| Tuesday, February 8 |
| Future Red Sox Hoot Evers is born in St. Louis, MO. |
| Sunday, February 20 |
| Future Red Sox Jack Robinson is born in Orange, NJ. |
| Monday, March 14 |
| Future Red Sox Bill Kennedy is born in Carnesville, GA. |
| Thursday, March 24 |
| Former Red Sox Larry McLean dies in Boston, MA at the age of 40. |
| Wednesday, April 13 |
| » Defeated Senators (0-1), 6-3 | Griffith Stadium (1-0) | 1-0 | |
| » Starters: Sad Sam Jones vs Walter Johnson | First | -- |
| Thursday, April 14 |
| » Lost to Senators (1-1), 8-2 | Griffith Stadium (1-1) | 1-1 | |
| » Starters: Herb Pennock vs Al Schacht | Second | ½ out |
| » Major-league debuts: Curt Fullerton (Red Sox) |
| Friday, April 15 |
| » Lost to Senators (2-1), 7-1 | Griffith Stadium (1-2) | 1-2 | Lost 2 |
| » Starters: Bullet Joe Bush vs Eric Erickson | Third | 1 out |
| » Major-league debuts: Pinky Pittenger (Red Sox) |
| Saturday, April 16 |
| » Defeated Senators (2-2), 8-3 | Griffith Stadium (2-2) | 2-2 | |
| » Starters: Hank Thormahlen vs Tom Zachary | Third | ½ out |
| » Major-league debuts: Bing Miller (Senators) |
| Sunday, April 17 |
| » Lost to Yankees (3-1), 4-0 | Polo Grounds V (0-1) | 2-3 | |
| » Starters: Sad Sam Jones vs Carl Mays | Fifth | 1½ out |
| Wednesday, April 20 |
| » Lost to Yankees (4-1), 8-4 | Polo Grounds V (0-2) | 2-4 | Lost 2 |
| » Starters: Allen Russell vs Jack Quinn | Sixth | 2½ out |
| Thursday, April 21 |
| » Defeated Senators (5-3), 1-0 | Fenway Park (1-0) | 3-4 | |
| » Starters: George Mogridge vs Sad Sam Jones | Fourth | 2½ out |
| Monday, April 25 |
| » Defeated Athletics (2-7), 3-2 | Fenway Park (2-0) | 4-4 | Won 2 |
| » Starters: Slim Harriss vs Sad Sam Jones | Fourth | 2½ out |
| Tuesday, April 26 |
| » Lost to Athletics (3-7), 2-1 | Fenway Park (2-1) | 4-5 | |
| » Starters: Roy Moore vs Herb Pennock | Fifth | 3½ out |
| Thursday, April 28 |
| » Defeated Athletics (3-8), 6-2 | Fenway Park (3-1) | 5-5 | |
| » Starters: Scott Perry vs Bullet Joe Bush | Third | 3 out |
| Monday, May 2 |
| » Defeated Yankees (6-7), 2-1 | Fenway Park (4-1) | 6-5 | Won 2 |
| » Starters: Carl Mays vs Sad Sam Jones | Third | 3 out |
| Tuesday, May 3 |
| » Lost to Yankees (7-7), 2-0 | Fenway Park (4-2) | 6-6 | |
| » Starters: Bill Piercy vs Herb Pennock | Third | 3½ out |
| Friday, May 6 |
| » Lost to Athletics (6-10), 10-6 | Shibe Park (0-1) | 6-7 | Lost 2 |
| » Starters: Elmer Myers vs Eddie Rommel | Fifth | 4 out |
| Saturday, May 7 |
| » Defeated Athletics (6-11), 6-2 | Shibe Park (1-1) | 7-7 | |
| » Starters: Herb Pennock vs Slim Harriss | Fifth | 4 out |
| Sunday, May 8 |
| » Defeated Senators (11-9), 4-3 | Griffith Stadium (3-2) | 8-7 | Won 2 |
| » Starters: Sad Sam Jones vs George Mogridge | Third | 4 out |
| Tuesday, May 10 |
| » Lost to White Sox (6-12), 4-1 | Comiskey Park I (0-1) | 8-8 | |
| » Starters: Bullet Joe Bush vs Red Faber | Fifth | 4 out |
| Wednesday, May 11 |
| » Defeated White Sox (6-13), 3-2 | Comiskey Park I (1-1) | 9-8 | |
| » Starters: Herb Pennock vs Dominic Mulrenan | Fourth | 4 out |
