| Tuesday, February 8 |
| Future Indian Hoot Evers is born in St. Louis, MO. |
| Saturday, March 5 |
| Future Indian Elmer Valo is born in Ribnik, Czechoslovakia. |
| Monday, March 14 |
| Future Indian Bill Kennedy is born in Carnesville, GA. |
| Wednesday, April 13 |
| » Lost to Browns (1-0), 4-2 | Sportsman's Park III (0-1) | 0-1 | |
| » Starters: Stan Coveleski vs Urban Shocker | Third | 1 out |
| » Major-league debuts: Riggs Stephenson (Indians) |
| Thursday, April 14 |
| » Defeated Browns (1-1), 12-9 | Sportsman's Park III (1-1) | 1-1 | |
| » Starters: Duster Mails vs Allen Sothoron | Second | ½ out |
| » Major-league debuts: Jesse Petty (Indians) |
| Friday, April 15 |
| » Defeated Browns (1-2), 10-4 | Sportsman's Park III (2-1) | 2-1 | Won 2 |
| » Starters: Jim Bagby vs Dixie Davis | First | -- |
| Saturday, April 16 |
| » Lost to Browns (2-2), 7-6 | Sportsman's Park III (2-2) | 2-2 | |
| » Starters: George Uhle vs Ray Kolp | Third | ½ out |
| » Major-league debuts: Ray Kolp (Browns) |
| Tuesday, April 19 |
| » Defeated Tigers (1-2), 12-3 | Tiger Stadium (1-0) | 3-2 | |
| » Starters: Stan Coveleski vs Carl Holling | Third | ½ out |
| » Major-league debuts: Bert Cole and Carl Holling (Tigers) |
| Wednesday, April 20 |
| » Lost to Tigers (2-2), 9-6 | Tiger Stadium (1-1) | 3-3 | |
| » Starters: Duster Mails vs Red Oldham | Fifth | 1½ out |
| » Major-league debuts: Lefty Stewart (Tigers) Tex Jeanes (Indians) |
| Thursday, April 21 |
| » Defeated Browns (4-3), 4-3 | League Park II (1-0) | 4-3 | |
| » Starters: Urban Shocker vs Jim Bagby | Third | 1½ out |
| Friday, April 22 |
| » Defeated Browns (4-4), 8-7 | League Park II (2-0) | 5-3 | Won 2 |
| » Starters: Ray Kolp vs Ray Caldwell | Second | ½ out |
| Saturday, April 23 |
| » Defeated Browns (4-5), 6-2 | League Park II (3-0) | 6-3 | Won 3 |
| » Starters: Dixie Davis vs Stan Coveleski | Second | 1 out |
| Sunday, April 24 |
| » Defeated Browns (4-6), 6-5 | League Park II (4-0) | 7-3 | Won 4 |
| » Starters: Bill Bayne vs George Uhle | First | -- |
| Monday, April 25 |
| » Defeated Tigers (3-5), 5-3 | League Park II (5-0) | 8-3 | Won 5 |
| » Starters: Suds Sutherland vs Jim Bagby | First | -- |
| Tuesday, April 26 |
| » Defeated Tigers (3-6), 9-8 | League Park II (6-0) | 9-3 | Won 6 |
| » Starters: Bert Cole vs Ray Caldwell | First | -- |
| Wednesday, April 27 |
| » Lost to Tigers (4-6), 5-2 | League Park II (6-1) | 9-4 | |
| » Starters: Carl Holling vs Stan Coveleski | Second | ½ out |
| Thursday, April 28 |
| » Defeated Tigers (4-7), 18-5 | League Park II (7-1) | 10-4 | |
| » Starters: Dutch Leonard vs George Uhle | First | -- |
| Friday, April 29 |
| » Lost to White Sox (4-5), 1-0 | Comiskey Park I (0-1) | 10-5 | |
| » Starters: Jim Bagby vs Red Faber | Second | 1 out |
| Saturday, April 30 |
| » Defeated White Sox (4-6), 4-3 | Comiskey Park I (1-1) | 11-5 | |
| » Starters: Duster Mails vs Dickie Kerr | Second | 1 out |
| Sunday, May 1 |
| » Defeated White Sox (4-7), 5-1 | Comiskey Park I (2-1) | 12-5 | Won 2 |
| » Starters: Stan Coveleski vs Bugs Bennett | First | -- |
