| Saturday, January 20 |
| Future White Sox Joe Dobson is born in Durant, OK. |
| Thursday, March 1 |
| Future White Sox Ike Pearson is born in Grenada, MS. |
| Friday, March 23 |
| Former White Sox Art Weaver dies in Denver, CO at the age of 38. |
| Wednesday, April 11 |
| » Defeated Browns (0-1), 7-2 | Sportsman's Park III (1-0) | 1-0 | |
| » Starters: Lefty Williams vs Earl Hamilton | First | -- |
| » Major-league debuts: Swede Risberg (White Sox) |
| Friday, April 13 |
| » Lost to Browns (1-1), 4-3 | Sportsman's Park III (1-1) | 1-1 | |
| » Starters: Red Faber vs Ernie Koob | Second | 1 out |
| Saturday, April 14 |
| » Defeated Browns (1-2), 11-0 | Sportsman's Park III (2-1) | 2-1 | |
| » Starters: Eddie Cicotte vs Earl Hamilton | First | -- |
| » Major-league debuts: Tom Rogers (Browns) |
| Sunday, April 15 |
| » Defeated Tigers (1-3), 6-2 | Tiger Stadium (1-0) | 3-1 | Won 2 |
| » Starters: Jim Scott vs Harry Coveleski | First | -- |
| Monday, April 16 |
| » Defeated Tigers (1-4), 4-0 | Tiger Stadium (2-0) | 4-1 | Won 3 |
| » Starters: Red Faber vs Deacon Jones | First | -- |
| Tuesday, April 17 |
| » Defeated Tigers (1-5), 4-2 | Tiger Stadium (3-0) | 5-1 | Won 4 |
| » Starters: Dave Danforth vs Howard Ehmke | First | -- |
| Thursday, April 19 |
| » Lost to Browns (4-3), 6-2 | Comiskey Park I (0-1) | 5-2 | |
| » Starters: Eddie Plank vs Jim Scott | First | -- |
| Friday, April 20 |
| » Defeated Browns (4-4), 5-2 | Comiskey Park I (1-1) | 6-2 | |
| » Starters: Allen Sothoron vs Eddie Cicotte | First | -- |
| Saturday, April 21 |
| » Defeated Browns (4-5), 2-0 | Comiskey Park I (2-1) | 7-2 | Won 2 |
| » Starters: Ernie Koob vs Red Faber | First | -- |
| Sunday, April 22 |
| » Defeated Browns (4-6), 3-2 | Comiskey Park I (3-1) | 8-2 | Won 3 |
| » Starters: Earl Hamilton vs Dave Danforth | First | -- |
| Monday, April 23 |
| Future White Sox Tony Lupien is born in Chelmsford, MA. |
| Tuesday, April 24 |
| » Defeated Indians (5-6), 1-0 | Comiskey Park I (4-1) | 9-2 | Won 4 |
| » Starters: Stan Coveleski vs Jim Scott | First | -- |
| Wednesday, April 25 |
| » Lost to Indians (6-6), 4-1 | Comiskey Park I (4-2) | 9-3 | |
| » Starters: Fritz Coumbe vs Eddie Cicotte | First | -- |
| Thursday, April 26 |
| » Lost to Indians (7-6), 3-0 | Comiskey Park I (4-3) | 9-4 | Lost 2 |
| » Starters: Jim Bagby vs Red Faber | First | -- |
| Future White Sox Virgil Trucks is born in Birmingham, AL. |
| Friday, April 27 |
| » Lost to Indians (8-6), 2-1 | Comiskey Park I (4-4) | 9-5 | Lost 3 |
| » Starters: Ed Klepfer vs Lefty Williams | First | -- |
| Saturday, April 28 |
| » Defeated Tigers (4-9), 2-1 | Comiskey Park I (5-4) | 10-5 | |
| » Starters: Harry Coveleski vs Jim Scott | First | -- |
| Sunday, April 29 |
| » Lost to Tigers (5-9), 3-0 | Comiskey Park I (5-5) | 10-6 | |
| » Starters: Willie Mitchell vs Red Faber | Second | 2 out |
| Wednesday, May 2 |
| » Defeated Indians (8-10), 8-3 | League Park II (1-0) | 11-6 | |
| » Starters: Lefty Williams vs Fritz Coumbe | Second | 2 out |
| Thursday, May 3 |
| » Lost to Indians (9-10), 2-1 | League Park II (1-1) | 11-7 | |
