| Saturday, January 4 |
| Future White Sox Don McMahon is born in Brooklyn, NY. |
| Thursday, April 10 |
| Future White Sox Frank Lary is born in Northport, AL. |
| Monday, April 14 |
| » Major-league debuts: Tom Oliver (Red Sox) |
| Tuesday, April 15 |
| » Major-league debuts: George Watkins (Cardinals) |
| Thursday, April 17 |
| » Defeated Indians (0-1), 8-7 | Comiskey Park I (1-0) | 1-0 | |
| » Starters: Willis Hudlin vs Tommy Thomas | Second | ½ out |
| » Major-league debuts: Johnny Riddle and Ernie Smith (White Sox) |
| Friday, April 18 |
| » Major-league debuts: Lynn Nelson and Lon Warneke (Cubs) |
| Saturday, April 19 |
| » Lost to Browns (1-2), 7-2 | Comiskey Park I (1-1) | 1-1 | |
| » Starters: Lefty Stewart vs Red Faber | Fourth | 1 out |
| » Major-league debuts: Pat Caraway (White Sox) |
| Monday, April 21 |
| » Defeated Browns (1-3), 3-2 | Comiskey Park I (2-1) | 2-1 | |
| » Starters: General Crowder vs Ted Lyons | Third | ½ out |
| Tuesday, April 22 |
| » Defeated Indians (3-3), 4-3 | League Park II (1-0) | 3-1 | Won 2 |
| » Starters: Tommy Thomas vs Wes Ferrell | Second | ½ out |
| Friday, April 25 |
| » Lost to Browns (5-3), 4-2 | Sportsman's Park III (0-1) | 3-2 | |
| » Starters: Red Faber vs Lefty Stewart | Fourth | 1½ out |
| Saturday, April 26 |
| » Lost to Browns (6-3), 12-0 | Sportsman's Park III (0-2) | 3-3 | Lost 2 |
| » Starters: Ted Lyons vs General Crowder | Fifth | 2½ out |
| Sunday, April 27 |
| » Defeated Browns (6-4), 2-1 | Sportsman's Park III (1-2) | 4-3 | |
| » Starters: Tommy Thomas vs Sam Gray | Third | 2½ out |
| Monday, April 28 |
| » Defeated Tigers (4-9), 9-7 | Tiger Stadium (1-0) | 5-3 | Won 2 |
| » Starters: Dutch Henry vs Whit Wyatt | Second | 2½ out |
| Tuesday, April 29 |
| » Defeated Tigers (4-10), 8-6 | Tiger Stadium (2-0) | 6-3 | Won 3 |
| » Starters: Red Faber vs George Uhle | Second | 2½ out |
| Wednesday, April 30 |
| » Lost to Tigers (5-10), 6-4 | Tiger Stadium (2-1) | 6-4 | |
| » Starters: Ted Blankenship vs Chief Hogsett | Third | 2½ out |
| » Major-league debuts: Irv Jeffries (White Sox) |
| Friday, May 2 |
| » Defeated Yankees (3-9), 10-1 | Yankee Stadium (1-0) | 7-4 | |
| » Starters: Ted Lyons vs Hank Johnson | Third | 2½ out |
| Saturday, May 3 |
| » Lost to Yankees (4-9), 5-3 | Yankee Stadium (1-1) | 7-5 | |
| » Starters: Hal McKain vs Waite Hoyt | Fourth | 2½ out |
| Sunday, May 4 |
| » Lost to Yankees (5-9), 7-4 | Yankee Stadium (1-2) | 7-6 | Lost 2 |
| » Starters: Tommy Thomas vs Ed Wells | Fourth | 3 out |
| Monday, May 5 |
| » Lost to Yankees (6-9), 4-1 | Yankee Stadium (1-3) | 7-7 | Lost 3 |
| » Starters: Red Faber vs Lefty Gomez | Third | 3 out |
| Tuesday, May 6 |
| » Defeated Red Sox (6-12), 4-3 | Fenway Park (1-0) | 8-7 | |
| » Starters: Ted Lyons vs Ed Morris | Third | 3 out |
| Wednesday, May 7 |
| » Lost to Red Sox (7-12), 6-4 | Fenway Park (1-1) | 8-8 | |
| » Starters: Hal McKain vs Hod Lisenbee | Third | 3 out |
| Thursday, May 8 |
| » Lost to Red Sox (8-12), 3-1 | Fenway Park (1-2) | 8-9 | Lost 2 |
| » Starters: Tommy Thomas vs Jack Russell | Fourth | 4 out |
