| Friday, January 28 |
| Future Senator Julio Moreno is born in Guines, Cuba. |
| Wednesday, March 2 |
| Future Senator Dick Starr is born in Kittanning, PA. |
| Saturday, March 5 |
| Future Senator Elmer Valo is born in Ribnik, Czechoslovakia. |
| Wednesday, April 13 |
| » Lost to Red Sox (1-0), 6-3 | Griffith Stadium (0-1) | 0-1 | |
| » Starters: Sad Sam Jones vs Walter Johnson | Third | 1 out |
| Thursday, April 14 |
| » Defeated Red Sox (1-1), 8-2 | Griffith Stadium (1-1) | 1-1 | |
| » Starters: Herb Pennock vs Al Schacht | Second | ½ out |
| » Major-league debuts: Curt Fullerton (Red Sox) |
| Friday, April 15 |
| » Defeated Red Sox (1-2), 7-1 | Griffith Stadium (2-1) | 2-1 | Won 2 |
| » Starters: Bullet Joe Bush vs Eric Erickson | First | -- |
| » Major-league debuts: Pinky Pittenger (Red Sox) |
| Saturday, April 16 |
| » Lost to Red Sox (2-2), 8-3 | Griffith Stadium (2-2) | 2-2 | |
| » Starters: Hank Thormahlen vs Tom Zachary | Third | ½ out |
| » Major-league debuts: Bing Miller (Senators) |
| Sunday, April 17 |
| » Defeated Athletics (1-3), 3-1 | Griffith Stadium (3-2) | 3-2 | |
| » Starters: Rollie Naylor vs Walter Johnson | Second | ½ out |
| Tuesday, April 19 |
| » Defeated Athletics (1-4), 14-6 | Griffith Stadium (4-2) | 4-2 | Won 2 |
| » Starters: Eddie Rommel vs Al Schacht | Second | 1 out |
| Wednesday, April 20 |
| » Defeated Athletics (1-5), 6-4 | Griffith Stadium (5-2) | 5-2 | Won 3 |
| » Starters: Bob Hasty vs Eric Erickson | Second | 1 out |
| Thursday, April 21 |
| » Lost to Red Sox (3-4), 1-0 | Fenway Park (0-1) | 5-3 | |
| » Starters: George Mogridge vs Sad Sam Jones | Second | 1 out |
| Sunday, April 24 |
| » Defeated Yankees (5-3), 3-1 | Griffith Stadium (6-2) | 6-3 | |
| » Starters: Bill Piercy vs Tom Zachary | Second | ½ out |
| Monday, April 25 |
| » Defeated Yankees (5-4), 5-3 | Polo Grounds V (1-0) | 7-3 | Won 2 |
| » Starters: Walter Johnson vs Carl Mays | Second | ½ out |
| Tuesday, April 26 |
| » Defeated Yankees (5-5), 5-4 | Polo Grounds V (2-0) | 8-3 | Won 3 |
| » Starters: Al Schacht vs Jack Quinn | Second | ½ out |
| Wednesday, April 27 |
| » Defeated Yankees (5-6), 5-3 | Polo Grounds V (3-0) | 9-3 | Won 4 |
| » Starters: Jim Shaw vs Bob Shawkey | First | -- |
| Thursday, April 28 |
| » Lost to Yankees (6-6), 9-5 | Polo Grounds V (3-1) | 9-4 | |
| » Starters: Tom Zachary vs Bill Piercy | Second | ½ out |
| Friday, April 29 |
| » Tied Athletics, 3-3 | Shibe Park (0-0) | 9-4 | |
| » Starters: Walter Johnson vs Eddie Rommel | First | -- |
| Saturday, April 30 |
| » Defeated Athletics (3-9), 6-5 | Shibe Park (1-0) | 10-4 | |
| » Starters: Jose Acosta vs Roy Moore | First | -- |
| Sunday, May 1 |
| » Lost to Athletics (4-9), 5-1 | Griffith Stadium (6-3) | 10-5 | |
| » Starters: Slim Harriss vs George Mogridge | Second | 1 out |
| Monday, May 2 |
| » Lost to Athletics (5-9), 6-1 | Shibe Park (1-1) | 10-6 | Lost 2 |
| » Starters: Eric Erickson vs Scott Perry | Second | 1½ out |
| Tuesday, May 3 |
| » Defeated Athletics (5-10), 4-2 | Shibe Park (2-1) | 11-6 | |
| » Starters: Tom Zachary vs Roy Moore | Second | 1 out |
| Friday, May 6 |
