| Tuesday, February 16 |
| Future White Sox Howie Judson is born in Hebron, IL. |
| Thursday, March 4 |
| Future White Sox Cass Michaels is born in Detroit, MI. |
| Thursday, March 18 |
| Future White Sox Dick Littlefield is born in Detroit, MI. |
| Monday, March 22 |
| Future White Sox Billy Goodman is born in Concord, NC. |
| Tuesday, April 13 |
| » Defeated Browns (0-1), 5-1 | Comiskey Park I (1-0) | 1-0 | |
| » Starters: Milt Gaston vs Ted Lyons | First | -- |
| Wednesday, April 14 |
| » Major-league debuts: Nick Cullop (Yankees) |
| Thursday, April 15 |
| » Defeated Browns (0-2), 11-4 | Comiskey Park I (2-0) | 2-0 | Won 2 |
| » Starters: Tom Zachary vs Ted Blankenship | First | -- |
| Friday, April 16 |
| » Defeated Browns (0-3), 5-1 | Comiskey Park I (3-0) | 3-0 | Won 3 |
| » Starters: Charlie Robertson vs Red Faber | First | -- |
| Saturday, April 17 |
| » Lost to Indians (2-1), 2-0 | Comiskey Park I (3-1) | 3-1 | |
| » Starters: Jake Miller vs Tommy Thomas | First | -- |
| » Major-league debuts: Bill Hunnefield and Tommy Thomas (White Sox) |
| Sunday, April 18 |
| » Defeated Indians (2-2), 5-1 | Comiskey Park I (4-1) | 4-1 | |
| » Starters: George Uhle vs Ted Lyons | First | -- |
| Monday, April 19 |
| » Lost to Indians (3-2), 5-1 | Comiskey Park I (4-2) | 4-2 | |
| » Starters: Sherry Smith vs Ted Blankenship | First | -- |
| Tuesday, April 20 |
| » Lost to Indians (4-2), 9-5 | Comiskey Park I (4-3) | 4-3 | Lost 2 |
| » Starters: Joe Shaute vs Sloppy Thurston | Second | ½ out |
| Wednesday, April 21 |
| » Lost to Browns (2-6), 5-1 | Sportsman's Park III (0-1) | 4-4 | Lost 3 |
| » Starters: Red Faber vs Tom Zachary | Third | 1½ out |
| Thursday, April 22 |
| » Defeated Browns (2-7), 11-7 | Sportsman's Park III (1-1) | 5-4 | |
| » Starters: Ted Blankenship vs Joe Giard | Fourth | 1 out |
| Friday, April 23 |
| » Lost to Browns (3-7), 2-1 | Sportsman's Park III (1-2) | 5-5 | |
| » Starters: Ted Lyons vs Milt Gaston | Fifth | 2 out |
| Saturday, April 24 |
| » Defeated Browns (3-8), 7-4 | Sportsman's Park III (2-2) | 6-5 | |
| » Starters: Tommy Thomas vs Elam Vangilder | Third | 2 out |
| Sunday, April 25 |
| » Defeated Tigers (4-6), 4-2 | Tiger Stadium (1-0) | 7-5 | Won 2 |
| » Starters: Red Faber vs Augie Johns | Third | 1½ out |
| Monday, April 26 |
| » Defeated Tigers (4-7), 5-1 | Tiger Stadium (2-0) | 8-5 | Won 3 |
| » Starters: Ted Blankenship vs Sam Gibson | Second | 1 out |
| Tuesday, April 27 |
| » Lost to Tigers (5-7), 8-7 | Tiger Stadium (2-1) | 8-6 | |
| » Starters: Ted Lyons vs Ken Holloway | Second | 2 out |
| Wednesday, April 28 |
| » Defeated Tigers (5-8), 9-5 | Tiger Stadium (3-1) | 9-6 | |
| » Starters: Tommy Thomas vs Clyde Barfoot | Second | 2 out |
| Thursday, April 29 |
| » Defeated Indians (10-4), 7-3 | League Park II (1-0) | 10-6 | Won 2 |
| » Starters: Dixie Leverett vs Dutch Levsen | Third | 2 out |
| Friday, April 30 |
| » Defeated Indians (10-5), 3-2 | League Park II (2-0) | 11-6 | Won 3 |
| » Starters: Ted Lyons vs Sherry Smith | Third | 2 out |
| Saturday, May 1 |
| » Defeated Indians (10-6), 9-6 | League Park II (3-0) | 12-6 | Won 4 |
