| Saturday, January 4 |
| Future Red Sox Don McMahon is born in Brooklyn, NY. |
| Tuesday, January 14 |
| Future Red Sox Pete Daley is born in Grass Valley, CA. |
| Thursday, January 23 |
| Future Red Sox Frank Sullivan is born in Hollywood, CA. |
| Friday, February 28 |
| Future Red Sox Frank Malzone is born in Bronx, NY. |
| Tuesday, March 25 |
| Future Red Sox Rudy Minarcin is born in North Vandergrift, PA. |
| Monday, April 14 |
| » Defeated Senators (0-1), 4-3 | Griffith Stadium (1-0) | 1-0 | |
| » Starters: Danny MacFayden vs Firpo Marberry | First | -- |
| » Major-league debuts: Tom Oliver (Red Sox) |
| Tuesday, April 15 |
| » Lost to Senators (1-1), 6-1 | Fenway Park (0-1) | 1-1 | |
| » Starters: Lloyd Brown vs Red Ruffing | Third | ½ out |
| » Major-league debuts: Frank Mulroney (Red Sox) |
| Wednesday, April 16 |
| » Lost to Senators (2-1), 5-4 | Fenway Park (0-2) | 1-2 | Lost 2 |
| » Starters: Bump Hadley vs Milt Gaston | Fourth | 1 out |
| Saturday, April 19 |
| » Defeated Yankees (0-2), 4-3 | Fenway Park (1-2) | 2-2 | |
| » Starters: Waite Hoyt vs Hod Lisenbee | Third | 1½ out |
| » Defeated Yankees (0-3), 7-2 | Fenway Park (2-2) | 3-2 | Won 2 |
| » Starters: Herb Pennock vs Jack Russell | Third | 1½ out |
| » Major-league debuts: Jimmie Reese (Yankees) |
| Sunday, April 20 |
| » Lost to Athletics (3-0), 5-3 | Braves Field (0-1) | 3-3 | |
| » Starters: Eddie Rommel vs Danny MacFayden | Fifth | 1½ out |
| » Major-league debuts: Tom Winsett (Red Sox) |
| Tuesday, April 22 |
| » Lost to Senators (5-2), 4-3 | Griffith Stadium (1-1) | 3-4 | Lost 2 |
| » Starters: Red Ruffing vs Bobby Burke | Fifth | 2 out |
| Friday, April 25 |
| » Lost to Yankees (1-5), 3-2 | Yankee Stadium (0-1) | 3-5 | Lost 3 |
| » Starters: Milt Gaston vs Hank Johnson | Sixth | 3 out |
| Saturday, April 26 |
| » Lost to Yankees (2-5), 8-3 | Yankee Stadium (0-2) | 3-6 | Lost 4 |
| » Starters: Hod Lisenbee vs George Pipgras | Sixth | 4 out |
| Sunday, April 27 |
| » Defeated Yankees (2-6), 8-7 | Yankee Stadium (1-2) | 4-6 | |
| » Starters: Jack Russell vs Waite Hoyt | Sixth | 4 out |
| Monday, April 28 |
| » Lost to Athletics (5-4), 5-4 | Fenway Park (2-3) | 4-7 | |
| » Starters: George Earnshaw vs Danny MacFayden | Sixth | 5 out |
| Tuesday, April 29 |
| » Lost to Athletics (6-4), 9-5 | Fenway Park (2-4) | 4-8 | Lost 2 |
| » Starters: George Earnshaw vs Red Ruffing | Sixth | 6 out |
| Wednesday, April 30 |
| » Defeated Athletics (6-5), 7-3 | Fenway Park (3-4) | 5-8 | |
| » Starters: Jack Quinn vs Milt Gaston | Sixth | 5 out |
| Friday, May 2 |
| » Lost to Indians (9-4), 8-3 | Fenway Park (3-5) | 5-9 | |
| » Starters: Wes Ferrell vs Hod Lisenbee | Sixth | 6 out |
| Saturday, May 3 |
| » Lost to Indians (10-4), 6-5 | Fenway Park (3-6) | 5-10 | Lost 2 |
| » Starters: Pete Appleton vs Jack Russell | Sixth | 6 out |
| Sunday, May 4 |
| » Lost to Indians (11-4), 8-7 | Braves Field (0-2) | 5-11 | Lost 3 |
| » Starters: Clint Brown vs Danny MacFayden | Seventh | 6½ out |
| Monday, May 5 |
| » Defeated Indians (11-5), 18-3 | Fenway Park (4-6) | 6-11 | |
| » Starters: Willis Hudlin vs Milt Gaston | Sixth | 5½ out |
| Tuesday, May 6 |
