| Monday, February 20 |
| Future Red Sox Jim Wilson is born in San Diego, CA. |
| Wednesday, April 12 |
| » Lost to Athletics (1-0), 3-2 | Fenway Park (0-1) | 0-1 | |
| » Starters: Rollie Naylor vs Jack Quinn | Second | 1 out |
| Future Red Sox Bill Wight is born in Rio Vista, CA. |
| Thursday, April 13 |
| » Defeated Athletics (1-1), 6-2 | Fenway Park (1-1) | 1-1 | |
| » Starters: Rube Yarrison vs Benn Karr | Second | 1 out |
| Friday, April 14 |
| » Lost to Athletics (2-1), 8-2 | Fenway Park (1-2) | 1-2 | |
| » Starters: Eddie Rommel vs Elmer Myers | Fourth | 1½ out |
| Tuesday, April 18 |
| » Lost to Yankees (3-1), 10-8 | Fenway Park (1-3) | 1-3 | Lost 2 |
| » Starters: Bullet Joe Bush vs Benn Karr | Seventh | 3½ out |
| Wednesday, April 19 |
| » Defeated Yankees (3-2), 5-3 | Fenway Park (2-3) | 2-3 | |
| » Starters: Carl Mays vs Jack Quinn | Fourth | 3 out |
| » Lost to Yankees (4-2), 6-1 | Fenway Park (2-4) | 2-4 | |
| » Starters: Waite Hoyt vs Allen Russell | Fourth | 3 out |
| Thursday, April 20 |
| » Defeated Athletics (4-3), 15-4 | Shibe Park (1-0) | 3-4 | |
| » Starters: Herb Pennock vs Eddie Rommel | Fifth | 3 out |
| Saturday, April 22 |
| » Defeated Athletics (4-4), 7-1 | Shibe Park (2-0) | 4-4 | Won 2 |
| » Starters: Benn Karr vs Slim Harriss | Fourth | 2½ out |
| Monday, April 24 |
| » Lost to Senators (3-8), 11-3 | Griffith Stadium (0-1) | 4-5 | |
| » Starters: Jack Quinn vs George Mogridge | Third | 4 out |
| » Major-league debuts: Ossie Bluege (Senators) |
| Tuesday, April 25 |
| » Lost to Senators (4-8), 10-0 | Griffith Stadium (0-2) | 4-6 | Lost 2 |
| » Starters: Allen Russell vs Tom Phillips | Fourth | 5 out |
| Wednesday, April 26 |
| » Lost to Senators (5-8), 15-6 | Griffith Stadium (0-3) | 4-7 | Lost 3 |
| » Starters: Herb Pennock vs Joe Gleason | Sixth | 5 out |
| Future Red Sox Sam Dente is born in Harrison, NJ. |
| Friday, April 28 |
| » Lost to Yankees (11-3), 10-3 | Polo Grounds V (0-1) | 4-8 | Lost 4 |
| » Starters: Benn Karr vs Bullet Joe Bush | Seventh | 6 out |
| Saturday, April 29 |
| » Defeated Yankees (11-4), 5-2 | Polo Grounds V (1-1) | 5-8 | |
| » Starters: Jack Quinn vs Waite Hoyt | Seventh | 5 out |
| Sunday, April 30 |
| » Defeated Yankees (11-5), 2-1 | Polo Grounds V (2-1) | 6-8 | Won 2 |
| » Starters: Herb Pennock vs Bob Shawkey | Fifth | 4 out |
| Monday, May 1 |
| » Defeated Yankees (11-6), 5-2 | Polo Grounds V (3-1) | 7-8 | Won 3 |
| » Starters: Alex Ferguson vs Carl Mays | Fourth | 4 out |
| Tuesday, May 2 |
| » Lost to Yankees (12-6), 12-6 | Polo Grounds V (3-2) | 7-9 | |
| » Starters: Curt Fullerton vs Sad Sam Jones | Fourth | 4 out |
| Wednesday, May 3 |
| » Defeated Senators (8-12), 8-0 | Fenway Park (3-4) | 8-9 | |
| » Starters: Tom Phillips vs Jack Quinn | Fifth | 3½ out |
| Saturday, May 6 |
| » Defeated Senators (8-13), 1-0 | Fenway Park (4-4) | 9-9 | Won 2 |
| » Starters: Tom Zachary vs Herb Pennock | Fourth | 3½ out |
| Monday, May 8 |
| » Lost to Tigers (8-14), 6-2 | Fenway Park (4-5) | 9-10 | |
| » Starters: Ole Olsen vs Jack Quinn | Fifth | 5 out |
