| Tuesday, January 30 |
| Future Senator Mickey Harris is born in New York, NY. |
| Wednesday, January 31 |
| Former Senator Pete O'Brien dies in Jersey City, NJ at the age of 40. |
| Wednesday, April 11 |
| » Defeated Athletics (0-1), 3-0 | Shibe Park (1-0) | 1-0 | |
| » Starters: Walter Johnson vs Bullet Joe Bush | First | -- |
| Thursday, April 12 |
| » Defeated Athletics (0-2), 6-2 | Shibe Park (2-0) | 2-0 | Won 2 |
| » Starters: Bert Gallia vs Elmer Myers | First | -- |
| Friday, April 13 |
| » Major-league debuts: Jimmy Ring (Reds) |
| Saturday, April 14 |
| » Lost to Athletics (1-2), 16-4 | Shibe Park (2-1) | 2-1 | |
| » Starters: Jim Shaw vs Jing Johnson | First | -- |
| Sunday, April 15 |
| Future Senator Elmer Gedeon is born in Cleveland, OH. |
| Tuesday, April 17 |
| » Lost to Yankees (2-2), 2-1 | Polo Grounds V (0-1) | 2-2 | Lost 2 |
| » Starters: Walter Johnson vs Allen Russell | Fourth | 2 out |
| Wednesday, April 18 |
| » Lost to Yankees (3-2), 7-5 | Polo Grounds V (0-2) | 2-3 | Lost 3 |
| » Starters: Bert Gallia vs Urban Shocker | Fourth | 2½ out |
| Thursday, April 19 |
| » Lost to Yankees (4-2), 3-2 | Polo Grounds V (0-3) | 2-4 | Lost 4 |
| » Starters: George Dumont vs Ray Caldwell | Fourth | 2½ out |
| Friday, April 20 |
| » Lost to Athletics (3-5), 6-4 | Griffith Stadium (0-1) | 2-5 | Lost 5 |
| » Starters: Jing Johnson vs Bert Gallia | Sixth | 3½ out |
| Saturday, April 21 |
| » Defeated Athletics (3-6), 11-6 | Griffith Stadium (1-1) | 3-5 | |
| » Starters: Walt Johnson vs Walter Johnson | Fifth | 3½ out |
| Monday, April 23 |
| » Lost to Athletics (4-6), 4-3 | Griffith Stadium (1-2) | 3-6 | |
| » Starters: Bullet Joe Bush vs George Dumont | Sixth | 4½ out |
| Tuesday, April 24 |
| » Defeated Athletics (4-7), 8-5 | Griffith Stadium (2-2) | 4-6 | |
| » Starters: Elmer Myers vs Jim Shaw | Fifth | 4½ out |
| Wednesday, April 25 |
| » Lost to Red Sox (7-4), 5-4 | Fenway Park (0-1) | 4-7 | |
| » Starters: Doc Ayers vs Babe Ruth | Seventh | 4½ out |
| Saturday, April 28 |
| » Lost to Red Sox (8-4), 7-1 | Fenway Park (0-2) | 4-8 | Lost 2 |
| » Starters: Walter Johnson vs Ernie Shore | Sixth | 4½ out |
| Monday, April 30 |
| » Lost to Yankees (7-5), 4-3 | Griffith Stadium (2-3) | 4-9 | Lost 3 |
| » Starters: Urban Shocker vs George Dumont | Eighth | 5 out |
| Tuesday, May 1 |
| » Defeated Yankees (7-6), 3-2 | Griffith Stadium (3-3) | 5-9 | |
| » Starters: Bob Shawkey vs Harry Harper | Seventh | 4½ out |
| Wednesday, May 2 |
| » Lost to Yankees (8-6), 2-0 | Griffith Stadium (3-4) | 5-10 | |
| » Starters: Ray Fisher vs Walter Johnson | Eighth | 5 out |
| Thursday, May 3 |
| » Defeated Yankees (8-7), 3-1 | Griffith Stadium (4-4) | 6-10 | |
| » Starters: Ray Caldwell vs Jim Shaw | Seventh | 5 out |
| Sunday, May 6 |
