| Sunday, March 27 |
| Future Athletic Dick Rozek is born in Cedar Rapids, IA. |
| Tuesday, April 12 |
| » Lost to Yankees (1-0), 8-3 | Yankee Stadium (0-1) | 0-1 | |
| » Starters: Lefty Grove vs Waite Hoyt | Third | 1 out |
| Wednesday, April 13 |
| » Lost to Yankees (2-0), 10-4 | Yankee Stadium (0-2) | 0-2 | Lost 2 |
| » Starters: Dolly Gray vs Dutch Ruether | Sixth | 2 out |
| Thursday, April 14 |
| » Tied Yankees, 9-9 | Yankee Stadium (0-2) | 0-2 | |
| » Starters: Eddie Rommel vs Bob Shawkey | Fifth | 2 out |
| » Major-league debuts: Wilcy Moore and Julie Wera (Yankees) |
| Friday, April 15 |
| » Lost to Yankees (3-0), 6-3 | Yankee Stadium (0-3) | 0-3 | Lost 3 |
| » Starters: Howard Ehmke vs Herb Pennock | Fourth | 3 out |
| Saturday, April 16 |
| » Defeated Senators (3-1), 8-7 | Griffith Stadium (1-0) | 1-3 | |
| » Starters: Lefty Grove vs George Murray | Seventh | 3 out |
| » Major-league debuts: Bobby Burke (Senators) |
| Sunday, April 17 |
| » Defeated Senators (3-2), 13-3 | Griffith Stadium (2-0) | 2-3 | Won 2 |
| » Starters: Dolly Gray vs Garland Braxton | Sixth | 3 out |
| » Major-league debuts: Sammy West (Senators) |
| Monday, April 18 |
| » Lost to Senators (4-2), 4-0 | Griffith Stadium (2-1) | 2-4 | |
| » Starters: Rube Walberg vs Sloppy Thurston | Seventh | 4 out |
| Tuesday, April 19 |
| » Defeated Senators (4-3), 3-1 | Griffith Stadium (3-1) | 3-4 | |
| » Starters: Howard Ehmke vs Alvin Crowder | Fifth | 3 out |
| Wednesday, April 20 |
| » Defeated Yankees (6-2), 8-5 | Shibe Park (1-0) | 4-4 | Won 2 |
| » Starters: Urban Shocker vs Lefty Grove | Fifth | 2 out |
| Thursday, April 21 |
| » Lost to Yankees (7-2), 13-6 | Shibe Park (1-1) | 4-5 | |
| » Starters: Waite Hoyt vs Dolly Gray | Sixth | 3 out |
| Saturday, April 23 |
| » Defeated Yankees (7-3), 4-3 | Shibe Park (2-1) | 5-5 | |
| » Starters: Dutch Ruether vs Rube Walberg | Fifth | 2 out |
| Tuesday, April 26 |
| » Defeated Red Sox (2-9), 9-8 | Fenway Park (1-0) | 6-5 | Won 2 |
| » Starters: Howard Ehmke vs Hal Wiltse | Fourth | 1½ out |
| Future Athletic Granny Hamner is born in Richmond, VA. |
| Wednesday, April 27 |
| » Defeated Red Sox (2-10), 4-1 | Fenway Park (2-0) | 7-5 | Won 3 |
| » Starters: Lefty Grove vs Jack Russell | Third | 1 out |
| Thursday, April 28 |
| » Defeated Senators (7-6), 15-7 | Shibe Park (3-1) | 8-5 | Won 4 |
| » Starters: Alvin Crowder vs Rube Walberg | Second | ½ out |
| » Major-league debuts: Dick Coffman (Senators) |
| Friday, April 29 |
| » Defeated Senators (7-7), 8-7 | Shibe Park (4-1) | 9-5 | Won 5 |
| » Starters: Sloppy Thurston vs Dolly Gray | Second | ½ out |
| Sunday, May 1 |
| » Lost to Yankees (10-5), 7-3 | Yankee Stadium (0-4) | 9-6 | |
| » Starters: Jack Quinn vs Herb Pennock | Second | 1 out |
| Monday, May 2 |
| » Defeated Red Sox (3-13), 6-5 | Shibe Park (5-1) | 10-6 | |
| » Starters: Ted Wingfield vs Lefty Grove | Second | 1 out |
| Tuesday, May 3 |
| » Defeated Red Sox (3-14), 7-2 | Shibe Park (6-1) | 11-6 | Won 2 |
| » Starters: Slim Harriss vs Howard Ehmke | Second | 1 out |
| Thursday, May 5 |
