| Thursday, January 3 |
| Former Senator Charlie Smith dies in Wickliffe, OH at the age of 49. |
| Monday, February 18 |
| Future Senator Cal Neeman is born in Valmeyer, IL. |
| Friday, February 22 |
| Future Senator Ryne Duren is born in Cazenovia, WI. |
| Wednesday, April 17 |
| » Lost to Athletics (1-0), 13-4 | Griffith Stadium (0-1) | 0-1 | |
| » Starters: Carroll Yerkes vs Sam Jones | Fifth | 1½ out |
| » Major-league debuts: Ad Liska (Senators) |
| Thursday, April 18 |
| » Lost to Athletics (2-0), 8-2 | Griffith Stadium (0-2) | 0-2 | Lost 2 |
| » Starters: Rube Walberg vs Bump Hadley | Seventh | 2½ out |
| Friday, April 19 |
| » Defeated Red Sox (0-2), 3-1 | Griffith Stadium (1-2) | 1-2 | |
| » Starters: Ed Morris vs Firpo Marberry | Fourth | 1½ out |
| » Major-league debuts: Ed Durham (Red Sox) |
| Saturday, April 20 |
| » Lost to Red Sox (1-2), 6-5 | Griffith Stadium (1-3) | 1-3 | |
| » Starters: Jack Russell vs Sam Jones | Sixth | 2 out |
| Sunday, April 21 |
| » Major-league debuts: Chad Kimsey (Browns) |
| Tuesday, April 23 |
| » Defeated Athletics (3-2), 4-3 | Shibe Park (1-0) | 2-3 | |
| » Starters: Bump Hadley vs Rube Walberg | Fifth | 1½ out |
| Wednesday, April 24 |
| » Lost to Athletics (4-2), 9-4 | Shibe Park (1-1) | 2-4 | |
| » Starters: Firpo Marberry vs George Earnshaw | Seventh | 2 out |
| Friday, April 26 |
| » Lost to Red Sox (3-3), 2-1 | Fenway Park (0-1) | 2-5 | Lost 2 |
| » Starters: Ad Liska vs Jack Russell | Sixth | 3 out |
| Saturday, April 27 |
| » Defeated Red Sox (3-4), 3-2 | Fenway Park (1-1) | 3-5 | |
| » Starters: Sam Jones vs Danny MacFayden | Seventh | 2½ out |
| Sunday, April 28 |
| » Lost to Yankees (5-3), 7-2 | Griffith Stadium (1-4) | 3-6 | |
| » Starters: Waite Hoyt vs Bump Hadley | Eighth | 3½ out |
| Monday, April 29 |
| Future Senator Mickey McDermott is born in Poughkeepsie, NY. Future Senator Steve Ridzik is born in Yonkers, NY. |
| Tuesday, April 30 |
| » Lost to Yankees (6-4), 10-9 | Yankee Stadium (0-1) | 3-7 | Lost 2 |
| » Starters: Garland Braxton vs Tom Zachary | Eighth | 5 out |
| Saturday, May 4 |
| » Lost to Indians (6-9), 4-3 | League Park II (0-1) | 3-8 | Lost 3 |
| » Starters: Bump Hadley vs Joe Shaute | Eighth | 6 out |
| Sunday, May 5 |
| » Lost to Indians (7-9), 1-0 | League Park II (0-2) | 3-9 | Lost 4 |
| » Starters: Ad Liska vs Jake Miller | Eighth | 6 out |
| Monday, May 6 |
| » Defeated Indians (7-10), 13-5 | League Park II (1-2) | 4-9 | |
| » Starters: Garland Braxton vs Ken Holloway | Seventh | 5½ out |
| Tuesday, May 7 |
| » Lost to Tigers (11-9), 3-2 | Tiger Stadium (0-1) | 4-10 | |
| » Starters: Sam Jones vs Earl Whitehill | Eighth | 6 out |
| Wednesday, May 8 |
| » Lost to Tigers (12-9), 5-4 | Tiger Stadium (0-2) | 4-11 | Lost 2 |
| » Starters: Bump Hadley vs George Uhle | Eighth | 7 out |
| Thursday, May 9 |
| » Defeated Tigers (12-10), 6-3 | Tiger Stadium (1-2) | 5-11 | |
| » Starters: Ad Liska vs Frank Barnes | Seventh | 7 out |
| Friday, May 10 |
| » Defeated White Sox (7-13), 4-2 | Comiskey Park I (1-0) | 6-11 | Won 2 |
| » Starters: Garland Braxton vs Bob Weiland | Sixth | 7 out |
| Saturday, May 11 |
