| Tuesday, January 10 |
| Future Tiger Jack Dittmer is born in Elkader, IA. |
| Monday, January 16 |
| Former Tiger Claude Rossman dies in Poughkeepsie, NY at the age of 47. |
| Wednesday, February 1 |
| Former Tiger Hughie Jennings dies in Scranton, PA at the age of 59. |
| Monday, February 20 |
| Future Tiger Roy Face is born in Stephentown, NY. |
| Friday, February 24 |
| Future Tiger Bubba Phillips is born in West Point, MS. |
| Tuesday, April 10 |
| » Major-league debuts: Doug Taitt (Red Sox) |
| Wednesday, April 11 |
| » Lost to Browns (1-0), 4-1 | Tiger Stadium (0-1) | 0-1 | |
| » Starters: Dolly Gray vs Josh Billings | Third | 1 out |
| Thursday, April 12 |
| » Lost to Browns (2-0), 7-2 | Tiger Stadium (0-2) | 0-2 | Lost 2 |
| » Starters: Jack Ogden vs Earl Whitehill | Fifth | 2 out |
| Friday, April 13 |
| » Lost to Browns (3-0), 4-3 | Tiger Stadium (0-3) | 0-3 | Lost 3 |
| » Starters: Alvin Crowder vs Sam Gibson | Sixth | 3 out |
| » Major-league debuts: Bill Sweeney (Tigers) |
| Saturday, April 14 |
| » Lost to Indians (3-0), 8-6 | Tiger Stadium (0-4) | 0-4 | Lost 4 |
| » Starters: Willis Hudlin vs Lil Stoner | Sixth | 3½ out |
| Sunday, April 15 |
| » Defeated Indians (3-1), 8-2 | Tiger Stadium (1-4) | 1-4 | |
| » Starters: Garland Buckeye vs Josh Billings | Fifth | 3½ out |
| Monday, April 16 |
| » Lost to Indians (4-1), 5-4 | Tiger Stadium (1-5) | 1-5 | |
| » Starters: George Uhle vs Earl Whitehill | Fifth | 3½ out |
| Tuesday, April 17 |
| » Lost to Indians (5-1), 6-4 | Tiger Stadium (1-6) | 1-6 | Lost 2 |
| » Starters: George Grant vs Sam Gibson | Seventh | 4 out |
| Wednesday, April 18 |
| » Defeated Browns (4-3), 4-1 | Sportsman's Park III (1-0) | 2-6 | |
| » Starters: Ownie Carroll vs George Blaeholder | Sixth | 4 out |
| Thursday, April 19 |
| » Defeated Browns (4-4), 9-8 | Sportsman's Park III (2-0) | 3-6 | Won 2 |
| » Starters: Josh Billings vs Dolly Gray | Fourth | 4½ out |
| Friday, April 20 |
| » Defeated Browns (4-5), 3-0 | Sportsman's Park III (3-0) | 4-6 | Won 3 |
| » Starters: Earl Whitehill vs Jack Ogden | Fourth | 3½ out |
| Saturday, April 21 |
| » Lost to Browns (5-5), 5-2 | Sportsman's Park III (3-1) | 4-7 | |
| » Starters: Charlie Sullivan vs Alvin Crowder | Sixth | 4 out |
| » Major-league debuts: Charlie Sullivan (Tigers) |
| Sunday, April 22 |
| » Lost to White Sox (4-5), 9-3 | Tiger Stadium (1-7) | 4-8 | Lost 2 |
| » Starters: Ted Lyons vs Josh Billings | Seventh | 5 out |
| » Major-league debuts: Vic Sorrell (Tigers) |
| Monday, April 23 |
| » Defeated White Sox (4-6), 3-0 | Tiger Stadium (2-7) | 5-8 | |
| » Starters: Sarge Connally vs Ownie Carroll | Fifth | 4 out |
| Tuesday, April 24 |
| » Lost to White Sox (5-6), 5-4 | Tiger Stadium (2-8) | 5-9 | |
| » Starters: Tommy Thomas vs Sam Gibson | Eighth | 4 out |
| Wednesday, April 25 |
| » Defeated White Sox (5-7), 3-2 | Tiger Stadium (3-8) | 6-9 | |
| » Starters: Grady Adkins vs Earl Whitehill | Seventh | 3½ out |
| Thursday, April 26 |
| » Lost to Indians (10-4), 6-1 | League Park II (0-1) | 6-10 | |
| » Starters: Vic Sorrell vs George Grant | Seventh | 4½ out |
| Friday, April 27 |
