| Thursday, January 15 |
| Future Tiger Steve Gromek is born in Hamtramck, MI. |
| Monday, February 2 |
| Future Tiger Zeb Eaton is born in Cooleemee, NC. |
| Wednesday, February 4 |
| Former Tiger Ed Siever dies in Detroit, MI at the age of 43. |
| Friday, April 2 |
| Former Tiger Matty McIntyre dies in Detroit, MI at the age of 40. |
| Wednesday, April 14 |
| » Lost to White Sox (1-0), 3-2 | Comiskey Park I (0-1) | 0-1 | |
| » Starters: Hooks Dauss vs Lefty Williams | Third | 1 out |
| Saturday, April 17 |
| » Lost to White Sox (2-0), 4-0 | Comiskey Park I (0-2) | 0-2 | Lost 2 |
| » Starters: Howard Ehmke vs Eddie Cicotte | Third | 2 out |
| Sunday, April 18 |
| » Lost to Indians (2-1), 11-4 | League Park II (0-1) | 0-3 | Lost 3 |
| » Starters: Doc Ayers vs Stan Coveleski | Fifth | 2½ out |
| Monday, April 19 |
| » Lost to Indians (3-1), 7-6 | League Park II (0-2) | 0-4 | Lost 4 |
| » Starters: Red Oldham vs Jim Bagby | Seventh | 4 out |
| Tuesday, April 20 |
| » Lost to Indians (4-1), 11-10 | League Park II (0-3) | 0-5 | Lost 5 |
| » Starters: Ernie Alten vs Ray Caldwell | Eighth | 5 out |
| » Major-league debuts: Sammy Hale (Tigers) |
| Thursday, April 22 |
| » Lost to White Sox (4-0), 8-2 | Tiger Stadium (0-1) | 0-6 | Lost 6 |
| » Starters: Red Faber vs Dutch Leonard | Seventh | 5 out |
| Saturday, April 24 |
| » Lost to White Sox (5-0), 7-1 | Tiger Stadium (0-2) | 0-7 | Lost 7 |
| » Starters: Eddie Cicotte vs Hooks Dauss | Seventh | 6 out |
| Sunday, April 25 |
| » Lost to White Sox (6-0), 2-1 | Tiger Stadium (0-3) | 0-8 | Lost 8 |
| » Starters: Lefty Williams vs Howard Ehmke | Eighth | 7 out |
| Monday, April 26 |
| » Lost to Browns (3-4), 4-1 | Sportsman's Park III (0-1) | 0-9 | Lost 9 |
| » Starters: Red Oldham vs Elam Vangilder | Seventh | 7½ out |
| Wednesday, April 28 |
| » Lost to Browns (4-4), 6-0 | Sportsman's Park III (0-2) | 0-10 | Lost 10 |
| » Starters: Dutch Leonard vs Urban Shocker | Sixth | 8 out |
| Thursday, April 29 |
| » Lost to Browns (5-4), 2-0 | Sportsman's Park III (0-3) | 0-11 | Lost 11 |
| » Starters: Hooks Dauss vs Allen Sothoron | Eighth | 9 out |
| Saturday, May 1 |
| » Lost to Indians (9-3), 9-3 | Tiger Stadium (0-4) | 0-12 | Lost 12 |
| » Starters: Stan Coveleski vs Howard Ehmke | Seventh | 9 out |
| Sunday, May 2 |
| » Lost to Indians (10-3), 5-2 | Tiger Stadium (0-5) | 0-13 | Lost 13 |
| » Starters: Jim Bagby vs Red Oldham | Seventh | 10 out |
| Monday, May 3 |
| » Defeated Indians (10-4), 5-1 | Tiger Stadium (1-5) | 1-13 | |
| » Starters: Guy Morton vs Dutch Leonard | Eighth | 10 out |
| Tuesday, May 4 |
| » Defeated Indians (10-5), 2-1 | Tiger Stadium (2-5) | 2-13 | Won 2 |
| » Starters: Elmer Myers vs Hooks Dauss | Seventh | 9 out |
| Wednesday, May 5 |
| » Lost to Browns (7-7), 12-4 | Tiger Stadium (2-6) | 2-14 | |
| » Starters: Roy Sanders vs Howard Ehmke | Eighth | 9 out |
| » Major-league debuts: Clyde Manion (Tigers) |
| Thursday, May 6 |
| » Defeated Browns (7-8), 6-4 | Tiger Stadium (3-6) | 3-14 | |
| » Starters: Elam Vangilder vs Red Oldham | Seventh | 9½ out |
| Friday, May 7 |
| » Lost to Browns (8-8), 10-4 | Tiger Stadium (3-7) | 3-15 | |