| » Lost to Red Sox (4-14), 3-2 | Shibe Park (6-2) | 11-7 | |
| » Starters: Hal Wiltse vs Lefty Grove | Second | ½ out |
| Saturday, May 7 |
| » Lost to Indians (9-12), 11-10 | League Park II (0-1) | 11-8 | Lost 2 |
| » Starters: Rube Walberg vs Willis Hudlin | Second | 1½ out |
| » Major-league debuts: Johnny Burnett (Indians) |
| Sunday, May 8 |
| » Lost to Indians (10-12), 4-2 | League Park II (0-2) | 11-9 | Lost 3 |
| » Starters: Howard Ehmke vs Garland Buckeye | Second | 2½ out |
| Monday, May 9 |
| » Lost to Indians (11-12), 6-1 | League Park II (0-3) | 11-10 | Lost 4 |
| » Starters: Rube Walberg vs Joe Shaute | Fourth | 2½ out |
| Tuesday, May 10 |
| » Defeated Tigers (11-10), 6-3 | Tiger Stadium (1-0) | 12-10 | |
| » Starters: Lefty Grove vs Earl Whitehill | Third | 2½ out |
| Wednesday, May 11 |
| » Defeated Tigers (11-11), 3-1 | Tiger Stadium (2-0) | 13-10 | Won 2 |
| » Starters: Jack Quinn vs Ken Holloway | Third | 2½ out |
| Thursday, May 12 |
| » Lost to Tigers (12-11), 9-7 | Tiger Stadium (2-1) | 13-11 | |
| » Starters: Dolly Gray vs Rip Collins | Third | 3½ out |
| Friday, May 13 |
| » Defeated Tigers (12-12), 10-3 | Tiger Stadium (3-1) | 14-11 | |
| » Starters: Howard Ehmke vs Sam Gibson | Third | 3½ out |
| Saturday, May 14 |
| » Lost to Browns (10-13), 12-2 | Sportsman's Park III (0-1) | 14-12 | |
| » Starters: Lefty Grove vs Win Ballou | Third | 4 out |
| Sunday, May 15 |
| » Lost to Browns (11-13), 8-6 | Sportsman's Park III (0-2) | 14-13 | Lost 2 |
| » Starters: Rube Walberg vs Milt Gaston | Third | 4½ out |
| Monday, May 16 |
| » Defeated Browns (11-14), 10-8 | Sportsman's Park III (1-2) | 15-13 | |
| » Starters: Jack Quinn vs Sam Jones | Third | 4½ out |
| Tuesday, May 17 |
| » Lost to Browns (12-14), 11-4 | Sportsman's Park III (1-3) | 15-14 | |
| » Starters: Howard Ehmke vs Tom Zachary | Third | 5½ out |
| Thursday, May 19 |
| » Lost to White Sox (18-13), 3-0 | Comiskey Park I (0-1) | 15-15 | Lost 2 |
| » Starters: Lefty Grove vs Tommy Thomas | Fourth | 6½ out |
| Friday, May 20 |
| » Defeated White Sox (18-14), 12-5 | Comiskey Park I (1-1) | 16-15 | |
| » Starters: Eddie Rommel vs Ted Blankenship | Third | 5½ out |
| Saturday, May 21 |
| » Lost to White Sox (19-14), 7-5 | Comiskey Park I (1-2) | 16-16 | |
| » Starters: Rube Walberg vs Ted Lyons | Fourth | 5½ out |
| Sunday, May 22 |
| » Defeated White Sox (19-15), 6-1 | Comiskey Park I (2-2) | 17-16 | |
| » Starters: Howard Ehmke vs Red Faber | Fourth | 5½ out |
| Thursday, May 26 |
| » Defeated Red Sox (9-22), 3-1 | Fenway Park (3-0) | 18-16 | Won 2 |
| » Starters: Lefty Grove vs Hal Wiltse | Third | 5 out |
| » Lost to Red Sox (10-22), 4-3 | Fenway Park (3-1) | 18-17 | |
| » Starters: Rube Walberg vs Tony Welzer | Third | 5 out |
| Saturday, May 28 |
| » Defeated Red Sox (10-23), 8-6 | Fenway Park (4-1) | 19-17 | |
| » Starters: Howard Ehmke vs Del Lundgren | Third | 4 out |
| » Defeated Red Sox (10-24), 4-3 | Fenway Park (5-1) | 20-17 | Won 2 |
| » Starters: Jack Quinn vs Slim Harriss | Third | 4 out |
| Sunday, May 29 |
