| Sunday, January 21 |
| Future Senator Sam Mele is born in Astoria, NY. |
| Wednesday, April 18 |
| » Lost to Athletics (1-0), 3-1 | Shibe Park (0-1) | 0-1 | |
| » Starters: Walter Johnson vs Slim Harriss | Second | 1 out |
| » Major-league debuts: Pep Conroy (Senators) |
| Thursday, April 19 |
| » Lost to Athletics (2-0), 4-2 | Shibe Park (0-2) | 0-2 | Lost 2 |
| » Starters: George Mogridge vs Bob Hasty | Second | 2 out |
| Friday, April 20 |
| » Lost to Athletics (3-0), 6-2 | Shibe Park (0-3) | 0-3 | Lost 3 |
| » Starters: Bonnie Hollingsworth vs Fred Heimach | Fourth | 3 out |
| Saturday, April 21 |
| » Defeated Athletics (3-1), 6-4 | Shibe Park (1-3) | 1-3 | |
| » Starters: Tom Zachary vs Eddie Rommel | Third | 3 out |
| Sunday, April 22 |
| » Defeated Yankees (4-1), 4-3 | Yankee Stadium (1-0) | 2-3 | Won 2 |
| » Starters: Walter Johnson vs Bob Shawkey | Fifth | 3 out |
| Future Senator Preston Gomez is born in Preston, Cuba. |
| Monday, April 23 |
| » Defeated Yankees (4-2), 2-1 | Yankee Stadium (2-0) | 3-3 | Won 3 |
| » Starters: Cy Warmoth vs Joe Bush | Fourth | 3 out |
| Tuesday, April 24 |
| » Lost to Yankees (5-2), 4-0 | Yankee Stadium (2-1) | 3-4 | |
| » Starters: George Mogridge vs Sam Jones | Fifth | 3 out |
| Wednesday, April 25 |
| » Lost to Yankees (6-2), 7-1 | Yankee Stadium (2-2) | 3-5 | Lost 2 |
| » Starters: Bonnie Hollingsworth vs Herb Pennock | Fourth | 3 out |
| Thursday, April 26 |
| » Defeated Athletics (4-4), 2-1 | Griffith Stadium (1-0) | 4-5 | |
| » Starters: Slim Harriss vs Tom Zachary | Fifth | 3 out |
| Friday, April 27 |
| » Tied Athletics, 10-10 | Griffith Stadium (1-0) | 4-5 | |
| » Starters: Walt Kinney vs Walter Johnson | Fifth | 3½ out |
| Future Senator Kite Thomas is born in Kansas City, KS. |
| Sunday, April 29 |
| » Lost to Athletics (5-4), 3-2 | Griffith Stadium (1-1) | 4-6 | |
| » Starters: Bob Hasty vs Bonnie Hollingsworth | Fifth | 4 out |
| Monday, April 30 |
| » Lost to Yankees (8-4), 17-4 | Griffith Stadium (1-2) | 4-7 | Lost 2 |
| » Starters: Sam Jones vs Cy Warmoth | Fifth | 5 out |
| Tuesday, May 1 |
| » Lost to Yankees (9-4), 8-7 | Griffith Stadium (1-3) | 4-8 | Lost 3 |
| » Starters: Carl Mays vs Tom Zachary | Sixth | 5 out |
| Wednesday, May 2 |
| » Defeated Yankees (9-5), 3-0 | Griffith Stadium (2-3) | 5-8 | |
| » Starters: Bob Shawkey vs Walter Johnson | Fourth | 4 out |
| Thursday, May 3 |
| » Lost to Yankees (10-5), 3-2 | Griffith Stadium (2-4) | 5-9 | |
| » Starters: Herb Pennock vs Cy Warmoth | Sixth | 5 out |
| Friday, May 4 |
| » Defeated Red Sox (6-9), 7-4 | Griffith Stadium (3-4) | 6-9 | |
| » Starters: Alex Ferguson vs Bonnie Hollingsworth | Fifth | 4 out |
| Saturday, May 5 |
| » Lost to Red Sox (7-9), 4-1 | Griffith Stadium (3-5) | 6-10 | |
| » Starters: Howard Ehmke vs Tom Zachary | Fifth | 4½ out |
| Sunday, May 6 |
| » Defeated Red Sox (7-10), 4-1 | Griffith Stadium (4-5) | 7-10 | |
| » Starters: George Murray vs Walter Johnson | Fourth | 3½ out |
| Tuesday, May 8 |
| » Defeated Tigers (12-9), 8-2 | Tiger Stadium (1-0) | 8-10 | Won 2 |
| » Starters: Cy Warmoth vs Syl Johnson | Fourth | 3½ out |
| Friday, May 11 |
| » Defeated Tigers (12-10), 4-1 | Tiger Stadium (2-0) | 9-10 | Won 3 |
