| Monday, January 23 |
| Future White Sox Chico Carrasquel is born in Caracas, Venezuela. |
| Tuesday, February 7 |
| Future White Sox Al Smith is born in Kirkwood, MO. |
| Friday, February 24 |
| Future White Sox Bubba Phillips is born in West Point, MS. |
| Friday, March 23 |
| Future White Sox Jim Lemon is born in Covington, VA. |
| Tuesday, April 10 |
| » Major-league debuts: Doug Taitt (Red Sox) |
| Wednesday, April 11 |
| » Lost to Indians (1-0), 8-2 | Comiskey Park I (0-1) | 0-1 | |
| » Starters: George Uhle vs Ted Lyons | Third | 1 out |
| » Major-league debuts: Bill Cissell and Buck Redfern (White Sox) Ed Morgan (Indians) |
| Thursday, April 12 |
| » Lost to Indians (2-0), 2-1 | Comiskey Park I (0-2) | 0-2 | Lost 2 |
| » Starters: Joe Shaute vs Tommy Thomas | Fifth | 2 out |
| Friday, April 13 |
| » Tied Indians, 1-1 | Comiskey Park I (0-2) | 0-2 | |
| » Starters: Jake Miller vs Grady Adkins | Fifth | 2½ out |
| » Major-league debuts: Grady Adkins (White Sox) |
| Sunday, April 15 |
| » Lost to Browns (4-0), 4-1 | Comiskey Park I (0-3) | 0-3 | Lost 3 |
| » Starters: Dolly Gray vs George Cox | Seventh | 3½ out |
| Monday, April 16 |
| » Defeated Browns (4-1), 7-0 | Comiskey Park I (1-3) | 1-3 | |
| » Starters: Dick Coffman vs Tommy Thomas | Third | 2½ out |
| Tuesday, April 17 |
| » Defeated Browns (4-2), 4-2 | Comiskey Park I (2-3) | 2-3 | Won 2 |
| » Starters: Lefty Stewart vs Ted Lyons | Fifth | 2 out |
| Wednesday, April 18 |
| » Lost to Indians (6-1), 7-1 | League Park II (0-1) | 2-4 | |
| » Starters: Grady Adkins vs Joe Shaute | Fifth | 3 out |
| Thursday, April 19 |
| » Lost to Indians (7-1), 9-2 | League Park II (0-2) | 2-5 | Lost 2 |
| » Starters: Charlie Barnabe vs Willis Hudlin | Fifth | 4½ out |
| Friday, April 20 |
| » Defeated Indians (7-2), 11-1 | League Park II (1-2) | 3-5 | |
| » Starters: Tommy Thomas vs Jake Miller | Fifth | 3½ out |
| Sunday, April 22 |
| » Defeated Tigers (4-8), 9-3 | Tiger Stadium (1-0) | 4-5 | Won 2 |
| » Starters: Ted Lyons vs Josh Billings | Fourth | 3½ out |
| » Major-league debuts: Vic Sorrell (Tigers) |
| Monday, April 23 |
| » Lost to Tigers (5-8), 3-0 | Tiger Stadium (1-1) | 4-6 | |
| » Starters: Sarge Connally vs Ownie Carroll | Fourth | 3½ out |
| Tuesday, April 24 |
| » Defeated Tigers (5-9), 5-4 | Tiger Stadium (2-1) | 5-6 | |
| » Starters: Tommy Thomas vs Sam Gibson | Fifth | 2½ out |
| Wednesday, April 25 |
| » Lost to Tigers (6-9), 3-2 | Tiger Stadium (2-2) | 5-7 | |
| » Starters: Grady Adkins vs Earl Whitehill | Sixth | 3 out |
| Thursday, April 26 |
| » Lost to Browns (8-7), 6-5 | Sportsman's Park III (0-1) | 5-8 | Lost 2 |
| » Starters: Ted Lyons vs George Blaeholder | Sixth | 4 out |
| Friday, April 27 |
| » Lost to Browns (9-7), 14-5 | Sportsman's Park III (0-2) | 5-9 | Lost 3 |
| » Starters: Sarge Connally vs Dolly Gray | Sixth | 5½ out |
| Saturday, April 28 |
| » Defeated Browns (9-8), 9-6 | Sportsman's Park III (1-2) | 6-9 | |
| » Starters: Tommy Thomas vs Alvin Crowder | Sixth | 5½ out |
| Sunday, April 29 |
| » Lost to Browns (10-8), 5-2 | Sportsman's Park III (1-3) | 6-10 | |
| » Starters: Grady Adkins vs Jack Ogden | Sixth | 5 out |
