| Wednesday, April 2 |
| Future Red Sox Bobby Avila is born in Veracruz, Mexico. |
| Tuesday, April 15 |
| » Lost to Yankees (1-0), 2-1 | Fenway Park (0-1) | 0-1 | |
| » Starters: Bob Shawkey vs Howard Ehmke | Second | 1 out |
| Wednesday, April 16 |
| » Defeated Yankees (1-1), 9-6 | Fenway Park (1-1) | 1-1 | |
| » Starters: Sam Jones vs Jack Quinn | Second | 1 out |
| » Major-league debuts: Earle Combs (Yankees) |
| Thursday, April 17 |
| » Defeated Yankees (1-2), 9-1 | Fenway Park (2-1) | 2-1 | Won 2 |
| » Starters: Waite Hoyt vs Alex Ferguson | Second | ½ out |
| Saturday, April 19 |
| » Defeated Athletics (2-2), 12-0 | Fenway Park (3-1) | 3-1 | Won 3 |
| » Starters: Bob Hasty vs Howard Ehmke | First | -- |
| Monday, April 21 |
| » Lost to Athletics (3-2), 4-0 | Fenway Park (3-2) | 3-2 | |
| » Starters: Eddie Rommel vs Jack Quinn | Second | 1 out |
| Wednesday, April 23 |
| » Lost to Yankees (4-4), 13-4 | Yankee Stadium (0-1) | 3-3 | Lost 2 |
| » Starters: Howard Ehmke vs Herb Pennock | Fourth | 1½ out |
| Thursday, April 24 |
| » Lost to Yankees (5-4), 6-3 | Yankee Stadium (0-2) | 3-4 | Lost 3 |
| » Starters: Alex Ferguson vs Bob Shawkey | Sixth | 2½ out |
| Friday, April 25 |
| » Lost to Yankees (6-4), 5-2 | Yankee Stadium (0-3) | 3-5 | Lost 4 |
| » Starters: Bill Piercy vs Joe Bush | Sixth | 2½ out |
| » Major-league debuts: Phil Todt (Red Sox) |
| Saturday, April 26 |
| » Lost to Yankees (7-4), 4-3 | Yankee Stadium (0-4) | 3-6 | Lost 5 |
| » Starters: Jack Quinn vs Waite Hoyt | Seventh | 3½ out |
| Sunday, April 27 |
| » Lost to Senators (5-7), 9-6 | Griffith Stadium (0-1) | 3-7 | Lost 6 |
| » Starters: Howard Ehmke vs Tom Zachary | Seventh | 4½ out |
| Monday, April 28 |
| » Tied Senators, 2-2 | Griffith Stadium (0-1) | 3-7 | |
| » Starters: Alex Ferguson vs Firpo Marberry | Eighth | 5 out |
| Tuesday, April 29 |
| » Defeated Senators (5-8), 15-6 | Griffith Stadium (1-1) | 4-7 | |
| » Starters: Bill Piercy vs Joe Martina | Sixth | 4 out |
| » Major-league debuts: Bennie Tate (Senators) |
| Thursday, May 1 |
| » Defeated Athletics (6-6), 5-1 | Shibe Park (1-0) | 5-7 | Won 2 |
| » Starters: Jack Quinn vs Eddie Rommel | Fifth | 3 out |
| Friday, May 2 |
| » Defeated Athletics (6-7), 11-0 | Shibe Park (2-0) | 6-7 | Won 3 |
| » Starters: Howard Ehmke vs Rollie Naylor | Third | 2 out |
| Saturday, May 3 |
| » Defeated Athletics (6-8), 9-6 | Shibe Park (3-0) | 7-7 | Won 4 |
| » Starters: Bill Piercy vs Curly Ogden | Fourth | 2 out |
| Monday, May 5 |
| » Defeated Senators (8-10), 8-3 | Fenway Park (4-2) | 8-7 | Won 5 |
| » Starters: Tom Zachary vs Alex Ferguson | Third | 2 out |
| Tuesday, May 6 |
| » Defeated Senators (8-11), 14-4 | Fenway Park (5-2) | 9-7 | Won 6 |
| » Starters: Paul Zahniser vs Oscar Fuhr | Third | 2 out |
| Wednesday, May 7 |
| » Lost to Senators (9-11), 5-4 | Fenway Park (5-3) | 9-8 | |
| » Starters: George Mogridge vs Jack Quinn | Third | 3 out |
| Thursday, May 8 |
| » Defeated Senators (9-12), 4-2 | Fenway Park (6-3) | 10-8 | |
| » Starters: Walter Johnson vs Howard Ehmke | Third | 2½ out |
| Tuesday, May 13 |