| Tuesday, May 9 |
| » Lost to Tigers (9-14), 6-2 | Fenway Park (4-6) | 9-11 | Lost 2 |
| » Starters: Howard Ehmke vs Alex Ferguson | Fifth | 6 out |
| Wednesday, May 10 |
| » Lost to Tigers (10-14), 10-9 | Fenway Park (4-7) | 9-12 | Lost 3 |
| » Starters: Herman Pillette vs Herb Pennock | Fifth | 6 out |
| Thursday, May 11 |
| » Lost to Tigers (11-14), 5-3 | Fenway Park (4-8) | 9-13 | Lost 4 |
| » Starters: Syl Johnson vs Rip Collins | Sixth | 7 out |
| Friday, May 12 |
| » Defeated White Sox (11-14), 5-0 | Fenway Park (5-8) | 10-13 | |
| » Starters: Doug McWeeny vs Jack Quinn | Fifth | 7 out |
| Saturday, May 13 |
| » Defeated White Sox (11-15), 3-1 | Fenway Park (6-8) | 11-13 | Won 2 |
| » Starters: Dixie Leverett vs Herb Pennock | Fifth | 6 out |
| Monday, May 15 |
| » Defeated White Sox (11-16), 2-0 | Fenway Park (7-8) | 12-13 | Won 3 |
| » Starters: Harry Courtney vs Rip Collins | Fifth | 4½ out |
| Tuesday, May 16 |
| » Lost to Browns (19-11), 6-5 | Fenway Park (7-9) | 12-14 | |
| » Starters: Urban Shocker vs Jack Quinn | Sixth | 5½ out |
| Wednesday, May 17 |
| » Defeated Browns (19-12), 4-3 | Fenway Park (8-9) | 13-14 | |
| » Starters: Elam Vangilder vs Alex Ferguson | Fifth | 5½ out |
| Saturday, May 20 |
| » Lost to Indians (15-18), 5-2 | Fenway Park (8-10) | 13-15 | |
| » Starters: Stan Coveleski vs Bill Piercy | Fifth | 6 out |
| Monday, May 22 |
| » Lost to Indians (16-18), 7-1 | Fenway Park (8-11) | 13-16 | Lost 2 |
| » Starters: Guy Morton vs Jack Quinn | Sixth | 7½ out |
| Tuesday, May 23 |
| » Lost to Indians (17-18), 5-3 | Fenway Park (8-12) | 13-17 | Lost 3 |
| » Starters: George Uhle vs Herb Pennock | Seventh | 7½ out |
| Wednesday, May 24 |
| » Defeated Indians (17-19), 6-2 | Fenway Park (9-12) | 14-17 | |
| » Starters: Jim Bagby vs Rip Collins | Seventh | 6½ out |
| Friday, May 26 |
| » Defeated Athletics (16-18), 7-6 | Fenway Park (10-12) | 15-17 | Won 2 |
| » Starters: Eddie Rommel vs Benn Karr | Sixth | 6 out |
| Saturday, May 27 |
| » Lost to Athletics (17-18), 3-2 | Fenway Park (10-13) | 15-18 | |
| » Starters: Bob Hasty vs Alex Ferguson | Seventh | 7½ out |
| » Lost to Athletics (18-18), 2-1 | Fenway Park (10-14) | 15-19 | Lost 2 |
| » Starters: Rollie Naylor vs Rip Collins | Seventh | 7½ out |
| Monday, May 29 |
| » Lost to Senators (20-22), 2-0 | Fenway Park (10-15) | 15-20 | Lost 3 |
| » Starters: Eric Erickson vs Jack Quinn | Seventh | 7½ out |
| » Defeated Senators (20-23), 9-8 | Fenway Park (11-15) | 16-20 | |
| » Starters: Joe Gleason vs Bill Piercy | Seventh | 7½ out |
| Tuesday, May 30 |
| » Lost to Senators (21-23), 7-4 | Fenway Park (11-16) | 16-21 | |
| » Starters: Tom Zachary vs Herb Pennock | Eighth | 8½ out |
| » Lost to Senators (22-23), 5-3 | Fenway Park (11-17) | 16-22 | Lost 2 |
| » Starters: Jim Brillheart vs Rip Collins | Eighth | 8½ out |
| Wednesday, May 31 |
| » Defeated Senators (22-24), 6-4 | Fenway Park (12-17) | 17-22 | |
| » Starters: Walter Johnson vs Curt Fullerton | Eighth | 8½ out |
| » Lost to Senators (23-24), 7-4 | Fenway Park (12-18) | 17-23 | |
