| Wednesday, January 29 |
| Future White Sox Hank Edwards is born in Elmwood Place, OH. |
| Monday, March 3 |
| Future White Sox Steve Souchock is born in Yatesboro, PA. |
| Tuesday, March 25 |
| Future White Sox Bill Evans is born in Quanah, TX. |
| Wednesday, April 23 |
| » Defeated Browns (0-1), 13-4 | Sportsman's Park III (1-0) | 1-0 | |
| » Starters: Lefty Williams vs Dave Davenport | First | -- |
| Thursday, April 24 |
| » Defeated Browns (0-2), 5-2 | Sportsman's Park III (2-0) | 2-0 | Won 2 |
| » Starters: Eddie Cicotte vs Allen Sothoron | First | -- |
| Friday, April 25 |
| » Lost to Browns (1-2), 7-2 | Sportsman's Park III (2-1) | 2-1 | |
| » Starters: Dave Danforth vs Bert Gallia | Second | 1 out |
| » Major-league debuts: Dickey Kerr (White Sox) |
| Saturday, April 26 |
| » Defeated Browns (1-3), 9-4 | Sportsman's Park III (3-1) | 3-1 | |
| » Starters: Frank Shellenback vs Dave Davenport | Second | 1½ out |
| Sunday, April 27 |
| » Defeated Tigers (1-2), 6-4 | Tiger Stadium (1-0) | 4-1 | Won 2 |
| » Starters: Lefty Williams vs Hooks Dauss | Second | 1½ out |
| Tuesday, April 29 |
| » Defeated Tigers (1-3), 3-1 | Tiger Stadium (2-0) | 5-1 | Won 3 |
| » Starters: Eddie Cicotte vs Howard Ehmke | First | -- |
| Wednesday, April 30 |
| » Defeated Tigers (1-4), 9-7 | Tiger Stadium (3-0) | 6-1 | Won 4 |
| » Starters: Dickie Kerr vs Eric Erickson | First | -- |
| Thursday, May 1 |
| Future White Sox Al Zarilla is born in Los Angeles, CA. |
| Friday, May 2 |
| » Lost to Browns (2-5), 11-4 | Comiskey Park I (0-1) | 6-2 | |
| » Starters: Bert Gallia vs Lefty Williams | First | -- |
| Sunday, May 4 |
| » Defeated Browns (2-6), 4-2 | Comiskey Park I (1-1) | 7-2 | |
| » Starters: Allen Sothoron vs Eddie Cicotte | First | -- |
| Tuesday, May 6 |
| » Defeated Tigers (3-7), 3-1 | Comiskey Park I (2-1) | 8-2 | Won 2 |
| » Starters: Bernie Boland vs Lefty Williams | First | -- |
| Wednesday, May 7 |
| » Defeated Tigers (3-8), 9-3 | Comiskey Park I (3-1) | 9-2 | Won 3 |
| » Starters: Eric Erickson vs Red Faber | First | -- |
| Thursday, May 8 |
| » Defeated Indians (6-5), 4-1 | League Park II (1-0) | 10-2 | Won 4 |
| » Starters: Eddie Cicotte vs Stan Coveleski | First | -- |
| Saturday, May 10 |
| » Lost to Indians (7-5), 6-5 | League Park II (1-1) | 10-3 | |
| » Starters: Dickie Kerr vs Johnny Enzmann | First | -- |
| Sunday, May 11 |
| » Defeated Indians (7-6), 10-2 | League Park II (2-1) | 11-3 | |
| » Starters: Lefty Williams vs George Uhle | First | -- |
| Monday, May 12 |
| » Defeated Browns (3-10), 4-3 | Comiskey Park I (4-1) | 12-3 | Won 2 |
| » Starters: Bert Gallia vs Frank Shellenback | First | -- |
| Tuesday, May 13 |
| » Lost to Browns (4-10), 2-1 | Comiskey Park I (4-2) | 12-4 | |
| » Starters: Dave Davenport vs Charlie Robertson | First | -- |