| » Starters: Allen Sothoron vs Dutch Leonard | Eighth | 9 out |
| Saturday, May 8 |
| » Defeated Browns (8-9), 5-4 | Tiger Stadium (4-7) | 4-15 | |
| » Starters: Hod Leverette vs Hooks Dauss | Seventh | 9 out |
| Sunday, May 9 |
| » Lost to Browns (9-9), 7-4 | Tiger Stadium (4-8) | 4-16 | |
| » Starters: Carl Weilman vs Howard Ehmke | Eighth | 10 out |
| Tuesday, May 11 |
| » Defeated Senators (10-11), 5-3 | Griffith Stadium (1-0) | 5-16 | |
| » Starters: Bernie Boland vs Al Schacht | Seventh | 10 out |
| Friday, May 14 |
| » Lost to Senators (11-11), 9-8 | Griffith Stadium (1-1) | 5-17 | |
| » Starters: John Glaiser vs Tom Zachary | Seventh | 11 out |
| Saturday, May 15 |
| » Lost to Athletics (8-13), 4-1 | Shibe Park (0-1) | 5-18 | Lost 2 |
| » Starters: Dutch Leonard vs Rollie Naylor | Seventh | 11 out |
| Monday, May 17 |
| » Defeated Athletics (8-14), 9-7 | Shibe Park (1-1) | 6-18 | |
| » Starters: Hooks Dauss vs Walt Kinney | Seventh | 11 out |
| Tuesday, May 18 |
| » Defeated Athletics (8-15), 8-2 | Shibe Park (2-1) | 7-18 | Won 2 |
| » Starters: Howard Ehmke vs Scott Perry | Eighth | 10 out |
| Wednesday, May 19 |
| » Lost to Athletics (9-15), 7-4 | Shibe Park (2-2) | 7-19 | |
| » Starters: Red Oldham vs Rollie Naylor | Seventh | 11 out |
| Thursday, May 20 |
| » Lost to Red Sox (17-9), 6-0 | Fenway Park (0-1) | 7-20 | Lost 2 |
| » Starters: Dutch Leonard vs Herb Pennock | Eighth | 12 out |
| » Major-league debuts: Larry Woodall (Tigers) |
| Friday, May 21 |
| » Lost to Red Sox (18-9), 8-3 | Fenway Park (0-2) | 7-21 | Lost 3 |
| » Starters: Hooks Dauss vs Allen Russell | Eighth | 13 out |
| Monday, May 24 |
| » Defeated Yankees (15-15), 3-1 | Polo Grounds V (1-0) | 8-21 | |
| » Starters: Howard Ehmke vs Carl Mays | Eighth | 12½ out |
| Tuesday, May 25 |
| » Lost to Yankees (16-15), 4-3 | Polo Grounds V (1-1) | 8-22 | |
| » Starters: Dutch Leonard vs Jack Quinn | Eighth | 13 out |
| Wednesday, May 26 |
| » Lost to Yankees (17-15), 4-1 | Polo Grounds V (1-2) | 8-23 | Lost 2 |
| » Starters: Hooks Dauss vs George Mogridge | Eighth | 13½ out |
| Friday, May 28 |
| » Defeated Browns (13-19), 3-1 | Sportsman's Park III (1-3) | 9-23 | |
| » Starters: Red Oldham vs Carl Weilman | Eighth | 13 out |
| Saturday, May 29 |
| » Defeated Browns (13-20), 5-3 | Sportsman's Park III (2-3) | 10-23 | Won 2 |
| » Starters: Howard Ehmke vs Dixie Davis | Eighth | 12½ out |
| Sunday, May 30 |
| » Defeated Browns (13-21), 6-2 | Sportsman's Park III (3-3) | 11-23 | Won 3 |
| » Starters: Dutch Leonard vs Allen Sothoron | Eighth | 12½ out |
| Monday, May 31 |
| » Lost to Indians (25-11), 9-5 | League Park II (0-4) | 11-24 | |
| » Starters: Hooks Dauss vs Elmer Myers | Eighth | 14½ out |
| » Lost to Indians (26-11), 7-3 | League Park II (0-5) | 11-25 | Lost 2 |
| » Starters: Doc Ayers vs Jim Bagby | Eighth | 14½ out |
| Tuesday, June 1 |
| » Defeated Indians (26-12), 11-10 | League Park II (1-5) | 12-25 | |
| » Starters: Red Oldham vs George Uhle | Eighth | 13½ out |
| Wednesday, June 2 |
| » Lost to Indians (27-12), 8-5 | League Park II (1-6) | 12-26 | |
| » Starters: Bernie Boland vs Ray Caldwell | Eighth | 14½ out |