| Monday, April 30 |
| » Defeated Tigers (7-13), 10-6 | Comiskey Park I (3-3) | 7-10 | |
| » Starters: Earl Whitehill vs Red Faber | Fifth | 5 out |
| Tuesday, May 1 |
| » Lost to Tigers (8-13), 10-5 | Comiskey Park I (3-4) | 7-11 | |
| » Starters: Josh Billings vs Ted Blankenship | Fifth | 6 out |
| Wednesday, May 2 |
| » Lost to Tigers (9-13), 7-1 | Comiskey Park I (3-5) | 7-12 | Lost 2 |
| » Starters: Ownie Carroll vs Sarge Connally | Seventh | 6 out |
| Friday, May 4 |
| » Lost to Yankees (12-4), 10-4 | Yankee Stadium (0-1) | 7-13 | Lost 3 |
| » Starters: Tommy Thomas vs Herb Pennock | Eighth | 7 out |
| Saturday, May 5 |
| » Lost to Yankees (13-4), 7-0 | Yankee Stadium (0-2) | 7-14 | Lost 4 |
| » Starters: Ted Blankenship vs George Pipgras | Eighth | 8 out |
| Sunday, May 6 |
| » Lost to Yankees (14-4), 4-2 | Yankee Stadium (0-3) | 7-15 | Lost 5 |
| » Starters: Red Faber vs Stan Coveleski | Seventh | 9 out |
| Monday, May 7 |
| » Lost to Yankees (15-4), 8-5 | Yankee Stadium (0-4) | 7-16 | Lost 6 |
| » Starters: Tommy Thomas vs Al Shealy | Seventh | 10 out |
| Tuesday, May 8 |
| » Lost to Red Sox (7-14), 5-1 | Fenway Park (0-1) | 7-17 | Lost 7 |
| » Starters: Sarge Connally vs Ed Morris | Eighth | 10 out |
| Thursday, May 10 |
| » Defeated Red Sox (7-15), 9-2 | Fenway Park (1-1) | 8-17 | |
| » Starters: Ted Blankenship vs Danny MacFayden | Seventh | 10 out |
| Friday, May 11 |
| » Lost to Red Sox (8-15), 4-3 | Fenway Park (1-2) | 8-18 | |
| » Starters: Grady Adkins vs Red Ruffing | Eighth | 11 out |
| Saturday, May 12 |
| » Defeated Senators (9-14), 9-6 | Griffith Stadium (1-0) | 9-18 | |
| » Starters: Tommy Thomas vs Tom Zachary | Eighth | 11 out |
| Sunday, May 13 |
| » Lost to Senators (10-14), 10-3 | Griffith Stadium (1-1) | 9-19 | |
| » Starters: Charlie Barnabe vs Bump Hadley | Eighth | 12 out |
| Monday, May 14 |
| » Lost to Senators (11-14), 4-2 | Griffith Stadium (1-2) | 9-20 | Lost 2 |
| » Starters: Ted Blankenship vs Milt Gaston | Eighth | 13 out |
| Tuesday, May 15 |
| » Defeated Senators (11-15), 3-2 | Griffith Stadium (2-2) | 10-20 | |
| » Starters: Grady Adkins vs Hod Lisenbee | Seventh | 13 out |
| Thursday, May 17 |
| » Defeated Athletics (16-8), 6-5 | Shibe Park (1-0) | 11-20 | Won 2 |
| » Starters: Tommy Thomas vs Ossie Orwoll | Seventh | 13 out |
| Saturday, May 19 |
| » Lost to Athletics (17-8), 2-0 | Shibe Park (1-1) | 11-21 | |
| » Starters: Red Faber vs Lefty Grove | Seventh | 13½ out |
| Sunday, May 20 |
| » Lost to Tigers (13-23), 2-1 | Tiger Stadium (2-3) | 11-22 | Lost 2 |
| » Starters: Ted Lyons vs Elam Vangilder | Eighth | 14½ out |
| Tuesday, May 22 |
| » Defeated Indians (21-14), 4-3 | Comiskey Park I (4-5) | 12-22 | |
| » Starters: George Uhle vs Ted Blankenship | Seventh | 14½ out |
| Wednesday, May 23 |
| » Defeated Indians (21-15), 4-3 | Comiskey Park I (5-5) | 13-22 | Won 2 |
| » Starters: Jake Miller vs Grady Adkins | Sixth | 14½ out |
| Thursday, May 24 |
| » Lost to Tigers (15-24), 6-4 | Comiskey Park I (5-6) | 13-23 | |
| » Starters: Earl Whitehill vs Tommy Thomas | Seventh | 15 out |
| Friday, May 25 |