| » Defeated Senators (17-18), 6-1 | Griffith Stadium (4-1) | 21-17 | Won 3 |
| » Starters: Rube Walberg vs Alvin Crowder | Third | 4 out |
| Monday, May 30 |
| » Defeated Yankees (25-14), 9-8 | Shibe Park (7-2) | 22-17 | Won 4 |
| » Starters: George Pipgras vs Lefty Grove | Third | 4 out |
| » Lost to Yankees (26-14), 6-5 | Shibe Park (7-3) | 22-18 | |
| » Starters: Herb Pennock vs Dolly Gray | Third | 4 out |
| Tuesday, May 31 |
| » Lost to Yankees (27-14), 10-3 | Shibe Park (7-4) | 22-19 | Lost 2 |
| » Starters: Waite Hoyt vs Jack Quinn | Third | 6 out |
| » Lost to Yankees (28-14), 18-5 | Shibe Park (7-5) | 22-20 | Lost 3 |
| » Starters: Urban Shocker vs Howard Ehmke | Third | 6 out |
| » Major-league debuts: Carroll Yerkes (Athletics) |
| Wednesday, June 1 |
| » Lost to Yankees (29-14), 2-1 | Shibe Park (7-6) | 22-21 | Lost 4 |
| » Starters: Myles Thomas vs Rube Walberg | Third | 7 out |
| Thursday, June 2 |
| » Defeated Indians (21-24), 8-4 | Shibe Park (8-6) | 23-21 | |
| » Starters: Joe Shaute vs Dolly Gray | Third | 7 out |
| Friday, June 3 |
| » Lost to Indians (22-24), 3-1 | Shibe Park (8-7) | 23-22 | |
| » Starters: Jake Miller vs Jack Quinn | Third | 7 out |
| Monday, June 6 |
| » Defeated Indians (22-25), 4-1 | Shibe Park (9-7) | 24-22 | |
| » Starters: Garland Buckeye vs Howard Ehmke | Third | 7 out |
| Tuesday, June 7 |
| » Defeated Browns (22-24), 11-9 | Shibe Park (10-7) | 25-22 | Won 2 |
| » Starters: Milt Gaston vs Rube Walberg | Third | 7 out |
| Wednesday, June 8 |
| » Defeated Browns (22-25), 7-5 | Shibe Park (11-7) | 26-22 | Won 3 |
| » Starters: Lefty Stewart vs Jack Quinn | Third | 7 out |
| Thursday, June 9 |
| » Defeated Browns (22-26), 9-3 | Shibe Park (12-7) | 27-22 | Won 4 |
| » Starters: Ernie Nevers vs Rube Walberg | Third | 7 out |
| Friday, June 10 |
| » Defeated Browns (22-27), 4-3 | Shibe Park (13-7) | 28-22 | Won 5 |
| » Starters: Ernie Wingard vs Eddie Rommel | Third | 6 out |
| Saturday, June 11 |
| » Lost to Tigers (23-26), 6-5 | Shibe Park (13-8) | 28-23 | |
| » Starters: Earl Whitehill vs Howard Ehmke | Third | 7 out |
| Monday, June 13 |
| » Defeated Tigers (24-27), 7-6 | Shibe Park (14-8) | 29-23 | |
| » Starters: Ken Holloway vs Rube Walberg | Third | 6½ out |
| Wednesday, June 15 |
| » Lost to White Sox (33-23), 6-4 | Shibe Park (14-9) | 29-24 | |
| » Starters: Ted Lyons vs Jack Quinn | Third | 7 out |
| Thursday, June 16 |
| » Lost to White Sox (34-23), 4-0 | Shibe Park (14-10) | 29-25 | Lost 2 |
| » Starters: Sarge Connally vs Howard Ehmke | Third | 8 out |
| Friday, June 17 |
| » Defeated White Sox (34-24), 8-3 | Shibe Park (15-10) | 30-25 | |
| » Starters: Charlie Barnabe vs Rube Walberg | Third | 8 out |
| Saturday, June 18 |
| » Defeated White Sox (34-25), 6-2 | Shibe Park (16-10) | 31-25 | Won 2 |
| » Starters: Tommy Thomas vs Lefty Grove | Third | 8 out |
| Former Athletic Jack Harper dies in Halstead, KS at the age of 34. |
| Tuesday, June 21 |
| » Lost to Senators (29-26), 5-4 | Shibe Park (16-11) | 31-26 | |
| » Starters: Sloppy Thurston vs Eddie Rommel | Third | 9 out |