| » Lost to Indians (11-4), 10-6 | League Park II (0-2) | 6-11 | Lost 2 |
| » Starters: Josh Billings vs George Uhle | Seventh | 6 out |
| Saturday, April 28 |
| » Lost to Indians (12-4), 6-3 | League Park II (0-3) | 6-12 | Lost 3 |
| » Starters: Ownie Carroll vs Joe Shaute | Seventh | 7 out |
| Sunday, April 29 |
| » Defeated Indians (12-5), 7-6 | League Park II (1-3) | 7-12 | |
| » Starters: Sam Gibson vs Jake Miller | Seventh | 5½ out |
| Monday, April 30 |
| » Lost to White Sox (7-10), 10-6 | Comiskey Park I (0-1) | 7-13 | |
| » Starters: Earl Whitehill vs Red Faber | Seventh | 6½ out |
| Tuesday, May 1 |
| » Defeated White Sox (7-11), 10-5 | Comiskey Park I (1-1) | 8-13 | |
| » Starters: Josh Billings vs Ted Blankenship | Sixth | 6½ out |
| Wednesday, May 2 |
| » Defeated White Sox (7-12), 7-1 | Comiskey Park I (2-1) | 9-13 | Won 2 |
| » Starters: Ownie Carroll vs Sarge Connally | Fifth | 5½ out |
| Friday, May 4 |
| » Lost to Athletics (8-5), 10-5 | Shibe Park (0-1) | 9-14 | |
| » Starters: Earl Whitehill vs Jack Quinn | Sixth | 6½ out |
| Saturday, May 5 |
| » Lost to Athletics (9-5), 6-5 | Shibe Park (0-2) | 9-15 | Lost 2 |
| » Starters: Sam Gibson vs Rube Walberg | Sixth | 7½ out |
| Sunday, May 6 |
| » Defeated Red Sox (6-13), 3-0 | Tiger Stadium (4-8) | 10-15 | |
| » Starters: Merle Settlemire vs Josh Billings | Sixth | 7½ out |
| Monday, May 7 |
| » Lost to Athletics (10-5), 10-0 | Shibe Park (0-3) | 10-16 | |
| » Starters: Ownie Carroll vs Lefty Grove | Sixth | 8½ out |
| Tuesday, May 8 |
| » Defeated Senators (8-12), 12-2 | Griffith Stadium (1-0) | 11-16 | |
| » Starters: Lil Stoner vs Firpo Marberry | Fifth | 7½ out |
| Thursday, May 10 |
| » Defeated Senators (8-13), 6-5 | Griffith Stadium (2-0) | 12-16 | Won 2 |
| » Starters: Earl Whitehill vs Lloyd Brown | Fifth | 7½ out |
| Friday, May 11 |
| » Lost to Senators (9-13), 9-5 | Griffith Stadium (2-1) | 12-17 | |
| » Starters: Josh Billings vs Sam Jones | Fifth | 8½ out |
| Saturday, May 12 |
| » Lost to Yankees (18-5), 8-7 | Yankee Stadium (0-1) | 12-18 | Lost 2 |
| » Starters: Ownie Carroll vs Stan Coveleski | Fifth | 9½ out |
| Sunday, May 13 |
| » Lost to Yankees (19-5), 7-2 | Yankee Stadium (0-2) | 12-19 | Lost 3 |
| » Starters: Sam Gibson vs Herb Pennock | Sixth | 10½ out |
| Monday, May 14 |
| » Lost to Yankees (20-5), 7-5 | Yankee Stadium (0-3) | 12-20 | Lost 4 |
| » Starters: Charlie Sullivan vs George Pipgras | Seventh | 11½ out |
| Tuesday, May 15 |
| » Lost to Yankees (21-5), 12-8 | Yankee Stadium (0-4) | 12-21 | Lost 5 |
| » Starters: Earl Whitehill vs Waite Hoyt | Sixth | 12½ out |
| Wednesday, May 16 |
| » Lost to Red Sox (12-15), 5-4 | Fenway Park (0-1) | 12-22 | Lost 6 |
| » Starters: Vic Sorrell vs Herb Bradley | Seventh | 13 out |
| Future Tiger Billy Martin is born in Berkeley, CA. |
| Thursday, May 17 |
| » Lost to Red Sox (13-15), 5-3 | Fenway Park (0-2) | 12-23 | Lost 7 |
| » Starters: Josh Billings vs Jack Russell | Eighth | 14 out |
| Sunday, May 20 |
| » Defeated White Sox (11-22), 2-1 | Tiger Stadium (5-8) | 13-23 | |
| » Starters: Ted Lyons vs Elam Vangilder | Seventh | 14 out |
| Tuesday, May 22 |
| » Defeated Browns (14-20), 6-3 | Tiger Stadium (6-8) | 14-23 | Won 2 |
