| Friday, January 11 |
| Future Tiger Don Mossi is born in St. Helena, CA. |
| Thursday, January 31 |
| Future Tiger Duke Maas is born in Utica, MI. |
| Thursday, March 7 |
| Future Tiger Red Wilson is born in Milwaukee, WI. |
| Tuesday, April 16 |
| » Lost to Indians (1-0), 5-4 | League Park II (0-1) | 0-1 | |
| » Starters: Earl Whitehill vs Joe Shaute | Third | 1 out |
| » Major-league debuts: Earl Averill (Indians) Dale Alexander (Tigers) |
| Wednesday, April 17 |
| » Defeated Indians (1-1), 15-3 | League Park II (1-1) | 1-1 | |
| » Starters: George Uhle vs Ken Holloway | Fourth | 1 out |
| Thursday, April 18 |
| » Lost to Indians (2-1), 8-4 | League Park II (1-2) | 1-2 | |
| » Starters: Ownie Carroll vs Johnny Miljus | Fifth | 2 out |
| » Major-league debuts: Frank Barnes and Roy Johnson (Tigers) |
| Friday, April 19 |
| » Lost to Indians (3-1), 7-4 | League Park II (1-3) | 1-3 | Lost 2 |
| » Starters: Vic Sorrell vs Willis Hudlin | Fifth | 2 out |
| Saturday, April 20 |
| » Lost to Browns (4-1), 9-4 | Sportsman's Park III (0-1) | 1-4 | Lost 3 |
| » Starters: Lil Stoner vs Dolly Gray | Seventh | 2½ out |
| Sunday, April 21 |
| » Defeated Browns (4-2), 16-9 | Sportsman's Park III (1-1) | 2-4 | |
| » Starters: Earl Whitehill vs Alvin Crowder | Fifth | 2 out |
| » Major-league debuts: Chad Kimsey (Browns) |
| Monday, April 22 |
| » Defeated Browns (4-3), 1-0 | Sportsman's Park III (2-1) | 3-4 | Won 2 |
| » Starters: George Uhle vs Jack Ogden | Fifth | 1½ out |
| Tuesday, April 23 |
| » Lost to Browns (5-3), 11-5 | Sportsman's Park III (2-2) | 3-5 | |
| » Starters: Ownie Carroll vs Alvin Crowder | Sixth | 2 out |
| Wednesday, April 24 |
| » Defeated Indians (4-3), 7-6 | Tiger Stadium (1-0) | 4-5 | |
| » Starters: Johnny Miljus vs Vic Sorrell | Fifth | 1½ out |
| Thursday, April 25 |
| » Defeated Indians (4-4), 5-0 | Tiger Stadium (2-0) | 5-5 | Won 2 |
| » Starters: Willis Hudlin vs Emil Yde | Fifth | 1½ out |
| Friday, April 26 |
| » Lost to Indians (5-4), 11-5 | Tiger Stadium (2-1) | 5-6 | |
| » Starters: Wes Ferrell vs Earl Whitehill | Fifth | 2 out |
| Saturday, April 27 |
| » Defeated Browns (7-4), 10-1 | Tiger Stadium (3-1) | 6-6 | |
| » Starters: George Blaeholder vs George Uhle | Fifth | 1½ out |
| Sunday, April 28 |
| » Lost to Browns (8-4), 6-3 | Tiger Stadium (3-2) | 6-7 | |
| » Starters: Dick Coffman vs Ownie Carroll | Fourth | 2½ out |
| Monday, April 29 |
| » Lost to Browns (9-4), 3-2 | Tiger Stadium (3-3) | 6-8 | Lost 2 |
| » Starters: Dolly Gray vs Vic Sorrell | Fifth | 3 out |
| Future Tiger Mickey McDermott is born in Poughkeepsie, NY. |
| Tuesday, April 30 |
| » Lost to Browns (10-4), 6-5 | Tiger Stadium (3-4) | 6-9 | Lost 3 |
| » Starters: Jack Ogden vs Emil Yde | Sixth | 4½ out |
| Friday, May 3 |
| » Defeated White Sox (6-7), 6-1 | Comiskey Park I (1-0) | 7-9 | |
| » Starters: George Uhle vs Tommy Thomas | Fifth | 4½ out |
| Saturday, May 4 |
| » Defeated Red Sox (4-8), 2-1 | Tiger Stadium (4-4) | 8-9 | Won 2 |
| » Starters: Red Ruffing vs Vic Sorrell | Fourth | 4 out |
| Sunday, May 5 |
| » Defeated Red Sox (4-9), 10-2 | Tiger Stadium (5-4) | 9-9 | Won 3 |