| » Lost to Yankees (8-7), 9-2 | Griffith Stadium (6-4) | 11-7 | |
| » Starters: Carl Mays vs Eric Erickson | Second | 1½ out |
| Saturday, May 7 |
| » Lost to Yankees (9-7), 6-5 | Griffith Stadium (6-5) | 11-8 | Lost 2 |
| » Starters: Jack Quinn vs Walter Johnson | Second | 2½ out |
| Sunday, May 8 |
| » Lost to Red Sox (8-7), 4-3 | Griffith Stadium (6-6) | 11-9 | Lost 3 |
| » Starters: Sad Sam Jones vs George Mogridge | Second | 3½ out |
| Tuesday, May 10 |
| » Defeated Indians (15-7), 9-7 | League Park II (1-0) | 12-9 | |
| » Starters: Jim Shaw vs Jim Bagby | Second | 2½ out |
| Wednesday, May 11 |
| » Lost to Indians (16-7), 14-1 | League Park II (1-1) | 12-10 | |
| » Starters: Walter Johnson vs Stan Coveleski | Second | 3½ out |
| Thursday, May 12 |
| » Defeated Indians (16-8), 4-1 | League Park II (2-1) | 13-10 | |
| » Starters: Eric Erickson vs Duster Mails | Second | 2½ out |
| Friday, May 13 |
| » Defeated Indians (16-9), 4-2 | League Park II (3-1) | 14-10 | Won 2 |
| » Starters: George Mogridge vs George Uhle | Second | 1½ out |
| Former Senator John Farrell dies in Kansas City, MO at the age of 45. |
| Saturday, May 14 |
| » Lost to Tigers (14-13), 3-2 | Tiger Stadium (0-1) | 14-11 | |
| » Starters: Tom Zachary vs Red Oldham | Third | 1½ out |
| Sunday, May 15 |
| » Lost to Tigers (15-13), 13-10 | Tiger Stadium (0-2) | 14-12 | Lost 2 |
| » Starters: Walter Johnson vs Suds Sutherland | Fourth | 1½ out |
| Monday, May 16 |
| » Lost to Tigers (16-13), 17-11 | Tiger Stadium (0-3) | 14-13 | Lost 3 |
| » Starters: Jim Shaw vs Jim Middleton | Fifth | 2½ out |
| Tuesday, May 17 |
| » Defeated Tigers (16-14), 2-1 | Tiger Stadium (1-3) | 15-13 | |
| » Starters: George Mogridge vs Dutch Leonard | Fourth | 1½ out |
| Wednesday, May 18 |
| » Lost to Browns (13-15), 8-3 | Sportsman's Park III (0-1) | 15-14 | |
| » Starters: Eric Erickson vs Urban Shocker | Fourth | 2½ out |
| Thursday, May 19 |
| » Defeated Browns (13-16), 8-5 | Sportsman's Park III (1-1) | 16-14 | |
| » Starters: Tom Zachary vs Bernie Boland | Fourth | 2½ out |
| Friday, May 20 |
| » Lost to Browns (14-16), 5-4 | Sportsman's Park III (1-2) | 16-15 | |
| » Starters: Walter Johnson vs Dixie Davis | Fifth | 3½ out |
| Saturday, May 21 |
| » Lost to Browns (15-16), 4-2 | Sportsman's Park III (1-3) | 16-16 | Lost 2 |
| » Starters: George Mogridge vs Emilio Palmero | Fifth | 3½ out |
| Sunday, May 22 |
| » Lost to White Sox (13-16), 6-2 | Comiskey Park I (0-1) | 16-17 | Lost 3 |
| » Starters: Harry Courtney vs Red Faber | Fourth | 4½ out |
| Monday, May 23 |
| » Defeated White Sox (13-17), 9-5 | Comiskey Park I (1-1) | 17-17 | |
| » Starters: Tom Zachary vs Lum Davenport | Fourth | 4½ out |
| Tuesday, May 24 |
| » Lost to White Sox (14-17), 6-5 | Comiskey Park I (1-2) | 17-18 | |
| » Starters: Jose Acosta vs Dominic Mulrenan | Fourth | 5 out |
| Wednesday, May 25 |
| » Defeated White Sox (14-18), 10-5 | Comiskey Park I (2-2) | 18-18 | |
| » Starters: George Mogridge vs Roy Wilkinson | Fourth | 5 out |
| Friday, May 27 |
| » Lost to Yankees (20-14), 11-4 | Griffith Stadium (6-7) | 18-19 | |
| » Starters: Waite Hoyt vs Tom Zachary | Fourth | 6½ out |
| Saturday, May 28 |