| » Lost to Browns (12-10), 5-3 | Fenway Park (6-4) | 10-9 | |
| » Starters: Dave Danforth vs Howard Ehmke | Third | 3 out |
| Wednesday, May 14 |
| » Defeated White Sox (10-11), 12-0 | Fenway Park (7-4) | 11-9 | |
| » Starters: Sarge Connally vs Jack Quinn | Third | 2 out |
| Thursday, May 15 |
| » Lost to White Sox (11-11), 4-2 | Fenway Park (7-5) | 11-10 | |
| » Starters: Sloppy Thurston vs Oscar Fuhr | Third | 2 out |
| Friday, May 16 |
| » Defeated White Sox (11-12), 4-3 | Fenway Park (8-5) | 12-10 | |
| » Starters: Dixie Leverett vs Alex Ferguson | Third | 1½ out |
| Saturday, May 17 |
| » Defeated White Sox (11-13), 5-4 | Fenway Park (9-5) | 13-10 | Won 2 |
| » Starters: Ted Lyons vs Bill Piercy | Second | 1½ out |
| Sunday, May 18 |
| » Defeated Tigers (14-12), 5-4 | Tiger Stadium (1-0) | 14-10 | Won 3 |
| » Starters: Oscar Fuhr vs Bert Cole | Second | 1½ out |
| Monday, May 19 |
| » Defeated Tigers (14-13), 9-1 | Fenway Park (10-5) | 15-10 | Won 4 |
| » Starters: Ken Holloway vs Howard Ehmke | Second | 1 out |
| Wednesday, May 21 |
| » Defeated Tigers (14-14), 5-4 | Fenway Park (11-5) | 16-10 | Won 5 |
| » Starters: Rip Collins vs Jack Quinn | Second | ½ out |
| Thursday, May 22 |
| » Lost to Tigers (15-14), 6-5 | Fenway Park (11-6) | 16-11 | |
| » Starters: Lil Stoner vs Oscar Fuhr | Second | 1½ out |
| Friday, May 23 |
| » Defeated Indians (12-15), 5-1 | Fenway Park (12-6) | 17-11 | |
| » Starters: George Uhle vs Howard Ehmke | Second | 1½ out |
| Saturday, May 24 |
| » Defeated Indians (12-16), 6-2 | Fenway Park (13-6) | 18-11 | Won 2 |
| » Starters: Stan Coveleski vs Alex Ferguson | Second | ½ out |
| Monday, May 26 |
| » Defeated Indians (12-17), 10-9 | Fenway Park (14-6) | 19-11 | Won 3 |
| » Starters: George Edmondson vs Oscar Fuhr | First | -- |
| Tuesday, May 27 |
| Future Red Sox Tom Hurd is born in Danville, VA. |
| Wednesday, May 28 |
| » Lost to Athletics (12-19), 2-1 | Shibe Park (3-1) | 19-12 | |
| » Starters: Howard Ehmke vs Dennis Burns | First | -- |
| » Defeated Athletics (12-20), 1-0 | Shibe Park (4-1) | 20-12 | |
| » Starters: Jack Quinn vs Roy Meeker | First | -- |
| Friday, May 30 |
| » Defeated Senators (15-19), 9-4 | Fenway Park (15-6) | 21-12 | Won 2 |
| » Starters: Joe Martina vs Alex Ferguson | First | -- |
| » Lost to Senators (16-19), 10-5 | Fenway Park (15-7) | 21-13 | |
| » Starters: Walter Johnson vs Oscar Fuhr | First | -- |
| Saturday, May 31 |
| » Lost to Senators (17-19), 12-0 | Fenway Park (15-8) | 21-14 | Lost 2 |
| » Starters: Curly Ogden vs George Murray | Second | ½ out |
| » Major-league debuts: Red Ruffing (Red Sox) |
| Tuesday, June 3 |
| » Defeated Browns (18-21), 8-7 | Sportsman's Park III (1-0) | 22-14 | |
| » Starters: Jack Quinn vs Urban Shocker | Second | ½ out |
| Wednesday, June 4 |
| » Defeated Browns (18-22), 6-5 | Sportsman's Park III (2-0) | 23-14 | Won 2 |
| » Starters: Bill Piercy vs Dave Danforth | First | -- |
| Thursday, June 5 |
| » Lost to Browns (19-22), 5-2 | Sportsman's Park III (2-1) | 23-15 | |
| » Starters: Howard Ehmke vs Ernie Wingard | First | -- |
| Friday, June 6 |
| » Lost to Browns (20-22), 11-4 | Sportsman's Park III (2-2) | 23-16 | Lost 2 |