| » Starters: Ed Morris vs Augie Prudhomme | Fourth | 3 out |
| Monday, May 6 |
| » Defeated Red Sox (4-10), 8-4 | Tiger Stadium (6-4) | 10-9 | Won 4 |
| » Starters: Milt Gaston vs Ownie Carroll | Fourth | 2½ out |
| Tuesday, May 7 |
| » Defeated Senators (4-10), 3-2 | Tiger Stadium (7-4) | 11-9 | Won 5 |
| » Starters: Sam Jones vs Earl Whitehill | Fourth | 3 out |
| Wednesday, May 8 |
| » Defeated Senators (4-11), 5-4 | Tiger Stadium (8-4) | 12-9 | Won 6 |
| » Starters: Bump Hadley vs George Uhle | Fourth | 3 out |
| Thursday, May 9 |
| » Lost to Senators (5-11), 6-3 | Tiger Stadium (8-5) | 12-10 | |
| » Starters: Ad Liska vs Frank Barnes | Fourth | 3 out |
| Friday, May 10 |
| » Lost to Yankees (13-4), 10-5 | Tiger Stadium (8-6) | 12-11 | Lost 2 |
| » Starters: George Pipgras vs Vic Sorrell | Fourth | 4 out |
| Saturday, May 11 |
| » Defeated Yankees (13-5), 13-7 | Tiger Stadium (9-6) | 13-11 | |
| » Starters: Gordon Rhodes vs Ownie Carroll | Fourth | 3 out |
| » Major-league debuts: Lyn Lary and Roy Sherid (Yankees) |
| Sunday, May 12 |
| » Defeated Yankees (13-6), 9-7 | Tiger Stadium (10-6) | 14-11 | Won 2 |
| » Starters: Waite Hoyt vs Earl Whitehill | Third | 3 out |
| Monday, May 13 |
| » Defeated Athletics (13-7), 5-3 | Tiger Stadium (11-6) | 15-11 | Won 3 |
| » Starters: George Earnshaw vs George Uhle | Third | 3 out |
| Tuesday, May 14 |
| » Lost to Athletics (14-7), 10-8 | Tiger Stadium (11-7) | 15-12 | |
| » Starters: Jack Quinn vs Augie Prudhomme | Fourth | 3 out |
| Wednesday, May 15 |
| » Defeated Athletics (14-8), 6-5 | Tiger Stadium (12-7) | 16-12 | |
| » Starters: Rube Walberg vs Vic Sorrell | Fourth | 3 out |
| Thursday, May 16 |
| » Defeated White Sox (10-16), 4-3 | Tiger Stadium (13-7) | 17-12 | Won 2 |
| » Starters: Tommy Thomas vs Ownie Carroll | Fourth | 3½ out |
| Friday, May 17 |
| » Lost to White Sox (11-16), 6-2 | Tiger Stadium (13-8) | 17-13 | |
| » Starters: Red Faber vs Earl Whitehill | Fourth | 3½ out |
| Saturday, May 18 |
| » Defeated White Sox (11-17), 11-4 | Tiger Stadium (14-8) | 18-13 | |
| » Starters: Grady Adkins vs George Uhle | Fourth | 3 out |
| Sunday, May 19 |
| » Lost to White Sox (12-17), 10-3 | Tiger Stadium (14-9) | 18-14 | |
| » Starters: Ted Lyons vs Vic Sorrell | Fourth | 3 out |
| Tuesday, May 21 |
| » Defeated Indians (13-15), 2-1 | Tiger Stadium (15-9) | 19-14 | |
| » Starters: Willis Hudlin vs Ownie Carroll | Fourth | 3 out |
| Wednesday, May 22 |
| » Lost to Indians (14-15), 7-4 | Tiger Stadium (15-10) | 19-15 | |
| » Starters: Jake Miller vs Earl Whitehill | Fourth | 4 out |
| Friday, May 24 |
| » Defeated White Sox (12-21), 6-5 | Comiskey Park I (2-0) | 20-15 | |
| » Starters: George Uhle vs Ted Lyons | Fourth | 5 out |
| Saturday, May 25 |
| » Defeated White Sox (12-22), 5-2 | Comiskey Park I (3-0) | 21-15 | Won 2 |
| » Starters: Vic Sorrell vs Tommy Thomas | Third | 4½ out |
| » Defeated White Sox (12-23), 4-3 | Comiskey Park I (4-0) | 22-15 | Won 3 |
| » Starters: George Smith vs Grady Adkins | Third | 4½ out |
| Sunday, May 26 |
| » Lost to White Sox (13-23), 2-0 | Comiskey Park I (4-1) | 22-16 | |