| » Major-league debuts: Charlie Robertson (White Sox) |
| Wednesday, May 14 |
| » Defeated Red Sox (7-5), 1-0 | Comiskey Park I (5-2) | 13-4 | |
| » Starters: Carl Mays vs Eddie Cicotte | First | -- |
| Thursday, May 15 |
| » Lost to Red Sox (8-5), 6-5 | Comiskey Park I (5-3) | 13-5 | |
| » Starters: Bullet Joe Bush vs Lefty Williams | First | -- |
| Friday, May 16 |
| » Defeated Red Sox (8-6), 7-4 | Comiskey Park I (6-3) | 14-5 | |
| » Starters: Ray Caldwell vs Red Faber | First | -- |
| Saturday, May 17 |
| » Lost to Athletics (4-10), 1-0 | Comiskey Park I (6-4) | 14-6 | |
| » Starters: Tom Rogers vs Lefty Williams | First | -- |
| Sunday, May 18 |
| » Defeated Athletics (4-11), 1-0 | Comiskey Park I (7-4) | 15-6 | |
| » Starters: Scott Perry vs Eddie Cicotte | First | -- |
| Tuesday, May 20 |
| » Defeated Athletics (4-12), 2-1 | Comiskey Park I (8-4) | 16-6 | Won 2 |
| » Starters: Jing Johnson vs Red Faber | First | -- |
| Thursday, May 22 |
| » Defeated Yankees (10-6), 1-0 | Comiskey Park I (9-4) | 17-6 | Won 3 |
| » Starters: Jack Quinn vs Lefty Williams | First | -- |
| Friday, May 23 |
| » Defeated Yankees (10-7), 5-0 | Comiskey Park I (10-4) | 18-6 | Won 4 |
| » Starters: Bob Shawkey vs Eddie Cicotte | First | -- |
| Saturday, May 24 |
| » Lost to Yankees (11-7), 2-1 | Comiskey Park I (10-5) | 18-7 | |
| » Starters: Hank Thormahlen vs Red Faber | First | -- |
| Sunday, May 25 |
| » Defeated Senators (8-13), 6-5 | Comiskey Park I (11-5) | 19-7 | |
| » Starters: Jim Shaw vs Grover Lowdermilk | First | -- |
| Monday, May 26 |
| » Defeated Senators (8-14), 3-2 | Comiskey Park I (12-5) | 20-7 | Won 2 |
| » Starters: Harry Thompson vs Lefty Williams | First | -- |
| Tuesday, May 27 |
| » Defeated Senators (8-15), 4-3 | Comiskey Park I (13-5) | 21-7 | Won 3 |
| » Starters: Harry Harper vs Eddie Cicotte | First | -- |
| Friday, May 30 |
| » Defeated Indians (18-9), 4-1 | Comiskey Park I (14-5) | 22-7 | Won 4 |
| » Starters: Jim Bagby vs Red Faber | First | -- |
| » Defeated Indians (18-10), 3-2 | Comiskey Park I (15-5) | 23-7 | Won 5 |
| » Starters: Stan Coveleski vs Lefty Williams | First | -- |
| Saturday, May 31 |
| » Defeated Indians (18-11), 5-2 | Comiskey Park I (16-5) | 24-7 | Won 6 |
| » Starters: Tom Phillips vs Eddie Cicotte | First | -- |
| » Major-league debuts: Harvey McClellan (White Sox) |
| Sunday, June 1 |
| » Lost to Indians (19-11), 5-3 | Comiskey Park I (16-6) | 24-8 | |
| » Starters: Jim Bagby vs Dickie Kerr | First | -- |
| Monday, June 2 |
| » Lost to Tigers (15-16), 5-3 | Tiger Stadium (3-1) | 24-9 | Lost 2 |
| » Starters: Red Faber vs Howard Ehmke | First | -- |
| » Lost to Tigers (16-16), 2-1 | Tiger Stadium (3-2) | 24-10 | Lost 3 |
| » Starters: Lefty Williams vs Bernie Boland | First | -- |
