| Sunday, January 21 |
| Future Red Sox Sam Mele is born in Astoria, NY. |
| Tuesday, January 30 |
| Future Red Sox Walt Dropo is born in Moosup, CT. |
| Wednesday, April 18 |
| » Lost to Yankees (1-0), 4-1 | Yankee Stadium (0-1) | 0-1 | |
| » Starters: Howard Ehmke vs Bob Shawkey | Second | 1 out |
| Thursday, April 19 |
| » Lost to Yankees (2-0), 8-2 | Yankee Stadium (0-2) | 0-2 | Lost 2 |
| » Starters: Alex Ferguson vs Joe Bush | Second | 2 out |
| Friday, April 20 |
| » Lost to Yankees (3-0), 4-3 | Yankee Stadium (0-3) | 0-3 | Lost 3 |
| » Starters: Bill Piercy vs Waite Hoyt | Fourth | 3 out |
| » Major-league debuts: Hinkey Haines and Harvey Hendrick (Yankees) |
| Saturday, April 21 |
| » Lost to Yankees (4-0), 7-6 | Yankee Stadium (0-4) | 0-4 | Lost 4 |
| » Starters: Lefty O'Doul vs Carl Mays | Fourth | 4 out |
| Monday, April 23 |
| » Defeated Athletics (3-2), 9-6 | Shibe Park (1-0) | 1-4 | |
| » Starters: Howard Ehmke vs Eddie Rommel | Fifth | 4½ out |
| Tuesday, April 24 |
| » Lost to Athletics (4-2), 7-3 | Shibe Park (1-1) | 1-5 | |
| » Starters: Bill Piercy vs Rollie Naylor | Seventh | 4½ out |
| Wednesday, April 25 |
| » Defeated Athletics (4-3), 3-1 | Shibe Park (2-1) | 2-5 | |
| » Starters: Alex Ferguson vs Curly Ogden | Sixth | 3½ out |
| Thursday, April 26 |
| » Defeated Yankees (6-3), 5-4 | Fenway Park (1-0) | 3-5 | Won 2 |
| » Starters: Waite Hoyt vs Howard Ehmke | Seventh | 3½ out |
| Friday, April 27 |
| » Lost to Yankees (7-3), 4-2 | Fenway Park (1-1) | 3-6 | |
| » Starters: Bob Shawkey vs Curt Fullerton | Seventh | 4½ out |
| Saturday, April 28 |
| » Defeated Yankees (7-4), 5-3 | Fenway Park (2-1) | 4-6 | |
| » Starters: Joe Bush vs George Murray | Fifth | 3½ out |
| Monday, April 30 |
| » Lost to Athletics (6-4), 4-2 | Fenway Park (2-2) | 4-7 | |
| » Starters: Rollie Naylor vs Alex Ferguson | Fifth | 5 out |
| Tuesday, May 1 |
| » Defeated Athletics (6-5), 5-4 | Fenway Park (3-2) | 5-7 | |
| » Starters: Curly Ogden vs Howard Ehmke | Fifth | 4 out |
| Wednesday, May 2 |
| » Lost to Athletics (7-5), 4-3 | Fenway Park (3-3) | 5-8 | |
| » Starters: Eddie Rommel vs George Murray | Fourth | 4 out |
| Thursday, May 3 |
| » Defeated Athletics (7-6), 3-1 | Fenway Park (4-3) | 6-8 | |
| » Starters: Bob Hasty vs Jack Quinn | Fifth | 4 out |
| Friday, May 4 |
| » Lost to Senators (6-9), 7-4 | Griffith Stadium (0-1) | 6-9 | |
| » Starters: Alex Ferguson vs Bonnie Hollingsworth | Fifth | 4 out |
| Saturday, May 5 |
| » Defeated Senators (6-10), 4-1 | Griffith Stadium (1-1) | 7-9 | |
| » Starters: Howard Ehmke vs Tom Zachary | Fourth | 3½ out |
| Sunday, May 6 |
| » Lost to Senators (7-10), 4-1 | Griffith Stadium (1-2) | 7-10 | |
| » Starters: George Murray vs Walter Johnson | Fourth | 3½ out |
| Thursday, May 10 |
| » Lost to White Sox (8-11), 9-7 | Comiskey Park I (0-1) | 7-11 | Lost 2 |
| » Starters: Jack Quinn vs Red Faber | Eighth | 5 out |
| Saturday, May 12 |
| » Lost to Browns (10-12), 2-1 | Sportsman's Park III (0-1) | 7-12 | Lost 3 |
| » Starters: Howard Ehmke vs Elam Vangilder | Eighth | 6 out |
| Sunday, May 13 |