| » Starters: Jack Ogden vs Vic Sorrell | Sixth | 14 out |
| Wednesday, May 23 |
| » Lost to Browns (15-20), 8-3 | Tiger Stadium (6-9) | 14-24 | |
| » Starters: George Blaeholder vs Josh Billings | Seventh | 15 out |
| Thursday, May 24 |
| » Defeated White Sox (13-23), 6-4 | Comiskey Park I (3-1) | 15-24 | |
| » Starters: Earl Whitehill vs Tommy Thomas | Sixth | 14½ out |
| Friday, May 25 |
| » Lost to White Sox (14-23), 1-0 | Comiskey Park I (3-2) | 15-25 | |
| » Starters: Ken Holloway vs Red Faber | Seventh | 16 out |
| Sunday, May 27 |
| » Lost to White Sox (15-23), 3-2 | Comiskey Park I (3-3) | 15-26 | Lost 2 |
| » Starters: Elam Vangilder vs Ted Lyons | Seventh | 17 out |
| Wednesday, May 30 |
| » Defeated Indians (23-18), 4-3 | League Park II (2-3) | 16-26 | |
| » Starters: Earl Whitehill vs Jake Miller | Sixth | 17 out |
| » Defeated Indians (23-19), 6-5 | League Park II (3-3) | 17-26 | Won 2 |
| » Starters: Ken Holloway vs Willis Hudlin | Sixth | 17 out |
| Thursday, May 31 |
| » Defeated Indians (23-20), 9-4 | League Park II (4-3) | 18-26 | Won 3 |
| » Starters: Sam Gibson vs Joe Shaute | Fifth | 17 out |
| Friday, June 1 |
| » Defeated Indians (23-21), 5-4 | League Park II (5-3) | 19-26 | Won 4 |
| » Starters: Josh Billings vs George Uhle | Fifth | 16½ out |
| Saturday, June 2 |
| » Lost to Yankees (35-8), 5-2 | Tiger Stadium (6-10) | 19-27 | |
| » Starters: George Pipgras vs Elam Vangilder | Fifth | 17½ out |
| Sunday, June 3 |
| » Lost to Yankees (36-8), 7-2 | Tiger Stadium (6-11) | 19-28 | Lost 2 |
| » Starters: Waite Hoyt vs Earl Whitehill | Sixth | 18½ out |
| Thursday, June 7 |
| » Defeated Red Sox (16-24), 5-2 | Tiger Stadium (7-11) | 20-28 | |
| » Starters: Jack Russell vs Ownie Carroll | Fourth | 19 out |
| Saturday, June 9 |
| » Lost to Red Sox (17-24), 11-4 | Tiger Stadium (7-12) | 20-29 | |
| » Starters: Ed Morris vs Elam Vangilder | Fifth | 19½ out |
| » Defeated Red Sox (17-25), 3-1 | Tiger Stadium (8-12) | 21-29 | |
| » Starters: Merle Settlemire vs Earl Whitehill | Fifth | 19½ out |
| Sunday, June 10 |
| » Defeated Athletics (28-19), 9-3 | Tiger Stadium (9-12) | 22-29 | Won 2 |
| » Starters: Jack Quinn vs Vic Sorrell | Fifth | 18½ out |
| Monday, June 11 |
| » Lost to Athletics (29-19), 4-2 | Tiger Stadium (9-13) | 22-30 | |
| » Starters: Ossie Orwoll vs Sam Gibson | Fifth | 18½ out |
| Tuesday, June 12 |
| » Lost to Athletics (30-19), 3-2 | Tiger Stadium (9-14) | 22-31 | Lost 2 |
| » Starters: Howard Ehmke vs Ownie Carroll | Sixth | 19½ out |
| Wednesday, June 13 |
| » Lost to Athletics (31-19), 12-5 | Tiger Stadium (9-15) | 22-32 | Lost 3 |
| » Starters: Jack Quinn vs Josh Billings | Sixth | 20½ out |
| Thursday, June 14 |
| » Lost to Senators (21-28), 8-3 | Tiger Stadium (9-16) | 22-33 | Lost 4 |
| » Starters: Tom Zachary vs Earl Whitehill | Sixth | 21½ out |
| Friday, June 15 |
| » Lost to Senators (22-28), 5-4 | Tiger Stadium (9-17) | 22-34 | Lost 5 |
| » Starters: Garland Braxton vs Sam Gibson | Seventh | 21½ out |
| Saturday, June 16 |
| » Defeated Senators (22-29), 4-1 | Tiger Stadium (10-17) | 23-34 | |
| » Starters: Bump Hadley vs Ownie Carroll | Seventh | 20½ out |
