| Friday, January 11 |
| Future White Sox Don Mossi is born in St. Helena, CA. |
| Tuesday, February 5 |
| Future White Sox Al Worthington is born in Birmingham, AL. |
| Thursday, March 7 |
| Future White Sox Red Wilson is born in Milwaukee, WI. |
| Tuesday, April 16 |
| » Lost to Browns (1-0), 3-1 | Sportsman's Park III (0-1) | 0-1 | |
| » Starters: Tommy Thomas vs Dolly Gray | Third | 1 out |
| Wednesday, April 17 |
| » Lost to Browns (2-0), 5-3 | Sportsman's Park III (0-2) | 0-2 | Lost 2 |
| » Starters: Grady Adkins vs Alvin Crowder | Sixth | 2 out |
| Thursday, April 18 |
| » Lost to Browns (3-0), 4-1 | Sportsman's Park III (0-3) | 0-3 | Lost 3 |
| » Starters: Ted Lyons vs Jack Ogden | Eighth | 3 out |
| Friday, April 19 |
| » Defeated Browns (3-1), 5-4 | Sportsman's Park III (1-3) | 1-3 | |
| » Starters: Red Faber vs Dick Coffman | Fifth | 2 out |
| » Major-league debuts: Rick Ferrell (Browns) |
| Sunday, April 21 |
| » Major-league debuts: Chad Kimsey (Browns) |
| Monday, April 22 |
| » Defeated Indians (3-2), 10-0 | League Park II (1-0) | 2-3 | Won 2 |
| » Starters: Tommy Thomas vs Joe Shaute | Sixth | 1½ out |
| Tuesday, April 23 |
| » Lost to Indians (4-2), 5-4 | League Park II (1-1) | 2-4 | |
| » Starters: Grady Adkins vs Jake Miller | Seventh | 2 out |
| Thursday, April 25 |
| » Lost to Browns (6-3), 3-2 | Comiskey Park I (0-1) | 2-5 | Lost 2 |
| » Starters: Dolly Gray vs Ted Lyons | Eighth | 3 out |
| Friday, April 26 |
| » Lost to Browns (7-3), 7-3 | Comiskey Park I (0-2) | 2-6 | Lost 3 |
| » Starters: Jack Ogden vs Red Faber | Seventh | 3½ out |
| Saturday, April 27 |
| » Defeated Indians (5-5), 7-1 | Comiskey Park I (1-2) | 3-6 | |
| » Starters: Joe Shaute vs Tommy Thomas | Eighth | 3 out |
| Sunday, April 28 |
| » Defeated Indians (5-6), 2-1 | Comiskey Park I (2-2) | 4-6 | Won 2 |
| » Starters: Jake Miller vs Grady Adkins | Sixth | 3 out |
| Monday, April 29 |
| » Defeated Indians (5-7), 13-4 | Comiskey Park I (3-2) | 5-6 | Won 3 |
| » Starters: Johnny Miljus vs Ted Lyons | Fourth | 2½ out |
| Tuesday, April 30 |
| » Defeated Indians (5-8), 8-4 | Comiskey Park I (4-2) | 6-6 | Won 4 |
| » Starters: Willis Hudlin vs Bob Weiland | Fourth | 3 out |
| Friday, May 3 |
| » Lost to Tigers (7-9), 6-1 | Comiskey Park I (4-3) | 6-7 | |
| » Starters: George Uhle vs Tommy Thomas | Fourth | 4 out |
| Saturday, May 4 |
| » Lost to Yankees (7-4), 11-9 | Comiskey Park I (4-4) | 6-8 | Lost 2 |
| » Starters: Waite Hoyt vs Red Faber | Fifth | 4½ out |
| Sunday, May 5 |
| » Lost to Yankees (8-4), 8-3 | Comiskey Park I (4-5) | 6-9 | Lost 3 |
| » Starters: George Pipgras vs Grady Adkins | Sixth | 4½ out |
| Monday, May 6 |
| » Lost to Yankees (9-4), 7-6 | Comiskey Park I (4-6) | 6-10 | Lost 4 |
| » Starters: Fred Heimach vs Bob Weiland | Sixth | 5 out |
| Tuesday, May 7 |
| » Defeated Athletics (10-5), 4-2 | Comiskey Park I (5-6) | 7-10 | |
| » Starters: Lefty Grove vs Tommy Thomas | Fifth | 4½ out |
| Wednesday, May 8 |
| » Lost to Athletics (11-5), 5-4 | Comiskey Park I (5-7) | 7-11 | |