| » Starters: Tom Zachary vs Rip Collins | Fourth | 3½ out |
| Sunday, May 13 |
| » Lost to Indians (13-10), 5-2 | League Park II (0-1) | 9-11 | |
| » Starters: Cy Warmoth vs Stan Coveleski | Sixth | 4 out |
| Monday, May 14 |
| » Lost to Indians (14-10), 6-3 | League Park II (0-2) | 9-12 | Lost 2 |
| » Starters: Walter Johnson vs George Uhle | Sixth | 5 out |
| Tuesday, May 15 |
| » Lost to Indians (15-10), 10-9 | League Park II (0-3) | 9-13 | Lost 3 |
| » Starters: George Mogridge vs Jim Joe Edwards | Sixth | 6 out |
| Thursday, May 17 |
| » Defeated White Sox (9-14), 3-2 | Comiskey Park I (1-0) | 10-13 | |
| » Starters: Cy Warmoth vs Sloppy Thurston | Sixth | 6½ out |
| Friday, May 18 |
| » Lost to White Sox (10-14), 14-8 | Comiskey Park I (1-1) | 10-14 | |
| » Starters: George Mogridge vs Mike Cvengros | Sixth | 7½ out |
| » Major-league debuts: Pinky Hargrave and Paul Zahniser (Senators) |
| Saturday, May 19 |
| » Defeated White Sox (10-15), 6-4 | Comiskey Park I (2-1) | 11-14 | |
| » Starters: Walter Johnson vs Charlie Robertson | Fourth | 7½ out |
| Sunday, May 20 |
| » Lost to Browns (12-16), 9-8 | Sportsman's Park III (0-1) | 11-15 | |
| » Starters: Tom Zachary vs Urban Shocker | Sixth | 8½ out |
| Monday, May 21 |
| » Defeated Browns (12-17), 3-2 | Sportsman's Park III (1-1) | 12-15 | |
| » Starters: Cy Warmoth vs Elam Vangilder | Fifth | 8½ out |
| Tuesday, May 22 |
| » Lost to Browns (13-17), 12-7 | Sportsman's Park III (1-2) | 12-16 | |
| » Starters: Paul Zahniser vs Dave Danforth | Sixth | 9½ out |
| Thursday, May 24 |
| » Defeated Red Sox (9-18), 7-1 | Fenway Park (1-0) | 13-16 | |
| » Starters: Tom Zachary vs Alex Ferguson | Fifth | 8½ out |
| Friday, May 25 |
| » Lost to Red Sox (10-18), 6-5 | Fenway Park (1-1) | 13-17 | |
| » Starters: Walter Johnson vs Bill Piercy | Fifth | 8½ out |
| Saturday, May 26 |
| » Defeated Red Sox (10-19), 3-2 | Fenway Park (2-1) | 14-17 | |
| » Starters: George Mogridge vs Howard Ehmke | Fifth | 8½ out |
| Sunday, May 27 |
| » Lost to Yankees (25-10), 8-1 | Griffith Stadium (4-6) | 14-18 | |
| » Starters: Sam Jones vs Cy Warmoth | Fifth | 9½ out |
| Monday, May 28 |
| Future Senator Bob Kuzava is born in Wyandotte, MI. |
| Tuesday, May 29 |
| » Lost to Yankees (26-10), 4-2 | Griffith Stadium (4-7) | 14-19 | Lost 2 |
| » Starters: Waite Hoyt vs Tom Zachary | Sixth | 10½ out |
| Wednesday, May 30 |
| » Lost to Yankees (27-10), 6-4 | Griffith Stadium (4-8) | 14-20 | Lost 3 |
| » Starters: Herb Pennock vs Walter Johnson | Sixth | 12½ out |
| » Lost to Yankees (28-10), 9-5 | Griffith Stadium (4-9) | 14-21 | Lost 4 |
| » Starters: Joe Bush vs George Mogridge | Sixth | 12½ out |
| Friday, June 1 |
| » Lost to Athletics (21-16), 7-4 | Griffith Stadium (4-10) | 14-22 | Lost 5 |
| » Starters: Fred Heimach vs Tom Zachary | Seventh | 13½ out |
| » Lost to Athletics (22-16), 4-2 | Griffith Stadium (4-11) | 14-23 | Lost 6 |
| » Starters: Slim Harriss vs Allan Russell | Seventh | 13½ out |
| Saturday, June 2 |
| » Lost to Athletics (23-16), 7-5 | Griffith Stadium (4-12) | 14-24 | Lost 7 |
| » Starters: Rollie Naylor vs Cy Warmoth | Seventh | 13 out |
| » Defeated Athletics (23-17), 5-3 | Griffith Stadium (5-12) | 15-24 | |