| Thursday, May 5 |
| » Lost to White Sox (5-9), 4-0 | League Park II (7-2) | 12-6 | |
| » Starters: Red Faber vs Jim Bagby | First | -- |
| Friday, May 6 |
| » Defeated White Sox (5-10), 8-0 | League Park II (8-2) | 13-6 | |
| » Starters: Bugs Bennett vs Stan Coveleski | First | -- |
| Saturday, May 7 |
| » Defeated White Sox (5-11), 8-0 | League Park II (9-2) | 14-6 | Won 2 |
| » Starters: Roy Wilkinson vs Duster Mails | First | -- |
| Sunday, May 8 |
| » Defeated White Sox (5-12), 17-3 | League Park II (10-2) | 15-6 | Won 3 |
| » Starters: Dickie Kerr vs George Uhle | First | -- |
| Tuesday, May 10 |
| » Lost to Senators (12-9), 9-7 | League Park II (10-3) | 15-7 | |
| » Starters: Jim Shaw vs Jim Bagby | First | -- |
| Wednesday, May 11 |
| » Defeated Senators (12-10), 14-1 | League Park II (11-3) | 16-7 | |
| » Starters: Walter Johnson vs Stan Coveleski | First | -- |
| Thursday, May 12 |
| » Lost to Senators (13-10), 4-1 | League Park II (11-4) | 16-8 | |
| » Starters: Eric Erickson vs Duster Mails | First | -- |
| Friday, May 13 |
| » Lost to Senators (14-10), 4-2 | League Park II (11-5) | 16-9 | Lost 2 |
| » Starters: George Mogridge vs George Uhle | First | -- |
| Saturday, May 14 |
| » Lost to Yankees (13-9), 6-4 | League Park II (11-6) | 16-10 | Lost 3 |
| » Starters: Jack Quinn vs Jim Bagby | First | -- |
| Sunday, May 15 |
| » Lost to Yankees (14-9), 8-2 | League Park II (11-7) | 16-11 | Lost 4 |
| » Starters: Waite Hoyt vs Stan Coveleski | Second | 2 out |
| Monday, May 16 |
| » Lost to Yankees (15-9), 6-3 | League Park II (11-8) | 16-12 | Lost 5 |
| » Starters: Carl Mays vs Duster Mails | Second | 2 out |
| Tuesday, May 17 |
| » Defeated Yankees (15-10), 4-2 | League Park II (12-8) | 17-12 | |
| » Starters: Alex Ferguson vs George Uhle | Second | 2 out |
| Wednesday, May 18 |
| » Defeated Athletics (8-18), 4-2 | League Park II (13-8) | 18-12 | Won 2 |
| » Starters: Eddie Rommel vs Stan Coveleski | First | -- |
| Thursday, May 19 |
| » Defeated Athletics (8-19), 4-3 | League Park II (14-8) | 19-12 | Won 3 |
| » Starters: Scott Perry vs Jim Bagby | First | -- |
| Friday, May 20 |
| » Defeated Athletics (8-20), 16-3 | League Park II (15-8) | 20-12 | Won 4 |
| » Starters: Slim Harriss vs Duster Mails | First | -- |
| Future Indian Hal Newhouser is born in Detroit, MI. |
| Saturday, May 21 |
| » Lost to Athletics (9-20), 11-8 | League Park II (15-9) | 20-13 | |
| » Starters: Dave Keefe vs George Uhle | First | -- |
| Sunday, May 22 |
| » Defeated Red Sox (13-14), 5-0 | League Park II (16-9) | 21-13 | |
| » Starters: Sad Sam Jones vs Stan Coveleski | First | -- |
| Monday, May 23 |
| » Defeated Red Sox (13-15), 4-1 | League Park II (17-9) | 22-13 | Won 2 |
| » Starters: Hank Thormahlen vs Jim Bagby | First | -- |
| Wednesday, May 25 |
| » Defeated Red Sox (13-16), 3-2 | League Park II (18-9) | 23-13 | Won 3 |
| » Starters: Herb Pennock vs George Uhle | First | -- |
| Thursday, May 26 |
| » Defeated Browns (17-19), 12-5 | Sportsman's Park III (3-2) | 24-13 | Won 4 |