| » Lost to Browns (11-12), 3-0 | Sportsman's Park III (0-2) | 7-13 | Lost 4 |
| » Starters: Bill Piercy vs Urban Shocker | Eighth | 6 out |
| Thursday, May 17 |
| » Lost to Tigers (14-13), 6-2 | Tiger Stadium (0-1) | 7-14 | Lost 5 |
| » Starters: George Murray vs Herman Pillette | Eighth | 8½ out |
| Friday, May 18 |
| » Defeated Tigers (14-14), 6-2 | Tiger Stadium (1-1) | 8-14 | |
| » Starters: Howard Ehmke vs Hooks Dauss | Seventh | 8½ out |
| Saturday, May 19 |
| » Lost to Tigers (15-14), 4-0 | Tiger Stadium (1-2) | 8-15 | |
| » Starters: Bill Piercy vs Ken Holloway | Seventh | 9½ out |
| Sunday, May 20 |
| » Lost to Indians (16-14), 1-0 | League Park II (0-1) | 8-16 | Lost 2 |
| » Starters: Jack Quinn vs Stan Coveleski | Eighth | 10½ out |
| Tuesday, May 22 |
| » Lost to Indians (17-14), 3-2 | League Park II (0-2) | 8-17 | Lost 3 |
| » Starters: Howard Ehmke vs George Uhle | Eighth | 12 out |
| Wednesday, May 23 |
| » Defeated Indians (17-15), 8-6 | League Park II (1-2) | 9-17 | |
| » Starters: George Murray vs Joe Shaute | Seventh | 11½ out |
| Thursday, May 24 |
| » Lost to Senators (13-16), 7-1 | Fenway Park (4-4) | 9-18 | |
| » Starters: Tom Zachary vs Alex Ferguson | Eighth | 11½ out |
| Friday, May 25 |
| » Defeated Senators (13-17), 6-5 | Fenway Park (5-4) | 10-18 | |
| » Starters: Walter Johnson vs Bill Piercy | Eighth | 10½ out |
| Saturday, May 26 |
| » Lost to Senators (14-17), 3-2 | Fenway Park (5-5) | 10-19 | |
| » Starters: George Mogridge vs Howard Ehmke | Eighth | 11½ out |
| Monday, May 28 |
| » Defeated Athletics (19-14), 8-6 | Shibe Park (3-1) | 11-19 | |
| » Starters: Jack Quinn vs Slim Harriss | Eighth | 11½ out |
| Tuesday, May 29 |
| » Lost to Athletics (20-14), 3-1 | Shibe Park (3-2) | 11-20 | |
| » Starters: Bill Piercy vs Rollie Naylor | Eighth | 12½ out |
| Wednesday, May 30 |
| » Defeated Athletics (20-15), 6-5 | Shibe Park (4-2) | 12-20 | |
| » Starters: Howard Ehmke vs Bob Hasty | Seventh | 12½ out |
| » Defeated Athletics (20-16), 6-2 | Shibe Park (5-2) | 13-20 | Won 2 |
| » Starters: Alex Ferguson vs Eddie Rommel | Seventh | 12½ out |
| Thursday, May 31 |
| » Lost to Yankees (29-10), 8-1 | Yankee Stadium (0-5) | 13-21 | |
| » Starters: George Murray vs Bob Shawkey | Eighth | 13½ out |
| Friday, June 1 |
| » Defeated Yankees (29-11), 5-0 | Yankee Stadium (1-5) | 14-21 | |
| » Starters: Jack Quinn vs Sam Jones | Sixth | 12½ out |
| Saturday, June 2 |
| » Defeated Yankees (29-12), 7-3 | Yankee Stadium (2-5) | 15-21 | Won 2 |
| » Starters: Howard Ehmke vs Waite Hoyt | Sixth | 11½ out |
| Monday, June 4 |
| » Lost to Indians (24-19), 6-5 | Fenway Park (5-6) | 15-22 | |
| » Starters: Guy Morton vs Alex Ferguson | Seventh | 11½ out |
| Tuesday, June 5 |
| » Defeated Indians (24-20), 10-6 | Fenway Park (6-6) | 16-22 | |
| » Starters: George Uhle vs Jack Quinn | Sixth | 11½ out |
| Wednesday, June 6 |
| » Lost to Indians (25-20), 17-4 | Fenway Park (6-7) | 16-23 | |
| » Starters: Stan Coveleski vs Curt Fullerton | Seventh | 11½ out |
| Thursday, June 7 |
| » Defeated Indians (25-21), 7-1 | Fenway Park (7-7) | 17-23 | |