| » Starters: Rube Walberg vs Walter Johnson | Seventh | 13 out |
| Sunday, June 3 |
| » Defeated Athletics (23-18), 6-2 | Griffith Stadium (6-12) | 16-24 | Won 2 |
| » Starters: Bob Hasty vs Bonnie Hollingsworth | Seventh | 12½ out |
| Monday, June 4 |
| » Defeated Yankees (29-13), 5-2 | Griffith Stadium (7-12) | 17-24 | Won 3 |
| » Starters: Joe Bush vs Paul Zahniser | Sixth | 11½ out |
| Tuesday, June 5 |
| » Lost to Tigers (22-22), 3-0 | Griffith Stadium (7-13) | 17-25 | |
| » Starters: Bert Cole vs Tom Zachary | Seventh | 12½ out |
| Wednesday, June 6 |
| » Defeated Tigers (22-23), 5-1 | Griffith Stadium (8-13) | 18-25 | |
| » Starters: Ray Francis vs Walter Johnson | Sixth | 11½ out |
| Thursday, June 7 |
| » Defeated Tigers (22-24), 16-4 | Griffith Stadium (9-13) | 19-25 | Won 2 |
| » Starters: Herman Pillette vs Cy Warmoth | Sixth | 11 out |
| Friday, June 8 |
| » Defeated Tigers (22-25), 7-4 | Griffith Stadium (10-13) | 20-25 | Won 3 |
| » Starters: Hooks Dauss vs Bonnie Hollingsworth | Sixth | 10 out |
| Saturday, June 9 |
| » Lost to Browns (21-24), 5-4 | Griffith Stadium (10-14) | 20-26 | |
| » Starters: Urban Shocker vs Paul Zahniser | Sixth | 10 out |
| Sunday, June 10 |
| » Defeated Browns (21-25), 5-3 | Griffith Stadium (11-14) | 21-26 | |
| » Starters: Elam Vangilder vs Tom Zachary | Sixth | 10 out |
| Tuesday, June 12 |
| » Lost to Browns (22-25), 3-1 | Griffith Stadium (11-15) | 21-27 | |
| » Starters: Dave Danforth vs Walter Johnson | Sixth | 9½ out |
| Thursday, June 14 |
| » Lost to White Sox (19-27), 7-3 | Griffith Stadium (11-16) | 21-28 | Lost 2 |
| » Starters: Dixie Leverett vs Tom Zachary | Seventh | 10 out |
| Friday, June 15 |
| » Defeated White Sox (19-28), 8-6 | Griffith Stadium (12-16) | 22-28 | |
| » Starters: Charlie Robertson vs Cy Warmoth | Sixth | 10 out |
| Saturday, June 16 |
| » Lost to White Sox (20-28), 4-3 | Griffith Stadium (12-17) | 22-29 | |
| » Starters: Red Faber vs Bonnie Hollingsworth | Seventh | 11 out |
| Sunday, June 17 |
| » Lost to White Sox (21-28), 5-3 | Griffith Stadium (12-18) | 22-30 | Lost 2 |
| » Starters: Dixie Leverett vs Skipper Friday | Eighth | 12 out |
| Monday, June 18 |
| » Defeated Indians (30-25), 4-3 | Griffith Stadium (13-18) | 23-30 | |
| » Starters: Stan Coveleski vs Walter Johnson | Seventh | 11 out |
| Tuesday, June 19 |
| » Defeated Indians (30-26), 7-6 | Griffith Stadium (14-18) | 24-30 | Won 2 |
| » Starters: Sherry Smith vs Cy Warmoth | Seventh | 11 out |
| Wednesday, June 20 |
| » Lost to Indians (31-26), 5-1 | Griffith Stadium (14-19) | 24-31 | |
| » Starters: Guy Morton vs George Mogridge | Seventh | 11 out |
| Thursday, June 21 |
| » Defeated Indians (31-27), 6-5 | Griffith Stadium (15-19) | 25-31 | |
| » Starters: George Uhle vs Skipper Friday | Seventh | 10½ out |
| Friday, June 22 |
| » Defeated Athletics (31-26), 3-2 | Shibe Park (2-3) | 26-31 | Won 2 |
| » Starters: Walter Johnson vs Slim Harriss | Sixth | 10½ out |
| Saturday, June 23 |
| » Lost to Athletics (32-26), 10-5 | Shibe Park (2-4) | 26-32 | |
| » Starters: Allan Russell vs Rube Walberg | Sixth | 11½ out |
| Sunday, June 24 |
| » Defeated Athletics (32-27), 8-0 | Griffith Stadium (16-19) | 27-32 | |
| » Starters: Bob Hasty vs George Mogridge | Sixth | 11 out |
