| Friday, February 3 |
| Future Indian Jim Dyck is born in Omaha, NE. |
| Saturday, February 18 |
| Future Indian Joe Tipton is born in McCaysville, GA. |
| Wednesday, April 12 |
| » Defeated Tigers (0-1), 7-4 | League Park II (1-0) | 1-0 | |
| » Starters: Red Oldham vs Guy Morton | First | -- |
| » Major-league debuts: Ole Olsen and Topper Rigney (Tigers) |
| Future Indian Bill Wight is born in Rio Vista, CA. |
| Thursday, April 13 |
| » Defeated Tigers (0-2), 8-3 | League Park II (2-0) | 2-0 | Won 2 |
| » Starters: Howard Ehmke vs George Uhle | First | -- |
| Saturday, April 15 |
| » Defeated Tigers (0-3), 11-4 | League Park II (3-0) | 3-0 | Won 3 |
| » Starters: Carl Holling vs Jim Bagby | First | -- |
| » Major-league debuts: John Mohardt and Lil Stoner (Tigers) |
| Sunday, April 16 |
| » Defeated Browns (3-1), 3-0 | League Park II (4-0) | 4-0 | Won 4 |
| » Starters: Urban Shocker vs Duster Mails | First | -- |
| Monday, April 17 |
| » Major-league debuts: Jim Brillheart (Senators) |
| Tuesday, April 18 |
| » Defeated Browns (3-2), 17-2 | League Park II (5-0) | 5-0 | Won 5 |
| » Starters: Ray Kolp vs George Uhle | First | -- |
| Wednesday, April 19 |
| » Lost to Browns (4-2), 15-1 | League Park II (5-1) | 5-1 | |
| » Starters: Elam Vangilder vs Stan Coveleski | First | -- |
| » Major-league debuts: Nellie Pott (Indians) |
| Thursday, April 20 |
| » Defeated Tigers (0-6), 5-4 | Tiger Stadium (1-0) | 6-1 | |
| » Starters: Jim Bagby vs Howard Ehmke | First | -- |
| Friday, April 21 |
| » Lost to Tigers (1-6), 15-7 | Tiger Stadium (1-1) | 6-2 | |
| » Starters: Duster Mails vs Lil Stoner | First | -- |
| Saturday, April 22 |
| » Lost to Tigers (2-6), 3-2 | Tiger Stadium (1-2) | 6-3 | Lost 2 |
| » Starters: George Uhle vs Ole Olsen | Second | 1 out |
| Sunday, April 23 |
| » Lost to Tigers (3-6), 4-3 | Tiger Stadium (1-3) | 6-4 | Lost 3 |
| » Starters: Stan Coveleski vs Herman Pillette | Second | 2 out |
| Monday, April 24 |
| » Defeated White Sox (4-6), 6-5 | League Park II (6-1) | 7-4 | |
| » Starters: Red Faber vs Duster Mails | Second | 2 out |
| Wednesday, April 26 |
| » Lost to White Sox (5-6), 7-3 | League Park II (6-2) | 7-5 | |
| » Starters: Charlie Robertson vs Jim Bagby | Third | 2½ out |
| Future Indian Sam Dente is born in Harrison, NJ. |
| Thursday, April 27 |
| » Tied White Sox, 6-6 | League Park II (6-2) | 7-5 | |
| » Starters: Shovel Hodge vs George Uhle | Third | 2½ out |
| Friday, April 28 |
| » Lost to Browns (9-5), 3-2 | Sportsman's Park III (0-1) | 7-6 | Lost 2 |
| » Starters: Duster Mails vs Urban Shocker | Third | 3½ out |
| Saturday, April 29 |
| » Lost to Browns (10-5), 6-5 | Sportsman's Park III (0-2) | 7-7 | Lost 3 |
| » Starters: Stan Coveleski vs Elam Vangilder | Fourth | 3½ out |
| Sunday, April 30 |
| » Lost to Browns (11-5), 11-9 | Sportsman's Park III (0-3) | 7-8 | Lost 4 |
| » Starters: Jim Bagby vs Dixie Davis | Fourth | 3½ out |
| Monday, May 1 |
| » Lost to Browns (12-5), 13-2 | Sportsman's Park III (0-4) | 7-9 | Lost 5 |
| » Starters: George Uhle vs Ray Kolp | Sixth | 4½ out |
| » Major-league debuts: Jim Lindsey (Indians) |
| Tuesday, May 2 |
| » Defeated White Sox (9-7), 10-6 | Comiskey Park I (1-0) | 8-9 | |