| » Starters: Jack Quinn vs Red Faber | Sixth | 5½ out |
| Thursday, May 9 |
| » Lost to Athletics (12-5), 9-2 | Comiskey Park I (5-8) | 7-12 | Lost 2 |
| » Starters: George Earnshaw vs Grady Adkins | Sixth | 6½ out |
| Friday, May 10 |
| » Lost to Senators (6-11), 4-2 | Comiskey Park I (5-9) | 7-13 | Lost 3 |
| » Starters: Garland Braxton vs Bob Weiland | Seventh | 7½ out |
| Saturday, May 11 |
| » Lost to Senators (7-11), 9-2 | Comiskey Park I (5-10) | 7-14 | Lost 4 |
| » Starters: Sam Jones vs Tommy Thomas | Seventh | 7½ out |
| Sunday, May 12 |
| » Defeated Senators (7-12), 3-2 | Comiskey Park I (6-10) | 8-14 | |
| » Starters: Bobby Burke vs Red Faber | Sixth | 6½ out |
| Monday, May 13 |
| » Lost to Red Sox (7-14), 2-1 | Comiskey Park I (6-11) | 8-15 | |
| » Starters: Danny MacFayden vs Grady Adkins | Sixth | 6½ out |
| Tuesday, May 14 |
| » Defeated Red Sox (7-15), 6-2 | Comiskey Park I (7-11) | 9-15 | |
| » Starters: Jack Russell vs Bob Weiland | Seventh | 6½ out |
| Wednesday, May 15 |
| » Defeated Red Sox (7-16), 8-4 | Comiskey Park I (8-11) | 10-15 | Won 2 |
| » Starters: Red Ruffing vs Ted Lyons | Sixth | 5½ out |
| Thursday, May 16 |
| » Lost to Tigers (17-12), 4-3 | Tiger Stadium (0-1) | 10-16 | |
| » Starters: Tommy Thomas vs Ownie Carroll | Sixth | 6 out |
| Friday, May 17 |
| » Defeated Tigers (17-13), 6-2 | Tiger Stadium (1-1) | 11-16 | |
| » Starters: Red Faber vs Earl Whitehill | Sixth | 6 out |
| Saturday, May 18 |
| » Lost to Tigers (18-13), 11-4 | Tiger Stadium (1-2) | 11-17 | |
| » Starters: Grady Adkins vs George Uhle | Sixth | 7½ out |
| Sunday, May 19 |
| » Defeated Tigers (18-14), 10-3 | Tiger Stadium (2-2) | 12-17 | |
| » Starters: Ted Lyons vs Vic Sorrell | Sixth | 7½ out |
| Monday, May 20 |
| » Lost to Browns (17-11), 6-3 | Sportsman's Park III (1-4) | 12-18 | |
| » Starters: Tommy Thomas vs Dolly Gray | Sixth | 8½ out |
| Tuesday, May 21 |
| » Lost to Browns (18-11), 7-1 | Sportsman's Park III (1-5) | 12-19 | Lost 2 |
| » Starters: Ted Blankenship vs Alvin Crowder | Sixth | 9 out |
| Wednesday, May 22 |
| » Lost to Browns (19-11), 7-3 | Sportsman's Park III (1-6) | 12-20 | Lost 3 |
| » Starters: Red Faber vs Rip Collins | Sixth | 10 out |
| Friday, May 24 |
| » Lost to Tigers (20-15), 6-5 | Comiskey Park I (8-12) | 12-21 | Lost 4 |
| » Starters: George Uhle vs Ted Lyons | Sixth | 12 out |
| Saturday, May 25 |
| » Lost to Tigers (21-15), 5-2 | Comiskey Park I (8-13) | 12-22 | Lost 5 |
| » Starters: Vic Sorrell vs Tommy Thomas | Sixth | 13½ out |
| » Lost to Tigers (22-15), 4-3 | Comiskey Park I (8-14) | 12-23 | Lost 6 |
| » Starters: George Smith vs Grady Adkins | Sixth | 13½ out |
| Sunday, May 26 |
| » Defeated Tigers (22-16), 2-0 | Comiskey Park I (9-14) | 13-23 | |
| » Starters: Ownie Carroll vs Red Faber | Sixth | 13½ out |
| Monday, May 27 |
| » Defeated Tigers (22-17), 7-4 | Comiskey Park I (10-14) | 14-23 | Won 2 |
| » Starters: Lil Stoner vs Grady Adkins | Sixth | 12½ out |
| » Defeated Tigers (22-18), 6-5 | Comiskey Park I (11-14) | 15-23 | Won 3 |