| » Starters: Joe Shaute vs Howard Ehmke | Seventh | 11 out |
| Saturday, June 9 |
| » Major-league debuts: George Pipgras (Yankees) |
| Monday, June 11 |
| » Lost to White Sox (18-25), 5-4 | Fenway Park (7-8) | 17-24 | |
| » Starters: Charlie Robertson vs Jack Quinn | Eighth | 10½ out |
| Tuesday, June 12 |
| » Defeated White Sox (18-26), 10-4 | Fenway Park (8-8) | 18-24 | |
| » Starters: Red Faber vs Howard Ehmke | Seventh | 9½ out |
| Wednesday, June 13 |
| » Defeated White Sox (18-27), 10-9 | Fenway Park (9-8) | 19-24 | Won 2 |
| » Starters: Dixie Leverett vs Alex Ferguson | Sixth | 9½ out |
| Thursday, June 14 |
| » Lost to Tigers (24-27), 4-1 | Fenway Park (9-9) | 19-25 | |
| » Starters: Ken Holloway vs Bill Piercy | Sixth | 9½ out |
| Friday, June 15 |
| » Lost to Tigers (25-27), 2-0 | Fenway Park (9-10) | 19-26 | Lost 2 |
| » Starters: Syl Johnson vs Jack Quinn | Seventh | 10½ out |
| Saturday, June 16 |
| » Defeated Tigers (25-28), 9-1 | Fenway Park (10-10) | 20-26 | |
| » Starters: Herman Pillette vs Howard Ehmke | Sixth | 10½ out |
| » Major-league debuts: Ed Wells (Tigers) |
| Monday, June 18 |
| » Lost to Browns (24-28), 6-2 | Fenway Park (10-11) | 20-27 | |
| » Starters: Urban Shocker vs Alex Ferguson | Eighth | 11½ out |
| » Lost to Browns (25-28), 9-0 | Fenway Park (10-12) | 20-28 | Lost 2 |
| » Starters: Elam Vangilder vs Bill Piercy | Eighth | 11½ out |
| Tuesday, June 19 |
| » Lost to Browns (26-28), 12-6 | Fenway Park (10-13) | 20-29 | Lost 3 |
| » Starters: Hub Pruett vs Jack Quinn | Eighth | 12½ out |
| Wednesday, June 20 |
| » Defeated Browns (26-29), 3-1 | Fenway Park (11-13) | 21-29 | |
| » Starters: Dixie Davis vs Howard Ehmke | Eighth | 11½ out |
| Thursday, June 21 |
| » Lost to Browns (27-29), 3-1 | Fenway Park (11-14) | 21-30 | |
| » Starters: Ray Kolp vs Bill Piercy | Eighth | 12 out |
| Friday, June 22 |
| » Lost to Yankees (37-21), 4-2 | Fenway Park (11-15) | 21-31 | Lost 2 |
| » Starters: Bob Shawkey vs Jack Quinn | Eighth | 13 out |
| Saturday, June 23 |
| » Lost to Yankees (38-21), 4-0 | Fenway Park (11-16) | 21-32 | Lost 3 |
| » Starters: Joe Bush vs Howard Ehmke | Eighth | 14 out |
| Sunday, June 24 |
| Future Red Sox Mel Hoderlein is born in Mount Carmel, OH. |
| Monday, June 25 |
| » Lost to Yankees (39-21), 14-6 | Fenway Park (11-17) | 21-33 | Lost 4 |
| » Starters: Sam Jones vs Bill Piercy | Eighth | 15 out |
| Tuesday, June 26 |
| » Defeated Yankees (39-22), 3-1 | Fenway Park (12-17) | 22-33 | |
| » Starters: Waite Hoyt vs Jack Quinn | Eighth | 14 out |
| Thursday, June 28 |
| » Defeated Senators (27-35), 3-1 | Griffith Stadium (2-2) | 23-33 | Won 2 |
| » Starters: Howard Ehmke vs Tom Zachary | Eighth | 14 out |
| Friday, June 29 |
| » Lost to Senators (28-35), 2-1 | Griffith Stadium (2-3) | 23-34 | |
| » Starters: Alex Ferguson vs George Mogridge | Eighth | 15 out |
| Saturday, June 30 |
| » Lost to Senators (29-35), 2-1 | Griffith Stadium (2-4) | 23-35 | Lost 2 |
| » Starters: Jack Quinn vs Walter Johnson | Eighth | 16 out |
| Sunday, July 1 |