| » Starters: Alex Ferguson vs George Lyons | Second | 1 out |
| Saturday, June 7 |
| » Defeated White Sox (18-22), 3-1 | Comiskey Park I (1-0) | 24-16 | |
| » Starters: Jack Quinn vs Dixie Leverett | First | -- |
| Sunday, June 8 |
| » Lost to White Sox (19-22), 10-3 | Comiskey Park I (1-1) | 24-17 | |
| » Starters: Alex Ferguson vs Sloppy Thurston | First | -- |
| Monday, June 9 |
| » Defeated White Sox (19-23), 5-1 | Comiskey Park I (2-1) | 25-17 | |
| » Starters: Howard Ehmke vs Ted Lyons | First | -- |
| Tuesday, June 10 |
| » Lost to White Sox (20-23), 3-2 | Comiskey Park I (2-2) | 25-18 | |
| » Starters: Bill Piercy vs Mike Cvengros | First | -- |
| Wednesday, June 11 |
| » Lost to Indians (20-24), 5-4 | League Park II (0-1) | 25-19 | Lost 2 |
| » Starters: Jack Quinn vs Joe Shaute | First | -- |
| Thursday, June 12 |
| » Defeated Indians (20-25), 4-3 | League Park II (1-1) | 26-19 | |
| » Starters: Alex Ferguson vs Stan Coveleski | First | -- |
| Friday, June 13 |
| » Defeated Indians (20-26), 8-3 | League Park II (2-1) | 27-19 | Won 2 |
| » Starters: Howard Ehmke vs George Uhle | First | -- |
| Saturday, June 14 |
| » Lost to Indians (21-26), 3-2 | League Park II (2-2) | 27-20 | |
| » Starters: Bill Piercy vs Sherry Smith | Second | 1 out |
| Sunday, June 15 |
| » Lost to Tigers (29-25), 10-4 | Tiger Stadium (1-1) | 27-21 | Lost 2 |
| » Starters: Jack Quinn vs Earl Whitehill | Second | 1 out |
| » Major-league debuts: Buster Ross (Red Sox) |
| Monday, June 16 |
| » Lost to Tigers (30-25), 3-0 | Tiger Stadium (1-2) | 27-22 | Lost 3 |
| » Starters: Alex Ferguson vs Lil Stoner | Second | 1 out |
| Tuesday, June 17 |
| » Lost to Tigers (31-25), 7-4 | Tiger Stadium (1-3) | 27-23 | Lost 4 |
| » Starters: Howard Ehmke vs Hooks Dauss | Third | 2 out |
| Wednesday, June 18 |
| » Lost to Tigers (32-25), 5-3 | Tiger Stadium (1-4) | 27-24 | Lost 5 |
| » Starters: Bill Piercy vs Rip Collins | Third | 2 out |
| Saturday, June 21 |
| » Lost to Yankees (30-22), 5-3 | Yankee Stadium (0-5) | 27-25 | Lost 6 |
| » Starters: Jack Quinn vs Bob Shawkey | Fourth | 3 out |
| » Tied Yankees, 3-3 | Yankee Stadium (0-5) | 27-25 | |
| » Starters: Alex Ferguson vs Herb Pennock | Fourth | 3 out |
| Sunday, June 22 |
| » Defeated Yankees (30-23), 6-2 | Yankee Stadium (1-5) | 28-25 | |
| » Starters: Howard Ehmke vs Joe Bush | Third | 2 out |
| Monday, June 23 |
| » Lost to Athletics (20-35), 2-0 | Fenway Park (15-9) | 28-26 | |
| » Starters: Slim Harriss vs George Murray | Fourth | 3½ out |
| » Lost to Athletics (21-35), 6-3 | Fenway Park (15-10) | 28-27 | Lost 2 |
| » Starters: Fred Heimach vs Red Ruffing | Fourth | 3½ out |
| Tuesday, June 24 |
| » Defeated Athletics (21-36), 4-1 | Fenway Park (16-10) | 29-27 | |
| » Starters: Rollie Naylor vs Alex Ferguson | Fourth | 2 out |
| Wednesday, June 25 |
| » Defeated Athletics (21-37), 4-3 | Fenway Park (17-10) | 30-27 | Won 2 |
| » Starters: Dennis Burns vs Jack Quinn | Third | 2 out |
| Thursday, June 26 |
| » Defeated Yankees (30-28), 8-5 | Fenway Park (18-10) | 31-27 | Won 3 |