| » Starters: George Mogridge vs Alex Ferguson | Eighth | 8½ out |
| Thursday, June 1 |
| » Lost to Yankees (29-17), 5-4 | Polo Grounds V (3-3) | 17-24 | Lost 2 |
| » Starters: Rip Collins vs Bullet Joe Bush | Eighth | 9½ out |
| Saturday, June 3 |
| » Defeated Yankees (29-18), 6-2 | Polo Grounds V (4-3) | 18-24 | |
| » Starters: Jack Quinn vs Sad Sam Jones | Sixth | 8½ out |
| Sunday, June 4 |
| » Defeated Senators (23-25), 2-1 | Griffith Stadium (1-3) | 19-24 | Won 2 |
| » Starters: Alex Ferguson vs Walter Johnson | Sixth | 8½ out |
| Tuesday, June 6 |
| » Lost to Browns (29-19), 5-2 | Sportsman's Park III (0-1) | 19-25 | |
| » Starters: Herb Pennock vs Urban Shocker | Sixth | 9½ out |
| Wednesday, June 7 |
| » Defeated Browns (29-20), 7-3 | Sportsman's Park III (1-1) | 20-25 | |
| » Starters: Rip Collins vs Dixie Davis | Seventh | 9½ out |
| Thursday, June 8 |
| » Defeated Browns (29-21), 7-5 | Sportsman's Park III (2-1) | 21-25 | Won 2 |
| » Starters: Jack Quinn vs Elam Vangilder | Sixth | 9½ out |
| Friday, June 9 |
| » Lost to Browns (30-21), 8-1 | Sportsman's Park III (2-2) | 21-26 | |
| » Starters: Alex Ferguson vs Dave Danforth | Seventh | 9½ out |
| Saturday, June 10 |
| » Lost to White Sox (22-29), 10-5 | Comiskey Park I (0-1) | 21-27 | Lost 2 |
| » Starters: Allen Russell vs Red Faber | Seventh | 10½ out |
| Sunday, June 11 |
| » Lost to White Sox (23-29), 7-6 | Comiskey Park I (0-2) | 21-28 | Lost 3 |
| » Starters: Rip Collins vs Dixie Leverett | Eighth | 11½ out |
| Monday, June 12 |
| » Lost to White Sox (24-29), 7-6 | Comiskey Park I (0-3) | 21-29 | Lost 4 |
| » Starters: Alex Ferguson vs Ferdie Schupp | Eighth | 11½ out |
| Tuesday, June 13 |
| » Lost to White Sox (25-29), 5-0 | Comiskey Park I (0-4) | 21-30 | Lost 5 |
| » Starters: Bill Piercy vs Charlie Robertson | Seventh | 11½ out |
| Future Red Sox Mel Parnell is born in New Orleans, LA. |
| Wednesday, June 14 |
| » Lost to Indians (27-28), 3-0 | League Park II (0-1) | 21-31 | Lost 6 |
| » Starters: Rip Collins vs Stan Coveleski | Seventh | 11½ out |
| Thursday, June 15 |
| » Defeated Indians (27-29), 8-3 | League Park II (1-1) | 22-31 | |
| » Starters: Jack Quinn vs Duster Mails | Eighth | 10½ out |
| Friday, June 16 |
| » Defeated Indians (27-30), 8-6 | League Park II (2-1) | 23-31 | Won 2 |
| » Starters: Alex Ferguson vs George Uhle | Seventh | 10 out |
| Saturday, June 17 |
| » Lost to Indians (28-30), 5-4 | League Park II (2-2) | 23-32 | |
| » Starters: Rip Collins vs Dave Keefe | Seventh | 10 out |
| Sunday, June 18 |
| » Lost to Tigers (31-28), 8-1 | Tiger Stadium (0-1) | 23-33 | Lost 2 |
| » Starters: Herb Pennock vs Ole Olsen | Eighth | 11 out |
| Monday, June 19 |
| » Lost to Tigers (32-28), 11-9 | Tiger Stadium (0-2) | 23-34 | Lost 3 |
| » Starters: Jack Quinn vs Lil Stoner | Eighth | 12 out |
| Tuesday, June 20 |
| » Lost to Tigers (33-28), 9-8 | Tiger Stadium (0-3) | 23-35 | Lost 4 |
| » Starters: Alex Ferguson vs Hooks Dauss | Eighth | 13 out |
| Wednesday, June 21 |