| Friday, May 13 |
| » Defeated White Sox (6-14), 16-8 | Comiskey Park I (2-1) | 10-8 | Won 2 |
| » Starters: Sad Sam Jones vs Dickie Kerr | Fourth | 3½ out |
| Saturday, May 14 |
| » Lost to Browns (11-13), 8-6 | Sportsman's Park III (0-1) | 10-9 | |
| » Starters: Hank Thormahlen vs Bernie Boland | Fourth | 3½ out |
| Sunday, May 15 |
| » Defeated Browns (11-14), 11-7 | Sportsman's Park III (1-1) | 11-9 | |
| » Starters: Elmer Myers vs Bill Burwell | Third | 1½ out |
| Monday, May 16 |
| » Defeated Browns (11-15), 10-5 | Sportsman's Park III (2-1) | 12-9 | Won 2 |
| » Starters: Bullet Joe Bush vs Allen Sothoron | Third | 1½ out |
| Tuesday, May 17 |
| » Lost to Browns (12-15), 4-2 | Sportsman's Park III (2-2) | 12-10 | |
| » Starters: Herb Pennock vs Dixie Davis | Third | 1½ out |
| Wednesday, May 18 |
| » Defeated Tigers (16-15), 2-0 | Tiger Stadium (1-0) | 13-10 | |
| » Starters: Sad Sam Jones vs Hooks Dauss | Third | 3½ out |
| Thursday, May 19 |
| » Lost to Tigers (17-15), 3-2 | Tiger Stadium (1-1) | 13-11 | |
| » Starters: Hank Thormahlen vs Carl Holling | Third | 3½ out |
| Friday, May 20 |
| » Lost to Tigers (18-15), 12-2 | Tiger Stadium (1-2) | 13-12 | Lost 2 |
| » Starters: Elmer Myers vs Howard Ehmke | Fourth | 3½ out |
| Saturday, May 21 |
| » Lost to Tigers (19-15), 6-5 | Tiger Stadium (1-3) | 13-13 | Lost 3 |
| » Starters: Herb Pennock vs Doc Ayers | Fourth | 3½ out |
| Sunday, May 22 |
| » Lost to Indians (21-13), 5-0 | League Park II (0-1) | 13-14 | Lost 4 |
| » Starters: Sad Sam Jones vs Stan Coveleski | Fifth | 4½ out |
| Monday, May 23 |
| » Lost to Indians (22-13), 4-1 | League Park II (0-2) | 13-15 | Lost 5 |
| » Starters: Hank Thormahlen vs Jim Bagby | Fifth | 5½ out |
| Wednesday, May 25 |
| » Lost to Indians (23-13), 3-2 | League Park II (0-3) | 13-16 | Lost 6 |
| » Starters: Herb Pennock vs George Uhle | Sixth | 6½ out |
| Saturday, May 28 |
| » Defeated Senators (18-20), 4-3 | Griffith Stadium (4-2) | 14-16 | |
| » Starters: Sad Sam Jones vs Walter Johnson | Fifth | 7½ out |
| Sunday, May 29 |
| » Lost to Senators (19-20), 6-0 | Griffith Stadium (4-3) | 14-17 | |
| » Starters: Allen Sothoron vs Eric Erickson | Fifth | 8½ out |
| Monday, May 30 |
| » Lost to Athletics (13-24), 8-1 | Shibe Park (1-2) | 14-18 | Lost 2 |
| » Starters: Hank Thormahlen vs Scott Perry | Seventh | 9½ out |
| » Lost to Athletics (14-24), 2-1 | Shibe Park (1-3) | 14-19 | Lost 3 |
| » Starters: Allen Russell vs Eddie Rommel | Seventh | 9½ out |
| Tuesday, May 31 |
| » Defeated Athletics (14-25), 5-3 | Shibe Park (2-3) | 15-19 | |
| » Starters: Elmer Myers vs Slim Harriss | Fifth | 9 out |
| » Defeated Athletics (14-26), 8-4 | Shibe Park (3-3) | 16-19 | Won 2 |
| » Starters: Herb Pennock vs Bob Hasty | Fifth | 9 out |
| Wednesday, June 1 |
| » Defeated Athletics (14-27), 6-3 | Shibe Park (4-3) | 17-19 | Won 3 |
| » Starters: Sad Sam Jones vs Scott Perry | Fifth | 9 out |
| » Lost to Athletics (15-27), 3-2 | Shibe Park (4-4) | 17-20 | |
| » Starters: Bullet Joe Bush vs Eddie Rommel | Fifth | 9 out |
