| Monday, February 24 |
| Future Red Sox Del Wilber is born in Lincoln Park, MI. |
| Tuesday, March 25 |
| Future Red Sox Bill Evans is born in Quanah, TX. |
| Wednesday, April 2 |
| Future Red Sox Earl Johnson is born in Redmond, WA. |
| Wednesday, April 23 |
| » Defeated Yankees (0-1), 10-0 | Polo Grounds V (1-0) | 1-0 | |
| » Starters: Carl Mays vs George Mogridge | First | -- |
| Thursday, April 24 |
| » Major-league debuts: Earl Smith (Giants) |
| Saturday, April 26 |
| » Major-league debuts: Art Reinhart (Cardinals) |
| Sunday, April 27 |
| » Defeated Senators (1-2), 8-0 | Griffith Stadium (1-0) | 2-0 | Won 2 |
| » Starters: Sad Sam Jones vs Jim Shaw | First | -- |
| Monday, April 28 |
| » Defeated Senators (1-3), 6-5 | Griffith Stadium (2-0) | 3-0 | Won 3 |
| » Starters: Carl Mays vs Walter Johnson | First | -- |
| Tuesday, April 29 |
| » Lost to Senators (2-3), 4-2 | Griffith Stadium (2-1) | 3-1 | |
| » Starters: Herb Pennock vs Harry Harper | Second | 1 out |
| Wednesday, April 30 |
| » Defeated Senators (2-4), 6-1 | Griffith Stadium (3-1) | 4-1 | |
| » Starters: Ray Caldwell vs Harry Thompson | Second | 1 out |
| Thursday, May 1 |
| » Lost to Yankees (3-2), 7-3 | Fenway Park (0-1) | 4-2 | |
| » Starters: George Mogridge vs Carl Mays | Second | 1½ out |
| Future Red Sox Al Zarilla is born in Los Angeles, CA. |
| Friday, May 2 |
| » Lost to Yankees (4-2), 3-1 | Fenway Park (0-2) | 4-3 | Lost 2 |
| » Starters: Allen Russell vs Sad Sam Jones | Third | 1½ out |
| Saturday, May 3 |
| » Defeated Yankees (4-3), 3-2 | Fenway Park (1-2) | 5-3 | |
| » Starters: Bob Shawkey vs Babe Ruth | Second | 1 out |
| Monday, May 5 |
| » Lost to Yankees (5-3), 5-1 | Fenway Park (1-3) | 5-4 | |
| » Starters: Jack Quinn vs George Dumont | Fourth | 2 out |
| Tuesday, May 6 |
| » Defeated Senators (6-5), 2-0 | Fenway Park (2-3) | 6-4 | |
| » Starters: Harry Harper vs Ray Caldwell | Second | 2 out |
| Thursday, May 8 |
| » Defeated Senators (6-6), 3-0 | Fenway Park (3-3) | 7-4 | Won 2 |
| » Starters: Walter Johnson vs Sad Sam Jones | Second | 2½ out |
| Wednesday, May 14 |
| » Lost to White Sox (13-4), 1-0 | Comiskey Park I (0-1) | 7-5 | |
| » Starters: Carl Mays vs Eddie Cicotte | Fourth | 3½ out |
| Thursday, May 15 |
| » Defeated White Sox (13-5), 6-5 | Comiskey Park I (1-1) | 8-5 | |
| » Starters: Bullet Joe Bush vs Lefty Williams | Fourth | 2½ out |
| Friday, May 16 |
| » Lost to White Sox (14-5), 7-4 | Comiskey Park I (1-2) | 8-6 | |
| » Starters: Ray Caldwell vs Red Faber | Fourth | 3½ out |
| Saturday, May 17 |
| » Lost to Browns (7-10), 2-1 | Sportsman's Park III (0-1) | 8-7 | Lost 2 |
| » Starters: Sad Sam Jones vs Bert Gallia | Fourth | 3½ out |
| Sunday, May 18 |
| » Lost to Browns (8-10), 4-3 | Sportsman's Park III (0-2) | 8-8 | Lost 3 |