| Future Senator Mike McCormick is born in Angels Camp, CA. |
| Monday, May 7 |
| » Lost to Red Sox (11-4), 1-0 | Griffith Stadium (4-5) | 6-11 | |
| » Starters: Babe Ruth vs Walter Johnson | Seventh | 6 out |
| Wednesday, May 9 |
| » Lost to Red Sox (12-4), 4-1 | Griffith Stadium (4-6) | 6-12 | Lost 2 |
| » Starters: Ernie Shore vs George Dumont | Seventh | 6 out |
| » Defeated Red Sox (12-5), 4-3 | Griffith Stadium (5-6) | 7-12 | |
| » Starters: Carl Mays vs Jim Shaw | Seventh | 6 out |
| Thursday, May 10 |
| » Lost to Indians (12-12), 4-3 | League Park II (0-1) | 7-13 | |
| » Starters: Harry Harper vs Fritz Coumbe | Seventh | 7 out |
| Friday, May 11 |
| » Lost to Indians (13-12), 4-3 | League Park II (0-2) | 7-14 | Lost 2 |
| » Starters: Walter Johnson vs Guy Morton | Eighth | 8 out |
| Saturday, May 12 |
| » Defeated Indians (13-13), 4-1 | League Park II (1-2) | 8-14 | |
| » Starters: Bert Gallia vs Jim Bagby | Sixth | 8 out |
| Sunday, May 13 |
| » Lost to Indians (14-13), 2-0 | League Park II (1-3) | 8-15 | |
| » Starters: Jim Shaw vs Stan Coveleski | Seventh | 8 out |
| Monday, May 14 |
| » Lost to Tigers (10-14), 3-2 | Tiger Stadium (0-1) | 8-16 | Lost 2 |
| » Starters: George Dumont vs Bernie Boland | Seventh | 8 out |
| Tuesday, May 15 |
| » Defeated Tigers (10-15), 11-5 | Tiger Stadium (1-1) | 9-16 | |
| » Starters: Walter Johnson vs Harry Coveleski | Seventh | 8 out |
| Wednesday, May 16 |
| » Defeated Tigers (10-16), 5-1 | Tiger Stadium (2-1) | 10-16 | Won 2 |
| » Starters: Bert Gallia vs Willie Mitchell | Sixth | 8 out |
| Thursday, May 17 |
| » Defeated Tigers (10-17), 4-2 | Tiger Stadium (3-1) | 11-16 | Won 3 |
| » Starters: Jim Shaw vs Howard Ehmke | Sixth | 7 out |
| Friday, May 18 |
| » Defeated Browns (14-17), 8-2 | Sportsman's Park III (1-0) | 12-16 | Won 4 |
| » Starters: Harry Harper vs Eddie Plank | Fifth | 6 out |
| Saturday, May 19 |
| » Defeated Browns (14-18), 9-6 | Sportsman's Park III (2-0) | 13-16 | Won 5 |
| » Starters: Walter Johnson vs Dave Davenport | Fifth | 5½ out |
| Sunday, May 20 |
| » Lost to Browns (15-18), 4-3 | Sportsman's Park III (2-1) | 13-17 | |
| » Starters: Bert Gallia vs Bob Groom | Sixth | 6 out |
| Wednesday, May 23 |
| » Lost to White Sox (23-13), 2-1 | Comiskey Park I (0-1) | 13-18 | Lost 2 |
| » Starters: Jim Shaw vs Eddie Cicotte | Sixth | 7 out |
| Thursday, May 24 |
| » Lost to White Sox (24-13), 1-0 | Comiskey Park I (0-2) | 13-19 | Lost 3 |
| » Starters: George Dumont vs Reb Russell | Sixth | 8 out |
| Friday, May 25 |
| » Lost to White Sox (25-13), 5-1 | Comiskey Park I (0-3) | 13-20 | Lost 4 |
| » Starters: Harry Harper vs Joe Benz | Sixth | 9 out |
| Saturday, May 26 |
| » Tied White Sox, 1-1 | Comiskey Park I (0-3) | 13-20 | |
| » Starters: Bert Gallia vs Jim Scott | Sixth | 9½ out |
| Sunday, May 27 |