| » Lost to Red Sox (14-16), 4-3 | Griffith Stadium (6-8) | 18-20 | Lost 2 |
| » Starters: Sad Sam Jones vs Walter Johnson | Fourth | 7½ out |
| Sunday, May 29 |
| » Defeated Red Sox (14-17), 6-0 | Griffith Stadium (7-8) | 19-20 | |
| » Starters: Allen Sothoron vs Eric Erickson | Fourth | 7½ out |
| Monday, May 30 |
| » Lost to Yankees (24-14), 2-1 | Griffith Stadium (7-9) | 19-21 | |
| » Starters: Rip Collins vs Jose Acosta | Fourth | 7½ out |
| » Defeated Yankees (24-15), 1-0 | Griffith Stadium (8-9) | 20-21 | |
| » Starters: Jack Quinn vs George Mogridge | Fourth | 7½ out |
| Tuesday, May 31 |
| » Defeated Yankees (24-16), 12-5 | Griffith Stadium (9-9) | 21-21 | Won 2 |
| » Starters: Waite Hoyt vs Tom Zachary | Fourth | 7½ out |
| Wednesday, June 1 |
| » Defeated Yankees (24-17), 8-7 | Griffith Stadium (10-9) | 22-21 | Won 3 |
| » Starters: Carl Mays vs Walter Johnson | Fourth | 7 out |
| Thursday, June 2 |
| » Defeated White Sox (17-24), 7-2 | Griffith Stadium (11-9) | 23-21 | Won 4 |
| » Starters: Dickie Kerr vs Harry Courtney | Fourth | 7 out |
| Friday, June 3 |
| » Lost to White Sox (18-24), 8-3 | Griffith Stadium (11-10) | 23-22 | |
| » Starters: Red Faber vs George Mogridge | Fourth | 7 out |
| Saturday, June 4 |
| » Defeated White Sox (18-25), 9-4 | Griffith Stadium (12-10) | 24-22 | |
| » Starters: Roy Wilkinson vs Jose Acosta | Fourth | 6 out |
| Sunday, June 5 |
| » Defeated White Sox (18-26), 9-2 | Griffith Stadium (13-10) | 25-22 | Won 2 |
| » Starters: Shovel Hodge vs Walter Johnson | Third | 5½ out |
| Monday, June 6 |
| » Defeated White Sox (18-27), 10-7 | Griffith Stadium (14-10) | 26-22 | Won 3 |
| » Starters: Dickie Kerr vs Harry Courtney | Third | 4½ out |
| Tuesday, June 7 |
| » Defeated Tigers (27-24), 3-2 | Griffith Stadium (15-10) | 27-22 | Won 4 |
| » Starters: Dutch Leonard vs Tom Zachary | Third | 3½ out |
| Wednesday, June 8 |
| » Defeated Tigers (27-25), 6-2 | Griffith Stadium (16-10) | 28-22 | Won 5 |
| » Starters: Red Oldham vs George Mogridge | Third | 2½ out |
| Thursday, June 9 |
| » Lost to Tigers (28-25), 10-6 | Griffith Stadium (16-11) | 28-23 | |
| » Starters: Howard Ehmke vs Walter Johnson | Third | 3½ out |
| Friday, June 10 |
| » Lost to Tigers (29-25), 6-3 | Griffith Stadium (16-12) | 28-24 | Lost 2 |
| » Starters: Hooks Dauss vs Harry Courtney | Third | 4½ out |
| Saturday, June 11 |
| » Lost to Indians (33-19), 7-3 | Griffith Stadium (16-13) | 28-25 | Lost 3 |
| » Starters: Stan Coveleski vs Tom Zachary | Third | 5½ out |
| Sunday, June 12 |
| » Defeated Indians (33-20), 10-3 | Griffith Stadium (17-13) | 29-25 | |
| » Starters: George Uhle vs George Mogridge | Third | 4½ out |
| Monday, June 13 |
| » Lost to Indians (34-20), 10-6 | Griffith Stadium (17-14) | 29-26 | |
| » Starters: Ray Caldwell vs Eric Erickson | Third | 5½ out |
| Tuesday, June 14 |
| » Defeated Indians (34-21), 8-7 | Griffith Stadium (18-14) | 30-26 | |
| » Starters: Jim Bagby vs Jim Shaw | Third | 4½ out |
| Wednesday, June 15 |
| » Defeated Browns (25-30), 7-5 | Griffith Stadium (19-14) | 31-26 | Won 2 |
| » Starters: Urban Shocker vs Harry Courtney | Third | 4½ out |
| Thursday, June 16 |