| » Lost to Senators (30-35), 8-1 | Griffith Stadium (2-5) | 23-36 | Lost 3 |
| » Starters: George Murray vs Paul Zahniser | Eighth | 17 out |
| Monday, July 2 |
| » Defeated Athletics (34-32), 7-4 | Fenway Park (13-17) | 24-36 | |
| » Starters: Bob Hasty vs Howard Ehmke | Eighth | 17 out |
| Wednesday, July 4 |
| » Lost to Athletics (35-32), 3-1 | Fenway Park (13-18) | 24-37 | |
| » Starters: Eddie Rommel vs Alex Ferguson | Eighth | 18½ out |
| » Defeated Athletics (35-33), 8-1 | Fenway Park (14-18) | 25-37 | |
| » Starters: Slim Harriss vs Bill Piercy | Eighth | 18½ out |
| Thursday, July 5 |
| » Defeated Athletics (35-34), 7-5 | Fenway Park (15-18) | 26-37 | Won 2 |
| » Starters: Bob Hasty vs Jack Quinn | Seventh | 18 out |
| Friday, July 6 |
| » Lost to Indians (36-35), 5-3 | League Park II (1-3) | 26-38 | |
| » Starters: Howard Ehmke vs George Uhle | Eighth | 19 out |
| Saturday, July 7 |
| » Lost to Indians (37-35), 27-3 | League Park II (1-4) | 26-39 | Lost 2 |
| » Starters: Curt Fullerton vs Stan Coveleski | Seventh | 19½ out |
| » Lost to Indians (38-35), 8-5 | League Park II (1-5) | 26-40 | Lost 3 |
| » Starters: George Murray vs Phil Bedgood | Seventh | 19½ out |
| Sunday, July 8 |
| » Lost to Indians (39-35), 15-10 | League Park II (1-6) | 26-41 | Lost 4 |
| » Starters: Alex Ferguson vs Joe Shaute | Eighth | 20½ out |
| Monday, July 9 |
| » Defeated Indians (39-36), 4-1 | League Park II (2-6) | 27-41 | |
| » Starters: Bill Piercy vs Sherry Smith | Eighth | 20½ out |
| Wednesday, July 11 |
| » Lost to Tigers (36-38), 7-3 | Tiger Stadium (1-3) | 27-42 | |
| » Starters: Howard Ehmke vs Hooks Dauss | Seventh | 22½ out |
| » Lost to Tigers (37-38), 5-1 | Tiger Stadium (1-4) | 27-43 | Lost 2 |
| » Starters: George Murray vs Herman Pillette | Seventh | 22½ out |
| Thursday, July 12 |
| » Defeated Tigers (37-39), 6-5 | Tiger Stadium (2-4) | 28-43 | |
| » Starters: Alex Ferguson vs Ken Holloway | Sixth | 22½ out |
| Friday, July 13 |
| » Defeated Tigers (37-40), 6-4 | Tiger Stadium (3-4) | 29-43 | Won 2 |
| » Starters: Bill Piercy vs Syl Johnson | Sixth | 21½ out |
| Saturday, July 14 |
| » Lost to Browns (38-40), 4-2 | Sportsman's Park III (0-3) | 29-44 | |
| » Starters: Curt Fullerton vs Urban Shocker | Eighth | 22½ out |
| » Lost to Browns (39-40), 5-2 | Sportsman's Park III (0-4) | 29-45 | Lost 2 |
| » Starters: Howard Ehmke vs Dave Danforth | Eighth | 22½ out |
| Sunday, July 15 |
| » Lost to Browns (40-40), 11-0 | Sportsman's Park III (0-5) | 29-46 | Lost 3 |
| » Starters: Jack Quinn vs Elam Vangilder | Eighth | 23½ out |
| » Tied Browns, 6-6 | Sportsman's Park III (0-5) | 29-46 | |
| » Starters: George Murray vs Dixie Davis | Eighth | 23½ out |
| Monday, July 16 |
| » Lost to Browns (41-40), 4-1 | Sportsman's Park III (0-6) | 29-47 | Lost 4 |
| » Starters: Bill Piercy vs Rasty Wright | Eighth | 24 out |
| Future Red Sox Len Okrie is born in Detroit, MI. |
| Tuesday, July 17 |
| » Lost to Browns (42-40), 10-1 | Sportsman's Park III (0-7) | 29-48 | Lost 5 |
| » Starters: Curt Fullerton vs Dave Danforth | Eighth | 24 out |
| Wednesday, July 18 |
