| Saturday, January 8 |
| Future Indian Jim Busby is born in Kenedy, TX. |
| Wednesday, January 26 |
| Future Indian Bob Nieman is born in Cincinnati, OH. |
| Monday, March 21 |
| Future Indian Owen Friend is born in Granite City, IL. |
| Sunday, March 27 |
| Future Indian Dick Rozek is born in Cedar Rapids, IA. |
| Tuesday, April 12 |
| » Defeated White Sox (0-1), 3-2 | League Park II (1-0) | 1-0 | |
| » Starters: Tommy Thomas vs George Uhle | First | -- |
| » Major-league debuts: Randy Moore (White Sox) |
| Wednesday, April 13 |
| » Lost to White Sox (1-1), 7-2 | League Park II (1-1) | 1-1 | |
| » Starters: Ted Blankenship vs Dutch Levsen | Fourth | 1 out |
| Thursday, April 14 |
| » Defeated White Sox (1-2), 3-2 | League Park II (2-1) | 2-1 | |
| » Starters: Charlie Barnabe vs Benn Karr | Second | ½ out |
| Friday, April 15 |
| » Lost to White Sox (2-2), 6-1 | League Park II (2-2) | 2-2 | |
| » Starters: Ted Lyons vs Joe Shaute | Third | 1½ out |
| Sunday, April 17 |
| » Lost to Tigers (1-0), 5-1 | League Park II (2-3) | 2-3 | Lost 2 |
| » Starters: Sam Gibson vs George Uhle | Sixth | 3 out |
| Monday, April 18 |
| » Defeated Tigers (1-1), 3-2 | League Park II (3-3) | 3-3 | |
| » Starters: Ken Holloway vs Dutch Levsen | Fifth | 3 out |
| Tuesday, April 19 |
| » Lost to Tigers (2-1), 8-5 | League Park II (3-4) | 3-4 | |
| » Starters: Lil Stoner vs Benn Karr | Fifth | 3 out |
| Wednesday, April 20 |
| » Defeated White Sox (3-6), 5-4 | Comiskey Park I (1-0) | 4-4 | |
| » Starters: Joe Shaute vs Ted Lyons | Fifth | 2 out |
| Saturday, April 23 |
| » Lost to White Sox (4-6), 8-2 | Comiskey Park I (1-1) | 4-5 | |
| » Starters: George Uhle vs Tommy Thomas | Sixth | 2½ out |
| Sunday, April 24 |
| » Lost to Browns (5-2), 9-4 | League Park II (3-5) | 4-6 | Lost 2 |
| » Starters: Tom Zachary vs Dutch Levsen | Sixth | 3½ out |
| Monday, April 25 |
| » Defeated Browns (5-3), 9-1 | League Park II (4-5) | 5-6 | |
| » Starters: Win Ballou vs Benn Karr | Sixth | 2½ out |
| Tuesday, April 26 |
| » Defeated Browns (5-4), 6-2 | League Park II (5-5) | 6-6 | Won 2 |
| » Starters: Milt Gaston vs Willis Hudlin | Sixth | 2 out |
| Future Indian Granny Hamner is born in Richmond, VA. |
| Wednesday, April 27 |
| » Lost to Browns (6-4), 4-2 | League Park II (5-6) | 6-7 | |
| » Starters: Sam Jones vs Sherry Smith | Fifth | 2½ out |
| Thursday, April 28 |
| » Lost to Tigers (5-5), 6-5 | Tiger Stadium (0-1) | 6-8 | Lost 2 |
| » Starters: George Uhle vs Ken Holloway | Seventh | 3 out |
| Friday, April 29 |
| » Lost to Tigers (6-5), 5-2 | Tiger Stadium (0-2) | 6-9 | Lost 3 |
| » Starters: Garland Buckeye vs Rip Collins | Sixth | 4 out |
| Saturday, April 30 |
| » Defeated Tigers (6-6), 6-2 | Tiger Stadium (1-2) | 7-9 | |
| » Starters: Willis Hudlin vs Ed Wells | Fifth | 3 out |
| » Major-league debuts: Jim Walkup (Tigers) |
| Sunday, May 1 |
| » Lost to Tigers (7-6), 7-0 | Tiger Stadium (1-3) | 7-10 | |
| » Starters: Benn Karr vs Earl Whitehill | Seventh | 4 out |
| Monday, May 2 |
| » Lost to Browns (7-7), 7-6 | Sportsman's Park III (0-1) | 7-11 | Lost 2 |
| » Starters: George Uhle vs Tom Zachary | Sixth | 5 out |
| Tuesday, May 3 |