| » Starters: Earl Whitehill vs Ed Walsh | Sixth | 12½ out |
| Tuesday, May 28 |
| » Lost to Indians (17-19), 5-2 | Comiskey Park I (11-15) | 15-24 | |
| » Starters: Joe Shaute vs Dan Dugan | Sixth | 12½ out |
| Wednesday, May 29 |
| » Lost to Indians (18-19), 11-1 | Comiskey Park I (11-16) | 15-25 | Lost 2 |
| » Starters: Jimmy Zinn vs Tommy Thomas | Sixth | 13½ out |
| Thursday, May 30 |
| » Lost to Indians (19-19), 6-5 | Comiskey Park I (11-17) | 15-26 | Lost 3 |
| » Starters: Willis Hudlin vs Ted Lyons | Sixth | 14½ out |
| » Defeated Indians (19-20), 3-2 | Comiskey Park I (12-17) | 16-26 | |
| » Starters: Ken Holloway vs Red Faber | Sixth | 14½ out |
| Saturday, June 1 |
| » Lost to Yankees (21-16), 8-1 | Yankee Stadium (0-1) | 16-27 | |
| » Starters: Dan Dugan vs Waite Hoyt | Sixth | 16 out |
| Sunday, June 2 |
| » Lost to Yankees (22-16), 6-1 | Yankee Stadium (0-2) | 16-28 | Lost 2 |
| » Starters: Ed Walsh vs George Pipgras | Seventh | 16½ out |
| Monday, June 3 |
| » Lost to Yankees (23-16), 1-0 | Yankee Stadium (0-3) | 16-29 | Lost 3 |
| » Starters: Ted Lyons vs Ed Wells | Seventh | 17½ out |
| Tuesday, June 4 |
| » Lost to Yankees (24-16), 4-2 | Yankee Stadium (0-4) | 16-30 | Lost 4 |
| » Starters: Red Faber vs Hank Johnson | Seventh | 17½ out |
| Wednesday, June 5 |
| » Lost to Red Sox (13-29), 17-2 | Fenway Park (0-1) | 16-31 | Lost 5 |
| » Starters: Tommy Thomas vs Danny MacFayden | Seventh | 18½ out |
| Thursday, June 6 |
| » Defeated Red Sox (13-30), 9-5 | Fenway Park (1-1) | 17-31 | |
| » Starters: Grady Adkins vs Ed Morris | Seventh | 18½ out |
| Saturday, June 8 |
| » Defeated Red Sox (13-31), 7-2 | Fenway Park (2-1) | 18-31 | Won 2 |
| » Starters: Ted Lyons vs Jack Russell | Seventh | 18 out |
| » Lost to Red Sox (14-31), 4-1 | Fenway Park (2-2) | 18-32 | |
| » Starters: Red Faber vs Milt Gaston | Seventh | 18 out |
| Monday, June 10 |
| » Lost to Athletics (34-11), 3-1 | Shibe Park (0-1) | 18-33 | Lost 2 |
| » Starters: Grady Adkins vs Lefty Grove | Seventh | 19 out |
| Tuesday, June 11 |
| » Lost to Athletics (35-11), 14-3 | Shibe Park (0-2) | 18-34 | Lost 3 |
| » Starters: Ed Walsh vs George Earnshaw | Seventh | 20 out |
| Wednesday, June 12 |
| » Lost to Athletics (36-11), 7-3 | Shibe Park (0-3) | 18-35 | Lost 4 |
| » Starters: Ted Lyons vs Rube Walberg | Seventh | 21 out |
| Thursday, June 13 |
| » Defeated Senators (18-30), 11-8 | Griffith Stadium (1-0) | 19-35 | |
| » Starters: Red Faber vs Garland Braxton | Seventh | 21 out |
| Friday, June 14 |
| » Lost to Senators (19-30), 4-1 | Griffith Stadium (1-1) | 19-36 | |
| » Starters: Grady Adkins vs Bump Hadley | Seventh | 22 out |
| Saturday, June 15 |
| » Defeated Senators (19-31), 5-1 | Griffith Stadium (2-1) | 20-36 | |
| » Starters: Ed Walsh vs Ad Liska | Seventh | 22 out |
| Sunday, June 16 |
| » Lost to Senators (20-31), 5-3 | Griffith Stadium (2-2) | 20-37 | |
| » Starters: Ted Lyons vs Firpo Marberry | Seventh | 22 out |
| Monday, June 17 |
| » Defeated Athletics (39-13), 6-4 | Shibe Park (1-3) | 21-37 | |
| » Starters: Red Faber vs Jack Quinn | Seventh | 21 out |