| Tuesday, June 3 |
| » Lost to Tigers (17-16), 7-3 | Tiger Stadium (3-3) | 24-11 | Lost 4 |
| » Starters: Grover Lowdermilk vs Hooks Dauss | First | -- |
| Thursday, June 5 |
| » Defeated Yankees (19-12), 5-1 | Polo Grounds V (1-0) | 25-11 | |
| » Starters: Eddie Cicotte vs Ernie Shore | First | -- |
| Saturday, June 7 |
| » Lost to Yankees (20-12), 6-4 | Polo Grounds V (1-1) | 25-12 | |
| » Starters: Lefty Williams vs Jack Quinn | First | -- |
| Sunday, June 8 |
| » Lost to Yankees (21-12), 4-0 | Polo Grounds V (1-2) | 25-13 | Lost 2 |
| » Starters: Red Faber vs Bob Shawkey | First | -- |
| Tuesday, June 10 |
| » Defeated Red Sox (16-18), 5-3 | Fenway Park (1-0) | 26-13 | |
| » Starters: Eddie Cicotte vs Babe Ruth | First | -- |
| Wednesday, June 11 |
| » Defeated Red Sox (16-19), 3-0 | Fenway Park (2-0) | 27-13 | Won 2 |
| » Starters: Lefty Williams vs Carl Mays | First | -- |
| Thursday, June 12 |
| » Lost to Red Sox (17-19), 4-0 | Fenway Park (2-1) | 27-14 | |
| » Starters: Red Faber vs Herb Pennock | Second | 2½ out |
| Friday, June 13 |
| » Lost to Red Sox (18-19), 6-1 | Fenway Park (2-2) | 27-15 | Lost 2 |
| » Starters: Frank Shellenback vs Sad Sam Jones | Second | 2½ out |
| Saturday, June 14 |
| » Defeated Athletics (9-30), 6-3 | Shibe Park (1-0) | 28-15 | |
| » Starters: Eddie Cicotte vs Tom Rogers | Second | 2½ out |
| Monday, June 16 |
| » Defeated Athletics (9-31), 5-1 | Shibe Park (2-0) | 29-15 | Won 2 |
| » Starters: Lefty Williams vs Socks Seibold | First | -- |
| Tuesday, June 17 |
| » Defeated Athletics (9-32), 7-6 | Shibe Park (3-0) | 30-15 | Won 3 |
| » Starters: Red Faber vs Rollie Naylor | First | -- |
| Wednesday, June 18 |
| » Lost to Senators (17-27), 2-0 | Griffith Stadium (0-1) | 30-16 | |
| » Starters: Eddie Cicotte vs Jim Shaw | First | -- |
| Thursday, June 19 |
| » Defeated Senators (17-28), 5-4 | Griffith Stadium (1-1) | 31-16 | |
| » Starters: Grover Lowdermilk vs Charlie Whitehouse | First | -- |
| Friday, June 20 |
| » Defeated Senators (17-29), 5-2 | Griffith Stadium (2-1) | 32-16 | Won 2 |
| » Starters: Lefty Williams vs Harry Harper | First | -- |
| Saturday, June 21 |
| » Lost to Senators (18-29), 6-3 | Griffith Stadium (2-2) | 32-17 | |
| » Starters: Red Faber vs Walter Johnson | First | -- |
| Sunday, June 22 |
| » Lost to Tigers (23-26), 5-4 | Tiger Stadium (3-4) | 32-18 | Lost 2 |
| » Starters: Frank Shellenback vs Hooks Dauss | Second | 2½ out |
| Monday, June 23 |
| » Lost to Indians (32-18), 3-2 | Comiskey Park I (16-7) | 32-19 | Lost 3 |
| » Starters: Jim Bagby vs Eddie Cicotte | Third | 2½ out |
| Tuesday, June 24 |
| » Lost to Indians (33-18), 2-0 | Comiskey Park I (16-8) | 32-20 | Lost 4 |
| » Starters: Stan Coveleski vs Lefty Williams | Third | 2½ out |
| Wednesday, June 25 |