| » Starters: Carl Mays vs Carl Weilman | Fourth | 4½ out |
| Tuesday, May 20 |
| » Defeated Browns (8-11), 6-4 | Sportsman's Park III (1-2) | 9-8 | |
| » Starters: Babe Ruth vs Dave Davenport | Fourth | 4½ out |
| Future Red Sox Harry Taylor is born in East Glenn, IN. |
| Wednesday, May 21 |
| » Lost to Tigers (7-14), 6-5 | Tiger Stadium (0-1) | 9-9 | |
| » Starters: Ray Caldwell vs Rudy Kallio | Fourth | 5 out |
| Thursday, May 22 |
| » Lost to Tigers (8-14), 6-3 | Tiger Stadium (0-2) | 9-10 | Lost 2 |
| » Starters: Sad Sam Jones vs Slim Love | Fifth | 6 out |
| Saturday, May 24 |
| » Lost to Tigers (9-14), 5-3 | Tiger Stadium (0-3) | 9-11 | Lost 3 |
| » Starters: Carl Mays vs Howard Ehmke | Fifth | 6½ out |
| Sunday, May 25 |
| » Lost to Indians (16-8), 3-2 | League Park II (0-1) | 9-12 | Lost 4 |
| » Starters: Carl Mays vs Jim Bagby | Fifth | 7½ out |
| Monday, May 26 |
| » Lost to Indians (17-8), 12-7 | League Park II (0-2) | 9-13 | Lost 5 |
| » Starters: Babe Ruth vs Guy Morton | Fifth | 8½ out |
| Tuesday, May 27 |
| » Lost to Indians (18-8), 6-4 | League Park II (0-3) | 9-14 | Lost 6 |
| » Starters: Sad Sam Jones vs Tom Phillips | Sixth | 9½ out |
| Thursday, May 29 |
| » Defeated Athletics (5-18), 7-1 | Shibe Park (1-0) | 10-14 | |
| » Starters: Carl Mays vs Tom Rogers | Sixth | 9 out |
| Friday, May 30 |
| » Defeated Athletics (5-19), 10-6 | Shibe Park (2-0) | 11-14 | Won 2 |
| » Starters: Babe Ruth vs Bob Geary | Sixth | 10 out |
| » Lost to Athletics (6-19), 4-3 | Shibe Park (2-1) | 11-15 | |
| » Starters: Herb Pennock vs Scott Perry | Sixth | 10 out |
| Saturday, May 31 |
| » Defeated Athletics (6-20), 6-4 | Shibe Park (3-1) | 12-15 | |
| » Starters: Sad Sam Jones vs Jing Johnson | Sixth | 10 out |
| Monday, June 2 |
| » Lost to Senators (10-19), 4-0 | Griffith Stadium (3-2) | 12-16 | |
| » Starters: Carl Mays vs Jim Shaw | Sixth | 9 out |
| Tuesday, June 3 |
| » Defeated Senators (10-20), 4-3 | Griffith Stadium (4-2) | 13-16 | |
| » Starters: Ray Caldwell vs Harry Harper | Sixth | 8 out |
| Wednesday, June 4 |
| » Defeated Senators (10-21), 8-3 | Griffith Stadium (5-2) | 14-16 | Won 2 |
| » Starters: Bill James vs Dick Robertson | Sixth | 7½ out |
| Thursday, June 5 |
| » Defeated Tigers (17-17), 2-1 | Fenway Park (4-3) | 15-16 | Won 3 |
| » Starters: Dutch Leonard vs Babe Ruth | Sixth | 7½ out |
| Friday, June 6 |
| » Defeated Tigers (17-18), 3-1 | Fenway Park (5-3) | 16-16 | Won 4 |
| » Starters: Howard Ehmke vs Herb Pennock | Fourth | 7 out |
| Saturday, June 7 |
| » Lost to Tigers (18-18), 10-5 | Fenway Park (5-4) | 16-17 | |
| » Starters: Hooks Dauss vs Ray Caldwell | Sixth | 7 out |
| Sunday, June 8 |
| Future Red Sox Charley Schanz is born in Anacortes, WA. |
