| Sunday, March 31 |
| Future Tiger Marv Grissom is born in Los Molinos, CA. |
| Monday, April 15 |
| » Major-league debuts: Truck Hannah (Yankees) |
| Tuesday, April 16 |
| » Major-league debuts: Charlie Hollocher (Cubs) |
| Thursday, April 18 |
| » Lost to Indians (1-0), 6-2 | League Park II (0-1) | 0-1 | |
| » Starters: Bernie Boland vs Stan Coveleski | Sixth | 2 out |
| Monday, April 22 |
| » Defeated White Sox (1-2), 7-3 | Comiskey Park I (1-0) | 1-1 | |
| » Starters: Bill James vs Eddie Cicotte | Third | 2½ out |
| Wednesday, April 24 |
| » Defeated Indians (4-2), 5-2 | Tiger Stadium (1-0) | 2-1 | Won 2 |
| » Starters: Jim Bagby vs Eric Erickson | Third | 3 out |
| Thursday, April 25 |
| » Lost to Indians (5-2), 8-4 | Tiger Stadium (1-1) | 2-2 | |
| » Starters: Fritz Coumbe vs Happy Finneran | Third | 3 out |
| » Major-league debuts: Rudy Kallio (Tigers) |
| Saturday, April 27 |
| » Lost to Indians (6-2), 3-2 | Tiger Stadium (1-2) | 2-3 | Lost 2 |
| » Starters: Stan Coveleski vs Bill James | Fifth | 4½ out |
| Monday, April 29 |
| » Lost to Browns (3-6), 12-3 | Sportsman's Park III (0-1) | 2-4 | Lost 3 |
| » Starters: Willie Mitchell vs Dave Davenport | Sixth | 5 out |
| Wednesday, May 1 |
| » Lost to Browns (4-6), 3-2 | Sportsman's Park III (0-2) | 2-5 | Lost 4 |
| » Starters: Eric Erickson vs Bert Gallia | Seventh | 5½ out |
| Thursday, May 2 |
| » Defeated White Sox (5-4), 9-6 | Tiger Stadium (2-2) | 3-5 | |
| » Starters: Red Faber vs Bill James | Sixth | 5½ out |
| Friday, May 3 |
| » Lost to White Sox (6-4), 19-3 | Tiger Stadium (2-3) | 3-6 | |
| » Starters: Lefty Williams vs Bill James | Seventh | 5½ out |
| Saturday, May 4 |
| » Defeated White Sox (6-5), 2-1 | Tiger Stadium (3-3) | 4-6 | |
| » Starters: Eddie Cicotte vs Bernie Boland | Sixth | 4½ out |
| Sunday, May 5 |
| » Defeated White Sox (6-6), 3-2 | Tiger Stadium (4-3) | 5-6 | Won 2 |
| » Starters: Dave Danforth vs Hooks Dauss | Fifth | 4 out |
| Monday, May 6 |
| » Defeated Browns (6-9), 9-3 | Tiger Stadium (5-3) | 6-6 | Won 3 |
| » Starters: Dave Davenport vs Eric Erickson | Fifth | 3 out |
| Tuesday, May 7 |
| » Lost to Browns (7-9), 5-3 | Tiger Stadium (5-4) | 6-7 | |
| » Starters: Bert Gallia vs Rudy Kallio | Fifth | 3 out |
| Wednesday, May 8 |
| » Lost to Browns (8-9), 8-1 | Tiger Stadium (5-5) | 6-8 | Lost 2 |
| » Starters: Allen Sothoron vs Bill James | Seventh | 3 out |
| Thursday, May 9 |
| » Lost to Indians (11-8), 6-3 | League Park II (0-2) | 6-9 | Lost 3 |
| » Starters: Bernie Boland vs Guy Morton | Seventh | 3 out |
| Friday, May 10 |
| » Defeated Yankees (11-10), 5-3 | Polo Grounds V (1-0) | 7-9 | |
| » Starters: Hooks Dauss vs George Mogridge | Seventh | 3 out |
| Saturday, May 11 |
| » Lost to Yankees (12-10), 6-5 | Polo Grounds V (1-1) | 7-10 | |
| » Starters: Bill James vs Slim Love | Seventh | 3 out |
| Monday, May 13 |
| » Lost to Yankees (13-10), 3-2 | Polo Grounds V (1-2) | 7-11 | Lost 2 |
