starters: Lefty Grove vs Wes Ferrell | Fourth | 15½ out |
| Thursday, July 2 |
| » Defeated Athletics (49-20), 12-4 | League Park II (23-22) | 35-35 | |
| » Starters: Rube Walberg vs Willis Hudlin | Fourth | 14½ out |
| Saturday, July 4 |
| » Defeated Tigers (26-46), 6-3 | League Park II (24-22) | 36-35 | Won 2 |
| » Starters: Earl Whitehill vs Clint Brown | Fourth | 15½ out |
| » Lost to Tigers (27-46), 8-5 | League Park II (24-23) | 36-36 | |
| » Starters: Tommy Bridges vs Mel Harder | Fourth | 15½ out |
| Sunday, July 5 |
| » Lost to Tigers (28-46), 5-4 | Tiger Stadium (4-3) | 36-37 | Lost 2 |
| » Starters: Wes Ferrell vs Vic Sorrell | Fourth | 15½ out |
| Monday, July 6 |
| » Defeated Tigers (28-47), 13-4 | League Park II (25-23) | 37-37 | |
| » Starters: Chief Hogsett vs Willis Hudlin | Fourth | 15 out |
| Wednesday, July 8 |
| » Defeated White Sox (27-47), 10-6 | Comiskey Park I (3-1) | 38-37 | Won 2 |
| » Starters: Clint Brown vs Pat Caraway | Fourth | 15½ out |
| Thursday, July 9 |
| » Lost to White Sox (28-47), 3-0 | Comiskey Park I (3-2) | 38-38 | |
| » Starters: Mel Harder vs Vic Frasier | Fourth | 15½ out |
| Saturday, July 11 |
| » Defeated White Sox (28-48), 7-4 | Comiskey Park I (4-2) | 39-38 | |
| » Starters: Willis Hudlin vs Tommy Thomas | Fourth | 15 out |
| Sunday, July 12 |
| » Defeated White Sox (28-49), 10-4 | Comiskey Park I (5-2) | 40-38 | Won 2 |
| » Starters: Wes Ferrell vs Pat Caraway | Fourth | 16 out |
| » Lost to White Sox (29-49), 7-5 | Comiskey Park I (5-3) | 40-39 | |
| » Starters: Clint Brown vs Hal McKain | Fourth | 16 out |
| Tuesday, July 14 |
| » Lost to Yankees (45-32), 19-2 | Yankee Stadium (2-2) | 40-40 | Lost 2 |
| » Starters: Milt Shoffner vs Jim Weaver | Fourth | 15½ out |
| » Defeated Yankees (45-33), 5-1 | Yankee Stadium (3-2) | 41-40 | |
| » Starters: Mel Harder vs Lefty Gomez | Fourth | 15½ out |
| Wednesday, July 15 |
| » Lost to Yankees (46-33), 5-4 | Yankee Stadium (3-3) | 41-41 | |
| » Starters: Willis Hudlin vs Hank Johnson | Fourth | 17 out |
| Thursday, July 16 |
| » Defeated Yankees (46-34), 9-8 | Yankee Stadium (4-3) | 42-41 | |
| » Starters: Clint Brown vs Red Ruffing | Fourth | 17 out |
| Friday, July 17 |
| » Defeated Yankees (46-35), 2-1 | Yankee Stadium (5-3) | 43-41 | Won 2 |
| » Starters: Wes Ferrell vs Herb Pennock | Fourth | 17 out |
| Saturday, July 18 |
| » Lost to Red Sox (30-52), 4-1 | Fenway Park (3-2) | 43-42 | |
| » Starters: Mel Harder vs Danny MacFayden | Fourth | 18½ out |
| Sunday, July 19 |
| » Lost to Red Sox (31-52), 6-5 | Braves Field (0-1) | 43-43 | Lost 2 |
| » Starters: Willis Hudlin vs Jack Russell | Fourth | 19 out |
| Monday, July 20 |
| » Defeated Red Sox (31-53), 9-2 | Fenway Park (4-2) | 44-43 | |
| » Starters: Clint Brown vs Milt Gaston | Fourth | 19 out |