| Thursday, June 2 |
| » Lost to Indians (30-14), 8-4 | Fenway Park (4-3) | 17-21 | Lost 2 |
| » Starters: George Uhle vs Allen Sothoron | Fifth | 10 out |
| Friday, June 3 |
| » Defeated Indians (30-15), 7-6 | Fenway Park (5-3) | 18-21 | |
| » Starters: Stan Coveleski vs Allen Russell | Fifth | 9 out |
| Saturday, June 4 |
| » Defeated Indians (30-16), 6-0 | Fenway Park (6-3) | 19-21 | Won 2 |
| » Starters: Jim Bagby vs Sad Sam Jones | Fifth | 8 out |
| Monday, June 6 |
| » Defeated Indians (30-17), 7-6 | Fenway Park (7-3) | 20-21 | Won 3 |
| » Starters: Duster Mails vs Herb Pennock | Fifth | 7 out |
| Tuesday, June 7 |
| » Defeated Browns (21-27), 7-6 | Fenway Park (8-3) | 21-21 | Won 4 |
| » Starters: Ray Richmond vs Bullet Joe Bush | Fifth | 6 out |
| Wednesday, June 8 |
| » Lost to Browns (22-27), 2-1 | Fenway Park (8-4) | 21-22 | |
| » Starters: Ray Kolp vs Sad Sam Jones | Fifth | 6 out |
| Thursday, June 9 |
| » Lost to Browns (23-27), 9-3 | Fenway Park (8-5) | 21-23 | Lost 2 |
| » Starters: Elam Vangilder vs Hank Thormahlen | Fifth | 7 out |
| Friday, June 10 |
| » Defeated Browns (23-28), 7-3 | Fenway Park (9-5) | 22-23 | |
| » Starters: Dixie Davis vs Elmer Myers | Fifth | 7 out |
| Saturday, June 11 |
| » Defeated White Sox (20-29), 4-2 | Fenway Park (10-5) | 23-23 | Won 2 |
| » Starters: Dominic Mulrenan vs Herb Pennock | Fifth | 7 out |
| Monday, June 13 |
| » Lost to White Sox (21-29), 6-4 | Fenway Park (10-6) | 23-24 | |
| » Starters: Red Faber vs Sad Sam Jones | Fifth | 7½ out |
| Tuesday, June 14 |
| » Lost to White Sox (22-29), 8-6 | Fenway Park (10-7) | 23-25 | Lost 2 |
| » Starters: Doug McWeeny vs Sad Sam Jones | Fifth | 7½ out |
| Thursday, June 16 |
| » Defeated Tigers (29-30), 8-3 | Fenway Park (11-7) | 24-25 | |
| » Starters: Jim Middleton vs Elmer Myers | Fifth | 8 out |
| Friday, June 17 |
| » Defeated Tigers (29-31), 5-4 | Fenway Park (12-7) | 25-25 | Won 2 |
| » Starters: Pol Perritt vs Herb Pennock | Fourth | 7 out |
| » Defeated Tigers (29-32), 6-4 | Fenway Park (13-7) | 26-25 | Won 3 |
| » Starters: Howard Ehmke vs Bullet Joe Bush | Fourth | 7 out |
| Saturday, June 18 |
| » Defeated Tigers (29-33), 11-7 | Fenway Park (14-7) | 27-25 | Won 4 |
| » Starters: Hooks Dauss vs Sad Sam Jones | Fourth | 6 out |
| Monday, June 20 |
| » Lost to Yankees (35-24), 7-6 | Fenway Park (14-8) | 27-26 | |
| » Starters: Carl Mays vs Elmer Myers | Fourth | 7 out |
| Tuesday, June 21 |
| » Defeated Yankees (35-25), 8-3 | Fenway Park (15-8) | 28-26 | |
| » Starters: Bob Shawkey vs Herb Pennock | Fourth | 6½ out |
| » Defeated Yankees (35-26), 6-1 | Fenway Park (16-8) | 29-26 | Won 2 |
| » Starters: Waite Hoyt vs Bullet Joe Bush | Fourth | 6½ out |
| Wednesday, June 22 |
| » Lost to Yankees (36-26), 8-2 | Fenway Park (16-9) | 29-27 | |
| » Starters: Jack Quinn vs Sad Sam Jones | Fourth | 7 out |
| » Defeated Yankees (36-27), 5-1 | Fenway Park (17-9) | 30-27 | |
| » Starters: Bill Piercy vs Allen Russell | Fourth | 7 out |
| Thursday, June 23 |
| » Lost to Yankees (37-27), 6-1 | Fenway Park (17-10) | 30-28 | |