| » Defeated Browns (25-31), 6-3 | Griffith Stadium (20-14) | 32-26 | Won 3 |
| » Starters: Emilio Palmero vs Jose Acosta | Third | 4½ out |
| Friday, June 17 |
| » Defeated Browns (25-32), 5-4 | Griffith Stadium (21-14) | 33-26 | Won 4 |
| » Starters: Bernie Boland vs George Mogridge | Third | 4 out |
| Saturday, June 18 |
| » Defeated Browns (25-33), 5-3 | Griffith Stadium (22-14) | 34-26 | Won 5 |
| » Starters: Bill Bayne vs Tom Zachary | Third | 3 out |
| Sunday, June 19 |
| » Lost to Browns (26-33), 2-1 | Griffith Stadium (22-15) | 34-27 | |
| » Starters: Dixie Davis vs Walter Johnson | Third | 4 out |
| Monday, June 20 |
| » Lost to Athletics (20-36), 7-2 | Shibe Park (2-2) | 34-28 | Lost 2 |
| » Starters: Jose Acosta vs Roy Moore | Third | 4 out |
| » Defeated Athletics (20-37), 4-2 | Shibe Park (3-2) | 35-28 | |
| » Starters: Harry Courtney vs Bob Hasty | Third | 4 out |
| Tuesday, June 21 |
| » Lost to Athletics (21-37), 7-6 | Shibe Park (3-3) | 35-29 | |
| » Starters: George Mogridge vs Rollie Naylor | Third | 5 out |
| Wednesday, June 22 |
| » Defeated Athletics (21-38), 5-4 | Shibe Park (4-3) | 36-29 | |
| » Starters: Tom Zachary vs Dave Keefe | Third | 5 out |
| Thursday, June 23 |
| » Lost to Athletics (22-38), 5-3 | Shibe Park (4-4) | 36-30 | |
| » Starters: Al Schacht vs Slim Harriss | Third | 5 out |
| Friday, June 24 |
| » Lost to Yankees (38-27), 9-3 | Polo Grounds V (3-2) | 36-31 | Lost 2 |
| » Starters: Harry Courtney vs Carl Mays | Third | 6 out |
| Saturday, June 25 |
| » Defeated Yankees (38-28), 6-4 | Polo Grounds V (4-2) | 37-31 | |
| » Starters: Walter Johnson vs Bob Shawkey | Third | 5 out |
| Sunday, June 26 |
| » Lost to Yankees (39-28), 9-1 | Polo Grounds V (4-3) | 37-32 | |
| » Starters: George Mogridge vs Waite Hoyt | Third | 6 out |
| Wednesday, June 29 |
| » Lost to Athletics (26-40), 5-1 | Griffith Stadium (22-16) | 37-33 | Lost 2 |
| » Starters: Slim Harriss vs Tom Zachary | Third | 8 out |
| Thursday, June 30 |
| » Major-league debuts: Luke Sewell (Indians) |
| Friday, July 1 |
| » Lost to Athletics (27-40), 2-1 | Griffith Stadium (22-17) | 37-34 | Lost 3 |
| » Starters: Roy Moore vs Walter Johnson | Third | 7½ out |
| » Defeated Athletics (27-41), 1-0 | Griffith Stadium (23-17) | 38-34 | |
| » Starters: Bob Hasty vs George Mogridge | Third | 7½ out |
| Saturday, July 2 |
| » Lost to Athletics (28-41), 6-1 | Griffith Stadium (23-18) | 38-35 | |
| » Starters: Rollie Naylor vs Harry Courtney | Third | 7½ out |
| Sunday, July 3 |
| » Lost to Athletics (29-41), 12-4 | Griffith Stadium (23-19) | 38-36 | Lost 2 |
| » Starters: Slim Harriss vs Al Schacht | Third | 8½ out |
| Monday, July 4 |
| » Defeated Red Sox (32-36), 4-1 | Fenway Park (1-1) | 39-36 | |
| » Starters: Tom Zachary vs Sad Sam Jones | Third | 8½ out |
| » Defeated Red Sox (32-37), 7-3 | Fenway Park (2-1) | 40-36 | Won 2 |
| » Starters: Harry Courtney vs Bullet Joe Bush | Third | 8½ out |
| Tuesday, July 5 |
| » Defeated Red Sox (32-38), 7-5 | Fenway Park (3-1) | 41-36 | Won 3 |
| » Starters: George Mogridge vs Herb Pennock | Third | 8 out |
| » Defeated Red Sox (32-39), 4-1 | Fenway Park (4-1) | 42-36 | Won 4 |