| » Defeated White Sox (7-14), 9-2 | Comiskey Park I (2-0) | 7-11 | Won 3 |
| » Starters: Sam Jones vs Tommy Thomas | Sixth | 6 out |
| Sunday, May 12 |
| » Lost to White Sox (8-14), 3-2 | Comiskey Park I (2-1) | 7-12 | |
| » Starters: Bobby Burke vs Red Faber | Fifth | 6 out |
| Tuesday, May 14 |
| » Defeated Browns (13-10), 9-7 | Sportsman's Park III (1-0) | 8-12 | |
| » Starters: Ad Liska vs Dolly Gray | Sixth | 5½ out |
| Wednesday, May 15 |
| » Lost to Browns (14-10), 5-3 | Sportsman's Park III (1-1) | 8-13 | |
| » Starters: Garland Braxton vs Lefty Stewart | Seventh | 5½ out |
| Friday, May 17 |
| » Lost to Athletics (15-8), 4-1 | Griffith Stadium (1-5) | 8-14 | Lost 2 |
| » Starters: Lefty Grove vs Bump Hadley | Seventh | 6½ out |
| Saturday, May 18 |
| » Lost to Athletics (16-8), 5-4 | Griffith Stadium (1-6) | 8-15 | Lost 3 |
| » Starters: George Earnshaw vs Sam Jones | Seventh | 8½ out |
| » Lost to Athletics (17-8), 7-5 | Griffith Stadium (1-7) | 8-16 | Lost 4 |
| » Starters: Jack Quinn vs Lloyd Brown | Seventh | 8½ out |
| Sunday, May 19 |
| » Lost to Athletics (18-8), 7-0 | Griffith Stadium (1-8) | 8-17 | Lost 5 |
| » Starters: Rube Walberg vs Bobby Burke | Seventh | 9½ out |
| Wednesday, May 22 |
| » Defeated Yankees (16-10), 10-2 | Yankee Stadium (1-1) | 9-17 | |
| » Starters: Sam Jones vs Hank Johnson | Seventh | 9½ out |
| » Defeated Yankees (16-11), 3-2 | Yankee Stadium (2-1) | 10-17 | Won 2 |
| » Starters: Garland Braxton vs Waite Hoyt | Seventh | 9½ out |
| Thursday, May 23 |
| » Lost to Athletics (21-8), 9-8 | Shibe Park (1-2) | 10-18 | |
| » Starters: Bump Hadley vs George Earnshaw | Seventh | 11½ out |
| » Lost to Athletics (22-8), 9-8 | Shibe Park (1-3) | 10-19 | Lost 2 |
| » Starters: Lloyd Brown vs Rube Walberg | Seventh | 11½ out |
| Friday, May 24 |
| » Lost to Athletics (23-8), 10-3 | Shibe Park (1-4) | 10-20 | Lost 3 |
| » Starters: Bump Hadley vs George Earnshaw | Seventh | 12½ out |
| Saturday, May 25 |
| » Lost to Athletics (24-8), 5-4 | Shibe Park (1-5) | 10-21 | Lost 4 |
| » Starters: Firpo Marberry vs Lefty Grove | Seventh | 13½ out |
| Sunday, May 26 |
| » Lost to Athletics (25-8), 4-3 | Griffith Stadium (1-9) | 10-22 | Lost 5 |
| » Starters: Jack Quinn vs Garland Braxton | Seventh | 14½ out |
| Tuesday, May 28 |
| » Lost to Yankees (20-13), 12-7 | Griffith Stadium (1-10) | 10-23 | Lost 6 |
| » Starters: Ed Wells vs Bump Hadley | Eighth | 14½ out |
| Wednesday, May 29 |
| » Defeated Yankees (20-14), 8-3 | Griffith Stadium (2-10) | 11-23 | |
| » Starters: George Pipgras vs Firpo Marberry | Seventh | 14½ out |
| Thursday, May 30 |
| » Defeated Yankees (20-15), 8-5 | Griffith Stadium (3-10) | 12-23 | Won 2 |
| » Starters: Herb Pennock vs Garland Braxton | Seventh | 14½ out |
| » Defeated Yankees (20-16), 4-3 | Griffith Stadium (4-10) | 13-23 | Won 3 |
| » Starters: Hank Johnson vs Bump Hadley | Seventh | 14½ out |
| Saturday, June 1 |
| » Lost to Browns (26-15), 5-4 | Griffith Stadium (4-11) | 13-24 | |
| » Starters: Lefty Stewart vs Bobby Burke | Seventh | 16 out |
| Sunday, June 2 |
| » Defeated Browns (26-16), 2-1 | Griffith Stadium (5-11) | 14-24 | |