| Tuesday, June 10 |
| » Lost to White Sox (26-13), 5-3 | Fenway Park (5-5) | 16-18 | Lost 2 |
| » Starters: Eddie Cicotte vs Babe Ruth | Fifth | 7½ out |
| Wednesday, June 11 |
| » Lost to White Sox (27-13), 3-0 | Fenway Park (5-6) | 16-19 | Lost 3 |
| » Starters: Lefty Williams vs Carl Mays | Sixth | 8½ out |
| Thursday, June 12 |
| » Defeated White Sox (27-14), 4-0 | Fenway Park (6-6) | 17-19 | |
| » Starters: Red Faber vs Herb Pennock | Fifth | 7 out |
| Friday, June 13 |
| » Defeated White Sox (27-15), 6-1 | Fenway Park (7-6) | 18-19 | Won 2 |
| » Starters: Frank Shellenback vs Sad Sam Jones | Fifth | 6 out |
| Saturday, June 14 |
| » Lost to Indians (26-16), 3-2 | Fenway Park (7-7) | 18-20 | |
| » Starters: Jim Bagby vs Babe Ruth | Fifth | 7 out |
| Monday, June 16 |
| » Lost to Indians (27-16), 1-0 | Fenway Park (7-8) | 18-21 | Lost 2 |
| » Starters: Stan Coveleski vs Carl Mays | Sixth | 8½ out |
| Tuesday, June 17 |
| » Lost to Indians (28-16), 4-3 | Fenway Park (7-9) | 18-22 | Lost 3 |
| » Starters: Guy Morton vs Herb Pennock | Sixth | 10 out |
| » Lost to Indians (29-16), 3-2 | Fenway Park (7-10) | 18-23 | Lost 4 |
| » Starters: Tom Phillips vs Sad Sam Jones | Sixth | 10 out |
| Wednesday, June 18 |
| » Lost to Browns (23-22), 3-2 | Fenway Park (7-11) | 18-24 | Lost 5 |
| » Starters: Allen Sothoron vs Bill James | Fifth | 10 out |
| Thursday, June 19 |
| » Defeated Browns (23-23), 2-1 | Fenway Park (8-11) | 19-24 | |
| » Starters: Urban Shocker vs Carl Mays | Fifth | 10 out |
| Friday, June 20 |
| » Defeated Browns (23-24), 3-1 | Fenway Park (9-11) | 20-24 | Won 2 |
| » Starters: Bert Gallia vs Babe Ruth | Sixth | 10 out |
| Saturday, June 21 |
| » Tied Browns, 3-3 | Fenway Park (9-11) | 20-24 | |
| » Starters: Carl Weilman vs Herb Pennock | Sixth | 9½ out |
| Sunday, June 22 |
| » Lost to Yankees (29-16), 6-2 | Polo Grounds V (1-1) | 20-25 | |
| » Starters: Sad Sam Jones vs Ernie Shore | Sixth | 9 out |
| Monday, June 23 |
| » Lost to Senators (19-30), 12-3 | Fenway Park (9-12) | 20-26 | Lost 2 |
| » Starters: Harry Harper vs Ray Caldwell | Sixth | 10 out |
| Tuesday, June 24 |
| » Defeated Senators (19-31), 5-2 | Fenway Park (10-12) | 21-26 | |
| » Starters: Dick Robertson vs Ray Caldwell | Sixth | 10 out |
| Wednesday, June 25 |
| » Lost to Senators (20-31), 8-3 | Fenway Park (10-13) | 21-27 | |
| » Starters: Jim Shaw vs Babe Ruth | Sixth | 10½ out |
| » Defeated Senators (20-32), 1-0 | Fenway Park (11-13) | 22-27 | |
| » Starters: Walter Johnson vs Sad Sam Jones | Sixth | 10½ out |
| Thursday, June 26 |
| » Lost to Senators (21-32), 3-1 | Fenway Park (11-14) | 22-28 | |
| » Starters: Harry Harper vs Herb Pennock | Sixth | 11 out |
| Saturday, June 28 |