| » Starters: Stan Coveleski vs Emilio Palmero | First | -- |
| Friday, May 27 |
| » Defeated Browns (17-20), 10-8 | Sportsman's Park III (4-2) | 25-13 | Won 5 |
| » Starters: Jim Bagby vs Dixie Davis | First | -- |
| Saturday, May 28 |
| » Defeated Browns (17-21), 12-6 | Sportsman's Park III (5-2) | 26-13 | Won 6 |
| » Starters: Duster Mails vs Bernie Boland | First | -- |
| Sunday, May 29 |
| » Defeated Browns (17-22), 11-9 | Sportsman's Park III (6-2) | 27-13 | Won 7 |
| » Starters: George Uhle vs Urban Shocker | First | -- |
| Future Indian Ferris Fain is born in San Antonio, TX. |
| Monday, May 30 |
| » Defeated Tigers (23-21), 6-5 | Tiger Stadium (2-1) | 28-13 | Won 8 |
| » Starters: Stan Coveleski vs Howard Ehmke | First | -- |
| » Lost to Tigers (24-21), 9-5 | Tiger Stadium (2-2) | 28-14 | |
| » Starters: Jim Bagby vs Jim Middleton | First | -- |
| Tuesday, May 31 |
| » Defeated Tigers (24-22), 7-4 | Tiger Stadium (3-2) | 29-14 | |
| » Starters: Duster Mails vs Hooks Dauss | First | -- |
| Thursday, June 2 |
| » Defeated Red Sox (17-21), 8-4 | Fenway Park (1-0) | 30-14 | Won 2 |
| » Starters: George Uhle vs Allen Sothoron | First | -- |
| Friday, June 3 |
| » Lost to Red Sox (18-21), 7-6 | Fenway Park (1-1) | 30-15 | |
| » Starters: Stan Coveleski vs Allen Russell | First | -- |
| Saturday, June 4 |
| » Lost to Red Sox (19-21), 6-0 | Fenway Park (1-2) | 30-16 | Lost 2 |
| » Starters: Jim Bagby vs Sad Sam Jones | First | -- |
| Monday, June 6 |
| » Lost to Red Sox (20-21), 7-6 | Fenway Park (1-3) | 30-17 | Lost 3 |
| » Starters: Duster Mails vs Herb Pennock | First | -- |
| Tuesday, June 7 |
| » Lost to Yankees (28-19), 9-2 | Polo Grounds V (0-1) | 30-18 | Lost 4 |
| » Starters: Stan Coveleski vs Bob Shawkey | First | -- |
| Wednesday, June 8 |
| » Lost to Yankees (29-19), 4-3 | Polo Grounds V (0-2) | 30-19 | Lost 5 |
| » Starters: George Uhle vs Waite Hoyt | First | -- |
| Thursday, June 9 |
| » Defeated Yankees (29-20), 14-4 | Polo Grounds V (1-2) | 31-19 | |
| » Starters: Ray Caldwell vs Jack Quinn | First | -- |
| Friday, June 10 |
| » Defeated Yankees (29-21), 8-6 | Polo Grounds V (2-2) | 32-19 | Won 2 |
| » Starters: Jim Bagby vs Carl Mays | First | -- |
| Saturday, June 11 |
| » Defeated Senators (28-25), 7-3 | Griffith Stadium (1-0) | 33-19 | Won 3 |
| » Starters: Stan Coveleski vs Tom Zachary | First | -- |
| Sunday, June 12 |
| » Lost to Senators (29-25), 10-3 | Griffith Stadium (1-1) | 33-20 | |
| » Starters: George Uhle vs George Mogridge | First | -- |
| Monday, June 13 |
| » Defeated Senators (29-26), 10-6 | Griffith Stadium (2-1) | 34-20 | |
| » Starters: Ray Caldwell vs Eric Erickson | First | -- |
| Tuesday, June 14 |
| » Lost to Senators (30-26), 8-7 | Griffith Stadium (2-2) | 34-21 | |
| » Starters: Jim Bagby vs Jim Shaw | First | -- |
| Wednesday, June 15 |
| » Defeated Athletics (18-35), 6-5 | Shibe Park (1-0) | 35-21 | |
| » Starters: Stan Coveleski vs Bob Hasty | First | -- |
| Thursday, June 16 |
| » Defeated Athletics (18-36), 3-2 | Shibe Park (2-0) | 36-21 | Won 2 |