| » Lost to White Sox (8-7), 4-3 | Fenway Park (4-7) | 6-12 | |
| » Starters: Ted Lyons vs Ed Morris | Sixth | 6½ out |
| Wednesday, May 7 |
| » Defeated White Sox (8-8), 6-4 | Fenway Park (5-7) | 7-12 | |
| » Starters: Hal McKain vs Hod Lisenbee | Sixth | 5½ out |
| Thursday, May 8 |
| » Defeated White Sox (8-9), 3-1 | Fenway Park (6-7) | 8-12 | Won 2 |
| » Starters: Tommy Thomas vs Jack Russell | Seventh | 5½ out |
| Friday, May 9 |
| » Defeated Browns (9-12), 5-2 | Fenway Park (7-7) | 9-12 | Won 3 |
| » Starters: General Crowder vs Danny MacFayden | Fifth | 5½ out |
| Saturday, May 10 |
| » Defeated Browns (9-13), 2-0 | Fenway Park (8-7) | 10-12 | Won 4 |
| » Starters: Sam Gray vs Milt Gaston | Fourth | 5½ out |
| Sunday, May 11 |
| » Defeated Browns (9-14), 2-1 | Braves Field (1-2) | 11-12 | Won 5 |
| » Starters: Lefty Stewart vs Ed Morris | Fourth | 4½ out |
| Monday, May 12 |
| » Lost to Browns (10-14), 3-2 | Fenway Park (8-8) | 11-13 | |
| » Starters: Rip Collins vs Hod Lisenbee | Fifth | 5½ out |
| Future Red Sox Tommy Umphlett is born in Scotland Neck, NC. |
| Tuesday, May 13 |
| » Lost to Tigers (9-19), 4-1 | Fenway Park (8-9) | 11-14 | Lost 2 |
| » Starters: Art Herring vs Jack Russell | Fifth | 6½ out |
| Friday, May 16 |
| » Defeated Yankees (11-12), 5-4 | Fenway Park (9-9) | 12-14 | |
| » Starters: Lefty Gomez vs Danny MacFayden | Fifth | 6 out |
| Saturday, May 17 |
| » Lost to Yankees (12-12), 3-2 | Fenway Park (9-10) | 12-15 | |
| » Starters: Red Ruffing vs Milt Gaston | Sixth | 7 out |
| Sunday, May 18 |
| » Lost to Yankees (13-12), 11-0 | Braves Field (1-3) | 12-16 | Lost 2 |
| » Starters: George Pipgras vs Ed Morris | Sixth | 7 out |
| Tuesday, May 20 |
| » Lost to Yankees (14-12), 7-4 | Fenway Park (9-11) | 12-17 | Lost 3 |
| » Starters: Waite Hoyt vs Hod Lisenbee | Fifth | 7½ out |
| Wednesday, May 21 |
| » Lost to Senators (21-10), 10-2 | Griffith Stadium (1-2) | 12-18 | Lost 4 |
| » Starters: Jack Russell vs Sad Sam Jones | Seventh | 9½ out |
| » Lost to Senators (22-10), 6-1 | Griffith Stadium (1-3) | 12-19 | Lost 5 |
| » Starters: Danny MacFayden vs Ad Liska | Seventh | 9½ out |
| Thursday, May 22 |
| » Lost to Senators (23-10), 3-2 | Griffith Stadium (1-4) | 12-20 | Lost 6 |
| » Starters: Milt Gaston vs Bump Hadley | Eighth | 11½ out |
| » Lost to Senators (24-10), 13-1 | Griffith Stadium (1-5) | 12-21 | Lost 7 |
| » Starters: Ed Morris vs Bobby Burke | Eighth | 11½ out |
| Sunday, May 25 |
| » Lost to Senators (25-10), 5-0 | Griffith Stadium (1-6) | 12-22 | Lost 8 |
| » Starters: Ed Durham vs Firpo Marberry | Eighth | 12½ out |
| Monday, May 26 |
| » Lost to Athletics (22-14), 8-5 | Shibe Park (0-1) | 12-23 | Lost 9 |
| » Starters: Jack Russell vs Lefty Grove | Eighth | 13½ out |
| Tuesday, May 27 |
| » Lost to Athletics (23-14), 7-5 | Shibe Park (0-2) | 12-24 | Lost 10 |
| » Starters: Danny MacFayden vs George Earnshaw | Eighth | 14½ out |
| Thursday, May 29 |
| » Lost to Athletics (24-14), 2-1 | Shibe Park (0-3) | 12-25 | Lost 11 |
| » Starters: Milt Gaston vs Roy Mahaffey | Eighth | 14½ out |
| Friday, May 30 |
| » Lost to Yankees (20-17), 6-5 | Yankee Stadium (1-3) | 12-26 | Lost 12 |
| » Starters: Hod Lisenbee vs Herb Pennock | Eighth | 14½ out |