| » Starters: George Blaeholder vs Bump Hadley | Sixth | 15½ out |
| Monday, June 3 |
| » Lost to Browns (27-16), 6-4 | Griffith Stadium (5-12) | 14-25 | |
| » Starters: Dolly Gray vs Garland Braxton | Sixth | 16½ out |
| Tuesday, June 4 |
| » Defeated Browns (27-17), 8-7 | Griffith Stadium (6-12) | 15-25 | |
| » Starters: Rip Collins vs Ad Liska | Sixth | 15½ out |
| Wednesday, June 5 |
| » Defeated Tigers (25-24), 8-2 | Griffith Stadium (7-12) | 16-25 | Won 2 |
| » Starters: Ownie Carroll vs Firpo Marberry | Sixth | 15½ out |
| Thursday, June 6 |
| » Lost to Tigers (26-24), 7-5 | Griffith Stadium (7-13) | 16-26 | |
| » Starters: Earl Whitehill vs Bump Hadley | Sixth | 16½ out |
| Friday, June 7 |
| » Lost to Tigers (27-24), 17-11 | Griffith Stadium (7-14) | 16-27 | Lost 2 |
| » Starters: Augie Prudhomme vs Garland Braxton | Sixth | 16½ out |
| Sunday, June 9 |
| » Defeated Indians (23-23), 5-2 | Griffith Stadium (8-14) | 17-27 | |
| » Starters: Johnny Miljus vs Ad Liska | Sixth | 16 out |
| Monday, June 10 |
| » Lost to Indians (24-23), 4-3 | Griffith Stadium (8-15) | 17-28 | |
| » Starters: Joe Shaute vs Bump Hadley | Sixth | 17 out |
| Tuesday, June 11 |
| » Defeated Indians (24-24), 13-3 | Griffith Stadium (9-15) | 18-28 | |
| » Starters: Jake Miller vs Firpo Marberry | Sixth | 17 out |
| Wednesday, June 12 |
| » Lost to Indians (25-24), 9-5 | Griffith Stadium (9-16) | 18-29 | |
| » Starters: Willis Hudlin vs Bobby Burke | Sixth | 18 out |
| Thursday, June 13 |
| » Lost to White Sox (19-35), 11-8 | Griffith Stadium (9-17) | 18-30 | Lost 2 |
| » Starters: Red Faber vs Garland Braxton | Sixth | 19 out |
| Friday, June 14 |
| » Defeated White Sox (19-36), 4-1 | Griffith Stadium (10-17) | 19-30 | |
| » Starters: Grady Adkins vs Bump Hadley | Sixth | 19 out |
| Saturday, June 15 |
| » Lost to White Sox (20-36), 5-1 | Griffith Stadium (10-18) | 19-31 | |
| » Starters: Ed Walsh vs Ad Liska | Sixth | 20 out |
| Sunday, June 16 |
| » Defeated White Sox (20-37), 5-3 | Griffith Stadium (11-18) | 20-31 | |
| » Starters: Ted Lyons vs Firpo Marberry | Sixth | 19 out |
| Tuesday, June 18 |
| » Lost to Athletics (40-13), 7-6 | Griffith Stadium (11-19) | 20-32 | |
| » Starters: Lefty Grove vs Bump Hadley | Sixth | 19½ out |
| Thursday, June 20 |
| » Lost to Red Sox (19-39), 6-4 | Griffith Stadium (11-20) | 20-33 | Lost 2 |
| » Starters: Danny MacFayden vs Ad Liska | Sixth | 20 out |
| Friday, June 21 |
| » Defeated Red Sox (19-40), 5-4 | Griffith Stadium (12-20) | 21-33 | |
| » Starters: Red Ruffing vs Firpo Marberry | Sixth | 19½ out |
| Saturday, June 22 |
| » Defeated Red Sox (19-41), 3-2 | Griffith Stadium (13-20) | 22-33 | Won 2 |
| » Starters: Milt Gaston vs Lloyd Brown | Sixth | 18½ out |
| » Defeated Red Sox (19-42), 5-1 | Griffith Stadium (14-20) | 23-33 | Won 3 |
| » Starters: Ed Morris vs Bobby Burke | Sixth | 18½ out |
| Sunday, June 23 |
| » Defeated Red Sox (19-43), 7-1 | Griffith Stadium (15-20) | 24-33 | Won 4 |
| » Starters: Bill Bayne vs Myles Thomas | Fifth | 18½ out |
| Wednesday, June 26 |
| » Lost to Yankees (36-24), 7-0 | Griffith Stadium (15-21) | 24-34 | |