| » Defeated Tigers (15-25), 1-0 | Comiskey Park I (6-6) | 14-23 | |
| » Starters: Ken Holloway vs Red Faber | Sixth | 15½ out |
| Sunday, May 27 |
| » Defeated Tigers (15-26), 3-2 | Comiskey Park I (7-6) | 15-23 | Won 2 |
| » Starters: Elam Vangilder vs Ted Lyons | Sixth | 15½ out |
| Monday, May 28 |
| » Lost to Browns (18-22), 2-1 | Sportsman's Park III (1-4) | 15-24 | |
| » Starters: Ted Blankenship vs Boom-Boom Beck | Sixth | 16½ out |
| Wednesday, May 30 |
| » Lost to Browns (19-22), 3-1 | Sportsman's Park III (1-5) | 15-25 | Lost 2 |
| » Starters: Red Faber vs Jack Ogden | Seventh | 18 out |
| » Lost to Browns (20-22), 5-2 | Sportsman's Park III (1-6) | 15-26 | Lost 3 |
| » Starters: Tommy Thomas vs Alvin Crowder | Seventh | 18 out |
| Thursday, May 31 |
| » Defeated Browns (20-23), 7-2 | Sportsman's Park III (2-6) | 16-26 | |
| » Starters: Ted Lyons vs George Blaeholder | Seventh | 18½ out |
| » Lost to Browns (21-23), 2-1 | Sportsman's Park III (2-7) | 16-27 | |
| » Starters: Grady Adkins vs Dolly Gray | Seventh | 18½ out |
| Saturday, June 2 |
| » Lost to Athletics (26-14), 3-2 | Comiskey Park I (7-7) | 16-28 | Lost 2 |
| » Starters: Lefty Grove vs Ted Blankenship | Seventh | 19½ out |
| Sunday, June 3 |
| » Defeated Athletics (26-15), 6-5 | Comiskey Park I (8-7) | 17-28 | |
| » Starters: George Earnshaw vs Tommy Thomas | Seventh | 19½ out |
| Monday, June 4 |
| » Lost to Athletics (27-15), 6-3 | Comiskey Park I (8-8) | 17-29 | |
| » Starters: Rube Walberg vs Red Faber | Seventh | 20 out |
| Thursday, June 7 |
| » Lost to Senators (16-27), 7-5 | Comiskey Park I (8-9) | 17-30 | Lost 2 |
| » Starters: Bump Hadley vs Ted Lyons | Seventh | 21½ out |
| Saturday, June 9 |
| » Lost to Senators (17-27), 4-2 | Comiskey Park I (8-10) | 17-31 | Lost 3 |
| » Starters: Tom Zachary vs Grady Adkins | Eighth | 22½ out |
| Sunday, June 10 |
| » Defeated Yankees (39-9), 8-6 | Comiskey Park I (9-10) | 18-31 | |
| » Starters: Stan Coveleski vs Red Faber | Eighth | 21½ out |
| Monday, June 11 |
| » Defeated Yankees (39-10), 6-1 | Comiskey Park I (10-10) | 19-31 | Won 2 |
| » Starters: Herb Pennock vs Ted Blankenship | Eighth | 20½ out |
| Tuesday, June 12 |
| » Lost to Yankees (40-10), 15-7 | Comiskey Park I (10-11) | 19-32 | |
| » Starters: George Pipgras vs Grady Adkins | Eighth | 21½ out |
| Wednesday, June 13 |
| » Lost to Yankees (41-10), 8-6 | Comiskey Park I (10-12) | 19-33 | Lost 2 |
| » Starters: Waite Hoyt vs Ted Lyons | Eighth | 22½ out |
| Thursday, June 14 |
| » Defeated Red Sox (18-29), 5-4 | Comiskey Park I (11-12) | 20-33 | |
| » Starters: Red Ruffing vs Red Faber | Eighth | 22½ out |
| Friday, June 15 |
| » Lost to Red Sox (19-29), 3-1 | Comiskey Park I (11-13) | 20-34 | |
| » Starters: Danny MacFayden vs Tommy Thomas | Eighth | 22½ out |
| Saturday, June 16 |
| » Lost to Red Sox (20-29), 10-5 | Comiskey Park I (11-14) | 20-35 | Lost 2 |
| » Starters: Ed Morris vs Ted Blankenship | Eighth | 22½ out |
| Wednesday, June 20 |
| » Defeated Indians (26-32), 6-4 | League Park II (2-2) | 21-35 | |
| » Starters: Ted Lyons vs Dutch Levsen | Eighth | 23 out |
| » Lost to Indians (27-32), 4-3 | League Park II (2-3) | 21-36 | |
