| Tuesday, January 6 |
| Future White Sox Early Wynn is born in Hartford, AL. |
| Wednesday, January 7 |
| Future White Sox Dixie Howell is born in Bowman, KY. |
| Friday, February 6 |
| Former White Sox Jack Lapp dies in Philadelphia, PA at the age of 36. |
| Friday, February 27 |
| Future White Sox Connie Ryan is born in New Orleans, LA. |
| Friday, April 2 |
| Former White Sox Matty McIntyre dies in Detroit, MI at the age of 40. |
| Wednesday, April 14 |
| » Defeated Tigers (0-1), 3-2 | Comiskey Park I (1-0) | 1-0 | |
| » Starters: Hooks Dauss vs Lefty Williams | First | -- |
| Saturday, April 17 |
| » Defeated Tigers (0-2), 4-0 | Comiskey Park I (2-0) | 2-0 | Won 2 |
| » Starters: Howard Ehmke vs Eddie Cicotte | First | -- |
| Wednesday, April 21 |
| » Defeated Browns (1-2), 7-4 | Comiskey Park I (3-0) | 3-0 | Won 3 |
| » Starters: Bert Gallia vs Lefty Williams | Second | 1 out |
| Thursday, April 22 |
| » Defeated Tigers (0-6), 8-2 | Tiger Stadium (1-0) | 4-0 | Won 4 |
| » Starters: Red Faber vs Dutch Leonard | First | -- |
| Saturday, April 24 |
| » Defeated Tigers (0-7), 7-1 | Tiger Stadium (2-0) | 5-0 | Won 5 |
| » Starters: Eddie Cicotte vs Hooks Dauss | First | -- |
| Sunday, April 25 |
| » Defeated Tigers (0-8), 2-1 | Tiger Stadium (3-0) | 6-0 | Won 6 |
| » Starters: Lefty Williams vs Howard Ehmke | First | -- |
| Monday, April 26 |
| » Major-league debuts: Huck Betts (Phillies) |
| Future White Sox Ron Northey is born in Mahanoy City, PA. |
| Tuesday, April 27 |
| » Lost to Indians (7-2), 3-2 | League Park II (0-1) | 6-1 | |
| » Starters: Red Faber vs Stan Coveleski | First | -- |
| Wednesday, April 28 |
| » Lost to Indians (8-2), 5-4 | League Park II (0-2) | 6-2 | Lost 2 |
| » Starters: Dickie Kerr vs Jim Bagby | Second | 1 out |
| Thursday, April 29 |
| » Defeated Indians (8-3), 6-1 | League Park II (1-2) | 7-2 | |
| » Starters: Lefty Williams vs Elmer Myers | Second | 1 out |
| Saturday, May 1 |
| » Defeated Browns (5-5), 8-5 | Sportsman's Park III (1-0) | 8-2 | Won 2 |
| » Starters: Red Faber vs Elam Vangilder | First | -- |
| Sunday, May 2 |
| » Defeated Browns (5-6), 7-3 | Sportsman's Park III (2-0) | 9-2 | Won 3 |
| » Starters: Roy Wilkinson vs Hod Leverette | First | -- |
| Monday, May 3 |
| » Defeated Browns (5-7), 7-1 | Sportsman's Park III (3-0) | 10-2 | Won 4 |
| » Starters: Lefty Williams vs Allen Sothoron | First | -- |
| Tuesday, May 4 |
| » Lost to Browns (6-7), 12-4 | Sportsman's Park III (3-1) | 10-3 | |
| » Starters: Dickie Kerr vs Carl Weilman | First | -- |
| Wednesday, May 5 |
| » Lost to Indians (11-5), 3-2 | Comiskey Park I (3-1) | 10-4 | Lost 2 |
| » Starters: Stan Coveleski vs Red Faber | First | -- |
| Thursday, May 6 |
| » Lost to Indians (12-5), 3-2 | Comiskey Park I (3-2) | 10-5 | Lost 3 |
| » Starters: Jim Bagby vs Roy Wilkinson | Third | 1½ out |
| Friday, May 7 |
| » Defeated Indians (12-6), 6-1 | Comiskey Park I (4-2) | 11-5 | |
| » Starters: Ray Caldwell vs Lefty Williams | First | -- |
| Saturday, May 8 |
| » Lost to Indians (13-6), 10-6 | Comiskey Park I (4-3) | 11-6 | |
| » Starters: Elmer Myers vs Red Faber | Second | 1 out |
| Sunday, May 9 |
| » Lost to Indians (14-6), 4-3 | Comiskey Park I (4-4) | 11-7 | Lost 2 |