| » Starters: Eric Erickson vs Allen Russell | Eighth | 4 out |
| Wednesday, May 15 |
| » Lost to Red Sox (15-10), 5-4 | Fenway Park (0-1) | 7-12 | Lost 3 |
| » Starters: Hooks Dauss vs Babe Ruth | Seventh | 5 out |
| Thursday, May 16 |
| » Lost to Red Sox (16-10), 7-2 | Fenway Park (0-2) | 7-13 | Lost 4 |
| » Starters: Bill James vs Carl Mays | Seventh | 6 out |
| Friday, May 17 |
| » Lost to Red Sox (17-10), 11-8 | Fenway Park (0-3) | 7-14 | Lost 5 |
| » Starters: Happy Finneran vs Dutch Leonard | Eighth | 7 out |
| Saturday, May 18 |
| » Lost to Red Sox (18-10), 3-1 | Fenway Park (0-4) | 7-15 | Lost 6 |
| » Starters: Eric Erickson vs Bullet Joe Bush | Seventh | 8 out |
| Future Tiger Rufe Gentry is born in Daisy Station, NC. |
| Monday, May 20 |
| » Lost to Athletics (12-15), 5-4 | Shibe Park (0-1) | 7-16 | Lost 7 |
| » Starters: Hooks Dauss vs Elmer Myers | Eighth | 9 out |
| Wednesday, May 22 |
| » Defeated Athletics (12-16), 3-1 | Shibe Park (1-1) | 8-16 | |
| » Starters: Bernie Boland vs Scott Perry | Eighth | 8 out |
| Friday, May 24 |
| » Tied Senators, 2-2 | Griffith Stadium (0-0) | 8-16 | |
| » Starters: Eric Erickson vs Harry Harper | Eighth | 8 out |
| Saturday, May 25 |
| » Defeated Senators (13-19), 1-0 | Griffith Stadium (1-0) | 9-16 | Won 2 |
| » Starters: Hooks Dauss vs Jim Shaw | Eighth | 8 out |
| Sunday, May 26 |
| » Lost to Senators (14-19), 4-0 | Griffith Stadium (1-1) | 9-17 | |
| » Starters: Rudy Kallio vs Walter Johnson | Eighth | 8½ out |
| Monday, May 27 |
| » Lost to Senators (15-19), 7-4 | Griffith Stadium (1-2) | 9-18 | Lost 2 |
| » Starters: Bernie Boland vs Doc Ayers | Eighth | 8½ out |
| Tuesday, May 28 |
| » Defeated Senators (15-20), 4-2 | Griffith Stadium (2-2) | 10-18 | |
| » Starters: Eric Erickson vs Jim Shaw | Eighth | 8½ out |
| Wednesday, May 29 |
| » Lost to Indians (20-17), 7-1 | League Park II (0-3) | 10-19 | |
| » Starters: Bill James vs Fritz Coumbe | Eighth | 10 out |
| Thursday, May 30 |
| » Defeated Browns (17-16), 2-1 | Tiger Stadium (6-5) | 11-19 | |
| » Starters: Bert Gallia vs Hooks Dauss | Eighth | 9½ out |
| Friday, May 31 |
| » Lost to Browns (18-16), 3-2 | Tiger Stadium (6-6) | 11-20 | |
| » Starters: Urban Shocker vs Bernie Boland | Eighth | 10 out |
| Saturday, June 1 |
| » Defeated Red Sox (25-15), 4-3 | Tiger Stadium (7-6) | 12-20 | |
| » Starters: Bullet Joe Bush vs Rudy Kallio | Eighth | 9 out |
| Sunday, June 2 |
| » Defeated Red Sox (25-16), 4-3 | Tiger Stadium (8-6) | 13-20 | Won 2 |
| » Starters: Babe Ruth vs Eric Erickson | Seventh | 8 out |
| Monday, June 3 |
| » Lost to Red Sox (26-16), 5-0 | Tiger Stadium (8-7) | 13-21 | |
| » Starters: Dutch Leonard vs Hooks Dauss | Eighth | 9 out |
| Tuesday, June 4 |
| » Lost to Red Sox (27-16), 7-6 | Tiger Stadium (8-8) | 13-22 | Lost 2 |
| » Starters: Carl Mays vs Bill James | Eighth | 10 out |
| Wednesday, June 5 |