| Friday, May 9 |
| » Lost to Senators (14-7), 14-3 | Griffith Stadium (0-1) | 8-10 | Lost 3 |
| » Starters: Dutch Henry vs Lloyd Brown | Fourth | 5 out |
| Saturday, May 10 |
| » Lost to Senators (15-7), 5-1 | Griffith Stadium (0-2) | 8-11 | Lost 4 |
| » Starters: Red Faber vs Ad Liska | Fifth | 6 out |
| Sunday, May 11 |
| » Defeated Senators (15-8), 5-3 | Griffith Stadium (1-2) | 9-11 | |
| » Starters: Ted Lyons vs Bump Hadley | Fifth | 5 out |
| Monday, May 12 |
| » Lost to Senators (16-8), 13-2 | Griffith Stadium (1-3) | 9-12 | |
| » Starters: Tommy Thomas vs Bobby Burke | Sixth | 6 out |
| Tuesday, May 13 |
| » Lost to Athletics (17-7), 14-7 | Shibe Park (0-1) | 9-13 | Lost 2 |
| » Starters: Hal McKain vs Bill Shores | Sixth | 7 out |
| Saturday, May 17 |
| » Defeated Indians (14-11), 4-1 | Comiskey Park I (3-1) | 10-13 | |
| » Starters: Wes Ferrell vs Ted Lyons | Fifth | 6½ out |
| » Defeated Indians (14-12), 6-2 | Comiskey Park I (4-1) | 11-13 | Won 2 |
| » Starters: Clint Brown vs Pat Caraway | Fifth | 6½ out |
| Sunday, May 18 |
| » Lost to Indians (15-12), 7-4 | Comiskey Park I (4-2) | 11-14 | |
| » Starters: Mel Harder vs Dutch Henry | Fifth | 6½ out |
| Tuesday, May 20 |
| » Lost to Indians (16-12), 7-3 | Comiskey Park I (4-3) | 11-15 | Lost 2 |
| » Starters: Willis Hudlin vs Red Faber | Sixth | 7½ out |
| » Lost to Indians (17-12), 7-5 | Comiskey Park I (4-4) | 11-16 | Lost 3 |
| » Starters: Ken Holloway vs Ed Walsh | Sixth | 7½ out |
| Wednesday, May 21 |
| » Defeated Tigers (12-21), 9-3 | Comiskey Park I (5-4) | 12-16 | |
| » Starters: Earl Whitehill vs Ted Lyons | Fifth | 8 out |
| Thursday, May 22 |
| » Lost to Tigers (13-21), 6-1 | Comiskey Park I (5-5) | 12-17 | |
| » Starters: George Uhle vs Dutch Henry | Sixth | 9½ out |
| Saturday, May 24 |
| » Defeated Tigers (13-22), 8-7 | Comiskey Park I (6-5) | 13-17 | |
| » Starters: Chief Hogsett vs Tommy Thomas | Fifth | 9 out |
| Sunday, May 25 |
| » Defeated Indians (18-16), 9-1 | League Park II (2-0) | 14-17 | Won 2 |
| » Starters: Ted Lyons vs Jake Miller | Fifth | 9 out |
| Monday, May 26 |
| » Lost to Indians (19-16), 7-3 | League Park II (2-1) | 14-18 | |
| » Starters: Red Faber vs Wes Ferrell | Fifth | 10½ out |
| » Lost to Indians (20-16), 5-2 | League Park II (2-2) | 14-19 | Lost 2 |
| » Starters: Pat Caraway vs Clint Brown | Fifth | 10½ out |
| Tuesday, May 27 |
| » Lost to Indians (21-16), 3-2 | League Park II (2-3) | 14-20 | Lost 3 |
| » Starters: Dutch Henry vs Mel Harder | Sixth | 12 out |
| » Lost to Indians (22-16), 9-8 | League Park II (2-4) | 14-21 | Lost 4 |
| » Starters: Hal McKain vs Pete Appleton | Sixth | 12 out |
| Friday, May 30 |
| » Defeated Browns (15-23), 7-4 | Sportsman's Park III (2-2) | 15-21 | |
| » Starters: Tommy Thomas vs Sam Gray | Seventh | 10½ out |
| » Lost to Browns (16-23), 4-3 | Sportsman's Park III (2-3) | 15-22 | |
| » Starters: Ted Lyons vs Rip Collins | Seventh | 10½ out |
| Saturday, May 31 |
| » Lost to Browns (17-23), 3-2 | Sportsman's Park III (2-4) | 15-23 | Lost 2 |
| » Starters: Red Faber vs General Crowder | Sixth | 10½ out |