| » Starters: Stan Coveleski vs Eddie Cicotte | Third | 2 out |
| Tuesday, May 11 |
| » Lost to Yankees (10-11), 6-5 | Polo Grounds V (0-1) | 11-8 | Lost 3 |
| » Starters: Roy Wilkinson vs Carl Mays | Third | 3 out |
| Wednesday, May 12 |
| » Lost to Yankees (11-11), 14-8 | Polo Grounds V (0-2) | 11-9 | Lost 4 |
| » Starters: Lefty Williams vs Hank Thormahlen | Third | 4 out |
| Saturday, May 15 |
| » Defeated Red Sox (14-8), 2-1 | Fenway Park (1-0) | 12-9 | |
| » Starters: Red Faber vs Herb Pennock | Third | 3 out |
| Sunday, May 16 |
| Future White Sox Dave Philley is born in Paris, TX. |
| Monday, May 17 |
| » Lost to Red Sox (15-8), 2-1 | Fenway Park (1-1) | 12-10 | |
| » Starters: Roy Wilkinson vs Sad Sam Jones | Third | 4 out |
| Tuesday, May 18 |
| » Defeated Red Sox (15-9), 4-3 | Fenway Park (2-1) | 13-10 | |
| » Starters: Lefty Williams vs Bullet Joe Bush | Third | 3 out |
| Wednesday, May 19 |
| » Lost to Red Sox (16-9), 3-2 | Fenway Park (2-2) | 13-11 | |
| » Starters: Eddie Cicotte vs Harry Harper | Third | 4 out |
| Thursday, May 20 |
| » Defeated Senators (13-14), 13-5 | Griffith Stadium (1-0) | 14-11 | |
| » Starters: Red Faber vs Harry Courtney | Third | 4 out |
| Friday, May 21 |
| » Defeated Senators (13-15), 11-9 | Griffith Stadium (2-0) | 15-11 | Won 2 |
| » Starters: Roy Wilkinson vs Al Schacht | Third | 4 out |
| Saturday, May 22 |
| » Defeated Senators (13-16), 10-6 | Griffith Stadium (3-0) | 16-11 | Won 3 |
| » Starters: Lefty Williams vs Tom Zachary | Third | 4 out |
| Sunday, May 23 |
| » Lost to Senators (14-16), 3-1 | Griffith Stadium (3-1) | 16-12 | |
| » Starters: Eddie Cicotte vs Eric Erickson | Third | 4 out |
| Monday, May 24 |
| » Defeated Athletics (10-19), 10-2 | Shibe Park (1-0) | 17-12 | |
| » Starters: Red Faber vs Rollie Naylor | Third | 3½ out |
| Tuesday, May 25 |
| » Lost to Athletics (11-19), 5-1 | Shibe Park (1-1) | 17-13 | |
| » Starters: Roy Wilkinson vs Roy Moore | Third | 4 out |
| Wednesday, May 26 |
| » Lost to Athletics (12-19), 10-2 | Shibe Park (1-2) | 17-14 | Lost 2 |
| » Starters: Lefty Williams vs Scott Perry | Third | 4½ out |
| Thursday, May 27 |
| » Defeated Athletics (12-20), 6-1 | Shibe Park (2-2) | 18-14 | |
| » Starters: Eddie Cicotte vs Pat Martin | Second | 3½ out |
| Friday, May 28 |
| » Lost to Indians (22-10), 13-6 | League Park II (1-3) | 18-15 | |
| » Starters: Red Faber vs Jim Bagby | Fourth | 4½ out |
| Saturday, May 29 |
| » Defeated Indians (22-11), 8-7 | League Park II (2-3) | 19-15 | |
| » Starters: Lefty Williams vs Elmer Myers | Fourth | 4½ out |
| » Lost to Indians (23-11), 8-1 | League Park II (2-4) | 19-16 | |
| » Starters: Roy Wilkinson vs Ray Caldwell | Fourth | 4½ out |
| Sunday, May 30 |
| » Lost to Indians (24-11), 8-6 | League Park II (2-5) | 19-17 | Lost 2 |
| » Starters: Eddie Cicotte vs Joe Boehling | Fifth | 5½ out |
| Monday, May 31 |
| » Lost to Browns (14-21), 2-0 | Sportsman's Park III (3-2) | 19-18 | Lost 3 |
| » Starters: Red Faber vs Urban Shocker | Fourth | 6½ out |
| » Defeated Browns (14-22), 5-3 | Sportsman's Park III (4-2) | 20-18 | |
| » Starters: Lefty Williams vs Elam Vangilder | Fourth | 6½ out |
| Wednesday, June 2 |
| » Defeated Browns (14-23), 7-3 | Sportsman's Park III (5-2) | 21-18 | Won 2 |