| » Defeated Yankees (32-17), 2-0 | Polo Grounds V (2-1) | 23-28 | |
| » Starters: Carl Mays vs Hank Thormahlen | Sixth | 11 out |
| » Lost to Yankees (33-17), 4-1 | Polo Grounds V (2-2) | 23-29 | |
| » Starters: Carl Mays vs Ernie Shore | Sixth | 11 out |
| Sunday, June 29 |
| » Defeated Yankees (33-18), 5-3 | Polo Grounds V (3-2) | 24-29 | |
| » Starters: Sad Sam Jones vs George Mogridge | Sixth | 10 out |
| Monday, June 30 |
| » Lost to Yankees (34-18), 7-4 | Polo Grounds V (3-3) | 24-30 | |
| » Starters: Bill James vs Bob Shawkey | Sixth | 12 out |
| » Lost to Yankees (35-18), 4-2 | Polo Grounds V (3-4) | 24-31 | Lost 2 |
| » Starters: Herb Pennock vs Pete Schneider | Sixth | 12 out |
| Tuesday, July 1 |
| » Lost to Athletics (15-39), 7-4 | Shibe Park (3-2) | 24-32 | Lost 3 |
| » Starters: Ray Caldwell vs Bill Grevell | Sixth | 13 out |
| Wednesday, July 2 |
| » Defeated Athletics (15-40), 4-2 | Shibe Park (4-2) | 25-32 | |
| » Starters: Ray Caldwell vs Jing Johnson | Sixth | 12 out |
| Thursday, July 3 |
| » Defeated Athletics (15-41), 8-2 | Shibe Park (5-2) | 26-32 | Won 2 |
| » Starters: Sad Sam Jones vs Rollie Naylor | Sixth | 11 out |
| Friday, July 4 |
| » Defeated Athletics (15-42), 9-2 | Fenway Park (12-14) | 27-32 | Won 3 |
| » Starters: Walt Kinney vs Herb Pennock | Sixth | 11 out |
| » Defeated Athletics (15-43), 9-6 | Fenway Park (13-14) | 28-32 | Won 4 |
| » Starters: Scott Perry vs Bullet Joe Bush | Sixth | 11 out |
| Saturday, July 5 |
| » Lost to Athletics (16-43), 5-3 | Fenway Park (13-15) | 28-33 | |
| » Starters: Tom Rogers vs George Dumont | Sixth | 12 out |
| » Lost to Athletics (17-43), 8-6 | Fenway Park (13-16) | 28-34 | Lost 2 |
| » Starters: Jing Johnson vs Bill James | Sixth | 12 out |
| Monday, July 7 |
| » Defeated Athletics (17-44), 2-0 | Fenway Park (14-16) | 29-34 | |
| » Starters: Rollie Naylor vs Sad Sam Jones | Sixth | 11 out |
| » Defeated Athletics (17-45), 5-4 | Fenway Park (15-16) | 30-34 | Won 2 |
| » Starters: Scott Perry vs Herb Pennock | Sixth | 11 out |
| Wednesday, July 9 |
| » Lost to Browns (33-32), 3-0 | Sportsman's Park III (1-3) | 30-35 | |
| » Starters: Carl Mays vs Allen Sothoron | Fifth | 11 out |
| Thursday, July 10 |
| » Lost to Browns (34-32), 5-1 | Sportsman's Park III (1-4) | 30-36 | Lost 2 |
| » Starters: Sad Sam Jones vs Carl Weilman | Sixth | 13 out |
| » Lost to Browns (35-32), 4-3 | Sportsman's Park III (1-5) | 30-37 | Lost 3 |
| » Starters: Ray Caldwell vs Urban Shocker | Sixth | 13 out |
| Saturday, July 12 |
| » Defeated White Sox (45-26), 12-4 | Comiskey Park I (2-2) | 31-37 | |
| » Starters: Herb Pennock vs Dickie Kerr | Sixth | 12½ out |
| Sunday, July 13 |
| » Lost to White Sox (46-26), 14-9 | Comiskey Park I (2-3) | 31-38 | |
