| Saturday, January 4 |
| Future Tiger Don McMahon is born in Brooklyn, NY. |
| Thursday, January 30 |
| Future Tiger Sandy Amoros is born in Havana, Cuba. |
| Tuesday, February 18 |
| Future Tiger Frank House is born in Bessemer, AL. |
| Friday, February 28 |
| Future Tiger Ron Samford is born in Dallas, TX. |
| Thursday, April 10 |
| Future Tiger Frank Lary is born in Northport, AL. |
| Monday, April 14 |
| » Major-league debuts: Tom Oliver (Red Sox) |
| Former Tiger Frank Kitson dies in Allegan, MI at the age of 61. |
| Tuesday, April 15 |
| » Defeated Browns (0-1), 6-3 | Tiger Stadium (1-0) | 1-0 | |
| » Starters: Sam Gray vs George Uhle | First | -- |
| » Major-league debuts: Ted Gullic (Browns) |
| Thursday, April 17 |
| » Defeated Browns (0-2), 6-1 | Tiger Stadium (2-0) | 2-0 | Won 2 |
| » Starters: General Crowder vs Earl Whitehill | First | -- |
| Friday, April 18 |
| » Lost to Indians (1-1), 7-1 | Tiger Stadium (2-1) | 2-1 | |
| » Starters: Wes Ferrell vs Ownie Carroll | Second | 1 out |
| Saturday, April 19 |
| » Defeated Indians (1-2), 6-4 | Tiger Stadium (3-1) | 3-1 | |
| » Starters: Jake Miller vs Chief Hogsett | Second | 1 out |
| » Major-league debuts: Bob Seeds (Indians) |
| Sunday, April 20 |
| » Lost to Indians (2-2), 2-0 | Tiger Stadium (3-2) | 3-2 | |
| » Starters: Willis Hudlin vs George Uhle | Second | 1 out |
| Monday, April 21 |
| » Lost to Indians (3-2), 6-1 | Tiger Stadium (3-3) | 3-3 | Lost 2 |
| » Starters: Clint Brown vs Earl Whitehill | Fifth | 1 out |
| Tuesday, April 22 |
| » Lost to Browns (2-3), 5-4 | Sportsman's Park III (0-1) | 3-4 | Lost 3 |
| » Starters: Vic Sorrell vs Sam Gray | Fifth | 2 out |
| Wednesday, April 23 |
| » Lost to Browns (3-3), 5-1 | Sportsman's Park III (0-2) | 3-5 | Lost 4 |
| » Starters: Art Herring vs Dick Coffman | Sixth | 2½ out |
| Thursday, April 24 |
| » Lost to Browns (4-3), 12-4 | Sportsman's Park III (0-3) | 3-6 | Lost 5 |
| » Starters: Chief Hogsett vs Herm Holshouser | Seventh | 3 out |
| Friday, April 25 |
| » Lost to Indians (4-3), 5-4 | League Park II (0-1) | 3-7 | Lost 6 |
| » Starters: George Uhle vs Willis Hudlin | Seventh | 4 out |
| Saturday, April 26 |
| » Lost to Indians (5-3), 11-4 | League Park II (0-2) | 3-8 | Lost 7 |
| » Starters: Earl Whitehill vs Clint Brown | Eighth | 5 out |
| Sunday, April 27 |
| » Defeated Indians (5-4), 7-1 | League Park II (1-2) | 4-8 | |
| » Starters: Vic Sorrell vs Wes Ferrell | Seventh | 5 out |
| Monday, April 28 |
| » Lost to White Sox (5-3), 9-7 | Tiger Stadium (3-4) | 4-9 | |
| » Starters: Dutch Henry vs Whit Wyatt | Seventh | 6 out |
| Tuesday, April 29 |
| » Lost to White Sox (6-3), 8-6 | Tiger Stadium (3-5) | 4-10 | Lost 2 |
| » Starters: Red Faber vs George Uhle | Seventh | 7 out |
| Wednesday, April 30 |
| » Defeated White Sox (6-4), 6-4 | Tiger Stadium (4-5) | 5-10 | |
| » Starters: Ted Blankenship vs Chief Hogsett | Seventh | 6 out |
| » Major-league debuts: Irv Jeffries (White Sox) |
| Thursday, May 1 |
| » Lost to Athletics (7-5), 19-2 | Shibe Park (0-1) | 5-11 | |
| » Starters: Vic Sorrell vs Lefty Grove | Seventh | 6½ out |
| » Major-league debuts: Charlie Perkins (Athletics) |
| Friday, May 2 |