| » Defeated Tigers (33-29), 9-8 | Tiger Stadium (1-3) | 24-35 | |
| » Starters: Rip Collins vs Ole Olsen | Seventh | 12 out |
| Thursday, June 22 |
| » Defeated Yankees (37-28), 6-2 | Fenway Park (13-18) | 25-35 | Won 2 |
| » Starters: Waite Hoyt vs Jack Quinn | Seventh | 11 out |
| Friday, June 23 |
| » Defeated Yankees (37-29), 5-4 | Fenway Park (14-18) | 26-35 | Won 3 |
| » Starters: Carl Mays vs Herb Pennock | Seventh | 10 out |
| Saturday, June 24 |
| » Defeated Yankees (37-30), 12-7 | Fenway Park (15-18) | 27-35 | Won 4 |
| » Starters: Sad Sam Jones vs Rip Collins | Seventh | 9½ out |
| » Defeated Yankees (37-31), 5-2 | Fenway Park (16-18) | 28-35 | Won 5 |
| » Starters: Bullet Joe Bush vs Bill Piercy | Seventh | 9½ out |
| Monday, June 26 |
| » Lost to Yankees (38-31), 6-4 | Fenway Park (16-19) | 28-36 | |
| » Starters: Bob Shawkey vs Jack Quinn | Seventh | 10 out |
| Tuesday, June 27 |
| » Lost to Athletics (25-34), 4-2 | Shibe Park (2-1) | 28-37 | Lost 2 |
| » Starters: Herb Pennock vs Eddie Rommel | Seventh | 10½ out |
| » Lost to Athletics (26-34), 6-4 | Shibe Park (2-2) | 28-38 | Lost 3 |
| » Starters: Alex Ferguson vs Fred Heimach | Seventh | 10½ out |
| Wednesday, June 28 |
| » Defeated Athletics (26-35), 4-2 | Shibe Park (3-2) | 29-38 | |
| » Starters: Benn Karr vs Bob Hasty | Seventh | 10½ out |
| Thursday, June 29 |
| » Lost to Athletics (27-35), 10-3 | Shibe Park (3-3) | 29-39 | |
| » Starters: Rip Collins vs Rollie Naylor | Eighth | 11 out |
| Friday, June 30 |
| » Defeated Athletics (27-36), 4-1 | Shibe Park (4-3) | 30-39 | |
| » Starters: Bill Piercy vs Roy Moore | Seventh | 11 out |
| Saturday, July 1 |
| » Lost to Senators (34-35), 5-0 | Griffith Stadium (1-4) | 30-40 | |
| » Starters: Allen Russell vs Tom Zachary | Seventh | 12 out |
| Sunday, July 2 |
| » Defeated Senators (34-36), 2-1 | Griffith Stadium (2-4) | 31-40 | |
| » Starters: Alex Ferguson vs Walter Johnson | Seventh | 12 out |
| Tuesday, July 4 |
| » Defeated Senators (34-37), 4-3 | Griffith Stadium (3-4) | 32-40 | Won 2 |
| » Starters: Jack Quinn vs Eric Erickson | Seventh | 12 out |
| » Lost to Senators (35-37), 2-0 | Griffith Stadium (3-5) | 32-41 | |
| » Starters: Bill Piercy vs Ray Francis | Seventh | 12 out |
| Friday, July 7 |
| » Lost to Browns (46-30), 1-0 | Fenway Park (16-20) | 32-42 | Lost 2 |
| » Starters: Urban Shocker vs Herb Pennock | Sixth | 12 out |
| » Defeated Browns (46-31), 5-4 | Fenway Park (17-20) | 33-42 | |
| » Starters: Rasty Wright vs Alex Ferguson | Sixth | 12 out |
| Saturday, July 8 |
| » Defeated Browns (46-32), 2-1 | Fenway Park (18-20) | 34-42 | Won 2 |
| » Starters: Elam Vangilder vs Rip Collins | Seventh | 12 out |
| » Lost to Browns (47-32), 10-6 | Fenway Park (18-21) | 34-43 | |
| » Starters: Ray Kolp vs Bill Piercy | Seventh | 12 out |
| Monday, July 10 |
| » Lost to Browns (48-32), 5-4 | Fenway Park (18-22) | 34-44 | Lost 2 |
| » Starters: Dixie Davis vs Jack Quinn | Seventh | 12 out |
| » Defeated Browns (48-33), 4-3 | Fenway Park (19-22) | 35-44 | |