| Future Senator Mel Hoderlein is born in Mount Carmel, OH. |
| Monday, June 25 |
| » Lost to Athletics (33-27), 3-0 | Shibe Park (2-5) | 27-33 | |
| » Starters: Bonnie Hollingsworth vs Eddie Rommel | Seventh | 12 out |
| Tuesday, June 26 |
| » Lost to Athletics (34-27), 16-7 | Shibe Park (2-6) | 27-34 | Lost 2 |
| » Starters: Walter Johnson vs Slim Harriss | Seventh | 12 out |
| Thursday, June 28 |
| » Lost to Red Sox (23-33), 3-1 | Griffith Stadium (16-20) | 27-35 | Lost 3 |
| » Starters: Howard Ehmke vs Tom Zachary | Seventh | 13 out |
| Friday, June 29 |
| » Defeated Red Sox (23-34), 2-1 | Griffith Stadium (17-20) | 28-35 | |
| » Starters: Alex Ferguson vs George Mogridge | Seventh | 13 out |
| Saturday, June 30 |
| » Defeated Red Sox (23-35), 2-1 | Griffith Stadium (18-20) | 29-35 | Won 2 |
| » Starters: Jack Quinn vs Walter Johnson | Seventh | 13 out |
| Sunday, July 1 |
| » Defeated Red Sox (23-36), 8-1 | Griffith Stadium (19-20) | 30-35 | Won 3 |
| » Starters: George Murray vs Paul Zahniser | Seventh | 13 out |
| Monday, July 2 |
| » Lost to Yankees (44-22), 13-1 | Yankee Stadium (2-3) | 30-36 | |
| » Starters: Tom Zachary vs Bob Shawkey | Seventh | 14 out |
| » Major-league debuts: Mike Gazella (Yankees) |
| Tuesday, July 3 |
| » Lost to Yankees (45-22), 2-1 | Yankee Stadium (2-4) | 30-37 | Lost 2 |
| » Starters: George Mogridge vs Joe Bush | Sixth | 15 out |
| Wednesday, July 4 |
| » Lost to Yankees (46-22), 12-6 | Yankee Stadium (2-5) | 30-38 | Lost 3 |
| » Starters: Paul Zahniser vs Herb Pennock | Seventh | 17 out |
| » Lost to Yankees (47-22), 12-2 | Yankee Stadium (2-6) | 30-39 | Lost 4 |
| » Starters: Walter Johnson vs Sam Jones | Seventh | 17 out |
| Saturday, July 7 |
| » Defeated White Sox (33-34), 4-0 | Comiskey Park I (3-1) | 31-39 | |
| » Starters: George Mogridge vs Red Faber | Sixth | 16 out |
| » Defeated White Sox (33-35), 3-2 | Comiskey Park I (4-1) | 32-39 | Won 2 |
| » Starters: Tom Zachary vs Ted Blankenship | Sixth | 16 out |
| Sunday, July 8 |
| » Lost to White Sox (34-35), 4-2 | Comiskey Park I (4-2) | 32-40 | |
| » Starters: Walter Johnson vs Charlie Robertson | Seventh | 17 out |
| Monday, July 9 |
| » Lost to White Sox (35-35), 8-1 | Comiskey Park I (4-3) | 32-41 | Lost 2 |
| » Starters: Duke Sedgwick vs Dixie Leverett | Seventh | 18 out |
| Tuesday, July 10 |
| » Lost to Browns (35-39), 9-1 | Sportsman's Park III (1-3) | 32-42 | Lost 3 |
| » Starters: Paul Zahniser vs Urban Shocker | Seventh | 19 out |
| Wednesday, July 11 |
| » Lost to Browns (36-39), 10-4 | Sportsman's Park III (1-4) | 32-43 | Lost 4 |
| » Starters: George Mogridge vs Elam Vangilder | Sixth | 20 out |
| Thursday, July 12 |
| » Lost to Browns (37-39), 8-5 | Sportsman's Park III (1-5) | 32-44 | Lost 5 |
| » Starters: Tom Zachary vs Dixie Davis | Fifth | 21 out |
| Friday, July 13 |
| » Defeated Browns (37-40), 8-4 | Sportsman's Park III (2-5) | 33-44 | |
| » Starters: Duke Sedgwick vs Charlie Root | Fifth | 20 out |
| Saturday, July 14 |
| » Lost to Tigers (38-40), 9-8 | Tiger Stadium (2-1) | 33-45 | |
| » Starters: Walter Johnson vs Bert Cole | Seventh | 20½ out |
| Sunday, July 15 |
| » Lost to Tigers (39-40), 10-2 | Tiger Stadium (2-2) | 33-46 | Lost 2 |