| » Starters: Red Faber vs George Grant | Eighth | 23 out |
| Thursday, June 21 |
| » Lost to Indians (28-32), 4-2 | League Park II (2-4) | 21-37 | Lost 2 |
| » Starters: Tommy Thomas vs Jake Miller | Eighth | 23½ out |
| » Defeated Indians (28-33), 4-3 | League Park II (3-4) | 22-37 | |
| » Starters: Grady Adkins vs Joe Shaute | Eighth | 23½ out |
| Friday, June 22 |
| » Defeated Indians (28-34), 7-4 | League Park II (4-4) | 23-37 | Won 2 |
| » Starters: Ted Blankenship vs George Uhle | Eighth | 23 out |
| Saturday, June 23 |
| » Defeated Tigers (24-39), 6-4 | Tiger Stadium (3-3) | 24-37 | Won 3 |
| » Starters: Red Faber vs Sam Gibson | Seventh | 21½ out |
| Sunday, June 24 |
| » Lost to Tigers (25-39), 6-0 | Tiger Stadium (3-4) | 24-38 | |
| » Starters: Ted Lyons vs Ownie Carroll | Eighth | 22½ out |
| Monday, June 25 |
| » Defeated Tigers (25-40), 8-6 | Tiger Stadium (4-4) | 25-38 | |
| » Starters: Tommy Thomas vs Earl Whitehill | Seventh | 22 out |
| Tuesday, June 26 |
| » Defeated Tigers (25-41), 5-2 | Tiger Stadium (5-4) | 26-38 | Won 2 |
| » Starters: Grady Adkins vs Ken Holloway | Seventh | 21½ out |
| Thursday, June 28 |
| » Defeated Indians (30-37), 3-2 | Comiskey Park I (12-14) | 27-38 | Won 3 |
| » Starters: George Uhle vs Ted Blankenship | Seventh | 22 out |
| Friday, June 29 |
| » Lost to Indians (31-37), 9-8 | Comiskey Park I (12-15) | 27-39 | |
| » Starters: George Grant vs Red Faber | Seventh | 22 out |
| Saturday, June 30 |
| » Lost to Indians (32-37), 8-1 | Comiskey Park I (12-16) | 27-40 | Lost 2 |
| » Starters: Joe Shaute vs Ted Lyons | Seventh | 23 out |
| » Defeated Indians (32-38), 6-2 | Comiskey Park I (13-16) | 28-40 | |
| » Starters: Dutch Levsen vs Tommy Thomas | Seventh | 23 out |
| Sunday, July 1 |
| » Lost to Indians (33-38), 5-2 | Comiskey Park I (13-17) | 28-41 | |
| » Starters: Willis Hudlin vs Grady Adkins | Seventh | 24½ out |
| Monday, July 2 |
| » Defeated Browns (37-34), 7-1 | Comiskey Park I (14-17) | 29-41 | |
| » Starters: Dolly Gray vs Ted Blankenship | Seventh | 23 out |
| » Defeated Browns (37-35), 9-8 | Comiskey Park I (15-17) | 30-41 | Won 2 |
| » Starters: George Blaeholder vs Sarge Connally | Seventh | 23 out |
| Tuesday, July 3 |
| » Defeated Browns (37-36), 8-7 | Comiskey Park I (16-17) | 31-41 | Won 3 |
| » Starters: Lefty Stewart vs George Cox | Seventh | 23 out |
| Wednesday, July 4 |
| » Lost to Browns (38-36), 11-8 | Comiskey Park I (16-18) | 31-42 | |
| » Starters: Alvin Crowder vs Ed Walsh | Sixth | 23 out |
| » Defeated Browns (38-37), 1-0 | Comiskey Park I (17-18) | 32-42 | |
| » Starters: Jack Ogden vs Tommy Thomas | Sixth | 23 out |
| » Major-league debuts: Ed Walsh (White Sox) |
| Friday, July 6 |
| » Defeated Senators (33-42), 9-8 | Griffith Stadium (3-2) | 33-42 | Won 2 |
| » Manager: Lena Blackburne |
| » Starters: Red Faber vs Milt Gaston | Fifth | 22½ out |
| Saturday, July 7 |
| » Lost to Senators (34-42), 9-1 | Griffith Stadium (3-3) | 33-43 | |
| » Starters: Ted Blankenship vs Garland Braxton | Sixth | 24 out |
| Sunday, July 8 |
| » Defeated Senators (34-43), 13-7 | Griffith Stadium (4-3) | 34-43 | |