| » Defeated Senators (29-27), 8-2 | Shibe Park (17-11) | 32-26 | |
| » Starters: Walter Johnson vs Rube Walberg | Third | 9 out |
| Wednesday, June 22 |
| » Lost to Senators (30-27), 4-2 | Shibe Park (17-12) | 32-27 | |
| » Starters: Hod Lisenbee vs Jack Quinn | Third | 10 out |
| » Defeated Senators (30-28), 13-7 | Shibe Park (18-12) | 33-27 | |
| » Starters: Alvin Crowder vs Dolly Gray | Third | 10 out |
| Thursday, June 23 |
| » Defeated Senators (30-29), 4-1 | Shibe Park (19-12) | 34-27 | Won 2 |
| » Starters: Firpo Marberry vs Lefty Willis | Second | 10 out |
| Saturday, June 25 |
| » Defeated Yankees (44-18), 7-6 | Yankee Stadium (1-4) | 35-27 | Won 3 |
| » Starters: Lefty Grove vs Herb Pennock | Second | 8 out |
| » Defeated Yankees (44-19), 4-2 | Yankee Stadium (2-4) | 36-27 | Won 4 |
| » Starters: Rube Walberg vs Waite Hoyt | Second | 8 out |
| Sunday, June 26 |
| » Defeated Yankees (44-20), 4-2 | Yankee Stadium (3-4) | 37-27 | Won 5 |
| » Starters: Jack Quinn vs Myles Thomas | Second | 8 out |
| » Lost to Yankees (45-20), 7-3 | Yankee Stadium (3-5) | 37-28 | |
| » Starters: Dolly Gray vs Wilcy Moore | Second | 8 out |
| Monday, June 27 |
| » Lost to Yankees (46-20), 6-2 | Yankee Stadium (3-6) | 37-29 | Lost 2 |
| » Starters: Howard Ehmke vs Dutch Ruether | Second | 9 out |
| Tuesday, June 28 |
| » Lost to Yankees (47-20), 9-8 | Yankee Stadium (3-7) | 37-30 | Lost 3 |
| » Starters: Rube Walberg vs Urban Shocker | Second | 10 out |
| Wednesday, June 29 |
| » Lost to Senators (36-29), 5-3 | Griffith Stadium (4-2) | 37-31 | Lost 4 |
| » Starters: Lefty Grove vs Sloppy Thurston | Fourth | 11 out |
| Thursday, June 30 |
| » Lost to Senators (37-29), 6-5 | Griffith Stadium (4-3) | 37-32 | Lost 5 |
| » Starters: Neal Baker vs Hod Lisenbee | Fourth | 12 out |
| Friday, July 1 |
| » Lost to Senators (38-29), 2-1 | Griffith Stadium (4-4) | 37-33 | Lost 6 |
| » Starters: Jack Quinn vs Bump Hadley | Fifth | 13 out |
| Saturday, July 2 |
| » Lost to Senators (39-29), 4-2 | Griffith Stadium (4-5) | 37-34 | Lost 7 |
| » Starters: Rube Walberg vs Bobby Burke | Fifth | 14 out |
| Monday, July 4 |
| » Defeated Red Sox (15-54), 10-2 | Fenway Park (6-1) | 38-34 | |
| » Starters: Lefty Grove vs Red Ruffing | Fifth | 14½ out |
| » Lost to Red Sox (16-54), 11-3 | Fenway Park (6-2) | 38-35 | |
| » Starters: Howard Ehmke vs Hal Wiltse | Fifth | 14½ out |
| Tuesday, July 5 |
| » Lost to Red Sox (17-54), 6-5 | Fenway Park (6-3) | 38-36 | Lost 2 |
| » Starters: Neal Baker vs Tony Welzer | Fifth | 15½ out |
| Wednesday, July 6 |
| » Defeated Red Sox (17-55), 5-1 | Fenway Park (7-3) | 39-36 | |
| » Starters: Jack Quinn vs Del Lundgren | Fifth | 14½ out |
| » Defeated Red Sox (17-56), 7-6 | Fenway Park (8-3) | 40-36 | Won 2 |
| » Starters: Rube Walberg vs Danny MacFayden | Fifth | 14½ out |
| Friday, July 8 |
| » Defeated Browns (30-44), 7-5 | Sportsman's Park III (2-3) | 41-36 | Won 3 |
| » Starters: Lefty Grove vs Sam Jones | Fifth | 14 out |
| Saturday, July 9 |
| » Lost to Browns (31-44), 7-5 | Sportsman's Park III (2-4) | 41-37 | |