| Sunday, June 1 |
| » Defeated Browns (17-24), 8-5 | Sportsman's Park III (3-4) | 16-23 | |
| » Starters: Ed Walsh vs Lefty Stewart | Seventh | 10½ out |
| Tuesday, June 3 |
| » Lost to Yankees (23-18), 13-7 | Comiskey Park I (6-6) | 16-24 | |
| » Starters: George Pipgras vs Ted Lyons | Seventh | 11½ out |
| Wednesday, June 4 |
| » Defeated Yankees (23-19), 8-7 | Comiskey Park I (7-6) | 17-24 | |
| » Starters: Red Ruffing vs Pat Caraway | Fifth | 11½ out |
| Saturday, June 7 |
| » Defeated Athletics (31-16), 6-5 | Comiskey Park I (8-6) | 18-24 | Won 2 |
| » Starters: Lefty Grove vs Tommy Thomas | Fifth | 10½ out |
| Sunday, June 8 |
| » Lost to Athletics (32-16), 6-3 | Comiskey Park I (8-7) | 18-25 | |
| » Starters: George Earnshaw vs Ted Lyons | Sixth | 11½ out |
| Monday, June 9 |
| » Lost to Athletics (33-16), 3-2 | Comiskey Park I (8-8) | 18-26 | Lost 2 |
| » Starters: Rube Walberg vs Bob Weiland | Sixth | 12½ out |
| Tuesday, June 10 |
| » Defeated Athletics (33-17), 7-6 | Comiskey Park I (9-8) | 19-26 | |
| » Starters: Roy Mahaffey vs Pat Caraway | Fifth | 11½ out |
| Wednesday, June 11 |
| » Lost to Senators (30-18), 2-1 | Comiskey Park I (9-9) | 19-27 | |
| » Starters: Bump Hadley vs Dutch Henry | Sixth | 11½ out |
| Thursday, June 12 |
| » Defeated Senators (30-19), 10-6 | Comiskey Park I (10-9) | 20-27 | |
| » Starters: Bobby Burke vs Ted Lyons | Fifth | 10½ out |
| Friday, June 13 |
| » Lost to Senators (31-19), 6-2 | Comiskey Park I (10-10) | 20-28 | |
| » Starters: Ad Liska vs Bob Weiland | Fifth | 10½ out |
| Saturday, June 14 |
| » Lost to Red Sox (17-35), 8-4 | Comiskey Park I (10-11) | 20-29 | Lost 2 |
| » Starters: Danny MacFayden vs Red Faber | Seventh | 10½ out |
| Monday, June 16 |
| » Lost to Red Sox (18-35), 6-3 | Comiskey Park I (10-12) | 20-30 | Lost 3 |
| » Starters: Jack Russell vs Ted Lyons | Sixth | 11 out |
| Tuesday, June 17 |
| » Lost to Red Sox (19-35), 8-5 | Comiskey Park I (10-13) | 20-31 | Lost 4 |
| » Starters: Milt Gaston vs Ed Walsh | Sixth | 11½ out |
| Thursday, June 19 |
| » Lost to Senators (33-22), 3-1 | Griffith Stadium (1-4) | 20-32 | Lost 5 |
| » Starters: Dutch Henry vs General Crowder | Seventh | 13 out |
| Friday, June 20 |
| » Defeated Senators (33-23), 2-1 | Griffith Stadium (2-4) | 21-32 | |
| » Starters: Ted Lyons vs Bump Hadley | Seventh | 13 out |
| Saturday, June 21 |
| » Defeated Senators (33-24), 7-2 | Griffith Stadium (3-4) | 22-32 | Won 2 |
| » Starters: Garland Braxton vs Lloyd Brown | Seventh | 13 out |
| Sunday, June 22 |
| » Lost to Senators (34-24), 10-3 | Griffith Stadium (3-5) | 22-33 | |
| » Starters: Bob Weiland vs Ad Liska | Seventh | 13 out |
| Monday, June 23 |
| » Lost to Athletics (39-23), 2-1 | Shibe Park (0-2) | 22-34 | Lost 2 |
| » Starters: Red Faber vs Lefty Grove | Sixth | 15 out |
| » Lost to Athletics (40-23), 17-9 | Shibe Park (0-3) | 22-35 | Lost 3 |
| » Starters: Dutch Henry vs Roy Mahaffey | Sixth | 15 out |
| Wednesday, June 25 |
| » Lost to Athletics (41-23), 8-1 | Shibe Park (0-4) | 22-36 | Lost 4 |