| » Starters: Jim Scott vs Ed Klepfer | Second | 2 out |
| Saturday, May 5 |
| » Lost to Browns (9-8), 1-0 | Sportsman's Park III (2-2) | 11-8 | Lost 2 |
| » Starters: Eddie Cicotte vs Ernie Koob | Second | 2½ out |
| Sunday, May 6 |
| » Lost to Browns (10-8), 8-4 | Sportsman's Park III (2-3) | 11-9 | Lost 3 |
| » Starters: Reb Russell vs Allen Sothoron | Fourth | 3½ out |
| » Lost to Browns (11-8), 3-0 | Sportsman's Park III (2-4) | 11-10 | Lost 4 |
| » Starters: Joe Benz vs Bob Groom | Fourth | 3½ out |
| Future White Sox Mike McCormick is born in Angels Camp, CA. |
| Monday, May 7 |
| Future White Sox Al Papai is born in Divernon, IL. |
| Tuesday, May 8 |
| » Defeated Browns (11-9), 4-3 | Sportsman's Park III (3-4) | 12-10 | |
| » Starters: Jim Scott vs Dave Davenport | Third | 4 out |
| » Defeated Browns (11-10), 9-7 | Sportsman's Park III (4-4) | 13-10 | Won 2 |
| » Starters: Lefty Williams vs Allen Sothoron | Third | 4 out |
| Wednesday, May 9 |
| » Defeated Browns (11-11), 4-2 | Sportsman's Park III (5-4) | 14-10 | Won 3 |
| » Starters: Lefty Williams vs Bob Groom | Third | 3½ out |
| Thursday, May 10 |
| » Lost to Yankees (11-7), 1-0 | Comiskey Park I (5-6) | 14-11 | |
| » Starters: Bob Shawkey vs Reb Russell | Third | 3½ out |
| Friday, May 11 |
| » Lost to Yankees (12-7), 6-1 | Comiskey Park I (5-7) | 14-12 | Lost 2 |
| » Starters: Ray Caldwell vs Dave Danforth | Third | 3½ out |
| Saturday, May 12 |
| » Defeated Yankees (12-8), 2-1 | Comiskey Park I (6-7) | 15-12 | |
| » Starters: George Mogridge vs Jim Scott | Third | 3½ out |
| Sunday, May 13 |
| » Defeated Yankees (12-9), 1-0 | Comiskey Park I (7-7) | 16-12 | Won 2 |
| » Starters: Nick Cullop vs Eddie Cicotte | Second | 3½ out |
| Monday, May 14 |
| » Defeated Athletics (7-15), 6-2 | Comiskey Park I (8-7) | 17-12 | Won 3 |
| » Starters: Walter Anderson vs Reb Russell | Third | 3½ out |
| Tuesday, May 15 |
| » Defeated Athletics (7-16), 11-0 | Comiskey Park I (9-7) | 18-12 | Won 4 |
| » Starters: Walt Johnson vs Joe Benz | Third | 3½ out |
| Wednesday, May 16 |
| » Defeated Athletics (7-17), 3-2 | Comiskey Park I (10-7) | 19-12 | Won 5 |
| » Starters: Bullet Joe Bush vs Lefty Williams | Third | 3½ out |
| Thursday, May 17 |
| » Defeated Athletics (7-18), 7-0 | Comiskey Park I (11-7) | 20-12 | Won 6 |
| » Starters: Cy Falkenberg vs Eddie Cicotte | Third | 3½ out |
| Friday, May 18 |
| » Defeated Red Sox (17-9), 8-2 | Comiskey Park I (12-7) | 21-12 | Won 7 |
| » Starters: Babe Ruth vs Reb Russell | Second | 3½ out |
| Saturday, May 19 |
| » Defeated Red Sox (17-10), 8-2 | Comiskey Park I (13-7) | 22-12 | Won 8 |
| » Starters: Dutch Leonard vs Lefty Williams | Second | 4 out |
| Sunday, May 20 |
| » Lost to Red Sox (18-10), 2-1 | Comiskey Park I (13-8) | 22-13 | |
| » Starters: Carl Mays vs Jim Scott | Third | 3½ out |
| Wednesday, May 23 |
| » Defeated Senators (13-18), 2-1 | Comiskey Park I (14-8) | 23-13 | |
| » Starters: Jim Shaw vs Eddie Cicotte | Second | 3½ out |
| Thursday, May 24 |
| » Defeated Senators (13-19), 1-0 | Comiskey Park I (15-8) | 24-13 | Won 2 |