| » Lost to Athletics (8-5), 9-4 | Shibe Park (0-2) | 5-12 | Lost 2 |
| » Starters: Earl Whitehill vs Rube Walberg | Seventh | 7½ out |
| Saturday, May 3 |
| » Lost to Athletics (9-5), 6-5 | Shibe Park (0-3) | 5-13 | Lost 3 |
| » Starters: Ownie Carroll vs George Earnshaw | Eighth | 7½ out |
| Sunday, May 4 |
| » Lost to Athletics (10-5), 7-1 | Tiger Stadium (4-6) | 5-14 | Lost 4 |
| » Starters: Bill Shores vs George Uhle | Eighth | 8 out |
| Monday, May 5 |
| » Defeated Senators (11-6), 3-1 | Griffith Stadium (1-0) | 6-14 | |
| » Starters: Chief Hogsett vs Lloyd Brown | Seventh | 7 out |
| Tuesday, May 6 |
| » Lost to Senators (12-6), 5-4 | Griffith Stadium (1-1) | 6-15 | |
| » Starters: Vic Sorrell vs Firpo Marberry | Seventh | 8 out |
| Wednesday, May 7 |
| » Defeated Senators (12-7), 3-1 | Griffith Stadium (2-1) | 7-15 | |
| » Starters: Earl Whitehill vs Bump Hadley | Seventh | 7 out |
| Thursday, May 8 |
| » Lost to Senators (13-7), 8-5 | Griffith Stadium (2-2) | 7-16 | |
| » Starters: Ownie Carroll vs Sad Sam Jones | Eighth | 8 out |
| Friday, May 9 |
| » Defeated Yankees (7-11), 5-4 | Yankee Stadium (1-0) | 8-16 | |
| » Starters: George Uhle vs Ed Wells | Seventh | 8 out |
| Saturday, May 10 |
| » Lost to Yankees (8-11), 14-5 | Yankee Stadium (1-1) | 8-17 | |
| » Starters: Chief Hogsett vs Lefty Gomez | Seventh | 9 out |
| Sunday, May 11 |
| » Lost to Yankees (9-11), 7-6 | Yankee Stadium (1-2) | 8-18 | Lost 2 |
| » Starters: Vic Sorrell vs Red Ruffing | Seventh | 9 out |
| Monday, May 12 |
| » Lost to Yankees (10-11), 7-0 | Yankee Stadium (1-3) | 8-19 | Lost 3 |
| » Starters: Earl Whitehill vs George Pipgras | Eighth | 10 out |
| Tuesday, May 13 |
| » Defeated Red Sox (11-14), 4-1 | Fenway Park (1-0) | 9-19 | |
| » Starters: Art Herring vs Jack Russell | Eighth | 10 out |
| Saturday, May 17 |
| » Defeated Browns (10-16), 12-7 | Tiger Stadium (5-6) | 10-19 | Won 2 |
| » Starters: General Crowder vs George Uhle | Eighth | 10 out |
| Monday, May 19 |
| » Defeated Browns (10-17), 5-4 | Tiger Stadium (6-6) | 11-19 | Won 3 |
| » Starters: Lefty Stewart vs Art Herring | Seventh | 8½ out |
| » Defeated Browns (10-18), 4-2 | Tiger Stadium (7-6) | 12-19 | Won 4 |
| » Starters: Sam Gray vs Whit Wyatt | Seventh | 8½ out |
| Tuesday, May 20 |
| » Lost to Browns (11-18), 8-2 | Tiger Stadium (7-7) | 12-20 | |
| » Starters: Dick Coffman vs Chief Hogsett | Eighth | 9 out |
| Wednesday, May 21 |
| » Lost to White Sox (12-16), 9-3 | Comiskey Park I (0-1) | 12-21 | Lost 2 |
| » Starters: Earl Whitehill vs Ted Lyons | Eighth | 10½ out |
| Thursday, May 22 |
| » Defeated White Sox (12-17), 6-1 | Comiskey Park I (1-1) | 13-21 | |
| » Starters: George Uhle vs Dutch Henry | Seventh | 11 out |
| Saturday, May 24 |
| » Lost to White Sox (13-17), 8-7 | Comiskey Park I (1-2) | 13-22 | |
| » Starters: Chief Hogsett vs Tommy Thomas | Seventh | 11½ out |
| Sunday, May 25 |
| » Defeated Browns (14-20), 9-8 | Sportsman's Park III (1-3) | 14-22 | |
| » Starters: Art Herring vs Dick Coffman | Seventh | 11½ out |
| Monday, May 26 |
| » Defeated Browns (14-21), 7-3 | Sportsman's Park III (2-3) | 15-22 | Won 2 |