| » Starters: Red Faber vs Joe Shaute | Second | 2 out |
| Sunday, May 2 |
| » Defeated Indians (10-7), 8-3 | League Park II (4-0) | 13-6 | Won 5 |
| » Starters: Ted Blankenship vs Garland Buckeye | Second | 1½ out |
| Monday, May 3 |
| » Lost to Tigers (8-10), 3-1 | Comiskey Park I (4-4) | 13-7 | |
| » Starters: Earl Whitehill vs Sloppy Thurston | Second | 1½ out |
| Tuesday, May 4 |
| » Defeated Tigers (8-11), 4-2 | Comiskey Park I (5-4) | 14-7 | |
| » Starters: Ed Wells vs Ted Lyons | Second | 1½ out |
| Wednesday, May 5 |
| » Lost to Tigers (9-11), 14-7 | Comiskey Park I (5-5) | 14-8 | |
| » Starters: Ken Holloway vs Tommy Thomas | Second | 1½ out |
| Friday, May 7 |
| » Lost to Senators (15-9), 8-2 | Griffith Stadium (0-1) | 14-9 | Lost 2 |
| » Starters: Dixie Leverett vs Walter Johnson | Third | 1 out |
| Saturday, May 8 |
| » Defeated Senators (15-10), 11-5 | Griffith Stadium (1-1) | 15-9 | |
| » Starters: Ted Blankenship vs Curly Ogden | Second | 1 out |
| Sunday, May 9 |
| » Lost to Senators (16-10), 6-5 | Griffith Stadium (1-2) | 15-10 | |
| » Starters: Ted Lyons vs Alex Ferguson | Third | ½ out |
| Monday, May 10 |
| » Defeated Senators (16-11), 2-0 | Griffith Stadium (2-2) | 16-10 | |
| » Starters: Sloppy Thurston vs Stan Coveleski | Second | 1 out |
| Tuesday, May 11 |
| » Lost to Athletics (14-12), 6-2 | Shibe Park (0-1) | 16-11 | |
| » Starters: Red Faber vs Lefty Grove | Third | 1½ out |
| Wednesday, May 12 |
| » Lost to Athletics (15-12), 4-3 | Shibe Park (0-2) | 16-12 | Lost 2 |
| » Starters: Ted Blankenship vs Slim Harriss | Fourth | 1½ out |
| Thursday, May 13 |
| » Defeated Athletics (15-13), 10-2 | Shibe Park (1-2) | 17-12 | |
| » Starters: Ted Lyons vs Jack Quinn | Third | 1½ out |
| Friday, May 14 |
| » Lost to Athletics (16-13), 6-5 | Shibe Park (1-3) | 17-13 | |
| » Starters: Sloppy Thurston vs Fred Heimach | Third | 2½ out |
| Saturday, May 15 |
| » Lost to Yankees (19-9), 10-1 | Yankee Stadium (0-1) | 17-14 | Lost 2 |
| » Starters: Red Faber vs Herb Pennock | Fourth | 3½ out |
| Monday, May 17 |
| » Lost to Yankees (20-9), 5-3 | Yankee Stadium (0-2) | 17-15 | Lost 3 |
| » Starters: Ted Blankenship vs Urban Shocker | Fifth | 4½ out |
| Tuesday, May 18 |
| » Lost to Yankees (21-9), 5-3 | Yankee Stadium (0-3) | 17-16 | Lost 4 |
| » Starters: Sloppy Thurston vs Sam Jones | Fifth | 5½ out |
| Wednesday, May 19 |
| » Defeated Red Sox (9-21), 9-7 | Fenway Park (1-0) | 18-16 | |
| » Starters: Ted Lyons vs Hal Wiltse | Fifth | 5½ out |
| Thursday, May 20 |
| » Defeated Red Sox (9-22), 13-4 | Fenway Park (2-0) | 19-16 | Won 2 |
| » Starters: Dixie Leverett vs Ted Wingfield | Fifth | 5½ out |
| Friday, May 21 |
| » Lost to Red Sox (10-22), 8-7 | Fenway Park (2-1) | 19-17 | |
| » Starters: Ted Blankenship vs Paul Zahniser | Fifth | 6½ out |
| Saturday, May 22 |
| » Lost to Red Sox (11-22), 14-8 | Fenway Park (2-2) | 19-18 | Lost 2 |
| » Starters: Sloppy Thurston vs Howard Ehmke | Fifth | 7½ out |
| Sunday, May 23 |
| » Defeated Indians (20-15), 1-0 | League Park II (5-0) | 20-18 | |
| » Starters: Ted Lyons vs Sherry Smith | Fifth | 7½ out |