| » Defeated Browns (7-8), 5-3 | Sportsman's Park III (1-1) | 8-11 | |
| » Starters: Garland Buckeye vs Win Ballou | Seventh | 5 out |
| Wednesday, May 4 |
| » Lost to Browns (8-8), 13-3 | Sportsman's Park III (1-2) | 8-12 | |
| » Starters: Dutch Levsen vs Milt Gaston | Sixth | 5 out |
| Saturday, May 7 |
| » Defeated Athletics (11-8), 11-10 | League Park II (6-6) | 9-12 | |
| » Starters: Rube Walberg vs Willis Hudlin | Seventh | 4½ out |
| » Major-league debuts: Johnny Burnett (Indians) |
| Sunday, May 8 |
| » Defeated Athletics (11-9), 4-2 | League Park II (7-6) | 10-12 | Won 2 |
| » Starters: Howard Ehmke vs Garland Buckeye | Seventh | 4½ out |
| Monday, May 9 |
| » Defeated Athletics (11-10), 6-1 | League Park II (8-6) | 11-12 | Won 3 |
| » Starters: Rube Walberg vs Joe Shaute | Sixth | 3½ out |
| Tuesday, May 10 |
| » Lost to Red Sox (6-16), 6-5 | League Park II (8-7) | 11-13 | |
| » Starters: Hal Wiltse vs Benn Karr | Seventh | 4½ out |
| Friday, May 13 |
| » Lost to Red Sox (7-16), 7-0 | League Park II (8-8) | 11-14 | Lost 2 |
| » Starters: Del Lundgren vs Garland Buckeye | Sixth | 6½ out |
| Saturday, May 14 |
| » Defeated Senators (11-14), 5-2 | League Park II (9-8) | 12-14 | |
| » Starters: Sloppy Thurston vs George Uhle | Fifth | 6 out |
| Tuesday, May 17 |
| » Lost to Senators (12-14), 12-0 | League Park II (9-9) | 12-15 | |
| » Starters: Hod Lisenbee vs Joe Shaute | Fifth | 7½ out |
| Thursday, May 19 |
| » Lost to Yankees (21-8), 4-3 | League Park II (9-10) | 12-16 | Lost 2 |
| » Starters: Urban Shocker vs Garland Buckeye | Sixth | 8½ out |
| Friday, May 20 |
| » Defeated Yankees (21-9), 2-1 | League Park II (10-10) | 13-16 | |
| » Starters: Waite Hoyt vs George Uhle | Sixth | 7½ out |
| Saturday, May 21 |
| » Defeated Yankees (21-10), 5-4 | League Park II (11-10) | 14-16 | Won 2 |
| » Starters: Dutch Ruether vs Dutch Levsen | Sixth | 6½ out |
| Sunday, May 22 |
| » Lost to Yankees (22-10), 7-2 | League Park II (11-11) | 14-17 | |
| » Starters: Urban Shocker vs Joe Shaute | Sixth | 7½ out |
| Monday, May 23 |
| » Defeated Tigers (13-17), 9-4 | League Park II (12-11) | 15-17 | |
| » Starters: Rip Collins vs Garland Buckeye | Sixth | 7 out |
| » Lost to Tigers (14-17), 7-5 | League Park II (12-12) | 15-18 | |
| » Starters: Ownie Carroll vs Dutch Levsen | Sixth | 7 out |
| Tuesday, May 24 |
| » Lost to Tigers (15-17), 6-3 | League Park II (12-13) | 15-19 | Lost 2 |
| » Starters: Lil Stoner vs George Uhle | Seventh | 7½ out |
| Wednesday, May 25 |
| » Defeated Tigers (15-18), 9-6 | League Park II (13-13) | 16-19 | |
| » Starters: Don Hankins vs Willis Hudlin | Sixth | 7 out |
| Thursday, May 26 |
| » Lost to Browns (17-17), 2-1 | Sportsman's Park III (1-3) | 16-20 | |
| » Starters: Jake Miller vs Lefty Stewart | Sixth | 7 out |
| » Defeated Browns (17-18), 9-7 | Sportsman's Park III (2-3) | 17-20 | |
| » Starters: George Uhle vs Ernie Wingard | Sixth | 7 out |
| Friday, May 27 |
| » Defeated Browns (17-19), 7-3 | Sportsman's Park III (3-3) | 18-20 | Won 2 |
| » Starters: Garland Buckeye vs Sam Jones | Fifth | 6½ out |
| Sunday, May 29 |
| » Lost to Browns (18-19), 7-4 | Sportsman's Park III (3-4) | 18-21 | |