| » Starters: George Dumont vs Reb Russell | Second | 3½ out |
| Friday, May 25 |
| » Defeated Senators (13-20), 5-1 | Comiskey Park I (16-8) | 25-13 | Won 3 |
| » Starters: Harry Harper vs Joe Benz | Second | 3½ out |
| Saturday, May 26 |
| » Tied Senators, 1-1 | Comiskey Park I (16-8) | 25-13 | |
| » Starters: Bert Gallia vs Jim Scott | Second | 3 out |
| Sunday, May 27 |
| » Defeated Senators (13-21), 4-1 | Comiskey Park I (17-8) | 26-13 | Won 4 |
| » Starters: Walter Johnson vs Eddie Cicotte | Second | 3½ out |
| Tuesday, May 29 |
| » Defeated Browns (15-23), 4-2 | Comiskey Park I (18-8) | 27-13 | Won 5 |
| » Starters: Bob Groom vs Reb Russell | Second | 3 out |
| Saturday, June 2 |
| » Defeated Athletics (13-24), 4-0 | Shibe Park (1-0) | 28-13 | Won 6 |
| » Starters: Eddie Cicotte vs Bullet Joe Bush | Second | 1 out |
| Monday, June 4 |
| » Defeated Athletics (13-25), 4-2 | Shibe Park (2-0) | 29-13 | Won 7 |
| » Starters: Reb Russell vs Win Noyes | Second | 1 out |
| Tuesday, June 5 |
| » Defeated Athletics (13-26), 6-3 | Shibe Park (3-0) | 30-13 | Won 8 |
| » Starters: Joe Benz vs Rube Schauer | Second | 1 out |
| Wednesday, June 6 |
| » Lost to Senators (16-27), 3-0 | Griffith Stadium (0-1) | 30-14 | |
| » Starters: Eddie Cicotte vs George Dumont | Second | 1 out |
| Thursday, June 7 |
| » Lost to Senators (17-27), 1-0 | Griffith Stadium (0-2) | 30-15 | Lost 2 |
| » Starters: Reb Russell vs Walter Johnson | Second | 1½ out |
| Friday, June 8 |
| » Defeated Senators (17-28), 11-4 | Griffith Stadium (1-2) | 31-15 | |
| » Starters: Joe Benz vs Jim Shaw | First | -- |
| Saturday, June 9 |
| » Defeated Senators (17-29), 5-4 | Griffith Stadium (2-2) | 32-15 | Won 2 |
| » Starters: Jim Scott vs Harry Harper | First | -- |
| Sunday, June 10 |
| » Defeated Indians (26-25), 10-4 | League Park II (2-1) | 33-15 | Won 3 |
| » Starters: Lefty Williams vs Fritz Coumbe | First | -- |
| Tuesday, June 12 |
| » Lost to Yankees (25-20), 4-3 | Polo Grounds V (0-1) | 33-16 | |
| » Starters: Eddie Cicotte vs George Mogridge | First | -- |
| Wednesday, June 13 |
| » Lost to Yankees (26-20), 7-6 | Polo Grounds V (0-2) | 33-17 | Lost 2 |
| » Starters: Reb Russell vs Nick Cullop | First | -- |
| Friday, June 15 |
| » Defeated Red Sox (30-18), 8-0 | Fenway Park (1-0) | 34-17 | |
| » Starters: Lefty Williams vs Ernie Shore | First | -- |
| Saturday, June 16 |
| » Defeated Red Sox (30-19), 7-2 | Fenway Park (2-0) | 35-17 | Won 2 |
| » Starters: Eddie Cicotte vs Babe Ruth | First | -- |
| Monday, June 18 |
| » Lost to Red Sox (31-19), 6-4 | Fenway Park (2-1) | 35-18 | |
| » Starters: Reb Russell vs Carl Mays | First | -- |
| » Lost to Red Sox (32-19), 8-7 | Fenway Park (2-2) | 35-19 | Lost 2 |
| » Starters: Jim Scott vs Rube Foster | First | -- |
| Wednesday, June 20 |
| » Defeated Indians (28-29), 3-2 | Comiskey Park I (19-8) | 36-19 | |
| » Starters: Stan Coveleski vs Lefty Williams | First | -- |
| Thursday, June 21 |
| » Lost to Indians (29-29), 1-0 | Comiskey Park I (19-9) | 36-20 | |
| » Starters: Jim Bagby vs Eddie Cicotte | First | -- |