| » Starters: Whit Wyatt vs George Blaeholder | Sixth | 11½ out |
| Tuesday, May 27 |
| » Defeated Browns (14-22), 16-11 | Sportsman's Park III (3-3) | 16-22 | Won 3 |
| » Starters: George Uhle vs Chad Kimsey | Fifth | 11½ out |
| Wednesday, May 28 |
| » Lost to Browns (15-22), 4-2 | Sportsman's Park III (3-4) | 16-23 | |
| » Starters: Earl Whitehill vs Lefty Stewart | Fifth | 12 out |
| Friday, May 30 |
| » Defeated Indians (22-17), 5-2 | League Park II (2-2) | 17-23 | |
| » Starters: Vic Sorrell vs Willis Hudlin | Fifth | 9½ out |
| » Defeated Indians (22-18), 9-6 | League Park II (3-2) | 18-23 | Won 2 |
| » Starters: Chief Hogsett vs Wes Ferrell | Fifth | 9½ out |
| » Major-league debuts: Belve Bean (Indians) |
| Saturday, May 31 |
| » Lost to Indians (23-18), 7-4 | League Park II (3-3) | 18-24 | |
| » Starters: Whit Wyatt vs Clint Brown | Fourth | 9½ out |
| Sunday, June 1 |
| » Lost to Indians (24-18), 3-2 | League Park II (3-4) | 18-25 | Lost 2 |
| » Starters: George Uhle vs Mel Harder | Fifth | 10½ out |
| Tuesday, June 3 |
| » Lost to Senators (28-15), 8-4 | Tiger Stadium (7-8) | 18-26 | Lost 3 |
| » Starters: Ad Liska vs Earl Whitehill | Fifth | 11½ out |
| Wednesday, June 4 |
| » Lost to Senators (29-15), 11-8 | Tiger Stadium (7-9) | 18-27 | Lost 4 |
| » Starters: Firpo Marberry vs Chief Hogsett | Sixth | 12½ out |
| Thursday, June 5 |
| » Defeated Senators (29-16), 6-2 | Tiger Stadium (8-9) | 19-27 | |
| » Starters: Sad Sam Jones vs Vic Sorrell | Sixth | 11½ out |
| Saturday, June 7 |
| » Defeated Red Sox (14-32), 6-0 | Tiger Stadium (9-9) | 20-27 | Won 2 |
| » Starters: Jack Russell vs George Uhle | Sixth | 11 out |
| Sunday, June 8 |
| » Defeated Red Sox (14-33), 1-0 | Tiger Stadium (10-9) | 21-27 | Won 3 |
| » Starters: Ed Morris vs Waite Hoyt | Fifth | 11 out |
| Monday, June 9 |
| » Lost to Red Sox (15-33), 7-6 | Tiger Stadium (10-10) | 21-28 | |
| » Starters: Milt Gaston vs Whit Wyatt | Fifth | 12 out |
| Tuesday, June 10 |
| » Lost to Red Sox (16-33), 12-6 | Tiger Stadium (10-11) | 21-29 | Lost 2 |
| » Starters: Hod Lisenbee vs Art Herring | Sixth | 12 out |
| Wednesday, June 11 |
| » Defeated Yankees (26-21), 13-7 | Tiger Stadium (11-11) | 22-29 | |
| » Starters: Ownie Carroll vs Vic Sorrell | Fifth | 11 out |
| Thursday, June 12 |
| » Lost to Yankees (27-21), 14-2 | Tiger Stadium (11-12) | 22-30 | |
| » Starters: Ed Wells vs Waite Hoyt | Sixth | 11 out |
| Friday, June 13 |
| » Lost to Yankees (28-21), 10-9 | Tiger Stadium (11-13) | 22-31 | Lost 2 |
| » Starters: George Pipgras vs Earl Whitehill | Sixth | 11 out |
| Saturday, June 14 |
| » Defeated Athletics (33-21), 11-2 | Tiger Stadium (12-13) | 23-31 | |
| » Starters: Roy Mahaffey vs George Uhle | Fifth | 10 out |
| Sunday, June 15 |
| » Lost to Athletics (34-21), 10-1 | Tiger Stadium (12-14) | 23-32 | |
| » Starters: Lefty Grove vs Vic Sorrell | Sixth | 11 out |
| Monday, June 16 |
| » Defeated Athletics (34-22), 9-8 | Tiger Stadium (13-14) | 24-32 | |
| » Starters: George Earnshaw vs Waite Hoyt | Fourth | 10 out |
| Thursday, June 19 |
| » Lost to Yankees (32-21), 5-4 | Yankee Stadium (1-4) | 24-33 | |
| » Starters: George Uhle vs Ed Wells | Sixth | 11½ out |