| » Starters: Stan Coveleski vs John Russell | Third | 3½ out |
| Thursday, May 4 |
| » Defeated White Sox (9-8), 5-3 | Comiskey Park I (2-0) | 9-9 | Won 2 |
| » Starters: Duster Mails vs Red Faber | Third | 2½ out |
| Friday, May 5 |
| » Defeated White Sox (9-9), 6-3 | Comiskey Park I (3-0) | 10-9 | Won 3 |
| » Starters: Allen Sothoron vs Charlie Robertson | Second | 2½ out |
| Saturday, May 6 |
| » Defeated Browns (13-8), 6-2 | League Park II (7-2) | 11-9 | Won 4 |
| » Starters: Urban Shocker vs Stan Coveleski | Third | 2½ out |
| Sunday, May 7 |
| » Lost to Browns (14-8), 10-7 | League Park II (7-3) | 11-10 | |
| » Starters: Ray Kolp vs Duster Mails | Third | 3½ out |
| Monday, May 8 |
| » Defeated Athletics (9-12), 14-4 | Shibe Park (1-0) | 12-10 | |
| » Starters: George Uhle vs Bob Hasty | Third | 3½ out |
| Tuesday, May 9 |
| » Lost to Athletics (10-12), 15-4 | Shibe Park (1-1) | 12-11 | |
| » Starters: Stan Coveleski vs Eddie Rommel | Third | 4½ out |
| Wednesday, May 10 |
| » Lost to Athletics (11-12), 7-6 | Shibe Park (1-2) | 12-12 | Lost 2 |
| » Starters: Allen Sothoron vs Fred Heimach | Third | 4½ out |
| Thursday, May 11 |
| » Defeated Athletics (11-13), 5-4 | Shibe Park (2-2) | 13-12 | |
| » Starters: Jim Lindsey vs Fred Heimach | Third | 4½ out |
| Friday, May 12 |
| » Lost to Senators (10-17), 5-4 | Griffith Stadium (0-1) | 13-13 | |
| » Starters: Stan Coveleski vs Eric Erickson | Third | 5½ out |
| Saturday, May 13 |
| » Defeated Senators (10-18), 5-4 | Griffith Stadium (1-1) | 14-13 | |
| » Starters: George Uhle vs Ray Francis | Third | 4½ out |
| » Major-league debuts: Ed Goebel (Senators) |
| Sunday, May 14 |
| » Lost to Senators (11-18), 4-3 | Griffith Stadium (1-2) | 14-14 | |
| » Starters: James Edwards vs George Mogridge | Third | 4½ out |
| » Major-league debuts: Jim Joe Edwards (Indians) |
| Monday, May 15 |
| » Lost to Senators (12-18), 3-2 | Griffith Stadium (1-3) | 14-15 | Lost 2 |
| » Starters: Jim Bagby vs Walter Johnson | Third | 4½ out |
| Tuesday, May 16 |
| » Lost to Yankees (20-11), 3-0 | Polo Grounds V (0-1) | 14-16 | Lost 3 |
| » Starters: Stan Coveleski vs Waite Hoyt | Fifth | 5½ out |
| Wednesday, May 17 |
| » Lost to Yankees (21-11), 6-4 | Polo Grounds V (0-2) | 14-17 | Lost 4 |
| » Starters: George Uhle vs Bob Shawkey | Sixth | 6½ out |
| Friday, May 19 |
| » Lost to Yankees (22-11), 12-4 | Polo Grounds V (0-3) | 14-18 | Lost 5 |
| » Starters: Allen Sothoron vs Carl Mays | Sixth | 7½ out |
| Saturday, May 20 |
| » Defeated Red Sox (13-15), 5-2 | Fenway Park (1-0) | 15-18 | |
| » Starters: Stan Coveleski vs Bill Piercy | Sixth | 6½ out |
| Monday, May 22 |
| » Defeated Red Sox (13-16), 7-1 | Fenway Park (2-0) | 16-18 | Won 2 |
| » Starters: Guy Morton vs Jack Quinn | Fourth | 7 out |
| Tuesday, May 23 |
| » Defeated Red Sox (13-17), 5-3 | Fenway Park (3-0) | 17-18 | Won 3 |
| » Starters: George Uhle vs Herb Pennock | Fourth | 6 out |
| Wednesday, May 24 |
| » Lost to Red Sox (14-17), 6-2 | Fenway Park (3-1) | 17-19 | |
| » Starters: Jim Bagby vs Rip Collins | Fifth | 6 out |
| Thursday, May 25 |
| » Lost to Tigers (18-17), 7-3 | Tiger Stadium (1-4) | 17-20 | Lost 2 |