| » Starters: Eddie Cicotte vs Carl Weilman | Fourth | 6 out |
| Thursday, June 3 |
| » Defeated Browns (14-24), 6-4 | Sportsman's Park III (6-2) | 22-18 | Won 3 |
| » Starters: Roy Wilkinson vs Bill Burwell | Fourth | 5 out |
| Friday, June 4 |
| » Lost to Tigers (14-26), 6-3 | Comiskey Park I (4-5) | 22-19 | |
| » Starters: Hooks Dauss vs Red Faber | Fourth | 5 out |
| Saturday, June 5 |
| » Defeated Tigers (14-27), 4-1 | Comiskey Park I (5-5) | 23-19 | |
| » Starters: Howard Ehmke vs Lefty Williams | Fourth | 4 out |
| Sunday, June 6 |
| » Defeated Tigers (14-28), 7-6 | Comiskey Park I (6-5) | 24-19 | Won 2 |
| » Starters: Red Oldham vs Eddie Cicotte | Second | 3½ out |
| Monday, June 7 |
| » Defeated Tigers (14-29), 10-3 | Comiskey Park I (7-5) | 25-19 | Won 3 |
| » Starters: Dutch Leonard vs Red Faber | Third | 3 out |
| Tuesday, June 8 |
| » Lost to Red Sox (23-18), 4-1 | Comiskey Park I (7-6) | 25-20 | |
| » Starters: Sad Sam Jones vs Roy Wilkinson | Fourth | 4 out |
| Wednesday, June 9 |
| » Lost to Red Sox (24-18), 3-2 | Comiskey Park I (7-7) | 25-21 | Lost 2 |
| » Starters: Bullet Joe Bush vs Lefty Williams | Fifth | 5 out |
| Thursday, June 10 |
| » Lost to Red Sox (25-18), 8-1 | Comiskey Park I (7-8) | 25-22 | Lost 3 |
| » Starters: Harry Harper vs Eddie Cicotte | Fifth | 6 out |
| Friday, June 11 |
| » Defeated Red Sox (25-19), 5-4 | Comiskey Park I (8-8) | 26-22 | |
| » Starters: Herb Pennock vs Red Faber | Fourth | 6 out |
| Saturday, June 12 |
| » Defeated Senators (24-23), 9-8 | Comiskey Park I (9-8) | 27-22 | Won 2 |
| » Starters: Walter Johnson vs Roy Wilkinson | Fourth | 6 out |
| Sunday, June 13 |
| » Defeated Senators (24-24), 9-3 | Comiskey Park I (10-8) | 28-22 | Won 3 |
| » Starters: Harry Courtney vs Lefty Williams | Third | 5 out |
| Tuesday, June 15 |
| » Defeated Senators (24-25), 9-5 | Comiskey Park I (11-8) | 29-22 | Won 4 |
| » Starters: Tom Zachary vs Eddie Cicotte | Third | 5½ out |
| Wednesday, June 16 |
| » Lost to Yankees (35-20), 7-4 | Comiskey Park I (11-9) | 29-23 | |
| » Starters: Jack Quinn vs Red Faber | Third | 6 out |
| Future White Sox Eddie Malone is born in Chicago, IL. |
| Thursday, June 17 |
| » Lost to Yankees (36-20), 7-2 | Comiskey Park I (11-10) | 29-24 | Lost 2 |
| » Starters: Carl Mays vs Lefty Williams | Third | 6½ out |
| Friday, June 18 |
| » Lost to Yankees (37-20), 3-2 | Comiskey Park I (11-11) | 29-25 | Lost 3 |
| » Starters: Bob Shawkey vs Dickie Kerr | Third | 7½ out |
| Saturday, June 19 |
| » Defeated Yankees (37-21), 6-5 | Comiskey Park I (12-11) | 30-25 | |
| » Starters: George Mogridge vs Eddie Cicotte | Third | 6½ out |
| Sunday, June 20 |
| » Defeated Athletics (16-42), 7-5 | Comiskey Park I (13-11) | 31-25 | Won 2 |
| » Starters: Scott Perry vs Lefty Williams | Third | 5½ out |
| Tuesday, June 22 |
| » Defeated Athletics (16-43), 2-1 | Comiskey Park I (14-11) | 32-25 | Won 3 |
| » Starters: Slim Harriss vs Dickie Kerr | Third | 6 out |
| Wednesday, June 23 |
| » Defeated Athletics (16-44), 7-0 | Comiskey Park I (15-11) | 33-25 | Won 4 |
| » Starters: Roy Moore vs Eddie Cicotte | Third | 6 out |
| Friday, June 25 |
| » Defeated Indians (39-20), 6-3 | Comiskey Park I (16-11) | 34-25 | Won 5 |
| » Starters: Stan Coveleski vs Lefty Williams | Third | 5 out |