| » Starters: Lefty Willis vs Milt Gaston | Fifth | 14½ out |
| Sunday, July 10 |
| » Defeated Browns (31-45), 14-11 | Sportsman's Park III (3-4) | 42-37 | |
| » Starters: Rube Walberg vs Alvin Crowder | Fifth | 13½ out |
| Monday, July 11 |
| » Defeated Browns (31-46), 7-6 | Sportsman's Park III (4-4) | 43-37 | Won 2 |
| » Starters: Jack Quinn vs Elam Vangilder | Fourth | 13½ out |
| Tuesday, July 12 |
| » Lost to White Sox (46-37), 8-5 | Comiskey Park I (2-3) | 43-38 | |
| » Starters: Eddie Rommel vs Sarge Connally | Fifth | 14½ out |
| Wednesday, July 13 |
| » Defeated White Sox (46-38), 7-5 | Comiskey Park I (3-3) | 44-38 | |
| » Starters: Lefty Grove vs Ted Lyons | Fifth | 14½ out |
| Friday, July 15 |
| » Defeated White Sox (46-39), 3-1 | Comiskey Park I (4-3) | 45-38 | Won 2 |
| » Starters: Jack Quinn vs Elmer Jacobs | Third | 13½ out |
| » Defeated White Sox (46-40), 13-10 | Comiskey Park I (5-3) | 46-38 | Won 3 |
| » Starters: Rube Walberg vs Tommy Thomas | Third | 13½ out |
| Saturday, July 16 |
| » Defeated Tigers (44-38), 9-3 | Tiger Stadium (4-1) | 47-38 | Won 4 |
| » Starters: Eddie Rommel vs Earl Whitehill | Third | 13½ out |
| Sunday, July 17 |
| » Lost to Tigers (45-38), 5-4 | Tiger Stadium (4-2) | 47-39 | |
| » Starters: Dolly Gray vs Lil Stoner | Third | 14½ out |
| Monday, July 18 |
| » Lost to Tigers (46-38), 5-3 | Tiger Stadium (4-3) | 47-40 | Lost 2 |
| » Starters: Lefty Grove vs Sam Gibson | Fourth | 15½ out |
| Tuesday, July 19 |
| » Lost to Tigers (47-38), 10-9 | Tiger Stadium (4-4) | 47-41 | Lost 3 |
| » Starters: Rube Walberg vs Ken Holloway | Fourth | 16½ out |
| Thursday, July 21 |
| » Defeated Indians (37-54), 8-3 | League Park II (1-3) | 48-41 | |
| » Starters: Jack Quinn vs Joe Shaute | Fourth | 16½ out |
| Sunday, July 24 |
| » Lost to Indians (38-54), 9-6 | League Park II (1-4) | 48-42 | |
| » Starters: Eddie Rommel vs Garland Buckeye | Fourth | 18 out |
| » Lost to Indians (39-54), 5-2 | League Park II (1-5) | 48-43 | Lost 2 |
| » Starters: Rube Walberg vs Jake Miller | Fourth | 18 out |
| Monday, July 25 |
| » Defeated Tigers (49-40), 6-5 | Shibe Park (20-12) | 49-43 | |
| » Starters: Ken Holloway vs Buzz Wetzel | Fourth | 17½ out |
| Tuesday, July 26 |
| » Lost to Tigers (50-40), 10-4 | Shibe Park (20-13) | 49-44 | |
| » Starters: Rip Collins vs Lefty Grove | Fourth | 18½ out |
| » Defeated Tigers (50-41), 5-2 | Shibe Park (21-13) | 50-44 | |
| » Starters: Ownie Carroll vs Jack Quinn | Fourth | 18½ out |
| Wednesday, July 27 |
| » Lost to Tigers (51-41), 3-1 | Shibe Park (21-14) | 50-45 | |
| » Starters: Earl Whitehill vs Dolly Gray | Fourth | 19½ out |
| Thursday, July 28 |
| » Lost to Tigers (52-41), 5-2 | Shibe Park (21-15) | 50-46 | Lost 2 |
| » Starters: Sam Gibson vs Eddie Rommel | Fourth | 20½ out |
| Friday, July 29 |
| » Lost to White Sox (50-50), 6-4 | Shibe Park (21-16) | 50-47 | Lost 3 |
| » Starters: Tommy Thomas vs Jing Johnson | Fourth | 20½ out |
| Saturday, July 30 |
| » Defeated White Sox (50-51), 5-3 | Shibe Park (22-16) | 51-47 | |
| » Starters: Sarge Connally vs Lefty Grove | Fourth | 21 out |