| Friday, June 20 |
| » Defeated Yankees (32-22), 11-6 | Yankee Stadium (2-4) | 25-33 | |
| » Starters: Vic Sorrell vs George Pipgras | Sixth | 11½ out |
| Saturday, June 21 |
| » Lost to Yankees (33-22), 3-0 | Yankee Stadium (2-5) | 25-34 | |
| » Starters: Chief Hogsett vs Herb Pennock | Sixth | 12½ out |
| Sunday, June 22 |
| » Defeated Red Sox (21-37), 5-3 | Braves Field (1-0) | 26-34 | |
| » Starters: Earl Whitehill vs Milt Gaston | Fifth | 11 out |
| » Defeated Red Sox (21-38), 4-2 | Braves Field (2-0) | 27-34 | Won 2 |
| » Starters: Waite Hoyt vs Ed Durham | Fifth | 11 out |
| » Major-league debuts: Gene Desautels (Tigers) |
| Monday, June 23 |
| » Lost to Red Sox (22-38), 2-0 | Fenway Park (1-1) | 27-35 | |
| » Starters: Charlie Sullivan vs Danny MacFayden | Fifth | 12½ out |
| Tuesday, June 24 |
| » Lost to Red Sox (23-38), 5-4 | Fenway Park (1-2) | 27-36 | Lost 2 |
| » Starters: George Uhle vs Hod Lisenbee | Fifth | 12½ out |
| » Defeated Red Sox (23-39), 8-7 | Fenway Park (2-2) | 28-36 | |
| » Starters: Vic Sorrell vs George Smith | Fifth | 12½ out |
| Wednesday, June 25 |
| » Defeated Red Sox (23-40), 4-3 | Fenway Park (3-2) | 29-36 | Won 2 |
| » Starters: Chief Hogsett vs Jack Russell | Fifth | 12 out |
| Thursday, June 26 |
| » Lost to Senators (39-24), 12-4 | Griffith Stadium (2-3) | 29-37 | |
| » Starters: Earl Whitehill vs Firpo Marberry | Fifth | 13 out |
| Friday, June 27 |
| » Lost to Senators (40-24), 6-4 | Griffith Stadium (2-4) | 29-38 | Lost 2 |
| » Starters: Charlie Sullivan vs General Crowder | Fifth | 13½ out |
| Saturday, June 28 |
| » Lost to Senators (41-24), 12-3 | Griffith Stadium (2-5) | 29-39 | Lost 3 |
| » Starters: Waite Hoyt vs Bump Hadley | Fifth | 14½ out |
| Sunday, June 29 |
| » Lost to Athletics (45-25), 6-5 | Tiger Stadium (13-15) | 29-40 | Lost 4 |
| » Starters: Bill Shores vs George Uhle | Fourth | 15½ out |
| Monday, June 30 |
| » Lost to Athletics (46-25), 3-1 | Shibe Park (0-4) | 29-41 | Lost 5 |
| » Starters: Vic Sorrell vs Eddie Rommel | Fourth | 16½ out |
| Tuesday, July 1 |
| » Lost to Athletics (47-25), 4-1 | Shibe Park (0-5) | 29-42 | Lost 6 |
| » Starters: Chief Hogsett vs Lefty Grove | Fifth | 17½ out |
| Wednesday, July 2 |
| » Defeated Athletics (47-26), 4-3 | Shibe Park (1-5) | 30-42 | |
| » Starters: Earl Whitehill vs Roy Mahaffey | Fifth | 17½ out |
| » Lost to Athletics (48-26), 7-2 | Shibe Park (1-6) | 30-43 | |
| » Starters: Waite Hoyt vs George Earnshaw | Fifth | 17½ out |
| Future Tiger Pete Burnside is born in Evanston, IL. |
| Friday, July 4 |
| » Defeated Indians (35-37), 5-4 | Tiger Stadium (14-15) | 31-43 | |
| » Starters: Wes Ferrell vs Vic Sorrell | Fifth | 17 out |
| » Defeated Indians (35-38), 4-3 | Tiger Stadium (15-15) | 32-43 | Won 2 |
| » Starters: Milt Shoffner vs George Uhle | Fifth | 17 out |
| Saturday, July 5 |
| » Defeated Indians (35-39), 8-6 | Tiger Stadium (16-15) | 33-43 | Won 3 |
| » Starters: Belve Bean vs Chief Hogsett | Fifth | 17 out |
| Sunday, July 6 |
| » Defeated White Sox (27-43), 5-2 | Comiskey Park I (2-2) | 34-43 | Won 4 |
| » Starters: Waite Hoyt vs Garland Braxton | Fifth | 17 out |
| Future Tiger Karl Olson is born in Kentfield, CA. |