| » Starters: Willis Hudlin vs Milt Gaston | Fifth | 7 out |
| » Defeated Browns (18-20), 10-2 | Sportsman's Park III (4-4) | 19-21 | |
| » Starters: Dutch Levsen vs Elam Vangilder | Fifth | 7 out |
| Monday, May 30 |
| » Defeated Tigers (16-22), 9-8 | Tiger Stadium (2-3) | 20-21 | Won 2 |
| » Starters: Jake Miller vs Ownie Carroll | Fifth | 7 out |
| » Lost to Tigers (17-22), 11-3 | Tiger Stadium (2-4) | 20-22 | |
| » Starters: George Uhle vs Ken Holloway | Fifth | 7 out |
| Tuesday, May 31 |
| » Lost to Tigers (18-22), 1-0 | Tiger Stadium (2-5) | 20-23 | Lost 2 |
| » Starters: Garland Buckeye vs Rip Collins | Fifth | 8½ out |
| Wednesday, June 1 |
| » Defeated Tigers (18-23), 14-1 | Tiger Stadium (3-5) | 21-23 | |
| » Starters: Willis Hudlin vs Sam Gibson | Fifth | 8½ out |
| Thursday, June 2 |
| » Lost to Athletics (23-21), 8-4 | Shibe Park (0-1) | 21-24 | |
| » Starters: Joe Shaute vs Dolly Gray | Fifth | 9½ out |
| Friday, June 3 |
| » Defeated Athletics (23-22), 3-1 | Shibe Park (1-1) | 22-24 | |
| » Starters: Jake Miller vs Jack Quinn | Fifth | 8½ out |
| Monday, June 6 |
| » Lost to Athletics (24-22), 4-1 | Shibe Park (1-2) | 22-25 | |
| » Starters: Garland Buckeye vs Howard Ehmke | Fifth | 9½ out |
| Tuesday, June 7 |
| » Lost to Senators (21-23), 10-8 | Griffith Stadium (0-1) | 22-26 | Lost 2 |
| » Starters: Sherry Smith vs Sloppy Thurston | Sixth | 10½ out |
| Wednesday, June 8 |
| » Lost to Senators (22-23), 2-1 | Griffith Stadium (0-2) | 22-27 | Lost 3 |
| » Starters: Willis Hudlin vs Hod Lisenbee | Sixth | 11½ out |
| Thursday, June 9 |
| » Defeated Senators (22-24), 7-1 | Griffith Stadium (1-2) | 23-27 | |
| » Starters: George Uhle vs Walter Johnson | Fifth | 11½ out |
| Friday, June 10 |
| » Lost to Senators (23-24), 6-5 | Griffith Stadium (1-3) | 23-28 | |
| » Starters: Jake Miller vs Bump Hadley | Sixth | 11½ out |
| Saturday, June 11 |
| » Lost to Yankees (35-16), 6-4 | Yankee Stadium (0-1) | 23-29 | Lost 2 |
| » Starters: Garland Buckeye vs Myles Thomas | Seventh | 12½ out |
| Sunday, June 12 |
| » Defeated Yankees (35-17), 8-7 | Yankee Stadium (1-1) | 24-29 | |
| » Starters: Willis Hudlin vs Waite Hoyt | Seventh | 11½ out |
| Monday, June 13 |
| » Lost to Yankees (36-17), 14-6 | Yankee Stadium (1-2) | 24-30 | |
| » Starters: Joe Shaute vs Herb Pennock | Sixth | 12½ out |
| Thursday, June 16 |
| » Lost to Red Sox (14-37), 11-10 | Fenway Park (0-1) | 24-31 | Lost 2 |
| » Starters: George Uhle vs Tony Welzer | Seventh | 13½ out |
| Friday, June 17 |
| » Defeated Red Sox (14-38), 6-3 | Fenway Park (1-1) | 25-31 | |
| » Starters: Willis Hudlin vs Hal Wiltse | Sixth | 13 out |
| » Defeated Red Sox (14-39), 4-3 | Fenway Park (2-1) | 26-31 | Won 2 |
| » Starters: Jake Miller vs Red Ruffing | Sixth | 13 out |
| Saturday, June 18 |
| » Lost to Red Sox (15-39), 5-0 | Fenway Park (2-2) | 26-32 | |
| » Starters: Garland Buckeye vs Del Lundgren | Sixth | 14 out |
| Sunday, June 19 |
| » Defeated White Sox (34-26), 3-2 | League Park II (14-13) | 27-32 | |
| » Starters: Ted Lyons vs Joe Shaute | Sixth | 13½ out |
| Tuesday, June 21 |
| Future Indian Jackie Collum is born in Victor, IA. |