| » Starters: Ownie Carroll vs Red Faber | Fourth | 5½ out |
| Monday, May 27 |
| » Lost to White Sox (14-23), 7-4 | Comiskey Park I (4-2) | 22-17 | Lost 2 |
| » Starters: Lil Stoner vs Grady Adkins | Fourth | 6½ out |
| » Lost to White Sox (15-23), 6-5 | Comiskey Park I (4-3) | 22-18 | Lost 3 |
| » Starters: Earl Whitehill vs Ed Walsh | Fourth | 6½ out |
| Tuesday, May 28 |
| » Lost to Browns (24-13), 4-2 | Tiger Stadium (15-11) | 22-19 | Lost 4 |
| » Starters: Dolly Gray vs Augie Prudhomme | Fourth | 6½ out |
| Wednesday, May 29 |
| » Defeated Browns (24-14), 7-6 | Tiger Stadium (16-11) | 23-19 | |
| » Starters: Lefty Stewart vs George Uhle | Fourth | 6½ out |
| Thursday, May 30 |
| » Defeated Browns (24-15), 14-6 | Tiger Stadium (17-11) | 24-19 | Won 2 |
| » Starters: Jack Ogden vs Vic Sorrell | Fourth | 7½ out |
| » Lost to Browns (25-15), 13-9 | Tiger Stadium (17-12) | 24-20 | |
| » Starters: Rip Collins vs George Smith | Fourth | 7½ out |
| Friday, May 31 |
| » Lost to Athletics (29-9), 9-6 | Shibe Park (0-1) | 24-21 | Lost 2 |
| » Starters: Ownie Carroll vs Howard Ehmke | Fourth | 8½ out |
| Saturday, June 1 |
| » Lost to Athletics (30-9), 11-2 | Shibe Park (0-2) | 24-22 | Lost 3 |
| » Starters: Earl Whitehill vs George Earnshaw | Fourth | 9½ out |
| Monday, June 3 |
| » Lost to Athletics (31-9), 3-2 | Shibe Park (0-3) | 24-23 | Lost 4 |
| » Starters: George Uhle vs Lefty Grove | Fourth | 10½ out |
| Tuesday, June 4 |
| » Defeated Athletics (31-10), 8-4 | Shibe Park (1-3) | 25-23 | |
| » Starters: Vic Sorrell vs Jack Quinn | Fourth | 9½ out |
| Wednesday, June 5 |
| » Lost to Senators (16-25), 8-2 | Griffith Stadium (0-1) | 25-24 | |
| » Starters: Ownie Carroll vs Firpo Marberry | Fourth | 10½ out |
| Thursday, June 6 |
| » Defeated Senators (16-26), 7-5 | Griffith Stadium (1-1) | 26-24 | |
| » Starters: Earl Whitehill vs Bump Hadley | Fourth | 10½ out |
| Friday, June 7 |
| » Defeated Senators (16-27), 17-11 | Griffith Stadium (2-1) | 27-24 | Won 2 |
| » Starters: Augie Prudhomme vs Garland Braxton | Fourth | 9½ out |
| Sunday, June 9 |
| » Lost to Red Sox (15-31), 7-6 | Braves Field (0-1) | 27-25 | |
| » Starters: George Uhle vs Ed Morris | Fourth | 10 out |
| Monday, June 10 |
| » Defeated Red Sox (15-32), 1-0 | Fenway Park (1-0) | 28-25 | |
| » Starters: Vic Sorrell vs Red Ruffing | Fourth | 10 out |
| Tuesday, June 11 |
| » Defeated Red Sox (15-33), 5-3 | Fenway Park (2-0) | 29-25 | Won 2 |
| » Starters: Ownie Carroll vs Danny MacFayden | Fourth | 10 out |
| Thursday, June 13 |
| » Lost to Yankees (29-19), 8-5 | Yankee Stadium (0-1) | 29-26 | |
| » Starters: Earl Whitehill vs Ed Wells | Fourth | 11½ out |
| Friday, June 14 |
| » Lost to Yankees (30-19), 15-4 | Yankee Stadium (0-2) | 29-27 | Lost 2 |
| » Starters: George Uhle vs Waite Hoyt | Fourth | 12½ out |
| Saturday, June 15 |
| » Defeated Yankees (30-20), 9-2 | Yankee Stadium (1-2) | 30-27 | |
| » Starters: Vic Sorrell vs George Pipgras | Fourth | 12½ out |
| Sunday, June 16 |
| » Lost to Yankees (31-20), 11-7 | Yankee Stadium (1-3) | 30-28 | |
| » Starters: Lil Stoner vs Herb Pennock | Fourth | 12½ out |
| Monday, June 17 |