| » Starters: Rip Collins vs Hank Thormahlen | Fourth | 7 out |
| Friday, June 24 |
| » Lost to Athletics (23-38), 5-3 | Fenway Park (17-11) | 30-29 | Lost 2 |
| » Starters: Bob Hasty vs Elmer Myers | Fourth | 8 out |
| Saturday, June 25 |
| » Lost to Athletics (24-38), 3-2 | Fenway Park (17-12) | 30-30 | Lost 3 |
| » Starters: Rollie Naylor vs Herb Pennock | Fourth | 8½ out |
| » Lost to Athletics (25-38), 4-3 | Fenway Park (17-13) | 30-31 | Lost 4 |
| » Starters: Roy Moore vs Bullet Joe Bush | Fourth | 8½ out |
| Monday, June 27 |
| » Defeated Athletics (25-39), 6-5 | Fenway Park (18-13) | 31-31 | |
| » Starters: Eddie Rommel vs Allen Russell | Fourth | 9 out |
| Tuesday, June 28 |
| » Defeated Athletics (25-40), 8-1 | Fenway Park (19-13) | 32-31 | Won 2 |
| » Starters: Dave Keefe vs Elmer Myers | Fourth | 9 out |
| Wednesday, June 29 |
| » Lost to Yankees (40-28), 8-5 | Polo Grounds V (0-3) | 32-32 | |
| » Starters: Herb Pennock vs Bob Shawkey | Fourth | 10½ out |
| » Lost to Yankees (41-28), 5-3 | Polo Grounds V (0-4) | 32-33 | Lost 2 |
| » Starters: Bullet Joe Bush vs Carl Mays | Fourth | 10½ out |
| Thursday, June 30 |
| » Major-league debuts: Luke Sewell (Indians) |
| Saturday, July 2 |
| » Lost to Yankees (42-28), 5-3 | Polo Grounds V (0-5) | 32-34 | Lost 3 |
| » Starters: Allen Russell vs Rip Collins | Fifth | 10½ out |
| » Lost to Yankees (43-28), 5-1 | Polo Grounds V (0-6) | 32-35 | Lost 4 |
| » Starters: Elmer Myers vs Waite Hoyt | Fifth | 10½ out |
| Monday, July 4 |
| » Lost to Senators (39-36), 4-1 | Fenway Park (19-14) | 32-36 | Lost 5 |
| » Starters: Tom Zachary vs Sad Sam Jones | Fifth | 13 out |
| » Lost to Senators (40-36), 7-3 | Fenway Park (19-15) | 32-37 | Lost 6 |
| » Starters: Harry Courtney vs Bullet Joe Bush | Fifth | 13 out |
| Tuesday, July 5 |
| » Lost to Senators (41-36), 7-5 | Fenway Park (19-16) | 32-38 | Lost 7 |
| » Starters: George Mogridge vs Herb Pennock | Fifth | 14½ out |
| » Lost to Senators (42-36), 4-1 | Fenway Park (19-17) | 32-39 | Lost 8 |
| » Starters: Walter Johnson vs Elmer Myers | Fifth | 14½ out |
| Wednesday, July 6 |
| » Defeated Senators (42-37), 2-1 | Fenway Park (20-17) | 33-39 | |
| » Starters: George Mogridge vs Allen Russell | Fifth | 14½ out |
| » Lost to Senators (43-37), 1-0 | Fenway Park (20-18) | 33-40 | |
| » Starters: Eric Erickson vs Sad Sam Jones | Fifth | 14½ out |
| Friday, July 8 |
| » Defeated Tigers (40-39), 6-3 | Tiger Stadium (2-3) | 34-40 | |
| » Starters: Bullet Joe Bush vs Carl Holling | Fifth | 13½ out |
| Monday, July 11 |
| » Defeated Tigers (40-40), 6-1 | Tiger Stadium (3-3) | 35-40 | Won 2 |
| » Starters: Herb Pennock vs Hooks Dauss | Fifth | 13 out |
| » Defeated Tigers (40-41), 7-3 | Tiger Stadium (4-3) | 36-40 | Won 3 |
| » Starters: Sad Sam Jones vs Red Oldham | Fifth | 13 out |
| Tuesday, July 12 |
| » Lost to Indians (51-28), 7-1 | League Park II (0-4) | 36-41 | |
| » Starters: Bullet Joe Bush vs Stan Coveleski | Fifth | 15 out |
| » Lost to Indians (52-28), 6-4 | League Park II (0-5) | 36-42 | Lost 2 |