| » Defeated Indians (33-19), 7-1 | Comiskey Park I (17-8) | 33-20 | |
| » Starters: Guy Morton vs Grover Lowdermilk | Third | 2½ out |
| Thursday, June 26 |
| » Lost to Browns (25-26), 3-2 | Sportsman's Park III (3-2) | 33-21 | |
| » Starters: Dickie Kerr vs Allen Sothoron | Third | 3 out |
| Friday, June 27 |
| » Lost to Browns (26-26), 4-1 | Sportsman's Park III (3-3) | 33-22 | Lost 2 |
| » Starters: Eddie Cicotte vs Carl Weilman | Third | 3½ out |
| Saturday, June 28 |
| » Defeated Browns (26-27), 3-2 | Sportsman's Park III (4-3) | 34-22 | |
| » Starters: Lefty Williams vs Urban Shocker | Second | 3 out |
| Sunday, June 29 |
| » Lost to Browns (27-27), 5-3 | Sportsman's Park III (4-4) | 34-23 | |
| » Starters: Grover Lowdermilk vs Bert Gallia | Second | 3 out |
| Monday, June 30 |
| » Defeated Indians (33-24), 5-2 | League Park II (3-1) | 35-23 | |
| » Starters: Eddie Cicotte vs Jim Bagby | Second | 2½ out |
| Tuesday, July 1 |
| » Lost to Indians (34-24), 14-9 | League Park II (3-2) | 35-24 | |
| » Starters: Lefty Williams vs Hi Jasper | Second | 3½ out |
| Wednesday, July 2 |
| » Defeated Indians (34-25), 6-4 | League Park II (4-2) | 36-24 | |
| » Starters: Dickie Kerr vs Stan Coveleski | Second | 2½ out |
| Thursday, July 3 |
| » Defeated Indians (34-26), 17-1 | League Park II (5-2) | 37-24 | Won 2 |
| » Starters: Lefty Williams vs Guy Morton | Second | 2½ out |
| Friday, July 4 |
| » Defeated Tigers (31-29), 8-1 | Comiskey Park I (18-8) | 38-24 | Won 3 |
| » Starters: Bernie Boland vs Eddie Cicotte | Second | 2½ out |
| » Defeated Tigers (31-30), 2-1 | Comiskey Park I (19-8) | 39-24 | Won 4 |
| » Starters: Slim Love vs Dickie Kerr | Second | 2½ out |
| Saturday, July 5 |
| » Lost to Tigers (32-30), 6-3 | Comiskey Park I (19-9) | 39-25 | |
| » Starters: Hooks Dauss vs Red Faber | Second | 2 out |
| Sunday, July 6 |
| » Defeated Tigers (32-31), 4-1 | Comiskey Park I (20-9) | 40-25 | |
| » Starters: Dutch Leonard vs Lefty Williams | Second | 2 out |
| Monday, July 7 |
| » Defeated Tigers (32-32), 8-3 | Comiskey Park I (21-9) | 41-25 | Won 2 |
| » Starters: Howard Ehmke vs Eddie Cicotte | Second | 2 out |
| Wednesday, July 9 |
| » Defeated Athletics (17-46), 8-7 | Comiskey Park I (22-9) | 42-25 | Won 3 |
| » Starters: Tom Rogers vs Dickie Kerr | Second | 2½ out |
| » Defeated Athletics (17-47), 6-2 | Comiskey Park I (23-9) | 43-25 | Won 4 |
| » Starters: Jing Johnson vs Red Faber | Second | 2½ out |
| Thursday, July 10 |
| » Defeated Athletics (17-48), 9-2 | Comiskey Park I (24-9) | 44-25 | Won 5 |
| » Starters: Rollie Naylor vs Lefty Williams | First | -- |
| Friday, July 11 |
| » Defeated Athletics (17-49), 7-1 | Comiskey Park I (25-9) | 45-25 | Won 6 |
| » Starters: Scott Perry vs Eddie Cicotte | First | -- |
| Saturday, July 12 |