| » Starters: Herb Pennock vs Firpo Marberry | Sixth | 20½ out |
| » Defeated Yankees (36-25), 4-3 | Griffith Stadium (16-21) | 25-34 | |
| » Starters: Fred Heimach vs Lloyd Brown | Sixth | 20½ out |
| Thursday, June 27 |
| » Lost to Red Sox (20-47), 4-1 | Fenway Park (1-2) | 25-35 | |
| » Starters: Ad Liska vs Ed Morris | Sixth | 21½ out |
| Friday, June 28 |
| » Lost to Red Sox (21-47), 5-2 | Fenway Park (1-3) | 25-36 | Lost 2 |
| » Starters: Myles Thomas vs Jack Russell | Sixth | 22 out |
| Saturday, June 29 |
| » Lost to Red Sox (22-47), 5-2 | Fenway Park (1-4) | 25-37 | Lost 3 |
| » Starters: Bobby Burke vs Red Ruffing | Sixth | 22 out |
| Sunday, June 30 |
| » Defeated Athletics (48-17), 12-2 | Griffith Stadium (17-21) | 26-37 | |
| » Starters: Jack Quinn vs Firpo Marberry | Sixth | 21 out |
| Tuesday, July 2 |
| » Lost to Athletics (49-17), 7-4 | Shibe Park (1-6) | 26-38 | |
| » Starters: Bump Hadley vs Rube Walberg | Sixth | 23 out |
| » Lost to Athletics (50-17), 4-1 | Shibe Park (1-7) | 26-39 | Lost 2 |
| » Starters: Sam Jones vs George Earnshaw | Sixth | 23 out |
| Future Senator Chuck Stobbs is born in Wheeling, WV. |
| Wednesday, July 3 |
| » Lost to Athletics (51-17), 9-7 | Shibe Park (1-8) | 26-40 | Lost 3 |
| » Starters: Myles Thomas vs Eddie Rommel | Sixth | 24 out |
| Thursday, July 4 |
| » Lost to Yankees (42-26), 8-4 | Yankee Stadium (2-2) | 26-41 | Lost 4 |
| » Starters: Firpo Marberry vs George Pipgras | Sixth | 26 out |
| » Lost to Yankees (43-26), 14-4 | Yankee Stadium (2-3) | 26-42 | Lost 5 |
| » Starters: Lloyd Brown vs Ed Wells | Sixth | 26 out |
| Sunday, July 7 |
| » Lost to Tigers (40-36), 9-1 | Tiger Stadium (1-3) | 26-43 | Lost 6 |
| » Starters: Firpo Marberry vs Earl Whitehill | Sixth | 25½ out |
| Future Senator John Romonosky is born in Harrisburg, IL. |
| Monday, July 8 |
| » Defeated Tigers (40-37), 5-4 | Tiger Stadium (2-3) | 27-43 | |
| » Starters: Sam Jones vs George Uhle | Sixth | 26 out |
| » Lost to Tigers (41-37), 16-6 | Tiger Stadium (2-4) | 27-44 | |
| » Starters: Lloyd Brown vs Emil Yde | Sixth | 26 out |
| Tuesday, July 9 |
| » Defeated Tigers (41-38), 2-1 | Tiger Stadium (3-4) | 28-44 | |
| » Starters: Garland Braxton vs Ownie Carroll | Sixth | 25 out |
| Former Senator Pete Cassidy dies in Wilmington, DE at the age of 57. |
| Wednesday, July 10 |
| » Lost to Indians (38-37), 9-7 | League Park II (1-3) | 28-45 | |
| » Starters: Lloyd Brown vs Johnny Miljus | Sixth | 25½ out |
| Thursday, July 11 |
| » Defeated Indians (38-38), 9-3 | League Park II (2-3) | 29-45 | |
| » Starters: Firpo Marberry vs Jimmy Zinn | Sixth | 25 out |
| Friday, July 12 |
| » Lost to Indians (39-38), 3-2 | League Park II (2-4) | 29-46 | |
| » Starters: Myles Thomas vs Joe Shaute | Sixth | 26½ out |
| Saturday, July 13 |
| » Lost to Indians (40-38), 6-1 | League Park II (2-5) | 29-47 | Lost 2 |
| » Starters: Sam Jones vs Jake Miller | Sixth | 27 out |
| Sunday, July 14 |
| » Defeated White Sox (29-55), 7-1 | Comiskey Park I (3-1) | 30-47 | |
| » Starters: Garland Braxton vs Tommy Thomas | Sixth | 27 out |
| Monday, July 15 |
| » Lost to White Sox (30-55), 4-2 | Comiskey Park I (3-2) | 30-48 | |