| Monday, May 24 |
| » Defeated Tigers (18-18), 10-4 | Tiger Stadium (4-1) | 21-18 | Won 2 |
| » Starters: Tommy Thomas vs Augie Johns | Fifth | 7½ out |
| Future White Sox Willie Miranda is born in Velasco, Cuba. |
| Tuesday, May 25 |
| » Lost to Tigers (19-18), 9-2 | Tiger Stadium (4-2) | 21-19 | |
| » Starters: Ted Blankenship vs Lil Stoner | Fifth | 9 out |
| Thursday, May 27 |
| » Defeated Tigers (20-19), 5-4 | Comiskey Park I (6-5) | 22-19 | |
| » Starters: Ken Holloway vs Ted Lyons | Fourth | 9 out |
| Friday, May 28 |
| » Lost to Tigers (21-19), 6-3 | Comiskey Park I (6-6) | 22-20 | |
| » Starters: Augie Johns vs Sloppy Thurston | Fourth | 8½ out |
| Saturday, May 29 |
| » Lost to Tigers (22-19), 2-1 | Comiskey Park I (6-7) | 22-21 | Lost 2 |
| » Starters: Lil Stoner vs Tommy Thomas | Fifth | 8½ out |
| Sunday, May 30 |
| » Defeated Tigers (22-20), 6-3 | Comiskey Park I (7-7) | 23-21 | |
| » Starters: Hooks Dauss vs Red Faber | Fifth | 8½ out |
| Monday, May 31 |
| » Defeated Indians (21-22), 3-1 | League Park II (6-0) | 24-21 | Won 2 |
| » Starters: Ted Lyons vs Jake Miller | Fifth | 8½ out |
| » Lost to Indians (22-22), 5-4 | League Park II (6-1) | 24-22 | |
| » Starters: Ted Blankenship vs Joe Shaute | Fifth | 8½ out |
| Tuesday, June 1 |
| Future White Sox Ray Moore is born in Meadows, MD. |
| Wednesday, June 2 |
| » Defeated Browns (15-31), 6-5 | Sportsman's Park III (3-2) | 25-22 | |
| » Starters: Tommy Thomas vs Milt Gaston | Third | 9 out |
| Friday, June 4 |
| » Lost to Browns (16-31), 3-0 | Sportsman's Park III (3-3) | 25-23 | |
| » Starters: Jim Joe Edwards vs Tom Zachary | Fourth | 10 out |
| Saturday, June 5 |
| » Defeated Red Sox (13-33), 8-2 | Comiskey Park I (8-7) | 26-23 | |
| » Starters: Howard Ehmke vs Ted Lyons | Fourth | 9 out |
| Sunday, June 6 |
| » Lost to Red Sox (14-33), 4-3 | Comiskey Park I (8-8) | 26-24 | |
| » Starters: Paul Zahniser vs Ted Blankenship | Fourth | 10 out |
| Monday, June 7 |
| » Defeated Red Sox (14-34), 10-5 | Comiskey Park I (9-8) | 27-24 | |
| » Starters: Red Ruffing vs Tommy Thomas | Third | 9 out |
| Tuesday, June 8 |
| » Defeated Athletics (30-23), 1-0 | Comiskey Park I (10-8) | 28-24 | Won 2 |
| » Starters: Lefty Grove vs Red Faber | Third | 9 out |
| Wednesday, June 9 |
| » Defeated Athletics (30-24), 4-1 | Comiskey Park I (11-8) | 29-24 | Won 3 |
| » Starters: Dolly Gray vs Tommy Thomas | Third | 9 out |
| Thursday, June 10 |
| » Lost to Athletics (31-24), 6-0 | Comiskey Park I (11-9) | 29-25 | |
| » Starters: Jack Quinn vs Ted Lyons | Third | 10 out |
| Saturday, June 12 |
| » Lost to Senators (27-25), 7-4 | Comiskey Park I (11-10) | 29-26 | Lost 2 |
| » Starters: Walter Johnson vs Ted Blankenship | Third | 10½ out |
| Sunday, June 13 |
| » Defeated Senators (27-26), 3-0 | Comiskey Park I (12-10) | 30-26 | |
| » Starters: Dutch Ruether vs Tommy Thomas | Third | 10½ out |
| Tuesday, June 15 |
| » Defeated Senators (27-27), 4-1 | Comiskey Park I (13-10) | 31-26 | Won 2 |
| » Starters: Stan Coveleski vs Red Faber | Second | 10 out |
| Wednesday, June 16 |