| » Starters: Cliff Markle vs Howard Ehmke | Third | 1½ out |
| Friday, June 27 |
| » Lost to Yankees (31-28), 12-7 | Fenway Park (18-11) | 31-28 | |
| » Starters: Bob Shawkey vs George Murray | Fourth | 2½ out |
| » Lost to Yankees (32-28), 10-5 | Fenway Park (18-12) | 31-29 | Lost 2 |
| » Starters: Waite Hoyt vs Buster Ross | Fourth | 2½ out |
| Saturday, June 28 |
| » Lost to Yankees (33-28), 4-3 | Fenway Park (18-13) | 31-30 | Lost 3 |
| » Starters: Herb Pennock vs Alex Ferguson | Fourth | 4 out |
| Sunday, June 29 |
| » Lost to Senators (37-27), 6-2 | Griffith Stadium (1-2) | 31-31 | Lost 4 |
| » Starters: Jack Quinn vs Tom Zachary | Fourth | 5 out |
| Monday, June 30 |
| » Defeated Senators (37-28), 2-1 | Griffith Stadium (2-2) | 32-31 | |
| » Starters: Howard Ehmke vs Walter Johnson | Fifth | 5 out |
| » Lost to Senators (38-28), 3-1 | Griffith Stadium (2-3) | 32-32 | |
| » Starters: Curt Fullerton vs Firpo Marberry | Fifth | 5 out |
| Tuesday, July 1 |
| » Lost to Senators (39-28), 2-1 | Griffith Stadium (2-4) | 32-33 | Lost 2 |
| » Starters: Bill Piercy vs Joe Martina | Sixth | 7 out |
| » Lost to Senators (40-28), 5-0 | Griffith Stadium (2-5) | 32-34 | Lost 3 |
| » Starters: Jack Quinn vs Curly Ogden | Sixth | 7 out |
| Future Red Sox Ken Wood is born in Lincolnton, NC. |
| Wednesday, July 2 |
| » Lost to Senators (41-28), 5-0 | Griffith Stadium (2-6) | 32-35 | Lost 4 |
| » Starters: Alex Ferguson vs Paul Zahniser | Seventh | 8 out |
| Friday, July 4 |
| » Lost to Athletics (26-43), 8-3 | Shibe Park (4-2) | 32-36 | Lost 5 |
| » Starters: Howard Ehmke vs Stan Baumgartner | Seventh | 8 out |
| » Lost to Athletics (27-43), 6-4 | Shibe Park (4-3) | 32-37 | Lost 6 |
| » Starters: George Murray vs Eddie Rommel | Seventh | 8 out |
| Saturday, July 5 |
| » Defeated Athletics (27-44), 6-3 | Shibe Park (5-3) | 33-37 | |
| » Starters: Bill Piercy vs Dennis Burns | Sixth | 7 out |
| » Defeated Athletics (27-45), 7-2 | Shibe Park (6-3) | 34-37 | Won 2 |
| » Starters: Curt Fullerton vs Roy Meeker | Sixth | 7 out |
| Monday, July 7 |
| » Lost to Athletics (28-45), 6-2 | Shibe Park (6-4) | 34-38 | |
| » Starters: Jack Quinn vs Slim Harriss | Seventh | 7½ out |
| » Lost to Athletics (29-45), 6-3 | Shibe Park (6-5) | 34-39 | Lost 2 |
| » Starters: Alex Ferguson vs Fred Heimach | Seventh | 7½ out |
| Tuesday, July 8 |
| » Lost to Browns (37-34), 8-7 | Fenway Park (18-14) | 34-40 | Lost 3 |
| » Starters: Urban Shocker vs Howard Ehmke | Seventh | 8 out |
| Wednesday, July 9 |
| » Defeated Browns (37-35), 5-4 | Fenway Park (19-14) | 35-40 | |
| » Starters: Elam Vangilder vs Bill Piercy | Seventh | 7 out |
| » Defeated Browns (37-36), 5-0 | Fenway Park (20-14) | 36-40 | Won 2 |
| » Starters: Dixie Davis vs Oscar Fuhr | Seventh | 7 out |
| Thursday, July 10 |
| » Defeated Browns (37-37), 8-2 | Fenway Park (21-14) | 37-40 | Won 3 |
| » Starters: Dave Danforth vs Curt Fullerton | Sixth | 6 out |
| Friday, July 11 |
| » Lost to Browns (38-37), 8-1 | Fenway Park (21-15) | 37-41 | |
| » Starters: Ernie Wingard vs Alex Ferguson | Seventh | 6½ out |
| » Defeated Browns (38-38), 7-6 | Fenway Park (22-15) | 38-41 | |