| » Starters: Ted Lyons vs George Earnshaw | Seventh | 15 out |
| » Defeated Athletics (41-24), 7-2 | Shibe Park (1-4) | 23-36 | |
| » Starters: Pat Caraway vs Rube Walberg | Seventh | 15 out |
| Thursday, June 26 |
| » Lost to Red Sox (24-40), 9-7 | Fenway Park (1-3) | 23-37 | |
| » Starters: Tommy Thomas vs Milt Gaston | Seventh | 16 out |
| Saturday, June 28 |
| » Lost to Red Sox (25-40), 4-2 | Fenway Park (1-4) | 23-38 | Lost 2 |
| » Starters: Dutch Henry vs Danny MacFayden | Eighth | 17 out |
| Sunday, June 29 |
| » Lost to Red Sox (26-40), 10-6 | Braves Field (0-1) | 23-39 | Lost 3 |
| » Starters: Red Faber vs Hod Lisenbee | Sixth | 17½ out |
| » Defeated Red Sox (26-41), 2-1 | Braves Field (1-1) | 24-39 | |
| » Starters: Ted Lyons vs Jack Russell | Sixth | 17½ out |
| Monday, June 30 |
| » Lost to Yankees (42-25), 15-4 | Yankee Stadium (1-4) | 24-40 | |
| » Starters: Garland Braxton vs George Pipgras | Sixth | 18½ out |
| Wednesday, July 2 |
| » Lost to Yankees (43-25), 5-1 | Yankee Stadium (1-5) | 24-41 | Lost 2 |
| » Starters: Dutch Henry vs Roy Sherid | Eighth | 19 out |
| » Defeated Yankees (43-26), 15-4 | Yankee Stadium (2-5) | 25-41 | |
| » Starters: Hal McKain vs Red Ruffing | Eighth | 19 out |
| Thursday, July 3 |
| Future White Sox Al Pilarcik is born in Whiting, IN. |
| Friday, July 4 |
| » Lost to Browns (30-43), 11-3 | Comiskey Park I (10-14) | 25-42 | |
| » Starters: Rip Collins vs Ted Lyons | Eighth | 19½ out |
| » Defeated Browns (30-44), 6-4 | Comiskey Park I (11-14) | 26-42 | |
| » Starters: Lefty Stewart vs Tommy Thomas | Eighth | 19½ out |
| Saturday, July 5 |
| » Defeated Browns (30-45), 8-1 | Comiskey Park I (12-14) | 27-42 | Won 2 |
| » Starters: Dick Coffman vs Red Faber | Eighth | 19½ out |
| Sunday, July 6 |
| » Lost to Tigers (34-43), 5-2 | Comiskey Park I (12-15) | 27-43 | |
| » Starters: Waite Hoyt vs Garland Braxton | Eighth | 20½ out |
| Monday, July 7 |
| » Lost to Tigers (35-43), 3-2 | Comiskey Park I (12-16) | 27-44 | Lost 2 |
| » Starters: Earl Whitehill vs Dutch Henry | Seventh | 20 out |
| » Defeated Tigers (35-44), 9-5 | Comiskey Park I (13-16) | 28-44 | |
| » Starters: Art Herring vs Pat Caraway | Seventh | 20 out |
| Tuesday, July 8 |
| » Defeated Tigers (35-45), 3-2 | Comiskey Park I (14-16) | 29-44 | Won 2 |
| » Starters: Vic Sorrell vs Ted Lyons | Sixth | 20 out |
| Wednesday, July 9 |
| » Lost to Tigers (36-45), 6-1 | Comiskey Park I (14-17) | 29-45 | |
| » Starters: George Uhle vs Tommy Thomas | Sixth | 20½ out |
| Thursday, July 10 |
| » Lost to Browns (32-48), 7-6 | Sportsman's Park III (3-5) | 29-46 | Lost 2 |
| » Starters: Red Faber vs Lefty Stewart | Seventh | 21½ out |
| Friday, July 11 |
| » Defeated Browns (32-49), 5-3 | Sportsman's Park III (4-5) | 30-46 | |
| » Starters: Pat Caraway vs George Blaeholder | Sixth | 21 out |
| Saturday, July 12 |
| » Defeated Yankees (45-34), 11-6 | Comiskey Park I (15-17) | 31-46 | Won 2 |
| » Starters: George Pipgras vs Ted Lyons | Sixth | 21 out |
| » Lost to Yankees (46-34), 11-7 | Comiskey Park I (15-18) | 31-47 | |