| » Starters: Ted Lyons vs Bump Hadley | Fifth | 22½ out |
| Monday, July 9 |
| » Defeated Senators (34-44), 3-1 | Griffith Stadium (5-3) | 35-43 | Won 2 |
| » Starters: Tommy Thomas vs Sam Jones | Fifth | 22 out |
| Wednesday, July 11 |
| » Lost to Athletics (47-32), 10-3 | Shibe Park (1-2) | 35-44 | |
| » Starters: Ted Blankenship vs Lefty Grove | Fifth | 22 out |
| » Defeated Athletics (47-33), 5-1 | Shibe Park (2-2) | 36-44 | |
| » Starters: Red Faber vs George Earnshaw | Fifth | 22 out |
| Thursday, July 12 |
| » Defeated Athletics (47-34), 4-3 | Shibe Park (3-2) | 37-44 | Won 2 |
| » Starters: Ted Lyons vs Rube Walberg | Fifth | 21½ out |
| » Lost to Athletics (48-34), 5-2 | Shibe Park (3-3) | 37-45 | |
| » Starters: Grady Adkins vs Eddie Rommel | Fifth | 21½ out |
| Saturday, July 14 |
| » Defeated Red Sox (33-46), 11-4 | Fenway Park (2-2) | 38-45 | |
| » Starters: Tommy Thomas vs Jack Russell | Fourth | 20½ out |
| » Defeated Red Sox (33-47), 11-2 | Fenway Park (3-2) | 39-45 | Won 2 |
| » Starters: Ed Walsh vs Ed Morris | Fourth | 20½ out |
| Monday, July 16 |
| » Defeated Red Sox (33-48), 4-0 | Fenway Park (4-2) | 40-45 | Won 3 |
| » Starters: Red Faber vs Red Ruffing | Fourth | 21½ out |
| » Defeated Red Sox (33-49), 9-1 | Fenway Park (5-2) | 41-45 | Won 4 |
| » Starters: Ted Blankenship vs Slim Harriss | Fourth | 21½ out |
| Tuesday, July 17 |
| » Lost to Red Sox (34-49), 9-6 | Fenway Park (5-3) | 41-46 | |
| » Starters: Grady Adkins vs Danny MacFayden | Fourth | 22½ out |
| Wednesday, July 18 |
| » Lost to Yankees (64-23), 9-8 | Yankee Stadium (0-5) | 41-47 | Lost 2 |
| » Starters: Ted Lyons vs Waite Hoyt | Fourth | 23½ out |
| Thursday, July 19 |
| » Lost to Yankees (65-23), 6-4 | Yankee Stadium (0-6) | 41-48 | Lost 3 |
| » Starters: Tommy Thomas vs Herb Pennock | Fourth | 24½ out |
| Saturday, July 21 |
| » Lost to Yankees (66-23), 2-0 | Yankee Stadium (0-7) | 41-49 | Lost 4 |
| » Starters: Ed Walsh vs George Pipgras | Fourth | 25½ out |
| Sunday, July 22 |
| » Defeated Yankees (66-24), 6-4 | Yankee Stadium (1-7) | 42-49 | |
| » Starters: Red Faber vs Hank Johnson | Fourth | 24½ out |
| Wednesday, July 25 |
| » Lost to Athletics (57-36), 16-0 | Comiskey Park I (17-19) | 42-50 | |
| » Starters: Howard Ehmke vs Ted Lyons | Fourth | 24½ out |
| » Lost to Athletics (58-36), 8-7 | Comiskey Park I (17-20) | 42-51 | Lost 2 |
| » Starters: George Earnshaw vs Ted Blankenship | Fourth | 24½ out |
| Thursday, July 26 |
| » Lost to Athletics (59-36), 5-1 | Comiskey Park I (17-21) | 42-52 | Lost 3 |
| » Starters: Lefty Grove vs Tommy Thomas | Fifth | 25 out |
| Friday, July 27 |
| » Lost to Athletics (60-36), 7-4 | Comiskey Park I (17-22) | 42-53 | Lost 4 |
| » Starters: Jack Quinn vs Ed Walsh | Sixth | 25½ out |
| Saturday, July 28 |
| » Lost to Senators (44-54), 8-5 | Comiskey Park I (17-23) | 42-54 | Lost 5 |
| » Starters: Lloyd Brown vs Red Faber | Fifth | 26½ out |
| » Lost to Senators (45-54), 4-2 | Comiskey Park I (17-24) | 42-55 | Lost 6 |
| » Starters: Bobby Burke vs Ted Blankenship | Fifth | 26½ out |
| Sunday, July 29 |
| » Lost to Senators (46-54), 8-3 | Comiskey Park I (17-25) | 42-56 | Lost 7 |