| » Starters: Ray Kolp vs Jack Quinn | Seventh | 6½ out |
| Saturday, July 12 |
| » Lost to White Sox (39-39), 17-8 | Fenway Park (22-16) | 38-42 | |
| » Starters: Sloppy Thurston vs Bill Piercy | Seventh | 7½ out |
| Monday, July 14 |
| » Lost to White Sox (40-39), 6-2 | Fenway Park (22-17) | 38-43 | Lost 2 |
| » Starters: Red Faber vs Howard Ehmke | Sixth | 8½ out |
| Tuesday, July 15 |
| » Lost to White Sox (41-39), 8-6 | Fenway Park (22-18) | 38-44 | Lost 3 |
| » Starters: Dixie Leverett vs Oscar Fuhr | Sixth | 9½ out |
| Wednesday, July 16 |
| » Lost to Tigers (46-38), 5-4 | Fenway Park (22-19) | 38-45 | Lost 4 |
| » Starters: Earl Whitehill vs Alex Ferguson | Seventh | 10 out |
| » Lost to Tigers (47-38), 11-3 | Fenway Park (22-20) | 38-46 | Lost 5 |
| » Starters: Lil Stoner vs Bill Piercy | Seventh | 10 out |
| Friday, July 18 |
| » Lost to Tigers (48-38), 4-3 | Fenway Park (22-21) | 38-47 | Lost 6 |
| » Starters: Ed Wells vs Curt Fullerton | Sixth | 10½ out |
| Saturday, July 19 |
| » Lost to Tigers (49-38), 18-1 | Fenway Park (22-22) | 38-48 | Lost 7 |
| » Starters: Rip Collins vs Oscar Fuhr | Seventh | 12 out |
| » Lost to Tigers (50-38), 4-3 | Fenway Park (22-23) | 38-49 | Lost 8 |
| » Starters: Lil Stoner vs Jack Quinn | Seventh | 12 out |
| Monday, July 21 |
| » Lost to Indians (41-48), 2-1 | Fenway Park (22-24) | 38-50 | Lost 9 |
| » Starters: George Uhle vs Howard Ehmke | Sixth | 13 out |
| Tuesday, July 22 |
| » Defeated Indians (41-49), 4-3 | Fenway Park (23-24) | 39-50 | |
| » Starters: Sherry Smith vs Curt Fullerton | Seventh | 12½ out |
| Wednesday, July 23 |
| » Defeated Indians (41-50), 16-12 | Fenway Park (24-24) | 40-50 | Won 2 |
| » Starters: Stan Coveleski vs Oscar Fuhr | Seventh | 12 out |
| Thursday, July 24 |
| » Defeated Indians (41-51), 10-9 | Fenway Park (25-24) | 41-50 | Won 3 |
| » Starters: Joe Shaute vs Bill Piercy | Fifth | 11½ out |
| Saturday, July 26 |
| » Defeated Browns (45-46), 4-2 | Sportsman's Park III (3-2) | 42-50 | Won 4 |
| » Starters: Howard Ehmke vs Ernie Wingard | Sixth | 11½ out |
| Sunday, July 27 |
| » Lost to Browns (46-46), 9-6 | Sportsman's Park III (3-3) | 42-51 | |
| » Starters: Curt Fullerton vs Dave Danforth | Fifth | 11½ out |
| Monday, July 28 |
| » Defeated Browns (46-47), 10-5 | Sportsman's Park III (4-3) | 43-51 | |
| » Starters: Bill Piercy vs Urban Shocker | Sixth | 11½ out |
| Tuesday, July 29 |
| » Lost to Browns (47-47), 3-0 | Sportsman's Park III (4-4) | 43-52 | |
| » Starters: George Murray vs Dixie Davis | Seventh | 12½ out |
| Wednesday, July 30 |
| » Lost to White Sox (46-51), 7-6 | Comiskey Park I (2-3) | 43-53 | Lost 2 |
| » Starters: Howard Ehmke vs Sarge Connally | Seventh | 13 out |
| Thursday, July 31 |
| » Lost to White Sox (47-51), 5-4 | Comiskey Park I (2-4) | 43-54 | Lost 3 |
| » Starters: Curt Fullerton vs Leo Mangum | Seventh | 12½ out |
| Friday, August 1 |
| » Lost to White Sox (48-51), 2-1 | Comiskey Park I (2-5) | 43-55 | Lost 4 |
| » Starters: Alex Ferguson vs Red Faber | Seventh | 13½ out |
| Saturday, August 2 |
| » Defeated White Sox (48-52), 7-3 | Comiskey Park I (3-5) | 44-55 | |