| Saturday, June 26 |
| » Defeated Indians (39-21), 12-7 | Comiskey Park I (17-11) | 35-25 | Won 6 |
| » Starters: Ray Caldwell vs Red Faber | Third | 4 out |
| Sunday, June 27 |
| » Lost to Indians (40-21), 4-1 | Comiskey Park I (17-12) | 35-26 | |
| » Starters: Jim Bagby vs Dickie Kerr | Third | 5 out |
| Monday, June 28 |
| » Defeated Tigers (21-41), 13-5 | Tiger Stadium (4-0) | 36-26 | |
| » Starters: Eddie Cicotte vs Doc Ayers | Third | 5 out |
| Tuesday, June 29 |
| » Defeated Tigers (21-42), 8-7 | Tiger Stadium (5-0) | 37-26 | Won 2 |
| » Starters: Lefty Williams vs Howard Ehmke | Third | 5½ out |
| Wednesday, June 30 |
| » Defeated Tigers (21-43), 14-0 | Tiger Stadium (6-0) | 38-26 | Won 3 |
| » Starters: Red Faber vs Dutch Leonard | Third | 4½ out |
| Thursday, July 1 |
| » Defeated Browns (31-35), 3-2 | Comiskey Park I (18-12) | 39-26 | Won 4 |
| » Starters: Elam Vangilder vs Eddie Cicotte | Third | 5 out |
| » Lost to Browns (32-35), 4-1 | Comiskey Park I (18-13) | 39-27 | |
| » Starters: Bill Bayne vs Dickie Kerr | Third | 5 out |
| Friday, July 2 |
| » Lost to Browns (33-35), 7-5 | Comiskey Park I (18-14) | 39-28 | Lost 2 |
| » Starters: Urban Shocker vs Lefty Williams | Third | 6 out |
| Saturday, July 3 |
| » Defeated Browns (33-36), 11-3 | Comiskey Park I (19-14) | 40-28 | |
| » Starters: Carl Weilman vs Red Faber | Third | 6½ out |
| Sunday, July 4 |
| » Defeated Browns (33-37), 6-3 | Comiskey Park I (20-14) | 41-28 | Won 2 |
| » Starters: Dixie Davis vs Eddie Cicotte | Third | 5½ out |
| Monday, July 5 |
| » Defeated Indians (46-23), 5-3 | Comiskey Park I (21-14) | 42-28 | Won 3 |
| » Starters: Ray Caldwell vs Lefty Williams | Third | 3½ out |
| » Defeated Indians (46-24), 6-5 | Comiskey Park I (22-14) | 43-28 | Won 4 |
| » Starters: Stan Coveleski vs Dickie Kerr | Third | 3½ out |
| Tuesday, July 6 |
| » Defeated Indians (46-25), 5-4 | Comiskey Park I (23-14) | 44-28 | Won 5 |
| » Starters: Jim Bagby vs Red Faber | Third | 3½ out |
| Thursday, July 8 |
| » Defeated Athletics (20-57), 8-5 | Shibe Park (3-2) | 45-28 | Won 6 |
| » Starters: Eddie Cicotte vs Roy Moore | Third | 3 out |
| Friday, July 9 |
| » Lost to Athletics (21-57), 5-4 | Shibe Park (3-3) | 45-29 | |
| » Starters: Lefty Williams vs Slim Harriss | Third | 4 out |
| Saturday, July 10 |
| » Defeated Athletics (21-58), 6-0 | Shibe Park (4-3) | 46-29 | |
| » Starters: Red Faber vs Rollie Naylor | Third | 3½ out |
| Monday, July 12 |
| » Defeated Athletics (21-59), 1-0 | Shibe Park (5-3) | 47-29 | Won 2 |
| » Starters: Dickie Kerr vs Scott Perry | Third | 3½ out |
| Tuesday, July 13 |
| » Defeated Senators (37-36), 5-3 | Griffith Stadium (4-1) | 48-29 | Won 3 |
| » Starters: Eddie Cicotte vs Tom Zachary | Third | 3½ out |
| Wednesday, July 14 |
| » Lost to Senators (38-36), 6-4 | Griffith Stadium (4-2) | 48-30 | |
| » Starters: Lefty Williams vs Jim Shaw | Third | 4½ out |
| Friday, July 16 |
| » Defeated Senators (38-37), 4-1 | Griffith Stadium (5-2) | 49-30 | |
| » Starters: Red Faber vs Walter Johnson | Third | 3½ out |
| » Defeated Senators (38-38), 8-5 | Griffith Stadium (6-2) | 50-30 | Won 2 |
| » Starters: Dickie Kerr vs Harry Courtney | Third | 3½ out |
| Saturday, July 17 |
| » Lost to Yankees (55-30), 20-5 | Polo Grounds V (0-3) | 50-31 | |