| » Lost to Red Sox (17-36), 6-5 | Fenway Park (2-1) | 30-29 | Lost 2 |
| » Starters: Ownie Carroll vs Red Ruffing | Fourth | 12 out |
| » Defeated Red Sox (17-37), 8-3 | Fenway Park (3-1) | 31-29 | |
| » Starters: George Uhle vs Milt Gaston | Fourth | 12 out |
| Wednesday, June 19 |
| » Defeated Indians (26-28), 8-3 | League Park II (2-3) | 32-29 | Won 2 |
| » Starters: Emil Yde vs Willis Hudlin | Fourth | 12 out |
| Thursday, June 20 |
| » Defeated Indians (26-29), 8-4 | League Park II (3-3) | 33-29 | Won 3 |
| » Starters: Vic Sorrell vs Jimmy Zinn | Fourth | 11½ out |
| Saturday, June 22 |
| » Lost to Indians (27-29), 4-3 | League Park II (3-4) | 33-30 | |
| » Starters: Ownie Carroll vs Wes Ferrell | Fourth | 12 out |
| Sunday, June 23 |
| » Defeated Indians (27-30), 8-7 | League Park II (4-4) | 34-30 | |
| » Starters: George Uhle vs Willis Hudlin | Third | 12 out |
| Monday, June 24 |
| » Defeated White Sox (22-41), 13-4 | Tiger Stadium (18-12) | 35-30 | Won 2 |
| » Starters: Red Faber vs Emil Yde | Fourth | 12 out |
| Tuesday, June 25 |
| » Defeated White Sox (22-42), 14-2 | Tiger Stadium (19-12) | 36-30 | Won 3 |
| » Starters: Ed Walsh vs Vic Sorrell | Fourth | 12½ out |
| Wednesday, June 26 |
| » Lost to White Sox (23-42), 5-3 | Tiger Stadium (19-13) | 36-31 | |
| » Starters: Ted Lyons vs Augie Prudhomme | Fourth | 13½ out |
| Thursday, June 27 |
| » Defeated Indians (29-33), 6-2 | Tiger Stadium (20-13) | 37-31 | |
| » Starters: Wes Ferrell vs Ownie Carroll | Fourth | 13½ out |
| Future Tiger Dick Marlowe is born in Hickory, NC. |
| Friday, June 28 |
| » Lost to Indians (30-33), 5-4 | Tiger Stadium (20-14) | 37-32 | |
| » Starters: Johnny Miljus vs George Uhle | Fourth | 14 out |
| Saturday, June 29 |
| » Lost to Indians (31-33), 12-9 | Tiger Stadium (20-15) | 37-33 | Lost 2 |
| » Starters: Jake Miller vs Emil Yde | Fourth | 14 out |
| Sunday, June 30 |
| » Defeated Indians (31-34), 11-10 | Tiger Stadium (21-15) | 38-33 | |
| » Starters: Jimmy Zinn vs Vic Sorrell | Fourth | 13 out |
| Tuesday, July 2 |
| » Defeated Browns (41-27), 10-4 | Sportsman's Park III (3-2) | 39-33 | Won 2 |
| » Starters: Earl Whitehill vs Dolly Gray | Fourth | 13½ out |
| Wednesday, July 3 |
| » Lost to Browns (42-27), 8-6 | Sportsman's Park III (3-3) | 39-34 | |
| » Starters: George Uhle vs Alvin Crowder | Fourth | 14½ out |
| Thursday, July 4 |
| » Lost to Browns (43-27), 12-6 | Sportsman's Park III (3-4) | 39-35 | Lost 2 |
| » Starters: Vic Sorrell vs Rip Collins | Fourth | 16½ out |
| » Lost to Browns (44-27), 7-6 | Sportsman's Park III (3-5) | 39-36 | Lost 3 |
| » Starters: Ownie Carroll vs George Blaeholder | Fourth | 16½ out |
| Future Tiger Babe Birrer is born in Buffalo, NY. Future Tiger Bill Tuttle is born in Elwood, IL. |
| Sunday, July 7 |
| » Defeated Senators (26-43), 9-1 | Tiger Stadium (22-15) | 40-36 | |
| » Starters: Firpo Marberry vs Earl Whitehill | Fourth | 15 out |
| Monday, July 8 |
| » Lost to Senators (27-43), 5-4 | Tiger Stadium (22-16) | 40-37 | |
| » Starters: Sam Jones vs George Uhle | Fourth | 15½ out |
| » Defeated Senators (27-44), 16-6 | Tiger Stadium (23-16) | 41-37 | |