| Friday, June 22 |
| » Defeated Indians (29-30), 4-1 | Comiskey Park I (20-9) | 37-20 | |
| » Starters: Otis Lambeth vs Red Faber | First | -- |
| Saturday, June 23 |
| » Defeated Indians (29-31), 2-1 | Comiskey Park I (21-9) | 38-20 | Won 2 |
| » Starters: Guy Morton vs Joe Benz | First | -- |
| Sunday, June 24 |
| » Defeated Indians (29-32), 1-0 | Comiskey Park I (22-9) | 39-20 | Won 3 |
| » Starters: Joe Boehling vs Dave Danforth | First | -- |
| Tuesday, June 26 |
| » Lost to Tigers (29-27), 9-2 | Comiskey Park I (22-10) | 39-21 | |
| » Starters: Willie Mitchell vs Red Faber | First | -- |
| » Defeated Tigers (29-28), 4-3 | Comiskey Park I (23-10) | 40-21 | |
| » Starters: Bill James vs Lefty Williams | First | -- |
| Wednesday, June 27 |
| » Defeated Tigers (29-29), 5-2 | Comiskey Park I (24-10) | 41-21 | Won 2 |
| » Starters: Hooks Dauss vs Eddie Cicotte | First | -- |
| » Defeated Tigers (29-30), 3-2 | Comiskey Park I (25-10) | 42-21 | Won 3 |
| » Starters: Howard Ehmke vs Dave Danforth | First | -- |
| Thursday, June 28 |
| » Lost to Tigers (30-30), 6-5 | Comiskey Park I (25-11) | 42-22 | |
| » Starters: Bernie Boland vs Reb Russell | First | -- |
| Friday, June 29 |
| » Defeated Indians (33-34), 3-1 | League Park II (3-1) | 43-22 | |
| » Starters: Red Faber vs Stan Coveleski | First | -- |
| Saturday, June 30 |
| » Lost to Indians (34-34), 11-1 | League Park II (3-2) | 43-23 | |
| » Starters: Lefty Williams vs Jim Bagby | First | -- |
| Sunday, July 1 |
| » Lost to Indians (35-34), 5-4 | League Park II (3-3) | 43-24 | Lost 2 |
| » Starters: Eddie Cicotte vs Guy Morton | First | -- |
| Monday, July 2 |
| » Defeated Indians (35-35), 4-3 | League Park II (4-3) | 44-24 | |
| » Starters: Dave Danforth vs Joe Boehling | First | -- |
| Tuesday, July 3 |
| » Defeated Tigers (34-33), 5-1 | Tiger Stadium (4-0) | 45-24 | Won 2 |
| » Starters: Red Faber vs Harry Coveleski | First | -- |
| Wednesday, July 4 |
| » Defeated Tigers (34-34), 4-3 | Tiger Stadium (5-0) | 46-24 | Won 3 |
| » Starters: Eddie Cicotte vs Bill James | First | -- |
| » Defeated Tigers (34-35), 4-3 | Tiger Stadium (6-0) | 47-24 | Won 4 |
| » Starters: Lefty Williams vs Willie Mitchell | First | -- |
| Thursday, July 5 |
| » Lost to Tigers (35-35), 11-6 | Tiger Stadium (6-1) | 47-25 | |
| » Starters: Dave Danforth vs Howard Ehmke | First | -- |
| Friday, July 6 |
| » Lost to Tigers (36-35), 4-1 | Tiger Stadium (6-2) | 47-26 | Lost 2 |
| » Starters: Red Faber vs Hooks Dauss | Second | 1 out |
| Saturday, July 7 |
| » Lost to Athletics (25-44), 4-2 | Comiskey Park I (25-12) | 47-27 | Lost 3 |
| » Starters: Elmer Myers vs Jim Scott | Second | 1 out |
| Sunday, July 8 |
| » Defeated Athletics (25-45), 8-4 | Comiskey Park I (26-12) | 48-27 | |
| » Starters: Rube Schauer vs Eddie Cicotte | First | -- |
| Monday, July 9 |
| » Lost to Athletics (26-45), 5-2 | Comiskey Park I (26-13) | 48-28 | |
| » Starters: Bullet Joe Bush vs Lefty Williams | First | -- |
| Tuesday, July 10 |
| » Lost to Athletics (27-45), 7-3 | Comiskey Park I (26-14) | 48-29 | Lost 2 |