| » Starters: George Uhle vs Rollie Naylor | First | -- |
| Friday, June 17 |
| Future Indian Dave Pope is born in Talladega, AL. |
| Saturday, June 18 |
| » Lost to Athletics (19-36), 8-4 | Shibe Park (2-1) | 36-22 | |
| » Starters: Jim Bagby vs Slim Harriss | First | -- |
| Sunday, June 19 |
| » Defeated Tigers (29-34), 8-7 | League Park II (19-9) | 37-22 | |
| » Starters: Dutch Leonard vs Stan Coveleski | First | -- |
| Tuesday, June 21 |
| » Defeated White Sox (25-31), 6-3 | Comiskey Park I (3-1) | 38-22 | Won 2 |
| » Starters: George Uhle vs Doug McWeeny | First | -- |
| Wednesday, June 22 |
| » Defeated White Sox (25-32), 3-2 | Comiskey Park I (4-1) | 39-22 | Won 3 |
| » Starters: Jim Bagby vs Red Faber | First | -- |
| Thursday, June 23 |
| » Lost to White Sox (26-32), 6-0 | Comiskey Park I (4-2) | 39-23 | |
| » Starters: Stan Coveleski vs Dickie Kerr | First | -- |
| Friday, June 24 |
| » Defeated White Sox (26-33), 4-2 | Comiskey Park I (5-2) | 40-23 | |
| » Starters: Duster Mails vs Roy Wilkinson | First | -- |
| Saturday, June 25 |
| » Lost to Browns (28-35), 10-5 | League Park II (19-10) | 40-24 | |
| » Starters: Ray Kolp vs George Uhle | First | -- |
| Sunday, June 26 |
| » Defeated Browns (28-36), 15-1 | League Park II (20-10) | 41-24 | |
| » Starters: Emilio Palmero vs Jim Bagby | First | -- |
| Monday, June 27 |
| » Defeated Browns (28-37), 4-2 | League Park II (21-10) | 42-24 | Won 2 |
| » Starters: Elam Vangilder vs Duster Mails | First | -- |
| Tuesday, June 28 |
| » Defeated Browns (28-38), 12-4 | League Park II (22-10) | 43-24 | Won 3 |
| » Starters: Joe DeBerry vs Stan Coveleski | First | -- |
| Wednesday, June 29 |
| » Defeated Tigers (33-36), 9-6 | League Park II (23-10) | 44-24 | Won 4 |
| » Starters: Dutch Leonard vs George Uhle | First | -- |
| Thursday, June 30 |
| » Lost to Tigers (34-36), 6-3 | League Park II (23-11) | 44-25 | |
| » Starters: Hooks Dauss vs Jim Bagby | First | -- |
| » Major-league debuts: Luke Sewell (Indians) |
| Saturday, July 2 |
| » Lost to Tigers (35-36), 6-3 | League Park II (23-12) | 44-26 | Lost 2 |
| » Starters: Howard Ehmke vs Duster Mails | First | -- |
| Sunday, July 3 |
| » Defeated Tigers (35-37), 9-5 | League Park II (24-12) | 45-26 | |
| » Starters: Jim Middleton vs Stan Coveleski | First | -- |
| Monday, July 4 |
| » Defeated White Sox (29-40), 6-4 | League Park II (25-12) | 46-26 | Won 2 |
| » Starters: Cy Twombly vs George Uhle | First | -- |
| » Defeated White Sox (29-41), 11-10 | League Park II (26-12) | 47-26 | Won 3 |
| » Starters: Dickie Kerr vs Jim Bagby | First | -- |
| Tuesday, July 5 |
| » Defeated White Sox (29-42), 16-4 | League Park II (27-12) | 48-26 | Won 4 |
| » Starters: Dominic Mulrenan vs Allen Sothoron | First | -- |
| Thursday, July 7 |
| » Lost to Athletics (30-44), 5-3 | League Park II (27-13) | 48-27 | |
| » Starters: Roy Moore vs Stan Coveleski | First | -- |
| Saturday, July 9 |
| » Lost to Athletics (31-44), 4-2 | League Park II (27-14) | 48-28 | Lost 2 |
| » Starters: Slim Harriss vs George Uhle | First | -- |
| Sunday, July 10 |