| » Starters: Walter Johnson vs Elmer Myers | Third | 8 out |
| Future Senator Al Kozar is born in McKees Rocks, PA. |
| Wednesday, July 6 |
| » Lost to Red Sox (33-39), 2-1 | Fenway Park (4-2) | 42-37 | |
| » Starters: George Mogridge vs Allen Russell | Third | 8 out |
| » Defeated Red Sox (33-40), 1-0 | Fenway Park (5-2) | 43-37 | |
| » Starters: Eric Erickson vs Sad Sam Jones | Third | 8 out |
| Friday, July 8 |
| » Lost to Browns (33-44), 12-2 | Sportsman's Park III (1-4) | 43-38 | |
| » Starters: Tom Zachary vs Dixie Davis | Third | 8 out |
| Saturday, July 9 |
| » Lost to Browns (34-44), 12-3 | Sportsman's Park III (1-5) | 43-39 | Lost 2 |
| » Starters: Harry Courtney vs Urban Shocker | Third | 8 out |
| Sunday, July 10 |
| » Defeated Browns (34-45), 9-4 | Sportsman's Park III (2-5) | 44-39 | |
| » Starters: George Mogridge vs Elam Vangilder | Third | 8½ out |
| Monday, July 11 |
| » Lost to Browns (35-45), 5-4 | Sportsman's Park III (2-6) | 44-40 | |
| » Starters: Eric Erickson vs Ray Kolp | Third | 9 out |
| Tuesday, July 12 |
| » Defeated White Sox (33-46), 8-7 | Comiskey Park I (3-2) | 45-40 | |
| » Starters: Harry Courtney vs Roy Wilkinson | Third | 9½ out |
| Wednesday, July 13 |
| » Defeated White Sox (33-47), 10-9 | Comiskey Park I (4-2) | 46-40 | Won 2 |
| » Starters: Jim Shaw vs Shovel Hodge | Third | 9½ out |
| Thursday, July 14 |
| » Lost to White Sox (34-47), 3-1 | Comiskey Park I (4-3) | 46-41 | |
| » Starters: George Mogridge vs Red Faber | Third | 9½ out |
| Friday, July 15 |
| » Lost to White Sox (35-47), 3-2 | Comiskey Park I (4-4) | 46-42 | Lost 2 |
| » Starters: Eric Erickson vs Dickie Kerr | Third | 9½ out |
| Saturday, July 16 |
| » Lost to Indians (54-30), 8-4 | League Park II (3-2) | 46-43 | Lost 3 |
| » Starters: Harry Courtney vs Stan Coveleski | Third | 10½ out |
| Sunday, July 17 |
| » Defeated Indians (54-31), 13-2 | League Park II (4-2) | 47-43 | |
| » Starters: Tom Zachary vs Ray Caldwell | Third | 9½ out |
| Monday, July 18 |
| » Lost to Indians (55-31), 3-2 | League Park II (4-3) | 47-44 | |
| » Starters: George Mogridge vs Allen Sothoron | Third | 10½ out |
| Tuesday, July 19 |
| » Lost to Indians (56-31), 6-4 | League Park II (4-4) | 47-45 | Lost 2 |
| » Starters: Eric Erickson vs Duster Mails | Third | 11½ out |
| Wednesday, July 20 |
| » Lost to Tigers (43-47), 2-1 | Tiger Stadium (1-4) | 47-46 | Lost 3 |
| » Starters: Walter Johnson vs Dutch Leonard | Third | 11½ out |
| Thursday, July 21 |
| » Lost to Tigers (44-47), 7-2 | Tiger Stadium (1-5) | 47-47 | Lost 4 |
| » Starters: Tom Zachary vs Red Oldham | Third | 12½ out |
| Friday, July 22 |
| Future Senator Al LaMacchia is born in St. Louis, MO. |
| Saturday, July 23 |
| » Lost to Tigers (45-47), 6-2 | Tiger Stadium (1-6) | 47-48 | Lost 5 |
| » Starters: George Mogridge vs Howard Ehmke | Third | 13½ out |
| Sunday, July 24 |
| » Defeated Tigers (45-48), 14-6 | Tiger Stadium (2-6) | 48-48 | |
| » Starters: Walter Johnson vs Hooks Dauss | Third | 12½ out |
| Monday, July 25 |
| Future Senator Sandy Ullrich is born in Havana, Cuba. |
| Tuesday, July 26 |