| » Starters: Win Noyes vs Red Faber | First | -- |
| Thursday, July 12 |
| » Defeated Yankees (38-35), 2-1 | Comiskey Park I (27-14) | 49-29 | |
| » Starters: George Mogridge vs Eddie Cicotte | First | -- |
| » Defeated Yankees (38-36), 5-3 | Comiskey Park I (28-14) | 50-29 | Won 2 |
| » Starters: Bob Shawkey vs Jim Scott | First | -- |
| Friday, July 13 |
| » Lost to Yankees (39-36), 6-5 | Comiskey Park I (28-15) | 50-30 | |
| » Starters: Ray Caldwell vs Lefty Williams | First | -- |
| Saturday, July 14 |
| » Defeated Yankees (39-37), 4-1 | Comiskey Park I (29-15) | 51-30 | |
| » Starters: Slim Love vs Reb Russell | First | -- |
| Sunday, July 15 |
| » Lost to Senators (33-45), 6-5 | Comiskey Park I (29-16) | 51-31 | |
| » Starters: Jim Shaw vs Lefty Williams | Second | 1 out |
| Tuesday, July 17 |
| » Defeated Senators (33-46), 5-0 | Comiskey Park I (30-16) | 52-31 | |
| » Starters: George Dumont vs Eddie Cicotte | First | -- |
| » Defeated Senators (33-47), 3-2 | Comiskey Park I (31-16) | 53-31 | Won 2 |
| » Starters: Walter Johnson vs Red Faber | First | -- |
| Wednesday, July 18 |
| » Defeated Senators (33-48), 4-0 | Comiskey Park I (32-16) | 54-31 | Won 3 |
| » Starters: Harry Harper vs Joe Benz | First | -- |
| » Defeated Senators (33-49), 7-4 | Comiskey Park I (33-16) | 55-31 | Won 4 |
| » Starters: Bert Gallia vs Dave Danforth | First | -- |
| Thursday, July 19 |
| » Lost to Red Sox (52-32), 3-2 | Comiskey Park I (33-17) | 55-32 | |
| » Starters: Babe Ruth vs Lefty Williams | First | -- |
| Friday, July 20 |
| » Defeated Red Sox (52-33), 5-2 | Comiskey Park I (34-17) | 56-32 | |
| » Starters: Rube Foster vs Eddie Cicotte | First | -- |
| Saturday, July 21 |
| » Tied Red Sox, 5-5 | Comiskey Park I (34-17) | 56-32 | |
| » Starters: Dutch Leonard vs Red Faber | First | -- |
| Sunday, July 22 |
| » Defeated Red Sox (52-34), 2-0 | Comiskey Park I (35-17) | 57-32 | Won 2 |
| » Starters: Carl Mays vs Reb Russell | First | -- |
| Monday, July 23 |
| » Defeated Red Sox (52-35), 5-3 | Comiskey Park I (36-17) | 58-32 | Won 3 |
| » Starters: Ernie Shore vs Lefty Williams | First | -- |
| Future White Sox Ray Scarborough is born in Mount Gilead, NC. |
| Wednesday, July 25 |
| » Defeated Yankees (44-43), 4-1 | Polo Grounds V (1-2) | 59-32 | Won 4 |
| » Starters: Eddie Cicotte vs George Mogridge | First | -- |
| » Defeated Yankees (44-44), 5-1 | Polo Grounds V (2-2) | 60-32 | Won 5 |
| » Starters: Red Faber vs Ray Fisher | First | -- |
| Thursday, July 26 |
| » Lost to Yankees (45-44), 6-5 | Polo Grounds V (2-3) | 60-33 | |
| » Starters: Joe Benz vs Nick Cullop | First | -- |
| Friday, July 27 |
| » Defeated Yankees (45-45), 9-5 | Polo Grounds V (3-3) | 61-33 | |
| » Starters: Reb Russell vs Ray Caldwell | First | -- |
| Saturday, July 28 |
| » Lost to Yankees (46-45), 5-4 | Polo Grounds V (3-4) | 61-34 | |
| » Starters: Red Faber vs Allen Russell | First | -- |
| » Lost to Yankees (47-45), 4-3 | Polo Grounds V (3-5) | 61-35 | Lost 2 |
| » Starters: Jim Scott vs Bob Shawkey | First | -- |
| Monday, July 30 |