| » Starters: Stan Coveleski vs Herman Pillette | Fifth | 7 out |
| Friday, May 26 |
| » Defeated Tigers (18-18), 8-3 | Tiger Stadium (2-4) | 18-20 | |
| » Starters: Guy Morton vs Lil Stoner | Fourth | 6 out |
| Saturday, May 27 |
| » Defeated Tigers (18-19), 5-3 | Tiger Stadium (3-4) | 19-20 | Won 2 |
| » Starters: George Uhle vs Hooks Dauss | Fourth | 6 out |
| Sunday, May 28 |
| » Lost to Tigers (19-19), 7-5 | Tiger Stadium (3-5) | 19-21 | |
| » Starters: Jim Bagby vs Herman Pillette | Fifth | 6 out |
| Monday, May 29 |
| » Defeated White Sox (16-23), 8-5 | League Park II (8-3) | 20-21 | |
| » Starters: Ferdie Schupp vs Stan Coveleski | Third | 6 out |
| Tuesday, May 30 |
| » Lost to White Sox (17-23), 4-0 | League Park II (8-4) | 20-22 | |
| » Starters: Dixie Leverett vs Guy Morton | Sixth | 7 out |
| » Lost to White Sox (18-23), 7-6 | League Park II (8-5) | 20-23 | Lost 2 |
| » Starters: Harry Courtney vs Allen Sothoron | Sixth | 7 out |
| Future Indian Bob Hooper is born in Leamington, ON. |
| Wednesday, May 31 |
| » Lost to White Sox (19-23), 8-4 | League Park II (8-6) | 20-24 | Lost 3 |
| » Starters: Charlie Robertson vs Jim Lindsey | Sixth | 7½ out |
| Thursday, June 1 |
| » Defeated Tigers (20-23), 5-2 | League Park II (9-6) | 21-24 | |
| » Starters: Ole Olsen vs George Uhle | Fifth | 7½ out |
| Friday, June 2 |
| » Defeated Tigers (20-24), 9-4 | League Park II (10-6) | 22-24 | Won 2 |
| » Starters: Herman Pillette vs Stan Coveleski | Fifth | 7 out |
| Saturday, June 3 |
| » Defeated Tigers (20-25), 5-4 | League Park II (11-6) | 23-24 | Won 3 |
| » Starters: Howard Ehmke vs Guy Morton | Third | 6 out |
| Sunday, June 4 |
| » Defeated Tigers (20-26), 14-6 | League Park II (12-6) | 24-24 | Won 4 |
| » Starters: Hooks Dauss vs George Uhle | Third | 6 out |
| Tuesday, June 6 |
| » Lost to Senators (24-25), 3-0 | League Park II (12-7) | 24-25 | |
| » Starters: Eric Erickson vs Stan Coveleski | Third | 7 out |
| Wednesday, June 7 |
| » Lost to Senators (25-25), 9-8 | League Park II (12-8) | 24-26 | Lost 2 |
| » Starters: Ray Francis vs Guy Morton | Fourth | 8 out |
| Thursday, June 8 |
| » Lost to Senators (26-25), 6-1 | League Park II (12-9) | 24-27 | Lost 3 |
| » Starters: Tom Zachary vs George Uhle | Fourth | 9 out |
| Saturday, June 10 |
| » Lost to Athletics (21-24), 3-0 | League Park II (12-10) | 24-28 | Lost 4 |
| » Starters: Eddie Rommel vs Stan Coveleski | Sixth | 9½ out |
| Sunday, June 11 |
| » Defeated Athletics (21-25), 9-8 | League Park II (13-10) | 25-28 | |
| » Starters: Bob Hasty vs Jim Bagby | Fifth | 9½ out |
| Monday, June 12 |
| » Defeated Athletics (21-26), 11-3 | League Park II (14-10) | 26-28 | Won 2 |
| » Starters: Rollie Naylor vs George Uhle | Fourth | 8½ out |
| Wednesday, June 14 |
| » Defeated Red Sox (21-31), 3-0 | League Park II (15-10) | 27-28 | Won 3 |
| » Starters: Rip Collins vs Stan Coveleski | Third | 7 out |
| Thursday, June 15 |
| » Lost to Red Sox (22-31), 8-3 | League Park II (15-11) | 27-29 | |
| » Starters: Jack Quinn vs Duster Mails | Fourth | 7 out |
| Friday, June 16 |
| » Lost to Red Sox (23-31), 8-6 | League Park II (15-12) | 27-30 | Lost 2 |