| » Starters: George Mogridge vs Herman Pillette | Seventh | 21½ out |
| Future Senator Bruce Edwards is born in Quincy, IL. |
| Monday, July 16 |
| » Defeated Tigers (39-41), 4-2 | Tiger Stadium (3-2) | 34-46 | |
| » Starters: Tom Zachary vs Hooks Dauss | Seventh | 21 out |
| Future Senator Len Okrie is born in Detroit, MI. |
| Tuesday, July 17 |
| » Lost to Tigers (40-41), 4-2 | Tiger Stadium (3-3) | 34-47 | |
| » Starters: Monroe Mitchell vs Syl Johnson | Seventh | 21 out |
| Wednesday, July 18 |
| » Lost to Indians (47-39), 4-1 | League Park II (0-4) | 34-48 | Lost 2 |
| » Starters: Walter Johnson vs Guy Morton | Seventh | 22 out |
| Thursday, July 19 |
| » Lost to Indians (48-39), 3-2 | League Park II (0-5) | 34-49 | Lost 3 |
| » Starters: Allan Russell vs Stan Coveleski | Seventh | 22 out |
| Friday, July 20 |
| » Defeated Indians (48-40), 12-5 | League Park II (1-5) | 35-49 | |
| » Starters: Tom Zachary vs George Uhle | Seventh | 21½ out |
| Saturday, July 21 |
| » Defeated Indians (48-41), 7-5 | League Park II (2-5) | 36-49 | Won 2 |
| » Starters: Paul Zahniser vs Guy Morton | Seventh | 21½ out |
| Sunday, July 22 |
| » Defeated Indians (48-42), 3-1 | League Park II (3-5) | 37-49 | Won 3 |
| » Starters: Walter Johnson vs Stan Coveleski | Seventh | 21½ out |
| Tuesday, July 24 |
| » Lost to Red Sox (32-53), 6-1 | Fenway Park (2-2) | 37-50 | |
| » Starters: Monroe Mitchell vs Jack Quinn | Seventh | 22½ out |
| Thursday, July 26 |
| » Lost to Red Sox (33-53), 7-6 | Fenway Park (2-3) | 37-51 | Lost 2 |
| » Starters: Tom Zachary vs Alex Ferguson | Seventh | 23½ out |
| » Defeated Red Sox (33-54), 15-3 | Fenway Park (3-3) | 38-51 | |
| » Starters: Walter Johnson vs Bill Piercy | Seventh | 23½ out |
| Friday, July 27 |
| » Defeated Red Sox (33-55), 10-7 | Fenway Park (4-3) | 39-51 | Won 2 |
| » Starters: Paul Zahniser vs Howard Ehmke | Seventh | 23½ out |
| Sunday, July 29 |
| » Defeated Tigers (44-45), 11-1 | Griffith Stadium (20-20) | 40-51 | Won 3 |
| » Starters: Herman Pillette vs George Mogridge | Seventh | 22½ out |
| Monday, July 30 |
| » Defeated Tigers (44-46), 1-0 | Griffith Stadium (21-20) | 41-51 | Won 4 |
| » Starters: Hooks Dauss vs Walter Johnson | Seventh | 22½ out |
| Tuesday, July 31 |
| » Lost to Tigers (45-46), 12-5 | Griffith Stadium (21-21) | 41-52 | |
| » Starters: Ken Holloway vs Tom Zachary | Seventh | 23 out |
| Thursday, August 2 |
| » Defeated Browns (51-45), 5-0 | Griffith Stadium (22-21) | 42-52 | |
| » Starters: Urban Shocker vs Monroe Mitchell | Sixth | 22 out |
| » Defeated Browns (51-46), 2-1 | Griffith Stadium (23-21) | 43-52 | Won 2 |
| » Starters: Dixie Davis vs George Mogridge | Sixth | 22 out |
| Saturday, August 4 |
| » Defeated Browns (51-47), 9-3 | Griffith Stadium (24-21) | 44-52 | Won 3 |
| » Starters: Elam Vangilder vs Tom Zachary | Sixth | 21 out |
| Sunday, August 5 |
| » Defeated Indians (55-47), 6-5 | Griffith Stadium (25-21) | 45-52 | Won 4 |
| » Starters: Stan Coveleski vs Walter Johnson | Sixth | 21 out |
| Monday, August 6 |
| » Lost to Indians (56-47), 5-2 | Griffith Stadium (25-22) | 45-53 | |
| » Starters: Sherry Smith vs George Mogridge | Sixth | 22 out |
| Tuesday, August 7 |
