| Wednesday, April 18 |
| » Defeated Red Sox (0-1), 4-1 | Yankee Stadium (1-0) | 1-0 | |
| » Starters: Howard Ehmke vs Bob Shawkey | First | -- |
| Thursday, April 19 |
| » Defeated Red Sox (0-2), 8-2 | Yankee Stadium (2-0) | 2-0 | Won 2 |
| » Starters: Alex Ferguson vs Joe Bush | First | -- |
| Friday, April 20 |
| » Defeated Red Sox (0-3), 4-3 | Yankee Stadium (3-0) | 3-0 | Won 3 |
| » Starters: Bill Piercy vs Waite Hoyt | First | -- |
| » Major-league debuts: Hinkey Haines and Harvey Hendrick (Yankees) |
| Saturday, April 21 |
| » Defeated Red Sox (0-4), 7-6 | Yankee Stadium (4-0) | 4-0 | Won 4 |
| » Starters: Lefty O'Doul vs Carl Mays | First | -- |
| Sunday, April 22 |
| » Lost to Senators (2-3), 4-3 | Yankee Stadium (4-1) | 4-1 | |
| » Starters: Walter Johnson vs Bob Shawkey | Second | 1 out |
| Monday, April 23 |
| » Lost to Senators (3-3), 2-1 | Yankee Stadium (4-2) | 4-2 | Lost 2 |
| » Starters: Cy Warmoth vs Joe Bush | Second | 2 out |
| Tuesday, April 24 |
| » Defeated Senators (3-4), 4-0 | Yankee Stadium (5-2) | 5-2 | |
| » Starters: George Mogridge vs Sam Jones | Second | 1 out |
| Wednesday, April 25 |
| » Defeated Senators (3-5), 7-1 | Yankee Stadium (6-2) | 6-2 | Won 2 |
| » Starters: Bonnie Hollingsworth vs Herb Pennock | First | -- |
| Thursday, April 26 |
| » Lost to Red Sox (3-5), 5-4 | Fenway Park (0-1) | 6-3 | |
| » Starters: Waite Hoyt vs Howard Ehmke | Second | 1 out |
| Friday, April 27 |
| » Defeated Red Sox (3-6), 4-2 | Fenway Park (1-1) | 7-3 | |
| » Starters: Bob Shawkey vs Curt Fullerton | Second | 1 out |
| Saturday, April 28 |
| » Lost to Red Sox (4-6), 5-3 | Fenway Park (1-2) | 7-4 | |
| » Starters: Joe Bush vs George Murray | Second | 1 out |
| Monday, April 30 |
| » Defeated Senators (4-7), 17-4 | Griffith Stadium (1-0) | 8-4 | |
| » Starters: Sam Jones vs Cy Warmoth | Second | 1½ out |
| Tuesday, May 1 |
| » Defeated Senators (4-8), 8-7 | Griffith Stadium (2-0) | 9-4 | Won 2 |
| » Starters: Carl Mays vs Tom Zachary | Second | ½ out |
| Wednesday, May 2 |
| » Lost to Senators (5-8), 3-0 | Griffith Stadium (2-1) | 9-5 | |
| » Starters: Bob Shawkey vs Walter Johnson | Second | ½ out |
| Thursday, May 3 |
| » Defeated Senators (5-9), 3-2 | Griffith Stadium (3-1) | 10-5 | |
| » Starters: Herb Pennock vs Cy Warmoth | Second | ½ out |
| Friday, May 4 |
| » Lost to Athletics (8-6), 8-6 | Yankee Stadium (6-3) | 10-6 | |
| » Starters: Slim Harriss vs Waite Hoyt | Second | ½ out |
| Saturday, May 5 |
| » Defeated Athletics (8-7), 7-2 | Yankee Stadium (7-3) | 11-6 | |
| » Starters: Fred Heimach vs Joe Bush | First | -- |
| Sunday, May 6 |
| » Lost to Athletics (9-7), 5-1 | Yankee Stadium (7-4) | 11-7 | |
| » Starters: Eddie Rommel vs Sam Jones | First | -- |
| Tuesday, May 8 |
| » Defeated Indians (12-9), 3-2 | League Park II (1-0) | 12-7 | |
| » Starters: Bob Shawkey vs Stan Coveleski | First | -- |
| Thursday, May 10 |
| » Defeated Indians (12-10), 13-4 | League Park II (2-0) | 13-7 | Won 2 |