| Wednesday, June 19 |
| » Lost to Browns (33-23), 5-2 | Sportsman's Park III (1-7) | 21-38 | |
| » Starters: Grady Adkins vs Dolly Gray | Seventh | 22 out |
| Future White Sox Don Ferrarese is born in Oakland, CA. |
| Thursday, June 20 |
| » Defeated Browns (33-24), 5-3 | Sportsman's Park III (2-7) | 22-38 | |
| » Starters: Ed Walsh vs Alvin Crowder | Seventh | 21½ out |
| » Major-league debuts: Red Badgro (Browns) |
| Saturday, June 22 |
| » Lost to Browns (34-24), 11-3 | Sportsman's Park III (2-8) | 22-39 | |
| » Starters: Ted Lyons vs Rip Collins | Seventh | 22 out |
| Sunday, June 23 |
| » Lost to Browns (35-24), 6-5 | Sportsman's Park III (2-9) | 22-40 | Lost 2 |
| » Starters: Grady Adkins vs Dolly Gray | Sixth | 23 out |
| Monday, June 24 |
| » Lost to Tigers (35-30), 13-4 | Tiger Stadium (2-3) | 22-41 | Lost 3 |
| » Starters: Red Faber vs Emil Yde | Seventh | 24 out |
| Tuesday, June 25 |
| » Lost to Tigers (36-30), 14-2 | Tiger Stadium (2-4) | 22-42 | Lost 4 |
| » Starters: Ed Walsh vs Vic Sorrell | Seventh | 25½ out |
| Wednesday, June 26 |
| » Defeated Tigers (36-31), 5-3 | Tiger Stadium (3-4) | 23-42 | |
| » Starters: Ted Lyons vs Augie Prudhomme | Seventh | 25½ out |
| Thursday, June 27 |
| » Lost to Browns (38-26), 4-1 | Comiskey Park I (12-18) | 23-43 | |
| » Starters: Dolly Gray vs Tommy Thomas | Seventh | 26½ out |
| Future White Sox Dick Marlowe is born in Hickory, NC. |
| Friday, June 28 |
| » Lost to Browns (39-26), 7-2 | Comiskey Park I (12-19) | 23-44 | Lost 2 |
| » Starters: Alvin Crowder vs Grady Adkins | Seventh | 27 out |
| Saturday, June 29 |
| » Lost to Browns (40-26), 2-0 | Comiskey Park I (12-20) | 23-45 | Lost 3 |
| » Starters: George Blaeholder vs Red Faber | Seventh | 27½ out |
| » Lost to Browns (41-26), 12-4 | Comiskey Park I (12-21) | 23-46 | Lost 4 |
| » Starters: Lefty Stewart vs Ed Walsh | Seventh | 27½ out |
| Tuesday, July 2 |
| » Lost to Indians (32-34), 4-3 | League Park II (1-2) | 23-47 | Lost 5 |
| » Starters: Tommy Thomas vs Joe Shaute | Seventh | 29 out |
| » Lost to Indians (33-34), 5-4 | League Park II (1-3) | 23-48 | Lost 6 |
| » Starters: Bob Weiland vs Willis Hudlin | Seventh | 29 out |
| Future White Sox Chuck Stobbs is born in Wheeling, WV. |
| Wednesday, July 3 |
| » Defeated Indians (33-35), 6-3 | League Park II (2-3) | 24-48 | |
| » Starters: Ed Walsh vs Wes Ferrell | Seventh | 29 out |
| Thursday, July 4 |
| » Defeated Indians (33-36), 9-2 | League Park II (3-3) | 25-48 | Won 2 |
| » Starters: Red Faber vs Jake Miller | Seventh | 30 out |
| » Lost to Indians (34-36), 12-5 | League Park II (3-4) | 25-49 | |
| » Starters: Ted Lyons vs Johnny Miljus | Seventh | 30 out |
| Friday, July 5 |
| » Lost to Indians (35-36), 11-10 | League Park II (3-5) | 25-50 | Lost 2 |
| » Starters: Bob Weiland vs Jimmy Zinn | Seventh | 30½ out |
| Saturday, July 6 |
| » Defeated Athletics (53-18), 5-4 | Comiskey Park I (13-21) | 26-50 | |
| » Starters: Rube Walberg vs Tommy Thomas | Seventh | 29½ out |
| Sunday, July 7 |