| Tuesday, July 21 |
| » Lost to Red Sox (32-53), 3-2 | Fenway Park (4-3) | 44-44 | |
| » Starters: Wes Ferrell vs Hod Lisenbee | Fourth | 20 out |
| Wednesday, July 22 |
| » Lost to Athletics (66-25), 7-3 | Shibe Park (0-3) | 44-45 | Lost 2 |
| » Starters: Mel Harder vs Rube Walberg | Fourth | 21 out |
| Thursday, July 23 |
| » Lost to Athletics (67-25), 5-2 | Shibe Park (0-4) | 44-46 | Lost 3 |
| » Starters: Willis Hudlin vs George Earnshaw | Fourth | 22 out |
| Friday, July 24 |
| » Lost to Athletics (68-25), 2-1 | Shibe Park (0-5) | 44-47 | Lost 4 |
| » Starters: Clint Brown vs Roy Mahaffey | Fourth | 23 out |
| Saturday, July 25 |
| » Lost to Athletics (69-25), 6-3 | Shibe Park (0-6) | 44-48 | Lost 5 |
| » Starters: Wes Ferrell vs Lefty Grove | Fourth | 25 out |
| » Lost to Athletics (70-25), 3-2 | Shibe Park (0-7) | 44-49 | Lost 6 |
| » Starters: Sarge Connally vs Hank McDonald | Fourth | 25 out |
| Sunday, July 26 |
| » Defeated Athletics (70-26), 13-2 | League Park II (26-23) | 45-49 | |
| » Starters: Waite Hoyt vs Mel Harder | Fourth | 24 out |
| Monday, July 27 |
| » Lost to Senators (59-36), 11-7 | Griffith Stadium (0-5) | 45-50 | |
| » Starters: Willis Hudlin vs Alvin Crowder | Fourth | 25 out |
| Tuesday, July 28 |
| » Lost to Senators (60-36), 8-1 | Griffith Stadium (0-6) | 45-51 | Lost 2 |
| » Starters: Clint Brown vs Sam Jones | Fourth | 26 out |
| Wednesday, July 29 |
| » Defeated Senators (60-37), 6-0 | Griffith Stadium (1-6) | 46-51 | |
| » Starters: Wes Ferrell vs Firpo Marberry | Fourth | 26 out |
| Thursday, July 30 |
| » Lost to Senators (61-37), 6-1 | Griffith Stadium (1-7) | 46-52 | |
| » Starters: Mel Harder vs Carl Fischer | Fourth | 27 out |
| Saturday, August 1 |
| » Lost to Browns (43-53), 7-5 | Sportsman's Park III (1-3) | 46-53 | Lost 2 |
| » Starters: Clint Brown vs George Blaeholder | Fourth | 27 out |
| » Major-league debuts: Odell Hale (Indians) |
| Sunday, August 2 |
| » Defeated Browns (43-54), 9-4 | Sportsman's Park III (2-3) | 47-53 | |
| » Starters: Wes Ferrell vs Dolly Gray | Fourth | 25½ out |
| » Defeated Browns (43-55), 11-9 | Sportsman's Park III (3-3) | 48-53 | Won 2 |
| » Starters: Willis Hudlin vs Lefty Stewart | Fourth | 25½ out |
| Monday, August 3 |
| » Defeated Browns (43-56), 5-3 | Sportsman's Park III (4-3) | 49-53 | Won 3 |
| » Starters: Sarge Connally vs Wally Hebert | Fourth | 26 out |
| Wednesday, August 5 |
| » Lost to Tigers (39-66), 11-8 | Tiger Stadium (4-4) | 49-54 | |
| » Starters: Clint Brown vs Vic Sorrell | Fourth | 26½ out |
| Thursday, August 6 |
| » Defeated Tigers (39-67), 4-3 | Tiger Stadium (5-4) | 50-54 | |
| » Starters: Willis Hudlin vs Art Herring | Fourth | 25½ out |
| Saturday, August 8 |
| » Lost to Tigers (40-67), 7-1 | League Park II (26-24) | 50-55 | |