| » Starters: Herb Pennock vs Jim Joe Edwards | First | -- |
| Saturday, May 12 |
| » Defeated Tigers (12-11), 3-2 | Tiger Stadium (1-0) | 14-7 | Won 3 |
| » Starters: Joe Bush vs Herman Pillette | First | -- |
| Sunday, May 13 |
| » Lost to Tigers (13-11), 4-1 | Tiger Stadium (1-1) | 14-8 | |
| » Starters: Sam Jones vs Hooks Dauss | First | -- |
| Monday, May 14 |
| » Defeated Tigers (13-12), 16-11 | Tiger Stadium (2-1) | 15-8 | |
| » Starters: Bob Shawkey vs Ken Holloway | First | -- |
| Tuesday, May 15 |
| » Defeated Tigers (13-13), 9-5 | Tiger Stadium (3-1) | 16-8 | Won 2 |
| » Starters: Herb Pennock vs Rip Collins | First | -- |
| Wednesday, May 16 |
| » Defeated Browns (11-13), 4-1 | Sportsman's Park III (1-0) | 17-8 | Won 3 |
| » Starters: Waite Hoyt vs Elam Vangilder | First | -- |
| Thursday, May 17 |
| » Defeated Browns (11-14), 9-2 | Sportsman's Park III (2-0) | 18-8 | Won 4 |
| » Starters: Joe Bush vs Urban Shocker | First | -- |
| Friday, May 18 |
| » Defeated Browns (11-15), 9-4 | Sportsman's Park III (3-0) | 19-8 | Won 5 |
| » Starters: Bob Shawkey vs Dave Danforth | First | -- |
| » Major-league debuts: Benny Bengough (Yankees) |
| Saturday, May 19 |
| » Defeated Browns (11-16), 6-5 | Sportsman's Park III (4-0) | 20-8 | Won 6 |
| » Starters: Carl Mays vs Hub Pruett | First | -- |
| Sunday, May 20 |
| » Defeated White Sox (10-16), 3-2 | Comiskey Park I (1-0) | 21-8 | Won 7 |
| » Starters: Sam Jones vs Red Faber | First | -- |
| Monday, May 21 |
| » Defeated White Sox (10-17), 5-0 | Comiskey Park I (2-0) | 22-8 | Won 8 |
| » Starters: Waite Hoyt vs Sloppy Thurston | First | -- |
| Tuesday, May 22 |
| » Defeated White Sox (10-18), 3-1 | Comiskey Park I (3-0) | 23-8 | Won 9 |
| » Starters: Herb Pennock vs Mike Cvengros | First | -- |
| Thursday, May 24 |
| » Lost to Athletics (18-12), 1-0 | Shibe Park (0-1) | 23-9 | |
| » Starters: Joe Bush vs Eddie Rommel | First | -- |
| Friday, May 25 |
| » Lost to Athletics (19-12), 4-2 | Shibe Park (0-2) | 23-10 | Lost 2 |
| » Starters: Bob Shawkey vs Rollie Naylor | First | -- |
| Saturday, May 26 |
| » Defeated Athletics (19-13), 10-8 | Shibe Park (1-2) | 24-10 | |
| » Starters: Carl Mays vs Bob Hasty | First | -- |
| Sunday, May 27 |
| » Defeated Senators (14-18), 8-1 | Griffith Stadium (4-1) | 25-10 | Won 2 |
| » Starters: Sam Jones vs Cy Warmoth | First | -- |
| Monday, May 28 |
| Future Yankee Bob Kuzava is born in Wyandotte, MI. |
| Tuesday, May 29 |
| » Defeated Senators (14-19), 4-2 | Griffith Stadium (5-1) | 26-10 | Won 3 |
| » Starters: Waite Hoyt vs Tom Zachary | First | -- |
| Wednesday, May 30 |
| » Defeated Senators (14-20), 6-4 | Griffith Stadium (6-1) | 27-10 | Won 4 |
| » Starters: Herb Pennock vs Walter Johnson | First | -- |
| » Defeated Senators (14-21), 9-5 | Griffith Stadium (7-1) | 28-10 | Won 5 |
| » Starters: Joe Bush vs George Mogridge | First | -- |
| Thursday, May 31 |
| » Defeated Red Sox (13-21), 8-1 | Yankee Stadium (8-4) | 29-10 | Won 6 |