| Sunday, June 17 |
| » Lost to Senators (23-29), 12-0 | Tiger Stadium (10-18) | 23-35 | |
| » Starters: Sam Jones vs Elam Vangilder | Seventh | 21½ out |
| Thursday, June 21 |
| » Lost to Browns (31-28), 8-3 | Sportsman's Park III (3-2) | 23-36 | Lost 2 |
| » Starters: Ownie Carroll vs Alvin Crowder | Seventh | 23 out |
| » Lost to Browns (32-28), 9-5 | Sportsman's Park III (3-3) | 23-37 | Lost 3 |
| » Starters: Earl Whitehill vs Dick Coffman | Seventh | 23 out |
| Friday, June 22 |
| » Lost to Browns (33-28), 8-3 | Sportsman's Park III (3-4) | 23-38 | Lost 4 |
| » Starters: Vic Sorrell vs Jack Ogden | Seventh | 23 out |
| » Defeated Browns (33-29), 12-6 | Sportsman's Park III (4-4) | 24-38 | |
| » Starters: Josh Billings vs Boom-Boom Beck | Seventh | 23 out |
| Saturday, June 23 |
| » Lost to White Sox (24-37), 6-4 | Tiger Stadium (10-19) | 24-39 | |
| » Starters: Red Faber vs Sam Gibson | Eighth | 22½ out |
| Sunday, June 24 |
| » Defeated White Sox (24-38), 6-0 | Tiger Stadium (11-19) | 25-39 | |
| » Starters: Ted Lyons vs Ownie Carroll | Seventh | 22½ out |
| Monday, June 25 |
| » Lost to White Sox (25-38), 8-6 | Tiger Stadium (11-20) | 25-40 | |
| » Starters: Tommy Thomas vs Earl Whitehill | Eighth | 23 out |
| Tuesday, June 26 |
| » Lost to White Sox (26-38), 5-2 | Tiger Stadium (11-21) | 25-41 | Lost 2 |
| » Starters: Grady Adkins vs Ken Holloway | Eighth | 23½ out |
| Thursday, June 28 |
| » Lost to Browns (36-31), 5-2 | Tiger Stadium (11-22) | 25-42 | Lost 3 |
| » Starters: Dolly Gray vs George Smith | Eighth | 25 out |
| Saturday, June 30 |
| » Defeated Browns (36-32), 11-3 | Tiger Stadium (12-22) | 26-42 | |
| » Starters: Jack Ogden vs Ownie Carroll | Eighth | 25½ out |
| » Lost to Browns (37-32), 5-4 | Tiger Stadium (12-23) | 26-43 | |
| » Starters: Alvin Crowder vs Josh Billings | Eighth | 25½ out |
| Sunday, July 1 |
| » Defeated Browns (37-33), 7-4 | Tiger Stadium (13-23) | 27-43 | |
| » Starters: Dick Coffman vs Vic Sorrell | Eighth | 26 out |
| Monday, July 2 |
| » Defeated Indians (33-39), 7-3 | Tiger Stadium (14-23) | 28-43 | Won 2 |
| » Starters: George Uhle vs Earl Whitehill | Eighth | 25 out |
| Tuesday, July 3 |
| » Lost to Indians (34-39), 6-5 | Tiger Stadium (14-24) | 28-44 | |
| » Starters: George Grant vs Ken Holloway | Eighth | 26 out |
| Wednesday, July 4 |
| » Defeated Indians (34-40), 10-5 | Tiger Stadium (15-24) | 29-44 | |
| » Starters: Joe Shaute vs Ownie Carroll | Eighth | 26 out |
| » Lost to Indians (35-40), 4-3 | Tiger Stadium (15-25) | 29-45 | |
| » Starters: Jake Miller vs Josh Billings | Eighth | 26 out |
| Saturday, July 7 |
| » Defeated Red Sox (30-42), 20-8 | Fenway Park (1-2) | 30-45 | |
| » Starters: Lil Stoner vs Slim Harriss | Eighth | 26 out |
| » Defeated Red Sox (30-43), 4-3 | Fenway Park (2-2) | 31-45 | Won 2 |
| » Starters: Vic Sorrell vs Danny MacFayden | Eighth | 26 out |
| Monday, July 9 |
| » Lost to Red Sox (31-43), 4-0 | Fenway Park (2-3) | 31-46 | |
| » Starters: Earl Whitehill vs Jack Russell | Eighth | 26 out |
| » Lost to Red Sox (32-43), 8-2 | Fenway Park (2-4) | 31-47 | Lost 2 |
| » Starters: Ownie Carroll vs Ed Morris | Eighth | 26 out |