| » Lost to Red Sox (31-37), 12-4 | Comiskey Park I (25-10) | 45-26 | |
| » Starters: Herb Pennock vs Dickie Kerr | First | -- |
| Sunday, July 13 |
| » Defeated Red Sox (31-38), 14-9 | Comiskey Park I (26-10) | 46-26 | |
| » Starters: Carl Mays vs Red Faber | First | -- |
| Monday, July 14 |
| » Defeated Red Sox (31-39), 9-3 | Comiskey Park I (27-10) | 47-26 | Won 2 |
| » Starters: Sad Sam Jones vs Lefty Williams | First | -- |
| Tuesday, July 15 |
| » Defeated Red Sox (31-40), 3-1 | Comiskey Park I (28-10) | 48-26 | Won 3 |
| » Starters: Bill James vs Eddie Cicotte | First | -- |
| Wednesday, July 16 |
| » Lost to Senators (33-43), 11-1 | Comiskey Park I (28-11) | 48-27 | |
| » Starters: Eric Erickson vs Grover Lowdermilk | First | -- |
| Thursday, July 17 |
| » Lost to Senators (34-43), 9-4 | Comiskey Park I (28-12) | 48-28 | Lost 2 |
| » Starters: Jim Shaw vs Red Faber | First | -- |
| Friday, July 18 |
| » Defeated Senators (34-44), 3-0 | Comiskey Park I (29-12) | 49-28 | |
| » Starters: Harry Harper vs Lefty Williams | First | -- |
| » Major-league debuts: John Sullivan (White Sox) |
| Saturday, July 19 |
| » Defeated Senators (34-45), 6-5 | Comiskey Park I (30-12) | 50-28 | Won 2 |
| » Starters: Walter Johnson vs John Sullivan | First | -- |
| Sunday, July 20 |
| » Defeated Yankees (44-32), 2-1 | Comiskey Park I (31-12) | 51-28 | Won 3 |
| » Starters: Ernie Shore vs Eddie Cicotte | First | -- |
| Monday, July 21 |
| » Defeated Yankees (44-33), 7-6 | Comiskey Park I (32-12) | 52-28 | Won 4 |
| » Starters: Bob Shawkey vs Lefty Williams | First | -- |
| » Defeated Yankees (44-34), 5-4 | Comiskey Park I (33-12) | 53-28 | Won 5 |
| » Starters: Hank Thormahlen vs Red Faber | First | -- |
| Tuesday, July 22 |
| » Lost to Yankees (45-34), 6-1 | Comiskey Park I (33-13) | 53-29 | |
| » Starters: Jack Quinn vs Dickie Kerr | First | -- |
| Thursday, July 24 |
| » Defeated Browns (43-38), 1-0 | Comiskey Park I (34-13) | 54-29 | |
| » Starters: Allen Sothoron vs Eddie Cicotte | First | -- |
| Friday, July 25 |
| » Defeated Browns (43-39), 6-4 | Comiskey Park I (35-13) | 55-29 | Won 2 |
| » Starters: Dave Davenport vs Lefty Williams | First | -- |
| Saturday, July 26 |
| » Lost to Browns (44-39), 5-2 | Comiskey Park I (35-14) | 55-30 | |
| » Starters: Urban Shocker vs Red Faber | First | -- |
| Sunday, July 27 |
| » Lost to Browns (45-39), 11-5 | Comiskey Park I (35-15) | 55-31 | Lost 2 |
| » Starters: Carl Weilman vs Lefty Williams | First | -- |
| Tuesday, July 29 |
| » Lost to Yankees (47-37), 10-1 | Polo Grounds V (1-3) | 55-32 | Lost 3 |
| » Starters: Eddie Cicotte vs Hank Thormahlen | First | -- |
| Wednesday, July 30 |
| » Lost to Yankees (48-37), 6-5 | Polo Grounds V (1-4) | 55-33 | Lost 4 |
| » Starters: Lefty Williams vs Bob Shawkey | First | -- |