| » Starters: Sam Jones vs Ted Lyons | Sixth | 26 out |
| » Defeated Senators (46-55), 5-1 | Comiskey Park I (18-25) | 43-56 | |
| » Starters: Bump Hadley vs Grady Adkins | Sixth | 26 out |
| Future White Sox Ken Landenberger is born in Lyndhurst, OH. |
| Monday, July 30 |
| » Defeated Senators (46-56), 6-0 | Comiskey Park I (19-25) | 44-56 | Won 2 |
| » Starters: Garland Braxton vs Tommy Thomas | Sixth | 25 out |
| Tuesday, July 31 |
| » Defeated Senators (46-57), 7-5 | Comiskey Park I (20-25) | 45-56 | Won 3 |
| » Starters: Milt Gaston vs Ted Blankenship | Sixth | 25 out |
| Wednesday, August 1 |
| » Defeated Red Sox (38-61), 4-2 | Comiskey Park I (21-25) | 46-56 | Won 4 |
| » Starters: Slim Harriss vs Red Faber | Fourth | 24½ out |
| » Defeated Red Sox (38-62), 7-3 | Comiskey Park I (22-25) | 47-56 | Won 5 |
| » Starters: Marty Griffin vs Ed Walsh | Fourth | 24½ out |
| Thursday, August 2 |
| » Defeated Red Sox (38-63), 6-3 | Comiskey Park I (23-25) | 48-56 | Won 6 |
| » Starters: Danny MacFayden vs Ted Lyons | Fourth | 23½ out |
| Friday, August 3 |
| » Lost to Red Sox (39-63), 3-1 | Comiskey Park I (23-26) | 48-57 | |
| » Starters: Ed Morris vs Tommy Thomas | Fourth | 23½ out |
| Saturday, August 4 |
| » Lost to Yankees (72-33), 8-6 | Comiskey Park I (23-27) | 48-58 | Lost 2 |
| » Starters: George Pipgras vs Grady Adkins | Fifth | 24½ out |
| Sunday, August 5 |
| » Defeated Yankees (72-34), 5-4 | Comiskey Park I (24-27) | 49-58 | |
| » Starters: Hank Johnson vs Ed Walsh | Fifth | 23½ out |
| Monday, August 6 |
| » Defeated Yankees (72-35), 5-4 | Comiskey Park I (25-27) | 50-58 | Won 2 |
| » Starters: Waite Hoyt vs Red Faber | Fourth | 22½ out |
| Tuesday, August 7 |
| » Lost to Yankees (73-35), 6-3 | Comiskey Park I (25-28) | 50-59 | |
| » Starters: Herb Pennock vs Ted Lyons | Fourth | 23½ out |
| Friday, August 10 |
| » Defeated Browns (57-55), 5-3 | Comiskey Park I (26-28) | 51-59 | |
| » Starters: Lefty Stewart vs Ted Blankenship | Fourth | 24 out |
| Saturday, August 11 |
| » Lost to Browns (58-55), 4-2 | Comiskey Park I (26-29) | 51-60 | |
| » Starters: Dolly Gray vs Tommy Thomas | Fourth | 25 out |
| Sunday, August 12 |
| » Lost to Browns (59-55), 7-0 | Comiskey Park I (26-30) | 51-61 | Lost 2 |
| » Starters: Alvin Crowder vs Ed Walsh | Fourth | 26 out |
| » Major-league debuts: Karl Swanson (White Sox) |
| Tuesday, August 14 |
| » Defeated Yankees (77-36), 5-2 | Yankee Stadium (2-7) | 52-61 | |
| » Starters: Grady Adkins vs Fred Heimach | Fourth | 25 out |
| Wednesday, August 15 |
| » Defeated Yankees (77-37), 8-4 | Yankee Stadium (3-7) | 53-61 | Won 2 |
| » Starters: Red Faber vs George Pipgras | Fourth | 24 out |
| » Major-league debuts: Bill Dickey (Yankees) |
| Thursday, August 16 |
| » Lost to Yankees (78-37), 11-1 | Yankee Stadium (3-8) | 53-62 | |
| » Starters: Ted Blankenship vs Waite Hoyt | Fifth | 25 out |
| Friday, August 17 |
| » Lost to Red Sox (42-73), 4-3 | Fenway Park (5-4) | 53-63 | Lost 2 |
| » Starters: Ted Lyons vs Jack Russell | Fifth | 25½ out |
| Saturday, August 18 |
| » Lost to Red Sox (43-73), 3-1 | Fenway Park (5-5) | 53-64 | Lost 3 |