| Wednesday, July 11 |
| » Defeated Yankees (57-22), 4-2 | Yankee Stadium (1-4) | 32-47 | |
| » Starters: Ken Holloway vs George Pipgras | Eighth | 26 out |
| » Lost to Yankees (58-22), 6-5 | Yankee Stadium (1-5) | 32-48 | |
| » Starters: Josh Billings vs Waite Hoyt | Eighth | 26 out |
| Thursday, July 12 |
| » Defeated Yankees (58-23), 4-2 | Yankee Stadium (2-5) | 33-48 | |
| » Starters: Lil Stoner vs Hank Johnson | Eighth | 25 out |
| Monday, July 16 |
| » Lost to Athletics (49-34), 3-2 | Shibe Park (0-4) | 33-49 | |
| » Starters: Vic Sorrell vs Jack Quinn | Seventh | 27 out |
| » Defeated Athletics (49-35), 11-6 | Shibe Park (1-4) | 34-49 | |
| » Starters: Earl Whitehill vs George Earnshaw | Seventh | 27 out |
| Tuesday, July 17 |
| » Lost to Athletics (50-35), 6-2 | Shibe Park (1-5) | 34-50 | |
| » Starters: Ken Holloway vs Lefty Grove | Eighth | 28 out |
| Wednesday, July 18 |
| » Lost to Athletics (51-35), 5-1 | Shibe Park (1-6) | 34-51 | Lost 2 |
| » Starters: Sam Gibson vs Howard Ehmke | Eighth | 29 out |
| Former Tiger Ed Killian dies in Detroit, MI at the age of 52. |
| Thursday, July 19 |
| » Defeated Senators (36-51), 9-3 | Griffith Stadium (3-1) | 35-51 | |
| » Starters: Ownie Carroll vs Tom Zachary | Eighth | 29½ out |
| » Lost to Senators (37-51), 7-2 | Griffith Stadium (3-2) | 35-52 | |
| » Starters: Lil Stoner vs Milt Gaston | Eighth | 29½ out |
| » Major-league debuts: Harley Boss (Senators) |
| Friday, July 20 |
| » Lost to Senators (38-51), 7-4 | Griffith Stadium (3-3) | 35-53 | Lost 2 |
| » Starters: Vic Sorrell vs Sam Jones | Eighth | 30 out |
| Saturday, July 21 |
| » Lost to Senators (39-51), 4-2 | Griffith Stadium (3-4) | 35-54 | Lost 3 |
| » Starters: Earl Whitehill vs Bump Hadley | Eighth | 31 out |
| Sunday, July 22 |
| » Lost to Senators (40-51), 8-2 | Griffith Stadium (3-5) | 35-55 | Lost 4 |
| » Starters: Ken Holloway vs Garland Braxton | Eighth | 31 out |
| Wednesday, July 25 |
| » Defeated Yankees (67-26), 3-2 | Tiger Stadium (16-25) | 36-55 | |
| » Starters: George Pipgras vs Lil Stoner | Eighth | 29 out |
| » Defeated Yankees (67-27), 10-7 | Tiger Stadium (17-25) | 37-55 | Won 2 |
| » Starters: Hank Johnson vs Ownie Carroll | Eighth | 29 out |
| Thursday, July 26 |
| » Lost to Yankees (68-27), 12-1 | Tiger Stadium (17-26) | 37-56 | |
| » Starters: Waite Hoyt vs Vic Sorrell | Seventh | 29 out |
| » Defeated Yankees (68-28), 13-10 | Tiger Stadium (18-26) | 38-56 | |
| » Starters: Wilcy Moore vs Earl Whitehill | Seventh | 29 out |
| Saturday, July 28 |
| » Defeated Red Sox (37-57), 7-1 | Tiger Stadium (19-26) | 39-56 | Won 2 |
| » Starters: Marty Griffin vs Ownie Carroll | Sixth | 28 out |
| » Defeated Red Sox (37-58), 8-7 | Tiger Stadium (20-26) | 40-56 | Won 3 |
| » Starters: Danny MacFayden vs George Smith | Sixth | 28 out |
| Sunday, July 29 |
| » Lost to Red Sox (38-58), 5-2 | Tiger Stadium (20-27) | 40-57 | |
| » Starters: Jack Russell vs Lil Stoner | Seventh | 28 out |
| Monday, July 30 |
| » Defeated Red Sox (38-59), 2-1 | Tiger Stadium (21-27) | 41-57 | |
| » Starters: Ed Morris vs Ken Holloway | Seventh | 27 out |
| Tuesday, July 31 |