| » Starters: George Murray vs Charlie Robertson | Seventh | 12½ out |
| Sunday, August 3 |
| » Lost to Indians (47-55), 3-2 | League Park II (2-3) | 44-56 | |
| » Starters: Howard Ehmke vs Sherry Smith | Seventh | 12½ out |
| Monday, August 4 |
| » Lost to Indians (48-55), 14-5 | League Park II (2-4) | 44-57 | Lost 2 |
| » Starters: Curt Fullerton vs Bud Messenger | Seventh | 13½ out |
| Tuesday, August 5 |
| » Lost to Indians (49-55), 1-0 | League Park II (2-5) | 44-58 | Lost 3 |
| » Starters: Alex Ferguson vs Stan Coveleski | Seventh | 14½ out |
| Wednesday, August 6 |
| » Lost to Indians (50-55), 8-5 | League Park II (2-6) | 44-59 | Lost 4 |
| » Starters: Bill Piercy vs Joe Shaute | Seventh | 14½ out |
| Thursday, August 7 |
| » Defeated Tigers (58-47), 4-2 | Tiger Stadium (2-4) | 45-59 | |
| » Starters: Curt Fullerton vs Ken Holloway | Seventh | 14½ out |
| Friday, August 8 |
| » Lost to Tigers (59-47), 14-5 | Tiger Stadium (2-5) | 45-60 | |
| » Starters: Howard Ehmke vs Rip Collins | Eighth | 14½ out |
| Saturday, August 9 |
| » Lost to Tigers (60-47), 3-2 | Tiger Stadium (2-6) | 45-61 | Lost 2 |
| » Starters: Alex Ferguson vs Lil Stoner | Eighth | 15½ out |
| Sunday, August 10 |
| » Lost to Tigers (61-47), 13-7 | Tiger Stadium (2-7) | 45-62 | Lost 3 |
| » Starters: Jack Quinn vs Earl Whitehill | Eighth | 15½ out |
| Wednesday, August 13 |
| » Defeated White Sox (51-57), 6-0 | Fenway Park (26-24) | 46-62 | |
| » Starters: Red Faber vs Howard Ehmke | Seventh | 15½ out |
| » Defeated White Sox (51-58), 4-1 | Fenway Park (27-24) | 47-62 | Won 2 |
| » Starters: Sloppy Thurston vs Curt Fullerton | Seventh | 15½ out |
| Thursday, August 14 |
| » Defeated White Sox (51-59), 4-3 | Fenway Park (28-24) | 48-62 | Won 3 |
| » Starters: Charlie Robertson vs Alex Ferguson | Seventh | 14½ out |
| Friday, August 15 |
| » Defeated White Sox (51-60), 7-6 | Fenway Park (29-24) | 49-62 | Won 4 |
| » Starters: Leo Mangum vs Bill Piercy | Seventh | 14 out |
| Saturday, August 16 |
| » Lost to Browns (59-53), 10-2 | Fenway Park (29-25) | 49-63 | |
| » Starters: Dixie Davis vs George Murray | Eighth | 15½ out |
| » Lost to Browns (60-53), 6-4 | Fenway Park (29-26) | 49-64 | Lost 2 |
| » Starters: Elam Vangilder vs Howard Ehmke | Eighth | 15½ out |
| Monday, August 18 |
| » Defeated Browns (60-54), 3-2 | Fenway Park (30-26) | 50-64 | |
| » Starters: Ernie Wingard vs Alex Ferguson | Seventh | 16 out |
| Tuesday, August 19 |
| » Defeated Browns (60-55), 11-5 | Fenway Park (31-26) | 51-64 | Won 2 |
| » Starters: Dave Danforth vs Curt Fullerton | Seventh | 15½ out |
| Wednesday, August 20 |
| » Defeated Indians (54-63), 5-4 | Fenway Park (32-26) | 52-64 | Won 3 |
| » Starters: Sherry Smith vs Howard Ehmke | Sixth | 15 out |
| Thursday, August 21 |
| » Defeated Indians (54-64), 2-1 | Fenway Park (33-26) | 53-64 | Won 4 |
| » Starters: George Uhle vs Jack Quinn | Sixth | 14½ out |
| Friday, August 22 |
| » Defeated Indians (54-65), 5-4 | Fenway Park (34-26) | 54-64 | Won 5 |
| » Starters: Stan Coveleski vs Alex Ferguson | Fifth | 13½ out |
| Saturday, August 23 |