| » Starters: Elmer Myers vs Ray Caldwell | Fifth | 15 out |
| Wednesday, July 13 |
| » Lost to Indians (53-28), 4-3 | League Park II (0-6) | 36-43 | Lost 3 |
| » Starters: Allen Russell vs Duster Mails | Fifth | 16 out |
| Future Red Sox Harry Dorish is born in Swoyersville, PA. |
| Thursday, July 14 |
| » Defeated Indians (53-29), 5-2 | League Park II (1-6) | 37-43 | |
| » Starters: Sad Sam Jones vs Guy Morton | Fifth | 15 out |
| Friday, July 15 |
| » Defeated Indians (53-30), 3-2 | League Park II (2-6) | 38-43 | Won 2 |
| » Starters: Herb Pennock vs Duster Mails | Fifth | 14 out |
| Saturday, July 16 |
| » Defeated White Sox (35-48), 10-0 | Comiskey Park I (3-1) | 39-43 | Won 3 |
| » Starters: Bullet Joe Bush vs Roy Wilkinson | Fifth | 14 out |
| Sunday, July 17 |
| » Lost to White Sox (36-48), 1-0 | Comiskey Park I (3-2) | 39-44 | |
| » Starters: Elmer Myers vs Red Faber | Fifth | 14 out |
| Monday, July 18 |
| » Lost to White Sox (37-48), 5-4 | Comiskey Park I (3-3) | 39-45 | Lost 2 |
| » Starters: Sad Sam Jones vs Dickie Kerr | Fifth | 15½ out |
| » Lost to White Sox (38-48), 4-3 | Comiskey Park I (3-4) | 39-46 | Lost 3 |
| » Starters: Allen Russell vs Shovel Hodge | Fifth | 15½ out |
| Tuesday, July 19 |
| » Defeated White Sox (38-49), 1-0 | Comiskey Park I (4-4) | 40-46 | |
| » Starters: Bullet Joe Bush vs Doug McWeeny | Fifth | 15½ out |
| Wednesday, July 20 |
| » Lost to Browns (41-48), 10-9 | Sportsman's Park III (2-3) | 40-47 | |
| » Starters: Herb Pennock vs Dixie Davis | Sixth | 15½ out |
| Thursday, July 21 |
| » Lost to Browns (42-48), 8-1 | Sportsman's Park III (2-4) | 40-48 | Lost 2 |
| » Starters: Elmer Myers vs Urban Shocker | Sixth | 16½ out |
| Saturday, July 23 |
| » Lost to Browns (43-48), 5-4 | Sportsman's Park III (2-5) | 40-49 | Lost 3 |
| » Starters: Bullet Joe Bush vs Dixie Davis | Sixth | 17½ out |
| Sunday, July 24 |
| » Defeated Browns (43-49), 10-2 | Sportsman's Park III (3-5) | 41-49 | |
| » Starters: Sad Sam Jones vs Elam Vangilder | Sixth | 16½ out |
| Tuesday, July 26 |
| » Lost to Indians (59-33), 8-2 | Fenway Park (20-19) | 41-50 | |
| » Starters: Stan Coveleski vs Herb Pennock | Sixth | 17½ out |
| Wednesday, July 27 |
| » Defeated Indians (59-34), 5-4 | Fenway Park (21-19) | 42-50 | |
| » Starters: Allen Sothoron vs Bullet Joe Bush | Sixth | 16½ out |
| Thursday, July 28 |
| » Lost to Indians (60-34), 5-4 | Fenway Park (21-20) | 42-51 | |
| » Starters: Jim Bagby vs Sad Sam Jones | Sixth | 17½ out |
| Friday, July 29 |
| » Lost to Indians (61-34), 3-0 | Fenway Park (21-21) | 42-52 | Lost 2 |
| » Starters: Guy Morton vs Hank Thormahlen | Sixth | 18½ out |
| Monday, August 1 |
| » Defeated Browns (44-51), 2-0 | Fenway Park (22-21) | 43-52 | |
| » Starters: Urban Shocker vs Bullet Joe Bush | Sixth | 17½ out |
| Tuesday, August 2 |
| » Lost to Browns (45-51), 8-5 | Fenway Park (22-22) | 43-53 | |
| » Starters: Elam Vangilder vs Sad Sam Jones | Sixth | 18½ out |
| » Lost to Browns (46-51), 5-2 | Fenway Park (22-23) | 43-54 | Lost 2 |
| » Starters: Dixie Davis vs Herb Pennock | Sixth | 18½ out |