| » Lost to Senators (20-24), 5-4 | Tiger Stadium (8-9) | 13-23 | Lost 3 |
| » Starters: Harry Harper vs Rudy Kallio | Eighth | 10 out |
| Thursday, June 6 |
| » Lost to Senators (21-24), 3-2 | Tiger Stadium (8-10) | 13-24 | Lost 4 |
| » Starters: Nick Altrock vs George Cunningham | Eighth | 11 out |
| Friday, June 7 |
| » Defeated Senators (21-25), 9-6 | Tiger Stadium (9-10) | 14-24 | |
| » Starters: Doc Ayers vs Bernie Boland | Eighth | 10 out |
| Saturday, June 8 |
| » Lost to Senators (22-25), 5-3 | Tiger Stadium (9-11) | 14-25 | |
| » Starters: Harry Harper vs Rudy Kallio | Eighth | 10 out |
| Sunday, June 9 |
| » Lost to Senators (23-25), 2-0 | Tiger Stadium (9-12) | 14-26 | Lost 2 |
| » Starters: Walter Johnson vs Bernie Boland | Eighth | 11 out |
| Monday, June 10 |
| » Defeated Athletics (17-27), 6-4 | Tiger Stadium (10-12) | 15-26 | |
| » Starters: Elmer Myers vs Hooks Dauss | Eighth | 11 out |
| Tuesday, June 11 |
| » Lost to Athletics (18-27), 8-1 | Tiger Stadium (10-13) | 15-27 | |
| » Starters: Willie Adams vs George Cunningham | Eighth | 11 out |
| Wednesday, June 12 |
| » Lost to Athletics (19-27), 4-3 | Tiger Stadium (10-14) | 15-28 | Lost 2 |
| » Starters: Vean Gregg vs Rudy Kallio | Eighth | 12 out |
| Thursday, June 13 |
| » Defeated Athletics (19-28), 10-2 | Tiger Stadium (11-14) | 16-28 | |
| » Starters: Elmer Myers vs Bernie Boland | Eighth | 12 out |
| Friday, June 14 |
| » Lost to Yankees (29-21), 11-6 | Tiger Stadium (11-15) | 16-29 | |
| » Starters: Hank Thormahlen vs Hooks Dauss | Eighth | 12 out |
| Saturday, June 15 |
| » Defeated Yankees (29-22), 4-0 | Tiger Stadium (12-15) | 17-29 | |
| » Starters: Allen Russell vs Rudy Kallio | Eighth | 12 out |
| Sunday, June 16 |
| » Lost to Yankees (30-22), 5-2 | Tiger Stadium (12-16) | 17-30 | |
| » Starters: Ray Caldwell vs Eric Erickson | Eighth | 12 out |
| Monday, June 17 |
| » Tied Yankees, 5-5 | Tiger Stadium (12-16) | 17-30 | |
| » Starters: Slim Love vs George Cunningham | Eighth | 12½ out |
| Tuesday, June 18 |
| » Defeated Browns (25-27), 6-2 | Sportsman's Park III (1-2) | 18-30 | |
| » Starters: Hooks Dauss vs Lefty Leifield | Seventh | 11½ out |
| » Defeated Browns (25-28), 3-1 | Sportsman's Park III (2-2) | 19-30 | Won 2 |
| » Starters: Bernie Boland vs Allen Sothoron | Seventh | 11½ out |
| Wednesday, June 19 |
| » Defeated Browns (25-29), 7-5 | Sportsman's Park III (3-2) | 20-30 | Won 3 |
| » Starters: Rudy Kallio vs Tom Rogers | Seventh | 10½ out |
| Thursday, June 20 |
| » Major-league debuts: Johnny Mostil (White Sox) |
| Saturday, June 22 |
| » Defeated Browns (25-30), 2-1 | Tiger Stadium (13-16) | 21-30 | Won 4 |
| » Starters: Urban Shocker vs Hooks Dauss | Seventh | 10 out |
| » Defeated Browns (25-31), 6-3 | Tiger Stadium (14-16) | 22-30 | Won 5 |
| » Starters: Grover Lowdermilk vs Rudy Kallio | Seventh | 10 out |
| Sunday, June 23 |
| » Lost to Browns (26-31), 4-1 | Tiger Stadium (14-17) | 22-31 | |