| » Lost to Yankees (21-17), 7-3 | Yankee Stadium (1-4) | 12-27 | Lost 13 |
| » Starters: Ed Durham vs Red Ruffing | Eighth | 14½ out |
| Saturday, May 31 |
| » Lost to Yankees (22-17), 5-2 | Yankee Stadium (1-5) | 12-28 | Lost 14 |
| » Starters: Jack Russell vs Ed Wells | Seventh | 14½ out |
| Sunday, June 1 |
| » Defeated Yankees (22-18), 7-4 | Yankee Stadium (2-5) | 13-28 | |
| » Starters: Danny MacFayden vs Hank Johnson | Eighth | 14½ out |
| Tuesday, June 3 |
| » Lost to Indians (25-18), 8-3 | League Park II (0-1) | 13-29 | |
| » Starters: Jack Russell vs Wes Ferrell | Eighth | 15½ out |
| Wednesday, June 4 |
| » Defeated Indians (25-19), 5-4 | League Park II (1-1) | 14-29 | |
| » Starters: Ed Morris vs Willis Hudlin | Eighth | 15½ out |
| Thursday, June 5 |
| » Lost to Indians (26-19), 17-7 | League Park II (1-2) | 14-30 | |
| » Starters: Milt Gaston vs Clint Brown | Eighth | 15½ out |
| Friday, June 6 |
| » Lost to Indians (27-19), 9-4 | League Park II (1-3) | 14-31 | Lost 2 |
| » Starters: Danny MacFayden vs Mel Harder | Eighth | 16½ out |
| Saturday, June 7 |
| » Lost to Tigers (20-27), 6-0 | Tiger Stadium (0-1) | 14-32 | Lost 3 |
| » Starters: Jack Russell vs George Uhle | Eighth | 16½ out |
| Sunday, June 8 |
| » Lost to Tigers (21-27), 1-0 | Tiger Stadium (0-2) | 14-33 | Lost 4 |
| » Starters: Ed Morris vs Waite Hoyt | Eighth | 17½ out |
| Monday, June 9 |
| » Defeated Tigers (21-28), 7-6 | Tiger Stadium (1-2) | 15-33 | |
| » Starters: Milt Gaston vs Whit Wyatt | Eighth | 17½ out |
| Tuesday, June 10 |
| » Defeated Tigers (21-29), 12-6 | Tiger Stadium (2-2) | 16-33 | Won 2 |
| » Starters: Hod Lisenbee vs Art Herring | Eighth | 16½ out |
| Thursday, June 12 |
| » Lost to Browns (20-30), 6-5 | Sportsman's Park III (0-1) | 16-34 | |
| » Starters: Jack Russell vs Lefty Stewart | Eighth | 16 out |
| Friday, June 13 |
| » Lost to Browns (21-30), 1-0 | Sportsman's Park III (0-2) | 16-35 | Lost 2 |
| » Starters: Milt Gaston vs Rip Collins | Eighth | 16 out |
| Saturday, June 14 |
| » Defeated White Sox (20-29), 8-4 | Comiskey Park I (1-0) | 17-35 | |
| » Starters: Danny MacFayden vs Red Faber | Eighth | 15 out |
| Monday, June 16 |
| » Defeated White Sox (20-30), 6-3 | Comiskey Park I (2-0) | 18-35 | Won 2 |
| » Starters: Jack Russell vs Ted Lyons | Seventh | 14½ out |
| Tuesday, June 17 |
| » Defeated White Sox (20-31), 8-5 | Comiskey Park I (3-0) | 19-35 | Won 3 |
| » Starters: Milt Gaston vs Ed Walsh | Seventh | 14 out |
| Thursday, June 19 |
| » Defeated Browns (24-32), 4-1 | Fenway Park (10-11) | 20-35 | Won 4 |
| » Starters: Rip Collins vs Danny MacFayden | Eighth | 14½ out |
| » Major-league debuts: Rollie Stiles (Browns) |
| Friday, June 20 |
| » Lost to Browns (25-32), 4-3 | Fenway Park (10-12) | 20-36 | |
| » Starters: Sam Gray vs Hod Lisenbee | Eighth | 15½ out |
| Saturday, June 21 |
| » Defeated Browns (25-33), 3-2 | Fenway Park (11-12) | 21-36 | |
| » Starters: Lefty Stewart vs Jack Russell | Eighth | 15½ out |
| Sunday, June 22 |
| » Lost to Tigers (26-34), 5-3 | Braves Field (1-4) | 21-37 | |
| » Starters: Earl Whitehill vs Milt Gaston | Eighth | 16 out |