| Sunday, July 31 |
| Future Athletic Billy Shantz is born in Pottstown, PA. |
| Tuesday, August 2 |
| » Lost to White Sox (51-51), 7-4 | Shibe Park (22-17) | 51-48 | |
| » Starters: Ted Lyons vs Jack Quinn | Fourth | 20½ out |
| » Defeated White Sox (51-52), 6-5 | Shibe Park (23-17) | 52-48 | |
| » Starters: Ted Blankenship vs Howard Ehmke | Fourth | 20½ out |
| Wednesday, August 3 |
| » Defeated Indians (42-60), 9-2 | Shibe Park (24-17) | 53-48 | Won 2 |
| » Starters: Joe Shaute vs Eddie Rommel | Fourth | 19½ out |
| » Defeated Indians (42-61), 7-4 | Shibe Park (25-17) | 54-48 | Won 3 |
| » Starters: Willis Hudlin vs Rube Walberg | Fourth | 19½ out |
| Thursday, August 4 |
| » Lost to Indians (43-61), 3-0 | Shibe Park (25-18) | 54-49 | |
| » Starters: Garland Buckeye vs Lefty Grove | Fourth | 19½ out |
| Saturday, August 6 |
| » Defeated Browns (40-63), 5-4 | Shibe Park (26-18) | 55-49 | |
| » Starters: Win Ballou vs Howard Ehmke | Fourth | 19½ out |
| » Lost to Browns (41-63), 2-0 | Shibe Park (26-19) | 55-50 | |
| » Starters: Alvin Crowder vs Jack Quinn | Fourth | 19½ out |
| Tuesday, August 9 |
| » Defeated Yankees (76-32), 8-1 | Shibe Park (27-19) | 56-50 | |
| » Starters: Dutch Ruether vs Rube Walberg | Fourth | 19 out |
| Wednesday, August 10 |
| » Defeated Red Sox (35-71), 12-2 | Shibe Park (28-19) | 57-50 | Won 2 |
| » Starters: Tony Welzer vs Lefty Grove | Fourth | 19 out |
| Thursday, August 11 |
| » Defeated Red Sox (35-72), 4-0 | Shibe Park (29-19) | 58-50 | Won 3 |
| » Starters: Danny MacFayden vs Howard Ehmke | Fourth | 18½ out |
| » Lost to Red Sox (36-72), 2-0 | Shibe Park (29-20) | 58-51 | |
| » Starters: Slim Harriss vs Jack Quinn | Fourth | 18½ out |
| Friday, August 12 |
| » Defeated Red Sox (36-73), 7-1 | Shibe Park (30-20) | 59-51 | |
| » Starters: Hal Wiltse vs Eddie Rommel | Fourth | 18 out |
| Saturday, August 13 |
| » Defeated Red Sox (36-74), 6-2 | Shibe Park (31-20) | 60-51 | Won 2 |
| » Starters: Red Ruffing vs Rube Walberg | Fourth | 18 out |
| Tuesday, August 16 |
| » Defeated Indians (47-65), 6-3 | League Park II (2-5) | 61-51 | Won 3 |
| » Starters: Howard Ehmke vs Jake Miller | Fourth | 18 out |
| » Defeated Indians (47-66), 8-0 | League Park II (3-5) | 62-51 | Won 4 |
| » Starters: Jack Quinn vs Garland Buckeye | Fourth | 18 out |
| Wednesday, August 17 |
| » Defeated Indians (47-67), 4-1 | League Park II (4-5) | 63-51 | Won 5 |
| » Starters: Lefty Grove vs Willis Hudlin | Fourth | 18 out |
| Thursday, August 18 |
| » Lost to Indians (48-67), 2-1 | League Park II (4-6) | 63-52 | |
| » Starters: Eddie Rommel vs Joe Shaute | Fourth | 19 out |
| Friday, August 19 |
| » Defeated Indians (48-68), 5-3 | League Park II (5-6) | 64-52 | |
| » Starters: Rube Walberg vs Dutch Levsen | Fourth | 18 out |
| Saturday, August 20 |
| » Defeated White Sox (54-62), 5-2 | Comiskey Park I (6-3) | 65-52 | Won 2 |
| » Starters: Howard Ehmke vs Tommy Thomas | Fourth | 17 out |
| Sunday, August 21 |
| » Defeated White Sox (54-63), 8-6 | Comiskey Park I (7-3) | 66-52 | Won 3 |