| » Starters: Allen Sothoron vs Bernie Boland | Seventh | 11 out |
| » Lost to Browns (27-31), 4-2 | Tiger Stadium (14-18) | 22-32 | Lost 2 |
| » Starters: Dave Davenport vs Harry Coveleski | Seventh | 11 out |
| Monday, June 24 |
| » Defeated White Sox (27-28), 6-2 | Tiger Stadium (15-18) | 23-32 | |
| » Starters: Eddie Cicotte vs Bill James | Seventh | 10 out |
| Tuesday, June 25 |
| » Defeated White Sox (27-29), 4-2 | Tiger Stadium (16-18) | 24-32 | Won 2 |
| » Starters: Reb Russell vs George Cunningham | Seventh | 10 out |
| Wednesday, June 26 |
| » Lost to White Sox (28-29), 3-0 | Tiger Stadium (16-19) | 24-33 | |
| » Starters: Frank Shellenback vs Hooks Dauss | Seventh | 10 out |
| Thursday, June 27 |
| » Defeated White Sox (28-30), 1-0 | Tiger Stadium (17-19) | 25-33 | |
| » Starters: Dave Danforth vs Bernie Boland | Seventh | 9 out |
| Friday, June 28 |
| » Lost to Indians (38-29), 3-1 | League Park II (0-4) | 25-34 | |
| » Starters: Rudy Kallio vs Fritz Coumbe | Seventh | 10 out |
| Saturday, June 29 |
| » Lost to Indians (39-29), 13-4 | League Park II (0-5) | 25-35 | Lost 2 |
| » Starters: Bill James vs Guy Morton | Seventh | 10 out |
| Sunday, June 30 |
| » Defeated Indians (39-30), 10-2 | League Park II (1-5) | 26-35 | |
| » Starters: Hooks Dauss vs Stan Coveleski | Seventh | 9½ out |
| » Defeated Indians (39-31), 2-0 | League Park II (2-5) | 27-35 | Won 2 |
| » Starters: Bernie Boland vs Jim Bagby | Seventh | 9½ out |
| Monday, July 1 |
| » Lost to Indians (40-31), 4-1 | League Park II (2-6) | 27-36 | |
| » Starters: George Cunningham vs Fritz Coumbe | Seventh | 10 out |
| Tuesday, July 2 |
| » Lost to White Sox (31-34), 8-2 | Comiskey Park I (1-1) | 27-37 | Lost 2 |
| » Starters: Bill James vs Eddie Cicotte | Seventh | 9½ out |
| » Defeated White Sox (31-35), 11-8 | Comiskey Park I (2-1) | 28-37 | |
| » Starters: Rudy Kallio vs Reb Russell | Seventh | 9½ out |
| Wednesday, July 3 |
| » Lost to White Sox (32-35), 9-5 | Comiskey Park I (2-2) | 28-38 | |
| » Starters: Bill Bailey vs Frank Shellenback | Seventh | 9½ out |
| Thursday, July 4 |
| » Lost to White Sox (33-35), 7-6 | Comiskey Park I (2-3) | 28-39 | Lost 2 |
| » Starters: Bernie Boland vs Dave Danforth | Seventh | 11½ out |
| » Lost to White Sox (34-35), 2-1 | Comiskey Park I (2-4) | 28-40 | Lost 3 |
| » Starters: Bill James vs Joe Benz | Seventh | 11½ out |
| Saturday, July 6 |
| » Defeated Athletics (25-44), 5-2 | Shibe Park (2-1) | 29-40 | |
| » Starters: Hooks Dauss vs Vean Gregg | Seventh | 11½ out |
| » Lost to Athletics (26-44), 7-1 | Shibe Park (2-2) | 29-41 | |
| » Starters: Bill Bailey vs Scott Perry | Seventh | 11½ out |
| Monday, July 8 |
| » Lost to Athletics (27-44), 16-9 | Shibe Park (2-3) | 29-42 | Lost 2 |
| » Starters: Rudy Kallio vs Mule Watson | Seventh | 12 out |
| Tuesday, July 9 |
| » Lost to Athletics (28-44), 3-1 | Shibe Park (2-4) | 29-43 | Lost 3 |