| » Lost to Tigers (27-34), 4-2 | Braves Field (1-5) | 21-38 | Lost 2 |
| » Starters: Waite Hoyt vs Ed Durham | Eighth | 16 out |
| » Major-league debuts: Gene Desautels (Tigers) |
| Monday, June 23 |
| » Defeated Tigers (27-35), 2-0 | Fenway Park (12-12) | 22-38 | |
| » Starters: Charlie Sullivan vs Danny MacFayden | Seventh | 16½ out |
| Tuesday, June 24 |
| » Defeated Tigers (27-36), 5-4 | Fenway Park (13-12) | 23-38 | Won 2 |
| » Starters: George Uhle vs Hod Lisenbee | Eighth | 16½ out |
| » Lost to Tigers (28-36), 8-7 | Fenway Park (13-13) | 23-39 | |
| » Starters: Vic Sorrell vs George Smith | Eighth | 16½ out |
| Wednesday, June 25 |
| » Lost to Tigers (29-36), 4-3 | Fenway Park (13-14) | 23-40 | Lost 2 |
| » Starters: Chief Hogsett vs Jack Russell | Eighth | 17 out |
| Thursday, June 26 |
| » Defeated White Sox (23-37), 9-7 | Fenway Park (14-14) | 24-40 | |
| » Starters: Tommy Thomas vs Milt Gaston | Eighth | 17 out |
| Saturday, June 28 |
| » Defeated White Sox (23-38), 4-2 | Fenway Park (15-14) | 25-40 | Won 2 |
| » Starters: Dutch Henry vs Danny MacFayden | Seventh | 17 out |
| Sunday, June 29 |
| » Defeated White Sox (23-39), 10-6 | Braves Field (2-5) | 26-40 | Won 3 |
| » Starters: Red Faber vs Hod Lisenbee | Fifth | 17½ out |
| » Lost to White Sox (24-39), 2-1 | Braves Field (2-6) | 26-41 | |
| » Starters: Ted Lyons vs Jack Russell | Fifth | 17½ out |
| Monday, June 30 |
| » Lost to Indians (35-34), 8-3 | Fenway Park (15-15) | 26-42 | Lost 2 |
| » Starters: Belve Bean vs Ed Morris | Fifth | 18½ out |
| Tuesday, July 1 |
| » Defeated Indians (35-35), 3-1 | Fenway Park (16-15) | 27-42 | |
| » Starters: Mel Harder vs Milt Gaston | Sixth | 18½ out |
| Wednesday, July 2 |
| » Defeated Indians (35-36), 5-4 | Fenway Park (17-15) | 28-42 | Won 2 |
| » Starters: Clint Brown vs Danny MacFayden | Seventh | 18 out |
| Friday, July 4 |
| » Defeated Athletics (49-27), 7-6 | Fenway Park (18-15) | 29-42 | Won 3 |
| » Starters: Lefty Grove vs Jack Russell | Seventh | 18½ out |
| » Lost to Athletics (50-27), 4-2 | Fenway Park (18-16) | 29-43 | |
| » Starters: Eddie Rommel vs Hod Lisenbee | Seventh | 18½ out |
| Saturday, July 5 |
| » Lost to Athletics (51-27), 7-2 | Fenway Park (18-17) | 29-44 | Lost 2 |
| » Starters: Roy Mahaffey vs Milt Gaston | Seventh | 19½ out |
| Sunday, July 6 |
| » Lost to Athletics (52-27), 4-3 | Braves Field (2-7) | 29-45 | Lost 3 |
| » Starters: George Earnshaw vs Danny MacFayden | Seventh | 20½ out |
| Monday, July 7 |
| » Lost to Senators (49-25), 8-1 | Fenway Park (18-18) | 29-46 | Lost 4 |
| » Starters: General Crowder vs Ed Morris | Eighth | 20½ out |
| Tuesday, July 8 |
| » Lost to Senators (50-25), 6-5 | Fenway Park (18-19) | 29-47 | Lost 5 |
| » Starters: Firpo Marberry vs Hod Lisenbee | Eighth | 21½ out |
| Wednesday, July 9 |
| » Lost to Senators (51-25), 5-2 | Fenway Park (18-20) | 29-48 | Lost 6 |
| » Starters: Sad Sam Jones vs Jack Russell | Eighth | 21½ out |
| » Defeated Senators (51-26), 5-1 | Fenway Park (19-20) | 30-48 | |
| » Starters: Lloyd Brown vs Milt Gaston | Eighth | 21½ out |
| Thursday, July 10 |
| » Lost to Senators (52-26), 7-2 | Fenway Park (19-21) | 30-49 | |