| » Defeated White Sox (40-52), 2-0 | Griffith Stadium (24-19) | 49-48 | Won 2 |
| » Starters: Red Faber vs Tom Zachary | Third | 12½ out |
| Wednesday, July 27 |
| » Defeated White Sox (40-53), 5-4 | Griffith Stadium (25-19) | 50-48 | Won 3 |
| » Starters: Dickie Kerr vs George Mogridge | Third | 11½ out |
| Thursday, July 28 |
| » Defeated White Sox (40-54), 8-5 | Griffith Stadium (26-19) | 51-48 | Won 4 |
| » Starters: Shovel Hodge vs Eric Erickson | Third | 11½ out |
| Saturday, July 30 |
| » Defeated Tigers (48-50), 4-3 | Griffith Stadium (27-19) | 52-48 | Won 5 |
| » Starters: Dutch Leonard vs Walter Johnson | Third | 12 out |
| Sunday, July 31 |
| » Defeated Tigers (48-51), 9-5 | Griffith Stadium (28-19) | 53-48 | Won 6 |
| » Starters: Hooks Dauss vs Tom Zachary | Third | 11 out |
| Monday, August 1 |
| » Defeated Tigers (48-52), 1-0 | Griffith Stadium (29-19) | 54-48 | Won 7 |
| » Starters: Red Oldham vs George Mogridge | Third | 10 out |
| Tuesday, August 2 |
| » Defeated Tigers (48-53), 5-4 | Griffith Stadium (30-19) | 55-48 | Won 8 |
| » Starters: Howard Ehmke vs Harry Courtney | Third | 9½ out |
| Thursday, August 4 |
| » Defeated Indians (62-37), 3-1 | Griffith Stadium (31-19) | 56-48 | Won 9 |
| » Starters: Stan Coveleski vs Walter Johnson | Third | 7 out |
| » Defeated Indians (62-38), 3-1 | Griffith Stadium (32-19) | 57-48 | Won 10 |
| » Starters: Guy Morton vs Eric Erickson | Third | 7 out |
| Friday, August 5 |
| » Defeated Indians (62-39), 4-1 | Griffith Stadium (33-19) | 58-48 | Won 11 |
| » Starters: Jim Bagby vs George Mogridge | Third | 7 out |
| Saturday, August 6 |
| » Lost to Indians (63-39), 3-1 | Griffith Stadium (33-20) | 58-49 | |
| » Starters: George Uhle vs Tom Zachary | Third | 7 out |
| Sunday, August 7 |
| » Lost to Browns (49-53), 8-3 | Griffith Stadium (33-21) | 58-50 | Lost 2 |
| » Starters: Urban Shocker vs Harry Courtney | Third | 8 out |
| Monday, August 8 |
| » Defeated Browns (49-54), 16-5 | Griffith Stadium (34-21) | 59-50 | |
| » Starters: Bill Bayne vs Walter Johnson | Third | 9 out |
| Tuesday, August 9 |
| » Lost to Browns (50-54), 8-6 | Griffith Stadium (34-22) | 59-51 | |
| » Starters: Dixie Davis vs George Mogridge | Third | 9 out |
| Wednesday, August 10 |
| » Lost to Browns (51-54), 5-2 | Griffith Stadium (34-23) | 59-52 | Lost 2 |
| » Starters: Urban Shocker vs Tom Zachary | Third | 8½ out |
| Saturday, August 13 |
| » Defeated Red Sox (49-57), 6-1 | Griffith Stadium (35-23) | 60-52 | |
| » Starters: Elmer Myers vs Walter Johnson | Third | 9½ out |
| Sunday, August 14 |
| » Lost to Red Sox (50-57), 2-0 | Griffith Stadium (35-24) | 60-53 | |
| » Starters: Sad Sam Jones vs Eric Erickson | Third | 9½ out |
| Wednesday, August 17 |
| » Lost to Browns (56-55), 7-2 | Sportsman's Park III (2-7) | 60-54 | Lost 2 |
| » Starters: George Mogridge vs Urban Shocker | Third | 10½ out |
| Thursday, August 18 |
| » Defeated Browns (56-56), 13-1 | Sportsman's Park III (3-7) | 61-54 | |
| » Starters: Walter Johnson vs Dixie Davis | Third | 9½ out |
| Friday, August 19 |
| » Defeated Browns (56-57), 6-2 | Sportsman's Park III (4-7) | 62-54 | Won 2 |
| » Starters: Tom Zachary vs Elam Vangilder | Third | 9½ out |