| Thursday, June 23 |
| » Defeated Browns (25-32), 7-2 | League Park II (15-13) | 28-32 | Won 2 |
| » Starters: Elam Vangilder vs Willis Hudlin | Sixth | 15½ out |
| Friday, June 24 |
| » Lost to Browns (26-32), 2-1 | League Park II (15-14) | 28-33 | |
| » Starters: Ernie Wingard vs Joe Shaute | Sixth | 16 out |
| Sunday, June 26 |
| » Defeated Browns (26-33), 2-0 | League Park II (16-14) | 29-33 | |
| » Starters: Lefty Stewart vs George Uhle | Sixth | 15 out |
| » Lost to Browns (27-33), 7-3 | League Park II (16-15) | 29-34 | |
| » Starters: Milt Gaston vs Garland Buckeye | Sixth | 15 out |
| Monday, June 27 |
| » Lost to White Sox (37-30), 7-2 | Comiskey Park I (1-2) | 29-35 | Lost 2 |
| » Starters: Willis Hudlin vs Ted Lyons | Sixth | 15½ out |
| » Defeated White Sox (37-31), 12-4 | Comiskey Park I (2-2) | 30-35 | |
| » Starters: George Grant vs Bert Cole | Sixth | 15½ out |
| Tuesday, June 28 |
| » Lost to White Sox (38-31), 8-7 | Comiskey Park I (2-3) | 30-36 | |
| » Starters: Joe Shaute vs Sarge Connally | Sixth | 16½ out |
| Wednesday, June 29 |
| » Lost to White Sox (39-31), 5-0 | Comiskey Park I (2-4) | 30-37 | Lost 2 |
| » Starters: Dutch Levsen vs Ted Blankenship | Sixth | 17 out |
| » Defeated White Sox (39-32), 8-6 | Comiskey Park I (3-4) | 31-37 | |
| » Starters: Jake Miller vs Red Faber | Sixth | 17 out |
| Thursday, June 30 |
| » Lost to Tigers (34-30), 6-5 | League Park II (16-16) | 31-38 | |
| » Starters: Ken Holloway vs George Uhle | Sixth | 18 out |
| Friday, July 1 |
| » Lost to Tigers (35-30), 10-5 | League Park II (16-17) | 31-39 | Lost 2 |
| » Starters: Earl Whitehill vs George Grant | Sixth | 19 out |
| Saturday, July 2 |
| » Lost to Tigers (36-30), 6-1 | League Park II (16-18) | 31-40 | Lost 3 |
| » Starters: Sam Gibson vs Willis Hudlin | Sixth | 20 out |
| Sunday, July 3 |
| » Defeated Tigers (36-31), 10-9 | Tiger Stadium (4-5) | 32-40 | |
| » Starters: Garland Buckeye vs Rip Collins | Sixth | 19 out |
| Monday, July 4 |
| » Defeated White Sox (42-34), 2-0 | League Park II (17-18) | 33-40 | Won 2 |
| » Starters: Tommy Thomas vs Dutch Levsen | Sixth | 19 out |
| » Defeated White Sox (42-35), 6-2 | League Park II (18-18) | 34-40 | Won 3 |
| » Starters: Sarge Connally vs Joe Shaute | Sixth | 19 out |
| Friday, July 8 |
| » Lost to Senators (41-32), 7-4 | League Park II (18-19) | 34-41 | |
| » Starters: Bump Hadley vs George Uhle | Sixth | 20½ out |
| » Lost to Senators (42-32), 4-3 | League Park II (18-20) | 34-42 | Lost 2 |
| » Starters: Sloppy Thurston vs Joe Shaute | Sixth | 20½ out |
| Saturday, July 9 |
| » Lost to Senators (43-32), 6-5 | League Park II (18-21) | 34-43 | Lost 3 |
| » Starters: Bobby Burke vs Willis Hudlin | Sixth | 21½ out |
| » Lost to Senators (44-32), 3-2 | League Park II (18-22) | 34-44 | Lost 4 |
| » Starters: Walter Johnson vs Jake Miller | Sixth | 21½ out |
| Sunday, July 10 |
| » Lost to Senators (45-32), 10-9 | League Park II (18-23) | 34-45 | Lost 5 |
| » Starters: Hod Lisenbee vs Dutch Levsen | Sixth | 21½ out |
| Monday, July 11 |
| » Lost to Senators (46-32), 3-2 | League Park II (18-24) | 34-46 | Lost 6 |
| » Starters: Bump Hadley vs Garland Buckeye | Sixth | 22½ out |