| » Starters: Bump Hadley vs Danny MacFayden | Eighth | 22½ out |
| Saturday, July 12 |
| » Lost to Indians (40-41), 12-3 | League Park II (1-4) | 30-50 | Lost 2 |
| » Starters: Hod Lisenbee vs Willis Hudlin | Eighth | 23 out |
| Sunday, July 13 |
| » Lost to Indians (41-41), 11-3 | League Park II (1-5) | 30-51 | Lost 3 |
| » Starters: Jack Russell vs Mel Harder | Eighth | 24 out |
| Monday, July 14 |
| » Lost to Indians (42-41), 3-2 | League Park II (1-6) | 30-52 | Lost 4 |
| » Starters: Milt Gaston vs Wes Ferrell | Eighth | 25 out |
| Tuesday, July 15 |
| » Defeated Indians (42-42), 13-4 | League Park II (2-6) | 31-52 | |
| » Starters: Danny MacFayden vs Clint Brown | Eighth | 25 out |
| Wednesday, July 16 |
| » Lost to Tigers (41-48), 3-2 | Tiger Stadium (2-3) | 31-53 | |
| » Starters: Jack Russell vs Earl Whitehill | Eighth | 26 out |
| Thursday, July 17 |
| » Defeated Tigers (41-49), 12-2 | Tiger Stadium (3-3) | 32-53 | |
| » Starters: Hod Lisenbee vs Chief Hogsett | Seventh | 26 out |
| Friday, July 18 |
| » Lost to Tigers (42-49), 7-6 | Tiger Stadium (3-4) | 32-54 | |
| » Starters: Milt Gaston vs Vic Sorrell | Eighth | 27 out |
| Saturday, July 19 |
| » Lost to Tigers (43-49), 10-2 | Tiger Stadium (3-5) | 32-55 | Lost 2 |
| » Starters: Danny MacFayden vs George Uhle | Eighth | 27 out |
| Sunday, July 20 |
| » Lost to White Sox (34-53), 16-4 | Comiskey Park I (3-1) | 32-56 | Lost 3 |
| » Starters: Jack Russell vs Ted Lyons | Eighth | 28½ out |
| » Lost to White Sox (35-53), 5-4 | Comiskey Park I (3-2) | 32-57 | Lost 4 |
| » Starters: George Smith vs Pat Caraway | Eighth | 28½ out |
| Monday, July 21 |
| » Defeated White Sox (35-54), 3-1 | Comiskey Park I (4-2) | 33-57 | |
| » Starters: Hod Lisenbee vs Tommy Thomas | Eighth | 27½ out |
| Tuesday, July 22 |
| » Defeated White Sox (35-55), 4-3 | Comiskey Park I (5-2) | 34-57 | Won 2 |
| » Starters: Milt Gaston vs Dutch Henry | Eighth | 26½ out |
| Wednesday, July 23 |
| » Lost to White Sox (36-55), 5-3 | Comiskey Park I (5-3) | 34-58 | |
| » Starters: Danny MacFayden vs Red Faber | Eighth | 27½ out |
| Thursday, July 24 |
| » Defeated Browns (36-58), 8-5 | Sportsman's Park III (1-2) | 35-58 | |
| » Starters: Jack Russell vs Rollie Stiles | Eighth | 27½ out |
| » Major-league debuts: Rabbit Warstler (Red Sox) |
| Friday, July 25 |
| » Lost to Browns (37-58), 6-3 | Sportsman's Park III (1-3) | 35-59 | |
| » Starters: Hod Lisenbee vs George Blaeholder | Eighth | 28½ out |
| Saturday, July 26 |
| » Lost to Browns (38-58), 6-3 | Sportsman's Park III (1-4) | 35-60 | Lost 2 |
| » Starters: Milt Gaston vs Lefty Stewart | Eighth | 29½ out |
| Sunday, July 27 |
| » Lost to Browns (39-58), 10-9 | Sportsman's Park III (1-5) | 35-61 | Lost 3 |
| » Starters: Danny MacFayden vs Dick Coffman | Eighth | 30 out |
| » Lost to Browns (40-58), 9-6 | Sportsman's Park III (1-6) | 35-62 | Lost 4 |
| » Starters: Hod Lisenbee vs Sam Gray | Eighth | 30 out |
| Monday, July 28 |
| Future Red Sox Ted Lepcio is born in Utica, NY. |
| Wednesday, July 30 |
| » Lost to Yankees (57-43), 8-2 | Fenway Park (19-22) | 35-63 | Lost 5 |
| » Starters: Herb Pennock vs Milt Gaston | Eighth | 31½ out |
| » Lost to Yankees (58-43), 10-1 | Fenway Park (19-23) | 35-64 | Lost 6 |