| » Defeated Athletics (31-45), 10-0 | League Park II (28-14) | 49-28 | |
| » Starters: Eddie Rommel vs Duster Mails | First | -- |
| » Defeated Athletics (31-46), 1-0 | League Park II (29-14) | 50-28 | Won 2 |
| » Starters: Bob Hasty vs Guy Morton | First | -- |
| Tuesday, July 12 |
| » Defeated Red Sox (36-41), 7-1 | League Park II (30-14) | 51-28 | Won 3 |
| » Starters: Bullet Joe Bush vs Stan Coveleski | First | -- |
| » Defeated Red Sox (36-42), 6-4 | League Park II (31-14) | 52-28 | Won 4 |
| » Starters: Elmer Myers vs Ray Caldwell | First | -- |
| Wednesday, July 13 |
| » Defeated Red Sox (36-43), 4-3 | League Park II (32-14) | 53-28 | Won 5 |
| » Starters: Allen Russell vs Duster Mails | First | -- |
| Thursday, July 14 |
| » Lost to Red Sox (37-43), 5-2 | League Park II (32-15) | 53-29 | |
| » Starters: Sad Sam Jones vs Guy Morton | First | -- |
| Friday, July 15 |
| » Lost to Red Sox (38-43), 3-2 | League Park II (32-16) | 53-30 | Lost 2 |
| » Starters: Herb Pennock vs Duster Mails | First | -- |
| Saturday, July 16 |
| » Defeated Senators (46-43), 8-4 | League Park II (33-16) | 54-30 | |
| » Starters: Harry Courtney vs Stan Coveleski | First | -- |
| Sunday, July 17 |
| » Lost to Senators (47-43), 13-2 | League Park II (33-17) | 54-31 | |
| » Starters: Tom Zachary vs Ray Caldwell | First | -- |
| Monday, July 18 |
| » Defeated Senators (47-44), 3-2 | League Park II (34-17) | 55-31 | |
| » Starters: George Mogridge vs Allen Sothoron | First | -- |
| Tuesday, July 19 |
| » Defeated Senators (47-45), 6-4 | League Park II (35-17) | 56-31 | Won 2 |
| » Starters: Eric Erickson vs Duster Mails | First | -- |
| Wednesday, July 20 |
| » Lost to Yankees (55-31), 7-1 | League Park II (35-18) | 56-32 | |
| » Starters: Bob Shawkey vs Stan Coveleski | Second | 1 out |
| Thursday, July 21 |
| » Defeated Yankees (55-32), 17-8 | League Park II (36-18) | 57-32 | |
| » Starters: Carl Mays vs Ray Caldwell | First | -- |
| Saturday, July 23 |
| » Defeated Yankees (55-33), 3-0 | League Park II (37-18) | 58-32 | Won 2 |
| » Starters: Waite Hoyt vs Allen Sothoron | First | -- |
| Sunday, July 24 |
| » Lost to Yankees (56-33), 7-3 | League Park II (37-19) | 58-33 | |
| » Starters: Bob Shawkey vs Duster Mails | First | -- |
| Tuesday, July 26 |
| » Defeated Red Sox (41-50), 8-2 | Fenway Park (2-3) | 59-33 | |
| » Starters: Stan Coveleski vs Herb Pennock | First | -- |
| Wednesday, July 27 |
| » Lost to Red Sox (42-50), 5-4 | Fenway Park (2-4) | 59-34 | |
| » Starters: Allen Sothoron vs Bullet Joe Bush | First | -- |
| Thursday, July 28 |
| » Defeated Red Sox (42-51), 5-4 | Fenway Park (3-4) | 60-34 | |
| » Starters: Jim Bagby vs Sad Sam Jones | First | -- |
| Friday, July 29 |
| » Defeated Red Sox (42-52), 3-0 | Fenway Park (4-4) | 61-34 | Won 2 |
| » Starters: Guy Morton vs Hank Thormahlen | First | -- |
| Saturday, July 30 |
| » Defeated Yankees (57-35), 16-1 | Polo Grounds V (3-2) | 62-34 | Won 3 |
| » Starters: Stan Coveleski vs Bob Shawkey | First | -- |
| Sunday, July 31 |