| » Defeated Athletics (53-19), 9-3 | Comiskey Park I (14-21) | 27-50 | Won 2 |
| » Starters: George Earnshaw vs Ted Lyons | Seventh | 28½ out |
| Monday, July 8 |
| » Lost to Athletics (54-19), 8-2 | Comiskey Park I (14-22) | 27-51 | |
| » Starters: Lefty Grove vs Hal McKain | Seventh | 29½ out |
| Tuesday, July 9 |
| » Defeated Athletics (54-20), 6-4 | Comiskey Park I (15-22) | 28-51 | |
| » Starters: Jack Quinn vs Red Faber | Seventh | 28½ out |
| Wednesday, July 10 |
| » Defeated Yankees (46-28), 6-3 | Comiskey Park I (16-22) | 29-51 | Won 2 |
| » Starters: Fred Heimach vs Tommy Thomas | Seventh | 28 out |
| Friday, July 12 |
| » Lost to Yankees (47-28), 12-2 | Comiskey Park I (16-23) | 29-52 | |
| » Starters: Herb Pennock vs Ted Lyons | Seventh | 29½ out |
| Saturday, July 13 |
| » Lost to Yankees (48-28), 4-2 | Comiskey Park I (16-24) | 29-53 | Lost 2 |
| » Starters: Tom Zachary vs Red Faber | Seventh | 30½ out |
| » Lost to Yankees (49-28), 6-5 | Comiskey Park I (16-25) | 29-54 | Lost 3 |
| » Starters: Waite Hoyt vs Hal McKain | Seventh | 30½ out |
| Sunday, July 14 |
| » Lost to Senators (30-47), 7-1 | Comiskey Park I (16-26) | 29-55 | Lost 4 |
| » Starters: Garland Braxton vs Tommy Thomas | Seventh | 31½ out |
| Monday, July 15 |
| » Defeated Senators (30-48), 4-2 | Comiskey Park I (17-26) | 30-55 | |
| » Starters: Firpo Marberry vs Ed Walsh | Seventh | 31 out |
| Tuesday, July 16 |
| » Defeated Senators (30-49), 6-5 | Comiskey Park I (18-26) | 31-55 | Won 2 |
| » Starters: Myles Thomas vs Bob Weiland | Seventh | 31 out |
| Wednesday, July 17 |
| » Lost to Senators (31-49), 6-2 | Comiskey Park I (18-27) | 31-56 | |
| » Starters: Bobby Burke vs Ted Lyons | Seventh | 31 out |
| Thursday, July 18 |
| » Defeated Red Sox (26-60), 2-1 | Comiskey Park I (19-27) | 32-56 | |
| » Starters: Danny MacFayden vs Red Faber | Seventh | 31 out |
| Friday, July 19 |
| » Defeated Red Sox (26-61), 2-1 | Comiskey Park I (20-27) | 33-56 | Won 2 |
| » Starters: Jack Russell vs Tommy Thomas | Seventh | 31 out |
| Saturday, July 20 |
| » Defeated Red Sox (26-62), 4-3 | Comiskey Park I (21-27) | 34-56 | Won 3 |
| » Starters: Milt Gaston vs Ed Walsh | Seventh | 31 out |
| Sunday, July 21 |
| » Defeated Red Sox (26-63), 10-0 | Comiskey Park I (22-27) | 35-56 | Won 4 |
| » Starters: Red Ruffing vs Ted Lyons | Seventh | 31 out |
| Tuesday, July 23 |
| » Defeated Senators (34-52), 3-2 | Griffith Stadium (3-2) | 36-56 | Won 5 |
| » Starters: Red Faber vs Garland Braxton | Seventh | 30½ out |
| Wednesday, July 24 |
| » Lost to Senators (35-52), 3-2 | Griffith Stadium (3-3) | 36-57 | |
| » Starters: Tommy Thomas vs Bobby Burke | Seventh | 31½ out |
| Thursday, July 25 |
| » Defeated Senators (35-53), 3-1 | Griffith Stadium (4-3) | 37-57 | |
| » Starters: Ed Walsh vs Firpo Marberry | Seventh | 31½ out |
| Friday, July 26 |
| » Lost to Athletics (69-25), 3-1 | Shibe Park (1-4) | 37-58 | |
| » Starters: Ted Lyons vs Howard Ehmke | Seventh | 32½ out |
| Saturday, July 27 |
| » Lost to Athletics (70-25), 8-1 | Shibe Park (1-5) | 37-59 | Lost 2 |