| » Defeated Yankees (48-38), 5-3 | Polo Grounds V (2-4) | 56-33 | |
| » Starters: Red Faber vs Jack Quinn | First | -- |
| Thursday, July 31 |
| » Defeated Yankees (48-39), 7-2 | Polo Grounds V (3-4) | 57-33 | Won 2 |
| » Starters: Dickie Kerr vs Ernie Shore | First | -- |
| Saturday, August 2 |
| » Lost to Red Sox (40-48), 5-3 | Fenway Park (2-3) | 57-34 | |
| » Starters: Eddie Cicotte vs Paul Musser | First | -- |
| » Defeated Red Sox (40-49), 10-1 | Fenway Park (3-3) | 58-34 | |
| » Starters: Lefty Williams vs Herb Pennock | First | -- |
| Monday, August 4 |
| » Lost to Red Sox (41-49), 2-1 | Fenway Park (3-4) | 58-35 | |
| » Starters: Red Faber vs Sad Sam Jones | First | -- |
| Thursday, August 7 |
| » Defeated Athletics (25-65), 2-1 | Shibe Park (4-0) | 59-35 | |
| » Starters: Eddie Cicotte vs Scott Perry | First | -- |
| » Lost to Athletics (26-65), 3-2 | Shibe Park (4-1) | 59-36 | |
| » Starters: Lefty Williams vs Rollie Naylor | First | -- |
| Friday, August 8 |
| » Lost to Athletics (27-65), 5-4 | Shibe Park (4-2) | 59-37 | Lost 2 |
| » Starters: Red Faber vs Walt Kinney | First | -- |
| » Defeated Athletics (27-66), 6-2 | Shibe Park (5-2) | 60-37 | |
| » Starters: Grover Lowdermilk vs Tom Rogers | First | -- |
| Saturday, August 9 |
| » Lost to Senators (40-58), 11-6 | Griffith Stadium (2-3) | 60-38 | |
| » Starters: Erskine Mayer vs Walter Johnson | First | -- |
| Sunday, August 10 |
| » Defeated Senators (40-59), 1-0 | Griffith Stadium (3-3) | 61-38 | |
| » Starters: Eddie Cicotte vs Jim Shaw | First | -- |
| Monday, August 11 |
| » Defeated Senators (40-60), 7-4 | Griffith Stadium (4-3) | 62-38 | Won 2 |
| » Starters: Lefty Williams vs Harry Harper | First | -- |
| Thursday, August 14 |
| » Lost to Red Sox (46-52), 15-6 | Comiskey Park I (35-16) | 62-39 | |
| » Starters: Allen Russell vs Eddie Cicotte | First | -- |
| Friday, August 15 |
| » Defeated Red Sox (46-53), 6-5 | Comiskey Park I (36-16) | 63-39 | |
| » Starters: Waite Hoyt vs Lefty Williams | First | -- |
| Saturday, August 16 |
| » Defeated Red Sox (46-54), 7-6 | Comiskey Park I (37-16) | 64-39 | Won 2 |
| » Starters: Sad Sam Jones vs Grover Lowdermilk | First | -- |
| Sunday, August 17 |
| » Defeated Athletics (28-72), 3-1 | Comiskey Park I (38-16) | 65-39 | Won 3 |
| » Starters: Rollie Naylor vs Grover Lowdermilk | First | -- |
| Monday, August 18 |
| » Defeated Athletics (28-73), 11-6 | Comiskey Park I (39-16) | 66-39 | Won 4 |
| » Starters: Win Noyes vs Dickie Kerr | First | -- |
| Tuesday, August 19 |
| » Defeated Athletics (28-74), 8-7 | Comiskey Park I (40-16) | 67-39 | Won 5 |
| » Starters: Jing Johnson vs Grover Lowdermilk | First | -- |
| Wednesday, August 20 |
| » Defeated Senators (42-64), 10-3 | Comiskey Park I (41-16) | 68-39 | Won 6 |