| » Starters: Firpo Marberry vs Ed Walsh | Sixth | 27½ out |
| Tuesday, July 16 |
| » Lost to White Sox (31-55), 6-5 | Comiskey Park I (3-3) | 30-49 | Lost 2 |
| » Starters: Myles Thomas vs Bob Weiland | Sixth | 28½ out |
| Wednesday, July 17 |
| » Defeated White Sox (31-56), 6-2 | Comiskey Park I (4-3) | 31-49 | |
| » Starters: Bobby Burke vs Ted Lyons | Sixth | 27½ out |
| Thursday, July 18 |
| » Defeated Browns (49-37), 10-3 | Sportsman's Park III (2-1) | 32-49 | Won 2 |
| » Starters: Sam Jones vs George Blaeholder | Sixth | 27½ out |
| Friday, July 19 |
| » Lost to Browns (50-37), 7-3 | Sportsman's Park III (2-2) | 32-50 | |
| » Starters: Garland Braxton vs Lefty Stewart | Sixth | 28½ out |
| Saturday, July 20 |
| » Defeated Browns (50-38), 3-2 | Sportsman's Park III (3-2) | 33-50 | |
| » Starters: Firpo Marberry vs Rip Collins | Sixth | 28 out |
| » Defeated Browns (50-39), 2-1 | Sportsman's Park III (4-2) | 34-50 | Won 2 |
| » Starters: Bobby Burke vs Jack Ogden | Sixth | 28 out |
| Sunday, July 21 |
| » Lost to Browns (51-39), 8-5 | Sportsman's Park III (4-3) | 34-51 | |
| » Starters: Sam Jones vs Dolly Gray | Sixth | 29 out |
| Future Senator Jerry Snyder is born in Jenks, OK. |
| Tuesday, July 23 |
| » Lost to White Sox (36-56), 3-2 | Griffith Stadium (17-22) | 34-52 | Lost 2 |
| » Starters: Red Faber vs Garland Braxton | Sixth | 29½ out |
| Wednesday, July 24 |
| » Defeated White Sox (36-57), 3-2 | Griffith Stadium (18-22) | 35-52 | |
| » Starters: Tommy Thomas vs Bobby Burke | Sixth | 29½ out |
| Thursday, July 25 |
| » Lost to White Sox (37-57), 3-1 | Griffith Stadium (18-23) | 35-53 | |
| » Starters: Ed Walsh vs Firpo Marberry | Sixth | 30½ out |
| Friday, July 26 |
| » Lost to Indians (47-46), 4-2 | Griffith Stadium (18-24) | 35-54 | Lost 2 |
| » Starters: Jake Miller vs Sam Jones | Sixth | 31½ out |
| Saturday, July 27 |
| » Lost to Indians (48-46), 5-3 | Griffith Stadium (18-25) | 35-55 | Lost 3 |
| » Starters: Willis Hudlin vs Garland Braxton | Sixth | 32½ out |
| Sunday, July 28 |
| » Lost to Indians (49-46), 9-6 | Griffith Stadium (18-26) | 35-56 | Lost 4 |
| » Starters: Joe Shaute vs Bobby Burke | Sixth | 33 out |
| Tuesday, July 30 |
| » Defeated Browns (52-44), 11-9 | Griffith Stadium (19-26) | 36-56 | |
| » Starters: Dolly Gray vs Bump Hadley | Sixth | 32½ out |
| Wednesday, July 31 |
| » Lost to Browns (53-44), 5-1 | Griffith Stadium (19-27) | 36-57 | |
| » Starters: Lefty Stewart vs Bobby Burke | Sixth | 33½ out |
| Thursday, August 1 |
| » Defeated Browns (53-45), 13-9 | Griffith Stadium (20-27) | 37-57 | |
| » Starters: Rip Collins vs Sam Jones | Sixth | 33½ out |
| Friday, August 2 |
| » Defeated Browns (53-46), 5-3 | Griffith Stadium (21-27) | 38-57 | Won 2 |
| » Starters: Alvin Crowder vs Bump Hadley | Sixth | 33½ out |
| Sunday, August 4 |
| » Lost to Tigers (48-52), 10-5 | Griffith Stadium (21-28) | 38-58 | |
| » Starters: Earl Whitehill vs Garland Braxton | Sixth | 34½ out |
| » Lost to Tigers (49-52), 13-11 | Griffith Stadium (21-29) | 38-59 | Lost 2 |
| » Starters: George Uhle vs Bobby Burke | Sixth | 34½ out |
| Monday, August 5 |