| Thursday, June 3 |
| » Defeated Indians (27-13), 6-3 | League Park II (2-6) | 13-26 | |
| » Starters: Dutch Leonard vs Joe Boehling | Eighth | 13½ out |
| Friday, June 4 |
| » Defeated White Sox (22-19), 6-3 | Comiskey Park I (1-2) | 14-26 | Won 2 |
| » Starters: Hooks Dauss vs Red Faber | Eighth | 12½ out |
| Saturday, June 5 |
| » Lost to White Sox (23-19), 4-1 | Comiskey Park I (1-3) | 14-27 | |
| » Starters: Howard Ehmke vs Lefty Williams | Eighth | 12½ out |
| Sunday, June 6 |
| » Lost to White Sox (24-19), 7-6 | Comiskey Park I (1-4) | 14-28 | Lost 2 |
| » Starters: Red Oldham vs Eddie Cicotte | Seventh | 13 out |
| Monday, June 7 |
| » Lost to White Sox (25-19), 10-3 | Comiskey Park I (1-5) | 14-29 | Lost 3 |
| » Starters: Dutch Leonard vs Red Faber | Eighth | 13½ out |
| Tuesday, June 8 |
| » Lost to Yankees (30-17), 13-6 | Tiger Stadium (4-9) | 14-30 | Lost 4 |
| » Starters: George Mogridge vs Bernie Boland | Eighth | 14½ out |
| Wednesday, June 9 |
| » Lost to Yankees (31-17), 11-3 | Tiger Stadium (4-10) | 14-31 | Lost 5 |
| » Starters: Hank Thormahlen vs Howard Ehmke | Eighth | 15½ out |
| Thursday, June 10 |
| » Lost to Yankees (32-17), 7-5 | Tiger Stadium (4-11) | 14-32 | Lost 6 |
| » Starters: Carl Mays vs Frank Okrie | Eighth | 16½ out |
| Friday, June 11 |
| » Lost to Yankees (33-17), 5-0 | Tiger Stadium (4-12) | 14-33 | Lost 7 |
| » Starters: Rip Collins vs Dutch Leonard | Eighth | 17½ out |
| Saturday, June 12 |
| » Defeated Athletics (16-34), 4-3 | Tiger Stadium (5-12) | 15-33 | |
| » Starters: Rollie Naylor vs Hooks Dauss | Eighth | 17½ out |
| Sunday, June 13 |
| » Defeated Athletics (16-35), 4-3 | Tiger Stadium (6-12) | 16-33 | Won 2 |
| » Starters: Scott Perry vs Howard Ehmke | Seventh | 16½ out |
| Monday, June 14 |
| » Defeated Athletics (16-36), 5-0 | Tiger Stadium (7-12) | 17-33 | Won 3 |
| » Starters: Slim Harriss vs Doc Ayers | Seventh | 16½ out |
| Tuesday, June 15 |
| » Defeated Athletics (16-37), 3-2 | Tiger Stadium (8-12) | 18-33 | Won 4 |
| » Starters: Rollie Naylor vs Dutch Leonard | Seventh | 16½ out |
| Thursday, June 17 |
| » Lost to Red Sox (26-23), 2-1 | Tiger Stadium (8-13) | 18-34 | |
| » Starters: Bullet Joe Bush vs Hooks Dauss | Seventh | 17 out |
| Friday, June 18 |
| » Defeated Red Sox (26-24), 1-0 | Tiger Stadium (9-13) | 19-34 | |
| » Starters: Sad Sam Jones vs Doc Ayers | Seventh | 17 out |
| Saturday, June 19 |
| » Lost to Red Sox (27-24), 4-3 | Tiger Stadium (9-14) | 19-35 | |
| » Starters: Allen Russell vs Howard Ehmke | Seventh | 17 out |
| Sunday, June 20 |
| » Lost to Senators (26-26), 9-4 | Tiger Stadium (9-15) | 19-36 | Lost 2 |
| » Starters: Jim Shaw vs Dutch Leonard | Seventh | 17 out |
| Tuesday, June 22 |
| » Lost to Senators (27-26), 6-1 | Tiger Stadium (9-16) | 19-37 | Lost 3 |
| » Starters: Tom Zachary vs Hooks Dauss | Seventh | 18½ out |
| Future Tiger Walt Masterson is born in Philadelphia, PA. |
| Wednesday, June 23 |
| » Lost to Senators (28-26), 5-2 | Tiger Stadium (9-17) | 19-38 | Lost 4 |
| » Starters: Eric Erickson vs Doc Ayers | Seventh | 19½ out |
| Thursday, June 24 |
| » Defeated Browns (28-30), 5-0 | Sportsman's Park III (4-3) | 20-38 | |