| » Starters: Ed Wells vs Tommy Thomas | Sixth | 21 out |
| Sunday, July 13 |
| » Lost to Yankees (47-34), 7-5 | Comiskey Park I (15-19) | 31-48 | Lost 2 |
| » Starters: Roy Sherid vs Dutch Henry | Sixth | 22 out |
| Monday, July 14 |
| » Defeated Yankees (47-35), 10-9 | Comiskey Park I (16-19) | 32-48 | |
| » Starters: Hank Johnson vs Red Faber | Sixth | 22½ out |
| » Lost to Yankees (48-35), 7-2 | Comiskey Park I (16-20) | 32-49 | |
| » Starters: Red Ruffing vs Garland Braxton | Sixth | 22½ out |
| Tuesday, July 15 |
| » Lost to Yankees (49-35), 9-5 | Comiskey Park I (16-21) | 32-50 | Lost 2 |
| » Starters: Herb Pennock vs Pat Caraway | Sixth | 23½ out |
| Wednesday, July 16 |
| » Lost to Athletics (59-29), 14-7 | Comiskey Park I (16-22) | 32-51 | Lost 3 |
| » Starters: Lefty Grove vs Ted Lyons | Sixth | 24½ out |
| Thursday, July 17 |
| » Lost to Athletics (60-29), 12-8 | Comiskey Park I (16-23) | 32-52 | Lost 4 |
| » Starters: Roy Mahaffey vs Tommy Thomas | Sixth | 25½ out |
| Friday, July 18 |
| » Lost to Athletics (61-29), 15-1 | Comiskey Park I (16-24) | 32-53 | Lost 5 |
| » Starters: George Earnshaw vs Garland Braxton | Sixth | 26½ out |
| Saturday, July 19 |
| » Defeated Athletics (61-30), 10-9 | Comiskey Park I (17-24) | 33-53 | |
| » Starters: Roy Mahaffey vs Red Faber | Sixth | 25½ out |
| Sunday, July 20 |
| » Defeated Red Sox (32-56), 16-4 | Comiskey Park I (18-24) | 34-53 | Won 2 |
| » Starters: Jack Russell vs Ted Lyons | Sixth | 25 out |
| » Defeated Red Sox (32-57), 5-4 | Comiskey Park I (19-24) | 35-53 | Won 3 |
| » Starters: George Smith vs Pat Caraway | Sixth | 25 out |
| Monday, July 21 |
| » Lost to Red Sox (33-57), 3-1 | Comiskey Park I (19-25) | 35-54 | |
| » Starters: Hod Lisenbee vs Tommy Thomas | Sixth | 25 out |
| Tuesday, July 22 |
| » Lost to Red Sox (34-57), 4-3 | Comiskey Park I (19-26) | 35-55 | Lost 2 |
| » Starters: Milt Gaston vs Dutch Henry | Seventh | 25 out |
| Wednesday, July 23 |
| » Defeated Red Sox (34-58), 5-3 | Comiskey Park I (20-26) | 36-55 | |
| » Starters: Danny MacFayden vs Red Faber | Sixth | 25 out |
| Thursday, July 24 |
| » Defeated Senators (58-36), 10-4 | Comiskey Park I (21-26) | 37-55 | Won 2 |
| » Starters: Ad Liska vs Ted Lyons | Sixth | 25 out |
| Friday, July 25 |
| » Defeated Senators (58-37), 6-5 | Comiskey Park I (22-26) | 38-55 | Won 3 |
| » Starters: General Crowder vs Tommy Thomas | Sixth | 25 out |
| Saturday, July 26 |
| » Defeated Senators (58-38), 4-1 | Comiskey Park I (23-26) | 39-55 | Won 4 |
| » Starters: Sad Sam Jones vs Pat Caraway | Sixth | 25 out |
| Sunday, July 27 |
| » Lost to Senators (59-38), 10-1 | Comiskey Park I (23-27) | 39-56 | |
| » Starters: Firpo Marberry vs Dutch Henry | Sixth | 25 out |
| Monday, July 28 |
| » Defeated Browns (40-59), 6-5 | Sportsman's Park III (5-5) | 40-56 | |
| » Starters: Ted Lyons vs Rip Collins | Sixth | 25 out |
| Future White Sox Ted Lepcio is born in Utica, NY. |
| Tuesday, July 29 |
| » Defeated Browns (40-60), 6-2 | Sportsman's Park III (6-5) | 41-56 | Won 2 |
| » Starters: Tommy Thomas vs Rollie Stiles | Sixth | 24 out |