| Monday, July 7 |
| » Defeated White Sox (27-44), 3-2 | Comiskey Park I (3-2) | 35-43 | Won 5 |
| » Starters: Earl Whitehill vs Dutch Henry | Fifth | 16½ out |
| » Lost to White Sox (28-44), 9-5 | Comiskey Park I (3-3) | 35-44 | |
| » Starters: Art Herring vs Pat Caraway | Fifth | 16½ out |
| Tuesday, July 8 |
| » Lost to White Sox (29-44), 3-2 | Comiskey Park I (3-4) | 35-45 | Lost 2 |
| » Starters: Vic Sorrell vs Ted Lyons | Fifth | 17½ out |
| Wednesday, July 9 |
| » Defeated White Sox (29-45), 6-1 | Comiskey Park I (4-4) | 36-45 | |
| » Starters: George Uhle vs Tommy Thomas | Fifth | 17 out |
| Thursday, July 10 |
| » Lost to Indians (39-40), 6-5 | Tiger Stadium (16-16) | 36-46 | |
| » Starters: Milt Shoffner vs Chief Hogsett | Fifth | 18 out |
| Friday, July 11 |
| » Defeated Indians (39-41), 11-1 | Tiger Stadium (17-16) | 37-46 | |
| » Starters: Clint Brown vs Waite Hoyt | Fifth | 17½ out |
| Saturday, July 12 |
| » Defeated Senators (52-27), 3-2 | Tiger Stadium (18-16) | 38-46 | Won 2 |
| » Starters: General Crowder vs Earl Whitehill | Fifth | 17½ out |
| » Lost to Senators (53-27), 7-5 | Tiger Stadium (18-17) | 38-47 | |
| » Starters: Firpo Marberry vs Chief Hogsett | Fifth | 17½ out |
| Sunday, July 13 |
| » Defeated Senators (53-28), 5-4 | Tiger Stadium (19-17) | 39-47 | |
| » Starters: Sad Sam Jones vs Vic Sorrell | Fifth | 17½ out |
| Monday, July 14 |
| » Defeated Senators (53-29), 8-4 | Tiger Stadium (20-17) | 40-47 | Won 2 |
| » Starters: Bump Hadley vs George Uhle | Fifth | 17½ out |
| Tuesday, July 15 |
| » Lost to Senators (54-29), 3-0 | Tiger Stadium (20-18) | 40-48 | |
| » Starters: Firpo Marberry vs Waite Hoyt | Fifth | 18½ out |
| Wednesday, July 16 |
| » Defeated Red Sox (31-53), 3-2 | Tiger Stadium (21-18) | 41-48 | |
| » Starters: Jack Russell vs Earl Whitehill | Fifth | 18½ out |
| Thursday, July 17 |
| » Lost to Red Sox (32-53), 12-2 | Tiger Stadium (21-19) | 41-49 | |
| » Starters: Hod Lisenbee vs Chief Hogsett | Fifth | 19½ out |
| Friday, July 18 |
| » Defeated Red Sox (32-54), 7-6 | Tiger Stadium (22-19) | 42-49 | |
| » Starters: Milt Gaston vs Vic Sorrell | Fifth | 19½ out |
| Saturday, July 19 |
| » Defeated Red Sox (32-55), 10-2 | Tiger Stadium (23-19) | 43-49 | Won 2 |
| » Starters: Danny MacFayden vs George Uhle | Fifth | 18½ out |
| Sunday, July 20 |
| » Lost to Athletics (62-30), 5-3 | Tiger Stadium (23-20) | 43-50 | |
| » Starters: Lefty Grove vs Waite Hoyt | Fifth | 19½ out |
| Monday, July 21 |
| » Defeated Athletics (62-31), 7-6 | Tiger Stadium (24-20) | 44-50 | |
| » Starters: George Earnshaw vs Earl Whitehill | Fifth | 18½ out |
| Tuesday, July 22 |
| » Defeated Athletics (62-32), 6-5 | Tiger Stadium (25-20) | 45-50 | Won 2 |
| » Starters: Bill Shores vs Vic Sorrell | Fifth | 17½ out |
| Wednesday, July 23 |
| » Lost to Athletics (63-32), 4-1 | Tiger Stadium (25-21) | 45-51 | |
| » Starters: Jack Quinn vs George Uhle | Fifth | 18½ out |
| Thursday, July 24 |
| » Lost to Yankees (54-40), 5-2 | Tiger Stadium (25-22) | 45-52 | Lost 2 |
| » Starters: Roy Sherid vs Guy Cantrell | Fifth | 19½ out |
| Friday, July 25 |