| » Starters: George Murray vs Bob Shawkey | First | -- |
| Friday, June 1 |
| » Lost to Red Sox (14-21), 5-0 | Yankee Stadium (8-5) | 29-11 | |
| » Starters: Jack Quinn vs Sam Jones | First | -- |
| Saturday, June 2 |
| » Lost to Red Sox (15-21), 7-3 | Yankee Stadium (8-6) | 29-12 | Lost 2 |
| » Starters: Howard Ehmke vs Waite Hoyt | First | -- |
| Monday, June 4 |
| » Lost to Senators (17-24), 5-2 | Griffith Stadium (7-2) | 29-13 | Lost 3 |
| » Starters: Joe Bush vs Paul Zahniser | First | -- |
| Tuesday, June 5 |
| » Defeated White Sox (15-25), 7-6 | Yankee Stadium (9-6) | 30-13 | |
| » Starters: Charlie Robertson vs Bob Shawkey | First | -- |
| Wednesday, June 6 |
| » Lost to White Sox (16-25), 4-1 | Yankee Stadium (9-7) | 30-14 | |
| » Starters: Red Faber vs Herb Pennock | First | -- |
| Friday, June 8 |
| » Lost to White Sox (17-25), 7-3 | Yankee Stadium (9-8) | 30-15 | Lost 2 |
| » Starters: Mike Cvengros vs Sam Jones | First | -- |
| Saturday, June 9 |
| » Lost to Indians (26-21), 13-3 | Yankee Stadium (9-9) | 30-16 | Lost 3 |
| » Starters: George Uhle vs Joe Bush | First | -- |
| » Major-league debuts: George Pipgras (Yankees) |
| Sunday, June 10 |
| » Defeated Indians (26-22), 8-7 | Yankee Stadium (10-9) | 31-16 | |
| » Starters: Stan Coveleski vs Waite Hoyt | First | -- |
| Monday, June 11 |
| » Lost to Indians (27-22), 4-3 | Yankee Stadium (10-10) | 31-17 | |
| » Starters: Sherry Smith vs Herb Pennock | First | -- |
| Tuesday, June 12 |
| » Lost to Indians (28-22), 8-4 | Yankee Stadium (10-11) | 31-18 | Lost 2 |
| » Starters: George Uhle vs Bob Shawkey | First | -- |
| Wednesday, June 13 |
| » Defeated Browns (22-26), 5-0 | Yankee Stadium (11-11) | 32-18 | |
| » Starters: Urban Shocker vs Joe Bush | First | -- |
| Thursday, June 14 |
| » Lost to Browns (23-26), 3-1 | Yankee Stadium (11-12) | 32-19 | |
| » Starters: Hub Pruett vs Waite Hoyt | First | -- |
| Friday, June 15 |
| » Defeated Browns (23-27), 10-0 | Yankee Stadium (12-12) | 33-19 | |
| » Starters: Elam Vangilder vs Herb Pennock | First | -- |
| Saturday, June 16 |
| » Defeated Browns (23-28), 9-4 | Yankee Stadium (13-12) | 34-19 | Won 2 |
| » Starters: Bill Bayne vs Bob Shawkey | First | -- |
| Future Yankee Allie Clark is born in South Amboy, NJ. |
| Sunday, June 17 |
| » Defeated Tigers (25-29), 9-0 | Yankee Stadium (14-12) | 35-19 | Won 3 |
| » Starters: Hooks Dauss vs Joe Bush | First | -- |
| Monday, June 18 |
| » Lost to Tigers (26-29), 11-3 | Yankee Stadium (14-13) | 35-20 | |
| » Starters: Ken Holloway vs Waite Hoyt | First | -- |
| Tuesday, June 19 |
| » Defeated Tigers (26-30), 6-5 | Yankee Stadium (15-13) | 36-20 | |
| » Starters: Bert Cole vs Sam Jones | First | -- |
| Wednesday, June 20 |
| » Lost to Tigers (27-30), 9-7 | Yankee Stadium (15-14) | 36-21 | |
| » Starters: Herman Pillette vs Herb Pennock | First | -- |
| Friday, June 22 |
| » Defeated Red Sox (21-31), 4-2 | Fenway Park (2-2) | 37-21 | |