| » Starters: Lloyd Brown vs Emil Yde | Fourth | 15½ out |
| Tuesday, July 9 |
| » Lost to Senators (28-44), 2-1 | Tiger Stadium (23-17) | 41-38 | |
| » Starters: Garland Braxton vs Ownie Carroll | Fourth | 15½ out |
| Wednesday, July 10 |
| » Defeated Red Sox (23-56), 10-6 | Tiger Stadium (24-17) | 42-38 | |
| » Starters: Milt Gaston vs Vic Sorrell | Fourth | 15 out |
| Thursday, July 11 |
| » Lost to Red Sox (24-56), 15-8 | Tiger Stadium (24-18) | 42-39 | |
| » Starters: Jack Russell vs Augie Prudhomme | Fourth | 15½ out |
| Friday, July 12 |
| » Defeated Red Sox (24-57), 13-12 | Tiger Stadium (25-18) | 43-39 | |
| » Starters: Red Ruffing vs Earl Whitehill | Fourth | 16 out |
| Former Tiger John Cronin dies in Middletown, NY at the age of 56. |
| Sunday, July 14 |
| » Defeated Yankees (49-29), 7-3 | Tiger Stadium (26-18) | 44-39 | Won 2 |
| » Starters: George Pipgras vs George Uhle | Fourth | 16 out |
| Monday, July 15 |
| » Lost to Yankees (50-29), 7-6 | Tiger Stadium (26-19) | 44-40 | |
| » Starters: Roy Sherid vs Ownie Carroll | Fourth | 16½ out |
| Tuesday, July 16 |
| » Lost to Yankees (51-29), 11-7 | Tiger Stadium (26-20) | 44-41 | Lost 2 |
| » Starters: Ed Wells vs Vic Sorrell | Fourth | 17½ out |
| Wednesday, July 17 |
| » Defeated Yankees (51-30), 9-8 | Tiger Stadium (27-20) | 45-41 | |
| » Starters: Waite Hoyt vs Earl Whitehill | Fourth | 16½ out |
| Thursday, July 18 |
| » Lost to Athletics (62-24), 8-4 | Tiger Stadium (27-21) | 45-42 | |
| » Starters: Rube Walberg vs George Uhle | Fourth | 17½ out |
| Friday, July 19 |
| » Lost to Athletics (63-24), 4-2 | Tiger Stadium (27-22) | 45-43 | Lost 2 |
| » Starters: George Earnshaw vs Ownie Carroll | Fourth | 18½ out |
| Saturday, July 20 |
| » Lost to Athletics (64-24), 6-2 | Tiger Stadium (27-23) | 45-44 | Lost 3 |
| » Starters: Lefty Grove vs Vic Sorrell | Fourth | 19½ out |
| Sunday, July 21 |
| » Lost to Athletics (65-24), 10-7 | Tiger Stadium (27-24) | 45-45 | Lost 4 |
| » Starters: Bill Shores vs Skinny Graham | Fifth | 20½ out |
| Tuesday, July 23 |
| » Lost to Yankees (54-33), 7-5 | Yankee Stadium (1-4) | 45-46 | Lost 5 |
| » Starters: Earl Whitehill vs George Pipgras | Fifth | 21 out |
| Wednesday, July 24 |
| » Lost to Yankees (55-33), 7-5 | Yankee Stadium (1-5) | 45-47 | Lost 6 |
| » Starters: George Uhle vs Herb Pennock | Fifth | 22 out |
| Friday, July 26 |
| » Defeated Red Sox (27-65), 4-1 | Fenway Park (4-1) | 46-47 | |
| » Starters: Ownie Carroll vs Milt Gaston | Fifth | 22½ out |
| Saturday, July 27 |
| » Lost to Red Sox (28-65), 4-0 | Fenway Park (4-2) | 46-48 | |
| » Starters: Vic Sorrell vs Red Ruffing | Fifth | 23½ out |
| Sunday, July 28 |
| » Defeated Red Sox (28-66), 5-3 | Braves Field (1-1) | 47-48 | |
| » Starters: Skinny Graham vs Jack Russell | Fifth | 23 out |
| Tuesday, July 30 |
| » Lost to Athletics (71-26), 5-4 | Shibe Park (1-4) | 47-49 | |
| » Starters: George Uhle vs Lefty Grove | Fifth | 23½ out |
| Wednesday, July 31 |
| » Lost to Athletics (72-26), 10-1 | Shibe Park (1-5) | 47-50 | Lost 2 |
| » Starters: Ownie Carroll vs Rube Walberg | Fifth | 24½ out |
| Thursday, August 1 |