| » Lost to Yankees (55-40), 14-7 | Tiger Stadium (25-23) | 45-53 | Lost 3 |
| » Starters: Ed Wells vs Waite Hoyt | Fifth | 20½ out |
| Saturday, July 26 |
| » Defeated Yankees (55-41), 12-8 | Tiger Stadium (26-23) | 46-53 | |
| » Starters: George Pipgras vs Earl Whitehill | Fifth | 20½ out |
| Sunday, July 27 |
| » Defeated Yankees (55-42), 7-3 | Tiger Stadium (27-23) | 47-53 | Won 2 |
| » Starters: Red Ruffing vs Vic Sorrell | Fifth | 19½ out |
| Monday, July 28 |
| » Lost to Indians (51-49), 7-6 | League Park II (3-5) | 47-54 | |
| » Starters: George Uhle vs Clint Brown | Fifth | 20½ out |
| Future Tiger Ted Lepcio is born in Utica, NY. |
| Tuesday, July 29 |
| » Lost to Indians (52-49), 14-7 | League Park II (3-6) | 47-55 | Lost 2 |
| » Starters: Guy Cantrell vs Willis Hudlin | Fifth | 20½ out |
| Wednesday, July 30 |
| » Defeated Indians (52-50), 6-5 | League Park II (4-6) | 48-55 | |
| » Starters: Waite Hoyt vs Mel Harder | Fifth | 20½ out |
| Future Tiger Gus Triandos is born in San Francisco, CA. |
| Thursday, July 31 |
| » Lost to Indians (53-50), 5-3 | League Park II (4-7) | 48-56 | |
| » Starters: Vic Sorrell vs Wes Ferrell | Fifth | 21½ out |
| Friday, August 1 |
| » Defeated White Sox (43-59), 12-4 | Tiger Stadium (28-23) | 49-56 | |
| » Starters: Dutch Henry vs Earl Whitehill | Fifth | 21 out |
| Saturday, August 2 |
| » Defeated White Sox (43-60), 13-2 | Tiger Stadium (29-23) | 50-56 | Won 2 |
| » Starters: Tommy Thomas vs George Uhle | Fifth | 21½ out |
| Sunday, August 3 |
| » Defeated White Sox (43-61), 4-3 | Tiger Stadium (30-23) | 51-56 | Won 3 |
| » Starters: Pat Caraway vs Waite Hoyt | Fifth | 20½ out |
| Monday, August 4 |
| » Defeated White Sox (43-62), 7-3 | Tiger Stadium (31-23) | 52-56 | Won 4 |
| » Starters: Ted Lyons vs Vic Sorrell | Fifth | 20½ out |
| Tuesday, August 5 |
| » Defeated Indians (56-52), 5-4 | Tiger Stadium (32-23) | 53-56 | Won 5 |
| » Starters: Clint Brown vs Earl Whitehill | Fifth | 19½ out |
| Wednesday, August 6 |
| » Defeated Indians (56-53), 9-1 | Tiger Stadium (33-23) | 54-56 | Won 6 |
| » Starters: Willis Hudlin vs George Uhle | Fifth | 18½ out |
| Friday, August 8 |
| » Lost to Red Sox (38-72), 8-6 | Fenway Park (3-3) | 54-57 | |
| » Starters: Waite Hoyt vs Jack Russell | Fifth | 20½ out |
| Saturday, August 9 |
| » Defeated Red Sox (38-73), 3-0 | Fenway Park (4-3) | 55-57 | |
| » Starters: Vic Sorrell vs Hod Lisenbee | Fifth | 21 out |
| Future Tiger Milt Bolling is born in Mississippi City, MS. |
| Sunday, August 10 |
| » Defeated Red Sox (38-74), 4-2 | Braves Field (3-0) | 56-57 | Won 2 |
| » Starters: Earl Whitehill vs Ed Durham | Fifth | 20½ out |
| Monday, August 11 |
| » Lost to Red Sox (39-74), 5-1 | Fenway Park (4-4) | 56-58 | |
| » Starters: George Uhle vs Danny MacFayden | Fifth | 20½ out |
| Tuesday, August 12 |
| » Lost to Yankees (68-47), 6-5 | Yankee Stadium (2-6) | 56-59 | Lost 2 |
| » Starters: Waite Hoyt vs Ed Wells | Fifth | 22 out |
| Wednesday, August 13 |
| » Lost to Yankees (69-47), 10-8 | Yankee Stadium (2-7) | 56-60 | Lost 3 |
| » Starters: Vic Sorrell vs George Pipgras | Fifth | 23 out |
| » Major-league debuts: Tommy Bridges (Tigers) |
| Thursday, August 14 |