| » Defeated Tigers (49-53), 21-5 | Griffith Stadium (22-29) | 39-59 | |
| » Starters: George Uhle vs Lloyd Brown | Sixth | 34 out |
| Former Senator Tony Brottem dies in Chicago, IL at the age of 38. |
| Tuesday, August 6 |
| » Defeated Yankees (61-37), 13-9 | Yankee Stadium (3-3) | 40-59 | Won 2 |
| » Starters: Bump Hadley vs Ed Wells | Fifth | 34 out |
| » Lost to Yankees (62-37), 8-0 | Yankee Stadium (3-4) | 40-60 | |
| » Starters: Bobby Burke vs Fred Heimach | Fifth | 34 out |
| Wednesday, August 7 |
| » Defeated Red Sox (31-71), 4-2 | Fenway Park (2-4) | 41-60 | |
| » Starters: Myles Thomas vs Danny MacFayden | Sixth | 33½ out |
| Thursday, August 8 |
| » Defeated Red Sox (31-72), 3-2 | Fenway Park (3-4) | 42-60 | Won 2 |
| » Starters: Lloyd Brown vs Milt Gaston | Fifth | 32½ out |
| Saturday, August 10 |
| » Defeated Browns (56-51), 4-2 | Sportsman's Park III (5-3) | 43-60 | Won 3 |
| » Starters: Firpo Marberry vs Lefty Stewart | Sixth | 32½ out |
| Sunday, August 11 |
| » Defeated Browns (56-52), 7-5 | Sportsman's Park III (6-3) | 44-60 | Won 4 |
| » Starters: Bobby Burke vs George Blaeholder | Sixth | 31½ out |
| Monday, August 12 |
| » Defeated Browns (56-53), 3-2 | Sportsman's Park III (7-3) | 45-60 | Won 5 |
| » Starters: Garland Braxton vs Alvin Crowder | Sixth | 31½ out |
| Tuesday, August 13 |
| » Lost to Browns (57-53), 14-2 | Sportsman's Park III (7-4) | 45-61 | |
| » Starters: Bump Hadley vs Jack Ogden | Sixth | 32½ out |
| Wednesday, August 14 |
| » Defeated White Sox (43-68), 11-3 | Comiskey Park I (5-3) | 46-61 | |
| » Starters: Myles Thomas vs Ed Walsh | Sixth | 32½ out |
| Thursday, August 15 |
| » Defeated White Sox (43-69), 9-4 | Comiskey Park I (6-3) | 47-61 | Won 2 |
| » Starters: Firpo Marberry vs Red Faber | Sixth | 32 out |
| Friday, August 16 |
| » Lost to White Sox (44-69), 8-6 | Comiskey Park I (6-4) | 47-62 | |
| » Starters: Bobby Burke vs Tommy Thomas | Sixth | 33 out |
| Saturday, August 17 |
| » Defeated White Sox (44-70), 5-2 | Comiskey Park I (7-4) | 48-62 | |
| » Starters: Lloyd Brown vs Bob Weiland | Sixth | 32 out |
| Sunday, August 18 |
| » Lost to Indians (60-53), 8-1 | League Park II (2-6) | 48-63 | |
| » Starters: Garland Braxton vs Willis Hudlin | Sixth | 32 out |
| Monday, August 19 |
| » Defeated Indians (60-54), 5-3 | League Park II (3-6) | 49-63 | |
| » Starters: Sam Jones vs Jake Miller | Sixth | 32 out |
| Tuesday, August 20 |
| » Defeated Indians (60-55), 6-2 | League Park II (4-6) | 50-63 | Won 2 |
| » Starters: Bobby Burke vs Milt Shoffner | Sixth | 31 out |
| Wednesday, August 21 |
| » Lost to Indians (61-55), 3-1 | League Park II (4-7) | 50-64 | |
| » Starters: Lloyd Brown vs Wes Ferrell | Sixth | 31 out |
| Thursday, August 22 |
| » Defeated Tigers (56-63), 6-1 | Tiger Stadium (4-4) | 51-64 | |
| » Starters: Garland Braxton vs Ownie Carroll | Sixth | 30 out |
| Friday, August 23 |
| » Defeated Tigers (56-64), 1-0 | Tiger Stadium (5-4) | 52-64 | Won 2 |
| » Starters: Sam Jones vs Earl Whitehill | Sixth | 29 out |
| Saturday, August 24 |
| » Defeated Tigers (56-65), 9-6 | Tiger Stadium (6-4) | 53-64 | Won 3 |
| » Starters: Myles Thomas vs Vic Sorrell | Sixth | 29 out |