| » Starters: Bob Shawkey vs Jack Quinn | First | -- |
| Saturday, June 23 |
| » Defeated Red Sox (21-32), 4-0 | Fenway Park (3-2) | 38-21 | Won 2 |
| » Starters: Joe Bush vs Howard Ehmke | First | -- |
| Monday, June 25 |
| » Defeated Red Sox (21-33), 14-6 | Fenway Park (4-2) | 39-21 | Won 3 |
| » Starters: Sam Jones vs Bill Piercy | First | -- |
| Tuesday, June 26 |
| » Lost to Red Sox (22-33), 3-1 | Fenway Park (4-3) | 39-22 | |
| » Starters: Waite Hoyt vs Jack Quinn | First | -- |
| Thursday, June 28 |
| » Defeated Athletics (34-28), 4-2 | Yankee Stadium (16-14) | 40-22 | |
| » Starters: Eddie Rommel vs Bob Shawkey | First | -- |
| Friday, June 29 |
| » Defeated Athletics (34-29), 10-9 | Yankee Stadium (17-14) | 41-22 | Won 2 |
| » Starters: Rube Walberg vs Joe Bush | First | -- |
| Saturday, June 30 |
| » Defeated Athletics (34-30), 6-1 | Yankee Stadium (18-14) | 42-22 | Won 3 |
| » Starters: Slim Harriss vs Herb Pennock | First | -- |
| Sunday, July 1 |
| » Defeated Athletics (34-31), 4-0 | Yankee Stadium (19-14) | 43-22 | Won 4 |
| » Starters: Eddie Rommel vs Sam Jones | First | -- |
| Monday, July 2 |
| » Defeated Senators (30-36), 13-1 | Yankee Stadium (20-14) | 44-22 | Won 5 |
| » Starters: Tom Zachary vs Bob Shawkey | First | -- |
| » Major-league debuts: Mike Gazella (Yankees) |
| Tuesday, July 3 |
| » Defeated Senators (30-37), 2-1 | Yankee Stadium (21-14) | 45-22 | Won 6 |
| » Starters: George Mogridge vs Joe Bush | First | -- |
| Wednesday, July 4 |
| » Defeated Senators (30-38), 12-6 | Yankee Stadium (22-14) | 46-22 | Won 7 |
| » Starters: Paul Zahniser vs Herb Pennock | First | -- |
| » Defeated Senators (30-39), 12-2 | Yankee Stadium (23-14) | 47-22 | Won 8 |
| » Starters: Walter Johnson vs Sam Jones | First | -- |
| Friday, July 6 |
| » Defeated Browns (33-37), 5-2 | Sportsman's Park III (5-0) | 48-22 | Won 9 |
| » Starters: Waite Hoyt vs Urban Shocker | First | -- |
| Saturday, July 7 |
| » Lost to Browns (34-37), 13-3 | Sportsman's Park III (5-1) | 48-23 | |
| » Starters: Bob Shawkey vs Elam Vangilder | First | -- |
| » Major-league debuts: Oscar Roettger (Yankees) |
| Sunday, July 8 |
| » Defeated Browns (34-38), 6-4 | Sportsman's Park III (6-1) | 49-23 | |
| » Starters: Joe Bush vs Hub Pruett | First | -- |
| Monday, July 9 |
| » Defeated Browns (34-39), 9-3 | Sportsman's Park III (7-1) | 50-23 | Won 2 |
| » Starters: Herb Pennock vs Dixie Davis | First | -- |
| Tuesday, July 10 |
| » Defeated White Sox (35-36), 3-2 | Comiskey Park I (4-0) | 51-23 | Won 3 |
| » Starters: Sam Jones vs Mike Cvengros | First | -- |
| Wednesday, July 11 |
| » Defeated White Sox (35-37), 3-1 | Comiskey Park I (5-0) | 52-23 | Won 4 |
| » Starters: Waite Hoyt vs Red Faber | First | -- |
| Thursday, July 12 |
| » Defeated White Sox (35-38), 10-6 | Comiskey Park I (6-0) | 53-23 | Won 5 |
| » Starters: Bob Shawkey vs Ted Blankenship | First | -- |
| Friday, July 13 |
| » Lost to White Sox (36-38), 4-3 | Comiskey Park I (6-1) | 53-24 | |