| » Defeated White Sox (38-42), 6-3 | Comiskey Park I (1-1) | 30-48 | |
| » Starters: Howard Ehmke vs Charlie Robertson | Eighth | 24½ out |
| » Lost to White Sox (39-42), 11-3 | Comiskey Park I (1-2) | 30-49 | |
| » Starters: Alex Ferguson vs Sloppy Thurston | Eighth | 24½ out |
| Thursday, July 19 |
| » Lost to White Sox (40-42), 8-3 | Comiskey Park I (1-3) | 30-50 | Lost 2 |
| » Starters: Jack Quinn vs Red Faber | Eighth | 24½ out |
| Friday, July 20 |
| » Defeated White Sox (40-43), 5-4 | Comiskey Park I (2-3) | 31-50 | |
| » Starters: Bill Piercy vs Ted Blankenship | Eighth | 24 out |
| Saturday, July 21 |
| » Lost to White Sox (41-43), 8-1 | Comiskey Park I (2-4) | 31-51 | |
| » Starters: George Murray vs Mike Cvengros | Eighth | 25½ out |
| » Lost to White Sox (42-43), 2-1 | Comiskey Park I (2-5) | 31-52 | Lost 2 |
| » Starters: Alex Ferguson vs Charlie Robertson | Eighth | 25½ out |
| Sunday, July 22 |
| » Lost to White Sox (43-43), 9-2 | Comiskey Park I (2-6) | 31-53 | Lost 3 |
| » Starters: Howard Ehmke vs Dixie Leverett | Eighth | 26½ out |
| Tuesday, July 24 |
| » Defeated Senators (37-50), 6-1 | Fenway Park (16-18) | 32-53 | |
| » Starters: Monroe Mitchell vs Jack Quinn | Eighth | 26½ out |
| Thursday, July 26 |
| » Defeated Senators (37-51), 7-6 | Fenway Park (17-18) | 33-53 | Won 2 |
| » Starters: Tom Zachary vs Alex Ferguson | Eighth | 27½ out |
| » Lost to Senators (38-51), 15-3 | Fenway Park (17-19) | 33-54 | |
| » Starters: Walter Johnson vs Bill Piercy | Eighth | 27½ out |
| Future Red Sox Leo Thomas is born in Turlock, CA. |
| Friday, July 27 |
| » Lost to Senators (39-51), 10-7 | Fenway Park (17-20) | 33-55 | Lost 2 |
| » Starters: Paul Zahniser vs Howard Ehmke | Eighth | 28½ out |
| Saturday, July 28 |
| » Defeated Indians (50-45), 10-5 | Fenway Park (18-20) | 34-55 | |
| » Starters: Guy Morton vs Bill Piercy | Eighth | 27½ out |
| Monday, July 30 |
| » Lost to Indians (51-45), 5-4 | Fenway Park (18-21) | 34-56 | |
| » Starters: George Uhle vs Jack Quinn | Eighth | 29 out |
| » Lost to Indians (52-45), 2-0 | Fenway Park (18-22) | 34-57 | Lost 2 |
| » Starters: Stan Coveleski vs Curt Fullerton | Eighth | 29 out |
| Tuesday, July 31 |
| » Lost to Indians (53-45), 5-4 | Fenway Park (18-23) | 34-58 | Lost 3 |
| » Starters: Guy Morton vs Howard Ehmke | Eighth | 29½ out |
| Wednesday, August 1 |
| » Lost to White Sox (46-48), 4-2 | Fenway Park (18-24) | 34-59 | Lost 4 |
| » Starters: Charlie Robertson vs Bill Piercy | Eighth | 29 out |
| » Defeated White Sox (46-49), 7-3 | Fenway Park (19-24) | 35-59 | |
| » Starters: Ted Blankenship vs Alex Ferguson | Eighth | 29 out |
| » Major-league debuts: Buck Crouse (White Sox) |
| Thursday, August 2 |
| » Lost to White Sox (47-49), 9-5 | Fenway Park (19-25) | 35-60 | |
| » Starters: Red Faber vs George Murray | Eighth | 30 out |
| Saturday, August 4 |
| » Defeated White Sox (47-50), 8-1 | Fenway Park (20-25) | 36-60 | |
| » Starters: Dixie Leverett vs Howard Ehmke | Eighth | 29 out |
| Sunday, August 5 |
| » Defeated Tigers (47-47), 3-2 | Tiger Stadium (4-4) | 37-60 | Won 2 |