| » Lost to Indians (55-65), 8-6 | Fenway Park (34-27) | 54-65 | |
| » Starters: Joe Shaute vs Curt Fullerton | Sixth | 14½ out |
| Monday, August 25 |
| » Defeated Tigers (66-55), 4-3 | Fenway Park (35-27) | 55-65 | |
| » Starters: Rip Collins vs Howard Ehmke | Sixth | 14 out |
| Wednesday, August 27 |
| » Lost to Tigers (67-55), 5-4 | Fenway Park (35-28) | 55-66 | |
| » Starters: Syl Johnson vs Alex Ferguson | Sixth | 14 out |
| » Defeated Tigers (67-56), 6-3 | Fenway Park (36-28) | 56-66 | |
| » Starters: Lil Stoner vs Jack Quinn | Sixth | 14 out |
| Thursday, August 28 |
| » Defeated Athletics (56-69), 6-3 | Fenway Park (37-28) | 57-66 | Won 2 |
| » Starters: Fred Heimach vs Curt Fullerton | Fifth | 13 out |
| » Defeated Athletics (56-70), 8-7 | Fenway Park (38-28) | 58-66 | Won 3 |
| » Starters: Dennis Burns vs Clarence Winters | Fifth | 13 out |
| Friday, August 29 |
| » Defeated Athletics (56-71), 5-1 | Fenway Park (39-28) | 59-66 | Won 4 |
| » Starters: Slim Harriss vs Howard Ehmke | Fifth | 13 out |
| Saturday, August 30 |
| » Lost to Athletics (57-71), 18-7 | Fenway Park (39-29) | 59-67 | |
| » Starters: Eddie Rommel vs Clarence Winters | Sixth | 13½ out |
| » Lost to Athletics (58-71), 7-2 | Fenway Park (39-30) | 59-68 | Lost 2 |
| » Starters: Fred Heimach vs Jack Quinn | Sixth | 13½ out |
| Monday, September 1 |
| » Lost to Yankees (72-55), 3-0 | Yankee Stadium (1-6) | 59-69 | Lost 3 |
| » Starters: Curt Fullerton vs Herb Pennock | Sixth | 16 out |
| » Lost to Yankees (73-55), 12-2 | Yankee Stadium (1-7) | 59-70 | Lost 4 |
| » Starters: Bill Piercy vs Bob Shawkey | Sixth | 16 out |
| Tuesday, September 2 |
| » Defeated Yankees (73-56), 14-6 | Yankee Stadium (2-7) | 60-70 | |
| » Starters: Howard Ehmke vs Waite Hoyt | Sixth | 16 out |
| » Lost to Yankees (74-56), 5-2 | Yankee Stadium (2-8) | 60-71 | |
| » Starters: Alex Ferguson vs Joe Bush | Sixth | 16 out |
| Wednesday, September 3 |
| » Lost to Yankees (75-56), 11-6 | Yankee Stadium (2-9) | 60-72 | Lost 2 |
| » Starters: Jack Quinn vs Walter Beall | Sixth | 16½ out |
| » Major-league debuts: Walter Beall (Yankees) |
| Thursday, September 4 |
| » Lost to Senators (77-55), 12-5 | Griffith Stadium (2-7) | 60-73 | Lost 3 |
| » Starters: Curt Fullerton vs Walter Johnson | Sixth | 17½ out |
| Saturday, September 6 |
| » Lost to Senators (78-55), 8-2 | Griffith Stadium (2-8) | 60-74 | Lost 4 |
| » Starters: Howard Ehmke vs George Mogridge | Sixth | 18½ out |
| Sunday, September 7 |
| » Defeated Senators (78-56), 6-2 | Griffith Stadium (3-8) | 61-74 | |
| » Starters: Alex Ferguson vs Curly Ogden | Sixth | 17½ out |
| Monday, September 8 |
| » Lost to Yankees (77-58), 2-0 | Fenway Park (39-31) | 61-75 | |
| » Starters: Joe Bush vs Curt Fullerton | Sixth | 18½ out |
| Tuesday, September 9 |
| » Lost to Yankees (78-58), 5-4 | Fenway Park (39-32) | 61-76 | Lost 2 |
| » Starters: Herb Pennock vs Jack Quinn | Sixth | 19 out |
| Thursday, September 11 |
| » Lost to Yankees (79-58), 4-3 | Fenway Park (39-33) | 61-77 | Lost 3 |
| » Starters: Walter Beall vs Howard Ehmke | Seventh | 20½ out |