| Wednesday, August 3 |
| » Defeated White Sox (43-55), 3-2 | Fenway Park (23-23) | 44-54 | |
| » Starters: Red Faber vs Elmer Myers | Sixth | 18 out |
| Thursday, August 4 |
| » Lost to White Sox (44-55), 5-4 | Fenway Park (23-24) | 44-55 | |
| » Starters: Jack Wieneke vs Hank Thormahlen | Sixth | 17 out |
| Friday, August 5 |
| » Defeated White Sox (44-56), 10-1 | Fenway Park (24-24) | 45-55 | |
| » Starters: Dominic Mulrenan vs Bullet Joe Bush | Sixth | 17 out |
| Saturday, August 6 |
| » Defeated White Sox (44-57), 9-4 | Fenway Park (25-24) | 46-55 | Won 2 |
| » Starters: Roy Wilkinson vs Herb Pennock | Sixth | 16 out |
| Monday, August 8 |
| » Defeated Tigers (50-55), 6-1 | Fenway Park (26-24) | 47-55 | Won 3 |
| » Starters: Dutch Leonard vs Elmer Myers | Sixth | 17½ out |
| Tuesday, August 9 |
| » Defeated Tigers (50-56), 8-7 | Fenway Park (27-24) | 48-55 | Won 4 |
| » Starters: Hooks Dauss vs Bullet Joe Bush | Fifth | 16 out |
| » Defeated Tigers (50-57), 4-1 | Fenway Park (28-24) | 49-55 | Won 5 |
| » Starters: Carl Holling vs Sad Sam Jones | Fifth | 16 out |
| Wednesday, August 10 |
| » Lost to Tigers (51-57), 8-4 | Fenway Park (28-25) | 49-56 | |
| » Starters: Red Oldham vs Herb Pennock | Sixth | 15½ out |
| Saturday, August 13 |
| » Lost to Senators (60-52), 6-1 | Griffith Stadium (4-4) | 49-57 | Lost 2 |
| » Starters: Elmer Myers vs Walter Johnson | Sixth | 17½ out |
| Sunday, August 14 |
| » Defeated Senators (60-53), 2-0 | Griffith Stadium (5-4) | 50-57 | |
| » Starters: Sad Sam Jones vs Eric Erickson | Fifth | 16½ out |
| Thursday, August 18 |
| » Defeated Tigers (52-62), 6-5 | Tiger Stadium (5-3) | 51-57 | Won 2 |
| » Starters: Bullet Joe Bush vs Red Oldham | Fifth | 15½ out |
| » Defeated Tigers (52-63), 5-0 | Tiger Stadium (6-3) | 52-57 | Won 3 |
| » Starters: Sad Sam Jones vs Carl Holling | Fifth | 15½ out |
| Friday, August 19 |
| » Defeated Tigers (52-64), 12-8 | Tiger Stadium (7-3) | 53-57 | Won 4 |
| » Starters: Bullet Joe Bush vs Hooks Dauss | Fifth | 16 out |
| » Lost to Tigers (53-64), 10-0 | Tiger Stadium (7-4) | 53-58 | |
| » Starters: Elmer Myers vs Bert Cole | Fifth | 16 out |
| Saturday, August 20 |
| » Lost to Indians (71-43), 7-3 | League Park II (2-7) | 53-59 | Lost 2 |
| » Starters: Herb Pennock vs Stan Coveleski | Fifth | 17 out |
| Sunday, August 21 |
| » Lost to Indians (72-43), 4-0 | League Park II (2-8) | 53-60 | Lost 3 |
| » Starters: Allen Russell vs Allen Sothoron | Fifth | 18 out |
| Monday, August 22 |
| » Defeated Indians (72-44), 6-5 | League Park II (3-8) | 54-60 | |
| » Starters: Sad Sam Jones vs Guy Morton | Fifth | 17 out |
| Tuesday, August 23 |
| » Defeated Browns (58-60), 15-2 | Sportsman's Park III (4-5) | 55-60 | Won 2 |
| » Starters: Bullet Joe Bush vs Dixie Davis | Fifth | 16 out |
| Wednesday, August 24 |
| » Lost to Browns (59-60), 12-11 | Sportsman's Park III (4-6) | 55-61 | |
| » Starters: Elmer Myers vs Urban Shocker | Sixth | 16½ out |
| Thursday, August 25 |
| » Lost to Browns (60-60), 7-2 | Sportsman's Park III (4-7) | 55-62 | Lost 2 |