| » Starters: Bernie Boland vs Vean Gregg | Seventh | 12½ out |
| » Defeated Athletics (28-45), 5-4 | Shibe Park (3-4) | 30-43 | |
| » Starters: Bill James vs Scott Perry | Seventh | 12½ out |
| Wednesday, July 10 |
| » Lost to Athletics (29-45), 5-1 | Shibe Park (3-5) | 30-44 | |
| » Starters: Rudy Kallio vs Scott Perry | Sixth | 13½ out |
| Thursday, July 11 |
| » Defeated Senators (40-38), 8-6 | Griffith Stadium (3-2) | 31-44 | |
| » Starters: George Cunningham vs Walter Johnson | Sixth | 13½ out |
| Friday, July 12 |
| » Lost to Senators (41-38), 5-4 | Griffith Stadium (3-3) | 31-45 | |
| » Starters: Hooks Dauss vs Jim Shaw | Seventh | 14½ out |
| Saturday, July 13 |
| » Defeated Senators (41-39), 1-0 | Griffith Stadium (4-3) | 32-45 | |
| » Starters: Bill James vs Harry Harper | Seventh | 13½ out |
| Sunday, July 14 |
| » Defeated Senators (41-40), 7-0 | Griffith Stadium (5-3) | 33-45 | Won 2 |
| » Starters: Bernie Boland vs Doc Ayers | Seventh | 13 out |
| Tuesday, July 16 |
| » Defeated Yankees (43-37), 12-1 | Polo Grounds V (2-2) | 34-45 | Won 3 |
| » Starters: Hooks Dauss vs Ray Caldwell | Sixth | 13 out |
| » Defeated Yankees (43-38), 4-1 | Polo Grounds V (3-2) | 35-45 | Won 4 |
| » Starters: Bernie Boland vs Slim Love | Sixth | 13 out |
| Thursday, July 18 |
| » Defeated Yankees (43-39), 4-1 | Polo Grounds V (4-2) | 36-45 | Won 5 |
| » Starters: Bill James vs Hank Thormahlen | Seventh | 13½ out |
| » Lost to Yankees (44-39), 3-2 | Polo Grounds V (4-3) | 36-46 | |
| » Starters: Rudy Kallio vs Happy Finneran | Seventh | 13½ out |
| Future Tiger Al Lyons is born in St. Joseph, MO. |
| Friday, July 19 |
| » Lost to Red Sox (52-34), 5-0 | Fenway Park (0-5) | 36-47 | Lost 2 |
| » Starters: Bill Bailey vs Carl Mays | Sixth | 14½ out |
| Saturday, July 20 |
| » Lost to Red Sox (53-34), 5-1 | Fenway Park (0-6) | 36-48 | Lost 3 |
| » Starters: Hooks Dauss vs Sad Sam Jones | Seventh | 15½ out |
| Monday, July 22 |
| » Lost to Red Sox (54-34), 1-0 | Fenway Park (0-7) | 36-49 | Lost 4 |
| » Starters: Bill James vs Bullet Joe Bush | Eighth | 17½ out |
| » Lost to Red Sox (55-34), 3-0 | Fenway Park (0-8) | 36-50 | Lost 5 |
| » Starters: Rudy Kallio vs Carl Mays | Eighth | 17½ out |
| Thursday, July 25 |
| » Defeated Athletics (36-50), 7-3 | Tiger Stadium (18-19) | 37-50 | |
| » Starters: Scott Perry vs Hooks Dauss | Sixth | 16½ out |
| Friday, July 26 |
| » Defeated Athletics (36-51), 2-1 | Tiger Stadium (19-19) | 38-50 | Won 2 |
| » Starters: Vean Gregg vs Bernie Boland | Seventh | 15½ out |
| Saturday, July 27 |
| » Lost to Athletics (37-51), 5-3 | Tiger Stadium (19-20) | 38-51 | |
| » Starters: Mule Watson vs Bill James | Seventh | 16½ out |
| Sunday, July 28 |
| » Defeated Athletics (37-52), 6-0 | Tiger Stadium (20-20) | 39-51 | |
| » Starters: Willie Adams vs Rudy Kallio | Seventh | 15 out |
| » Defeated Athletics (37-53), 6-2 | Tiger Stadium (21-20) | 40-51 | Won 2 |