| Tuesday, July 12 |
| » Lost to Yankees (58-24), 7-0 | League Park II (18-25) | 34-47 | Lost 7 |
| » Starters: Urban Shocker vs Joe Shaute | Sixth | 23½ out |
| Future Indian Jack Harshman is born in San Diego, CA. |
| Wednesday, July 13 |
| » Lost to Yankees (59-24), 5-3 | League Park II (18-26) | 34-48 | Lost 8 |
| » Starters: Dutch Ruether vs Willis Hudlin | Seventh | 24½ out |
| Future Indian Ruben Gomez is born in Arroyo, P.R. |
| Thursday, July 14 |
| » Defeated Yankees (59-25), 4-1 | League Park II (19-26) | 35-48 | |
| » Starters: Wilcy Moore vs Jake Miller | Seventh | 23½ out |
| Friday, July 15 |
| » Lost to Yankees (60-25), 10-9 | League Park II (19-27) | 35-49 | |
| » Starters: Waite Hoyt vs George Uhle | Seventh | 24½ out |
| Saturday, July 16 |
| » Lost to Red Sox (20-63), 6-3 | League Park II (19-28) | 35-50 | Lost 2 |
| » Starters: Del Lundgren vs Joe Shaute | Seventh | 26 out |
| » Lost to Red Sox (21-63), 5-4 | League Park II (19-29) | 35-51 | Lost 3 |
| » Starters: Danny MacFayden vs Dutch Levsen | Seventh | 26 out |
| Monday, July 18 |
| » Lost to Red Sox (22-63), 14-5 | League Park II (19-30) | 35-52 | Lost 4 |
| » Starters: Jack Russell vs Willis Hudlin | Seventh | 27 out |
| » Defeated Red Sox (22-64), 4-0 | League Park II (20-30) | 36-52 | |
| » Starters: Red Ruffing vs Garland Buckeye | Seventh | 27 out |
| Tuesday, July 19 |
| » Defeated Red Sox (22-65), 4-2 | League Park II (21-30) | 37-52 | Won 2 |
| » Starters: Hal Wiltse vs Jake Miller | Seventh | 27½ out |
| » Lost to Red Sox (23-65), 6-5 | League Park II (21-31) | 37-53 | |
| » Starters: Slim Harriss vs Dutch Levsen | Seventh | 27½ out |
| Thursday, July 21 |
| » Lost to Athletics (48-41), 8-3 | League Park II (21-32) | 37-54 | Lost 2 |
| » Starters: Jack Quinn vs Joe Shaute | Seventh | 28½ out |
| Sunday, July 24 |
| » Defeated Athletics (48-42), 9-6 | League Park II (22-32) | 38-54 | |
| » Starters: Eddie Rommel vs Garland Buckeye | Seventh | 28 out |
| » Defeated Athletics (48-43), 5-2 | League Park II (23-32) | 39-54 | Won 2 |
| » Starters: Rube Walberg vs Jake Miller | Seventh | 28 out |
| Future Indian Preston Ward is born in Columbia, MO. |
| Monday, July 25 |
| » Lost to Red Sox (25-67), 10-7 | Fenway Park (2-3) | 39-55 | |
| » Starters: George Uhle vs Del Lundgren | Seventh | 28½ out |
| Tuesday, July 26 |
| » Defeated Red Sox (25-68), 7-2 | Fenway Park (3-3) | 40-55 | |
| » Starters: Joe Shaute vs Red Ruffing | Sixth | 29 out |
| Thursday, July 28 |
| » Lost to Red Sox (26-68), 3-0 | Fenway Park (3-4) | 40-56 | |
| » Starters: Garland Buckeye vs Danny MacFayden | Sixth | 31 out |
| » Lost to Red Sox (27-68), 4-3 | Fenway Park (3-5) | 40-57 | Lost 2 |
| » Starters: Jake Miller vs Slim Harriss | Sixth | 31 out |
| Friday, July 29 |
| » Defeated Yankees (71-27), 6-4 | Yankee Stadium (2-2) | 41-57 | |
| » Starters: Willis Hudlin vs George Pipgras | Sixth | 30 out |
| Saturday, July 30 |
| » Lost to Yankees (72-27), 7-3 | Yankee Stadium (2-3) | 41-58 | |
| » Starters: George Uhle vs Dutch Ruether | Sixth | 32 out |
| » Lost to Yankees (73-27), 5-0 | Yankee Stadium (2-4) | 41-59 | Lost 2 |