| Sunday, August 25 |
| » Lost to Tigers (57-65), 8-7 | Tiger Stadium (6-5) | 53-65 | |
| » Starters: Bump Hadley vs Phil Page | Sixth | 29 out |
| Tuesday, August 27 |
| » Defeated Red Sox (43-79), 5-4 | Griffith Stadium (23-29) | 54-65 | |
| » Starters: Danny MacFayden vs Sam Jones | Sixth | 28 out |
| Wednesday, August 28 |
| » Defeated Red Sox (43-80), 7-4 | Griffith Stadium (24-29) | 55-65 | Won 2 |
| » Starters: Milt Gaston vs Myles Thomas | Sixth | 28 out |
| Thursday, August 29 |
| » Lost to Yankees (71-50), 5-4 | Yankee Stadium (3-5) | 55-66 | |
| » Starters: Firpo Marberry vs Herb Pennock | Sixth | 28½ out |
| » Defeated Yankees (71-51), 8-4 | Yankee Stadium (4-5) | 56-66 | |
| » Starters: Bump Hadley vs Waite Hoyt | Sixth | 28½ out |
| Saturday, August 31 |
| » Lost to Yankees (72-51), 4-0 | Yankee Stadium (4-6) | 56-67 | |
| » Starters: Garland Braxton vs Ed Wells | Sixth | 29½ out |
| » Lost to Yankees (73-51), 13-3 | Yankee Stadium (4-7) | 56-68 | Lost 2 |
| » Starters: Bobby Burke vs Roy Sherid | Sixth | 29½ out |
| Sunday, September 1 |
| » Defeated Athletics (87-41), 12-3 | Griffith Stadium (25-29) | 57-68 | |
| » Starters: Bill Shores vs Sam Jones | Sixth | 28½ out |
| Monday, September 2 |
| » Defeated Red Sox (44-84), 10-7 | Fenway Park (4-4) | 58-68 | Won 2 |
| » Starters: Myles Thomas vs Danny MacFayden | Sixth | 29½ out |
| » Lost to Red Sox (45-84), 7-2 | Fenway Park (4-5) | 58-69 | |
| » Starters: Bump Hadley vs Milt Gaston | Sixth | 29½ out |
| Tuesday, September 3 |
| » Defeated Red Sox (45-85), 10-5 | Fenway Park (5-5) | 59-69 | |
| » Starters: Firpo Marberry vs Ed Morris | Sixth | 29½ out |
| Wednesday, September 4 |
| » Lost to Red Sox (46-85), 5-1 | Fenway Park (5-6) | 59-70 | |
| » Starters: Sam Jones vs Jack Russell | Sixth | 30 out |
| Saturday, September 7 |
| » Defeated White Sox (51-78), 2-1 | Griffith Stadium (26-29) | 60-70 | |
| » Starters: Tommy Thomas vs Firpo Marberry | Sixth | 29½ out |
| Sunday, September 8 |
| » Lost to White Sox (52-78), 4-3 | Griffith Stadium (26-30) | 60-71 | |
| » Starters: Red Faber vs Myles Thomas | Sixth | 30 out |
| Monday, September 9 |
| » Lost to White Sox (53-78), 6-4 | Griffith Stadium (26-31) | 60-72 | Lost 2 |
| » Starters: Ed Walsh vs Sam Jones | Sixth | 30½ out |
| Wednesday, September 11 |
| » Defeated Indians (70-62), 5-2 | Griffith Stadium (27-31) | 61-72 | |
| » Starters: Willis Hudlin vs Firpo Marberry | Fifth | 31 out |
| Thursday, September 12 |
| » Lost to Indians (71-62), 5-1 | Griffith Stadium (27-32) | 61-73 | |
| » Starters: Jake Miller vs Myles Thomas | Sixth | 32 out |
| Friday, September 13 |
| » Defeated Indians (71-63), 4-3 | Griffith Stadium (28-32) | 62-73 | |
| » Starters: Milt Shoffner vs Sam Jones | Sixth | 32 out |
| Saturday, September 14 |
| » Lost to Indians (72-63), 4-1 | Griffith Stadium (28-33) | 62-74 | |
| » Starters: Wes Ferrell vs Lloyd Brown | Sixth | 33 out |
| Sunday, September 15 |
| » Lost to Tigers (65-73), 16-2 | Griffith Stadium (28-34) | 62-75 | Lost 2 |
| » Starters: Earl Whitehill vs Myles Thomas | Sixth | 33½ out |