| » Starters: Eddie Cicotte vs Carl Mays | Third | 5 out |
| Sunday, July 18 |
| » Lost to Yankees (56-30), 8-4 | Polo Grounds V (0-4) | 50-32 | Lost 2 |
| » Starters: Lefty Williams vs Rip Collins | Third | 5½ out |
| Monday, July 19 |
| » Lost to Yankees (57-30), 8-2 | Polo Grounds V (0-5) | 50-33 | Lost 3 |
| » Starters: Roy Wilkinson vs Bob Shawkey | Third | 5½ out |
| » Defeated Yankees (57-31), 8-5 | Polo Grounds V (1-5) | 51-33 | |
| » Starters: Dickie Kerr vs Hank Thormahlen | Third | 5½ out |
| Tuesday, July 20 |
| » Defeated Yankees (57-32), 7-5 | Polo Grounds V (2-5) | 52-33 | Won 2 |
| » Starters: Red Faber vs Jack Quinn | Third | 6 out |
| » Lost to Yankees (58-32), 6-3 | Polo Grounds V (2-6) | 52-34 | |
| » Starters: Eddie Cicotte vs George Mogridge | Third | 6 out |
| Wednesday, July 21 |
| » Lost to Red Sox (39-44), 2-1 | Fenway Park (2-3) | 52-35 | Lost 2 |
| » Starters: Lefty Williams vs Sad Sam Jones | Third | 6 out |
| Thursday, July 22 |
| » Defeated Red Sox (39-45), 2-1 | Fenway Park (3-3) | 53-35 | |
| » Starters: Dickie Kerr vs Harry Harper | Third | 5 out |
| Friday, July 23 |
| » Defeated Red Sox (39-46), 8-7 | Fenway Park (4-3) | 54-35 | Won 2 |
| » Starters: Red Faber vs Herb Pennock | Third | 5 out |
| Saturday, July 24 |
| » Defeated Red Sox (39-47), 7-4 | Fenway Park (5-3) | 55-35 | Won 3 |
| » Starters: Eddie Cicotte vs Bullet Joe Bush | Third | 4 out |
| Sunday, July 25 |
| » Lost to Indians (60-31), 7-2 | League Park II (2-6) | 55-36 | |
| » Starters: Lefty Williams vs Stan Coveleski | Third | 5 out |
| Monday, July 26 |
| » Defeated Tigers (31-56), 6-4 | Tiger Stadium (7-0) | 56-36 | |
| » Starters: Dickie Kerr vs Hooks Dauss | Third | 4½ out |
| Tuesday, July 27 |
| » Defeated Tigers (31-57), 3-1 | Tiger Stadium (8-0) | 57-36 | Won 2 |
| » Starters: Red Faber vs Dutch Leonard | Third | 4 out |
| Wednesday, July 28 |
| » Defeated Athletics (27-67), 3-0 | Comiskey Park I (24-14) | 58-36 | Won 3 |
| » Starters: Slim Harriss vs Eddie Cicotte | Third | 4 out |
| Thursday, July 29 |
| » Defeated Athletics (27-68), 4-2 | Comiskey Park I (25-14) | 59-36 | Won 4 |
| » Starters: Eddie Rommel vs Lefty Williams | Third | 4½ out |
| » Lost to Athletics (28-68), 12-6 | Comiskey Park I (25-15) | 59-37 | |
| » Starters: Scott Perry vs Dickie Kerr | Third | 4½ out |
| Friday, July 30 |
| » Defeated Athletics (28-69), 6-5 | Comiskey Park I (26-15) | 60-37 | |
| » Starters: Rollie Naylor vs Red Faber | Third | 4½ out |
| Saturday, July 31 |
| » Lost to Athletics (29-69), 5-1 | Comiskey Park I (26-16) | 60-38 | |
| » Starters: Dave Keefe vs Roy Wilkinson | Third | 5½ out |
| Future White Sox Fred Bradley is born in Parsons, KS. |
| Sunday, August 1 |
| » Defeated Yankees (64-38), 3-0 | Comiskey Park I (27-16) | 61-38 | |
| » Starters: Bob Shawkey vs Eddie Cicotte | Third | 4½ out |
| Monday, August 2 |
| » Lost to Yankees (65-38), 7-0 | Comiskey Park I (27-17) | 61-39 | |
| » Starters: Jack Quinn vs Lefty Williams | Third | 5½ out |
| Tuesday, August 3 |
| » Defeated Yankees (65-39), 3-1 | Comiskey Park I (28-17) | 62-39 | |
| » Starters: Carl Mays vs Red Faber | Third | 5½ out |
| Wednesday, August 4 |
| » Defeated Yankees (65-40), 10-3 | Comiskey Park I (29-17) | 63-39 | Won 2 |