| Wednesday, July 30 |
| » Lost to Browns (41-60), 3-2 | Comiskey Park I (23-28) | 41-57 | |
| » Starters: Lefty Stewart vs Red Faber | Sixth | 25½ out |
| » Lost to Browns (42-60), 6-1 | Comiskey Park I (23-29) | 41-58 | Lost 2 |
| » Starters: George Blaeholder vs Pat Caraway | Sixth | 25½ out |
| Thursday, July 31 |
| » Defeated Browns (42-61), 10-2 | Comiskey Park I (24-29) | 42-58 | |
| » Starters: Sam Gray vs Garland Braxton | Sixth | 25 out |
| » Defeated Browns (42-62), 1-0 | Comiskey Park I (25-29) | 43-58 | Won 2 |
| » Starters: Dick Coffman vs Ted Lyons | Sixth | 25 out |
| Friday, August 1 |
| » Lost to Tigers (49-56), 12-4 | Tiger Stadium (2-2) | 43-59 | |
| » Starters: Dutch Henry vs Earl Whitehill | Sixth | 25½ out |
| Saturday, August 2 |
| » Lost to Tigers (50-56), 13-2 | Tiger Stadium (2-3) | 43-60 | Lost 2 |
| » Starters: Tommy Thomas vs George Uhle | Sixth | 27 out |
| Sunday, August 3 |
| » Lost to Tigers (51-56), 4-3 | Tiger Stadium (2-4) | 43-61 | Lost 3 |
| » Starters: Pat Caraway vs Waite Hoyt | Sixth | 27 out |
| Monday, August 4 |
| » Lost to Tigers (52-56), 7-3 | Tiger Stadium (2-5) | 43-62 | Lost 4 |
| » Starters: Ted Lyons vs Vic Sorrell | Sixth | 28 out |
| Wednesday, August 6 |
| » Lost to Browns (44-65), 5-0 | Comiskey Park I (25-30) | 43-63 | Lost 5 |
| » Starters: Dick Coffman vs Tommy Thomas | Sixth | 27 out |
| » Defeated Browns (44-66), 5-2 | Comiskey Park I (26-30) | 44-63 | |
| » Starters: Rip Collins vs Red Faber | Sixth | 27 out |
| Friday, August 8 |
| » Lost to Athletics (74-37), 5-1 | Shibe Park (1-5) | 44-64 | |
| » Starters: Garland Braxton vs Lefty Grove | Sixth | 29½ out |
| » Lost to Athletics (75-37), 4-1 | Shibe Park (1-6) | 44-65 | Lost 2 |
| » Starters: Ted Lyons vs Bill Shores | Sixth | 29½ out |
| Saturday, August 9 |
| » Lost to Athletics (76-37), 9-2 | Shibe Park (1-7) | 44-66 | Lost 3 |
| » Starters: Ed Walsh vs Eddie Rommel | Sixth | 31½ out |
| » Lost to Athletics (77-37), 3-0 | Shibe Park (1-8) | 44-67 | Lost 4 |
| » Starters: Pat Caraway vs George Earnshaw | Sixth | 31½ out |
| Monday, August 11 |
| » Defeated Athletics (77-38), 8-3 | Shibe Park (2-8) | 45-67 | |
| » Starters: Red Faber vs Rube Walberg | Sixth | 30½ out |
| Tuesday, August 12 |
| » Lost to Senators (68-45), 5-4 | Griffith Stadium (3-6) | 45-68 | |
| » Starters: Ted Lyons vs Lloyd Brown | Sixth | 32 out |
| Wednesday, August 13 |
| » Lost to Senators (69-45), 7-4 | Griffith Stadium (3-7) | 45-69 | Lost 2 |
| » Starters: Garland Braxton vs Bump Hadley | Seventh | 33 out |
| Thursday, August 14 |
| » Lost to Senators (70-45), 5-4 | Griffith Stadium (3-8) | 45-70 | Lost 3 |
| » Starters: Pat Caraway vs Carl Fischer | Seventh | 33 out |
| Sunday, August 17 |
| » Lost to Yankees (70-48), 8-7 | Yankee Stadium (2-6) | 45-71 | Lost 4 |
| » Starters: Ted Lyons vs George Pipgras | Sixth | 33½ out |
| » Defeated Yankees (70-49), 6-1 | Yankee Stadium (3-6) | 46-71 | |
| » Starters: Red Faber vs Lou McEvoy | Sixth | 33½ out |
| Monday, August 18 |
| » Lost to Yankees (71-49), 11-4 | Yankee Stadium (3-7) | 46-72 | |