| » Defeated Yankees (69-48), 5-1 | Yankee Stadium (3-7) | 57-60 | |
| » Starters: Earl Whitehill vs Roy Sherid | Fifth | 22 out |
| Saturday, August 16 |
| » Lost to Senators (71-45), 3-1 | Griffith Stadium (2-6) | 57-61 | |
| » Starters: George Uhle vs Sad Sam Jones | Fifth | 23 out |
| Sunday, August 17 |
| » Defeated Senators (71-46), 15-1 | Griffith Stadium (3-6) | 58-61 | |
| » Starters: Vic Sorrell vs General Crowder | Fifth | 22½ out |
| Monday, August 18 |
| » Lost to Senators (72-46), 5-4 | Griffith Stadium (3-7) | 58-62 | |
| » Starters: Chief Hogsett vs Bump Hadley | Fifth | 23½ out |
| Tuesday, August 19 |
| » Defeated Senators (72-47), 2-1 | Griffith Stadium (4-7) | 59-62 | |
| » Starters: Earl Whitehill vs Lloyd Brown | Fifth | 22½ out |
| Wednesday, August 20 |
| » Lost to Athletics (83-40), 10-6 | Shibe Park (1-7) | 59-63 | |
| » Starters: Waite Hoyt vs Lefty Grove | Fifth | 23½ out |
| Thursday, August 21 |
| » Lost to Athletics (84-40), 8-7 | Shibe Park (1-8) | 59-64 | Lost 2 |
| » Starters: George Uhle vs Bill Shores | Fifth | 24½ out |
| Friday, August 22 |
| » Defeated Athletics (84-41), 7-1 | Shibe Park (2-8) | 60-64 | |
| » Starters: Vic Sorrell vs George Earnshaw | Fifth | 23½ out |
| Saturday, August 23 |
| » Lost to Athletics (85-41), 2-0 | Shibe Park (2-9) | 60-65 | |
| » Starters: Charlie Sullivan vs George Earnshaw | Fifth | 24½ out |
| Sunday, August 24 |
| » Lost to Browns (49-76), 7-5 | Tiger Stadium (33-24) | 60-66 | Lost 2 |
| » Starters: Rollie Stiles vs Earl Whitehill | Fifth | 24½ out |
| Monday, August 25 |
| » Defeated Browns (49-77), 7-5 | Tiger Stadium (34-24) | 61-66 | |
| » Starters: Dick Coffman vs Tommy Bridges | Fifth | 23½ out |
| Wednesday, August 27 |
| » Lost to Browns (50-77), 5-0 | Sportsman's Park III (3-5) | 61-67 | |
| » Starters: George Uhle vs Lefty Stewart | Fifth | 24½ out |
| Thursday, August 28 |
| » Lost to Browns (51-77), 9-1 | Sportsman's Park III (3-6) | 61-68 | Lost 2 |
| » Starters: Vic Sorrell vs George Blaeholder | Fifth | 24½ out |
| Friday, August 29 |
| » Lost to Browns (52-77), 9-6 | Sportsman's Park III (3-7) | 61-69 | Lost 3 |
| » Starters: Earl Whitehill vs Dick Coffman | Fifth | 25 out |
| Saturday, August 30 |
| » Lost to Browns (53-77), 6-5 | Sportsman's Park III (3-8) | 61-70 | Lost 4 |
| » Starters: Waite Hoyt vs Rollie Stiles | Fifth | 26 out |
| Sunday, August 31 |
| » Defeated White Sox (51-78), 4-1 | Comiskey Park I (5-4) | 62-70 | |
| » Starters: Tommy Bridges vs Jim Moore | Fifth | 26 out |
| » Major-league debuts: Jimmy Moore (White Sox) |
| Monday, September 1 |
| » Defeated White Sox (51-79), 6-5 | Comiskey Park I (6-4) | 63-70 | Won 2 |
| » Starters: George Uhle vs Ted Lyons | Fifth | 25 out |
| » Defeated White Sox (51-80), 4-2 | Comiskey Park I (7-4) | 64-70 | Won 3 |
| » Starters: Earl Whitehill vs Tommy Thomas | Fifth | 25 out |
| Thursday, September 4 |
| » Defeated Browns (53-82), 8-4 | Tiger Stadium (35-24) | 65-70 | Won 4 |
| » Starters: George Blaeholder vs Vic Sorrell | Fifth | 25½ out |
| » Major-league debuts: Frank Doljack (Tigers) |
| Friday, September 5 |
| Future Tiger Wayne Belardi is born in St. Helena, CA. |