| » Starters: Red Oldham vs Allen Sothoron | Seventh | 19 out |
| Friday, June 25 |
| » Lost to Browns (29-30), 10-6 | Sportsman's Park III (4-4) | 20-39 | |
| » Starters: Howard Ehmke vs Carl Weilman | Seventh | 19 out |
| Saturday, June 26 |
| » Defeated Browns (29-31), 5-2 | Sportsman's Park III (5-4) | 21-39 | |
| » Starters: Hooks Dauss vs Dixie Davis | Seventh | 18 out |
| Sunday, June 27 |
| » Lost to Browns (30-31), 3-1 | Sportsman's Park III (5-5) | 21-40 | |
| » Starters: Red Oldham vs Elam Vangilder | Seventh | 19 out |
| Monday, June 28 |
| » Lost to White Sox (36-26), 13-5 | Tiger Stadium (9-18) | 21-41 | Lost 2 |
| » Starters: Eddie Cicotte vs Doc Ayers | Seventh | 20 out |
| Tuesday, June 29 |
| » Lost to White Sox (37-26), 8-7 | Tiger Stadium (9-19) | 21-42 | Lost 3 |
| » Starters: Lefty Williams vs Howard Ehmke | Seventh | 21½ out |
| Wednesday, June 30 |
| » Lost to White Sox (38-26), 14-0 | Tiger Stadium (9-20) | 21-43 | Lost 4 |
| » Starters: Red Faber vs Dutch Leonard | Seventh | 21½ out |
| Friday, July 2 |
| » Lost to Indians (44-22), 10-3 | Tiger Stadium (9-21) | 21-44 | Lost 5 |
| » Starters: Stan Coveleski vs Hooks Dauss | Seventh | 23 out |
| Saturday, July 3 |
| » Lost to Indians (45-22), 6-3 | Tiger Stadium (9-22) | 21-45 | Lost 6 |
| » Starters: Jim Bagby vs Red Oldham | Seventh | 24½ out |
| Sunday, July 4 |
| » Lost to Indians (46-22), 11-3 | Tiger Stadium (9-23) | 21-46 | Lost 7 |
| » Starters: Guy Morton vs Dutch Leonard | Seventh | 24½ out |
| Monday, July 5 |
| » Lost to Browns (34-37), 5-4 | Tiger Stadium (9-24) | 21-47 | Lost 8 |
| » Starters: Allen Sothoron vs Howard Ehmke | Seventh | 23½ out |
| » Defeated Browns (34-38), 7-3 | Tiger Stadium (10-24) | 22-47 | |
| » Starters: Elam Vangilder vs Hooks Dauss | Seventh | 23½ out |
| Thursday, July 8 |
| » Defeated Yankees (49-27), 4-3 | Polo Grounds V (2-2) | 23-47 | Won 2 |
| » Starters: Doc Ayers vs Rip Collins | Seventh | 23½ out |
| Friday, July 9 |
| » Lost to Yankees (50-27), 9-3 | Polo Grounds V (2-3) | 23-48 | |
| » Starters: Red Oldham vs Jack Quinn | Seventh | 24½ out |
| Saturday, July 10 |
| » Lost to Yankees (51-27), 7-6 | Polo Grounds V (2-4) | 23-49 | Lost 2 |
| » Starters: Hooks Dauss vs Hank Thormahlen | Seventh | 25 out |
| Sunday, July 11 |
| » Lost to Yankees (52-27), 6-5 | Polo Grounds V (2-5) | 23-50 | Lost 3 |
| » Starters: Howard Ehmke vs Carl Mays | Seventh | 26 out |
| Tuesday, July 13 |
| » Defeated Red Sox (35-39), 10-4 | Fenway Park (1-2) | 24-50 | |
| » Starters: Dutch Leonard vs Herb Pennock | Seventh | 26 out |
| Wednesday, July 14 |
| » Lost to Red Sox (36-39), 6-5 | Fenway Park (1-3) | 24-51 | |
| » Starters: Doc Ayers vs Bullet Joe Bush | Seventh | 27½ out |
| » Lost to Red Sox (37-39), 4-0 | Fenway Park (1-4) | 24-52 | Lost 2 |
| » Starters: Red Oldham vs Herb Pennock | Seventh | 27½ out |
| Friday, July 16 |
| » Defeated Red Sox (37-40), 6-5 | Fenway Park (2-4) | 25-52 | |
| » Starters: Hooks Dauss vs Gary Fortune | Seventh | 27 out |
| Saturday, July 17 |
| » Defeated Senators (38-39), 10-1 | Griffith Stadium (2-1) | 26-52 | Won 2 |
| » Starters: Doc Ayers vs Jim Shaw | Seventh | 27 out |