| » Starters: Dave Danforth vs Allen Russell | Seventh | 12 out |
| Tuesday, July 11 |
| » Lost to Indians (37-44), 2-0 | Fenway Park (19-23) | 35-45 | |
| » Starters: Guy Morton vs Alex Ferguson | Seventh | 12 out |
| Wednesday, July 12 |
| » Lost to Indians (38-44), 11-7 | Fenway Park (19-24) | 35-46 | Lost 2 |
| » Starters: Stan Coveleski vs Herb Pennock | Seventh | 13 out |
| Thursday, July 13 |
| » Lost to Indians (39-44), 4-2 | Fenway Park (19-25) | 35-47 | Lost 3 |
| » Starters: George Uhle vs Rip Collins | Eighth | 13½ out |
| Friday, July 14 |
| » Lost to Indians (40-44), 5-3 | Fenway Park (19-26) | 35-48 | Lost 4 |
| » Starters: Guy Morton vs Allen Russell | Eighth | 13½ out |
| Saturday, July 15 |
| » Lost to Tigers (44-42), 2-0 | Fenway Park (19-27) | 35-49 | Lost 5 |
| » Starters: Herman Pillette vs Alex Ferguson | Eighth | 13½ out |
| Monday, July 17 |
| » Lost to Tigers (45-42), 16-7 | Fenway Park (19-28) | 35-50 | Lost 6 |
| » Starters: Hooks Dauss vs Jack Quinn | Eighth | 14½ out |
| Tuesday, July 18 |
| » Defeated Tigers (45-43), 6-5 | Fenway Park (20-28) | 36-50 | |
| » Starters: Hooks Dauss vs Allen Russell | Eighth | 14 out |
| Wednesday, July 19 |
| » Lost to White Sox (46-41), 8-0 | Fenway Park (20-29) | 36-51 | |
| » Starters: Dixie Leverett vs Alex Ferguson | Eighth | 14 out |
| Thursday, July 20 |
| » Defeated White Sox (46-42), 3-2 | Fenway Park (21-29) | 37-51 | |
| » Starters: Red Faber vs Herb Pennock | Eighth | 14 out |
| Friday, July 21 |
| » Defeated White Sox (46-43), 8-7 | Fenway Park (22-29) | 38-51 | Won 2 |
| » Starters: Charlie Robertson vs Jack Quinn | Seventh | 14 out |
| Saturday, July 22 |
| » Lost to White Sox (47-43), 5-2 | Fenway Park (22-30) | 38-52 | |
| » Starters: Harry Courtney vs Allen Russell | Seventh | 15 out |
| Sunday, July 23 |
| » Lost to Yankees (53-41), 11-7 | Polo Grounds V (4-4) | 38-53 | Lost 2 |
| » Starters: Alex Ferguson vs Bullet Joe Bush | Seventh | 15 out |
| Tuesday, July 25 |
| » Lost to White Sox (49-44), 3-1 | Comiskey Park I (0-5) | 38-54 | Lost 3 |
| » Starters: Herb Pennock vs Ted Blankenship | Eighth | 16 out |
| Wednesday, July 26 |
| » Defeated White Sox (49-45), 3-1 | Comiskey Park I (1-5) | 39-54 | |
| » Starters: Jack Quinn vs Charlie Robertson | Seventh | 15 out |
| Thursday, July 27 |
| » Lost to White Sox (50-45), 4-3 | Comiskey Park I (1-6) | 39-55 | |
| » Starters: Benn Karr vs Dixie Leverett | Eighth | 15 out |
| Former Red Sox Nig Cuppy dies in Elkhart, IN at the age of 54. |
| Friday, July 28 |
| » Lost to White Sox (51-45), 4-3 | Comiskey Park I (1-7) | 39-56 | Lost 2 |
| » Starters: Alex Ferguson vs Red Faber | Eighth | 15½ out |
| Saturday, July 29 |
| » Lost to Browns (55-41), 4-1 | Sportsman's Park III (2-3) | 39-57 | Lost 3 |
| » Starters: Herb Pennock vs Urban Shocker | Eighth | 16½ out |
| Sunday, July 30 |
| » Lost to Browns (56-41), 4-1 | Sportsman's Park III (2-4) | 39-58 | Lost 4 |
| » Starters: Allen Russell vs Rasty Wright | Eighth | 17 out |
| Monday, July 31 |
| » Lost to Browns (57-41), 6-2 | Sportsman's Park III (2-5) | 39-59 | Lost 5 |