| » Lost to Yankees (58-35), 12-2 | Polo Grounds V (3-3) | 62-35 | |
| » Starters: Allen Sothoron vs Carl Mays | First | -- |
| Monday, August 1 |
| » Lost to Yankees (59-35), 5-2 | Polo Grounds V (3-4) | 62-36 | Lost 2 |
| » Starters: Jim Bagby vs Waite Hoyt | First | -- |
| Thursday, August 4 |
| » Lost to Senators (56-48), 3-1 | Griffith Stadium (2-3) | 62-37 | Lost 3 |
| » Starters: Stan Coveleski vs Walter Johnson | Second | 2½ out |
| » Lost to Senators (57-48), 3-1 | Griffith Stadium (2-4) | 62-38 | Lost 4 |
| » Starters: Guy Morton vs Eric Erickson | Second | 2½ out |
| Friday, August 5 |
| » Lost to Senators (58-48), 4-1 | Griffith Stadium (2-5) | 62-39 | Lost 5 |
| » Starters: Jim Bagby vs George Mogridge | Second | 2½ out |
| Saturday, August 6 |
| » Defeated Senators (58-49), 3-1 | Griffith Stadium (3-5) | 63-39 | |
| » Starters: George Uhle vs Tom Zachary | Second | 2½ out |
| Sunday, August 7 |
| » Defeated Athletics (38-64), 4-3 | League Park II (38-19) | 64-39 | Won 2 |
| » Starters: Bob Hasty vs Guy Morton | Second | 2½ out |
| Monday, August 8 |
| » Defeated Athletics (38-65), 4-3 | Shibe Park (3-1) | 65-39 | Won 3 |
| » Starters: Stan Coveleski vs Eddie Rommel | First | -- |
| » Defeated Athletics (38-66), 7-6 | Shibe Park (4-1) | 66-39 | Won 4 |
| » Starters: Jim Bagby vs Rollie Naylor | First | -- |
| Tuesday, August 9 |
| » Lost to Athletics (39-66), 4-3 | Shibe Park (4-2) | 66-40 | |
| » Starters: Ray Caldwell vs Harvey Freeman | First | -- |
| Wednesday, August 10 |
| » Lost to Athletics (40-66), 9-5 | Shibe Park (4-3) | 66-41 | Lost 2 |
| » Starters: George Uhle vs Roy Moore | Second | 2½ out |
| Friday, August 12 |
| » Defeated White Sox (46-61), 6-1 | League Park II (39-19) | 67-41 | |
| » Starters: Red Faber vs Stan Coveleski | First | -- |
| Saturday, August 13 |
| » Defeated White Sox (46-62), 6-1 | League Park II (40-19) | 68-41 | Won 2 |
| » Starters: Roy Wilkinson vs Allen Sothoron | First | -- |
| Sunday, August 14 |
| » Lost to White Sox (47-62), 4-1 | League Park II (40-20) | 68-42 | |
| » Starters: Red Faber vs George Uhle | Second | 2 out |
| Monday, August 15 |
| » Defeated White Sox (47-63), 3-2 | League Park II (41-20) | 69-42 | |
| » Starters: Doug McWeeny vs Guy Morton | Second | 2½ out |
| Wednesday, August 17 |
| » Defeated Athletics (41-70), 15-8 | League Park II (42-20) | 70-42 | Won 2 |
| » Starters: Roy Moore vs Stan Coveleski | Second | 2½ out |
| Thursday, August 18 |
| » Lost to Athletics (42-70), 6-4 | League Park II (42-21) | 70-43 | |
| » Starters: Bob Hasty vs Allen Sothoron | Second | 2½ out |
| Saturday, August 20 |
| » Defeated Red Sox (53-59), 7-3 | League Park II (43-21) | 71-43 | |
| » Starters: Herb Pennock vs Stan Coveleski | First | -- |
| Sunday, August 21 |
| » Defeated Red Sox (53-60), 4-0 | League Park II (44-21) | 72-43 | Won 2 |
| » Starters: Allen Russell vs Allen Sothoron | First | -- |
| Monday, August 22 |
| » Lost to Red Sox (54-60), 6-5 | League Park II (44-22) | 72-44 | |
| » Starters: Sad Sam Jones vs Guy Morton | First | -- |
| Tuesday, August 23 |