| » Starters: George Mogridge vs Dickie Kerr | Third | 4½ out |
| Future White Sox Bob Keegan is born in Rochester, NY. |
| Thursday, August 5 |
| » Lost to Red Sox (44-54), 4-2 | Comiskey Park I (29-18) | 63-40 | |
| » Starters: Sad Sam Jones vs Eddie Cicotte | Third | 5 out |
| Friday, August 6 |
| » Defeated Red Sox (44-55), 4-3 | Comiskey Park I (30-18) | 64-40 | |
| » Starters: Elmer Myers vs Lefty Williams | Third | 4 out |
| Saturday, August 7 |
| » Lost to Red Sox (45-55), 4-2 | Comiskey Park I (30-19) | 64-41 | |
| » Starters: Harry Harper vs Red Faber | Third | 5 out |
| Sunday, August 8 |
| » Defeated Red Sox (45-56), 2-0 | Comiskey Park I (31-19) | 65-41 | |
| » Starters: Herb Pennock vs Dickie Kerr | Third | 5 out |
| Monday, August 9 |
| » Defeated Senators (46-54), 3-2 | Comiskey Park I (32-19) | 66-41 | Won 2 |
| » Starters: Jim Shaw vs Eddie Cicotte | Second | 3½ out |
| » Defeated Senators (46-55), 5-4 | Comiskey Park I (33-19) | 67-41 | Won 3 |
| » Starters: Harry Courtney vs Lefty Williams | Second | 3½ out |
| Tuesday, August 10 |
| » Defeated Senators (46-56), 4-3 | Comiskey Park I (34-19) | 68-41 | Won 4 |
| » Starters: Jose Acosta vs Red Faber | Second | 3 out |
| Wednesday, August 11 |
| » Defeated Senators (46-57), 2-1 | Comiskey Park I (35-19) | 69-41 | Won 5 |
| » Starters: Eric Erickson vs Dickie Kerr | Second | 2 out |
| Thursday, August 12 |
| » Defeated Senators (46-58), 7-2 | Comiskey Park I (36-19) | 70-41 | Won 6 |
| » Starters: Harry Courtney vs Eddie Cicotte | Second | 2 out |
| Saturday, August 14 |
| » Defeated Tigers (40-66), 5-2 | Tiger Stadium (9-0) | 71-41 | Won 7 |
| » Starters: Dickie Kerr vs Red Oldham | Third | 2 out |
| » Lost to Tigers (41-66), 6-1 | Tiger Stadium (9-1) | 71-42 | |
| » Starters: Red Faber vs Howard Ehmke | Third | 2 out |
| Sunday, August 15 |
| » Defeated Tigers (41-67), 10-3 | Tiger Stadium (10-1) | 72-42 | |
| » Starters: Eddie Cicotte vs Dutch Leonard | Second | 2 out |
| Wednesday, August 18 |
| » Lost to Athletics (36-76), 1-0 | Shibe Park (5-4) | 72-43 | |
| » Starters: Lefty Williams vs Eddie Rommel | Second | 1½ out |
| Future White Sox Bob Kennedy is born in Chicago, IL. |
| Friday, August 20 |
| » Defeated Athletics (36-77), 7-4 | Shibe Park (6-4) | 73-43 | |
| » Starters: Red Faber vs Slim Harriss | Second | 2 out |
| » Athletics forfeited to White Sox. | Shibe Park (7-4) | 74-43 | Won 2 |
| » Starters: Dickie Kerr vs Scott Perry | Second | 2 out |
| Saturday, August 21 |
| » Defeated Senators (48-62), 5-2 | Griffith Stadium (7-2) | 75-43 | Won 3 |
| » Starters: Eddie Cicotte vs Tom Zachary | First | -- |
| Future White Sox Whitey Platt is born in West Palm Beach, FL. Future White Sox Gerry Staley is born in Brush Prairie, WA. |
| Sunday, August 22 |
| » Defeated Senators (48-63), 8-4 | Griffith Stadium (8-2) | 76-43 | Won 4 |
| » Starters: Lefty Williams vs Eric Erickson | First | -- |
| Tuesday, August 24 |
| » Lost to Senators (49-63), 8-5 | Griffith Stadium (8-3) | 76-44 | |
| » Starters: Red Faber vs Harry Courtney | First | -- |
| Thursday, August 26 |
| » Defeated Yankees (74-49), 16-4 | Polo Grounds V (3-6) | 77-44 | |
| » Starters: Dickie Kerr vs George Mogridge | First | -- |