| » Defeated Red Sox (38-60), 7-2 | Tiger Stadium (22-27) | 42-57 | Won 2 |
| » Starters: Red Ruffing vs Vic Sorrell | Seventh | 27 out |
| Wednesday, August 1 |
| » Defeated Senators (46-58), 10-5 | Tiger Stadium (23-27) | 43-57 | Won 3 |
| » Starters: Tom Zachary vs Earl Whitehill | Sixth | 27 out |
| Thursday, August 2 |
| » Defeated Senators (46-59), 5-4 | Tiger Stadium (24-27) | 44-57 | Won 4 |
| » Starters: Bump Hadley vs Ownie Carroll | Seventh | 26 out |
| Friday, August 3 |
| » Lost to Senators (47-59), 9-3 | Tiger Stadium (24-28) | 44-58 | |
| » Starters: Sam Jones vs Lil Stoner | Sixth | 26 out |
| Saturday, August 4 |
| » Lost to Athletics (67-37), 7-4 | Tiger Stadium (24-29) | 44-59 | Lost 2 |
| » Starters: Jack Quinn vs Ken Holloway | Seventh | 27 out |
| Sunday, August 5 |
| » Lost to Athletics (68-37), 5-1 | Tiger Stadium (24-30) | 44-60 | Lost 3 |
| » Starters: Lefty Grove vs Vic Sorrell | Seventh | 27 out |
| Monday, August 6 |
| » Defeated Athletics (68-38), 8-5 | Tiger Stadium (25-30) | 45-60 | |
| » Starters: George Earnshaw vs Earl Whitehill | Sixth | 26 out |
| Future Tiger Herb Moford is born in Brooksville, KY. |
| Tuesday, August 7 |
| » Defeated Athletics (68-39), 4-1 | Tiger Stadium (26-30) | 46-60 | Won 2 |
| » Starters: Rube Walberg vs Ownie Carroll | Sixth | 26 out |
| Friday, August 10 |
| » Defeated Indians (50-60), 8-7 | League Park II (6-3) | 47-60 | Won 3 |
| » Starters: Ken Holloway vs Willis Hudlin | Sixth | 26½ out |
| Saturday, August 11 |
| » Defeated Indians (50-61), 10-4 | League Park II (7-3) | 48-60 | Won 4 |
| » Starters: Vic Sorrell vs Joe Shaute | Sixth | 26½ out |
| Sunday, August 12 |
| » Lost to Indians (51-61), 3-2 | League Park II (7-4) | 48-61 | |
| » Starters: Earl Whitehill vs Jake Miller | Fifth | 27½ out |
| Monday, August 13 |
| » Lost to Athletics (72-39), 7-1 | Shibe Park (1-7) | 48-62 | Lost 2 |
| » Starters: Ownie Carroll vs Lefty Grove | Sixth | 28 out |
| Tuesday, August 14 |
| » Defeated Athletics (72-40), 4-1 | Shibe Park (2-7) | 49-62 | |
| » Starters: Elam Vangilder vs Howard Ehmke | Sixth | 27 out |
| Wednesday, August 15 |
| » Defeated Athletics (72-41), 6-3 | Shibe Park (3-7) | 50-62 | Won 2 |
| » Starters: Sam Gibson vs Jack Quinn | Sixth | 26 out |
| Thursday, August 16 |
| » Lost to Athletics (73-41), 18-6 | Shibe Park (3-8) | 50-63 | |
| » Starters: Vic Sorrell vs George Earnshaw | Sixth | 27 out |
| Friday, August 17 |
| » Lost to Senators (52-65), 3-1 | Griffith Stadium (3-6) | 50-64 | Lost 2 |
| » Starters: Earl Whitehill vs Bump Hadley | Seventh | 27½ out |
| Saturday, August 18 |
| » Lost to Senators (53-65), 3-1 | Griffith Stadium (3-7) | 50-65 | Lost 3 |
| » Starters: Ownie Carroll vs Firpo Marberry | Seventh | 28½ out |
| Sunday, August 19 |
| » Defeated Senators (53-66), 9-6 | Griffith Stadium (4-7) | 51-65 | |
| » Starters: Vic Sorrell vs Sam Jones | Seventh | 28 out |
| Future Tiger Jim Finigan is born in Quincy, IL. |
| Monday, August 20 |
| » Major-league debuts: Art Shires (White Sox) |
| Tuesday, August 21 |
| » Defeated Red Sox (43-75), 4-3 | Fenway Park (3-4) | 52-65 | Won 2 |
| » Starters: Elam Vangilder vs Slim Harriss | Sixth | 28 out |