| » Starters: Garland Braxton vs Herb Pennock | Sixth | 34½ out |
| Tuesday, August 19 |
| » Lost to Yankees (72-49), 3-0 | Yankee Stadium (3-8) | 46-73 | Lost 2 |
| » Starters: Pat Caraway vs Red Ruffing | Seventh | 34½ out |
| Thursday, August 21 |
| » Lost to Red Sox (42-79), 4-2 | Fenway Park (1-5) | 46-74 | Lost 3 |
| » Starters: Tommy Thomas vs Hod Lisenbee | Seventh | 36 out |
| Friday, August 22 |
| » Defeated Red Sox (42-80), 6-4 | Fenway Park (2-5) | 47-74 | |
| » Starters: Ted Lyons vs Danny MacFayden | Seventh | 35 out |
| Sunday, August 24 |
| » Lost to Red Sox (43-80), 2-0 | Braves Field (1-2) | 47-75 | |
| » Starters: Red Faber vs Milt Gaston | Seventh | 35 out |
| » Defeated Red Sox (43-81), 5-4 | Braves Field (2-2) | 48-75 | |
| » Starters: Pat Caraway vs Ed Durham | Seventh | 35 out |
| Wednesday, August 27 |
| » Defeated Indians (66-61), 14-5 | League Park II (3-4) | 49-75 | Won 2 |
| » Starters: Tommy Thomas vs Willis Hudlin | Sixth | 34 out |
| » Defeated Indians (66-62), 5-4 | League Park II (4-4) | 50-75 | Won 3 |
| » Starters: Ted Lyons vs Milt Shoffner | Sixth | 34 out |
| Thursday, August 28 |
| » Lost to Indians (67-62), 10-5 | League Park II (4-5) | 50-76 | |
| » Starters: Dutch Henry vs Wes Ferrell | Seventh | 34 out |
| Friday, August 29 |
| » Defeated Indians (67-63), 3-0 | League Park II (5-5) | 51-76 | |
| » Starters: Pat Caraway vs Clint Brown | Seventh | 33½ out |
| Saturday, August 30 |
| » Lost to Indians (68-63), 7-6 | League Park II (5-6) | 51-77 | |
| » Starters: Red Faber vs Willis Hudlin | Seventh | 34½ out |
| Sunday, August 31 |
| » Lost to Tigers (62-70), 4-1 | Comiskey Park I (26-31) | 51-78 | Lost 2 |
| » Starters: Tommy Bridges vs Jim Moore | Seventh | 35½ out |
| » Major-league debuts: Jimmy Moore (White Sox) |
| Monday, September 1 |
| » Lost to Tigers (63-70), 6-5 | Comiskey Park I (26-32) | 51-79 | Lost 3 |
| » Starters: George Uhle vs Ted Lyons | Seventh | 36½ out |
| » Lost to Tigers (64-70), 4-2 | Comiskey Park I (26-33) | 51-80 | Lost 4 |
| » Starters: Earl Whitehill vs Tommy Thomas | Seventh | 36½ out |
| Future White Sox Dean Stone is born in Moline, IL. |
| Thursday, September 4 |
| » Lost to Indians (73-63), 3-2 | Comiskey Park I (26-34) | 51-81 | Lost 5 |
| » Starters: Willis Hudlin vs Pat Caraway | Seventh | 38 out |
| Friday, September 5 |
| » Lost to Indians (74-63), 6-1 | Comiskey Park I (26-35) | 51-82 | Lost 6 |
| » Starters: Pete Appleton vs Red Faber | Seventh | 39 out |
| Saturday, September 6 |
| » Defeated Indians (74-64), 2-1 | Comiskey Park I (27-35) | 52-82 | |
| » Starters: Wes Ferrell vs Ted Lyons | Seventh | 39½ out |
| » Lost to Indians (75-64), 4-2 | Comiskey Park I (27-36) | 52-83 | |
| » Starters: Mel Harder vs Tommy Thomas | Seventh | 39½ out |
| Sunday, September 7 |
| » Defeated Indians (75-65), 5-2 | Comiskey Park I (28-36) | 53-83 | |
| » Starters: Clint Brown vs Jim Moore | Seventh | 38½ out |
| Tuesday, September 9 |
| » Defeated Red Sox (45-91), 10-1 | Comiskey Park I (29-36) | 54-83 | Won 2 |
| » Starters: Jack Russell vs Pat Caraway | Sixth | 38½ out |