| » Starters: Eric Erickson vs Eddie Cicotte | First | -- |
| Future White Sox Earl Harrist is born in Dubach, LA. |
| Thursday, August 21 |
| » Defeated Senators (42-65), 11-4 | Comiskey Park I (42-16) | 69-39 | Won 7 |
| » Starters: Tom Zachary vs Lefty Williams | First | -- |
| Friday, August 22 |
| » Defeated Senators (42-66), 3-0 | Comiskey Park I (43-16) | 70-39 | Won 8 |
| » Starters: Jim Shaw vs Bill James | First | -- |
| Saturday, August 23 |
| » Defeated Yankees (57-50), 10-2 | Comiskey Park I (44-16) | 71-39 | Won 9 |
| » Starters: Bob Shawkey vs Eddie Cicotte | First | -- |
| Sunday, August 24 |
| » Defeated Yankees (57-51), 4-1 | Comiskey Park I (45-16) | 72-39 | Won 10 |
| » Starters: Jack Quinn vs Lefty Williams | First | -- |
| Monday, August 25 |
| » Lost to Yankees (58-51), 6-5 | Comiskey Park I (45-17) | 72-40 | |
| » Starters: Hank Thormahlen vs Bill James | First | -- |
| Tuesday, August 26 |
| » Defeated Browns (59-52), 4-3 | Sportsman's Park III (5-4) | 73-40 | |
| » Starters: Dickie Kerr vs Allen Sothoron | First | -- |
| Wednesday, August 27 |
| » Defeated Browns (59-53), 6-5 | Sportsman's Park III (6-4) | 74-40 | Won 2 |
| » Starters: Lefty Williams vs Bert Gallia | First | -- |
| Friday, August 29 |
| » Defeated Indians (66-47), 3-2 | League Park II (6-2) | 75-40 | Won 3 |
| » Starters: Eddie Cicotte vs Ray Caldwell | First | -- |
| Future White Sox Orval Grove is born in Mineral, KS. |
| Saturday, August 30 |
| » Lost to Indians (67-47), 4-0 | League Park II (6-3) | 75-41 | |
| » Starters: Bill James vs Elmer Myers | First | -- |
| Sunday, August 31 |
| » Lost to Indians (68-47), 6-1 | League Park II (6-4) | 75-42 | Lost 2 |
| » Starters: Lefty Williams vs Stan Coveleski | First | -- |
| Future White Sox Jack Wallaesa is born in Easton, PA. |
| Monday, September 1 |
| » Defeated Tigers (68-49), 6-0 | Tiger Stadium (4-4) | 76-42 | |
| » Starters: Lefty Williams vs Hooks Dauss | First | -- |
| » Defeated Tigers (68-50), 5-1 | Tiger Stadium (5-4) | 77-42 | Won 2 |
| » Starters: Eddie Cicotte vs Bernie Boland | First | -- |
| Tuesday, September 2 |
| » Lost to Tigers (69-50), 4-3 | Tiger Stadium (5-5) | 77-43 | |
| » Starters: Dickie Kerr vs Howard Ehmke | First | -- |
| Friday, September 5 |
| » Defeated Indians (70-50), 9-1 | Comiskey Park I (46-17) | 78-43 | |
| » Starters: Elmer Myers vs Eddie Cicotte | First | -- |
| Saturday, September 6 |
| » Lost to Indians (71-50), 11-2 | Comiskey Park I (46-18) | 78-44 | |
| » Starters: Jim Bagby vs Lefty Williams | First | -- |
| Sunday, September 7 |
| » Defeated Indians (71-51), 8-3 | Comiskey Park I (47-18) | 79-44 | |
| » Starters: Stan Coveleski vs Dickie Kerr | First | -- |
| Tuesday, September 9 |
| » Defeated Senators (47-78), 2-0 | Griffith Stadium (5-3) | 80-44 | Won 2 |