| » Starters: George Pipgras vs Jack Russell | Eighth | 31½ out |
| Thursday, July 31 |
| » Lost to Yankees (59-43), 14-13 | Fenway Park (19-24) | 35-65 | Lost 7 |
| » Starters: Ed Wells vs Danny MacFayden | Eighth | 32½ out |
| Friday, August 1 |
| » Lost to Yankees (60-43), 4-1 | Fenway Park (19-25) | 35-66 | Lost 8 |
| » Starters: Red Ruffing vs Hod Lisenbee | Eighth | 33 out |
| Saturday, August 2 |
| » Lost to Athletics (70-34), 9-2 | Shibe Park (0-4) | 35-67 | Lost 9 |
| » Starters: Ed Morris vs Bill Shores | Eighth | 35 out |
| » Lost to Athletics (71-34), 8-7 | Shibe Park (0-5) | 35-68 | Lost 10 |
| » Starters: Danny MacFayden vs Eddie Rommel | Eighth | 35 out |
| Sunday, August 3 |
| » Lost to Senators (62-40), 11-2 | Griffith Stadium (1-7) | 35-69 | Lost 11 |
| » Starters: Milt Gaston vs General Crowder | Eighth | 34½ out |
| » Defeated Senators (62-41), 7-1 | Griffith Stadium (2-7) | 36-69 | |
| » Starters: Jack Russell vs Ad Liska | Eighth | 34½ out |
| » Major-league debuts: Jake Powell (Senators) |
| Monday, August 4 |
| » Lost to Athletics (72-35), 13-4 | Shibe Park (0-6) | 36-70 | |
| » Starters: Hod Lisenbee vs Lefty Grove | Eighth | 35½ out |
| Tuesday, August 5 |
| » Defeated Athletics (72-36), 4-3 | Shibe Park (1-6) | 37-70 | |
| » Starters: Ed Durham vs Roy Mahaffey | Eighth | 34½ out |
| Wednesday, August 6 |
| » Lost to Yankees (63-46), 4-2 | Yankee Stadium (2-6) | 37-71 | |
| » Starters: Milt Gaston vs Roy Sherid | Eighth | 34½ out |
| Thursday, August 7 |
| » Lost to Yankees (64-46), 5-1 | Yankee Stadium (2-7) | 37-72 | Lost 2 |
| » Starters: Danny MacFayden vs Ed Wells | Eighth | 35½ out |
| Friday, August 8 |
| » Defeated Tigers (54-57), 8-6 | Fenway Park (20-25) | 38-72 | |
| » Starters: Waite Hoyt vs Jack Russell | Eighth | 36 out |
| Saturday, August 9 |
| » Lost to Tigers (55-57), 3-0 | Fenway Park (20-26) | 38-73 | |
| » Starters: Vic Sorrell vs Hod Lisenbee | Eighth | 37½ out |
| Future Red Sox Milt Bolling is born in Mississippi City, MS. Future Red Sox Roman Mejias is born in Abreus, Cuba. |
| Sunday, August 10 |
| » Lost to Tigers (56-57), 4-2 | Braves Field (2-8) | 38-74 | Lost 2 |
| » Starters: Earl Whitehill vs Ed Durham | Eighth | 38 out |
| Monday, August 11 |
| » Defeated Tigers (56-58), 5-1 | Fenway Park (21-26) | 39-74 | |
| » Starters: George Uhle vs Danny MacFayden | Eighth | 37 out |
| Tuesday, August 12 |
| » Defeated Browns (45-70), 5-4 | Fenway Park (22-26) | 40-74 | Won 2 |
| » Starters: Chad Kimsey vs Milt Gaston | Eighth | 37½ out |
| Wednesday, August 13 |
| » Lost to Browns (46-70), 7-2 | Fenway Park (22-27) | 40-75 | |
| » Starters: Lefty Stewart vs Jack Russell | Eighth | 38½ out |
| Thursday, August 14 |
| » Defeated Browns (46-71), 3-0 | Fenway Park (23-27) | 41-75 | |
| » Starters: George Blaeholder vs Ed Durham | Eighth | 37½ out |
| Sunday, August 17 |
| » Lost to Indians (60-59), 9-3 | Braves Field (2-9) | 41-76 | |
| » Starters: Willis Hudlin vs Hod Lisenbee | Eighth | 39 out |
| » Lost to Indians (61-59), 2-0 | Braves Field (2-10) | 41-77 | Lost 2 |
| » Starters: Clint Brown vs Danny MacFayden | Eighth | 39 out |
| Tuesday, August 19 |