| » Starters: Carl Mays vs Red Faber | Fifth | 13½ out |
| Monday, July 14 |
| » Lost to White Sox (47-26), 9-3 | Comiskey Park I (2-4) | 31-39 | Lost 2 |
| » Starters: Sad Sam Jones vs Lefty Williams | Fifth | 14½ out |
| Tuesday, July 15 |
| » Lost to White Sox (48-26), 3-1 | Comiskey Park I (2-5) | 31-40 | Lost 3 |
| » Starters: Bill James vs Eddie Cicotte | Sixth | 15½ out |
| Wednesday, July 16 |
| » Lost to Indians (43-33), 3-1 | League Park II (0-4) | 31-41 | Lost 4 |
| » Starters: Herb Pennock vs Elmer Myers | Seventh | 15½ out |
| Thursday, July 17 |
| » Lost to Indians (44-33), 4-0 | League Park II (0-5) | 31-42 | Lost 5 |
| » Starters: Babe Ruth vs Guy Morton | Seventh | 15½ out |
| Friday, July 18 |
| » Defeated Indians (44-34), 8-7 | League Park II (1-5) | 32-42 | |
| » Starters: Ray Caldwell vs Hi Jasper | Seventh | 15½ out |
| Saturday, July 19 |
| » Lost to Indians (45-34), 7-4 | League Park II (1-6) | 32-43 | |
| » Starters: Sad Sam Jones vs Stan Coveleski | Seventh | 16½ out |
| Sunday, July 20 |
| » Defeated Tigers (43-35), 8-0 | Tiger Stadium (1-3) | 33-43 | |
| » Starters: Herb Pennock vs Bernie Boland | Sixth | 16½ out |
| Monday, July 21 |
| » Lost to Tigers (44-35), 6-2 | Tiger Stadium (1-4) | 33-44 | |
| » Starters: Babe Ruth vs Howard Ehmke | Sixth | 18 out |
| Tuesday, July 22 |
| » Lost to Tigers (45-35), 2-1 | Tiger Stadium (1-5) | 33-45 | Lost 2 |
| » Starters: Paul Musser vs Dutch Leonard | Sixth | 18 out |
| Wednesday, July 23 |
| » Defeated Tigers (45-36), 8-1 | Tiger Stadium (2-5) | 34-45 | |
| » Starters: Sad Sam Jones vs Slim Love | Sixth | 17½ out |
| Thursday, July 24 |
| » Defeated Yankees (45-35), 4-3 | Fenway Park (16-16) | 35-45 | Won 2 |
| » Starters: Bob Shawkey vs Herb Pennock | Sixth | 17½ out |
| Friday, July 25 |
| » Defeated Yankees (45-36), 8-6 | Fenway Park (17-16) | 36-45 | Won 3 |
| » Starters: Allen Russell vs Babe Ruth | Sixth | 17½ out |
| Saturday, July 26 |
| » Lost to Yankees (46-36), 8-5 | Fenway Park (17-17) | 36-46 | |
| » Starters: Jack Quinn vs Paul Musser | Sixth | 17½ out |
| Monday, July 28 |
| » Defeated Yankees (46-37), 5-1 | Fenway Park (18-17) | 37-46 | |
| » Starters: Pete Schneider vs Herb Pennock | Sixth | 16½ out |
| Tuesday, July 29 |
| » Lost to Tigers (49-37), 10-8 | Fenway Park (18-18) | 37-47 | |
| » Starters: Dutch Leonard vs Paul Musser | Sixth | 16½ out |
| Wednesday, July 30 |
| » Lost to Tigers (50-37), 3-1 | Fenway Park (18-19) | 37-48 | Lost 2 |
| » Starters: Hooks Dauss vs Sad Sam Jones | Sixth | 16½ out |
| » Defeated Tigers (50-38), 3-2 | Fenway Park (19-19) | 38-48 | |
| » Starters: Howard Ehmke vs Bill James | Sixth | 16½ out |
| Thursday, July 31 |
| » Defeated Tigers (50-39), 2-1 | Fenway Park (20-19) | 39-48 | Won 2 |