| » Lost to Red Sox (58-35), 3-1 | Fenway Park (2-3) | 61-36 | Lost 3 |
| » Starters: Lefty Williams vs Babe Ruth | First | -- |
| Tuesday, July 31 |
| » Lost to Red Sox (59-35), 5-2 | Fenway Park (2-4) | 61-37 | Lost 4 |
| » Starters: Eddie Cicotte vs Dutch Leonard | Second | 2 out |
| Wednesday, August 1 |
| » Defeated Red Sox (59-36), 4-0 | Fenway Park (3-4) | 62-37 | |
| » Starters: Reb Russell vs Carl Mays | First | -- |
| Thursday, August 2 |
| » Defeated Red Sox (59-37), 7-1 | Fenway Park (4-4) | 63-37 | Won 2 |
| » Starters: Red Faber vs Ernie Shore | First | -- |
| Friday, August 3 |
| » Defeated Athletics (35-59), 4-0 | Shibe Park (4-0) | 64-37 | Won 3 |
| » Starters: Jim Scott vs Socks Seibold | First | -- |
| Saturday, August 4 |
| » Defeated Athletics (35-60), 7-3 | Shibe Park (5-0) | 65-37 | Won 4 |
| » Starters: Joe Benz vs Elmer Myers | First | -- |
| » Defeated Athletics (35-61), 4-3 | Shibe Park (6-0) | 66-37 | Won 5 |
| » Starters: Lefty Williams vs Jing Johnson | First | -- |
| Monday, August 6 |
| » Lost to Athletics (36-61), 5-4 | Shibe Park (6-1) | 66-38 | |
| » Starters: Reb Russell vs Win Noyes | First | -- |
| Tuesday, August 7 |
| » Lost to Athletics (37-61), 8-1 | Shibe Park (6-2) | 66-39 | Lost 2 |
| » Starters: Red Faber vs Rube Schauer | First | -- |
| Wednesday, August 8 |
| » Lost to Senators (46-57), 2-0 | Griffith Stadium (2-3) | 66-40 | Lost 3 |
| » Starters: Eddie Cicotte vs Harry Harper | First | -- |
| Thursday, August 9 |
| » Defeated Senators (46-58), 3-2 | Griffith Stadium (3-3) | 67-40 | |
| » Starters: Joe Benz vs Bert Gallia | First | -- |
| Friday, August 10 |
| » Lost to Senators (47-58), 4-0 | Griffith Stadium (3-4) | 67-41 | |
| » Starters: Red Faber vs Walter Johnson | First | -- |
| Saturday, August 11 |
| » Lost to Senators (48-58), 3-2 | Griffith Stadium (3-5) | 67-42 | Lost 2 |
| » Starters: Eddie Cicotte vs Jim Shaw | First | -- |
| Sunday, August 12 |
| » Defeated Indians (60-52), 4-3 | League Park II (5-3) | 68-42 | |
| » Starters: Jim Scott vs Jim Bagby | First | -- |
| Tuesday, August 14 |
| » Defeated Indians (60-53), 3-2 | League Park II (6-3) | 69-42 | Won 2 |
| » Starters: Lefty Williams vs Stan Coveleski | First | -- |
| » Lost to Indians (61-53), 4-2 | League Park II (6-4) | 69-43 | |
| » Starters: Red Faber vs Guy Morton | First | -- |
| Wednesday, August 15 |
| » Defeated Indians (61-54), 5-4 | League Park II (7-4) | 70-43 | |
| » Starters: Eddie Cicotte vs Ed Klepfer | First | -- |
| Friday, August 17 |
| » Lost to Athletics (42-65), 9-7 | Comiskey Park I (36-18) | 70-44 | |
| » Starters: Rube Schauer vs Jim Scott | Second | 2½ out |
| Saturday, August 18 |
| » Defeated Athletics (42-66), 5-4 | Comiskey Park I (37-18) | 71-44 | |
| » Starters: Walter Anderson vs Lefty Williams | First | -- |
| Sunday, August 19 |
| » Defeated Athletics (42-67), 14-6 | Comiskey Park I (38-18) | 72-44 | Won 2 |
| » Starters: Elmer Myers vs Reb Russell | First | -- |
| Monday, August 20 |
| » Defeated Red Sox (68-45), 7-0 | Comiskey Park I (39-18) | 73-44 | Won 3 |
| » Starters: Rube Foster vs Red Faber | First | -- |