| » Starters: Joe Bush vs Charlie Robertson | First | -- |
| Saturday, July 14 |
| » Lost to Indians (44-36), 4-2 | League Park II (2-1) | 53-25 | Lost 2 |
| » Starters: Herb Pennock vs George Uhle | First | -- |
| » Defeated Indians (44-37), 10-7 | League Park II (3-1) | 54-25 | |
| » Starters: Sam Jones vs Sherry Smith | First | -- |
| Sunday, July 15 |
| » Defeated Indians (44-38), 4-2 | League Park II (4-1) | 55-25 | Won 2 |
| » Starters: Waite Hoyt vs Stan Coveleski | First | -- |
| Monday, July 16 |
| » Lost to Indians (45-38), 6-0 | League Park II (4-2) | 55-26 | |
| » Starters: Bob Shawkey vs Stan Coveleski | First | -- |
| » Defeated Indians (45-39), 11-7 | League Park II (5-2) | 56-26 | |
| » Starters: Joe Bush vs Sherry Smith | First | -- |
| Tuesday, July 17 |
| » Lost to Indians (46-39), 13-0 | League Park II (5-3) | 56-27 | |
| » Starters: Carl Mays vs George Uhle | First | -- |
| Wednesday, July 18 |
| » Defeated Tigers (40-42), 4-1 | Tiger Stadium (4-1) | 57-27 | |
| » Starters: Waite Hoyt vs Ken Holloway | First | -- |
| Thursday, July 19 |
| » Lost to Tigers (41-42), 9-2 | Tiger Stadium (4-2) | 57-28 | |
| » Starters: Sam Jones vs Herman Pillette | First | -- |
| Saturday, July 21 |
| » Defeated Tigers (41-43), 3-2 | Tiger Stadium (5-2) | 58-28 | |
| » Starters: Bob Shawkey vs Hooks Dauss | First | -- |
| Sunday, July 22 |
| » Defeated Tigers (41-44), 7-4 | Tiger Stadium (6-2) | 59-28 | Won 2 |
| » Starters: Waite Hoyt vs Syl Johnson | First | -- |
| Tuesday, July 24 |
| » Defeated Athletics (42-46), 9-2 | Shibe Park (2-2) | 60-28 | Won 3 |
| » Starters: Carl Mays vs Eddie Rommel | First | -- |
| Wednesday, July 25 |
| » Defeated Athletics (42-47), 5-4 | Shibe Park (3-2) | 61-28 | Won 4 |
| » Starters: Bob Shawkey vs Bob Hasty | First | -- |
| Thursday, July 26 |
| » Defeated Athletics (42-48), 4-3 | Shibe Park (4-2) | 62-28 | Won 5 |
| » Starters: Sam Jones vs Slim Harriss | First | -- |
| Friday, July 27 |
| » Defeated Athletics (42-49), 7-3 | Shibe Park (5-2) | 63-28 | Won 6 |
| » Starters: Herb Pennock vs Rollie Naylor | First | -- |
| Saturday, July 28 |
| » Lost to White Sox (44-46), 3-1 | Yankee Stadium (23-15) | 63-29 | |
| » Starters: Charlie Robertson vs Waite Hoyt | First | -- |
| Sunday, July 29 |
| » Lost to White Sox (45-46), 3-2 | Yankee Stadium (23-16) | 63-30 | Lost 2 |
| » Starters: Red Faber vs Joe Bush | First | -- |
| » Defeated White Sox (45-47), 8-2 | Yankee Stadium (24-16) | 64-30 | |
| » Starters: Mike Cvengros vs Bob Shawkey | First | -- |
| Monday, July 30 |
| » Defeated White Sox (45-48), 5-3 | Yankee Stadium (25-16) | 65-30 | Won 2 |
| » Starters: Dixie Leverett vs Sam Jones | First | -- |
| Wednesday, August 1 |
| » Lost to Indians (54-45), 5-3 | Yankee Stadium (25-17) | 65-31 | |
| » Starters: Sherry Smith vs Herb Pennock | First | -- |
| Thursday, August 2 |
| » Defeated Indians (54-46), 4-2 | Yankee Stadium (26-17) | 66-31 | |