| Wednesday, September 10 |
| » Lost to Red Sox (46-91), 6-2 | Comiskey Park I (29-37) | 54-84 | |
| » Starters: Danny MacFayden vs Red Faber | Seventh | 38½ out |
| Thursday, September 11 |
| » Defeated Red Sox (46-92), 4-3 | Comiskey Park I (30-37) | 55-84 | |
| » Starters: Hod Lisenbee vs Ted Lyons | Seventh | 38 out |
| Friday, September 12 |
| » Lost to Senators (87-53), 8-7 | Comiskey Park I (30-38) | 55-85 | |
| » Starters: Firpo Marberry vs Tommy Thomas | Seventh | 38½ out |
| » Major-league debuts: Bruce Campbell (White Sox) |
| Saturday, September 13 |
| » Lost to Senators (88-53), 6-4 | Comiskey Park I (30-39) | 55-86 | Lost 2 |
| » Starters: Bump Hadley vs Pat Caraway | Seventh | 39½ out |
| Sunday, September 14 |
| » Defeated Senators (88-54), 2-1 | Comiskey Park I (31-39) | 56-86 | |
| » Starters: General Crowder vs Jim Moore | Seventh | 39½ out |
| Monday, September 15 |
| » Lost to Senators (89-54), 14-9 | Comiskey Park I (31-40) | 56-87 | |
| » Starters: Sad Sam Jones vs Ted Lyons | Seventh | 40 out |
| » Major-league debuts: Biggs Wehde (White Sox) |
| Tuesday, September 16 |
| » Lost to Athletics (97-47), 6-4 | Comiskey Park I (31-41) | 56-88 | Lost 2 |
| » Starters: Lefty Grove vs Tommy Thomas | Seventh | 42 out |
| » Lost to Athletics (98-47), 10-2 | Comiskey Park I (31-42) | 56-89 | Lost 3 |
| » Starters: Bill Shores vs Garland Braxton | Seventh | 42 out |
| Wednesday, September 17 |
| » Defeated Athletics (98-48), 4-2 | Comiskey Park I (32-42) | 57-89 | |
| » Starters: Eddie Rommel vs Red Faber | Seventh | 41 out |
| Thursday, September 18 |
| » Lost to Athletics (99-48), 14-10 | Comiskey Park I (32-43) | 57-90 | |
| » Starters: George Earnshaw vs Jim Moore | Seventh | 42 out |
| Friday, September 19 |
| » Lost to Yankees (84-64), 18-9 | Comiskey Park I (32-44) | 57-91 | Lost 2 |
| » Starters: Roy Sherid vs Ted Lyons | Seventh | 42½ out |
| Saturday, September 20 |
| » Defeated Yankees (84-65), 10-7 | Comiskey Park I (33-44) | 58-91 | |
| » Starters: Frank Barnes vs Tommy Thomas | Seventh | 41½ out |
| Sunday, September 21 |
| » Defeated Yankees (84-66), 15-7 | Comiskey Park I (34-44) | 59-91 | Won 2 |
| » Starters: Sam Gibson vs Pat Caraway | Seventh | 41 out |
| Friday, September 26 |
| » Defeated Tigers (74-77), 3-1 | Tiger Stadium (3-5) | 60-91 | Won 3 |
| » Starters: Ted Lyons vs Waite Hoyt | Seventh | 41½ out |
| Saturday, September 27 |
| » Lost to Tigers (75-77), 6-5 | Tiger Stadium (3-6) | 60-92 | |
| » Starters: Tommy Thomas vs Vic Sorrell | Seventh | 41 out |
| » Defeated Tigers (75-78), 10-5 | Tiger Stadium (4-6) | 61-92 | |
| » Starters: Red Faber vs Mark Koenig | Seventh | 41 out |
| Sunday, September 28 |
| » Defeated Tigers (75-79), 10-7 | Tiger Stadium (5-6) | 62-92 | Won 2 |
| » Starters: Jim Moore vs Earl Whitehill | Seventh | 40 out |
| Wednesday, November 19 |
| Former White Sox John Russell dies in Ely, NV at the age of 37. |
| Thursday, December 18 |
| Future White Sox Bill Skowron is born in Chicago, IL. |
Game information provided by Retrosheet (www.retrosheet.org) |