| » Starters: Joe Shaute vs Waite Hoyt | Sixth | 32 out |
| Sunday, July 31 |
| Future Indian Al Aber is born in Cleveland, OH. |
| Monday, August 1 |
| » Defeated Yankees (73-28), 2-1 | Yankee Stadium (3-4) | 42-59 | |
| » Starters: Jake Miller vs Herb Pennock | Sixth | 31 out |
| Wednesday, August 3 |
| » Lost to Athletics (53-48), 9-2 | Shibe Park (1-3) | 42-60 | |
| » Starters: Joe Shaute vs Eddie Rommel | Sixth | 32 out |
| » Lost to Athletics (54-48), 7-4 | Shibe Park (1-4) | 42-61 | Lost 2 |
| » Starters: Willis Hudlin vs Rube Walberg | Sixth | 32 out |
| Thursday, August 4 |
| » Defeated Athletics (54-49), 3-0 | Shibe Park (2-4) | 43-61 | |
| » Starters: Garland Buckeye vs Lefty Grove | Sixth | 31 out |
| Saturday, August 6 |
| » Defeated Senators (62-41), 3-1 | Griffith Stadium (2-3) | 44-61 | Won 2 |
| » Starters: Jake Miller vs Hod Lisenbee | Sixth | 30½ out |
| Sunday, August 7 |
| » Lost to Senators (63-41), 12-3 | Griffith Stadium (2-4) | 44-62 | |
| » Starters: Willis Hudlin vs Bump Hadley | Sixth | 31½ out |
| Future Indian Rocky Bridges is born in Refugio, TX. Future Indian Art Houtteman is born in Detroit, MI. |
| Monday, August 8 |
| » Defeated Senators (63-42), 6-1 | Griffith Stadium (3-4) | 45-62 | |
| » Starters: Joe Shaute vs Walter Johnson | Sixth | 31 out |
| Future Indian Johnny Temple is born in Lexington, NC. |
| Tuesday, August 9 |
| » Lost to Senators (64-42), 4-2 | Griffith Stadium (3-5) | 45-63 | |
| » Starters: Garland Buckeye vs Sloppy Thurston | Sixth | 31 out |
| Wednesday, August 10 |
| Future Indian Bob Chakales is born. |
| Thursday, August 11 |
| » Defeated White Sox (52-57), 2-1 | League Park II (24-32) | 46-63 | |
| » Starters: Tommy Thomas vs Jake Miller | Sixth | 30½ out |
| Saturday, August 13 |
| » Defeated White Sox (52-58), 1-0 | League Park II (25-32) | 47-63 | Won 2 |
| » Starters: Ted Lyons vs Willis Hudlin | Sixth | 30½ out |
| Sunday, August 14 |
| » Lost to White Sox (53-58), 7-3 | League Park II (25-33) | 47-64 | |
| » Starters: Ted Blankenship vs Joe Shaute | Sixth | 31½ out |
| Tuesday, August 16 |
| » Lost to Athletics (61-51), 6-3 | League Park II (25-34) | 47-65 | Lost 2 |
| » Starters: Howard Ehmke vs Jake Miller | Sixth | 33 out |
| » Lost to Athletics (62-51), 8-0 | League Park II (25-35) | 47-66 | Lost 3 |
| » Starters: Jack Quinn vs Garland Buckeye | Sixth | 33 out |
| Wednesday, August 17 |
| » Lost to Athletics (63-51), 4-1 | League Park II (25-36) | 47-67 | Lost 4 |
| » Starters: Lefty Grove vs Willis Hudlin | Sixth | 34 out |
| Thursday, August 18 |
| » Defeated Athletics (63-52), 2-1 | League Park II (26-36) | 48-67 | |
| » Starters: Eddie Rommel vs Joe Shaute | Sixth | 34 out |
| Friday, August 19 |
| » Lost to Athletics (64-52), 5-3 | League Park II (26-37) | 48-68 | |
| » Starters: Rube Walberg vs Dutch Levsen | Sixth | 34 out |
| Saturday, August 20 |
| » Defeated Yankees (82-35), 14-8 | League Park II (27-37) | 49-68 | |
| » Starters: Dutch Ruether vs Jake Miller | Sixth | 33 out |
| Sunday, August 21 |
| » Defeated Yankees (82-36), 7-4 | League Park II (28-37) | 50-68 | Won 2 |
| » Starters: George Pipgras vs Garland Buckeye | Sixth | 32 out |
| Monday, August 22 |