| » Starters: Hal McKain vs Rube Walberg | Seventh | 33½ out |
| Monday, July 29 |
| » Defeated Athletics (70-26), 8-6 | Shibe Park (2-5) | 38-59 | |
| » Starters: Red Faber vs George Earnshaw | Sixth | 32½ out |
| Tuesday, July 30 |
| » Lost to Yankees (59-33), 7-3 | Yankee Stadium (0-5) | 38-60 | |
| » Starters: Tommy Thomas vs Herb Pennock | Seventh | 33½ out |
| Wednesday, July 31 |
| » Lost to Yankees (60-33), 16-2 | Yankee Stadium (0-6) | 38-61 | Lost 2 |
| » Starters: Ed Walsh vs Ed Wells | Seventh | 34½ out |
| Thursday, August 1 |
| » Defeated Yankees (60-34), 3-2 | Yankee Stadium (1-6) | 39-61 | |
| » Starters: Ted Lyons vs Roy Sherid | Seventh | 34½ out |
| Friday, August 2 |
| » Lost to Red Sox (30-69), 3-2 | Fenway Park (2-3) | 39-62 | |
| » Starters: Red Faber vs Jack Russell | Seventh | 35½ out |
| Saturday, August 3 |
| » Defeated Red Sox (30-70), 15-4 | Fenway Park (3-3) | 40-62 | |
| » Starters: Tommy Thomas vs Red Ruffing | Seventh | 35 out |
| Sunday, August 4 |
| » Lost to Red Sox (31-70), 8-0 | Braves Field (0-1) | 40-63 | |
| » Starters: Ed Walsh vs Ed Morris | Seventh | 35½ out |
| Thursday, August 8 |
| » Defeated Browns (55-49), 5-4 | Comiskey Park I (23-27) | 41-63 | |
| » Starters: Dolly Gray vs Tommy Thomas | Sixth | 34 out |
| » Defeated Browns (55-50), 6-2 | Comiskey Park I (24-27) | 42-63 | Won 2 |
| » Starters: George Blaeholder vs Red Faber | Sixth | 34 out |
| Friday, August 9 |
| » Lost to Browns (56-50), 9-4 | Comiskey Park I (24-28) | 42-64 | |
| » Starters: Rip Collins vs Ted Lyons | Seventh | 34½ out |
| Saturday, August 10 |
| » Lost to Red Sox (32-72), 10-7 | Comiskey Park I (24-29) | 42-65 | Lost 2 |
| » Starters: Jack Russell vs Ed Walsh | Seventh | 35½ out |
| Sunday, August 11 |
| » Defeated Red Sox (32-73), 6-3 | Comiskey Park I (25-29) | 43-65 | |
| » Starters: Red Ruffing vs Tommy Thomas | Seventh | 34½ out |
| Monday, August 12 |
| » Lost to Red Sox (33-73), 3-0 | Comiskey Park I (25-30) | 43-66 | |
| » Starters: Danny MacFayden vs Ted Lyons | Seventh | 35½ out |
| Tuesday, August 13 |
| » Lost to Red Sox (34-73), 8-2 | Comiskey Park I (25-31) | 43-67 | Lost 2 |
| » Starters: Ed Morris vs Bob Weiland | Seventh | 36½ out |
| Wednesday, August 14 |
| » Lost to Senators (46-61), 11-3 | Comiskey Park I (25-32) | 43-68 | Lost 3 |
| » Starters: Myles Thomas vs Ed Walsh | Seventh | 37½ out |
| Thursday, August 15 |
| » Lost to Senators (47-61), 9-4 | Comiskey Park I (25-33) | 43-69 | Lost 4 |
| » Starters: Firpo Marberry vs Red Faber | Seventh | 38 out |
| Friday, August 16 |
| » Defeated Senators (47-62), 8-6 | Comiskey Park I (26-33) | 44-69 | |
| » Starters: Bobby Burke vs Tommy Thomas | Seventh | 38 out |
| Saturday, August 17 |
| » Lost to Senators (48-62), 5-2 | Comiskey Park I (26-34) | 44-70 | |
| » Starters: Lloyd Brown vs Bob Weiland | Seventh | 38 out |
| Sunday, August 18 |
| » Defeated Yankees (67-44), 3-2 | Comiskey Park I (27-34) | 45-70 | |
| » Starters: Herb Pennock vs Ted Lyons | Seventh | 37 out |
| Monday, August 19 |