| » Lost to Red Sox (69-45), 3-1 | Comiskey Park I (39-19) | 73-45 | |
| » Starters: Carl Mays vs Eddie Cicotte | First | -- |
| Tuesday, August 21 |
| » Defeated Red Sox (69-46), 2-0 | Comiskey Park I (40-19) | 74-45 | |
| » Starters: Babe Ruth vs Reb Russell | First | -- |
| Wednesday, August 22 |
| » Lost to Red Sox (70-46), 5-1 | Comiskey Park I (40-20) | 74-46 | |
| » Starters: Dutch Leonard vs Lefty Williams | First | -- |
| Thursday, August 23 |
| » Defeated Senators (54-61), 6-0 | Comiskey Park I (41-20) | 75-46 | |
| » Starters: Jim Shaw vs Eddie Cicotte | First | -- |
| Saturday, August 25 |
| » Defeated Senators (54-62), 4-1 | Comiskey Park I (42-20) | 76-46 | Won 2 |
| » Starters: Walter Johnson vs Red Faber | First | -- |
| Sunday, August 26 |
| » Defeated Yankees (56-61), 8-3 | Comiskey Park I (43-20) | 77-46 | Won 3 |
| » Starters: George Mogridge vs Reb Russell | First | -- |
| Monday, August 27 |
| » Defeated Yankees (56-62), 3-0 | Comiskey Park I (44-20) | 78-46 | Won 4 |
| » Starters: Bob Shawkey vs Eddie Cicotte | First | -- |
| Tuesday, August 28 |
| » Defeated Yankees (56-63), 4-3 | Comiskey Park I (45-20) | 79-46 | Won 5 |
| » Starters: Ray Caldwell vs Lefty Williams | First | -- |
| Wednesday, August 29 |
| » Defeated Browns (49-77), 6-0 | Comiskey Park I (46-20) | 80-46 | Won 6 |
| » Starters: Ernie Koob vs Reb Russell | First | -- |
| » Defeated Browns (49-78), 11-1 | Comiskey Park I (47-20) | 81-46 | Won 7 |
| » Starters: Tom Rogers vs Joe Benz | First | -- |
| Thursday, August 30 |
| » Defeated Browns (49-79), 8-4 | Comiskey Park I (48-20) | 82-46 | Won 8 |
| » Starters: Bob Groom vs Eddie Cicotte | First | -- |
| Friday, August 31 |
| » Defeated Browns (49-80), 8-2 | Comiskey Park I (49-20) | 83-46 | Won 9 |
| » Starters: Dave Davenport vs Red Faber | First | -- |
| Saturday, September 1 |
| » Lost to Browns (50-80), 6-3 | Comiskey Park I (49-21) | 83-47 | |
| » Starters: Ernie Koob vs Dave Danforth | First | -- |
| Sunday, September 2 |
| » Defeated Tigers (65-62), 7-2 | Comiskey Park I (50-21) | 84-47 | |
| » Starters: Willie Mitchell vs Eddie Cicotte | First | -- |
| » Defeated Tigers (65-63), 6-5 | Comiskey Park I (51-21) | 85-47 | Won 2 |
| » Starters: George Cunningham vs Reb Russell | First | -- |
| Monday, September 3 |
| » Defeated Tigers (65-64), 7-5 | Comiskey Park I (52-21) | 86-47 | Won 3 |
| » Starters: Howard Ehmke vs Red Faber | First | -- |
| » Defeated Tigers (65-65), 14-8 | Comiskey Park I (53-21) | 87-47 | Won 4 |
| » Starters: Bernie Boland vs Red Faber | First | -- |
| Tuesday, September 4 |
| » Defeated Browns (50-84), 13-6 | Sportsman's Park III (6-4) | 88-47 | Won 5 |
| » Starters: Red Faber vs Ernie Koob | First | -- |
| Wednesday, September 5 |
| » Defeated Browns (50-85), 4-1 | Sportsman's Park III (7-4) | 89-47 | Won 6 |
| » Starters: Lefty Williams vs Allen Sothoron | First | -- |
| Saturday, September 8 |
| » Defeated Indians (73-61), 2-0 | Comiskey Park I (54-21) | 90-47 | Won 7 |
| » Starters: Jim Bagby vs Eddie Cicotte | First | -- |
| Sunday, September 9 |