| » Starters: Herb Pennock vs Elam Vangilder | Sixth | 17 out |
| Friday, August 26 |
| » Defeated White Sox (52-68), 5-4 | Comiskey Park I (5-4) | 56-62 | |
| » Starters: Sad Sam Jones vs Shovel Hodge | Fifth | 17 out |
| Saturday, August 27 |
| » Defeated White Sox (52-69), 6-5 | Comiskey Park I (6-4) | 57-62 | Won 2 |
| » Starters: Allen Russell vs Red Faber | Fifth | 17 out |
| Sunday, August 28 |
| » Defeated White Sox (52-70), 6-5 | Comiskey Park I (7-4) | 58-62 | Won 3 |
| » Starters: Bullet Joe Bush vs Dickie Kerr | Fifth | 17 out |
| Thursday, September 1 |
| » Lost to Athletics (44-78), 4-2 | Fenway Park (28-26) | 58-63 | |
| » Starters: Eddie Rommel vs Sad Sam Jones | Fifth | 18 out |
| Friday, September 2 |
| » Defeated Athletics (44-79), 4-3 | Fenway Park (29-26) | 59-63 | |
| » Starters: Bob Hasty vs Bullet Joe Bush | Fifth | 18 out |
| Saturday, September 3 |
| » Defeated Athletics (44-80), 11-10 | Fenway Park (30-26) | 60-63 | Won 2 |
| » Starters: Dave Keefe vs Elmer Myers | Fifth | 18 out |
| Monday, September 5 |
| » Lost to Yankees (80-46), 8-0 | Fenway Park (30-27) | 60-64 | |
| » Starters: Bob Shawkey vs Sad Sam Jones | Fifth | 18 out |
| » Defeated Yankees (80-47), 8-2 | Fenway Park (31-27) | 61-64 | |
| » Starters: Rip Collins vs Benn Karr | Fifth | 18 out |
| Tuesday, September 6 |
| » Defeated Yankees (80-48), 2-1 | Fenway Park (32-27) | 62-64 | Won 2 |
| » Starters: Waite Hoyt vs Bullet Joe Bush | Fifth | 17 out |
| Wednesday, September 7 |
| » Lost to Yankees (81-48), 6-2 | Polo Grounds V (0-7) | 62-65 | |
| » Starters: Allen Russell vs Carl Mays | Fifth | 19 out |
| » Lost to Yankees (82-48), 7-2 | Polo Grounds V (0-8) | 62-66 | Lost 2 |
| » Starters: Herb Pennock vs Harry Harper | Fifth | 19 out |
| Friday, September 9 |
| » Defeated Senators (66-69), 5-1 | Griffith Stadium (6-4) | 63-66 | |
| » Starters: Sad Sam Jones vs George Mogridge | Fifth | 18½ out |
| Saturday, September 10 |
| » Lost to Senators (67-69), 5-3 | Griffith Stadium (6-5) | 63-67 | |
| » Starters: Allen Russell vs Walter Johnson | Fifth | 19½ out |
| Sunday, September 11 |
| » Defeated Yankees (84-50), 3-1 | Polo Grounds V (1-8) | 64-67 | |
| » Starters: Bullet Joe Bush vs Waite Hoyt | Fifth | 19½ out |
| » Lost to Yankees (85-50), 5-1 | Polo Grounds V (1-9) | 64-68 | |
| » Starters: Benn Karr vs Bill Piercy | Fifth | 19½ out |
| Tuesday, September 13 |
| » Lost to Tigers (67-73), 7-2 | Fenway Park (32-28) | 64-69 | Lost 2 |
| » Starters: Dutch Leonard vs Sad Sam Jones | Fifth | 19½ out |
| Wednesday, September 14 |
| » Defeated Tigers (67-74), 1-0 | Fenway Park (33-28) | 65-69 | |
| » Starters: Red Oldham vs Herb Pennock | Fifth | 19½ out |
| Thursday, September 15 |
| » Lost to Tigers (68-74), 5-1 | Fenway Park (33-29) | 65-70 | |
| » Starters: Bert Cole vs Benn Karr | Fifth | 21 out |
| Friday, September 16 |
| » Defeated White Sox (58-81), 10-4 | Fenway Park (34-29) | 66-70 | |
| » Starters: Roy Wilkinson vs Bullet Joe Bush | Fifth | 20½ out |
| Saturday, September 17 |