| » Lost to Yankees (70-44), 6-1 | League Park II (44-23) | 72-45 | Lost 2 |
| » Starters: Jack Quinn vs Ray Caldwell | First | -- |
| Future Indian Dale Mitchell is born in Colony, OK. |
| Wednesday, August 24 |
| » Lost to Yankees (71-44), 3-2 | League Park II (44-24) | 72-46 | Lost 3 |
| » Starters: Waite Hoyt vs Stan Coveleski | Second | 1½ out |
| Thursday, August 25 |
| » Defeated Yankees (71-45), 15-1 | League Park II (45-24) | 73-46 | |
| » Starters: Bob Shawkey vs Allen Sothoron | First | -- |
| Friday, August 26 |
| » Defeated Senators (65-58), 6-3 | League Park II (46-24) | 74-46 | Won 2 |
| » Starters: Eric Erickson vs Duster Mails | First | -- |
| Saturday, August 27 |
| » Defeated Senators (65-59), 6-2 | League Park II (47-24) | 75-46 | Won 3 |
| » Starters: Tom Zachary vs George Uhle | First | -- |
| Sunday, August 28 |
| » Defeated Senators (65-60), 3-2 | League Park II (48-24) | 76-46 | Won 4 |
| » Starters: George Mogridge vs Stan Coveleski | First | -- |
| Wednesday, August 31 |
| » Defeated Tigers (59-68), 10-1 | Tiger Stadium (4-2) | 77-46 | Won 5 |
| » Starters: Allen Sothoron vs Hooks Dauss | First | -- |
| » Lost to Tigers (60-68), 7-3 | Tiger Stadium (4-3) | 77-47 | |
| » Starters: Duster Mails vs Dutch Leonard | First | -- |
| Thursday, September 1 |
| » Lost to Tigers (61-68), 7-6 | Tiger Stadium (4-4) | 77-48 | Lost 2 |
| » Starters: Stan Coveleski vs Red Oldham | Second | 1 out |
| Friday, September 2 |
| » Defeated Tigers (61-69), 12-1 | Tiger Stadium (5-4) | 78-48 | |
| » Starters: Jim Bagby vs Bert Cole | Second | 1 out |
| Saturday, September 3 |
| » Lost to Tigers (62-69), 10-7 | Tiger Stadium (5-5) | 78-49 | |
| » Starters: George Uhle vs Red Oldham | Second | 2 out |
| Sunday, September 4 |
| » Defeated Tigers (62-70), 9-5 | Tiger Stadium (6-5) | 79-49 | |
| » Starters: Allen Sothoron vs Hooks Dauss | Second | 1½ out |
| Monday, September 5 |
| » Defeated Browns (67-64), 10-5 | League Park II (49-24) | 80-49 | Won 2 |
| » Starters: Urban Shocker vs Duster Mails | Second | 1½ out |
| » Lost to Browns (68-64), 12-8 | League Park II (49-25) | 80-50 | |
| » Starters: Ray Kolp vs George Uhle | Second | 1½ out |
| Tuesday, September 6 |
| » Defeated Browns (68-65), 2-1 | League Park II (50-25) | 81-50 | |
| » Starters: Elam Vangilder vs Duster Mails | Second | 1½ out |
| Wednesday, September 7 |
| » Defeated Tigers (63-72), 5-4 | League Park II (51-25) | 82-50 | Won 2 |
| » Starters: Jim Middleton vs Jim Bagby | Second | 1 out |
| Thursday, September 8 |
| » Lost to Tigers (64-72), 15-1 | League Park II (51-26) | 82-51 | |
| » Starters: Hooks Dauss vs Allen Sothoron | Second | 1 out |
| Saturday, September 10 |
| » Lost to Browns (71-65), 2-0 | Sportsman's Park III (6-3) | 82-52 | Lost 2 |
| » Starters: Stan Coveleski vs Urban Shocker | Second | 2 out |
| » Defeated Browns (71-66), 10-2 | Sportsman's Park III (7-3) | 83-52 | |
| » Starters: Duster Mails vs Elam Vangilder | Second | 2 out |
| Sunday, September 11 |
| » Defeated Browns (71-67), 8-4 | Sportsman's Park III (8-3) | 84-52 | Won 2 |