| » Defeated Senators (38-40), 4-2 | Griffith Stadium (3-1) | 27-52 | Won 3 |
| » Starters: Howard Ehmke vs Tom Zachary | Seventh | 27 out |
| Sunday, July 18 |
| » Lost to Senators (39-40), 10-3 | Griffith Stadium (3-2) | 27-53 | |
| » Starters: Dutch Leonard vs Al Schacht | Seventh | 27½ out |
| Tuesday, July 20 |
| » Defeated Senators (39-41), 7-6 | Griffith Stadium (4-2) | 28-53 | |
| » Starters: Red Oldham vs Harry Courtney | Seventh | 27 out |
| » Defeated Senators (39-42), 2-1 | Griffith Stadium (5-2) | 29-53 | Won 2 |
| » Starters: Howard Ehmke vs Jim Shaw | Seventh | 27 out |
| Thursday, July 22 |
| » Lost to Athletics (26-64), 3-1 | Shibe Park (2-3) | 29-54 | |
| » Starters: Doc Ayers vs Slim Harriss | Seventh | 26½ out |
| Friday, July 23 |
| » Lost to Athletics (27-64), 4-1 | Shibe Park (2-4) | 29-55 | Lost 2 |
| » Starters: Dutch Leonard vs Eddie Rommel | Seventh | 27½ out |
| Saturday, July 24 |
| » Defeated Athletics (27-65), 5-0 | Shibe Park (3-4) | 30-55 | |
| » Starters: Howard Ehmke vs Scott Perry | Seventh | 26½ out |
| Sunday, July 25 |
| » Defeated Browns (42-47), 21-8 | Tiger Stadium (11-24) | 31-55 | Won 2 |
| » Starters: Urban Shocker vs Red Oldham | Seventh | 26½ out |
| Monday, July 26 |
| » Lost to White Sox (56-36), 6-4 | Tiger Stadium (11-25) | 31-56 | |
| » Starters: Dickie Kerr vs Hooks Dauss | Seventh | 27 out |
| Tuesday, July 27 |
| » Lost to White Sox (57-36), 3-1 | Tiger Stadium (11-26) | 31-57 | Lost 2 |
| » Starters: Red Faber vs Dutch Leonard | Seventh | 27½ out |
| Wednesday, July 28 |
| » Defeated Senators (43-44), 6-4 | Tiger Stadium (12-26) | 32-57 | |
| » Starters: Al Schacht vs Howard Ehmke | Seventh | 27½ out |
| » Major-league debuts: Jose Acosta (Senators) |
| Thursday, July 29 |
| » Lost to Senators (44-44), 2-1 | Tiger Stadium (12-27) | 32-58 | |
| » Starters: Jim Shaw vs Red Oldham | Seventh | 28 out |
| » Defeated Senators (44-45), 13-3 | Tiger Stadium (13-27) | 33-58 | |
| » Starters: Harry Courtney vs Hooks Dauss | Seventh | 28 out |
| Friday, July 30 |
| » Defeated Senators (44-46), 8-4 | Tiger Stadium (14-27) | 34-58 | Won 2 |
| » Starters: Tom Zachary vs Doc Ayers | Seventh | 28 out |
| Saturday, July 31 |
| » Defeated Senators (44-47), 3-2 | Tiger Stadium (15-27) | 35-58 | Won 3 |
| » Starters: Eric Erickson vs Dutch Leonard | Seventh | 28 out |
| Sunday, August 1 |
| » Lost to Red Sox (41-52), 4-2 | Tiger Stadium (15-28) | 35-59 | |
| » Starters: Waite Hoyt vs Howard Ehmke | Seventh | 28 out |
| Monday, August 2 |
| » Defeated Red Sox (41-53), 5-2 | Tiger Stadium (16-28) | 36-59 | |
| » Starters: Bullet Joe Bush vs Red Oldham | Seventh | 27½ out |
| » Defeated Red Sox (41-54), 2-1 | Tiger Stadium (17-28) | 37-59 | Won 2 |
| » Starters: Harry Harper vs Hooks Dauss | Seventh | 27½ out |
| Tuesday, August 3 |
| » Lost to Red Sox (42-54), 3-1 | Tiger Stadium (17-29) | 37-60 | |
| » Starters: Herb Pennock vs Doc Ayers | Seventh | 28½ out |
| Future Tiger Jim Hegan is born in Lynn, MA. |
| Wednesday, August 4 |
| » Lost to Red Sox (43-54), 5-1 | Tiger Stadium (17-30) | 37-61 | Lost 2 |
| » Starters: Bullet Joe Bush vs Dutch Leonard | Seventh | 28½ out |