| Friday, August 27 |
| » Lost to Yankees (75-49), 6-5 | Polo Grounds V (3-7) | 77-45 | |
| » Starters: Eddie Cicotte vs Carl Mays | First | -- |
| Saturday, August 28 |
| » Lost to Yankees (76-49), 3-0 | Polo Grounds V (3-8) | 77-46 | Lost 2 |
| » Starters: Red Faber vs Bob Shawkey | First | -- |
| Monday, August 30 |
| » Lost to Red Sox (58-64), 4-0 | Fenway Park (5-4) | 77-47 | Lost 3 |
| » Starters: Lefty Williams vs Sad Sam Jones | First | -- |
| Tuesday, August 31 |
| » Lost to Red Sox (59-64), 7-3 | Fenway Park (5-5) | 77-48 | Lost 4 |
| » Starters: Eddie Cicotte vs Bullet Joe Bush | First | -- |
| Wednesday, September 1 |
| » Lost to Red Sox (60-64), 6-2 | Fenway Park (5-6) | 77-49 | Lost 5 |
| » Starters: Dickie Kerr vs Herb Pennock | Second | ½ out |
| Friday, September 3 |
| » Lost to Browns (63-59), 2-1 | Comiskey Park I (36-20) | 77-50 | Lost 6 |
| » Starters: Dixie Davis vs Red Faber | Third | ½ out |
| Future White Sox Sandy Consuegra is born in Potrerillos, Cuba. |
| Saturday, September 4 |
| » Lost to Browns (64-59), 6-5 | Comiskey Park I (36-21) | 77-51 | Lost 7 |
| » Starters: Bill Bayne vs Eddie Cicotte | Third | 1 out |
| » Defeated Browns (64-60), 5-2 | Comiskey Park I (37-21) | 78-51 | |
| » Starters: Joe DeBerry vs Lefty Williams | Third | 1 out |
| Sunday, September 5 |
| » Defeated Browns (64-61), 4-1 | Comiskey Park I (38-21) | 79-51 | Won 2 |
| » Starters: Elam Vangilder vs Dickie Kerr | Second | 1 out |
| Future White Sox Gene Bearden is born in Lexa, AR. |
| Monday, September 6 |
| » Defeated Tigers (49-79), 6-2 | Comiskey Park I (39-21) | 80-51 | Won 3 |
| » Starters: Howard Ehmke vs Red Faber | Second | 1 out |
| » Defeated Tigers (49-80), 5-4 | Comiskey Park I (40-21) | 81-51 | Won 4 |
| » Starters: Doc Ayers vs Shovel Hodge | Second | 1 out |
| Tuesday, September 7 |
| » Lost to Tigers (50-80), 5-0 | Comiskey Park I (40-22) | 81-52 | |
| » Starters: Dutch Leonard vs Dickie Kerr | Third | 1½ out |
| Wednesday, September 8 |
| » Defeated Browns (64-64), 5-3 | Comiskey Park I (41-22) | 82-52 | |
| » Starters: Joe DeBerry vs Lefty Williams | Third | 2 out |
| Thursday, September 9 |
| » Defeated Red Sox (63-71), 6-5 | Comiskey Park I (42-22) | 83-52 | Won 2 |
| » Starters: Bullet Joe Bush vs Eddie Cicotte | Second | 2 out |
| Friday, September 10 |
| » Defeated Red Sox (63-72), 5-3 | Comiskey Park I (43-22) | 84-52 | Won 3 |
| » Starters: Herb Pennock vs Red Faber | Second | 2 out |
| Saturday, September 11 |
| » Lost to Red Sox (64-72), 9-7 | Comiskey Park I (43-23) | 84-53 | |
| » Starters: Sad Sam Jones vs Dickie Kerr | Third | 2 out |
| Sunday, September 12 |
| » Lost to Senators (60-71), 5-0 | Comiskey Park I (43-24) | 84-54 | Lost 2 |
| » Starters: Harry Courtney vs Lefty Williams | Third | 1½ out |
| Monday, September 13 |
| » Defeated Senators (60-72), 15-6 | Comiskey Park I (44-24) | 85-54 | |
| » Starters: Jim Shaw vs Red Faber | Third | 2 out |
| Tuesday, September 14 |
| » Lost to Senators (61-72), 7-0 | Comiskey Park I (44-25) | 85-55 | |
| » Starters: Jose Acosta vs Shovel Hodge | Third | 2½ out |
| Wednesday, September 15 |
| » Major-league debuts: Pie Traynor (Pirates) |
| Thursday, September 16 |
| » Defeated Yankees (88-54), 8-3 | Comiskey Park I (45-25) | 86-55 | |