| » Starters: Doc Ayers vs Waite Hoyt | Fifth | 16½ out |
| Saturday, August 2 |
| » Defeated White Sox (57-34), 5-3 | Fenway Park (21-19) | 40-48 | Won 3 |
| » Starters: Eddie Cicotte vs Paul Musser | Fourth | 16½ out |
| » Lost to White Sox (58-34), 10-1 | Fenway Park (21-20) | 40-49 | |
| » Starters: Lefty Williams vs Herb Pennock | Fourth | 16½ out |
| Monday, August 4 |
| » Defeated White Sox (58-35), 2-1 | Fenway Park (22-20) | 41-49 | |
| » Starters: Red Faber vs Sad Sam Jones | Sixth | 15½ out |
| Tuesday, August 5 |
| » Defeated Indians (52-41), 7-5 | Fenway Park (23-20) | 42-49 | Won 2 |
| » Starters: Jim Bagby vs Waite Hoyt | Fifth | 15 out |
| Wednesday, August 6 |
| Future Red Sox Leon Culberson is born in Halls, GA. |
| Thursday, August 7 |
| » Defeated Indians (52-42), 8-7 | Fenway Park (24-20) | 43-49 | Won 3 |
| » Starters: Elmer Myers vs Herb Pennock | Sixth | 14½ out |
| Friday, August 8 |
| » Lost to Indians (53-42), 5-4 | Fenway Park (24-21) | 43-50 | |
| » Starters: Stan Coveleski vs Sad Sam Jones | Sixth | 15 out |
| Saturday, August 9 |
| » Lost to Browns (51-43), 5-3 | Fenway Park (24-22) | 43-51 | Lost 2 |
| » Starters: Lefty Leifield vs Allen Russell | Sixth | 14½ out |
| » Defeated Browns (51-44), 4-3 | Fenway Park (25-22) | 44-51 | |
| » Starters: Ernie Koob vs Waite Hoyt | Sixth | 14½ out |
| Monday, August 11 |
| » Defeated Browns (51-45), 1-0 | Fenway Park (26-22) | 45-51 | Won 2 |
| » Starters: Allen Sothoron vs Herb Pennock | Sixth | 15 out |
| Tuesday, August 12 |
| » Lost to Browns (52-45), 10-3 | Fenway Park (26-23) | 45-52 | |
| » Starters: Urban Shocker vs Sad Sam Jones | Sixth | 15½ out |
| Thursday, August 14 |
| » Defeated White Sox (62-39), 15-6 | Comiskey Park I (3-5) | 46-52 | |
| » Starters: Allen Russell vs Eddie Cicotte | Sixth | 14½ out |
| Friday, August 15 |
| » Lost to White Sox (63-39), 6-5 | Comiskey Park I (3-6) | 46-53 | |
| » Starters: Waite Hoyt vs Lefty Williams | Fifth | 15½ out |
| Saturday, August 16 |
| » Lost to White Sox (64-39), 7-6 | Comiskey Park I (3-7) | 46-54 | Lost 2 |
| » Starters: Sad Sam Jones vs Grover Lowdermilk | Fifth | 16½ out |
| Sunday, August 17 |
| » Defeated Browns (54-47), 2-1 | Sportsman's Park III (2-5) | 47-54 | |
| » Starters: Babe Ruth vs Allen Sothoron | Sixth | 16 out |
| » Defeated Browns (54-48), 6-1 | Sportsman's Park III (3-5) | 48-54 | Won 2 |
| » Starters: Herb Pennock vs Urban Shocker | Sixth | 16 out |
| Future Red Sox Clem Hausmann is born in Houston, TX. |
| Monday, August 18 |
| » Lost to Browns (55-48), 4-3 | Sportsman's Park III (3-6) | 48-55 | |
| » Starters: Allen Russell vs Bert Gallia | Sixth | 17 out |
| Tuesday, August 19 |
| » Lost to Browns (56-48), 5-0 | Sportsman's Park III (3-7) | 48-56 | Lost 2 |