| » Starters: Bill James vs Walter Johnson | First | -- |
| Thursday, September 11 |
| » Lost to Senators (48-78), 4-3 | Griffith Stadium (5-4) | 80-45 | |
| » Starters: Dickie Kerr vs Jim Shaw | First | -- |
| » Defeated Senators (48-79), 5-0 | Griffith Stadium (6-4) | 81-45 | |
| » Starters: Lefty Williams vs Tom Zachary | First | -- |
| Friday, September 12 |
| » Defeated Athletics (34-92), 7-0 | Shibe Park (6-2) | 82-45 | Won 2 |
| » Starters: Roy Wilkinson vs Lefty York | First | -- |
| Saturday, September 13 |
| » Defeated Athletics (34-93), 8-2 | Shibe Park (7-2) | 83-45 | Won 3 |
| » Starters: Grover Lowdermilk vs Jimmy Zinn | First | -- |
| Monday, September 15 |
| » Defeated Athletics (34-94), 11-10 | Shibe Park (8-2) | 84-45 | Won 4 |
| » Starters: Red Faber vs Lefty York | First | -- |
| Wednesday, September 17 |
| » Defeated Yankees (70-57), 2-0 | Polo Grounds V (4-4) | 85-45 | Won 5 |
| » Starters: Dickie Kerr vs Jack Quinn | First | -- |
| » Defeated Yankees (70-58), 11-2 | Polo Grounds V (5-4) | 86-45 | Won 6 |
| » Starters: Bill James vs Hank Thormahlen | First | -- |
| » Major-league debuts: Curt Walker (Yankees) |
| Thursday, September 18 |
| » Lost to Yankees (71-58), 6-4 | Polo Grounds V (5-5) | 86-46 | |
| » Starters: Erskine Mayer vs Carl Mays | First | -- |
| Friday, September 19 |
| » Defeated Red Sox (63-67), 3-2 | Fenway Park (4-4) | 87-46 | |
| » Starters: Eddie Cicotte vs Waite Hoyt | First | -- |
| Saturday, September 20 |
| » Lost to Red Sox (64-67), 4-3 | Fenway Park (4-5) | 87-47 | |
| » Starters: Lefty Williams vs Babe Ruth | First | -- |
| » Lost to Red Sox (65-67), 5-4 | Fenway Park (4-6) | 87-48 | Lost 2 |
| » Starters: Dickie Kerr vs Herb Pennock | First | -- |
| Wednesday, September 24 |
| » Defeated Browns (65-71), 6-5 | Comiskey Park I (48-18) | 88-48 | |
| » Starters: Allen Sothoron vs Eddie Cicotte | First | -- |
| Thursday, September 25 |
| » Lost to Browns (66-71), 3-1 | Comiskey Park I (48-19) | 88-49 | |
| » Starters: Elam Vangilder vs Lefty Williams | First | -- |
| Friday, September 26 |
| » Lost to Tigers (78-60), 10-7 | Comiskey Park I (48-20) | 88-50 | Lost 2 |
| » Starters: Hooks Dauss vs John Sullivan | First | -- |
| Saturday, September 27 |
| » Lost to Tigers (79-60), 7-5 | Comiskey Park I (48-21) | 88-51 | Lost 3 |
| » Starters: Howard Ehmke vs Win Noyes | First | -- |
| Sunday, September 28 |
| » Lost to Tigers (80-60), 10-9 | Comiskey Park I (48-22) | 88-52 | Lost 4 |
| » Starters: Doc Ayers vs Eddie Cicotte | First | -- |
| Wednesday, October 8 |
| Future White Sox Bob Gillespie is born in Columbus, OH. |
| Wednesday, December 31 |
| Future White Sox Tommy Byrne is born in Baltimore, MD. |
Game information provided by Retrosheet (www.retrosheet.org) |