| Thursday, August 5 |
| » Defeated Yankees (65-41), 7-1 | Tiger Stadium (18-30) | 38-61 | |
| » Starters: Bob Shawkey vs Howard Ehmke | Seventh | 28 out |
| Friday, August 6 |
| » Lost to Yankees (66-41), 11-7 | Tiger Stadium (18-31) | 38-62 | |
| » Starters: Jack Quinn vs Hooks Dauss | Seventh | 28 out |
| Saturday, August 7 |
| » Lost to Yankees (67-41), 7-3 | Tiger Stadium (18-32) | 38-63 | Lost 2 |
| » Starters: Carl Mays vs Doc Ayers | Seventh | 29 out |
| Sunday, August 8 |
| » Defeated Yankees (67-42), 1-0 | Tiger Stadium (19-32) | 39-63 | |
| » Starters: Rip Collins vs Howard Ehmke | Seventh | 29 out |
| Monday, August 9 |
| » Defeated Athletics (32-74), 5-2 | Tiger Stadium (20-32) | 40-63 | Won 2 |
| » Starters: Rollie Naylor vs Doc Ayers | Seventh | 28 out |
| Wednesday, August 11 |
| » Lost to Athletics (33-74), 13-4 | Tiger Stadium (20-33) | 40-64 | |
| » Starters: Eddie Rommel vs Hooks Dauss | Seventh | 28 out |
| Thursday, August 12 |
| » Lost to Athletics (34-74), 3-1 | Tiger Stadium (20-34) | 40-65 | Lost 2 |
| » Starters: Slim Harriss vs Doc Ayers | Seventh | 28 out |
| Saturday, August 14 |
| » Lost to White Sox (71-41), 5-2 | Tiger Stadium (20-35) | 40-66 | Lost 3 |
| » Starters: Dickie Kerr vs Red Oldham | Seventh | 27 out |
| » Defeated White Sox (71-42), 6-1 | Tiger Stadium (21-35) | 41-66 | |
| » Starters: Red Faber vs Howard Ehmke | Seventh | 27 out |
| Sunday, August 15 |
| » Lost to White Sox (72-42), 10-3 | Tiger Stadium (21-36) | 41-67 | |
| » Starters: Eddie Cicotte vs Dutch Leonard | Seventh | 28 out |
| Monday, August 16 |
| » Lost to Red Sox (50-58), 6-4 | Fenway Park (2-5) | 41-68 | Lost 2 |
| » Starters: Hooks Dauss vs Herb Pennock | Seventh | 29 out |
| Tuesday, August 17 |
| » Lost to Red Sox (51-58), 4-3 | Fenway Park (2-6) | 41-69 | Lost 3 |
| » Starters: Red Oldham vs Sad Sam Jones | Seventh | 29 out |
| » Defeated Red Sox (51-59), 3-1 | Fenway Park (3-6) | 42-69 | |
| » Starters: Howard Ehmke vs Harry Harper | Seventh | 29 out |
| Wednesday, August 18 |
| » Lost to Red Sox (52-59), 6-5 | Fenway Park (3-7) | 42-70 | |
| » Starters: Doc Ayers vs Elmer Myers | Seventh | 29 out |
| Future Tiger Bob Kennedy is born in Chicago, IL. |
| Thursday, August 19 |
| » Defeated Red Sox (52-60), 4-0 | Fenway Park (4-7) | 43-70 | |
| » Starters: Dutch Leonard vs Bullet Joe Bush | Seventh | 29 out |
| Saturday, August 21 |
| » Defeated Yankees (73-46), 10-3 | Polo Grounds V (3-5) | 44-70 | Won 2 |
| » Starters: Hooks Dauss vs Rip Collins | Seventh | 29 out |
| Future Tiger Gerry Staley is born in Brush Prairie, WA. |
| Sunday, August 22 |
| » Defeated Yankees (73-47), 11-9 | Polo Grounds V (4-5) | 45-70 | Won 3 |
| » Starters: Howard Ehmke vs Jack Quinn | Seventh | 29 out |
| Monday, August 23 |
| » Lost to Yankees (74-47), 10-0 | Polo Grounds V (4-6) | 45-71 | |
| » Starters: Dutch Leonard vs Carl Mays | Seventh | 29½ out |
| Tuesday, August 24 |
| » Defeated Yankees (74-48), 5-3 | Polo Grounds V (5-6) | 46-71 | |
| » Starters: Doc Ayers vs Bob Shawkey | Seventh | 28½ out |
| Thursday, August 26 |
| » Lost to Senators (50-63), 3-2 | Griffith Stadium (5-3) | 46-72 | |