| » Defeated Senators (27-28), 3-2 | Comiskey Park I (14-10) | 32-26 | Won 3 |
| » Starters: Walter Johnson vs Ted Lyons | Second | 9½ out |
| Thursday, June 17 |
| » Defeated Yankees (41-17), 6-2 | Comiskey Park I (15-10) | 33-26 | Won 4 |
| » Starters: Waite Hoyt vs Ted Blankenship | Second | 8½ out |
| Friday, June 18 |
| » Lost to Yankees (42-17), 10-2 | Comiskey Park I (15-11) | 33-27 | |
| » Starters: Herb Pennock vs Tommy Thomas | Third | 9½ out |
| Saturday, June 19 |
| » Lost to Yankees (43-17), 6-5 | Comiskey Park I (15-12) | 33-28 | Lost 2 |
| » Starters: Myles Thomas vs Jim Joe Edwards | Third | 10½ out |
| Sunday, June 20 |
| » Defeated Yankees (43-18), 4-3 | Comiskey Park I (16-12) | 34-28 | |
| » Starters: Urban Shocker vs Red Faber | Second | 9½ out |
| Monday, June 21 |
| » Lost to Indians (35-28), 5-2 | Comiskey Park I (16-13) | 34-29 | |
| » Starters: Joe Shaute vs Tommy Thomas | Fourth | 10 out |
| Tuesday, June 22 |
| » Defeated Indians (35-29), 4-3 | Comiskey Park I (17-13) | 35-29 | |
| » Starters: Sherry Smith vs Ted Lyons | Second | 9½ out |
| Wednesday, June 23 |
| » Defeated Indians (35-30), 5-3 | Comiskey Park I (18-13) | 36-29 | Won 2 |
| » Starters: George Uhle vs Ted Blankenship | Second | 9 out |
| Thursday, June 24 |
| » Defeated Indians (35-31), 9-6 | Comiskey Park I (19-13) | 37-29 | Won 3 |
| » Starters: Garland Buckeye vs Jim Joe Edwards | Second | 8 out |
| Friday, June 25 |
| » Lost to Browns (26-39), 11-4 | Comiskey Park I (19-14) | 37-30 | |
| » Starters: Milt Gaston vs Red Faber | Second | 9½ out |
| Saturday, June 26 |
| » Lost to Browns (27-39), 5-4 | Comiskey Park I (19-15) | 37-31 | Lost 2 |
| » Starters: Tom Zachary vs Ted Lyons | Second | 9½ out |
| » Defeated Browns (27-40), 6-3 | Comiskey Park I (20-15) | 38-31 | |
| » Starters: Ernie Wingard vs Tommy Thomas | Second | 9½ out |
| Sunday, June 27 |
| » Defeated Browns (27-41), 6-3 | Comiskey Park I (21-15) | 39-31 | Won 2 |
| » Starters: Chet Falk vs Ted Blankenship | Second | 9½ out |
| Monday, June 28 |
| » Defeated Browns (27-42), 7-0 | Comiskey Park I (22-15) | 40-31 | Won 3 |
| » Starters: Elam Vangilder vs Jim Joe Edwards | Second | 8½ out |
| Tuesday, June 29 |
| » Lost to Indians (37-34), 4-2 | League Park II (6-2) | 40-32 | |
| » Starters: Milt Steengrafe vs Joe Shaute | Second | 9½ out |
| Wednesday, June 30 |
| » Lost to Indians (38-34), 11-3 | League Park II (6-3) | 40-33 | Lost 2 |
| » Starters: Ted Lyons vs Dutch Levsen | Second | 9½ out |
| Thursday, July 1 |
| » Lost to Browns (29-43), 4-3 | Sportsman's Park III (3-4) | 40-34 | Lost 3 |
| » Starters: Tommy Thomas vs Ernie Wingard | Second | 10 out |
| Friday, July 2 |
| » Lost to Browns (30-43), 3-2 | Sportsman's Park III (3-5) | 40-35 | Lost 4 |
| » Starters: Ted Blankenship vs Win Ballou | Second | 10 out |
| Saturday, July 3 |
| » Defeated Browns (30-44), 8-3 | Sportsman's Park III (4-5) | 41-35 | |
| » Starters: Jim Joe Edwards vs Milt Gaston | Second | 10 out |
| Sunday, July 4 |
| » Defeated Tigers (38-37), 7-2 | Tiger Stadium (5-2) | 42-35 | Won 2 |
| » Starters: Red Faber vs Ed Wells | Second | 9½ out |
| Monday, July 5 |