| » Starters: Jack Quinn vs Elam Vangilder | Eighth | 18 out |
| Tuesday, August 1 |
| » Lost to Browns (58-41), 5-2 | Sportsman's Park III (2-6) | 39-60 | Lost 6 |
| » Starters: Rip Collins vs Ray Kolp | Eighth | 19 out |
| Thursday, August 3 |
| » Lost to Tigers (55-47), 7-0 | Tiger Stadium (1-4) | 39-61 | Lost 7 |
| » Starters: Bill Piercy vs Herman Pillette | Eighth | 20 out |
| » Lost to Tigers (56-47), 7-4 | Tiger Stadium (1-5) | 39-62 | Lost 8 |
| » Starters: Allen Russell vs Red Oldham | Eighth | 20 out |
| Friday, August 4 |
| » Lost to Tigers (57-47), 2-0 | Tiger Stadium (1-6) | 39-63 | Lost 9 |
| » Starters: Herb Pennock vs Hooks Dauss | Eighth | 21 out |
| Saturday, August 5 |
| » Defeated Tigers (57-48), 8-4 | Tiger Stadium (2-6) | 40-63 | |
| » Starters: Rip Collins vs Red Oldham | Eighth | 21 out |
| Sunday, August 6 |
| » Lost to Indians (54-54), 3-2 | League Park II (2-3) | 40-64 | |
| » Starters: Jack Quinn vs Stan Coveleski | Eighth | 22 out |
| Monday, August 7 |
| » Lost to Indians (55-54), 7-0 | League Park II (2-4) | 40-65 | Lost 2 |
| » Starters: Alex Ferguson vs George Uhle | Eighth | 23 out |
| Tuesday, August 8 |
| » Defeated Indians (55-55), 15-6 | League Park II (3-4) | 41-65 | |
| » Starters: Benn Karr vs Guy Morton | Eighth | 22 out |
| Wednesday, August 9 |
| » Lost to Indians (56-55), 7-3 | League Park II (3-5) | 41-66 | |
| » Starters: Rip Collins vs Dan Boone | Eighth | 23 out |
| Friday, August 11 |
| » Lost to Senators (51-56), 5-4 | Fenway Park (22-31) | 41-67 | Lost 2 |
| » Starters: Walter Johnson vs Rip Collins | Eighth | 23½ out |
| Tuesday, August 15 |
| » Lost to White Sox (57-53), 19-11 | Fenway Park (22-32) | 41-68 | Lost 3 |
| » Starters: Charlie Robertson vs Jack Quinn | Eighth | 24 out |
| Wednesday, August 16 |
| » Defeated White Sox (57-54), 5-3 | Fenway Park (23-32) | 42-68 | |
| » Starters: Frank Mack vs Benn Karr | Eighth | 23½ out |
| Thursday, August 17 |
| » Defeated White Sox (57-55), 3-2 | Fenway Park (24-32) | 43-68 | Won 2 |
| » Starters: Red Faber vs Herb Pennock | Eighth | 23 out |
| » Defeated White Sox (57-56), 5-1 | Fenway Park (25-32) | 44-68 | Won 3 |
| » Starters: Dixie Leverett vs Alex Ferguson | Eighth | 23 out |
| Friday, August 18 |
| » Defeated Tigers (60-55), 8-0 | Fenway Park (26-32) | 45-68 | Won 4 |
| » Starters: Ole Olsen vs Rip Collins | Seventh | 22 out |
| Saturday, August 19 |
| » Lost to Tigers (61-55), 5-1 | Fenway Park (26-33) | 45-69 | |
| » Starters: Herman Pillette vs Allen Russell | Eighth | 23½ out |
| » Lost to Tigers (62-55), 1-0 | Fenway Park (26-34) | 45-70 | Lost 2 |
| » Starters: Howard Ehmke vs Benn Karr | Eighth | 23½ out |
| Monday, August 21 |
| » Lost to Tigers (63-55), 16-3 | Fenway Park (26-35) | 45-71 | Lost 3 |
| » Starters: Syl Johnson vs Rip Collins | Eighth | 24½ out |
| Tuesday, August 22 |
| » Lost to Browns (70-49), 9-4 | Fenway Park (26-36) | 45-72 | Lost 4 |
| » Starters: Urban Shocker vs Herb Pennock | Eighth | 24½ out |
| Wednesday, August 23 |