| » Starters: Eddie Rommel vs Elmer Jacobs | Fourth | 16 out |
| Monday, August 22 |
| » Lost to White Sox (55-63), 6-3 | Comiskey Park I (7-4) | 66-53 | |
| » Starters: Jack Quinn vs Ted Lyons | Fourth | 16 out |
| Wednesday, August 24 |
| » Defeated Browns (47-70), 4-3 | Sportsman's Park III (5-4) | 67-53 | |
| » Starters: Rube Walberg vs Ernie Wingard | Third | 16 out |
| Thursday, August 25 |
| » Defeated Browns (47-71), 6-1 | Sportsman's Park III (6-4) | 68-53 | Won 2 |
| » Starters: Eddie Rommel vs Win Ballou | Third | 16 out |
| Friday, August 26 |
| » Defeated Browns (47-72), 7-0 | Sportsman's Park III (7-4) | 69-53 | Won 3 |
| » Starters: Dolly Gray vs Milt Gaston | Third | 16 out |
| Saturday, August 27 |
| » Defeated Tigers (68-52), 8-7 | Tiger Stadium (5-4) | 70-53 | Won 4 |
| » Starters: Howard Ehmke vs Josh Billings | Second | 16 out |
| Sunday, August 28 |
| » Defeated Tigers (68-53), 9-5 | Tiger Stadium (6-4) | 71-53 | Won 5 |
| » Starters: Lefty Grove vs Ownie Carroll | Second | 16 out |
| Monday, August 29 |
| » Defeated Tigers (68-54), 5-0 | Tiger Stadium (7-4) | 72-53 | Won 6 |
| » Starters: Jack Quinn vs Earl Whitehill | Second | 16 out |
| Wednesday, August 31 |
| » Lost to Senators (67-57), 5-3 | Griffith Stadium (4-6) | 72-54 | |
| » Starters: Howard Ehmke vs Bump Hadley | Second | 17 out |
| Thursday, September 1 |
| » Major-league debuts: Carl Reynolds (White Sox) |
| Future Athletic Cloyd Boyer is born in Alba, MO. |
| Friday, September 2 |
| » Lost to Yankees (90-37), 12-2 | Shibe Park (31-21) | 72-55 | Lost 2 |
| » Starters: Waite Hoyt vs Rube Walberg | Second | 18 out |
| Saturday, September 3 |
| » Defeated Yankees (90-38), 1-0 | Shibe Park (32-21) | 73-55 | |
| » Starters: Wilcy Moore vs Lefty Grove | Second | 17 out |
| Monday, September 5 |
| » Defeated Senators (68-59), 2-1 | Shibe Park (33-21) | 74-55 | Won 2 |
| » Starters: Tom Zachary vs Howard Ehmke | Second | 16 out |
| » Defeated Senators (68-60), 3-0 | Shibe Park (34-21) | 75-55 | Won 3 |
| » Starters: Bump Hadley vs Jack Quinn | Second | 16 out |
| Tuesday, September 6 |
| » Lost to Senators (69-60), 14-9 | Shibe Park (34-22) | 75-56 | |
| » Starters: Firpo Marberry vs Rube Walberg | Second | 16 out |
| » Defeated Senators (69-61), 4-0 | Shibe Park (35-22) | 76-56 | |
| » Starters: Hod Lisenbee vs Eddie Rommel | Second | 16 out |
| Former Athletic Lave Cross dies in Toledo, OH at the age of 62. |
| Thursday, September 8 |
| » Defeated Tigers (70-62), 9-1 | Shibe Park (36-22) | 77-56 | Won 2 |
| » Starters: Lil Stoner vs Lefty Grove | Second | 16½ out |
| Friday, September 9 |
| » Lost to Tigers (71-62), 5-2 | Shibe Park (36-23) | 77-57 | |
| » Starters: Earl Whitehill vs Howard Ehmke | Second | 17½ out |
| Saturday, September 10 |
| » Defeated Tigers (71-63), 6-4 | Shibe Park (37-23) | 78-57 | |
| » Starters: Ownie Carroll vs Jack Quinn | Second | 17½ out |
| Monday, September 12 |
| » Defeated Tigers (71-64), 5-4 | Shibe Park (38-23) | 79-57 | Won 2 |
| » Starters: Sam Gibson vs Eddie Rommel | Second | 16½ out |
| Tuesday, September 13 |