| » Lost to Indians (41-36), 4-2 | Comiskey Park I (22-16) | 42-36 | |
| » Starters: Dutch Levsen vs Ted Lyons | Third | 8½ out |
| » Defeated Indians (41-37), 8-0 | Comiskey Park I (23-16) | 43-36 | |
| » Starters: Garland Buckeye vs Tommy Thomas | Third | 8½ out |
| Tuesday, July 6 |
| » Defeated Indians (41-38), 8-0 | Comiskey Park I (24-16) | 44-36 | Won 2 |
| » Starters: Benn Karr vs Ted Blankenship | Second | 8 out |
| Thursday, July 8 |
| » Lost to Athletics (44-36), 8-7 | Shibe Park (1-4) | 44-37 | |
| » Starters: Sloppy Thurston vs Howard Ehmke | Third | 8 out |
| Friday, July 9 |
| » Lost to Athletics (45-36), 4-3 | Shibe Park (1-5) | 44-38 | Lost 2 |
| » Starters: Tommy Thomas vs Eddie Rommel | Third | 9 out |
| Saturday, July 10 |
| » Lost to Athletics (46-36), 17-14 | Shibe Park (1-6) | 44-39 | Lost 3 |
| » Starters: Ted Blankenship vs Lefty Grove | Third | 10 out |
| Monday, July 12 |
| » Defeated Athletics (46-37), 8-6 | Shibe Park (2-6) | 45-39 | |
| » Starters: Ted Lyons vs Jack Quinn | Third | 8½ out |
| Tuesday, July 13 |
| » Lost to Senators (42-37), 13-9 | Griffith Stadium (2-3) | 45-40 | |
| » Starters: Tommy Thomas vs Dutch Ruether | Fourth | 8½ out |
| Wednesday, July 14 |
| » Defeated Senators (42-38), 10-2 | Griffith Stadium (3-3) | 46-40 | |
| » Starters: Red Faber vs Stan Coveleski | Third | 8½ out |
| Saturday, July 17 |
| » Lost to Red Sox (26-59), 3-2 | Fenway Park (2-3) | 46-41 | |
| » Starters: Ted Blankenship vs Slim Harriss | Fifth | 10 out |
| » Lost to Red Sox (27-59), 4-3 | Fenway Park (2-4) | 46-42 | Lost 2 |
| » Starters: Ted Lyons vs Ted Wingfield | Fifth | 10 out |
| Monday, July 19 |
| » Defeated Red Sox (27-60), 5-4 | Fenway Park (3-4) | 47-42 | |
| » Starters: Tommy Thomas vs Fred Heimach | Third | 9½ out |
| Tuesday, July 20 |
| » Defeated Red Sox (27-61), 13-2 | Fenway Park (4-4) | 48-42 | Won 2 |
| » Starters: Red Faber vs Red Ruffing | Fourth | 8½ out |
| Wednesday, July 21 |
| » Defeated Yankees (56-34), 4-3 | Yankee Stadium (1-3) | 49-42 | Won 3 |
| » Starters: Ted Blankenship vs Waite Hoyt | Fourth | 8½ out |
| » Lost to Yankees (57-34), 5-4 | Yankee Stadium (1-4) | 49-43 | |
| » Starters: Jim Joe Edwards vs Herb Pennock | Fourth | 8½ out |
| Thursday, July 22 |
| » Lost to Yankees (58-34), 13-10 | Yankee Stadium (1-5) | 49-44 | Lost 2 |
| » Starters: Tommy Thomas vs Myles Thomas | Fourth | 9½ out |
| Friday, July 23 |
| » Lost to Yankees (59-34), 11-3 | Yankee Stadium (1-6) | 49-45 | Lost 3 |
| » Starters: Ted Lyons vs Urban Shocker | Fourth | 10½ out |
| Future White Sox Johnny Groth is born in Chicago, IL. |
| Saturday, July 24 |
| » Lost to Yankees (60-34), 7-4 | Yankee Stadium (1-7) | 49-46 | Lost 4 |
| » Starters: Red Faber vs Bob Shawkey | Fifth | 11½ out |
| Sunday, July 25 |
| » Lost to Yankees (61-34), 2-1 | Yankee Stadium (1-8) | 49-47 | Lost 5 |
| » Starters: Ted Blankenship vs Waite Hoyt | Fifth | 12½ out |
| Tuesday, July 27 |
| » Lost to Senators (47-45), 7-2 | Comiskey Park I (24-17) | 49-48 | Lost 6 |
| » Starters: Walter Johnson vs Tommy Thomas | Sixth | 13½ out |
| Wednesday, July 28 |