| » Starters: Jim Joe Edwards vs Waite Hoyt | First | -- |
| Saturday, August 4 |
| » Lost to Indians (55-46), 15-7 | Yankee Stadium (26-18) | 66-32 | |
| » Starters: George Uhle vs Bob Shawkey | First | -- |
| Sunday, August 5 |
| » Defeated Browns (51-48), 9-8 | Yankee Stadium (27-18) | 67-32 | |
| » Starters: Ray Kolp vs Sam Jones | First | -- |
| Monday, August 6 |
| » Defeated Browns (51-49), 5-3 | Yankee Stadium (28-18) | 68-32 | Won 2 |
| » Starters: Urban Shocker vs Joe Bush | First | -- |
| Tuesday, August 7 |
| » Lost to Browns (52-49), 12-10 | Yankee Stadium (28-19) | 68-33 | |
| » Starters: Rasty Wright vs Bob Shawkey | First | -- |
| Wednesday, August 8 |
| » Lost to Browns (53-49), 4-3 | Yankee Stadium (28-20) | 68-34 | Lost 2 |
| » Starters: Dixie Davis vs Herb Pennock | First | -- |
| Thursday, August 9 |
| » Lost to Tigers (49-49), 11-3 | Yankee Stadium (28-21) | 68-35 | Lost 3 |
| » Starters: Syl Johnson vs Waite Hoyt | First | -- |
| Friday, August 10 |
| Future Yankee Bob Porterfield is born in Newport, VA. |
| Saturday, August 11 |
| » Defeated Tigers (49-50), 10-4 | Yankee Stadium (29-21) | 69-35 | |
| » Starters: Herman Pillette vs Joe Bush | First | -- |
| » Defeated Tigers (49-51), 9-8 | Yankee Stadium (30-21) | 70-35 | Won 2 |
| » Starters: Hooks Dauss vs Sam Jones | First | -- |
| Sunday, August 12 |
| » Lost to Tigers (50-51), 5-2 | Yankee Stadium (30-22) | 70-36 | |
| » Starters: Syl Johnson vs Joe Bush | First | -- |
| Wednesday, August 15 |
| » Lost to Browns (54-51), 5-3 | Sportsman's Park III (7-2) | 70-37 | Lost 2 |
| » Starters: Waite Hoyt vs Urban Shocker | First | -- |
| Thursday, August 16 |
| » Defeated Browns (54-52), 3-1 | Sportsman's Park III (8-2) | 71-37 | |
| » Starters: Herb Pennock vs Dave Danforth | First | -- |
| Friday, August 17 |
| » Defeated Browns (54-53), 5-4 | Sportsman's Park III (9-2) | 72-37 | Won 2 |
| » Starters: Joe Bush vs Elam Vangilder | First | -- |
| Saturday, August 18 |
| » Defeated White Sox (51-59), 6-5 | Comiskey Park I (7-1) | 73-37 | Won 3 |
| » Starters: Sam Jones vs Mike Cvengros | First | -- |
| Sunday, August 19 |
| » Lost to White Sox (52-59), 4-3 | Comiskey Park I (7-2) | 73-38 | |
| » Starters: Waite Hoyt vs Charlie Robertson | First | -- |
| Monday, August 20 |
| » Defeated White Sox (52-60), 16-5 | Comiskey Park I (8-2) | 74-38 | |
| » Starters: Herb Pennock vs Red Faber | First | -- |
| Wednesday, August 22 |
| » Lost to Tigers (56-53), 6-3 | Tiger Stadium (6-3) | 74-39 | |
| » Starters: Joe Bush vs Syl Johnson | First | -- |
| Thursday, August 23 |
| » Lost to Tigers (57-53), 2-1 | Tiger Stadium (6-4) | 74-40 | Lost 2 |
| » Starters: Bob Shawkey vs Hooks Dauss | First | -- |
| Friday, August 24 |
| » Defeated Tigers (57-54), 7-1 | Tiger Stadium (7-4) | 75-40 | |
| » Starters: Herb Pennock vs Herman Pillette | First | -- |
| Saturday, August 25 |
| » Lost to Indians (64-54), 5-2 | League Park II (5-4) | 75-41 | |
| » Starters: Sam Jones vs Dan Boone | First | -- |