| » Lost to Athletics (73-26), 7-4 | Shibe Park (1-6) | 47-51 | Lost 3 |
| » Starters: Vic Sorrell vs George Earnshaw | Fifth | 25½ out |
| Friday, August 2 |
| » Lost to Athletics (74-26), 11-10 | Shibe Park (1-7) | 47-52 | Lost 4 |
| » Starters: Skinny Graham vs Jack Quinn | Fifth | 26½ out |
| Sunday, August 4 |
| » Defeated Senators (38-58), 10-5 | Griffith Stadium (3-1) | 48-52 | |
| » Starters: Earl Whitehill vs Garland Braxton | Fifth | 25½ out |
| » Defeated Senators (38-59), 13-11 | Griffith Stadium (4-1) | 49-52 | Won 2 |
| » Starters: George Uhle vs Bobby Burke | Fifth | 25½ out |
| Monday, August 5 |
| » Lost to Senators (39-59), 21-5 | Griffith Stadium (4-2) | 49-53 | |
| » Starters: George Uhle vs Lloyd Brown | Fifth | 26 out |
| Tuesday, August 6 |
| » Lost to Indians (55-48), 6-5 | League Park II (4-5) | 49-54 | Lost 2 |
| » Starters: Vic Sorrell vs Willis Hudlin | Fourth | 26½ out |
| Wednesday, August 7 |
| » Defeated Indians (55-49), 14-4 | League Park II (5-5) | 50-54 | |
| » Starters: Ownie Carroll vs Joe Shaute | Fifth | 26 out |
| Thursday, August 8 |
| » Defeated Indians (55-50), 9-6 | League Park II (6-5) | 51-54 | Won 2 |
| » Starters: Skinny Graham vs Johnny Miljus | Fourth | 25 out |
| Saturday, August 10 |
| » Lost to Athletics (78-30), 6-5 | Tiger Stadium (27-25) | 51-55 | |
| » Starters: Lefty Grove vs Earl Whitehill | Fifth | 26 out |
| Sunday, August 11 |
| » Defeated Athletics (78-31), 9-8 | Tiger Stadium (28-25) | 52-55 | |
| » Starters: George Earnshaw vs Vic Sorrell | Fifth | 25 out |
| Monday, August 12 |
| » Lost to Athletics (79-31), 6-0 | Tiger Stadium (28-26) | 52-56 | |
| » Starters: Rube Walberg vs George Uhle | Fifth | 26 out |
| Tuesday, August 13 |
| » Lost to Athletics (80-31), 4-3 | Tiger Stadium (28-27) | 52-57 | Lost 2 |
| » Starters: Jack Quinn vs Vic Sorrell | Fifth | 27 out |
| Wednesday, August 14 |
| » Defeated Yankees (65-42), 17-13 | Tiger Stadium (29-27) | 53-57 | |
| » Starters: George Pipgras vs Skinny Graham | Fifth | 27 out |
| Thursday, August 15 |
| » Defeated Yankees (65-43), 3-0 | Tiger Stadium (30-27) | 54-57 | Won 2 |
| » Starters: Roy Sherid vs Earl Whitehill | Fifth | 26½ out |
| Friday, August 16 |
| » Lost to Yankees (66-43), 12-2 | Tiger Stadium (30-28) | 54-58 | |
| » Starters: Ed Wells vs George Uhle | Fifth | 27½ out |
| Saturday, August 17 |
| » Lost to Yankees (67-43), 7-2 | Tiger Stadium (30-29) | 54-59 | Lost 2 |
| » Starters: Waite Hoyt vs Vic Sorrell | Fifth | 27½ out |
| Sunday, August 18 |
| » Lost to Red Sox (38-74), 5-4 | Tiger Stadium (30-30) | 54-60 | Lost 3 |
| » Starters: Ed Morris vs Ownie Carroll | Fifth | 27½ out |
| Monday, August 19 |
| » Lost to Red Sox (39-74), 3-2 | Tiger Stadium (30-31) | 54-61 | Lost 4 |
| » Starters: Milt Gaston vs Earl Whitehill | Fifth | 28 out |
| » Defeated Red Sox (39-75), 6-2 | Tiger Stadium (31-31) | 55-61 | |
| » Starters: Jack Russell vs Vic Sorrell | Fifth | 28 out |
| Tuesday, August 20 |
| » Lost to Red Sox (40-75), 12-8 | Tiger Stadium (31-32) | 55-62 | |
| » Starters: Red Ruffing vs Skinny Graham | Fifth | 28 out |
| Wednesday, August 21 |
| » Defeated Red Sox (40-76), 13-2 | Tiger Stadium (32-32) | 56-62 | |