| » Defeated Senators (47-46), 5-2 | Comiskey Park I (25-17) | 50-48 | |
| » Starters: Dutch Ruether vs Red Faber | Fifth | 13½ out |
| Thursday, July 29 |
| » Lost to Senators (48-46), 7-3 | Comiskey Park I (25-18) | 50-49 | |
| » Starters: Alvin Crowder vs Ted Blankenship | Sixth | 14½ out |
| Friday, July 30 |
| » Defeated Senators (48-47), 5-4 | Comiskey Park I (26-18) | 51-49 | |
| » Starters: Stan Coveleski vs Sloppy Thurston | Fifth | 14½ out |
| Saturday, July 31 |
| » Lost to Yankees (66-34), 2-1 | Comiskey Park I (26-19) | 51-50 | |
| » Starters: Sam Jones vs Jim Joe Edwards | Sixth | 15½ out |
| Sunday, August 1 |
| » Lost to Yankees (67-34), 8-4 | Comiskey Park I (26-20) | 51-51 | Lost 2 |
| » Starters: Herb Pennock vs Tommy Thomas | Sixth | 16½ out |
| Monday, August 2 |
| » Defeated Yankees (67-35), 2-1 | Comiskey Park I (27-20) | 52-51 | |
| » Starters: Urban Shocker vs Red Faber | Fifth | 15½ out |
| Tuesday, August 3 |
| » Lost to Yankees (68-35), 7-6 | Comiskey Park I (27-21) | 52-52 | |
| » Starters: Walter Beall vs Sloppy Thurston | Sixth | 16½ out |
| Wednesday, August 4 |
| » Defeated Red Sox (33-70), 7-3 | Comiskey Park I (28-21) | 53-52 | |
| » Starters: Slim Harriss vs Ted Lyons | Fifth | 15½ out |
| Thursday, August 5 |
| » Defeated Red Sox (33-71), 7-2 | Comiskey Park I (29-21) | 54-52 | Won 2 |
| » Starters: Red Ruffing vs Tommy Thomas | Fifth | 15½ out |
| Friday, August 6 |
| » Defeated Red Sox (33-72), 7-4 | Comiskey Park I (30-21) | 55-52 | Won 3 |
| » Starters: Ted Wingfield vs Sarge Connally | Fourth | 15½ out |
| Saturday, August 7 |
| » Lost to Athletics (56-51), 3-2 | Comiskey Park I (30-22) | 55-53 | |
| » Starters: Howard Ehmke vs Red Faber | Fourth | 15 out |
| » Defeated Athletics (56-52), 1-0 | Comiskey Park I (31-22) | 56-53 | |
| » Starters: Eddie Rommel vs Jim Joe Edwards | Fourth | 15 out |
| Sunday, August 8 |
| » Lost to Athletics (57-52), 6-5 | Comiskey Park I (31-23) | 56-54 | |
| » Starters: Jack Quinn vs Sloppy Thurston | Fifth | 15 out |
| Monday, August 9 |
| » Lost to Athletics (58-52), 2-1 | Comiskey Park I (31-24) | 56-55 | Lost 2 |
| » Starters: Rube Walberg vs Ted Lyons | Fifth | 16 out |
| Tuesday, August 10 |
| » Lost to Athletics (59-52), 4-3 | Comiskey Park I (31-25) | 56-56 | Lost 3 |
| » Starters: Lefty Grove vs Tommy Thomas | Sixth | 16 out |
| Wednesday, August 11 |
| » Defeated Indians (63-51), 7-2 | League Park II (7-3) | 57-56 | |
| » Starters: Jim Joe Edwards vs Joe Shaute | Sixth | 14½ out |
| Thursday, August 12 |
| » Lost to Indians (64-51), 5-0 | League Park II (7-4) | 57-57 | |
| » Starters: Red Faber vs Jake Miller | Sixth | 14½ out |
| Saturday, August 14 |
| » Lost to Tigers (60-56), 5-2 | Comiskey Park I (31-26) | 57-58 | Lost 2 |
| » Starters: Earl Whitehill vs Tommy Thomas | Sixth | 15½ out |
| Sunday, August 15 |
| » Tied Tigers, 0-0 | Comiskey Park I (31-26) | 57-58 | |
| » Starters: Rip Collins vs Jim Joe Edwards | Sixth | 15½ out |
| Monday, August 16 |
| » Tied Tigers, 0-0 | Tiger Stadium (5-2) | 57-58 | |
| » Starters: Ted Lyons vs Sam Gibson | Sixth | 15½ out |