| » Starters: Hooks Dauss vs Jim Shaw | Seventh | 29 out |
| » Defeated Senators (50-64), 5-4 | Griffith Stadium (6-3) | 47-72 | |
| » Starters: Red Oldham vs Tom Zachary | Seventh | 29 out |
| Friday, August 27 |
| » Lost to Senators (51-64), 3-1 | Griffith Stadium (6-4) | 47-73 | |
| » Starters: Howard Ehmke vs Jose Acosta | Seventh | 29 out |
| Monday, August 30 |
| » Defeated Athletics (39-83), 9-5 | Shibe Park (4-4) | 48-73 | |
| » Starters: Dutch Leonard vs Eddie Rommel | Seventh | 27½ out |
| Tuesday, August 31 |
| » Tied Athletics, 8-8 | Shibe Park (4-4) | 48-73 | |
| » Starters: Doc Ayers vs Slim Harriss | Seventh | 27 out |
| Wednesday, September 1 |
| » Lost to Athletics (40-83), 2-1 | Shibe Park (4-5) | 48-74 | |
| » Starters: Howard Ehmke vs Dave Keefe | Seventh | 28 out |
| » Lost to Athletics (41-83), 11-4 | Shibe Park (4-6) | 48-75 | Lost 2 |
| » Starters: Bill Morrisette vs Scott Perry | Seventh | 28 out |
| Thursday, September 2 |
| » Lost to Athletics (42-83), 2-0 | Shibe Park (4-7) | 48-76 | Lost 3 |
| » Starters: Red Oldham vs Slim Harriss | Seventh | 28½ out |
| Friday, September 3 |
| » Defeated Indians (77-49), 1-0 | League Park II (3-6) | 49-76 | |
| » Starters: Dutch Leonard vs Stan Coveleski | Seventh | 27½ out |
| Saturday, September 4 |
| » Lost to Indians (78-49), 12-3 | League Park II (3-7) | 49-77 | |
| » Starters: Doc Ayers vs Ray Caldwell | Seventh | 28½ out |
| Sunday, September 5 |
| » Lost to Indians (79-49), 4-3 | League Park II (3-8) | 49-78 | Lost 2 |
| » Starters: Hooks Dauss vs Jim Bagby | Seventh | 29½ out |
| Future Tiger Gene Bearden is born in Lexa, AR. |
| Monday, September 6 |
| » Lost to White Sox (80-51), 6-2 | Comiskey Park I (1-6) | 49-79 | Lost 3 |
| » Starters: Howard Ehmke vs Red Faber | Seventh | 31½ out |
| » Lost to White Sox (81-51), 5-4 | Comiskey Park I (1-7) | 49-80 | Lost 4 |
| » Starters: Doc Ayers vs Shovel Hodge | Seventh | 31½ out |
| Tuesday, September 7 |
| » Defeated White Sox (81-52), 5-0 | Comiskey Park I (2-7) | 50-80 | |
| » Starters: Dutch Leonard vs Dickie Kerr | Seventh | 31 out |
| Wednesday, September 8 |
| » Lost to Athletics (44-87), 5-4 | Tiger Stadium (21-37) | 50-81 | |
| » Starters: Rollie Naylor vs Hooks Dauss | Seventh | 31½ out |
| Friday, September 10 |
| » Defeated Athletics (44-88), 4-0 | Tiger Stadium (22-37) | 51-81 | |
| » Starters: Eddie Rommel vs Doc Ayers | Seventh | 30½ out |
| » Defeated Athletics (44-89), 5-2 | Tiger Stadium (23-37) | 52-81 | Won 2 |
| » Starters: Dave Keefe vs Bill Morrisette | Seventh | 30½ out |
| Saturday, September 11 |
| » Defeated Athletics (44-90), 5-2 | Tiger Stadium (24-37) | 53-81 | Won 3 |
| » Starters: Slim Harriss vs Mutt Wilson | Seventh | 29½ out |
| Sunday, September 12 |
| » Lost to Yankees (86-53), 13-6 | Tiger Stadium (24-38) | 53-82 | |
| » Starters: Carl Mays vs Hooks Dauss | Seventh | 31 out |
| Monday, September 13 |
| » Lost to Yankees (87-53), 4-2 | Tiger Stadium (24-39) | 53-83 | Lost 2 |
| » Starters: Carl Mays vs Howard Ehmke | Seventh | 31½ out |
| Tuesday, September 14 |
| » Lost to Yankees (88-53), 13-3 | Tiger Stadium (24-40) | 53-84 | Lost 3 |