| » Starters: Bill Bayne vs George Uhle | Fifth | 27 out |
| Thursday, August 22 |
| » Lost to Senators (51-64), 6-1 | Tiger Stadium (32-33) | 56-63 | |
| » Starters: Garland Braxton vs Ownie Carroll | Fifth | 27 out |
| Friday, August 23 |
| » Lost to Senators (52-64), 1-0 | Tiger Stadium (32-34) | 56-64 | Lost 2 |
| » Starters: Sam Jones vs Earl Whitehill | Fifth | 27 out |
| Saturday, August 24 |
| » Lost to Senators (53-64), 9-6 | Tiger Stadium (32-35) | 56-65 | Lost 3 |
| » Starters: Myles Thomas vs Vic Sorrell | Fifth | 28 out |
| Sunday, August 25 |
| » Defeated Senators (53-65), 8-7 | Tiger Stadium (33-35) | 57-65 | |
| » Starters: Bump Hadley vs Phil Page | Fifth | 27 out |
| Thursday, August 29 |
| » Lost to Browns (66-57), 6-0 | Sportsman's Park III (3-6) | 57-66 | |
| » Starters: Earl Whitehill vs Dolly Gray | Fifth | 28 out |
| Saturday, August 31 |
| » Defeated Browns (66-58), 13-9 | Sportsman's Park III (4-6) | 58-66 | |
| » Starters: Phil Page vs Alvin Crowder | Fifth | 27½ out |
| Sunday, September 1 |
| » Defeated Browns (66-59), 7-4 | Sportsman's Park III (5-6) | 59-66 | Won 2 |
| » Starters: George Uhle vs George Blaeholder | Fifth | 26½ out |
| Monday, September 2 |
| » Defeated White Sox (50-76), 10-8 | Tiger Stadium (34-35) | 60-66 | Won 3 |
| » Starters: Red Faber vs Ownie Carroll | Fifth | 27½ out |
| » Lost to White Sox (51-76), 8-2 | Tiger Stadium (34-36) | 60-67 | |
| » Starters: Ted Lyons vs Vic Sorrell | Fifth | 27½ out |
| Wednesday, September 4 |
| » Lost to Indians (68-59), 7-2 | Tiger Stadium (34-37) | 60-68 | Lost 2 |
| » Starters: Wes Ferrell vs Earl Whitehill | Fifth | 28½ out |
| Thursday, September 5 |
| » Lost to Indians (69-59), 4-0 | Tiger Stadium (34-38) | 60-69 | Lost 3 |
| » Starters: Ken Holloway vs Phil Page | Fifth | 29 out |
| Saturday, September 7 |
| » Defeated Yankees (74-55), 5-4 | Yankee Stadium (2-5) | 61-69 | |
| » Starters: George Uhle vs Ed Wells | Fifth | 29 out |
| » Lost to Yankees (75-55), 11-7 | Yankee Stadium (2-6) | 61-70 | |
| » Starters: Ownie Carroll vs Waite Hoyt | Fifth | 29 out |
| Sunday, September 8 |
| » Lost to Yankees (76-55), 9-3 | Yankee Stadium (2-7) | 61-71 | Lost 2 |
| » Starters: Vic Sorrell vs Roy Sherid | Fifth | 29½ out |
| Tuesday, September 10 |
| » Defeated Yankees (76-56), 8-4 | Yankee Stadium (3-7) | 62-71 | |
| » Starters: Earl Whitehill vs Herb Pennock | Fifth | 30 out |
| » Lost to Yankees (77-56), 10-9 | Yankee Stadium (3-8) | 62-72 | |
| » Starters: Phil Page vs George Pipgras | Fifth | 30 out |
| Wednesday, September 11 |
| » Lost to Red Sox (50-87), 8-7 | Fenway Park (4-3) | 62-73 | Lost 2 |
| » Starters: Vic Sorrell vs Red Ruffing | Sixth | 31 out |
| Thursday, September 12 |
| » Defeated Red Sox (50-88), 2-1 | Fenway Park (5-3) | 63-73 | |
| » Starters: Art Herring vs Ed Morris | Fifth | 31 out |
| Saturday, September 14 |
| » Defeated Red Sox (50-89), 2-1 | Fenway Park (6-3) | 64-73 | Won 2 |
| » Starters: Ownie Carroll vs Milt Gaston | Fifth | 31½ out |
| Sunday, September 15 |
| » Defeated Senators (62-75), 16-2 | Griffith Stadium (5-2) | 65-73 | Won 3 |