| » Starters: Jack Quinn vs Syl Johnson | Eighth | 29 out |
| Monday, August 6 |
| » Defeated Tigers (47-48), 2-1 | Fenway Park (21-25) | 38-60 | Won 3 |
| » Starters: Herman Pillette vs Bill Piercy | Eighth | 29 out |
| Wednesday, August 8 |
| » Lost to Tigers (48-48), 4-0 | Fenway Park (21-26) | 38-61 | |
| » Starters: Hooks Dauss vs Howard Ehmke | Eighth | 28 out |
| » Defeated Tigers (48-49), 3-2 | Fenway Park (22-26) | 39-61 | |
| » Starters: Ken Holloway vs Alex Ferguson | Eighth | 28 out |
| Thursday, August 9 |
| » Defeated Browns (53-50), 4-3 | Fenway Park (23-26) | 40-61 | Won 2 |
| » Starters: Urban Shocker vs Howard Ehmke | Eighth | 27 out |
| Friday, August 10 |
| Future Red Sox Bob Porterfield is born in Newport, VA. |
| Saturday, August 11 |
| » Defeated Browns (53-51), 4-3 | Fenway Park (24-26) | 41-61 | Won 3 |
| » Starters: Elam Vangilder vs Jack Quinn | Eighth | 27½ out |
| Sunday, August 12 |
| » Defeated Indians (59-49), 8-3 | League Park II (3-6) | 42-61 | Won 4 |
| » Starters: Bill Piercy vs George Uhle | Eighth | 26½ out |
| Wednesday, August 15 |
| » Defeated Indians (60-51), 8-6 | League Park II (4-6) | 43-61 | Won 5 |
| » Starters: Curt Fullerton vs Stan Coveleski | Eighth | 25½ out |
| Thursday, August 16 |
| » Lost to Indians (61-51), 12-3 | League Park II (4-7) | 43-62 | |
| » Starters: Howard Ehmke vs George Uhle | Eighth | 26½ out |
| Saturday, August 18 |
| » Lost to Tigers (54-52), 10-3 | Tiger Stadium (4-5) | 43-63 | Lost 2 |
| » Starters: Jack Quinn vs Syl Johnson | Eighth | 28 out |
| Sunday, August 19 |
| » Lost to Tigers (55-52), 5-4 | Tiger Stadium (4-6) | 43-64 | Lost 3 |
| » Starters: Alex Ferguson vs Hooks Dauss | Eighth | 28 out |
| Monday, August 20 |
| » Defeated Tigers (55-53), 6-2 | Tiger Stadium (5-6) | 44-64 | |
| » Starters: Bill Piercy vs Herman Pillette | Eighth | 28 out |
| Wednesday, August 22 |
| » Lost to Browns (55-56), 8-7 | Sportsman's Park III (0-8) | 44-65 | |
| » Starters: Howard Ehmke vs Dixie Davis | Eighth | 28½ out |
| » Lost to Browns (56-56), 6-1 | Sportsman's Park III (0-9) | 44-66 | Lost 2 |
| » Starters: Jack Quinn vs Urban Shocker | Eighth | 28½ out |
| Thursday, August 23 |
| » Lost to Browns (57-56), 4-1 | Sportsman's Park III (0-10) | 44-67 | Lost 3 |
| » Starters: Alex Ferguson vs Ray Kolp | Eighth | 28½ out |
| Friday, August 24 |
| » Lost to Browns (58-56), 6-5 | Sportsman's Park III (0-11) | 44-68 | Lost 4 |
| » Starters: Curt Fullerton vs Elam Vangilder | Eighth | 29½ out |
| Saturday, August 25 |
| » Lost to White Sox (54-62), 3-0 | Comiskey Park I (2-7) | 44-69 | Lost 5 |
| » Starters: Howard Ehmke vs Claral Gillenwater | Eighth | 29½ out |
| Sunday, August 26 |
| » Defeated White Sox (54-63), 5-4 | Comiskey Park I (3-7) | 45-69 | |
| » Starters: Jack Quinn vs Dixie Leverett | Eighth | 28½ out |
| Monday, August 27 |
| » Lost to White Sox (55-63), 2-0 | Comiskey Park I (3-8) | 45-70 | |
| » Starters: Alex Ferguson vs Ted Blankenship | Eighth | 29½ out |
| Thursday, August 30 |
| » Defeated Athletics (51-67), 8-1 | Fenway Park (25-26) | 46-70 | |