| » Lost to Indians (62-59), 7-2 | Fenway Park (23-28) | 41-78 | Lost 3 |
| » Starters: Wes Ferrell vs Milt Gaston | Eighth | 40 out |
| » Lost to Indians (63-59), 7-3 | Fenway Park (23-29) | 41-79 | Lost 4 |
| » Starters: Roxie Lawson vs Jack Russell | Eighth | 40 out |
| Thursday, August 21 |
| » Defeated White Sox (46-74), 4-2 | Fenway Park (24-29) | 42-79 | |
| » Starters: Tommy Thomas vs Hod Lisenbee | Eighth | 40½ out |
| Friday, August 22 |
| » Lost to White Sox (47-74), 6-4 | Fenway Park (24-30) | 42-80 | |
| » Starters: Ted Lyons vs Danny MacFayden | Eighth | 40½ out |
| Sunday, August 24 |
| » Defeated White Sox (47-75), 2-0 | Braves Field (3-10) | 43-80 | |
| » Starters: Red Faber vs Milt Gaston | Eighth | 40½ out |
| » Lost to White Sox (48-75), 5-4 | Braves Field (3-11) | 43-81 | |
| » Starters: Pat Caraway vs Ed Durham | Eighth | 40½ out |
| Thursday, August 28 |
| » Defeated Athletics (86-44), 2-1 | Fenway Park (25-30) | 44-81 | |
| » Starters: George Earnshaw vs Hod Lisenbee | Eighth | 39½ out |
| Saturday, August 30 |
| » Lost to Athletics (87-44), 11-0 | Fenway Park (25-31) | 44-82 | |
| » Starters: Lefty Grove vs Milt Gaston | Eighth | 40½ out |
| Sunday, August 31 |
| » Lost to Athletics (88-44), 2-1 | Braves Field (3-12) | 44-83 | Lost 2 |
| » Starters: Bill Shores vs Danny MacFayden | Eighth | 41½ out |
| Monday, September 1 |
| » Lost to Senators (81-49), 2-1 | Griffith Stadium (2-8) | 44-84 | Lost 3 |
| » Starters: Hod Lisenbee vs General Crowder | Eighth | 42½ out |
| » Lost to Senators (82-49), 6-3 | Griffith Stadium (2-9) | 44-85 | Lost 4 |
| » Starters: Ed Durham vs Firpo Marberry | Eighth | 42½ out |
| Future Red Sox Dean Stone is born in Moline, IL. |
| Wednesday, September 3 |
| » Lost to Athletics (90-45), 11-4 | Shibe Park (1-7) | 44-86 | Lost 5 |
| » Starters: Milt Gaston vs Lefty Grove | Eighth | 43½ out |
| Thursday, September 4 |
| » Lost to Athletics (91-45), 8-7 | Shibe Park (1-8) | 44-87 | Lost 6 |
| » Starters: Danny MacFayden vs Bill Shores | Eighth | 44½ out |
| Friday, September 5 |
| » Lost to Athletics (92-45), 5-1 | Shibe Park (1-9) | 44-88 | Lost 7 |
| » Starters: Jack Russell vs George Earnshaw | Eighth | 45½ out |
| Saturday, September 6 |
| » Lost to Athletics (93-45), 3-1 | Shibe Park (1-10) | 44-89 | Lost 8 |
| » Starters: Hod Lisenbee vs Bill Shores | Eighth | 46½ out |
| Sunday, September 7 |
| » Defeated Yankees (76-59), 5-3 | Yankee Stadium (3-7) | 45-89 | |
| » Starters: Milt Gaston vs Herb Pennock | Eighth | 46 out |
| » Lost to Yankees (77-59), 5-2 | Yankee Stadium (3-8) | 45-90 | |
| » Starters: Ed Durham vs Roy Sherid | Eighth | 46 out |
| Tuesday, September 9 |
| » Lost to White Sox (54-83), 10-1 | Comiskey Park I (5-4) | 45-91 | Lost 2 |
| » Starters: Jack Russell vs Pat Caraway | Eighth | 47 out |
| Wednesday, September 10 |
| » Defeated White Sox (54-84), 6-2 | Comiskey Park I (6-4) | 46-91 | |
| » Starters: Danny MacFayden vs Red Faber | Eighth | 46 out |
| Thursday, September 11 |
| » Lost to White Sox (55-84), 4-3 | Comiskey Park I (6-5) | 46-92 | |
| » Starters: Hod Lisenbee vs Ted Lyons | Eighth | 46½ out |
| Friday, September 12 |