| » Starters: Alex Ferguson vs George Uhle | Fourth | 7½ out |
| Saturday, June 17 |
| » Defeated Red Sox (23-32), 5-4 | League Park II (16-12) | 28-30 | |
| » Starters: Rip Collins vs Dave Keefe | Fourth | 6½ out |
| Sunday, June 18 |
| » Defeated Yankees (35-26), 9-2 | League Park II (17-12) | 29-30 | Won 2 |
| » Starters: Waite Hoyt vs Stan Coveleski | Fourth | 6½ out |
| Monday, June 19 |
| » Defeated Yankees (35-27), 4-2 | League Park II (18-12) | 30-30 | Won 3 |
| » Starters: Carl Mays vs Duster Mails | Fourth | 6½ out |
| Tuesday, June 20 |
| » Lost to Yankees (36-27), 6-5 | League Park II (18-13) | 30-31 | |
| » Starters: Bullet Joe Bush vs George Uhle | Fourth | 7½ out |
| Wednesday, June 21 |
| » Lost to Yankees (37-27), 7-3 | League Park II (18-14) | 30-32 | Lost 2 |
| » Starters: Bob Shawkey vs James Edwards | Fourth | 7½ out |
| Thursday, June 22 |
| » Lost to White Sox (31-32), 3-0 | Comiskey Park I (3-1) | 30-33 | Lost 3 |
| » Starters: Stan Coveleski vs Dixie Leverett | Fifth | 7½ out |
| Friday, June 23 |
| » Lost to White Sox (32-32), 6-5 | Comiskey Park I (3-2) | 30-34 | Lost 4 |
| » Starters: Duster Mails vs Ferdie Schupp | Sixth | 7½ out |
| » Major-league debuts: Bill Doran (Indians) |
| Saturday, June 24 |
| » Lost to White Sox (33-32), 6-4 | Comiskey Park I (3-3) | 30-35 | Lost 5 |
| » Starters: Guy Morton vs Red Faber | Sixth | 8½ out |
| Sunday, June 25 |
| » Lost to White Sox (34-32), 4-3 | Comiskey Park I (3-4) | 30-36 | Lost 6 |
| » Starters: Jim Lindsey vs Charlie Robertson | Sixth | 9½ out |
| Monday, June 26 |
| » Defeated Browns (40-28), 6-0 | League Park II (19-14) | 31-36 | |
| » Starters: Hub Pruett vs Stan Coveleski | Sixth | 8½ out |
| Tuesday, June 27 |
| » Defeated Browns (40-29), 9-7 | League Park II (20-14) | 32-36 | Won 2 |
| » Starters: Rasty Wright vs Duster Mails | Fifth | 7½ out |
| Wednesday, June 28 |
| » Lost to Browns (41-29), 9-0 | League Park II (20-15) | 32-37 | |
| » Starters: Ray Kolp vs James Edwards | Sixth | 8½ out |
| Friday, June 30 |
| » Lost to Browns (42-29), 10-3 | Sportsman's Park III (0-5) | 32-38 | Lost 2 |
| » Starters: Stan Coveleski vs Elam Vangilder | Sixth | 9½ out |
| Saturday, July 1 |
| » Lost to Browns (43-29), 4-3 | Sportsman's Park III (0-6) | 32-39 | Lost 3 |
| » Starters: George Uhle vs Rasty Wright | Sixth | 10½ out |
| Sunday, July 2 |
| » Lost to Browns (44-29), 9-5 | Sportsman's Park III (0-7) | 32-40 | Lost 4 |
| » Starters: Duster Mails vs Ray Kolp | Sixth | 11½ out |
| Tuesday, July 4 |
| » Defeated Tigers (37-36), 4-2 | Tiger Stadium (4-5) | 33-40 | |
| » Starters: Guy Morton vs Hooks Dauss | Sixth | 10½ out |
| » Defeated Tigers (37-37), 11-4 | Tiger Stadium (5-5) | 34-40 | Won 2 |
| » Starters: Stan Coveleski vs Red Oldham | Sixth | 10½ out |
| Wednesday, July 5 |
| » Lost to Tigers (38-37), 6-5 | Tiger Stadium (5-6) | 34-41 | |
| » Starters: George Uhle vs Herman Pillette | Sixth | 11 out |
| Thursday, July 6 |
| » Lost to Yankees (45-33), 10-3 | Polo Grounds V (0-4) | 34-42 | Lost 2 |
| » Starters: Duster Mails vs Bullet Joe Bush | Sixth | 12 out |
| » Lost to Yankees (46-33), 11-3 | Polo Grounds V (0-5) | 34-43 | Lost 3 |