| » Starters: Scott Perry vs George Cunningham | Seventh | 15 out |
| Monday, July 29 |
| » Defeated Yankees (46-43), 3-2 | Tiger Stadium (22-20) | 41-51 | Won 3 |
| » Starters: George Mogridge vs Hooks Dauss | Seventh | 15 out |
| Tuesday, July 30 |
| » Defeated Yankees (46-44), 3-0 | Tiger Stadium (23-20) | 42-51 | Won 4 |
| » Starters: Slim Love vs Bernie Boland | Sixth | 15 out |
| Wednesday, July 31 |
| » Lost to Yankees (47-44), 5-3 | Tiger Stadium (23-21) | 42-52 | |
| » Starters: Hank Thormahlen vs Rudy Kallio | Sixth | 15½ out |
| » Defeated Yankees (47-45), 6-2 | Tiger Stadium (24-21) | 43-52 | |
| » Starters: Ray Keating vs Bill Bailey | Sixth | 15½ out |
| Thursday, August 1 |
| » Lost to Yankees (48-45), 7-0 | Tiger Stadium (24-22) | 43-53 | |
| » Starters: Ray Caldwell vs Charley Hall | Sixth | 16½ out |
| Friday, August 2 |
| » Lost to Senators (53-44), 5-0 | Tiger Stadium (24-23) | 43-54 | Lost 2 |
| » Starters: Harry Harper vs Hooks Dauss | Sixth | 16½ out |
| Saturday, August 3 |
| » Lost to Senators (54-44), 10-1 | Tiger Stadium (24-24) | 43-55 | Lost 3 |
| » Starters: Jim Shaw vs Bernie Boland | Seventh | 16½ out |
| Sunday, August 4 |
| » Lost to Senators (55-44), 7-0 | Tiger Stadium (24-25) | 43-56 | Lost 4 |
| » Starters: Doc Ayers vs Rudy Kallio | Seventh | 16½ out |
| » Defeated Senators (55-45), 7-6 | Tiger Stadium (25-25) | 44-56 | |
| » Starters: Walter Johnson vs Deacon Jones | Seventh | 16½ out |
| Future Tiger Don Kolloway is born in Posen, IL. |
| Tuesday, August 6 |
| » Lost to Red Sox (62-40), 7-5 | Tiger Stadium (25-26) | 44-57 | |
| » Starters: Carl Mays vs George Cunningham | Seventh | 17½ out |
| Wednesday, August 7 |
| » Defeated Red Sox (62-41), 11-8 | Tiger Stadium (26-26) | 45-57 | |
| » Starters: Bullet Joe Bush vs Deacon Jones | Seventh | 16½ out |
| » Major-league debuts: Bill Pertica (Red Sox) |
| Thursday, August 8 |
| » Lost to Red Sox (63-41), 4-1 | Tiger Stadium (26-27) | 45-58 | |
| » Starters: Babe Ruth vs Bernie Boland | Seventh | 17½ out |
| Future Tiger Marlin Stuart is born in Paragould, AR. |
| Saturday, August 10 |
| » Defeated Browns (47-55), 2-1 | Sportsman's Park III (4-2) | 46-58 | |
| » Starters: George Cunningham vs Tom Rogers | Seventh | 16 out |
| Sunday, August 11 |
| » Lost to Browns (48-55), 5-2 | Sportsman's Park III (4-3) | 46-59 | |
| » Starters: Hooks Dauss vs Rasty Wright | Seventh | 16 out |
| » Defeated Browns (48-56), 5-1 | Sportsman's Park III (5-3) | 47-59 | |
| » Starters: Rudy Kallio vs Lefty Leifield | Seventh | 16 out |
| Wednesday, August 14 |
| » Defeated Senators (60-49), 5-3 | Griffith Stadium (6-3) | 48-59 | Won 2 |
| » Starters: Bernie Boland vs Jim Shaw | Seventh | 15½ out |
| Thursday, August 15 |
| » Lost to Senators (61-49), 6-2 | Griffith Stadium (6-4) | 48-60 | |
| » Starters: George Cunningham vs Eddie Matteson | Seventh | 15½ out |
| Friday, August 16 |