| » Starters: Rollie Naylor vs Howard Ehmke | Eighth | 29½ out |
| Friday, August 31 |
| » Lost to Athletics (52-67), 3-1 | Fenway Park (25-27) | 46-71 | |
| » Starters: Bob Hasty vs Curt Fullerton | Eighth | 30½ out |
| Saturday, September 1 |
| » Defeated Athletics (52-68), 6-1 | Fenway Park (26-27) | 47-71 | |
| » Starters: Eddie Rommel vs Alex Ferguson | Eighth | 30½ out |
| Monday, September 3 |
| » Defeated Senators (58-66), 5-4 | Fenway Park (27-27) | 48-71 | Won 2 |
| » Starters: Tom Zachary vs Jack Quinn | Eighth | 31 out |
| » Lost to Senators (59-66), 7-3 | Fenway Park (27-28) | 48-72 | |
| » Starters: Firpo Marberry vs Howard Ehmke | Eighth | 31 out |
| Tuesday, September 4 |
| » Lost to Senators (60-66), 3-1 | Fenway Park (27-29) | 48-73 | Lost 2 |
| » Starters: Paul Zahniser vs Curt Fullerton | Eighth | 32 out |
| Wednesday, September 5 |
| » Lost to Senators (61-66), 8-4 | Fenway Park (27-30) | 48-74 | Lost 3 |
| » Starters: George Mogridge vs Alex Ferguson | Eighth | 33 out |
| Thursday, September 6 |
| » Lost to Athletics (53-72), 6-2 | Shibe Park (5-3) | 48-75 | Lost 4 |
| » Starters: Jack Quinn vs Eddie Rommel | Eighth | 33½ out |
| Friday, September 7 |
| » Defeated Athletics (53-73), 4-0 | Shibe Park (6-3) | 49-75 | |
| » Starters: Howard Ehmke vs Slim Harriss | Eighth | 33 out |
| Sunday, September 9 |
| » Lost to Yankees (84-44), 6-2 | Yankee Stadium (2-6) | 49-76 | |
| » Starters: Curt Fullerton vs Joe Bush | Eighth | 34½ out |
| » Lost to Yankees (85-44), 4-0 | Yankee Stadium (2-7) | 49-77 | Lost 2 |
| » Starters: George Murray vs Bob Shawkey | Eighth | 34½ out |
| Monday, September 10 |
| » Lost to Yankees (86-44), 8-1 | Yankee Stadium (2-8) | 49-78 | Lost 3 |
| » Starters: Jack Quinn vs Sam Jones | Eighth | 35½ out |
| Tuesday, September 11 |
| » Defeated Yankees (86-45), 3-0 | Yankee Stadium (3-8) | 50-78 | |
| » Starters: Howard Ehmke vs George Pipgras | Eighth | 34½ out |
| Thursday, September 13 |
| » Defeated Indians (71-58), 9-8 | Fenway Park (28-30) | 51-78 | Won 2 |
| » Starters: George Uhle vs Les Howe | Eighth | 35½ out |
| Friday, September 14 |
| » Defeated Indians (71-59), 4-3 | Fenway Park (29-30) | 52-78 | Won 3 |
| » Starters: Joe Shaute vs Jack Quinn | Eighth | 34½ out |
| Saturday, September 15 |
| » Defeated Indians (71-60), 11-6 | Fenway Park (30-30) | 53-78 | Won 4 |
| » Starters: Guy Morton vs Howard Ehmke | Eighth | 34½ out |
| Monday, September 17 |
| » Lost to White Sox (60-73), 6-1 | Fenway Park (30-31) | 53-79 | |
| » Starters: Sloppy Thurston vs Curt Fullerton | Eighth | 35 out |
| » Defeated White Sox (60-74), 6-5 | Fenway Park (31-31) | 54-79 | |
| » Starters: Mike Cvengros vs Alex Ferguson | Eighth | 35 out |
| Tuesday, September 18 |
| » Lost to White Sox (61-74), 6-2 | Fenway Park (31-32) | 54-80 | |
| » Starters: Ted Blankenship vs Jack Quinn | Eighth | 35 out |
| Wednesday, September 19 |
| » Defeated White Sox (61-75), 2-1 | Fenway Park (32-32) | 55-80 | |
| » Starters: Charlie Robertson vs Howard Ehmke | Eighth | 34½ out |
| Thursday, September 20 |