| » Starters: Jim Lindsey vs Bob Shawkey | Sixth | 12 out |
| » Major-league debuts: Joe Shaute (Indians) |
| Friday, July 7 |
| » Lost to Yankees (47-33), 1-0 | Polo Grounds V (0-6) | 34-44 | Lost 4 |
| » Starters: Guy Morton vs Waite Hoyt | Seventh | 12½ out |
| Saturday, July 8 |
| » Defeated Yankees (47-34), 3-1 | Polo Grounds V (1-6) | 35-44 | |
| » Starters: Stan Coveleski vs Carl Mays | Sixth | 12 out |
| Sunday, July 9 |
| » Defeated Yankees (47-35), 9-7 | Polo Grounds V (2-6) | 36-44 | Won 2 |
| » Starters: George Uhle vs Sad Sam Jones | Sixth | 11½ out |
| Tuesday, July 11 |
| » Defeated Red Sox (35-45), 2-0 | Fenway Park (4-1) | 37-44 | Won 3 |
| » Starters: Guy Morton vs Alex Ferguson | Sixth | 10½ out |
| Wednesday, July 12 |
| » Defeated Red Sox (35-46), 11-7 | Fenway Park (5-1) | 38-44 | Won 4 |
| » Starters: Stan Coveleski vs Herb Pennock | Sixth | 10½ out |
| Thursday, July 13 |
| » Defeated Red Sox (35-47), 4-2 | Fenway Park (6-1) | 39-44 | Won 5 |
| » Starters: George Uhle vs Rip Collins | Sixth | 10 out |
| Friday, July 14 |
| » Defeated Red Sox (35-48), 5-3 | Fenway Park (7-1) | 40-44 | Won 6 |
| » Starters: Guy Morton vs Allen Russell | Sixth | 9 out |
| Saturday, July 15 |
| » Defeated Athletics (34-45), 2-0 | Shibe Park (3-2) | 41-44 | Won 7 |
| » Starters: Stan Coveleski vs Eddie Rommel | Sixth | 8 out |
| Monday, July 17 |
| » Defeated Athletics (34-46), 5-0 | Shibe Park (4-2) | 42-44 | Won 8 |
| » Starters: George Uhle vs Slim Harriss | Fifth | 8 out |
| Tuesday, July 18 |
| » Defeated Athletics (34-47), 6-3 | Shibe Park (5-2) | 43-44 | Won 9 |
| » Starters: Guy Morton vs Bob Hasty | Fifth | 7½ out |
| Wednesday, July 19 |
| » Defeated Senators (40-44), 4-1 | Griffith Stadium (2-3) | 44-44 | Won 10 |
| » Starters: Stan Coveleski vs Jim Brillheart | Fifth | 6½ out |
| Thursday, July 20 |
| » Defeated Senators (40-45), 8-2 | Griffith Stadium (3-3) | 45-44 | Won 11 |
| » Starters: George Uhle vs Eric Erickson | Fifth | 6½ out |
| Friday, July 21 |
| » Defeated Senators (40-46), 1-0 | Griffith Stadium (4-3) | 46-44 | Won 12 |
| » Starters: Guy Morton vs Walter Johnson | Fourth | 6½ out |
| Saturday, July 22 |
| » Lost to Senators (41-46), 4-2 | Griffith Stadium (4-4) | 46-45 | |
| » Starters: Duster Mails vs George Mogridge | Fifth | 7½ out |
| Sunday, July 23 |
| » Lost to White Sox (48-43), 10-6 | League Park II (20-16) | 46-46 | Lost 2 |
| » Starters: Dixie Leverett vs George Uhle | Fifth | 7½ out |
| Monday, July 24 |
| » Defeated White Sox (48-44), 5-2 | League Park II (21-16) | 47-46 | |
| » Starters: Red Faber vs Stan Coveleski | Fifth | 7 out |
| Tuesday, July 25 |
| » Defeated Athletics (36-52), 4-0 | League Park II (22-16) | 48-46 | Won 2 |
| » Starters: Eddie Rommel vs Guy Morton | Fifth | 7½ out |
| » Lost to Athletics (37-52), 11-4 | League Park II (22-17) | 48-47 | |
| » Starters: Bob Hasty vs Guy Morton | Fifth | 7½ out |
| Wednesday, July 26 |
| » Defeated Athletics (37-53), 2-0 | League Park II (23-17) | 49-47 | |
| » Starters: Otto Rettig vs George Uhle | Fifth | 6½ out |
| Future Indian Hoyt Wilhelm is born in Huntersville, NC. |
| Thursday, July 27 |