| » Starters: Earl Whitehill vs Wes Ferrell | Fourth | 25½ out |
| Sunday, August 9 |
| » Lost to Tigers (41-67), 9-8 | League Park II (26-25) | 50-56 | Lost 2 |
| » Starters: Chief Hogsett vs Sarge Connally | Fourth | 26½ out |
| Future Indian Chuck Essegian is born in Boston, MA. |
| Wednesday, August 12 |
| » Lost to Yankees (63-43), 18-1 | League Park II (26-26) | 50-57 | Lost 3 |
| » Starters: Lefty Gomez vs Willis Hudlin | Fourth | 26½ out |
| » Defeated Yankees (63-44), 17-7 | League Park II (27-26) | 51-57 | |
| » Starters: Hank Johnson vs Clint Brown | Fourth | 26½ out |
| Friday, August 14 |
| » Defeated Yankees (63-45), 13-7 | League Park II (28-26) | 52-57 | Won 2 |
| » Starters: Red Ruffing vs Mel Harder | Fourth | 26 out |
| » Defeated Yankees (63-46), 9-1 | League Park II (29-26) | 53-57 | Won 3 |
| » Starters: Gordon Rhodes vs Willis Hudlin | Fourth | 26 out |
| Saturday, August 15 |
| » Lost to Athletics (80-31), 4-3 | League Park II (29-27) | 53-58 | |
| » Starters: Lefty Grove vs Wes Ferrell | Fourth | 27 out |
| Sunday, August 16 |
| » Lost to Athletics (81-31), 6-4 | League Park II (29-28) | 53-59 | Lost 2 |
| » Starters: Roy Mahaffey vs Sarge Connally | Fourth | 28 out |
| Future Indian Don Rudolph is born in Baltimore, MD. |
| Wednesday, August 19 |
| » Defeated Senators (70-44), 10-5 | League Park II (30-28) | 54-59 | |
| » Starters: Sam Jones vs Wes Ferrell | Fourth | 27½ out |
| » Defeated Senators (70-45), 10-8 | League Park II (31-28) | 55-59 | Won 2 |
| » Starters: Bobby Burke vs Willis Hudlin | Fourth | 27½ out |
| Thursday, August 20 |
| » Defeated Senators (70-46), 10-8 | League Park II (32-28) | 56-59 | Won 3 |
| » Starters: Firpo Marberry vs Mel Harder | Fourth | 26½ out |
| Friday, August 21 |
| » Lost to Senators (71-46), 6-3 | League Park II (32-29) | 56-60 | |
| » Starters: Lloyd Brown vs Clint Brown | Fourth | 27½ out |
| Saturday, August 22 |
| » Defeated Senators (71-47), 5-2 | League Park II (33-29) | 57-60 | |
| » Starters: Carl Fischer vs Wes Ferrell | Fourth | 27½ out |
| Sunday, August 23 |
| » Defeated Red Sox (47-72), 4-3 | League Park II (34-29) | 58-60 | Won 2 |
| » Starters: Danny MacFayden vs Sarge Connally | Fourth | 27 out |
| Monday, August 24 |
| » Defeated Red Sox (47-73), 11-7 | League Park II (35-29) | 59-60 | Won 3 |
| » Starters: Milt Gaston vs Willis Hudlin | Fourth | 27 out |
| Thursday, August 27 |
| » Defeated Browns (51-72), 11-1 | League Park II (36-29) | 60-60 | Won 4 |
| » Starters: Dick Coffman vs Wes Ferrell | Fourth | 26½ out |
| Friday, August 28 |
| » Defeated Browns (51-73), 13-1 | League Park II (37-29) | 61-60 | Won 5 |
| » Starters: Dolly Gray vs Mel Harder | Fourth | 26½ out |
| Saturday, August 29 |