| Saturday, August 20 |
| » Defeated White Sox (49-65), 1-0 | Comiskey Park I (5-4) | 63-54 | Won 3 |
| » Starters: Eric Erickson vs John Russell | Third | 9½ out |
| Sunday, August 21 |
| » Defeated White Sox (49-66), 3-0 | Comiskey Park I (6-4) | 64-54 | Won 4 |
| » Starters: George Mogridge vs Roy Wilkinson | Third | 9½ out |
| Future Senator Lou Knerr is born in Strasburg, PA. |
| Monday, August 22 |
| » Lost to White Sox (50-66), 5-4 | Comiskey Park I (6-5) | 64-55 | |
| » Starters: Jose Acosta vs Jack Wieneke | Third | 9½ out |
| Tuesday, August 23 |
| » Lost to Tigers (57-64), 12-3 | Tiger Stadium (2-7) | 64-56 | Lost 2 |
| » Starters: Tom Zachary vs Red Oldham | Third | 9½ out |
| Wednesday, August 24 |
| » Lost to Tigers (58-64), 15-1 | Tiger Stadium (2-8) | 64-57 | Lost 3 |
| » Starters: Walter Johnson vs Bert Cole | Third | 10 out |
| Thursday, August 25 |
| » Defeated Tigers (58-65), 9-1 | Tiger Stadium (3-8) | 65-57 | |
| » Starters: George Mogridge vs Dutch Leonard | Third | 9½ out |
| Friday, August 26 |
| » Lost to Indians (74-46), 6-3 | League Park II (4-5) | 65-58 | |
| » Starters: Eric Erickson vs Duster Mails | Third | 10½ out |
| Saturday, August 27 |
| » Lost to Indians (75-46), 6-2 | League Park II (4-6) | 65-59 | Lost 2 |
| » Starters: Tom Zachary vs George Uhle | Third | 11½ out |
| Sunday, August 28 |
| » Lost to Indians (76-46), 3-2 | League Park II (4-7) | 65-60 | Lost 3 |
| » Starters: George Mogridge vs Stan Coveleski | Third | 12½ out |
| Tuesday, August 30 |
| » Lost to Yankees (74-46), 10-3 | Griffith Stadium (35-25) | 65-61 | Lost 4 |
| » Starters: Carl Mays vs Eric Erickson | Third | 13 out |
| Wednesday, August 31 |
| » Lost to Yankees (75-46), 17-9 | Griffith Stadium (35-26) | 65-62 | Lost 5 |
| » Starters: Rip Collins vs Tom Zachary | Fourth | 13½ out |
| Thursday, September 1 |
| » Lost to Yankees (76-46), 6-3 | Polo Grounds V (4-4) | 65-63 | Lost 6 |
| » Starters: George Mogridge vs Bob Shawkey | Fourth | 15 out |
| » Lost to Yankees (77-46), 8-1 | Polo Grounds V (4-5) | 65-64 | Lost 7 |
| » Starters: Walter Johnson vs Harry Harper | Fourth | 15 out |
| Friday, September 2 |
| » Lost to Yankees (78-46), 9-3 | Polo Grounds V (4-6) | 65-65 | Lost 8 |
| » Starters: Eric Erickson vs Waite Hoyt | Fourth | 16 out |
| Saturday, September 3 |
| » Lost to Yankees (79-46), 9-3 | Polo Grounds V (4-7) | 65-66 | Lost 9 |
| » Starters: Harry Courtney vs Carl Mays | Fourth | 17 out |
| Monday, September 5 |
| » Lost to Athletics (45-80), 4-3 | Shibe Park (4-5) | 65-67 | Lost 10 |
| » Starters: Walter Johnson vs Bob Hasty | Fourth | 17 out |
| » Defeated Athletics (45-81), 7-1 | Shibe Park (5-5) | 66-67 | |
| » Starters: George Mogridge vs Eddie Rommel | Fourth | 17 out |
| Tuesday, September 6 |
| » Lost to Athletics (46-81), 7-1 | Shibe Park (5-6) | 66-68 | |
| » Starters: Tom Zachary vs Roy Moore | Fourth | 17 out |
| Friday, September 9 |
| » Lost to Red Sox (63-66), 5-1 | Griffith Stadium (35-27) | 66-69 | Lost 2 |
| » Starters: Sad Sam Jones vs George Mogridge | Fourth | 18½ out |
| Saturday, September 10 |
| » Defeated Red Sox (63-67), 5-3 | Griffith Stadium (36-27) | 67-69 | |