| » Lost to Tigers (70-66), 5-4 | Fenway Park (32-33) | 55-81 | |
| » Starters: Herman Pillette vs George Murray | Seventh | 35½ out |
| » Tied Tigers, 2-2 | Fenway Park (32-33) | 55-81 | |
| » Starters: Ken Holloway vs Bill Piercy | Seventh | 35½ out |
| Friday, September 21 |
| » Defeated Tigers (70-67), 4-3 | Fenway Park (33-33) | 56-81 | |
| » Starters: Herman Pillette vs Alex Ferguson | Seventh | 35½ out |
| » Lost to Tigers (71-67), 15-6 | Fenway Park (33-34) | 56-82 | |
| » Starters: Ole Olsen vs Curt Fullerton | Seventh | 35½ out |
| Saturday, September 22 |
| » Lost to Tigers (72-67), 10-0 | Fenway Park (33-35) | 56-83 | Lost 2 |
| » Starters: Hooks Dauss vs Curt Fullerton | Eighth | 35½ out |
| » Defeated Tigers (72-68), 9-7 | Fenway Park (34-35) | 57-83 | |
| » Starters: Ken Holloway vs George Murray | Eighth | 35½ out |
| Future Red Sox Tom Wright is born in Shelby, NC. |
| Sunday, September 23 |
| » Major-league debuts: Ted Wingfield (Senators) |
| Monday, September 24 |
| » Lost to Browns (69-69), 6-1 | Fenway Park (34-36) | 57-84 | |
| » Starters: Dave Danforth vs Howard Ehmke | Eighth | 37 out |
| » Lost to Browns (70-69), 4-2 | Fenway Park (34-37) | 57-85 | Lost 2 |
| » Starters: Ray Kolp vs Les Howe | Eighth | 37 out |
| Tuesday, September 25 |
| » Lost to Browns (71-69), 8-2 | Fenway Park (34-38) | 57-86 | Lost 3 |
| » Starters: Elam Vangilder vs Alex Ferguson | Eighth | 37 out |
| Wednesday, September 26 |
| » Defeated Browns (71-70), 3-2 | Fenway Park (35-38) | 58-86 | |
| » Starters: Dixie Davis vs George Murray | Eighth | 36 out |
| Thursday, September 27 |
| » Lost to Yankees (95-50), 8-3 | Fenway Park (35-39) | 58-87 | |
| » Starters: George Pipgras vs Bill Piercy | Eighth | 37 out |
| Friday, September 28 |
| » Lost to Yankees (96-50), 24-4 | Fenway Park (35-40) | 58-88 | Lost 2 |
| » Starters: Sam Jones vs Howard Ehmke | Eighth | 38 out |
| Saturday, September 29 |
| » Defeated Yankees (96-51), 5-4 | Fenway Park (36-40) | 59-88 | |
| » Starters: Waite Hoyt vs Jack Quinn | Eighth | 36 out |
| » Defeated Yankees (96-52), 3-2 | Fenway Park (37-40) | 60-88 | Won 2 |
| » Starters: Bob Shawkey vs George Murray | Eighth | 36 out |
| Thursday, October 4 |
| » Defeated Senators (72-78), 7-6 | Griffith Stadium (3-5) | 61-88 | Won 3 |
| » Starters: Bill Piercy vs Paul Zahniser | Eighth | 35 out |
| Friday, October 5 |
| » Lost to Senators (73-78), 4-2 | Griffith Stadium (3-6) | 61-89 | |
| » Starters: Alex Ferguson vs Walter Johnson | Eighth | 36½ out |
| » Lost to Senators (74-78), 8-4 | Griffith Stadium (3-7) | 61-90 | Lost 2 |
| » Starters: George Murray vs Firpo Marberry | Eighth | 36½ out |
| Sunday, October 7 |
| » Lost to Senators (75-78), 5-2 | Griffith Stadium (3-8) | 61-91 | Lost 3 |
| » Starters: Curt Fullerton vs George Mogridge | Eighth | 37 out |
| Thursday, October 25 |
| Future Red Sox Russ Meyer is born in Peru, IL. Future Red Sox Bobby Thomson is born in Glasgow, Scotland. |
| Sunday, November 25 |
| Future Red Sox Archie Wilson is born in Los Angeles, CA. |
Game information provided by Retrosheet (www.retrosheet.org) |