| » Lost to Yankees (80-58), 8-3 | Fenway Park (39-34) | 61-78 | Lost 4 |
| » Starters: Bob Shawkey vs Alex Ferguson | Seventh | 20½ out |
| Saturday, September 13 |
| » Lost to Browns (72-68), 6-0 | Sportsman's Park III (4-5) | 61-79 | Lost 5 |
| » Starters: Curt Fullerton vs Dixie Davis | Seventh | 21 out |
| » Defeated Browns (72-69), 13-11 | Sportsman's Park III (5-5) | 62-79 | |
| » Starters: Alex Ferguson vs George Lyons | Seventh | 21 out |
| Sunday, September 14 |
| » Defeated Browns (72-70), 10-0 | Sportsman's Park III (6-5) | 63-79 | Won 2 |
| » Starters: Buster Ross vs Ernie Wingard | Sixth | 20 out |
| Monday, September 15 |
| » Lost to Browns (73-70), 4-3 | Sportsman's Park III (6-6) | 63-80 | |
| » Starters: Ted Wingfield vs Elam Vangilder | Sixth | 20 out |
| Tuesday, September 16 |
| » Lost to White Sox (61-80), 8-4 | Comiskey Park I (3-6) | 63-81 | Lost 2 |
| » Starters: Howard Ehmke vs Ted Blankenship | Seventh | 21 out |
| Wednesday, September 17 |
| » Lost to White Sox (62-80), 3-2 | Comiskey Park I (3-7) | 63-82 | Lost 3 |
| » Starters: Alex Ferguson vs Charlie Robertson | Seventh | 22 out |
| Thursday, September 18 |
| » Lost to White Sox (63-80), 7-3 | Comiskey Park I (3-8) | 63-83 | Lost 4 |
| » Starters: Curt Fullerton vs Ted Lyons | Seventh | 23 out |
| Friday, September 19 |
| » Defeated Indians (66-81), 5-3 | League Park II (3-6) | 64-83 | |
| » Starters: Ted Wingfield vs Carl Yowell | Eighth | 23 out |
| » Major-league debuts: Freddy Spurgeon (Indians) |
| Sunday, September 21 |
| » Defeated Indians (66-82), 2-0 | League Park II (4-6) | 65-83 | Won 2 |
| » Starters: Howard Ehmke vs Jake Miller | Sixth | 22 out |
| » Defeated Indians (66-83), 11-5 | League Park II (5-6) | 66-83 | Won 3 |
| » Starters: Red Ruffing vs Luther Roy | Sixth | 22 out |
| Monday, September 22 |
| » Lost to Tigers (83-67), 9-1 | Tiger Stadium (2-8) | 66-84 | |
| » Starters: Curt Fullerton vs Herman Pillette | Sixth | 23 out |
| » Major-league debuts: Charlie Gehringer (Tigers) |
| Tuesday, September 23 |
| » Lost to Tigers (84-67), 3-2 | Tiger Stadium (2-9) | 66-85 | Lost 2 |
| » Starters: Ted Wingfield vs Lil Stoner | Sixth | 24 out |
| Friday, September 26 |
| » Defeated Senators (90-61), 2-1 | Fenway Park (40-34) | 67-85 | |
| » Starters: Walter Johnson vs Alex Ferguson | Sixth | 23½ out |
| Saturday, September 27 |
| » Lost to Senators (91-61), 7-5 | Fenway Park (40-35) | 67-86 | |
| » Starters: George Mogridge vs Howard Ehmke | Sixth | 24½ out |
| Monday, September 29 |
| » Lost to Senators (92-61), 4-2 | Fenway Park (40-36) | 67-87 | Lost 2 |
| » Starters: Tom Zachary vs Curt Fullerton | Seventh | 25½ out |
| Tuesday, September 30 |
| » Defeated Senators (92-62), 13-1 | Fenway Park (41-36) | 68-87 | |
| » Starters: By Speece vs Alex Ferguson | Sixth | 24½ out |
| Tuesday, October 14 |
| Future Red Sox Bill Renna is born in Hanford, CA. |
| Thursday, December 11 |
| Future Red Sox Hal Brown is born in Greensboro, NC. |
| Thursday, December 25 |
| Former Red Sox Doc Gessler dies in Pittsburgh, PA at the age of 45. |
Game information provided by Retrosheet (www.retrosheet.org) |