| Sunday, August 26 |
| » Lost to Indians (65-54), 4-3 | League Park II (5-5) | 75-42 | Lost 2 |
| » Starters: Joe Bush vs George Uhle | First | -- |
| Monday, August 27 |
| » Defeated Indians (65-55), 10-3 | League Park II (6-5) | 76-42 | |
| » Starters: Bob Shawkey vs Jim Joe Edwards | First | -- |
| Thursday, August 30 |
| » Defeated Senators (57-63), 4-3 | Yankee Stadium (31-22) | 77-42 | Won 2 |
| » Starters: Tom Zachary vs Herb Pennock | First | -- |
| Friday, August 31 |
| » Defeated Senators (57-64), 4-2 | Yankee Stadium (32-22) | 78-42 | Won 3 |
| » Starters: Paul Zahniser vs Sam Jones | First | -- |
| Saturday, September 1 |
| » Defeated Senators (57-65), 6-1 | Yankee Stadium (33-22) | 79-42 | Won 4 |
| » Starters: Allan Russell vs Waite Hoyt | First | -- |
| Sunday, September 2 |
| » Lost to Senators (58-65), 7-2 | Griffith Stadium (7-3) | 79-43 | |
| » Starters: Joe Bush vs George Mogridge | First | -- |
| Monday, September 3 |
| » Defeated Athletics (52-69), 2-1 | Shibe Park (6-2) | 80-43 | |
| » Starters: Bob Shawkey vs Fred Heimach | First | -- |
| » Defeated Athletics (52-70), 7-4 | Shibe Park (7-2) | 81-43 | Won 2 |
| » Starters: Herb Pennock vs Rube Walberg | First | -- |
| Tuesday, September 4 |
| » Defeated Athletics (52-71), 2-0 | Shibe Park (8-2) | 82-43 | Won 3 |
| » Starters: Sam Jones vs Bob Hasty | First | -- |
| Wednesday, September 5 |
| » Defeated Athletics (52-72), 6-3 | Shibe Park (9-2) | 83-43 | Won 4 |
| » Starters: Waite Hoyt vs Hank Hulvey | First | -- |
| » Major-league debuts: Hank Hulvey (Athletics) |
| Saturday, September 8 |
| » Lost to Senators (62-66), 4-0 | Griffith Stadium (7-4) | 83-44 | |
| » Starters: Herb Pennock vs Paul Zahniser | First | -- |
| Sunday, September 9 |
| » Defeated Red Sox (49-76), 6-2 | Yankee Stadium (34-22) | 84-44 | |
| » Starters: Curt Fullerton vs Joe Bush | First | -- |
| » Defeated Red Sox (49-77), 4-0 | Yankee Stadium (35-22) | 85-44 | Won 2 |
| » Starters: George Murray vs Bob Shawkey | First | -- |
| Monday, September 10 |
| » Defeated Red Sox (49-78), 8-1 | Yankee Stadium (36-22) | 86-44 | Won 3 |
| » Starters: Jack Quinn vs Sam Jones | First | -- |
| Tuesday, September 11 |
| » Lost to Red Sox (50-78), 3-0 | Yankee Stadium (36-23) | 86-45 | |
| » Starters: Howard Ehmke vs George Pipgras | First | -- |
| Wednesday, September 12 |
| » Defeated White Sox (58-70), 2-1 | Yankee Stadium (37-23) | 87-45 | |
| » Starters: Charlie Robertson vs Waite Hoyt | First | -- |
| » Defeated White Sox (58-71), 5-3 | Yankee Stadium (38-23) | 88-45 | Won 2 |
| » Starters: Mike Cvengros vs Herb Pennock | First | -- |
| Thursday, September 13 |
| » Defeated White Sox (58-72), 9-5 | Yankee Stadium (39-23) | 89-45 | Won 3 |
| » Starters: Ted Blankenship vs Joe Bush | First | -- |
| Friday, September 14 |
| » Lost to White Sox (59-72), 7-4 | Yankee Stadium (39-24) | 89-46 | |
| » Starters: Dixie Leverett vs Bob Shawkey | First | -- |
| Saturday, September 15 |