| » Defeated Yankees (82-37), 9-4 | League Park II (29-37) | 51-68 | Won 3 |
| » Starters: Wilcy Moore vs Joe Shaute | Sixth | 31 out |
| Wednesday, August 24 |
| » Defeated Senators (66-53), 7-1 | League Park II (30-37) | 52-68 | Won 4 |
| » Starters: Sloppy Thurston vs Jake Miller | Sixth | 31 out |
| Thursday, August 25 |
| » Defeated Senators (66-54), 7-5 | League Park II (31-37) | 53-68 | Won 5 |
| » Starters: Tom Zachary vs Willis Hudlin | Sixth | 31 out |
| Friday, August 26 |
| » Defeated Senators (66-55), 8-7 | League Park II (32-37) | 54-68 | Won 6 |
| » Starters: Hod Lisenbee vs Joe Shaute | Sixth | 31 out |
| Saturday, August 27 |
| » Defeated Red Sox (37-84), 9-2 | League Park II (33-37) | 55-68 | Won 7 |
| » Starters: Hal Wiltse vs Willis Hudlin | Sixth | 31 out |
| Sunday, August 28 |
| » Lost to Red Sox (38-84), 6-5 | League Park II (33-38) | 55-69 | |
| » Starters: Danny MacFayden vs Jake Miller | Sixth | 32 out |
| Monday, August 29 |
| » Lost to Red Sox (39-84), 10-2 | League Park II (33-39) | 55-70 | Lost 2 |
| » Starters: Slim Harriss vs Garland Buckeye | Sixth | 33 out |
| Thursday, September 1 |
| » Defeated White Sox (59-65), 8-5 | Comiskey Park I (4-4) | 56-70 | |
| » Starters: Willis Hudlin vs Tommy Thomas | Sixth | 33 out |
| » Major-league debuts: Carl Reynolds (White Sox) |
| Friday, September 2 |
| » Defeated White Sox (59-66), 7-6 | Comiskey Park I (5-4) | 57-70 | Won 2 |
| » Starters: Jake Miller vs Ted Blankenship | Sixth | 33 out |
| Saturday, September 3 |
| » Lost to White Sox (60-66), 4-1 | Comiskey Park I (5-5) | 57-71 | |
| » Starters: Joe Shaute vs Red Faber | Sixth | 33 out |
| Sunday, September 4 |
| » Defeated White Sox (60-67), 6-3 | Comiskey Park I (6-5) | 58-71 | |
| » Starters: George Uhle vs Sarge Connally | Sixth | 32½ out |
| Monday, September 5 |
| » Defeated Browns (52-77), 7-6 | League Park II (34-39) | 59-71 | Won 2 |
| » Starters: Ernie Wingard vs Willis Hudlin | Sixth | 32½ out |
| » Lost to Browns (53-77), 3-2 | League Park II (34-40) | 59-72 | |
| » Starters: Win Ballou vs Garland Buckeye | Sixth | 32½ out |
| Tuesday, September 6 |
| » Lost to Browns (54-77), 7-4 | League Park II (34-41) | 59-73 | Lost 2 |
| » Starters: Milt Gaston vs Jake Miller | Sixth | 33 out |
| Thursday, September 8 |
| » Lost to Red Sox (43-89), 10-8 | Fenway Park (3-6) | 59-74 | Lost 3 |
| » Starters: Joe Shaute vs Del Lundgren | Sixth | 34½ out |
| Friday, September 9 |
| » Lost to Red Sox (44-89), 6-1 | Fenway Park (3-7) | 59-75 | Lost 4 |
| » Starters: Willis Hudlin vs Slim Harriss | Sixth | 35½ out |
| » Major-league debuts: Wes Ferrell (Indians) |
| Saturday, September 10 |
| » Defeated Red Sox (44-90), 3-1 | Fenway Park (4-7) | 60-75 | |
| » Starters: George Uhle vs Del Lundgren | Sixth | 35½ out |
| Tuesday, September 13 |
| » Lost to Yankees (97-41), 5-3 | Yankee Stadium (3-5) | 60-76 | |
| » Starters: Willis Hudlin vs George Pipgras | Sixth | 37 out |
| » Lost to Yankees (98-41), 5-3 | Yankee Stadium (3-6) | 60-77 | Lost 2 |
| » Starters: Joe Shaute vs Waite Hoyt | Sixth | 37 out |
| Wednesday, September 14 |
| » Lost to Yankees (99-41), 4-1 | Yankee Stadium (3-7) | 60-78 | Lost 3 |