| » Lost to Athletics (38-53), 11-2 | League Park II (23-18) | 49-48 | |
| » Starters: Rollie Naylor vs Stan Coveleski | Fifth | 6½ out |
| Friday, July 28 |
| » Lost to Athletics (39-53), 12-3 | League Park II (23-19) | 49-49 | Lost 2 |
| » Starters: Slim Harriss vs Guy Morton | Fifth | 7 out |
| Saturday, July 29 |
| » Lost to Senators (45-49), 18-6 | League Park II (23-20) | 49-50 | Lost 3 |
| » Starters: Walter Johnson vs George Uhle | Fifth | 7½ out |
| » Defeated Senators (45-50), 8-7 | League Park II (24-20) | 50-50 | |
| » Starters: Jim Brillheart vs Stan Coveleski | Fifth | 7½ out |
| Sunday, July 30 |
| » Defeated Senators (45-51), 11-3 | League Park II (25-20) | 51-50 | Won 2 |
| » Starters: Eric Erickson vs George Uhle | Fifth | 7 out |
| Monday, July 31 |
| » Defeated Senators (45-52), 14-5 | League Park II (26-20) | 52-50 | Won 3 |
| » Starters: Tom Zachary vs Guy Morton | Fifth | 7 out |
| Tuesday, August 1 |
| » Defeated Senators (45-53), 17-3 | League Park II (27-20) | 53-50 | Won 4 |
| » Starters: Ray Francis vs Jim Bagby | Fifth | 7 out |
| Wednesday, August 2 |
| » Lost to Yankees (58-44), 5-1 | League Park II (27-21) | 53-51 | |
| » Starters: Bullet Joe Bush vs Stan Coveleski | Fifth | 7 out |
| Thursday, August 3 |
| » Lost to Yankees (59-44), 10-9 | League Park II (27-22) | 53-52 | Lost 2 |
| » Starters: Carl Mays vs George Uhle | Fifth | 8 out |
| Friday, August 4 |
| » Lost to Yankees (60-44), 7-5 | League Park II (27-23) | 53-53 | Lost 3 |
| » Starters: George Murray vs Guy Morton | Fifth | 9 out |
| Saturday, August 5 |
| » Lost to Yankees (61-44), 7-1 | League Park II (27-24) | 53-54 | Lost 4 |
| » Starters: Bob Shawkey vs Jim Bagby | Fifth | 10 out |
| Sunday, August 6 |
| » Defeated Red Sox (40-64), 3-2 | League Park II (28-24) | 54-54 | |
| » Starters: Jack Quinn vs Stan Coveleski | Fifth | 10 out |
| Monday, August 7 |
| » Defeated Red Sox (40-65), 7-0 | League Park II (29-24) | 55-54 | Won 2 |
| » Starters: Alex Ferguson vs George Uhle | Fifth | 10 out |
| Tuesday, August 8 |
| » Lost to Red Sox (41-65), 15-6 | League Park II (29-25) | 55-55 | |
| » Starters: Benn Karr vs Guy Morton | Fifth | 10 out |
| Wednesday, August 9 |
| » Defeated Red Sox (41-66), 7-3 | League Park II (30-25) | 56-55 | |
| » Starters: Rip Collins vs Dan Boone | Fifth | 10 out |
| Saturday, August 12 |
| » Lost to Tigers (59-51), 10-5 | League Park II (30-26) | 56-56 | |
| » Starters: Herman Pillette vs Stan Coveleski | Fifth | 11 out |
| Sunday, August 13 |
| » Defeated Tigers (59-52), 3-2 | League Park II (31-26) | 57-56 | |
| » Starters: Hooks Dauss vs George Uhle | Fifth | 10 out |
| Tuesday, August 15 |
| » Defeated Athletics (42-64), 11-4 | Shibe Park (6-2) | 58-56 | Won 2 |
| » Starters: Guy Morton vs Rollie Naylor | Fifth | 10 out |
| » Lost to Athletics (43-64), 7-4 | Shibe Park (6-3) | 58-57 | |
| » Starters: Dan Boone vs Eddie Rommel | Fifth | 10 out |
| Wednesday, August 16 |
| » Lost to Athletics (44-64), 10-9 | Shibe Park (6-4) | 58-58 | Lost 2 |
| » Starters: Stan Coveleski vs Slim Harriss | Fifth | 10½ out |
| Future Indian Gene Woodling is born in Akron, OH. |
| Thursday, August 17 |