| » Defeated White Sox (59-73), 10-4 | Yankee Stadium (40-24) | 90-46 | |
| » Starters: Charlie Robertson vs Sam Jones | First | -- |
| Sunday, September 16 |
| » Defeated Indians (71-61), 4-2 | Yankee Stadium (41-24) | 91-46 | Won 2 |
| » Starters: George Uhle vs Waite Hoyt | First | -- |
| » Defeated Indians (71-62), 3-2 | Yankee Stadium (42-24) | 92-46 | Won 3 |
| » Starters: Jim Joe Edwards vs Herb Pennock | First | -- |
| Monday, September 17 |
| » Lost to Indians (72-62), 6-2 | Yankee Stadium (42-25) | 92-47 | |
| » Starters: Sherry Smith vs Joe Bush | First | -- |
| Tuesday, September 18 |
| » Lost to Indians (73-62), 8-3 | Yankee Stadium (42-26) | 92-48 | Lost 2 |
| » Starters: Joe Shaute vs Bob Shawkey | First | -- |
| Thursday, September 20 |
| » Defeated Browns (68-69), 4-3 | Yankee Stadium (43-26) | 93-48 | |
| » Starters: Elam Vangilder vs Sam Jones | First | -- |
| Sunday, September 23 |
| » Major-league debuts: Ted Wingfield (Senators) |
| Monday, September 24 |
| » Defeated Tigers (72-69), 12-4 | Yankee Stadium (44-26) | 94-48 | Won 2 |
| » Starters: Bert Cole vs Waite Hoyt | First | -- |
| Tuesday, September 25 |
| » Lost to Tigers (73-69), 5-4 | Yankee Stadium (44-27) | 94-49 | |
| » Starters: Earl Whitehill vs Herb Pennock | First | -- |
| Wednesday, September 26 |
| » Lost to Tigers (74-69), 8-3 | Yankee Stadium (44-28) | 94-50 | Lost 2 |
| » Starters: Ray Francis vs Joe Bush | First | -- |
| Thursday, September 27 |
| » Defeated Red Sox (58-87), 8-3 | Fenway Park (5-3) | 95-50 | |
| » Starters: George Pipgras vs Bill Piercy | First | -- |
| Friday, September 28 |
| » Defeated Red Sox (58-88), 24-4 | Fenway Park (6-3) | 96-50 | Won 2 |
| » Starters: Sam Jones vs Howard Ehmke | First | -- |
| Saturday, September 29 |
| » Lost to Red Sox (59-88), 5-4 | Fenway Park (6-4) | 96-51 | |
| » Starters: Waite Hoyt vs Jack Quinn | First | -- |
| » Lost to Red Sox (60-88), 3-2 | Fenway Park (6-5) | 96-52 | Lost 2 |
| » Starters: Bob Shawkey vs George Murray | First | -- |
| Thursday, October 4 |
| » Lost to Athletics (68-81), 7-6 | Yankee Stadium (44-29) | 96-53 | Lost 3 |
| » Starters: Bob Hasty vs Carl Mays | First | -- |
| Friday, October 5 |
| » Defeated Athletics (68-82), 8-4 | Yankee Stadium (45-29) | 97-53 | |
| » Starters: Rollie Naylor vs Bob Shawkey | First | -- |
| Saturday, October 6 |
| » Defeated Athletics (68-83), 3-1 | Yankee Stadium (46-29) | 98-53 | Won 2 |
| » Starters: Bob Hasty vs Herb Pennock | First | -- |
| Sunday, October 7 |
| » Lost to Athletics (69-83), 9-7 | Yankee Stadium (46-30) | 98-54 | |
| » Starters: Slim Harriss vs Waite Hoyt | First | -- |
| Friday, November 9 |
| Future Yankee Ted Sepkowski is born in Baltimore, MD. |
| Sunday, November 25 |
| Future Yankee Archie Wilson is born in Los Angeles, CA. |
| Sunday, December 9 |
| Former Yankee Wild Bill Donovan dies in Forsyth, NY at the age of 48. |
Game information provided by Retrosheet (www.retrosheet.org) |