| » Starters: Jim Bagby vs Ray Kolp | Second | 1½ out |
| Tuesday, September 13 |
| » Defeated Athletics (47-85), 11-5 | Shibe Park (5-3) | 85-52 | Won 3 |
| » Starters: Allen Sothoron vs Roy Moore | Second | ½ out |
| Wednesday, September 14 |
| » Defeated Athletics (47-86), 8-5 | Shibe Park (6-3) | 86-52 | Won 4 |
| » Starters: Stan Coveleski vs Rollie Naylor | Second | ½ out |
| Thursday, September 15 |
| » Defeated Athletics (47-87), 17-3 | Shibe Park (7-3) | 87-52 | Won 5 |
| » Starters: Duster Mails vs Arlas Taylor | Second | ½ out |
| » Defeated Athletics (47-88), 6-0 | Shibe Park (8-3) | 88-52 | Won 6 |
| » Starters: Ray Caldwell vs Eddie Rommel | Second | ½ out |
| Friday, September 16 |
| » Defeated Senators (69-71), 2-0 | Griffith Stadium (4-5) | 89-52 | Won 7 |
| » Starters: George Uhle vs Eric Erickson | First | -- |
| » Major-league debuts: Goose Goslin (Senators) |
| Saturday, September 17 |
| » Defeated Senators (69-72), 8-4 | Griffith Stadium (5-5) | 90-52 | Won 8 |
| » Starters: Allen Sothoron vs George Mogridge | First | -- |
| Sunday, September 18 |
| » Lost to Senators (70-72), 4-1 | Griffith Stadium (5-6) | 90-53 | |
| » Starters: Stan Coveleski vs Walter Johnson | Second | 1 out |
| Tuesday, September 20 |
| » Lost to Red Sox (70-70), 7-4 | Fenway Park (4-5) | 90-54 | Lost 2 |
| » Starters: George Uhle vs Herb Pennock | Second | ½ out |
| Wednesday, September 21 |
| » Defeated Red Sox (70-71), 5-1 | Fenway Park (5-5) | 91-54 | |
| » Starters: Ray Caldwell vs Sad Sam Jones | Second | 1 out |
| Thursday, September 22 |
| » Defeated Red Sox (70-72), 9-8 | Fenway Park (6-5) | 92-54 | Won 2 |
| » Starters: Allen Sothoron vs Allen Russell | Second | 1 out |
| Friday, September 23 |
| » Lost to Yankees (92-53), 4-2 | Polo Grounds V (3-5) | 92-55 | |
| » Starters: Stan Coveleski vs Waite Hoyt | Second | 1 out |
| Saturday, September 24 |
| » Defeated Yankees (92-54), 9-0 | Polo Grounds V (4-5) | 93-55 | |
| » Starters: George Uhle vs Harry Harper | Second | 1 out |
| Sunday, September 25 |
| » Lost to Yankees (93-54), 21-7 | Polo Grounds V (4-6) | 93-56 | |
| » Starters: Ray Caldwell vs Carl Mays | Second | 1 out |
| Monday, September 26 |
| » Lost to Yankees (94-54), 8-7 | Polo Grounds V (4-7) | 93-57 | Lost 2 |
| » Starters: Stan Coveleski vs Jack Quinn | Second | 2 out |
| Thursday, September 29 |
| » Lost to White Sox (60-91), 5-0 | Comiskey Park I (5-3) | 93-58 | Lost 3 |
| » Starters: Allen Sothoron vs Dickie Kerr | Second | 2½ out |
| Friday, September 30 |
| » Defeated White Sox (60-92), 3-2 | Comiskey Park I (6-3) | 94-58 | |
| » Starters: Stan Coveleski vs Red Faber | Second | 2 out |
| Saturday, October 1 |
| » Lost to White Sox (61-92), 8-5 | Comiskey Park I (6-4) | 94-59 | |
| » Starters: George Uhle vs John Russell | Second | 3½ out |
| Sunday, October 2 |
| » Lost to White Sox (62-92), 7-4 | Comiskey Park I (6-5) | 94-60 | Lost 2 |
| » Starters: Bernie Henderson vs Roy Wilkinson | Second | 4½ out |
Game information provided by Retrosheet (www.retrosheet.org) |