| » Defeated White Sox (65-71), 15-5 | Shibe Park (39-23) | 80-57 | Won 3 |
| » Starters: Sarge Connally vs Lefty Grove | Second | 17 out |
| Wednesday, September 14 |
| » Defeated White Sox (65-72), 5-4 | Shibe Park (40-23) | 81-57 | Won 4 |
| » Starters: Tommy Thomas vs Howard Ehmke | Second | 17 out |
| Thursday, September 15 |
| » Defeated White Sox (65-73), 5-4 | Shibe Park (41-23) | 82-57 | Won 5 |
| » Starters: Ted Lyons vs Jack Quinn | Second | 16 out |
| Friday, September 16 |
| » Defeated Browns (56-84), 6-3 | Shibe Park (42-23) | 83-57 | Won 6 |
| » Starters: Ernie Wingard vs Jing Johnson | Second | 16 out |
| Saturday, September 17 |
| » Lost to Browns (57-84), 6-0 | Shibe Park (42-24) | 83-58 | |
| » Starters: Elam Vangilder vs Rube Walberg | Second | 17 out |
| » Defeated Browns (57-85), 13-0 | Shibe Park (43-24) | 84-58 | |
| » Starters: Sam Jones vs Eddie Rommel | Second | 17 out |
| Monday, September 19 |
| » Major-league debuts: Babe Ganzel (Senators) |
| Tuesday, September 20 |
| » Defeated Browns (57-86), 4-1 | Shibe Park (44-24) | 85-58 | Won 2 |
| » Starters: Alvin Crowder vs Lefty Grove | Second | 17 out |
| » Defeated Browns (57-87), 7-3 | Shibe Park (45-24) | 86-58 | Won 3 |
| » Starters: Milt Gaston vs Howard Ehmke | Second | 17 out |
| Wednesday, September 21 |
| » Lost to Indians (63-80), 6-5 | Shibe Park (45-25) | 86-59 | |
| » Starters: Willis Hudlin vs Jack Quinn | Second | 17 out |
| Thursday, September 22 |
| » Defeated Indians (63-81), 4-3 | Shibe Park (46-25) | 87-59 | |
| » Starters: Jake Miller vs Rube Walberg | Second | 16½ out |
| » Defeated Indians (63-82), 5-2 | Shibe Park (47-25) | 88-59 | Won 2 |
| » Starters: Hal McKain vs Eddie Rommel | Second | 16½ out |
| » Major-league debuts: Hal McKain (Indians) |
| Saturday, September 24 |
| » Defeated Indians (63-83), 4-3 | Shibe Park (48-25) | 89-59 | Won 3 |
| » Starters: Joe Shaute vs Howard Ehmke | Second | 17 out |
| » Lost to Indians (64-83), 4-3 | Shibe Park (48-26) | 89-60 | |
| » Starters: Garland Buckeye vs Guy Cantrell | Second | 17 out |
| Tuesday, September 27 |
| » Lost to Yankees (107-44), 7-4 | Yankee Stadium (3-8) | 89-61 | Lost 2 |
| » Starters: Rube Walberg vs Herb Pennock | Second | 17½ out |
| Thursday, September 29 |
| » Lost to Red Sox (51-101), 6-1 | Shibe Park (48-27) | 89-62 | Lost 3 |
| » Starters: Herb Bradley vs Guy Cantrell | Second | 18½ out |
| Saturday, October 1 |
| » Defeated Red Sox (51-102), 10-2 | Shibe Park (49-27) | 90-62 | |
| » Starters: Frank Bennett vs Jing Johnson | Second | 18½ out |
| » Defeated Red Sox (51-103), 3-2 | Shibe Park (50-27) | 91-62 | Won 2 |
| » Starters: John Wilson vs Dolly Gray | Second | 18½ out |
| Sunday, October 2 |
| » Lost to Senators (85-69), 9-5 | Griffith Stadium (4-7) | 91-63 | |
| » Starters: Ike Powers vs Paul Hopkins | Second | 19 out |
| Monday, October 3 |
| Future Athletic Bill Harrington is born in Sanford, NC. |
| Sunday, December 25 |
| Future Athletic Nellie Fox is born in St. Thomas, PA. |
Game information provided by Retrosheet (www.retrosheet.org) |