| » Starters: Bob Shawkey vs Hooks Dauss | Seventh | 33 out |
| Wednesday, September 15 |
| » Major-league debuts: Pie Traynor (Pirates) |
| Thursday, September 16 |
| » Defeated Red Sox (66-75), 7-6 | Tiger Stadium (25-40) | 54-84 | |
| » Starters: Bullet Joe Bush vs Roy Crumpler | Seventh | 32 out |
| Friday, September 17 |
| » Defeated Red Sox (66-76), 14-13 | Tiger Stadium (26-40) | 55-84 | Won 2 |
| » Starters: Sad Sam Jones vs John Bogart | Seventh | 32 out |
| » Major-league debuts: Clarence Huber (Tigers) |
| Saturday, September 18 |
| » Lost to Red Sox (67-76), 7-4 | Tiger Stadium (26-41) | 55-85 | |
| » Starters: Elmer Myers vs Mutt Wilson | Seventh | 33 out |
| Sunday, September 19 |
| » Defeated Senators (61-76), 9-7 | Tiger Stadium (27-41) | 56-85 | |
| » Starters: Gus Bono vs Howard Ehmke | Seventh | 32½ out |
| » Defeated Senators (61-77), 3-2 | Tiger Stadium (28-41) | 57-85 | Won 2 |
| » Starters: Jim Shaw vs Hooks Dauss | Seventh | 32½ out |
| Monday, September 20 |
| » Lost to Senators (62-77), 9-3 | Tiger Stadium (28-42) | 57-86 | |
| » Starters: Tom Zachary vs Doc Ayers | Seventh | 33½ out |
| Tuesday, September 21 |
| » Defeated Senators (62-78), 12-11 | Tiger Stadium (29-42) | 58-86 | |
| » Starters: Eric Erickson vs Allen Conkwright | Seventh | 33½ out |
| Wednesday, September 22 |
| » Major-league debuts: Clyde Barnhart (Pirates) |
| Thursday, September 23 |
| » Lost to Browns (72-71), 8-4 | Tiger Stadium (29-43) | 58-87 | |
| » Starters: Dixie Davis vs Bill Morrisette | Seventh | 34 out |
| » Lost to Browns (73-71), 3-0 | Tiger Stadium (29-44) | 58-88 | Lost 2 |
| » Starters: Bill Bayne vs John Bogart | Seventh | 34 out |
| Friday, September 24 |
| » Defeated Browns (73-72), 16-8 | Tiger Stadium (30-44) | 59-88 | |
| » Starters: George Boehler vs Roy Crumpler | Seventh | 34 out |
| » Major-league debuts: Johnnie Heving (Browns) |
| Saturday, September 25 |
| » Lost to Browns (74-72), 7-5 | Sportsman's Park III (5-6) | 59-89 | |
| » Starters: Allen Conkwright vs Ray Richmond | Seventh | 34 out |
| Sunday, September 26 |
| » Lost to White Sox (94-56), 8-1 | Comiskey Park I (2-8) | 59-90 | Lost 2 |
| » Starters: Howard Ehmke vs Eddie Cicotte | Seventh | 35 out |
| Monday, September 27 |
| » Lost to White Sox (95-56), 2-0 | Comiskey Park I (2-9) | 59-91 | Lost 3 |
| » Starters: Hooks Dauss vs Dickie Kerr | Seventh | 36 out |
| Tuesday, September 28 |
| » Major-league debuts: Johnny Morrison (Pirates) |
| Friday, October 1 |
| » Defeated Indians (96-55), 5-4 | Tiger Stadium (31-44) | 60-91 | |
| » Starters: Duster Mails vs Howard Ehmke | Seventh | 37 out |
| » Lost to Indians (97-55), 10-3 | Tiger Stadium (31-45) | 60-92 | |
| » Starters: Ray Caldwell vs Doc Ayers | Seventh | 37 out |
| Saturday, October 2 |
| » Lost to Indians (98-55), 10-1 | Tiger Stadium (31-46) | 60-93 | Lost 2 |
| » Starters: Jim Bagby vs Red Oldham | Seventh | 38 out |
| Sunday, October 3 |
| » Defeated Indians (98-56), 6-5 | Tiger Stadium (32-46) | 61-93 | |
| » Starters: Guy Morton vs Allen Conkwright | Seventh | 37 out |
Game information provided by Retrosheet (www.retrosheet.org) |