| Wednesday, August 22 |
| » Defeated Red Sox (43-76), 7-6 | Fenway Park (4-4) | 53-65 | Won 3 |
| » Starters: Sam Gibson vs Danny MacFayden | Sixth | 27 out |
| » Defeated Red Sox (43-77), 4-3 | Fenway Park (5-4) | 54-65 | Won 4 |
| » Starters: Earl Whitehill vs Ed Morris | Sixth | 27 out |
| Thursday, August 23 |
| » Defeated Red Sox (43-78), 2-1 | Fenway Park (6-4) | 55-65 | Won 5 |
| » Starters: Ownie Carroll vs Jack Russell | Fourth | 26½ out |
| Friday, August 24 |
| » Lost to Red Sox (44-78), 2-1 | Fenway Park (6-5) | 55-66 | |
| » Starters: Lil Stoner vs Red Ruffing | Fourth | 26 out |
| Saturday, August 25 |
| » Defeated Yankees (81-41), 9-3 | Yankee Stadium (3-5) | 56-66 | |
| » Starters: Vic Sorrell vs Hank Johnson | Fourth | 26 out |
| » Lost to Yankees (82-41), 7-0 | Yankee Stadium (3-6) | 56-67 | |
| » Starters: Elam Vangilder vs Waite Hoyt | Fourth | 26 out |
| Monday, August 27 |
| » Lost to Yankees (83-41), 4-3 | Yankee Stadium (3-7) | 56-68 | Lost 2 |
| » Starters: Earl Whitehill vs Tom Zachary | Seventh | 28 out |
| » Lost to Yankees (84-41), 5-2 | Yankee Stadium (3-8) | 56-69 | Lost 3 |
| » Starters: Ownie Carroll vs George Pipgras | Seventh | 28 out |
| Tuesday, August 28 |
| » Defeated Indians (57-71), 8-4 | Tiger Stadium (27-30) | 57-69 | |
| » Starters: Jake Miller vs Sam Gibson | Fourth | 27½ out |
| Wednesday, August 29 |
| » Lost to Indians (58-71), 9-5 | Tiger Stadium (27-31) | 57-70 | |
| » Starters: Joe Shaute vs Lil Stoner | Sixth | 28 out |
| Thursday, August 30 |
| » Defeated Indians (58-72), 5-3 | Tiger Stadium (28-31) | 58-70 | |
| » Starters: Willis Hudlin vs Vic Sorrell | Fifth | 27 out |
| Friday, August 31 |
| » Lost to Browns (69-60), 5-2 | Sportsman's Park III (4-5) | 58-71 | |
| » Starters: Earl Whitehill vs Alvin Crowder | Fifth | 27½ out |
| » Major-league debuts: John Stone (Tigers) |
| Saturday, September 1 |
| » Defeated Browns (69-61), 6-4 | Sportsman's Park III (5-5) | 59-71 | |
| » Starters: Ownie Carroll vs Jack Ogden | Fourth | 27½ out |
| Sunday, September 2 |
| » Lost to Browns (70-61), 5-4 | Sportsman's Park III (5-6) | 59-72 | |
| » Starters: Elam Vangilder vs Dolly Gray | Fifth | 27½ out |
| Monday, September 3 |
| » Lost to White Sox (58-71), 5-2 | Comiskey Park I (3-4) | 59-73 | Lost 2 |
| » Starters: Vic Sorrell vs Grady Adkins | Sixth | 28½ out |
| » Lost to White Sox (59-71), 7-5 | Comiskey Park I (3-5) | 59-74 | Lost 3 |
| » Starters: Sam Gibson vs Ted Blankenship | Sixth | 28½ out |
| Tuesday, September 4 |
| » Lost to White Sox (60-71), 3-2 | Comiskey Park I (3-6) | 59-75 | Lost 4 |
| » Starters: Ownie Carroll vs Ted Lyons | Fifth | 29½ out |
| » Lost to White Sox (61-71), 3-2 | Comiskey Park I (3-7) | 59-76 | Lost 5 |
| » Starters: Ken Holloway vs Red Faber | Fifth | 29½ out |
| Wednesday, September 5 |
| » Defeated White Sox (61-72), 10-2 | Comiskey Park I (4-7) | 60-76 | |
| » Starters: Lil Stoner vs Ed Walsh | Sixth | 29 out |
| Saturday, September 8 |
| » Defeated Browns (73-62), 6-2 | Tiger Stadium (29-31) | 61-76 | Won 2 |
| » Starters: Dolly Gray vs Earl Whitehill | Sixth | 28½ out |
| Sunday, September 9 |