| » Starters: Waite Hoyt vs Lefty Leifield | Sixth | 18 out |
| Wednesday, August 20 |
| » Lost to Indians (60-45), 5-2 | League Park II (1-7) | 48-57 | Lost 3 |
| » Starters: Sad Sam Jones vs George Uhle | Sixth | 19 out |
| Thursday, August 21 |
| » Defeated Indians (60-46), 4-3 | League Park II (2-7) | 49-57 | |
| » Starters: Herb Pennock vs Hi Jasper | Sixth | 19 out |
| Friday, August 22 |
| » Lost to Indians (61-46), 10-7 | League Park II (2-8) | 49-58 | |
| » Starters: Herb Pennock vs Jim Bagby | Sixth | 20 out |
| Saturday, August 23 |
| » Lost to Tigers (65-43), 8-4 | Tiger Stadium (2-6) | 49-59 | Lost 2 |
| » Starters: Waite Hoyt vs Hooks Dauss | Sixth | 21 out |
| Sunday, August 24 |
| » Defeated Tigers (65-44), 8-7 | Tiger Stadium (3-6) | 50-59 | |
| » Starters: Sad Sam Jones vs Doc Ayers | Sixth | 21 out |
| Monday, August 25 |
| » Defeated Tigers (65-45), 5-4 | Tiger Stadium (4-6) | 51-59 | Won 2 |
| » Starters: Allen Russell vs Dutch Leonard | Sixth | 20 out |
| Wednesday, August 27 |
| » Lost to Athletics (29-80), 6-4 | Fenway Park (26-24) | 51-60 | |
| » Starters: Win Noyes vs Waite Hoyt | Sixth | 21½ out |
| Thursday, August 28 |
| » Lost to Athletics (30-80), 8-3 | Fenway Park (26-25) | 51-61 | Lost 2 |
| » Starters: Rollie Naylor vs Bill James | Sixth | 21½ out |
| » Defeated Athletics (30-81), 2-0 | Fenway Park (27-25) | 52-61 | |
| » Starters: Jing Johnson vs Herb Pennock | Sixth | 21½ out |
| Friday, August 29 |
| » Defeated Athletics (30-82), 7-1 | Fenway Park (28-25) | 53-61 | Won 2 |
| » Starters: Walt Kinney vs Allen Russell | Fifth | 21½ out |
| Sunday, August 31 |
| » Lost to Senators (44-72), 6-2 | Griffith Stadium (5-3) | 53-62 | |
| » Starters: Sad Sam Jones vs Tom Zachary | Sixth | 21 out |
| Monday, September 1 |
| » Defeated Senators (44-73), 2-1 | Fenway Park (29-25) | 54-62 | |
| » Starters: Harry Harper vs Babe Ruth | Sixth | 21 out |
| » Defeated Senators (44-74), 4-1 | Fenway Park (30-25) | 55-62 | Won 2 |
| » Starters: Jim Shaw vs Allen Russell | Sixth | 21 out |
| Friday, September 5 |
| » Defeated Athletics (32-88), 15-7 | Shibe Park (6-2) | 56-62 | Won 3 |
| » Starters: Sad Sam Jones vs Win Noyes | Sixth | 20½ out |
| » Major-league debuts: Charlie High (Athletics) |
| Saturday, September 6 |
| » Defeated Athletics (32-89), 11-3 | Shibe Park (7-2) | 57-62 | Won 4 |
| » Starters: Herb Pennock vs Jing Johnson | Sixth | 19 out |
| » Defeated Athletics (32-90), 5-3 | Shibe Park (8-2) | 58-62 | Won 5 |
| » Starters: Allen Russell vs Walt Kinney | Sixth | 19 out |
| Monday, September 8 |
| » Defeated Yankees (66-53), 3-1 | Polo Grounds V (4-4) | 59-62 | Won 6 |
| » Starters: Sad Sam Jones vs Hank Thormahlen | Sixth | 18½ out |
| » Defeated Yankees (66-54), 3-0 | Polo Grounds V (5-4) | 60-62 | Won 7 |