| Saturday, September 6 |
| » Defeated Browns (53-83), 8-4 | Tiger Stadium (36-24) | 66-70 | Won 5 |
| » Starters: Dick Coffman vs Whit Wyatt | Fifth | 26 out |
| Sunday, September 7 |
| » Lost to Browns (54-83), 9-6 | Tiger Stadium (36-25) | 66-71 | |
| » Starters: Lefty Stewart vs Tommy Bridges | Fifth | 26 out |
| Tuesday, September 9 |
| » Lost to Athletics (94-46), 3-1 | Tiger Stadium (36-26) | 66-72 | Lost 2 |
| » Starters: Lefty Grove vs Earl Whitehill | Fifth | 27 out |
| » Major-league debuts: Tom Hughes (Tigers) |
| Wednesday, September 10 |
| » Defeated Athletics (94-47), 4-0 | Tiger Stadium (37-26) | 67-72 | |
| » Starters: Bill Shores vs Vic Sorrell | Fifth | 26 out |
| Friday, September 12 |
| » Defeated Yankees (79-61), 5-4 | Tiger Stadium (38-26) | 68-72 | Won 2 |
| » Starters: Roy Sherid vs Whit Wyatt | Fifth | 25½ out |
| Saturday, September 13 |
| » Defeated Yankees (79-62), 11-10 | Tiger Stadium (39-26) | 69-72 | Won 3 |
| » Starters: Ed Wells vs George Uhle | Fifth | 25 out |
| » Defeated Yankees (79-63), 9-4 | Tiger Stadium (40-26) | 70-72 | Won 4 |
| » Starters: George Pipgras vs Tommy Bridges | Fifth | 25 out |
| Sunday, September 14 |
| » Lost to Yankees (80-63), 10-3 | Tiger Stadium (40-27) | 70-73 | |
| » Starters: Red Ruffing vs Earl Whitehill | Fifth | 26 out |
| » Major-league debuts: Hank Greenberg (Tigers) |
| Monday, September 15 |
| » Lost to Yankees (81-63), 5-3 | Tiger Stadium (40-28) | 70-74 | Lost 2 |
| » Starters: Roy Sherid vs Vic Sorrell | Fifth | 26½ out |
| Tuesday, September 16 |
| » Defeated Red Sox (47-97), 7-5 | Tiger Stadium (41-28) | 71-74 | |
| » Starters: Milt Gaston vs Waite Hoyt | Fifth | 27 out |
| Wednesday, September 17 |
| » Defeated Red Sox (47-98), 9-7 | Tiger Stadium (42-28) | 72-74 | Won 2 |
| » Starters: Ed Durham vs Earl Whitehill | Fifth | 26 out |
| » Major-league debuts: Bob Kline (Red Sox) |
| Thursday, September 18 |
| » Lost to Red Sox (48-98), 4-3 | Tiger Stadium (42-29) | 72-75 | |
| » Starters: Hod Lisenbee vs Tommy Bridges | Fifth | 27 out |
| Friday, September 19 |
| » Lost to Senators (91-56), 8-4 | Tiger Stadium (42-30) | 72-76 | Lost 2 |
| » Starters: General Crowder vs Vic Sorrell | Fifth | 27½ out |
| Saturday, September 20 |
| » Defeated Senators (91-57), 4-1 | Tiger Stadium (43-30) | 73-76 | |
| » Starters: Lloyd Brown vs Waite Hoyt | Fifth | 26½ out |
| Sunday, September 21 |
| » Defeated Senators (91-58), 4-3 | Tiger Stadium (44-30) | 74-76 | Won 2 |
| » Starters: Bump Hadley vs Earl Whitehill | Fifth | 26 out |
| Friday, September 26 |
| » Lost to White Sox (60-91), 3-1 | Tiger Stadium (44-31) | 74-77 | |
| » Starters: Ted Lyons vs Waite Hoyt | Fifth | 27½ out |
| Saturday, September 27 |
| » Defeated White Sox (60-92), 6-5 | Tiger Stadium (45-31) | 75-77 | |
| » Starters: Tommy Thomas vs Vic Sorrell | Fifth | 27 out |
| » Lost to White Sox (61-92), 10-5 | Tiger Stadium (45-32) | 75-78 | |
| » Starters: Red Faber vs Mark Koenig | Fifth | 27 out |
| Sunday, September 28 |
| » Lost to White Sox (62-92), 10-7 | Tiger Stadium (45-33) | 75-79 | Lost 2 |
| » Starters: Jim Moore vs Earl Whitehill | Fifth | 27 out |
| Saturday, November 8 |