| » Defeated Browns (51-74), 5-3 | League Park II (38-29) | 62-60 | Won 6 |
| » Starters: George Blaeholder vs Willis Hudlin | Fourth | 26½ out |
| Sunday, August 30 |
| » Lost to Browns (52-74), 8-3 | League Park II (38-30) | 62-61 | |
| » Starters: Lefty Stewart vs Pete Appleton | Fourth | 27 out |
| » Lost to Browns (53-74), 6-3 | League Park II (38-31) | 62-62 | Lost 2 |
| » Starters: Dick Coffman vs Clint Brown | Fourth | 27 out |
| Monday, August 31 |
| » Defeated White Sox (50-77), 15-5 | Comiskey Park I (6-3) | 63-62 | |
| » Starters: Wes Ferrell vs Pat Caraway | Fourth | 27 out |
| Wednesday, September 2 |
| » Lost to White Sox (51-77), 3-2 | Comiskey Park I (6-4) | 63-63 | |
| » Starters: Mel Harder vs Red Faber | Fourth | 26½ out |
| » Tied White Sox, 4-4 | Comiskey Park I (6-4) | 63-63 | |
| » Starters: Willis Hudlin vs Tommy Thomas | Fourth | 26½ out |
| Thursday, September 3 |
| » Lost to Browns (55-76), 11-3 | Sportsman's Park III (4-4) | 63-64 | Lost 2 |
| » Starters: Clint Brown vs Dick Coffman | Fourth | 27 out |
| Saturday, September 5 |
| » Defeated Browns (55-77), 10-5 | Sportsman's Park III (5-4) | 64-64 | |
| » Starters: Wes Ferrell vs Lefty Stewart | Fourth | 27½ out |
| Sunday, September 6 |
| » Defeated Browns (55-78), 7-5 | Sportsman's Park III (6-4) | 65-64 | Won 2 |
| » Starters: Mel Harder vs Bob Cooney | Fourth | 27 out |
| » Defeated Browns (55-79), 13-2 | Sportsman's Park III (7-4) | 66-64 | Won 3 |
| » Starters: Willis Hudlin vs Dolly Gray | Fourth | 27 out |
| Monday, September 7 |
| » Defeated White Sox (52-81), 6-2 | League Park II (39-31) | 67-64 | Won 4 |
| » Starters: Tommy Thomas vs Sarge Connally | Fourth | 25 out |
| » Defeated White Sox (52-82), 5-2 | League Park II (40-31) | 68-64 | Won 5 |
| » Starters: Grant Bowler vs Clint Brown | Fourth | 25 out |
| Tuesday, September 8 |
| » Defeated White Sox (52-83), 8-7 | League Park II (41-31) | 69-64 | Won 6 |
| » Starters: Lou Garland vs Roxie Lawson | Fourth | 24½ out |
| » Defeated White Sox (52-84), 6-3 | League Park II (42-31) | 70-64 | Won 7 |
| » Starters: Pat Caraway vs Pete Appleton | Fourth | 24½ out |
| » Major-league debuts: Oral Hildebrand (Indians) |
| Wednesday, September 9 |
| Future Indian Earl Averill is born in Cleveland, OH. |
| Thursday, September 10 |
| » Lost to Senators (83-54), 5-3 | Griffith Stadium (1-8) | 70-65 | |
| » Starters: Mel Harder vs Lloyd Brown | Fourth | 25 out |
| Friday, September 11 |
| Former Indian Jack McCarthy dies in Chicago, IL at the age of 63. |
| Saturday, September 12 |
| » Defeated Senators (83-55), 7-4 | Griffith Stadium (2-8) | 71-65 | |
| » Starters: Wes Ferrell vs Sam Jones | Fourth | 24½ out |
| Sunday, September 13 |
| » Lost to Senators (84-55), 7-1 | Griffith Stadium (2-9) | 71-66 | |
| » Starters: Sarge Connally vs Alvin Crowder | Fourth | 25 out |