| Tuesday, August 17 |
| » Defeated Yankees (74-45), 5-3 | Yankee Stadium (2-8) | 58-58 | |
| » Starters: Sarge Connally vs Waite Hoyt | Sixth | 14½ out |
| Thursday, August 19 |
| » Lost to Red Sox (42-79), 1-0 | Fenway Park (4-5) | 58-59 | |
| » Starters: Tommy Thomas vs Ted Wingfield | Fifth | 15 out |
| Friday, August 20 |
| » Defeated Red Sox (42-80), 5-1 | Fenway Park (5-5) | 59-59 | |
| » Starters: Red Faber vs Paul Zahniser | Sixth | 15 out |
| Saturday, August 21 |
| » Defeated Red Sox (42-81), 6-0 | Fenway Park (6-5) | 60-59 | Won 2 |
| » Starters: Ted Lyons vs Slim Harriss | Sixth | 15 out |
| Sunday, August 22 |
| » Lost to Athletics (66-56), 3-2 | Shibe Park (2-7) | 60-60 | |
| » Starters: Jim Joe Edwards vs Lefty Grove | Sixth | 15½ out |
| Monday, August 23 |
| » Lost to Athletics (67-56), 4-1 | Shibe Park (2-8) | 60-61 | Lost 2 |
| » Starters: Tommy Thomas vs Howard Ehmke | Sixth | 16½ out |
| Thursday, August 26 |
| » Lost to Senators (61-59), 9-3 | Griffith Stadium (3-4) | 60-62 | Lost 3 |
| » Starters: Red Faber vs Walter Johnson | Sixth | 17 out |
| » Lost to Senators (62-59), 1-0 | Griffith Stadium (3-5) | 60-63 | Lost 4 |
| » Starters: Ted Lyons vs Stan Coveleski | Sixth | 17 out |
| Friday, August 27 |
| » Defeated Senators (62-60), 5-3 | Griffith Stadium (4-5) | 61-63 | |
| » Starters: Sarge Connally vs Firpo Marberry | Sixth | 17 out |
| Saturday, August 28 |
| » Lost to Senators (63-60), 3-2 | Griffith Stadium (4-6) | 61-64 | |
| » Starters: Jim Joe Edwards vs George Murray | Sixth | 17 out |
| Sunday, August 29 |
| » Lost to Senators (64-60), 9-2 | Griffith Stadium (4-7) | 61-65 | Lost 2 |
| » Starters: Tommy Thomas vs Alvin Crowder | Sixth | 18 out |
| Monday, August 30 |
| » Defeated Tigers (66-60), 5-2 | Tiger Stadium (6-2) | 62-65 | |
| » Starters: Ted Lyons vs Sam Gibson | Sixth | 17 out |
| Tuesday, August 31 |
| » Defeated Tigers (66-61), 19-2 | Tiger Stadium (7-2) | 63-65 | Won 2 |
| » Starters: Red Faber vs Earl Whitehill | Sixth | 16½ out |
| » Lost to Tigers (67-61), 7-6 | Tiger Stadium (7-3) | 63-66 | |
| » Starters: Sarge Connally vs Ed Wells | Sixth | 16½ out |
| Wednesday, September 1 |
| » Defeated Tigers (67-62), 11-7 | Tiger Stadium (8-3) | 64-66 | |
| » Starters: Jim Joe Edwards vs Lil Stoner | Sixth | 16½ out |
| Saturday, September 4 |
| » Lost to Browns (53-78), 5-3 | Sportsman's Park III (4-6) | 64-67 | |
| » Starters: Jim Joe Edwards vs Tom Zachary | Sixth | 17½ out |
| Sunday, September 5 |
| » Defeated Browns (53-79), 9-8 | Sportsman's Park III (5-6) | 65-67 | |
| » Starters: Tommy Thomas vs Win Ballou | Sixth | 17 out |
| Monday, September 6 |
| » Defeated Tigers (69-65), 5-4 | Comiskey Park I (32-26) | 66-67 | Won 2 |
| » Starters: Lil Stoner vs Red Faber | Sixth | 16 out |
| » Defeated Tigers (69-66), 7-5 | Comiskey Park I (33-26) | 67-67 | Won 3 |
| » Starters: Rip Collins vs Sloppy Thurston | Sixth | 16 out |
| Tuesday, September 7 |
| » Defeated Tigers (69-67), 4-2 | Comiskey Park I (34-26) | 68-67 | Won 4 |
| » Starters: George Smith vs Jim Joe Edwards | Sixth | 16 out |
| » Major-league debuts: Pid Purdy (White Sox) |