| » Starters: Earl Whitehill vs Myles Thomas | Fifth | 31 out |
| » Tied Senators, 3-3 | Griffith Stadium (5-2) | 65-73 | |
| » Starters: George Uhle vs Firpo Marberry | Fifth | 31 out |
| Monday, September 16 |
| » Lost to Senators (63-75), 10-9 | Griffith Stadium (5-3) | 65-74 | |
| » Starters: Whit Wyatt vs Bump Hadley | Fifth | 31 out |
| » Major-league debuts: Whit Wyatt (Tigers) |
| Tuesday, September 17 |
| » Lost to Senators (64-75), 4-1 | Griffith Stadium (5-4) | 65-75 | Lost 2 |
| » Starters: Vic Sorrell vs Sam Jones | Fifth | 31½ out |
| Wednesday, September 18 |
| » Lost to Senators (65-75), 2-0 | Griffith Stadium (5-5) | 65-76 | Lost 3 |
| » Starters: Earl Whitehill vs Bump Hadley | Sixth | 32½ out |
| » Lost to Senators (66-75), 1-0 | Griffith Stadium (5-6) | 65-77 | Lost 4 |
| » Starters: Chief Hogsett vs Lloyd Brown | Sixth | 32½ out |
| » Major-league debuts: Chief Hogsett (Tigers) |
| Thursday, September 19 |
| » Lost to Athletics (98-44), 5-4 | Shibe Park (1-8) | 65-78 | Lost 5 |
| » Starters: Art Herring vs Rube Walberg | Sixth | 33½ out |
| Friday, September 20 |
| » Lost to Athletics (99-44), 2-1 | Shibe Park (1-9) | 65-79 | Lost 6 |
| » Starters: Whit Wyatt vs Bill Shores | Sixth | 34½ out |
| Saturday, September 21 |
| » Lost to Athletics (100-44), 10-7 | Shibe Park (1-10) | 65-80 | Lost 7 |
| » Starters: George Uhle vs Bill Breckinridge | Fifth | 35½ out |
| Sunday, September 22 |
| » Defeated Browns (75-69), 5-0 | Tiger Stadium (35-38) | 66-80 | |
| » Starters: Dolly Gray vs Chief Hogsett | Sixth | 34½ out |
| Tuesday, September 24 |
| » Defeated Browns (75-70), 9-4 | Tiger Stadium (36-38) | 67-80 | Won 2 |
| » Starters: Alvin Crowder vs Art Herring | Sixth | 34 out |
| Wednesday, September 25 |
| » Lost to Browns (76-70), 3-2 | Tiger Stadium (36-39) | 67-81 | |
| » Starters: George Blaeholder vs Earl Whitehill | Sixth | 34½ out |
| Saturday, September 28 |
| » Defeated White Sox (56-91), 11-10 | Tiger Stadium (37-39) | 68-81 | |
| » Starters: Tommy Thomas vs Chief Hogsett | Sixth | 35 out |
| Sunday, September 29 |
| » Defeated White Sox (56-92), 9-8 | Tiger Stadium (38-39) | 69-81 | Won 2 |
| » Starters: Red Faber vs Whit Wyatt | Sixth | 34 out |
| Thursday, October 3 |
| » Lost to White Sox (57-92), 3-1 | Comiskey Park I (4-4) | 69-82 | |
| » Starters: Chief Hogsett vs Ted Lyons | Sixth | 34½ out |
| Friday, October 4 |
| » Lost to White Sox (58-92), 14-6 | Comiskey Park I (4-5) | 69-83 | Lost 2 |
| » Starters: Art Herring vs Dutch Henry | Sixth | 35 out |
| Saturday, October 5 |
| » Defeated White Sox (58-93), 6-3 | Comiskey Park I (5-5) | 70-83 | |
| » Starters: Earl Whitehill vs Jerry Byrne | Sixth | 35 out |
| Sunday, October 6 |
| » Lost to White Sox (59-93), 8-7 | Comiskey Park I (5-6) | 70-84 | |
| » Starters: Whit Wyatt vs Ed Walsh | Sixth | 36 out |
| Wednesday, November 20 |
| Future Tiger Lou Berberet is born in Long Beach, CA. |
| Sunday, December 15 |
| Future Tiger Ray Herbert is born in Detroit, MI. |
| Monday, December 23 |
| Future Tiger Al Cicotte is born in Melvindale, MI. |
Game information provided by Retrosheet (www.retrosheet.org) |