| » Starters: Tommy Thomas vs Ed Morris | Fifth | 26½ out |
| Monday, August 20 |
| » Defeated Red Sox (43-74), 6-4 | Fenway Park (6-5) | 54-64 | |
| » Starters: Red Faber vs Red Ruffing | Fifth | 26 out |
| » Major-league debuts: Art Shires (White Sox) |
| Tuesday, August 21 |
| » Defeated Senators (53-67), 3-1 | Griffith Stadium (6-3) | 55-64 | Won 2 |
| » Starters: Grady Adkins vs Garland Braxton | Fourth | 26 out |
| Wednesday, August 22 |
| » Lost to Senators (54-67), 2-0 | Griffith Stadium (6-4) | 55-65 | |
| » Starters: Ed Walsh vs Bump Hadley | Fourth | 26½ out |
| Thursday, August 23 |
| » Lost to Senators (55-67), 4-3 | Griffith Stadium (6-5) | 55-66 | Lost 2 |
| » Starters: Ted Blankenship vs Firpo Marberry | Fifth | 27 out |
| Saturday, August 25 |
| » Defeated Athletics (78-44), 9-3 | Shibe Park (4-3) | 56-66 | |
| » Starters: Ted Lyons vs Howard Ehmke | Fourth | 26 out |
| » Lost to Athletics (79-44), 13-4 | Shibe Park (4-4) | 56-67 | |
| » Starters: Red Faber vs Eddie Rommel | Fourth | 26 out |
| Future White Sox Darrell Johnson is born in Horace, NE. |
| Tuesday, August 28 |
| » Lost to Athletics (80-44), 1-0 | Shibe Park (4-5) | 56-68 | Lost 2 |
| » Starters: Tommy Thomas vs Lefty Grove | Fifth | 28 out |
| » Lost to Athletics (81-44), 4-3 | Shibe Park (4-6) | 56-69 | Lost 3 |
| » Starters: Grady Adkins vs Jack Quinn | Fifth | 28 out |
| Wednesday, August 29 |
| » Lost to Athletics (82-44), 6-2 | Shibe Park (4-7) | 56-70 | Lost 4 |
| » Starters: Ted Lyons vs Rube Walberg | Seventh | 28½ out |
| Saturday, September 1 |
| » Lost to Indians (59-72), 6-2 | Comiskey Park I (26-31) | 56-71 | Lost 5 |
| » Starters: Johnny Miljus vs Red Faber | Seventh | 29 out |
| Sunday, September 2 |
| » Defeated Indians (59-73), 3-1 | Comiskey Park I (27-31) | 57-71 | |
| » Starters: Jake Miller vs Tommy Thomas | Seventh | 28 out |
| Monday, September 3 |
| » Defeated Tigers (59-73), 5-2 | Comiskey Park I (28-31) | 58-71 | Won 2 |
| » Starters: Vic Sorrell vs Grady Adkins | Fifth | 27 out |
| » Defeated Tigers (59-74), 7-5 | Comiskey Park I (29-31) | 59-71 | Won 3 |
| » Starters: Sam Gibson vs Ted Blankenship | Fifth | 27 out |
| Tuesday, September 4 |
| » Defeated Tigers (59-75), 3-2 | Comiskey Park I (30-31) | 60-71 | Won 4 |
| » Starters: Ownie Carroll vs Ted Lyons | Fourth | 26 out |
| » Defeated Tigers (59-76), 3-2 | Comiskey Park I (31-31) | 61-71 | Won 5 |
| » Starters: Ken Holloway vs Red Faber | Fourth | 26 out |
| Wednesday, September 5 |
| » Lost to Tigers (60-76), 10-2 | Comiskey Park I (31-32) | 61-72 | |
| » Starters: Lil Stoner vs Ed Walsh | Fifth | 26½ out |
| Thursday, September 6 |
| » Defeated Indians (59-77), 2-1 | League Park II (5-4) | 62-72 | |
| » Starters: Tommy Thomas vs Johnny Miljus | Fourth | 26 out |
| Saturday, September 8 |
| » Defeated Indians (59-78), 8-7 | League Park II (6-4) | 63-72 | Won 2 |
| » Starters: Grady Adkins vs Willie Underhill | Fourth | 25½ out |
| Sunday, September 9 |
| » Defeated Indians (59-79), 10-1 | League Park II (7-4) | 64-72 | Won 3 |
| » Starters: Ted Lyons vs Willis Hudlin | Fourth | 25½ out |
| Monday, September 10 |