| » Starters: Allen Russell vs Walter Johnson | Fourth | 18½ out |
| Sunday, September 11 |
| » Defeated Athletics (47-84), 7-6 | Griffith Stadium (37-27) | 68-69 | Won 2 |
| » Starters: Slim Harriss vs Frank Woodward | Fourth | 18 out |
| Tuesday, September 13 |
| » Lost to Browns (72-67), 15-1 | Griffith Stadium (37-28) | 68-70 | |
| » Starters: Urban Shocker vs George Mogridge | Fourth | 18 out |
| Wednesday, September 14 |
| » Defeated Browns (72-68), 1-0 | Griffith Stadium (38-28) | 69-70 | |
| » Starters: Dixie Davis vs Walter Johnson | Fourth | 18 out |
| Friday, September 16 |
| » Lost to Indians (89-52), 2-0 | Griffith Stadium (38-29) | 69-71 | |
| » Starters: George Uhle vs Eric Erickson | Fourth | 19½ out |
| » Major-league debuts: Goose Goslin (Senators) |
| Saturday, September 17 |
| » Lost to Indians (90-52), 8-4 | Griffith Stadium (38-30) | 69-72 | Lost 2 |
| » Starters: Allen Sothoron vs George Mogridge | Fifth | 20½ out |
| Sunday, September 18 |
| » Defeated Indians (90-53), 4-1 | Griffith Stadium (39-30) | 70-72 | |
| » Starters: Stan Coveleski vs Walter Johnson | Fourth | 19½ out |
| Tuesday, September 20 |
| » Defeated White Sox (58-85), 9-0 | Griffith Stadium (40-30) | 71-72 | Won 2 |
| » Starters: Dickie Kerr vs Tom Zachary | Fifth | 19 out |
| Wednesday, September 21 |
| » Defeated White Sox (58-86), 3-2 | Griffith Stadium (41-30) | 72-72 | Won 3 |
| » Starters: Red Faber vs Tom Phillips | Fourth | 18 out |
| » Defeated White Sox (58-87), 4-3 | Griffith Stadium (42-30) | 73-72 | Won 4 |
| » Starters: John Russell vs Eric Erickson | Fourth | 18 out |
| Friday, September 23 |
| » Defeated Tigers (71-78), 2-1 | Griffith Stadium (43-30) | 74-72 | Won 5 |
| » Starters: Dutch Leonard vs George Mogridge | Fourth | 18½ out |
| Saturday, September 24 |
| » Defeated Tigers (71-79), 5-1 | Griffith Stadium (44-30) | 75-72 | Won 6 |
| » Starters: Red Oldham vs Walter Johnson | Fourth | 17½ out |
| » Major-league debuts: Jackie Tavener (Tigers) |
| Future Senator Clyde Vollmer is born in Cincinnati, OH. |
| Sunday, September 25 |
| » Defeated Tigers (71-80), 3-2 | Griffith Stadium (45-30) | 76-72 | Won 7 |
| » Starters: Bert Cole vs Tom Zachary | Fourth | 17½ out |
| Thursday, September 29 |
| » Lost to Red Sox (75-75), 5-2 | Fenway Park (5-3) | 76-73 | |
| » Starters: Walter Johnson vs Sad Sam Jones | Fourth | 18½ out |
| Friday, September 30 |
| » Defeated Red Sox (75-76), 6-4 | Fenway Park (6-3) | 77-73 | |
| » Starters: George Mogridge vs Bullet Joe Bush | Fourth | 18 out |
| Saturday, October 1 |
| » Defeated Red Sox (75-77), 7-2 | Fenway Park (7-3) | 78-73 | Won 2 |
| » Starters: Tom Zachary vs Herb Pennock | Fourth | 18 out |
| » Defeated Red Sox (75-78), 6-1 | Fenway Park (8-3) | 79-73 | Won 3 |
| » Starters: Eric Erickson vs Benn Karr | Fourth | 18 out |
| Sunday, October 2 |
| » Defeated Athletics (53-100), 11-6 | Griffith Stadium (46-30) | 80-73 | Won 4 |
| » Starters: Roy Moore vs Walter Johnson | Fourth | 18 out |
| Friday, October 7 |
| Future Senator Al Sima is born in Mahwah, NJ. |
Game information provided by Retrosheet (www.retrosheet.org) |