| » Lost to Yankees (68-44), 3-2 | Comiskey Park I (27-35) | 45-71 | |
| » Starters: Roy Sherid vs Hal McKain | Seventh | 38 out |
| Tuesday, August 20 |
| » Lost to Yankees (69-44), 5-4 | Comiskey Park I (27-36) | 45-72 | Lost 2 |
| » Starters: Tom Zachary vs Red Faber | Seventh | 38 out |
| Wednesday, August 21 |
| » Defeated Yankees (69-45), 4-3 | Comiskey Park I (28-36) | 46-72 | |
| » Starters: Ed Wells vs Tommy Thomas | Seventh | 37 out |
| Thursday, August 22 |
| » Defeated Athletics (83-36), 4-3 | Comiskey Park I (29-36) | 47-72 | Won 2 |
| » Starters: Lefty Grove vs Ted Lyons | Seventh | 36 out |
| Friday, August 23 |
| » Defeated Athletics (83-37), 3-1 | Comiskey Park I (30-36) | 48-72 | Won 3 |
| » Starters: Jack Quinn vs Hal McKain | Seventh | 35 out |
| Saturday, August 24 |
| » Lost to Athletics (84-37), 5-2 | Comiskey Park I (30-37) | 48-73 | |
| » Starters: Rube Walberg vs Red Faber | Seventh | 36 out |
| Sunday, August 25 |
| » Defeated Athletics (84-38), 3-0 | Comiskey Park I (31-37) | 49-73 | |
| » Starters: Bill Shores vs Tommy Thomas | Seventh | 35 out |
| Thursday, August 29 |
| » Defeated Indians (63-59), 2-1 | Comiskey Park I (32-37) | 50-73 | Won 2 |
| » Starters: Willis Hudlin vs Ted Lyons | Seventh | 35 out |
| Saturday, August 31 |
| » Lost to Indians (64-59), 8-5 | Comiskey Park I (32-38) | 50-74 | |
| » Starters: Wes Ferrell vs Hal McKain | Seventh | 35½ out |
| Sunday, September 1 |
| » Lost to Indians (65-59), 5-0 | Comiskey Park I (32-39) | 50-75 | Lost 2 |
| » Starters: Ken Holloway vs Tommy Thomas | Seventh | 35½ out |
| Monday, September 2 |
| » Lost to Tigers (60-66), 10-8 | Tiger Stadium (3-5) | 50-76 | Lost 3 |
| » Starters: Red Faber vs Ownie Carroll | Seventh | 36½ out |
| » Defeated Tigers (60-67), 8-2 | Tiger Stadium (4-5) | 51-76 | |
| » Starters: Ted Lyons vs Vic Sorrell | Seventh | 36½ out |
| Wednesday, September 4 |
| » Lost to Browns (67-61), 7-2 | Comiskey Park I (32-40) | 51-77 | |
| » Starters: Jack Ogden vs Hal McKain | Seventh | 37½ out |
| Saturday, September 7 |
| » Lost to Senators (60-70), 2-1 | Griffith Stadium (4-4) | 51-78 | Lost 2 |
| » Starters: Tommy Thomas vs Firpo Marberry | Seventh | 38 out |
| Sunday, September 8 |
| » Defeated Senators (60-71), 4-3 | Griffith Stadium (5-4) | 52-78 | |
| » Starters: Red Faber vs Myles Thomas | Seventh | 37½ out |
| Monday, September 9 |
| » Defeated Senators (60-72), 6-4 | Griffith Stadium (6-4) | 53-78 | Won 2 |
| » Starters: Ed Walsh vs Sam Jones | Seventh | 37 out |
| Wednesday, September 11 |
| » Lost to Athletics (93-42), 7-4 | Shibe Park (2-6) | 53-79 | |
| » Starters: Ted Lyons vs Lefty Grove | Seventh | 38½ out |
| Thursday, September 12 |
| » Lost to Athletics (94-42), 4-3 | Shibe Park (2-7) | 53-80 | Lost 2 |
| » Starters: Tommy Thomas vs Rube Walberg | Seventh | 39½ out |
| Friday, September 13 |
| » Lost to Athletics (95-42), 5-2 | Shibe Park (2-8) | 53-81 | Lost 3 |
| » Starters: Ed Walsh vs Howard Ehmke | Seventh | 40½ out |
| Saturday, September 14 |
| » Lost to Athletics (96-42), 5-0 | Shibe Park (2-9) | 53-82 | Lost 4 |