| » Lost to Indians (57-47), 22-2 | Griffith Stadium (25-23) | 45-54 | Lost 2 |
| » Starters: George Uhle vs Monroe Mitchell | Sixth | 22 out |
| » Major-league debuts: Squire Potter (Senators) |
| Thursday, August 9 |
| » Defeated Indians (57-48), 2-1 | Griffith Stadium (26-23) | 46-54 | |
| » Starters: Stan Coveleski vs Walter Johnson | Sixth | 20½ out |
| Friday, August 10 |
| Future Senator Bob Porterfield is born in Newport, VA. |
| Saturday, August 11 |
| » Lost to White Sox (49-53), 10-7 | Griffith Stadium (26-24) | 46-55 | |
| » Starters: Charlie Robertson vs George Mogridge | Sixth | 22 out |
| » Tied White Sox, 2-2 | Griffith Stadium (26-24) | 46-55 | |
| » Starters: Red Faber vs George Mogridge | Sixth | 22 out |
| » Major-league debuts: Firpo Marberry (Senators) |
| Sunday, August 12 |
| » Defeated White Sox (49-54), 9-6 | Griffith Stadium (27-24) | 47-55 | |
| » Starters: Mike Cvengros vs Paul Zahniser | Sixth | 21 out |
| Monday, August 13 |
| » Defeated White Sox (49-55), 5-4 | Griffith Stadium (28-24) | 48-55 | Won 2 |
| » Starters: Ted Blankenship vs Tom Zachary | Sixth | 21 out |
| » Lost to White Sox (50-55), 3-2 | Griffith Stadium (28-25) | 48-56 | |
| » Starters: Dixie Leverett vs Walter Johnson | Sixth | 21 out |
| Wednesday, August 15 |
| » Defeated White Sox (50-56), 5-1 | Comiskey Park I (5-3) | 49-56 | |
| » Starters: George Mogridge vs Charlie Robertson | Sixth | 20½ out |
| » Lost to White Sox (51-56), 4-3 | Comiskey Park I (5-4) | 49-57 | |
| » Starters: Paul Zahniser vs Red Faber | Sixth | 20½ out |
| Thursday, August 16 |
| » Defeated White Sox (51-57), 9-2 | Comiskey Park I (6-4) | 50-57 | |
| » Starters: Allan Russell vs Leon Cadore | Sixth | 20½ out |
| Friday, August 17 |
| » Defeated White Sox (51-58), 6-4 | Comiskey Park I (7-4) | 51-57 | Won 2 |
| » Starters: Walter Johnson vs Dixie Leverett | Fifth | 20½ out |
| Saturday, August 18 |
| » Defeated Browns (54-54), 4-3 | Sportsman's Park III (3-5) | 52-57 | Won 3 |
| » Starters: Paul Zahniser vs Dixie Davis | Fifth | 20½ out |
| Sunday, August 19 |
| » Defeated Browns (54-55), 4-2 | Sportsman's Park III (4-5) | 53-57 | Won 4 |
| » Starters: George Mogridge vs Urban Shocker | Fifth | 19½ out |
| Monday, August 20 |
| » Defeated Browns (54-56), 7-2 | Sportsman's Park III (5-5) | 54-57 | Won 5 |
| » Starters: Monroe Mitchell vs Dave Danforth | Fifth | 19½ out |
| Wednesday, August 22 |
| » Defeated Indians (62-53), 8-5 | League Park II (4-5) | 55-57 | Won 6 |
| » Starters: Tom Zachary vs Jim Joe Edwards | Fifth | 18½ out |
| Thursday, August 23 |
| » Lost to Indians (63-53), 2-1 | League Park II (4-6) | 55-58 | |
| » Starters: George Mogridge vs George Uhle | Fifth | 18½ out |
| Friday, August 24 |
| » Defeated Indians (63-54), 20-8 | League Park II (5-6) | 56-58 | |
| » Starters: Paul Zahniser vs Phil Bedgood | Fifth | 18½ out |
| Saturday, August 25 |
| » Lost to Tigers (58-54), 5-4 | Tiger Stadium (3-4) | 56-59 | |
| » Starters: Walter Johnson vs Syl Johnson | Fifth | 18½ out |
| Sunday, August 26 |
| » Lost to Tigers (59-54), 5-4 | Tiger Stadium (3-5) | 56-60 | Lost 2 |
| » Starters: Tom Zachary vs Bert Cole | Fifth | 18½ out |
| Monday, August 27 |
| » Lost to Tigers (60-54), 9-6 | Tiger Stadium (3-6) | 56-61 | Lost 3 |