| » Lost to Browns (74-62), 8-6 | Tiger Stadium (29-32) | 61-77 | |
| » Starters: Alvin Crowder vs Vic Sorrell | Sixth | 29½ out |
| Monday, September 10 |
| » Lost to White Sox (65-72), 6-4 | Tiger Stadium (29-33) | 61-78 | Lost 2 |
| » Starters: Red Faber vs Sam Gibson | Sixth | 30 out |
| Tuesday, September 11 |
| » Defeated White Sox (65-73), 7-6 | Tiger Stadium (30-33) | 62-78 | |
| » Starters: Tommy Thomas vs Ownie Carroll | Sixth | 30 out |
| Saturday, September 15 |
| » Lost to Senators (66-75), 12-2 | Tiger Stadium (30-34) | 62-79 | |
| » Starters: Garland Braxton vs Earl Whitehill | Sixth | 29½ out |
| Sunday, September 16 |
| » Lost to Senators (67-75), 11-7 | Tiger Stadium (30-35) | 62-80 | Lost 2 |
| » Starters: Sam Jones vs Vic Sorrell | Sixth | 30½ out |
| Future Tiger Vito Valentinetti is born in West New York, NJ. |
| Monday, September 17 |
| » Lost to Senators (68-75), 4-3 | Tiger Stadium (30-36) | 62-81 | Lost 3 |
| » Starters: Firpo Marberry vs Ownie Carroll | Sixth | 31½ out |
| Tuesday, September 18 |
| » Defeated Senators (68-76), 8-5 | Tiger Stadium (31-36) | 63-81 | |
| » Starters: Bump Hadley vs Phil Page | Fifth | 31½ out |
| Thursday, September 20 |
| » Lost to Athletics (93-51), 6-1 | Tiger Stadium (31-37) | 63-82 | |
| » Starters: Jack Quinn vs Earl Whitehill | Sixth | 31½ out |
| Friday, September 21 |
| » Defeated Athletics (93-52), 9-4 | Tiger Stadium (32-37) | 64-82 | |
| » Starters: Lefty Grove vs Elam Vangilder | Sixth | 31½ out |
| Saturday, September 22 |
| » Defeated Athletics (93-53), 5-4 | Tiger Stadium (33-37) | 65-82 | Won 2 |
| » Starters: Rube Walberg vs Vic Sorrell | Sixth | 30½ out |
| Sunday, September 23 |
| » Defeated Red Sox (53-94), 4-1 | Tiger Stadium (34-37) | 66-82 | Won 3 |
| » Starters: Jack Russell vs Phil Page | Fifth | 30½ out |
| Monday, September 24 |
| » Defeated Red Sox (53-95), 8-0 | Tiger Stadium (35-37) | 67-82 | Won 4 |
| » Starters: Pat Simmons vs Sam Gibson | Sixth | 29½ out |
| Thursday, September 27 |
| » Lost to Yankees (98-52), 4-3 | Tiger Stadium (35-38) | 67-83 | |
| » Starters: Waite Hoyt vs Ownie Carroll | Sixth | 32 out |
| » Lost to Yankees (99-52), 8-5 | Tiger Stadium (35-39) | 67-84 | Lost 2 |
| » Starters: Fred Heimach vs Vic Sorrell | Sixth | 32 out |
| Friday, September 28 |
| » Lost to Yankees (100-52), 11-6 | Tiger Stadium (35-40) | 67-85 | Lost 3 |
| » Starters: George Pipgras vs Sam Gibson | Sixth | 33 out |
| Future Tiger Dick Gernert is born in Reading, PA. |
| Saturday, September 29 |
| » Defeated Yankees (100-53), 19-10 | Tiger Stadium (36-40) | 68-85 | |
| » Starters: Tom Zachary vs Elam Vangilder | Sixth | 32 out |
| Sunday, September 30 |
| » Lost to Yankees (101-53), 7-6 | Tiger Stadium (36-41) | 68-86 | |
| » Starters: Waite Hoyt vs Vic Sorrell | Sixth | 33 out |
| Sunday, October 7 |
| Future Tiger Joe Presko is born in Kansas City, MO. |
| Wednesday, October 24 |
| Future Tiger George Bullard is born in Lynn, MA. |
| Tuesday, November 13 |
| Future Tiger Steve Bilko is born in Nanticoke, PA. |
| Sunday, November 25 |
| Future Tiger Ray Narleski is born in Camden, NJ. |
Game information provided by Retrosheet (www.retrosheet.org) |