| » Starters: Waite Hoyt vs George Mogridge | Sixth | 18½ out |
| Thursday, September 11 |
| » Defeated Browns (64-61), 4-0 | Fenway Park (31-25) | 61-62 | Won 8 |
| » Starters: Lefty Leifield vs Herb Pennock | Sixth | 18 out |
| » Defeated Browns (64-62), 6-0 | Fenway Park (32-25) | 62-62 | Won 9 |
| » Starters: Rolla Mapel vs Allen Russell | Sixth | 18 out |
| Friday, September 12 |
| » Lost to Indians (74-52), 4-3 | Fenway Park (32-26) | 62-63 | |
| » Starters: Stan Coveleski vs Sad Sam Jones | Sixth | 19 out |
| Saturday, September 13 |
| » Lost to Indians (75-52), 4-3 | Fenway Park (32-27) | 62-64 | Lost 2 |
| » Starters: Elmer Myers vs Waite Hoyt | Sixth | 20 out |
| Wednesday, September 17 |
| » Lost to Tigers (74-56), 7-6 | Fenway Park (32-28) | 62-65 | Lost 3 |
| » Starters: Hooks Dauss vs Herb Pennock | Fifth | 21½ out |
| » Defeated Tigers (74-57), 2-1 | Fenway Park (33-28) | 63-65 | |
| » Starters: Dutch Leonard vs Allen Russell | Fifth | 21½ out |
| Thursday, September 18 |
| » Lost to Tigers (75-57), 8-2 | Fenway Park (33-29) | 63-66 | |
| » Starters: Howard Ehmke vs Sad Sam Jones | Fifth | 21½ out |
| Friday, September 19 |
| » Lost to White Sox (87-46), 3-2 | Fenway Park (33-30) | 63-67 | Lost 2 |
| » Starters: Eddie Cicotte vs Waite Hoyt | Fifth | 22½ out |
| Saturday, September 20 |
| » Defeated White Sox (87-47), 4-3 | Fenway Park (34-30) | 64-67 | |
| » Starters: Lefty Williams vs Babe Ruth | Fifth | 20½ out |
| » Defeated White Sox (87-48), 5-4 | Fenway Park (35-30) | 65-67 | Won 2 |
| » Starters: Dickie Kerr vs Herb Pennock | Fifth | 20½ out |
| Wednesday, September 24 |
| » Defeated Yankees (74-59), 4-0 | Polo Grounds V (6-4) | 66-67 | Won 3 |
| » Starters: Sad Sam Jones vs Jack Quinn | Fifth | 21 out |
| » Lost to Yankees (75-59), 2-1 | Polo Grounds V (6-5) | 66-68 | |
| » Starters: Waite Hoyt vs Bob Shawkey | Fifth | 21 out |
| Friday, September 26 |
| » Major-league debuts: Fred Hofmann (Yankees) |
| Saturday, September 27 |
| » Lost to Senators (54-84), 7-5 | Griffith Stadium (5-4) | 66-69 | Lost 2 |
| » Starters: Allen Russell vs Rip Jordan | Fifth | 20½ out |
| » Lost to Senators (55-84), 4-1 | Griffith Stadium (5-5) | 66-70 | Lost 3 |
| » Starters: Allen Russell vs Harry Courtney | Fifth | 20½ out |
| Future Red Sox Johnny Pesky is born in Portland, OR. |
| Sunday, September 28 |
| » Lost to Senators (56-84), 8-7 | Griffith Stadium (5-6) | 66-71 | Lost 4 |
| » Starters: Bob McGraw vs Al Schacht | Fifth | 20½ out |
| Wednesday, October 8 |
| Future Red Sox Bob Gillespie is born in Columbus, OH. |
| Thursday, December 11 |
| Future Red Sox Merl Combs is born in Los Angeles, CA. |
Game information provided by Retrosheet (www.retrosheet.org) |