| » Lost to Athletics (45-64), 8-1 | Shibe Park (6-5) | 58-59 | Lost 3 |
| » Starters: George Uhle vs Bob Hasty | Fifth | 11½ out |
| Friday, August 18 |
| » Defeated Senators (54-60), 7-5 | Griffith Stadium (5-4) | 59-59 | |
| » Starters: Guy Morton vs Eric Erickson | Fourth | 10½ out |
| Saturday, August 19 |
| » Defeated Senators (54-61), 3-1 | Griffith Stadium (6-4) | 60-59 | Won 2 |
| » Starters: Stan Coveleski vs Tom Zachary | Fourth | 10½ out |
| Sunday, August 20 |
| » Defeated Senators (54-62), 2-0 | Griffith Stadium (7-4) | 61-59 | Won 3 |
| » Starters: Dan Boone vs Walter Johnson | Fourth | 10½ out |
| Tuesday, August 22 |
| » Defeated Yankees (70-48), 6-2 | Polo Grounds V (3-6) | 62-59 | Won 4 |
| » Starters: George Uhle vs Bullet Joe Bush | Fourth | 9½ out |
| Wednesday, August 23 |
| » Defeated Yankees (70-49), 4-1 | Polo Grounds V (4-6) | 63-59 | Won 5 |
| » Starters: Stan Coveleski vs Bob Shawkey | Fourth | 9 out |
| Thursday, August 24 |
| » Lost to Yankees (71-49), 7-3 | Polo Grounds V (4-7) | 63-60 | |
| » Starters: Guy Morton vs Sad Sam Jones | Fourth | 10 out |
| Friday, August 25 |
| » Lost to Red Sox (46-74), 9-0 | Fenway Park (7-2) | 63-61 | Lost 2 |
| » Starters: Dan Boone vs Jack Quinn | Fourth | 10½ out |
| Tuesday, August 29 |
| » Lost to Browns (74-52), 6-3 | League Park II (31-27) | 63-62 | Lost 3 |
| » Starters: Ray Kolp vs George Uhle | Fourth | 12 out |
| Wednesday, August 30 |
| » Lost to Browns (75-52), 11-3 | League Park II (31-28) | 63-63 | Lost 4 |
| » Starters: Rasty Wright vs Dan Boone | Fourth | 13 out |
| Thursday, August 31 |
| » Defeated Browns (75-53), 7-6 | League Park II (32-28) | 64-63 | |
| » Starters: Dixie Davis vs George Winn | Fourth | 13 out |
| Friday, September 1 |
| » Lost to White Sox (64-63), 2-0 | League Park II (32-29) | 64-64 | |
| » Starters: Charlie Robertson vs George Uhle | Fifth | 13½ out |
| Saturday, September 2 |
| » Defeated White Sox (64-64), 2-0 | League Park II (33-29) | 65-64 | |
| » Starters: Dixie Leverett vs Dan Boone | Fourth | 13 out |
| Sunday, September 3 |
| » Defeated White Sox (64-65), 5-0 | League Park II (34-29) | 66-64 | Won 2 |
| » Starters: Ted Blankenship vs George Uhle | Fourth | 12½ out |
| Future Indian Morrie Martin is born in Dixon, MO. |
| Monday, September 4 |
| » Lost to Browns (78-54), 10-3 | Sportsman's Park III (0-8) | 66-65 | |
| » Starters: Jim Lindsey vs Urban Shocker | Fifth | 13½ out |
| » Lost to Browns (79-54), 12-1 | Sportsman's Park III (0-9) | 66-66 | Lost 2 |
| » Starters: George Winn vs Elam Vangilder | Fifth | 13½ out |
| Tuesday, September 5 |
| » Lost to Browns (80-54), 10-9 | Sportsman's Park III (0-10) | 66-67 | Lost 3 |
| » Starters: Dan Boone vs Ray Kolp | Fifth | 13½ out |
| » Major-league debuts: Pat McNulty (Indians) |
| Wednesday, September 6 |
| » Lost to Browns (81-54), 11-3 | Sportsman's Park III (0-11) | 66-68 | Lost 4 |
| » Starters: George Uhle vs Dixie Davis | Fifth | 14½ out |
| Thursday, September 7 |
| » Lost to White Sox (68-67), 9-8 | Comiskey Park I (3-5) | 66-69 | Lost 5 |
| » Starters: Guy Morton vs Red Faber | Fifth | 15 out |
| Friday, September 8 |
| » Lost to White Sox (69-67), 7-2 | Comiskey Park I (3-6) | 66-70 | Lost 6 |