| Monday, September 14 |
| » Defeated Athletics (97-43), 6-2 | Shibe Park (1-7) | 72-66 | |
| » Starters: Willis Hudlin vs Rube Walberg | Fourth | 25 out |
| » Lost to Athletics (98-43), 9-7 | Shibe Park (1-8) | 72-67 | |
| » Starters: Clint Brown vs Waite Hoyt | Fourth | 25 out |
| Tuesday, September 15 |
| » Lost to Athletics (99-43), 14-3 | Shibe Park (1-9) | 72-68 | Lost 2 |
| » Starters: Mel Harder vs Eddie Rommel | Fourth | 26 out |
| Wednesday, September 16 |
| » Lost to Athletics (100-43), 7-5 | Shibe Park (1-10) | 72-69 | Lost 3 |
| » Starters: Wes Ferrell vs George Earnshaw | Fourth | 27 out |
| Thursday, September 17 |
| » Lost to Red Sox (56-86), 9-2 | Fenway Park (4-4) | 72-70 | Lost 4 |
| » Starters: Sarge Connally vs Wilcy Moore | Third | 27 out |
| » Defeated Red Sox (56-87), 2-1 | Fenway Park (5-4) | 73-70 | |
| » Starters: Pete Appleton vs Milt Gaston | Third | 27 out |
| Friday, September 18 |
| » Lost to Red Sox (57-87), 6-1 | Fenway Park (5-5) | 73-71 | |
| » Starters: Willis Hudlin vs Jack Russell | Third | 28½ out |
| » Lost to Red Sox (58-87), 6-4 | Fenway Park (5-6) | 73-72 | Lost 2 |
| » Starters: Clint Brown vs Hod Lisenbee | Third | 28½ out |
| Saturday, September 19 |
| » Lost to Red Sox (59-87), 2-1 | Fenway Park (5-7) | 73-73 | Lost 3 |
| » Starters: Oral Hildebrand vs Danny MacFayden | Fourth | 30 out |
| Sunday, September 20 |
| » Lost to Yankees (89-57), 7-1 | Yankee Stadium (5-4) | 73-74 | Lost 4 |
| » Starters: Mel Harder vs Hank Johnson | Fourth | 31 out |
| » Lost to Yankees (90-57), 10-4 | Yankee Stadium (5-5) | 73-75 | Lost 5 |
| » Starters: Sarge Connally vs Gordon Rhodes | Fourth | 31 out |
| Monday, September 21 |
| » Defeated Yankees (90-58), 5-1 | Yankee Stadium (6-5) | 74-75 | |
| » Starters: Wes Ferrell vs Red Ruffing | Third | 30½ out |
| Tuesday, September 22 |
| Future Indian Ken Aspromonte is born in Brooklyn, NY. |
| Wednesday, September 23 |
| » Lost to Tigers (61-89), 9-7 | Tiger Stadium (5-5) | 74-76 | |
| » Starters: Willis Hudlin vs Orlin Collier | Fourth | 31 out |
| » Defeated Tigers (61-90), 6-2 | Tiger Stadium (6-5) | 75-76 | |
| » Starters: Clint Brown vs Vic Sorrell | Fourth | 31 out |
| Thursday, September 24 |
| » Defeated Tigers (61-91), 6-4 | League Park II (43-31) | 76-76 | Won 2 |
| » Starters: Earl Whitehill vs Oral Hildebrand | Fourth | 31 out |
| Saturday, September 26 |
| » Defeated Tigers (61-92), 7-3 | League Park II (44-31) | 77-76 | Won 3 |
| » Starters: Tommy Bridges vs Wes Ferrell | Fourth | 31 out |
| Sunday, September 27 |
| » Defeated Tigers (61-93), 8-5 | League Park II (45-31) | 78-76 | Won 4 |
| » Starters: Art Herring vs Pete Appleton | Fourth | 30 out |
Game information provided by Retrosheet (www.retrosheet.org) |