| Thursday, September 9 |
| » Defeated Browns (55-81), 3-1 | Comiskey Park I (35-26) | 69-67 | Won 5 |
| » Starters: Milt Gaston vs Tommy Thomas | Sixth | 15 out |
| » Defeated Browns (55-82), 5-1 | Comiskey Park I (36-26) | 70-67 | Won 6 |
| » Starters: Tom Zachary vs Sarge Connally | Sixth | 15 out |
| Friday, September 10 |
| » Lost to Browns (56-82), 5-4 | Comiskey Park I (36-27) | 70-68 | |
| » Starters: Win Ballou vs Ted Lyons | Sixth | 15½ out |
| Saturday, September 11 |
| » Lost to Athletics (74-61), 11-5 | Comiskey Park I (36-28) | 70-69 | Lost 2 |
| » Starters: Lefty Grove vs Jim Joe Edwards | Sixth | 16½ out |
| Monday, September 13 |
| » Lost to Athletics (75-61), 5-2 | Comiskey Park I (36-29) | 70-70 | Lost 3 |
| » Starters: Howard Ehmke vs Sarge Connally | Sixth | 15½ out |
| » Defeated Athletics (75-62), 3-2 | Comiskey Park I (37-29) | 71-70 | |
| » Starters: Eddie Rommel vs Red Faber | Sixth | 15½ out |
| Wednesday, September 15 |
| » Defeated Red Sox (45-99), 5-1 | Comiskey Park I (38-29) | 72-70 | Won 2 |
| » Starters: Ted Wingfield vs Tommy Thomas | Sixth | 15½ out |
| Thursday, September 16 |
| » Defeated Red Sox (45-100), 6-4 | Comiskey Park I (39-29) | 73-70 | Won 3 |
| » Starters: Slim Harriss vs Ted Blankenship | Sixth | 14 out |
| Friday, September 17 |
| » Defeated Red Sox (45-101), 3-2 | Comiskey Park I (40-29) | 74-70 | Won 4 |
| » Starters: Red Ruffing vs Ted Lyons | Fifth | 13 out |
| Saturday, September 18 |
| » Defeated Red Sox (45-102), 6-3 | Comiskey Park I (41-29) | 75-70 | Won 5 |
| » Starters: Hal Wiltse vs Sarge Connally | Fifth | 12 out |
| Sunday, September 19 |
| » Defeated Red Sox (45-103), 6-3 | Comiskey Park I (42-29) | 76-70 | Won 6 |
| » Starters: Paul Zahniser vs Tommy Thomas | Fifth | 12 out |
| Monday, September 20 |
| » Defeated Yankees (88-59), 7-3 | Comiskey Park I (43-29) | 77-70 | Won 7 |
| » Starters: Herb Pennock vs Red Faber | Fifth | 10 out |
| » Defeated Yankees (88-60), 4-3 | Comiskey Park I (44-29) | 78-70 | Won 8 |
| » Starters: Sam Jones vs Ted Blankenship | Fifth | 10 out |
| Tuesday, September 21 |
| » Lost to Yankees (89-60), 14-0 | Comiskey Park I (44-30) | 78-71 | |
| » Starters: Waite Hoyt vs Ted Lyons | Fifth | 11 out |
| Wednesday, September 22 |
| » Defeated Yankees (89-61), 2-1 | Comiskey Park I (45-30) | 79-71 | |
| » Starters: Urban Shocker vs Sloppy Thurston | Fifth | 10 out |
| Saturday, September 25 |
| » Defeated Senators (80-68), 2-1 | Comiskey Park I (46-30) | 80-71 | Won 2 |
| » Starters: Walter Johnson vs Tommy Thomas | Fifth | 11 out |
| » Lost to Senators (81-68), 3-2 | Comiskey Park I (46-31) | 80-72 | |
| » Starters: Stan Coveleski vs Ted Blankenship | Fifth | 11 out |
| Sunday, September 26 |
| » Defeated Senators (81-69), 7-4 | Comiskey Park I (47-31) | 81-72 | |
| » Starters: Dick Jones vs Sarge Connally | Fifth | 9½ out |
| Friday, November 12 |
| Future White Sox Don Johnson is born in Portland, OR. |
| Thursday, November 18 |
| Future White Sox Roy Sievers is born in St. Louis, MO. |
Game information provided by Retrosheet (www.retrosheet.org) |