| » Cleveland forfeited to Chicago. | Comiskey Park I (55-21) | 91-47 | Won 8 |
| » Starters: Stan Coveleski vs Reb Russell | First | -- |
| Friday, September 14 |
| » Defeated Tigers (68-70), 7-3 | Tiger Stadium (7-2) | 92-47 | Won 9 |
| » Starters: Eddie Cicotte vs Willie Mitchell | First | -- |
| Saturday, September 15 |
| » Lost to Tigers (69-70), 4-3 | Tiger Stadium (7-3) | 92-48 | |
| » Starters: Reb Russell vs Hooks Dauss | First | -- |
| » Defeated Tigers (69-71), 2-1 | Tiger Stadium (8-3) | 93-48 | |
| » Starters: Red Faber vs George Cunningham | First | -- |
| Sunday, September 16 |
| » Defeated Browns (52-90), 4-3 | Comiskey Park I (56-21) | 94-48 | Won 2 |
| » Starters: Dave Davenport vs Lefty Williams | First | -- |
| Monday, September 17 |
| Future White Sox Al Gettel is born in Norfolk, VA. |
| Tuesday, September 18 |
| » Defeated Athletics (49-89), 6-1 | Shibe Park (7-2) | 95-48 | Won 3 |
| » Starters: Red Faber vs Bullet Joe Bush | First | -- |
| Wednesday, September 19 |
| » Lost to Athletics (50-89), 2-1 | Shibe Park (7-3) | 95-49 | |
| » Starters: Eddie Cicotte vs Jing Johnson | First | -- |
| Thursday, September 20 |
| » Defeated Athletics (50-90), 5-3 | Shibe Park (8-3) | 96-49 | |
| » Starters: Lefty Williams vs Elmer Myers | First | -- |
| Friday, September 21 |
| » Defeated Red Sox (84-57), 2-1 | Fenway Park (5-4) | 97-49 | Won 2 |
| » Starters: Red Faber vs Dutch Leonard | First | -- |
| Future White Sox Joe Haynes is born in Lincolnton, GA. |
| Saturday, September 22 |
| » Lost to Red Sox (85-57), 4-1 | Fenway Park (5-5) | 97-50 | |
| » Starters: Joe Benz vs Carl Mays | First | -- |
| » Major-league debuts: Jimmy Cooney (Red Sox) |
| Monday, September 24 |
| » Lost to Red Sox (86-57), 3-0 | Fenway Park (5-6) | 97-51 | Lost 2 |
| » Starters: Reb Russell vs Babe Ruth | First | -- |
| Tuesday, September 25 |
| » Defeated Senators (68-75), 7-5 | Griffith Stadium (4-5) | 98-51 | |
| » Starters: Eddie Cicotte vs Harry Harper | First | -- |
| Wednesday, September 26 |
| » Lost to Senators (69-75), 5-4 | Griffith Stadium (4-6) | 98-52 | |
| » Starters: Red Faber vs George Dumont | First | -- |
| Future White Sox Thurman Tucker is born in Gordon, TX. |
| Thursday, September 27 |
| » Defeated Senators (69-76), 6-1 | Griffith Stadium (5-6) | 99-52 | |
| » Starters: Joe Benz vs Jim Shaw | First | -- |
| Saturday, September 29 |
| » Lost to Yankees (68-80), 12-8 | Polo Grounds V (3-6) | 99-53 | |
| » Starters: Lefty Williams vs Bob Shawkey | First | -- |
| » Defeated Yankees (68-81), 3-1 | Polo Grounds V (4-6) | 100-53 | |
| » Starters: Eddie Cicotte vs Hank Thormahlen | First | -- |
| » Major-league debuts: Hank Thormahlen (Yankees) |
| Monday, October 1 |
| » Lost to Yankees (69-81), 4-2 | Polo Grounds V (4-7) | 100-54 | |
| » Starters: Lefty Williams vs Urban Shocker | First | -- |
| Wednesday, October 17 |
| Future White Sox John Ostrowski is born in Chicago, IL. |
| Sunday, October 21 |
| Future White Sox Frank Papish is born in Pueblo, CO. |
Game information provided by Retrosheet (www.retrosheet.org) |