| » Defeated White Sox (58-82), 6-3 | Fenway Park (35-29) | 67-70 | Won 2 |
| » Starters: Dickie Kerr vs Sad Sam Jones | Fourth | 20½ out |
| Monday, September 19 |
| » Defeated White Sox (58-83), 6-2 | Fenway Park (36-29) | 68-70 | Won 3 |
| » Starters: Lee Thompson vs Bullet Joe Bush | Fourth | 19 out |
| » Defeated White Sox (58-84), 8-5 | Fenway Park (37-29) | 69-70 | Won 4 |
| » Starters: Sarge Connally vs Benn Karr | Fourth | 19 out |
| Tuesday, September 20 |
| » Defeated Indians (90-54), 7-4 | Fenway Park (38-29) | 70-70 | Won 5 |
| » Starters: George Uhle vs Herb Pennock | Fourth | 18½ out |
| Wednesday, September 21 |
| » Lost to Indians (91-54), 5-1 | Fenway Park (38-30) | 70-71 | |
| » Starters: Ray Caldwell vs Sad Sam Jones | Fifth | 19 out |
| Thursday, September 22 |
| » Lost to Indians (92-54), 9-8 | Fenway Park (38-31) | 70-72 | Lost 2 |
| » Starters: Allen Sothoron vs Allen Russell | Fifth | 20 out |
| Friday, September 23 |
| » Lost to Browns (77-71), 10-2 | Fenway Park (38-32) | 70-73 | Lost 3 |
| » Starters: Urban Shocker vs Bullet Joe Bush | Fifth | 20½ out |
| » Defeated Browns (77-72), 10-5 | Fenway Park (39-32) | 71-73 | |
| » Starters: Elam Vangilder vs Benn Karr | Fifth | 20½ out |
| Saturday, September 24 |
| » Defeated Browns (77-73), 2-1 | Fenway Park (40-32) | 72-73 | Won 2 |
| » Starters: Dixie Davis vs Herb Pennock | Fifth | 20 out |
| » Lost to Browns (78-73), 11-0 | Fenway Park (40-33) | 72-74 | |
| » Starters: Dixie Davis vs Sad Sam Jones | Fifth | 20 out |
| Future Red Sox Clyde Vollmer is born in Cincinnati, OH. |
| Tuesday, September 27 |
| » Lost to Athletics (53-94), 9-5 | Shibe Park (4-5) | 72-75 | Lost 2 |
| » Starters: Benn Karr vs Eddie Rommel | Fifth | 20½ out |
| » Defeated Athletics (53-95), 8-1 | Shibe Park (5-5) | 73-75 | |
| » Starters: Bullet Joe Bush vs Jim Sullivan | Fifth | 20½ out |
| Wednesday, September 28 |
| » Defeated Athletics (53-96), 5-4 | Shibe Park (6-5) | 74-75 | Won 2 |
| » Starters: Herb Pennock vs Rollie Naylor | Fifth | 20 out |
| Thursday, September 29 |
| » Defeated Senators (76-73), 5-2 | Fenway Park (41-33) | 75-75 | Won 3 |
| » Starters: Walter Johnson vs Sad Sam Jones | Fifth | 20 out |
| Friday, September 30 |
| » Lost to Senators (77-73), 6-4 | Fenway Park (41-34) | 75-76 | |
| » Starters: George Mogridge vs Bullet Joe Bush | Fifth | 20½ out |
| Saturday, October 1 |
| » Lost to Senators (78-73), 7-2 | Fenway Park (41-35) | 75-77 | Lost 2 |
| » Starters: Tom Zachary vs Herb Pennock | Fifth | 22½ out |
| » Lost to Senators (79-73), 6-1 | Fenway Park (41-36) | 75-78 | Lost 3 |
| » Starters: Eric Erickson vs Benn Karr | Fifth | 22½ out |
| Sunday, October 2 |
| » Lost to Yankees (98-55), 7-6 | Polo Grounds V (1-10) | 75-79 | Lost 4 |
| » Starters: Curt Fullerton vs Bob Shawkey | Fifth | 23½ out |
| Sunday, October 16 |
| Future Red Sox Matt Batts is born in San Antonio, TX. |
| Monday, October 24 |
| Former Red Sox Jimmy Barrett dies in Detroit, MI at the age of 47. |
Game information provided by Retrosheet (www.retrosheet.org) |