| » Starters: Dan Boone vs Dixie Leverett | Fifth | 15½ out |
| Saturday, September 9 |
| » Defeated White Sox (69-68), 3-2 | Comiskey Park I (4-6) | 67-70 | |
| » Starters: James Edwards vs Ted Blankenship | Fifth | 15½ out |
| Tuesday, September 12 |
| » Defeated White Sox (69-69), 8-2 | Comiskey Park I (5-6) | 68-70 | Won 2 |
| » Starters: George Uhle vs Larry Duff | Fifth | 16½ out |
| Wednesday, September 13 |
| » Lost to Senators (62-74), 4-1 | League Park II (34-30) | 68-71 | |
| » Starters: George Mogridge vs Dan Boone | Fifth | 17 out |
| Thursday, September 14 |
| » Defeated Senators (62-75), 4-3 | League Park II (35-30) | 69-71 | |
| » Starters: Eric Erickson vs James Edwards | Fifth | 17 out |
| Friday, September 15 |
| » Defeated Senators (62-76), 6-5 | League Park II (36-30) | 70-71 | Won 2 |
| » Starters: Walter Johnson vs Dewey Metivier | Fifth | 16 out |
| Saturday, September 16 |
| » Lost to Athletics (58-82), 6-1 | League Park II (36-31) | 70-72 | |
| » Starters: Eddie Rommel vs George Uhle | Fifth | 17 out |
| Sunday, September 17 |
| » Defeated Athletics (58-83), 4-2 | League Park II (37-31) | 71-72 | |
| » Starters: Bob Hasty vs Dan Boone | Fifth | 16 out |
| Monday, September 18 |
| » Lost to Athletics (59-83), 4-3 | League Park II (37-32) | 71-73 | |
| » Starters: Eddie Rommel vs James Edwards | Fifth | 17 out |
| Tuesday, September 19 |
| » Defeated Red Sox (57-87), 7-4 | League Park II (38-32) | 72-73 | |
| » Starters: Herb Pennock vs Dewey Metivier | Fifth | 16½ out |
| » Defeated Red Sox (57-88), 3-2 | League Park II (39-32) | 73-73 | Won 2 |
| » Starters: Alex Ferguson vs George Winn | Fifth | 16½ out |
| Wednesday, September 20 |
| » Defeated Red Sox (57-89), 5-2 | League Park II (40-32) | 74-73 | Won 3 |
| » Starters: Rip Collins vs George Uhle | Fifth | 16 out |
| » Defeated Red Sox (57-90), 5-4 | League Park II (41-32) | 75-73 | Won 4 |
| » Starters: Bill Piercy vs Phil Bedgood | Fifth | 16 out |
| Thursday, September 21 |
| » Lost to Red Sox (58-90), 15-5 | League Park II (41-33) | 75-74 | |
| » Starters: Jack Quinn vs John Middleton | Fifth | 17 out |
| Friday, September 22 |
| » Lost to Yankees (92-56), 9-3 | League Park II (41-34) | 75-75 | Lost 2 |
| » Starters: Bullet Joe Bush vs James Edwards | Fifth | 18 out |
| Saturday, September 23 |
| » Lost to Yankees (93-56), 7-6 | League Park II (41-35) | 75-76 | Lost 3 |
| » Starters: Sad Sam Jones vs Sherry Smith | Fifth | 19 out |
| Sunday, September 24 |
| » Defeated Yankees (93-57), 3-0 | League Park II (42-35) | 76-76 | |
| » Starters: Bob Shawkey vs George Uhle | Fifth | 18 out |
| Saturday, September 30 |
| » Defeated Tigers (79-74), 4-1 | League Park II (43-35) | 77-76 | Won 2 |
| » Starters: Herman Pillette vs Sherry Smith | Fourth | 17 out |
| Sunday, October 1 |
| » Defeated Tigers (79-75), 6-5 | League Park II (44-35) | 78-76 | Won 3 |
| » Starters: Syl Johnson vs George Uhle | Fourth | 16 out |
| Friday, October 6 |
| Future Indian Joe Frazier is born in Liberty, NC. |
| Friday, October 27 |
| Future Indian Ralph Kiner is born in Santa Rita, NM. |
| Wednesday, November 29 |
| Future Indian Minnie Minos |