| » Starters: Paul Zahniser vs Hooks Dauss | Fifth | 19½ out |
| Tuesday, August 28 |
| » Defeated Tigers (60-55), 10-9 | Tiger Stadium (4-6) | 57-61 | |
| » Starters: George Mogridge vs Ray Francis | Fifth | 19 out |
| Wednesday, August 29 |
| » Lost to Tigers (61-55), 9-6 | Tiger Stadium (4-7) | 57-62 | |
| » Starters: Monroe Mitchell vs Syl Johnson | Fifth | 19½ out |
| Thursday, August 30 |
| » Lost to Yankees (77-42), 4-3 | Yankee Stadium (2-7) | 57-63 | Lost 2 |
| » Starters: Tom Zachary vs Herb Pennock | Fifth | 20½ out |
| Friday, August 31 |
| » Lost to Yankees (78-42), 4-2 | Yankee Stadium (2-8) | 57-64 | Lost 3 |
| » Starters: Paul Zahniser vs Sam Jones | Fifth | 21½ out |
| Saturday, September 1 |
| » Lost to Yankees (79-42), 6-1 | Yankee Stadium (2-9) | 57-65 | Lost 4 |
| » Starters: Allan Russell vs Waite Hoyt | Sixth | 22½ out |
| Sunday, September 2 |
| » Defeated Yankees (79-43), 7-2 | Griffith Stadium (29-25) | 58-65 | |
| » Starters: Joe Bush vs George Mogridge | Fifth | 21½ out |
| Monday, September 3 |
| » Lost to Red Sox (48-71), 5-4 | Fenway Park (4-4) | 58-66 | |
| » Starters: Tom Zachary vs Jack Quinn | Fifth | 22½ out |
| » Defeated Red Sox (48-72), 7-3 | Fenway Park (5-4) | 59-66 | |
| » Starters: Firpo Marberry vs Howard Ehmke | Fifth | 22½ out |
| Tuesday, September 4 |
| » Defeated Red Sox (48-73), 3-1 | Fenway Park (6-4) | 60-66 | Won 2 |
| » Starters: Paul Zahniser vs Curt Fullerton | Fifth | 22½ out |
| Wednesday, September 5 |
| » Defeated Red Sox (48-74), 8-4 | Fenway Park (7-4) | 61-66 | Won 3 |
| » Starters: George Mogridge vs Alex Ferguson | Fifth | 22½ out |
| Saturday, September 8 |
| » Defeated Yankees (83-44), 4-0 | Griffith Stadium (30-25) | 62-66 | Won 4 |
| » Starters: Herb Pennock vs Paul Zahniser | Fifth | 21½ out |
| Sunday, September 9 |
| » Lost to Athletics (54-73), 5-2 | Griffith Stadium (30-26) | 62-67 | |
| » Starters: Bob Hasty vs Tom Zachary | Fifth | 23 out |
| Wednesday, September 12 |
| » Lost to Tigers (66-60), 6-4 | Griffith Stadium (30-27) | 62-68 | Lost 2 |
| » Starters: Hooks Dauss vs George Mogridge | Fifth | 24½ out |
| Thursday, September 13 |
| » Defeated Tigers (66-61), 7-3 | Griffith Stadium (31-27) | 63-68 | |
| » Starters: Syl Johnson vs Walter Johnson | Fifth | 24½ out |
| Friday, September 14 |
| » Lost to Tigers (67-61), 8-3 | Griffith Stadium (31-28) | 63-69 | |
| » Starters: Bert Cole vs Tom Zachary | Fifth | 24½ out |
| Saturday, September 15 |
| » Defeated Tigers (67-62), 9-8 | Griffith Stadium (32-28) | 64-69 | |
| » Starters: Syl Johnson vs Paul Zahniser | Fifth | 24½ out |
| » Major-league debuts: Earl Whitehill (Tigers) |
| Sunday, September 16 |
| » Lost to Browns (67-64), 7-3 | Griffith Stadium (32-29) | 64-70 | |
| » Starters: Dixie Davis vs George Mogridge | Fifth | 26 out |
| Monday, September 17 |
| » Defeated Browns (67-65), 5-4 | Griffith Stadium (33-29) | 65-70 | |
| » Starters: Bill Bayne vs Cy Warmoth | Fifth | 24½ out |
| » Defeated Browns (67-66), 12-2 | Griffith Stadium (34-29) | 66-70 | Won 2 |
| » Starters: Dave Danforth vs Walter Johnson | Fifth | 24½ out |
| » Major-league debuts: George Grant (Browns) |
| Tuesday, September 18 |