| » Defeated Tigers (61-78), 6-4 | Tiger Stadium (6-4) | 65-72 | Won 4 |
| » Starters: Red Faber vs Sam Gibson | Fourth | 25 out |
| Tuesday, September 11 |
| » Lost to Tigers (62-78), 7-6 | Tiger Stadium (6-5) | 65-73 | |
| » Starters: Tommy Thomas vs Ownie Carroll | Fourth | 26 out |
| Thursday, September 13 |
| » Lost to Browns (77-62), 6-4 | Sportsman's Park III (2-8) | 65-74 | Lost 2 |
| » Starters: Grady Adkins vs Jack Ogden | Fourth | 26 out |
| Friday, September 14 |
| » Defeated Browns (77-63), 5-4 | Sportsman's Park III (3-8) | 66-74 | |
| » Starters: Ted Lyons vs Ed Strelecki | Fourth | 25½ out |
| Saturday, September 15 |
| » Defeated Red Sox (49-91), 4-3 | Comiskey Park I (32-32) | 67-74 | Won 2 |
| » Starters: Red Ruffing vs Red Faber | Fourth | 24½ out |
| Sunday, September 16 |
| » Defeated Red Sox (49-92), 7-1 | Comiskey Park I (33-32) | 68-74 | Won 3 |
| » Starters: Danny MacFayden vs Tommy Thomas | Fourth | 25 out |
| » Lost to Red Sox (50-92), 2-0 | Comiskey Park I (33-33) | 68-75 | |
| » Starters: Slim Harriss vs Grady Adkins | Fourth | 25 out |
| Future White Sox Vito Valentinetti is born in West New York, NJ. |
| Monday, September 17 |
| » Lost to Red Sox (51-92), 6-3 | Comiskey Park I (33-34) | 68-76 | Lost 2 |
| » Starters: Jack Russell vs Ted Lyons | Fifth | 26 out |
| Thursday, September 20 |
| » Defeated Yankees (94-50), 4-3 | Comiskey Park I (34-34) | 69-76 | |
| » Starters: George Pipgras vs Red Faber | Fourth | 25½ out |
| Friday, September 21 |
| » Lost to Yankees (95-50), 5-2 | Comiskey Park I (34-35) | 69-77 | |
| » Starters: Tom Zachary vs Grady Adkins | Fifth | 26½ out |
| Saturday, September 22 |
| » Defeated Yankees (95-51), 5-2 | Comiskey Park I (35-35) | 70-77 | |
| » Starters: Hank Johnson vs Tommy Thomas | Fifth | 25½ out |
| Sunday, September 23 |
| » Defeated Senators (71-77), 8-3 | Comiskey Park I (36-35) | 71-77 | Won 2 |
| » Starters: Firpo Marberry vs Ted Lyons | Fourth | 25½ out |
| Monday, September 24 |
| » Lost to Senators (72-77), 8-4 | Comiskey Park I (36-36) | 71-78 | |
| » Starters: Bobby Burke vs Grady Adkins | Fifth | 25½ out |
| Tuesday, September 25 |
| » Lost to Senators (73-77), 3-0 | Comiskey Park I (36-37) | 71-79 | Lost 2 |
| » Starters: Sam Jones vs Red Faber | Fifth | 26½ out |
| Thursday, September 27 |
| » Lost to Athletics (96-54), 5-3 | Comiskey Park I (36-38) | 71-80 | Lost 3 |
| » Starters: Lefty Grove vs Tommy Thomas | Fifth | 28 out |
| Friday, September 28 |
| » Lost to Athletics (97-54), 7-5 | Comiskey Park I (36-39) | 71-81 | Lost 4 |
| » Starters: Jack Quinn vs Grady Adkins | Fifth | 29 out |
| Saturday, September 29 |
| » Lost to Athletics (98-54), 5-4 | Comiskey Park I (36-40) | 71-82 | Lost 5 |
| » Starters: George Earnshaw vs Ed Walsh | Fifth | 29 out |
| Sunday, September 30 |
| » Defeated Athletics (98-55), 1-0 | Comiskey Park I (37-40) | 72-82 | |
| » Starters: Carroll Yerkes vs Bob Weiland | Fifth | 29 out |
| Tuesday, November 6 |
| Future White Sox Bill Wilson is born in Central City, NE. |
| Sunday, December 9 |
| Future White Sox Joe DeMaestri is born in San Francisco, CA. |
Game information provided by Retrosheet (www.retrosheet.org) |