| » Tied Tigers, 3-3 | Griffith Stadium (28-34) | 62-75 | |
| » Starters: George Uhle vs Firpo Marberry | Sixth | 33½ out |
| Monday, September 16 |
| » Defeated Tigers (65-74), 10-9 | Griffith Stadium (29-34) | 63-75 | |
| » Starters: Whit Wyatt vs Bump Hadley | Sixth | 32½ out |
| » Major-league debuts: Whit Wyatt (Tigers) |
| Tuesday, September 17 |
| » Defeated Tigers (65-75), 4-1 | Griffith Stadium (30-34) | 64-75 | Won 2 |
| » Starters: Vic Sorrell vs Sam Jones | Sixth | 32 out |
| Wednesday, September 18 |
| » Defeated Tigers (65-76), 2-0 | Griffith Stadium (31-34) | 65-75 | Won 3 |
| » Starters: Earl Whitehill vs Bump Hadley | Fifth | 31 out |
| » Defeated Tigers (65-77), 1-0 | Griffith Stadium (32-34) | 66-75 | Won 4 |
| » Starters: Chief Hogsett vs Lloyd Brown | Fifth | 31 out |
| » Major-league debuts: Chief Hogsett (Tigers) |
| Thursday, September 19 |
| » Defeated Browns (73-68), 2-1 | Griffith Stadium (33-34) | 67-75 | Won 5 |
| » Starters: George Blaeholder vs Firpo Marberry | Fifth | 31 out |
| Friday, September 20 |
| » Lost to Browns (74-68), 1-0 | Griffith Stadium (33-35) | 67-76 | |
| » Starters: Alvin Crowder vs Myles Thomas | Fifth | 32 out |
| Saturday, September 21 |
| » Lost to Browns (75-68), 4-3 | Griffith Stadium (33-36) | 67-77 | Lost 2 |
| » Starters: Lefty Stewart vs Sam Jones | Fourth | 33 out |
| Sunday, September 22 |
| » Defeated Athletics (100-45), 7-6 | Griffith Stadium (34-36) | 68-77 | |
| » Starters: Lefty Grove vs Bump Hadley | Fifth | 32 out |
| Future Senator Harry Bright is born in Kansas City, MO. |
| Monday, September 23 |
| » Defeated White Sox (56-88), 7-6 | Griffith Stadium (35-36) | 69-77 | Won 2 |
| » Starters: Hal McKain vs Lloyd Brown | Fifth | 31½ out |
| Thursday, September 26 |
| » Lost to Yankees (87-62), 10-3 | Griffith Stadium (35-37) | 69-78 | |
| » Starters: Ed Wells vs Bump Hadley | Fifth | 32½ out |
| Saturday, September 28 |
| » Defeated Yankees (87-63), 6-4 | Griffith Stadium (36-37) | 70-78 | |
| » Starters: Roy Sherid vs Sam Jones | Fifth | 32 out |
| » Defeated Yankees (87-64), 6-3 | Griffith Stadium (37-37) | 71-78 | Won 2 |
| » Starters: Gordon Rhodes vs Firpo Marberry | Fifth | 32 out |
| Sunday, September 29 |
| » Lost to Yankees (88-64), 3-0 | Griffith Stadium (37-38) | 71-79 | |
| » Starters: George Pipgras vs Lloyd Brown | Fifth | 32 out |
| Saturday, October 5 |
| » Lost to Red Sox (57-96), 4-3 | Griffith Stadium (37-39) | 71-80 | Lost 2 |
| » Starters: Milt Gaston vs Firpo Marberry | Fifth | 33 out |
| Sunday, October 6 |
| » Lost to Red Sox (58-96), 2-1 | Griffith Stadium (37-40) | 71-81 | Lost 3 |
| » Starters: Ed Durham vs Ad Liska | Fifth | 34 out |
| Thursday, November 14 |
| Future Senator Jimmy Piersall is born in Waterbury, CT. |
| Sunday, November 17 |
| Future Senator Norm Zauchin is born in Royal Oak, MI. |
| Wednesday, November 20 |
| Future Senator Lou Berberet is born in Long Beach, CA. |
| Saturday, December 14 |
| Future Senator Pete Whisenant is born in Asheville, NC. |
| Monday, December 23 |
| Future Senator Al Cicotte is born in Melvindale, MI. |
Game information provided by Retrosheet (www.retrosheet.org) |