| » Lost to Browns (71-49), 6-3 | Fenway Park (26-37) | 45-73 | Lost 5 |
| » Starters: Rasty Wright vs Alex Ferguson | Eighth | 25 out |
| Future Red Sox George Kell is born in Swifton, AR. |
| Thursday, August 24 |
| » Lost to Browns (72-49), 13-2 | Fenway Park (26-38) | 45-74 | Lost 6 |
| » Starters: Ray Kolp vs Benn Karr | Eighth | 26 out |
| Friday, August 25 |
| » Defeated Indians (63-61), 9-0 | Fenway Park (27-38) | 46-74 | |
| » Starters: Dan Boone vs Jack Quinn | Eighth | 25½ out |
| Tuesday, August 29 |
| » Lost to Athletics (51-70), 6-5 | Shibe Park (4-4) | 46-75 | |
| » Starters: Benn Karr vs Eddie Rommel | Eighth | 27 out |
| Wednesday, August 30 |
| » Defeated Athletics (51-71), 6-5 | Shibe Park (5-4) | 47-75 | |
| » Starters: Herb Pennock vs Fred Heimach | Eighth | 27 out |
| Thursday, August 31 |
| » Defeated Athletics (51-72), 3-0 | Shibe Park (6-4) | 48-75 | Won 2 |
| » Starters: Rip Collins vs Slim Harriss | Eighth | 27 out |
| Friday, September 1 |
| » Lost to Athletics (52-72), 4-3 | Shibe Park (6-5) | 48-76 | |
| » Starters: Jack Quinn vs Eddie Rommel | Eighth | 27½ out |
| Saturday, September 2 |
| » Defeated Senators (58-69), 3-0 | Griffith Stadium (4-5) | 49-76 | |
| » Starters: Alex Ferguson vs Jim Brillheart | Eighth | 26½ out |
| » Defeated Senators (58-70), 1-0 | Griffith Stadium (5-5) | 50-76 | Won 2 |
| » Starters: Bill Piercy vs Walter Johnson | Eighth | 26½ out |
| Sunday, September 3 |
| » Lost to Senators (59-70), 10-3 | Griffith Stadium (5-6) | 50-77 | |
| » Starters: Curt Fullerton vs Tom Zachary | Eighth | 27 out |
| Tuesday, September 5 |
| » Defeated Yankees (78-52), 4-3 | Polo Grounds V (5-4) | 51-77 | |
| » Starters: Herb Pennock vs Waite Hoyt | Eighth | 25½ out |
| » Defeated Yankees (78-53), 6-5 | Polo Grounds V (6-4) | 52-77 | Won 2 |
| » Starters: Rip Collins vs Bullet Joe Bush | Eighth | 25½ out |
| Wednesday, September 6 |
| » Lost to Yankees (79-53), 9-2 | Polo Grounds V (6-5) | 52-78 | |
| » Starters: Jack Quinn vs Bob Shawkey | Eighth | 26½ out |
| Thursday, September 7 |
| » Lost to Athletics (55-74), 7-4 | Fenway Park (27-39) | 52-79 | Lost 2 |
| » Starters: Rollie Naylor vs Alex Ferguson | Eighth | 27½ out |
| » Lost to Athletics (56-74), 3-0 | Fenway Park (27-40) | 52-80 | Lost 3 |
| » Starters: Eddie Rommel vs Bill Piercy | Eighth | 27½ out |
| Friday, September 8 |
| » Defeated Athletics (56-75), 2-1 | Fenway Park (28-40) | 53-80 | |
| » Starters: Bob Hasty vs Rip Collins | Eighth | 27 out |
| Saturday, September 9 |
| » Lost to Athletics (57-75), 3-1 | Fenway Park (28-41) | 53-81 | |
| » Starters: Curly Ogden vs Herb Pennock | Eighth | 27½ out |
| » Defeated Athletics (57-76), 3-2 | Fenway Park (29-41) | 54-81 | |
| » Starters: Eddie Rommel vs Jack Quinn | Eighth | 27½ out |
| Sunday, September 10 |
| » Defeated Senators (60-74), 6-1 | Griffith Stadium (6-6) | 55-81 | Won 2 |
| » Starters: Alex Ferguson vs Tom Zachary | Eighth | 28 out |
| Monday, September 11 |
| » Lost to Senators (61-74), 12-3 | Griffith Stadium (6-7) | 55-82 | |