| » Lost to Browns (57-84), 5-4 | Sportsman's Park III (1-7) | 46-93 | Lost 2 |
| » Starters: Milt Gaston vs George Blaeholder | Eighth | 47 out |
| Saturday, September 13 |
| » Lost to Browns (58-84), 5-4 | Sportsman's Park III (1-8) | 46-94 | Lost 3 |
| » Starters: Jack Russell vs Rollie Stiles | Eighth | 48½ out |
| » Lost to Browns (59-84), 5-2 | Sportsman's Park III (1-9) | 46-95 | Lost 4 |
| » Starters: Ed Durham vs Rip Collins | Eighth | 48½ out |
| Monday, September 15 |
| » Lost to Browns (60-84), 3-1 | Sportsman's Park III (1-10) | 46-96 | Lost 5 |
| » Starters: Hod Lisenbee vs Lefty Stewart | Eighth | 49 out |
| » Defeated Browns (60-85), 2-1 | Sportsman's Park III (2-10) | 47-96 | |
| » Starters: Danny MacFayden vs Dick Coffman | Eighth | 49 out |
| Tuesday, September 16 |
| » Lost to Tigers (71-74), 7-5 | Tiger Stadium (3-6) | 47-97 | |
| » Starters: Milt Gaston vs Waite Hoyt | Eighth | 50½ out |
| Wednesday, September 17 |
| » Lost to Tigers (72-74), 9-7 | Tiger Stadium (3-7) | 47-98 | Lost 2 |
| » Starters: Ed Durham vs Earl Whitehill | Eighth | 50½ out |
| » Major-league debuts: Bob Kline (Red Sox) |
| Thursday, September 18 |
| » Defeated Tigers (72-75), 4-3 | Tiger Stadium (4-7) | 48-98 | |
| » Starters: Hod Lisenbee vs Tommy Bridges | Eighth | 50½ out |
| Friday, September 19 |
| » Lost to Indians (79-70), 7-5 | League Park II (2-7) | 48-99 | |
| » Starters: Danny MacFayden vs Mel Harder | Eighth | 51 out |
| Future Red Sox Bob Turley is born in Troy, IL. |
| Saturday, September 20 |
| » Defeated Indians (79-71), 10-3 | League Park II (3-7) | 49-99 | |
| » Starters: Milt Gaston vs Roxie Lawson | Eighth | 50 out |
| » Major-league debuts: Ralph Winegarner (Indians) |
| Sunday, September 21 |
| » Defeated Indians (79-72), 9-4 | League Park II (4-7) | 50-99 | Won 2 |
| » Starters: Jack Russell vs Willis Hudlin | Eighth | 49½ out |
| Future Red Sox Billy Muffett is born in Hammond, IN. |
| Wednesday, September 24 |
| » Defeated Senators (91-59), 6-3 | Fenway Park (26-31) | 51-99 | Won 3 |
| » Starters: General Crowder vs Hod Lisenbee | Eighth | 49 out |
| Thursday, September 25 |
| » Lost to Senators (92-59), 3-2 | Fenway Park (26-32) | 51-100 | |
| » Starters: Ad Liska vs Danny MacFayden | Eighth | 50 out |
| Former Red Sox Joe Wilhoit dies in Santa Barbara, CA at the age of 45. |
| Friday, September 26 |
| » Defeated Senators (92-60), 7-1 | Fenway Park (27-32) | 52-100 | |
| » Starters: Bump Hadley vs Milt Gaston | Eighth | 50 out |
| Saturday, September 27 |
| » Lost to Senators (93-60), 8-3 | Fenway Park (27-33) | 52-101 | |
| » Starters: Carl Fischer vs Ed Durham | Eighth | 50 out |
| Sunday, September 28 |
| » Lost to Yankees (86-68), 9-3 | Braves Field (3-13) | 52-102 | Lost 2 |
| » Starters: Babe Ruth vs Hod Lisenbee | Eighth | 50 out |
| Sunday, October 12 |
| Future Red Sox Joe Trimble is born in Providence, RI. |
| Tuesday, November 4 |
| Future Red Sox Guy Morton is born in Tuscaloosa, AL. |
| Monday, November 10 |
| Future Red Sox Gene Conley is born in Muskogee, OK. |
| Monday, December 15 |
| Future Red Sox Haywood Sullivan is born in Donalsonville, GA. |
Game information provided by Retrosheet (www.retrosheet.org) |