| » Starters: Red Faber vs George Earnshaw | Seventh | 41½ out |
| Sunday, September 15 |
| » Lost to Red Sox (51-89), 5-4 | Braves Field (0-2) | 53-83 | Lost 5 |
| » Starters: Ted Lyons vs Danny MacFayden | Seventh | 41½ out |
| » Defeated Red Sox (51-90), 3-2 | Braves Field (1-2) | 54-83 | |
| » Starters: Hal McKain vs Jack Russell | Seventh | 41½ out |
| Monday, September 16 |
| » Lost to Red Sox (52-90), 4-3 | Fenway Park (3-4) | 54-84 | |
| » Starters: Tommy Thomas vs Red Ruffing | Seventh | 41½ out |
| Tuesday, September 17 |
| » Lost to Red Sox (53-90), 6-4 | Fenway Park (3-5) | 54-85 | Lost 2 |
| » Starters: Ed Walsh vs Ed Carroll | Seventh | 42 out |
| Wednesday, September 18 |
| » Major-league debuts: Doc Cramer (Athletics) |
| Thursday, September 19 |
| » Defeated Yankees (82-61), 7-0 | Yankee Stadium (2-6) | 55-85 | |
| » Starters: Hal McKain vs George Pipgras | Seventh | 42 out |
| Saturday, September 21 |
| » Lost to Yankees (83-61), 8-5 | Yankee Stadium (2-7) | 55-86 | |
| » Starters: Ted Lyons vs Ed Wells | Sixth | 43½ out |
| Sunday, September 22 |
| » Defeated Yankees (83-62), 7-4 | Yankee Stadium (3-7) | 56-86 | |
| » Starters: Red Faber vs Herb Pennock | Seventh | 43 out |
| » Lost to Yankees (84-62), 3-1 | Yankee Stadium (3-8) | 56-87 | |
| » Starters: Tommy Thomas vs Roy Sherid | Seventh | 43 out |
| Monday, September 23 |
| » Lost to Senators (69-77), 7-6 | Griffith Stadium (6-5) | 56-88 | Lost 2 |
| » Starters: Hal McKain vs Lloyd Brown | Seventh | 43½ out |
| Tuesday, September 24 |
| » Lost to Indians (77-68), 7-4 | League Park II (3-6) | 56-89 | Lost 3 |
| » Starters: Ted Lyons vs Willis Hudlin | Seventh | 44 out |
| Wednesday, September 25 |
| » Lost to Indians (78-68), 9-7 | League Park II (3-7) | 56-90 | Lost 4 |
| » Starters: Ed Walsh vs Ken Holloway | Seventh | 44½ out |
| Saturday, September 28 |
| » Lost to Tigers (68-81), 11-10 | Tiger Stadium (4-6) | 56-91 | Lost 5 |
| » Starters: Tommy Thomas vs Chief Hogsett | Seventh | 46 out |
| Sunday, September 29 |
| » Lost to Tigers (69-81), 9-8 | Tiger Stadium (4-7) | 56-92 | Lost 6 |
| » Starters: Red Faber vs Whit Wyatt | Seventh | 46 out |
| Thursday, October 3 |
| » Defeated Tigers (69-82), 3-1 | Comiskey Park I (33-40) | 57-92 | |
| » Starters: Chief Hogsett vs Ted Lyons | Seventh | 45½ out |
| Friday, October 4 |
| » Defeated Tigers (69-83), 14-6 | Comiskey Park I (34-40) | 58-92 | Won 2 |
| » Starters: Art Herring vs Dutch Henry | Seventh | 45 out |
| Saturday, October 5 |
| » Lost to Tigers (70-83), 6-3 | Comiskey Park I (34-41) | 58-93 | |
| » Starters: Earl Whitehill vs Jerry Byrne | Seventh | 46 out |
| Sunday, October 6 |
| » Defeated Tigers (70-84), 8-7 | Comiskey Park I (35-41) | 59-93 | |
| » Starters: Whit Wyatt vs Ed Walsh | Seventh | 46 out |
| Thursday, October 24 |
| Future White Sox Jim Brosnan is born in Cincinnati, OH. |
| Sunday, December 15 |
| Future White Sox Ray Herbert is born in Detroit, MI. |
Game information provided by Retrosheet (www.retrosheet.org) |