| » Lost to Browns (68-66), 5-1 | Griffith Stadium (34-30) | 66-71 | |
| » Starters: Dave Danforth vs Tom Zachary | Fifth | 24 out |
| » Defeated Browns (68-67), 2-1 | Griffith Stadium (35-30) | 67-71 | |
| » Starters: Ray Kolp vs Paul Zahniser | Fifth | 24 out |
| Wednesday, September 19 |
| » Defeated Browns (68-68), 11-0 | Griffith Stadium (36-30) | 68-71 | Won 2 |
| » Starters: Dixie Davis vs George Mogridge | Fifth | 23½ out |
| Saturday, September 22 |
| Future Senator Tom Wright is born in Shelby, NC. |
| Sunday, September 23 |
| » Defeated Indians (73-63), 12-10 | Griffith Stadium (37-30) | 69-71 | Won 3 |
| » Starters: George Uhle vs George Mogridge | Fifth | 24 out |
| » Lost to Indians (74-63), 6-0 | Griffith Stadium (37-31) | 69-72 | |
| » Starters: Jim Joe Edwards vs Walter Johnson | Fifth | 24 out |
| » Major-league debuts: Ted Wingfield (Senators) |
| Monday, September 24 |
| » Lost to White Sox (64-76), 1-0 | Griffith Stadium (37-32) | 69-73 | Lost 2 |
| » Starters: Charlie Robertson vs Paul Zahniser | Fifth | 25 out |
| Tuesday, September 25 |
| » Defeated White Sox (64-77), 5-2 | Griffith Stadium (38-32) | 70-73 | |
| » Starters: Dixie Leverett vs Firpo Marberry | Fifth | 24 out |
| Wednesday, September 26 |
| » Defeated White Sox (64-78), 1-0 | Griffith Stadium (39-32) | 71-73 | Won 2 |
| » Starters: Sloppy Thurston vs Walter Johnson | Fifth | 23 out |
| Saturday, September 29 |
| » Lost to Athletics (64-80), 2-0 | Griffith Stadium (39-33) | 71-74 | |
| » Starters: Bob Hasty vs Paul Zahniser | Fifth | 23½ out |
| Sunday, September 30 |
| » Defeated Athletics (64-81), 7-4 | Griffith Stadium (40-33) | 72-74 | |
| » Starters: Rollie Naylor vs Firpo Marberry | Fifth | 23 out |
| Monday, October 1 |
| » Lost to Athletics (65-81), 4-3 | Shibe Park (2-7) | 72-75 | |
| » Starters: Walter Johnson vs Bob Hasty | Fifth | 23½ out |
| Tuesday, October 2 |
| » Lost to Athletics (66-81), 6-1 | Shibe Park (2-8) | 72-76 | Lost 2 |
| » Starters: George Mogridge vs Dennis Burns | Fifth | 24 out |
| Wednesday, October 3 |
| » Lost to Athletics (67-81), 12-8 | Shibe Park (2-9) | 72-77 | Lost 3 |
| » Starters: Clay Roe vs Roy Meeker | Fifth | 24½ out |
| Thursday, October 4 |
| » Lost to Red Sox (61-88), 7-6 | Griffith Stadium (40-34) | 72-78 | Lost 4 |
| » Starters: Bill Piercy vs Paul Zahniser | Fifth | 24½ out |
| Friday, October 5 |
| » Defeated Red Sox (61-89), 4-2 | Griffith Stadium (41-34) | 73-78 | |
| » Starters: Alex Ferguson vs Walter Johnson | Fifth | 24 out |
| » Defeated Red Sox (61-90), 8-4 | Griffith Stadium (42-34) | 74-78 | Won 2 |
| » Starters: George Murray vs Firpo Marberry | Fifth | 24 out |
| Sunday, October 7 |
| » Defeated Red Sox (61-91), 5-2 | Griffith Stadium (43-34) | 75-78 | Won 3 |
| » Starters: Curt Fullerton vs George Mogridge | Fourth | 23½ out |
| Friday, October 26 |
| Former Senator Jimmy Ryan dies in Chicago, IL at the age of 61. |
| Saturday, November 10 |
| Future Senator Cal Ermer is born in Baltimore, MD. |
| Saturday, November 17 |
| Future Senator Mike Garcia is born in San Gabriel, CA. |
| Sunday, November 25 |
| Future Senator Archie Wilson is born in Los Angeles, CA. |
Game information provided by Retrosheet (www.retrosheet.org) |