| » Defeated Senators (61-50), 8-7 | Griffith Stadium (7-4) | 49-60 | |
| » Starters: Rudy Kallio vs Harry Harper | Seventh | 15½ out |
| Saturday, August 17 |
| » Lost to Athletics (43-68), 8-3 | Shibe Park (3-6) | 49-61 | |
| » Starters: Hooks Dauss vs Mule Watson | Seventh | 17 out |
| » Lost to Athletics (44-68), 4-3 | Shibe Park (3-7) | 49-62 | Lost 2 |
| » Starters: Bernie Boland vs Scott Perry | Seventh | 17 out |
| Monday, August 19 |
| » Lost to Athletics (45-68), 9-8 | Shibe Park (3-8) | 49-63 | Lost 3 |
| » Starters: Deacon Jones vs Mule Watson | Seventh | 18 out |
| Wednesday, August 21 |
| » Lost to Yankees (54-56), 5-2 | Polo Grounds V (4-4) | 49-64 | Lost 4 |
| » Starters: Hooks Dauss vs George Mogridge | Seventh | 18½ out |
| Thursday, August 22 |
| » Lost to Yankees (55-56), 5-3 | Polo Grounds V (4-5) | 49-65 | Lost 5 |
| » Starters: George Cunningham vs Slim Love | Seventh | 18½ out |
| Saturday, August 24 |
| » Defeated Yankees (55-57), 5-4 | Polo Grounds V (5-5) | 50-65 | |
| » Starters: Bernie Boland vs Happy Finneran | Seventh | 19½ out |
| » Lost to Yankees (56-57), 2-0 | Polo Grounds V (5-6) | 50-66 | |
| » Starters: Hooks Dauss vs George Mogridge | Seventh | 19½ out |
| Monday, August 26 |
| » Defeated Red Sox (70-48), 6-3 | Fenway Park (1-8) | 51-66 | |
| » Starters: George Cunningham vs Carl Mays | Seventh | 18½ out |
| Tuesday, August 27 |
| » Defeated Red Sox (70-49), 2-1 | Fenway Park (2-8) | 52-66 | Won 2 |
| » Starters: Rudy Kallio vs Bullet Joe Bush | Seventh | 17½ out |
| Wednesday, August 28 |
| » Lost to Red Sox (71-49), 3-0 | Fenway Park (2-9) | 52-67 | |
| » Starters: Hooks Dauss vs Sad Sam Jones | Seventh | 18½ out |
| Friday, August 30 |
| » Lost to Indians (70-54), 2-1 | Tiger Stadium (26-28) | 52-68 | Lost 2 |
| » Starters: Stan Coveleski vs George Cunningham | Seventh | 20½ out |
| » Lost to Indians (71-54), 4-2 | Tiger Stadium (26-29) | 52-69 | Lost 3 |
| » Starters: Jim Bagby vs Deacon Jones | Seventh | 20½ out |
| Saturday, August 31 |
| » Lost to Browns (57-63), 5-3 | Sportsman's Park III (5-4) | 52-70 | Lost 4 |
| » Starters: Rudy Kallio vs Tom Rogers | Seventh | 21 out |
| Sunday, September 1 |
| » Defeated Browns (57-64), 7-5 | Sportsman's Park III (6-4) | 53-70 | |
| » Starters: Hooks Dauss vs Dave Davenport | Seventh | 21 out |
| » Lost to Browns (58-64), 6-2 | Sportsman's Park III (6-5) | 53-71 | |
| » Starters: George Cunningham vs Rasty Wright | Seventh | 21 out |
| Monday, September 2 |
| » Defeated White Sox (57-66), 11-5 | Tiger Stadium (27-29) | 54-71 | |
| » Starters: Dave Danforth vs Bernie Boland | Seventh | 20 out |
| » Defeated White Sox (57-67), 7-3 | Tiger Stadium (28-29) | 55-71 | Won 2 |
| » Starters: Eddie Cicotte vs Bill Donovan | Seventh | 20 out |
| Monday, October 7 |
| Former Tiger Bun Troy dies in Petit Maujouym, France at the age of 31. |
Game information provided by Retrosheet (www.retrosheet.org) |