| » Starters: Bill Piercy vs Jim Brillheart | Eighth | 29 out |
| Wednesday, September 13 |
| » Defeated Browns (84-56), 3-1 | Sportsman's Park III (3-6) | 56-82 | |
| » Starters: Rip Collins vs Urban Shocker | Eighth | 28½ out |
| Thursday, September 14 |
| » Lost to Browns (85-56), 5-3 | Sportsman's Park III (3-7) | 56-83 | |
| » Starters: Jack Quinn vs Dixie Davis | Eighth | 29½ out |
| Friday, September 15 |
| » Lost to Browns (86-56), 7-1 | Sportsman's Park III (3-8) | 56-84 | Lost 2 |
| » Starters: Herb Pennock vs Elam Vangilder | Eighth | 29½ out |
| Saturday, September 16 |
| » Lost to White Sox (72-71), 9-2 | Comiskey Park I (1-8) | 56-85 | Lost 3 |
| » Starters: Benn Karr vs Red Faber | Eighth | 30½ out |
| Sunday, September 17 |
| » Defeated White Sox (72-72), 3-2 | Comiskey Park I (2-8) | 57-85 | |
| » Starters: Rip Collins vs Charlie Robertson | Eighth | 29½ out |
| Monday, September 18 |
| » Lost to White Sox (73-72), 7-0 | Comiskey Park I (2-9) | 57-86 | |
| » Starters: Jack Quinn vs Dixie Leverett | Eighth | 30½ out |
| Former Red Sox Jake Stahl dies in Monrovia, CA at the age of 44. |
| Tuesday, September 19 |
| » Lost to Indians (72-73), 7-4 | League Park II (3-6) | 57-87 | Lost 2 |
| » Starters: Herb Pennock vs Dewey Metivier | Eighth | 32 out |
| » Lost to Indians (73-73), 3-2 | League Park II (3-7) | 57-88 | Lost 3 |
| » Starters: Alex Ferguson vs George Winn | Eighth | 32 out |
| Wednesday, September 20 |
| » Lost to Indians (74-73), 5-2 | League Park II (3-8) | 57-89 | Lost 4 |
| » Starters: Rip Collins vs George Uhle | Eighth | 33½ out |
| » Lost to Indians (75-73), 5-4 | League Park II (3-9) | 57-90 | Lost 5 |
| » Starters: Bill Piercy vs Phil Bedgood | Eighth | 33½ out |
| Thursday, September 21 |
| » Defeated Indians (75-74), 15-5 | League Park II (4-9) | 58-90 | |
| » Starters: Jack Quinn vs John Middleton | Eighth | 33½ out |
| Friday, September 22 |
| » Lost to Tigers (78-72), 5-3 | Tiger Stadium (2-7) | 58-91 | |
| » Starters: Alex Ferguson vs Herman Pillette | Eighth | 34½ out |
| Saturday, September 23 |
| » Defeated Tigers (78-73), 6-4 | Tiger Stadium (3-7) | 59-91 | |
| » Starters: Rip Collins vs Howard Ehmke | Eighth | 34½ out |
| Sunday, September 24 |
| » Lost to Tigers (79-73), 7-2 | Tiger Stadium (3-8) | 59-92 | |
| » Starters: Herb Pennock vs Herman Pillette | Eighth | 34½ out |
| Thursday, September 28 |
| » Defeated Yankees (93-58), 3-1 | Fenway Park (30-41) | 60-92 | |
| » Starters: Bullet Joe Bush vs Rip Collins | Eighth | 33½ out |
| Friday, September 29 |
| » Defeated Yankees (93-59), 1-0 | Fenway Park (31-41) | 61-92 | Won 2 |
| » Starters: Bob Shawkey vs Jack Quinn | Eighth | 32½ out |
| Saturday, September 30 |
| » Lost to Yankees (94-59), 3-1 | Fenway Park (31-42) | 61-93 | |
| » Starters: Waite Hoyt vs Alex Ferguson | Seventh | 33½ out |
| Saturday, October 7 |
| Future Red Sox Grady Hatton is born in Beaumont, TX. |
| Friday, November 10 |
| Future Red Sox Johnny Lipon is born in Martins Ferry, OH. |
Game information provided by Retrosheet (www.retrosheet.org) |