| » Starters: Jake Miller vs Dutch Ruether | Sixth | 38 out |
| » Major-league debuts: Carl Lind (Indians) |
| Thursday, September 15 |
| » Defeated Yankees (99-42), 3-2 | Yankee Stadium (4-7) | 61-78 | |
| » Starters: George Uhle vs Myles Thomas | Sixth | 37 out |
| Saturday, September 17 |
| » Lost to Senators (75-65), 3-0 | Griffith Stadium (3-6) | 61-79 | |
| » Starters: Willis Hudlin vs Hod Lisenbee | Sixth | 39 out |
| Sunday, September 18 |
| » Defeated Senators (75-66), 6-4 | Griffith Stadium (4-6) | 62-79 | |
| » Starters: Joe Shaute vs Tom Zachary | Sixth | 39½ out |
| Monday, September 19 |
| » Lost to Senators (76-66), 4-1 | Griffith Stadium (4-7) | 62-80 | |
| » Starters: George Uhle vs Bump Hadley | Sixth | 40 out |
| » Major-league debuts: Babe Ganzel (Senators) |
| Wednesday, September 21 |
| » Defeated Athletics (86-59), 6-5 | Shibe Park (3-4) | 63-80 | |
| » Starters: Willis Hudlin vs Jack Quinn | Sixth | 39 out |
| Thursday, September 22 |
| » Lost to Athletics (87-59), 4-3 | Shibe Park (3-5) | 63-81 | |
| » Starters: Jake Miller vs Rube Walberg | Sixth | 40½ out |
| » Lost to Athletics (88-59), 5-2 | Shibe Park (3-6) | 63-82 | Lost 2 |
| » Starters: Hal McKain vs Eddie Rommel | Sixth | 40½ out |
| » Major-league debuts: Hal McKain (Indians) |
| Saturday, September 24 |
| » Lost to Athletics (89-59), 4-3 | Shibe Park (3-7) | 63-83 | Lost 3 |
| » Starters: Joe Shaute vs Howard Ehmke | Sixth | 41 out |
| » Defeated Athletics (89-60), 4-3 | Shibe Park (4-7) | 64-83 | |
| » Starters: Garland Buckeye vs Guy Cantrell | Sixth | 41 out |
| Sunday, September 25 |
| » Defeated White Sox (66-82), 10-1 | League Park II (35-41) | 65-83 | Won 2 |
| » Starters: Ted Blankenship vs Willis Hudlin | Sixth | 40 out |
| Monday, September 26 |
| » Lost to Tigers (80-69), 2-1 | League Park II (35-42) | 65-84 | |
| » Starters: Josh Billings vs Jake Miller | Sixth | 40½ out |
| Friday, September 30 |
| » Defeated Browns (57-92), 5-4 | Sportsman's Park III (5-4) | 66-84 | |
| » Starters: Willis Hudlin vs George Blaeholder | Sixth | 42 out |
| » Lost to Browns (58-92), 9-4 | Sportsman's Park III (5-5) | 66-85 | |
| » Starters: Willie Underhill vs Jim Wright | Sixth | 42 out |
| Sunday, October 2 |
| » Lost to Tigers (81-71), 11-5 | Tiger Stadium (4-6) | 66-86 | Lost 2 |
| » Starters: George Grant vs Josh Billings | Sixth | 43½ out |
| » Lost to Tigers (82-71), 5-4 | Tiger Stadium (4-7) | 66-87 | Lost 3 |
| » Starters: Garland Buckeye vs Rufus Smith | Sixth | 43½ out |
| Tuesday, October 4 |
| Future Indian Bob Kelly is born in Cleveland, OH. |
| Monday, October 17 |
| Future Indian Johnny Klippstein is born in Washington, DC. |
| Sunday, October 30 |
| Future Indian Joe Adcock is born in Coushatta, LA. |
| Tuesday, November 1 |
| Future Indian Vic Power is born in Arecibo, P.R. |
| Thursday, November 17 |
| Future Indian Dick Weik is born in Waterloo, IA. |
| Thursday, December 1 |
| Former Indian Danny Shay dies in Kansas City, MO at the age of 52. |
| Wednesday, December 7 |
| Future Indian Dick Donovan is born in Boston, MA. |
Game information provided by Retrosheet (www.retrosheet.org) |