| » Starters: Jack Quinn vs Dickie Kerr | Third | 1½ out |
| Friday, September 17 |
| » Defeated Yankees (88-55), 6-4 | Comiskey Park I (46-25) | 87-55 | Won 2 |
| » Starters: Hank Thormahlen vs Red Faber | Third | 1½ out |
| » Major-league debuts: Bibb Falk (White Sox) |
| Saturday, September 18 |
| » Defeated Yankees (88-56), 15-9 | Comiskey Park I (47-25) | 88-55 | Won 3 |
| » Starters: Bob Shawkey vs Eddie Cicotte | Second | 1½ out |
| Sunday, September 19 |
| » Defeated Athletics (46-96), 5-4 | Comiskey Park I (48-25) | 89-55 | Won 4 |
| » Starters: Eddie Rommel vs Lefty Williams | Second | 1½ out |
| Monday, September 20 |
| » Defeated Athletics (46-97), 13-6 | Comiskey Park I (49-25) | 90-55 | Won 5 |
| » Starters: Slim Harriss vs Red Faber | Second | 1½ out |
| Tuesday, September 21 |
| » Defeated Athletics (46-98), 9-2 | Comiskey Park I (50-25) | 91-55 | Won 6 |
| » Starters: Scott Perry vs Eddie Cicotte | Second | 1½ out |
| Wednesday, September 22 |
| » Major-league debuts: Clyde Barnhart (Pirates) |
| Thursday, September 23 |
| » Defeated Indians (91-53), 10-3 | League Park II (3-6) | 92-55 | Won 7 |
| » Starters: Dickie Kerr vs Jim Bagby | Second | 1½ out |
| Future White Sox Marino Pieretti is born in Lucca, Italy. |
| Friday, September 24 |
| » Lost to Indians (92-53), 2-0 | League Park II (3-7) | 92-56 | |
| » Starters: Red Faber vs Duster Mails | Second | 1½ out |
| Saturday, September 25 |
| » Defeated Indians (92-54), 5-1 | League Park II (4-7) | 93-56 | |
| » Starters: Lefty Williams vs Stan Coveleski | Second | 1½ out |
| Sunday, September 26 |
| » Defeated Tigers (59-90), 8-1 | Comiskey Park I (51-25) | 94-56 | Won 2 |
| » Starters: Howard Ehmke vs Eddie Cicotte | Second | 1½ out |
| Monday, September 27 |
| » Defeated Tigers (59-91), 2-0 | Comiskey Park I (52-25) | 95-56 | Won 3 |
| » Starters: Hooks Dauss vs Dickie Kerr | Second | 1½ out |
| Tuesday, September 28 |
| » Major-league debuts: Johnny Morrison (Pirates) |
| Friday, October 1 |
| » Lost to Browns (75-76), 8-6 | Sportsman's Park III (6-3) | 95-57 | |
| » Starters: Red Faber vs Dixie Davis | Second | 2 out |
| » Major-league debuts: Bubber Jonnard (White Sox) |
| Saturday, October 2 |
| » Defeated Browns (75-77), 10-7 | Sportsman's Park III (7-3) | 96-57 | |
| » Starters: Dickie Kerr vs Bill Bayne | Second | 2 out |
| Sunday, October 3 |
| » Lost to Browns (76-77), 16-7 | Sportsman's Park III (7-4) | 96-58 | |
| » Starters: Joe Kiefer vs Ray Richmond | Second | 2 out |
| Friday, October 8 |
| Future White Sox Catfish Metkovich is born in Angels Camp, CA. |
| Saturday, October 23 |
| Future White Sox Vern Stephens is born in McAlister, NM. |
| Tuesday, November 9 |
| Future White Sox Bill Mueller is born in Bay City, MI. |
| Tuesday, November 23 |
| Future White Sox Jake Jones is born in Epps, LA. |
| Friday, November 26 |
| Future White Sox Bud Sheely is born in Spokane, WA. |
| Monday, December 6 |
| Future White Sox Gus Niarhos is born in Birmingham, AL. |
| Thursday, December 9 |
| Former White Sox George Browne dies in Hyde Park, NY at the age of 45. |
| Wednesday, December 15 |
| Future White Sox Eddie Robinson is born in Paris, TX. |
Game information provided by Retrosheet (www.retrosheet.org) |