| » Lost to White Sox (26-13), 4-1 | Comiskey Park I (0-4) | 13-21 | Lost 5 |
| » Starters: Walter Johnson vs Eddie Cicotte | Sixth | 10 out |
| Tuesday, May 29 |
| » Lost to Red Sox (23-10), 2-1 | Griffith Stadium (5-7) | 13-22 | Lost 6 |
| » Starters: Dutch Leonard vs George Dumont | Eighth | 12 out |
| » Lost to Red Sox (24-10), 9-0 | Griffith Stadium (5-8) | 13-23 | Lost 7 |
| » Starters: Babe Ruth vs Harry Harper | Eighth | 12 out |
| Wednesday, May 30 |
| » Lost to Red Sox (25-10), 4-3 | Griffith Stadium (5-9) | 13-24 | Lost 8 |
| » Starters: Ernie Shore vs Bert Gallia | Eighth | 14 out |
| » Lost to Red Sox (26-10), 3-2 | Griffith Stadium (5-10) | 13-25 | Lost 9 |
| » Starters: King Bader vs Jim Shaw | Eighth | 14 out |
| Friday, June 1 |
| » Lost to Browns (16-23), 4-2 | Griffith Stadium (5-11) | 13-26 | Lost 10 |
| » Starters: Eddie Plank vs Walter Johnson | Eighth | 14½ out |
| Saturday, June 2 |
| » Defeated Browns (16-24), 2-0 | Griffith Stadium (6-11) | 14-26 | |
| » Starters: Allen Sothoron vs George Dumont | Eighth | 13½ out |
| Monday, June 4 |
| » Defeated Browns (16-25), 7-4 | Griffith Stadium (7-11) | 15-26 | Won 2 |
| » Starters: Dave Davenport vs Jim Shaw | Seventh | 13½ out |
| Tuesday, June 5 |
| » Lost to Browns (17-25), 6-2 | Griffith Stadium (7-12) | 15-27 | |
| » Starters: Bob Groom vs Bert Gallia | Seventh | 14½ out |
| Wednesday, June 6 |
| » Defeated White Sox (30-14), 3-0 | Griffith Stadium (8-12) | 16-27 | |
| » Starters: Eddie Cicotte vs George Dumont | Seventh | 13½ out |
| Thursday, June 7 |
| » Defeated White Sox (30-15), 1-0 | Griffith Stadium (9-12) | 17-27 | Won 2 |
| » Starters: Reb Russell vs Walter Johnson | Seventh | 13 out |
| Friday, June 8 |
| » Lost to White Sox (31-15), 11-4 | Griffith Stadium (9-13) | 17-28 | |
| » Starters: Joe Benz vs Jim Shaw | Seventh | 13½ out |
| Saturday, June 9 |
| » Lost to White Sox (32-15), 5-4 | Griffith Stadium (9-14) | 17-29 | Lost 2 |
| » Starters: Jim Scott vs Harry Harper | Seventh | 14½ out |
| Tuesday, June 12 |
| » Tied Indians, 2-2 | Griffith Stadium (9-14) | 17-29 | |
| » Starters: Guy Morton vs George Dumont | Seventh | 14½ out |
| Wednesday, June 13 |
| » Defeated Indians (26-26), 7-5 | Griffith Stadium (10-14) | 18-29 | |
| » Starters: Stan Coveleski vs Bert Gallia | Seventh | 13½ out |
| » Tied Indians, 1-1 | Griffith Stadium (10-14) | 18-29 | |
| » Starters: Otis Lambeth vs Harry Harper | Seventh | 13½ out |
| Friday, June 15 |
| » Lost to Tigers (22-25), 4-3 | Griffith Stadium (10-15) | 18-30 | |
| » Starters: Bill James vs Walter Johnson | Eighth | 14½ out |
| Saturday, June 16 |
| » Lost to Tigers (23-25), 3-2 | Griffith Stadium (10-16) | 18-31 | Lost 2 |
| » Starters: Howard Ehmke vs George Dumont | Seventh | 15½ out |
| Monday, June 18 |
| » Lost to Tigers (24-25), 1-0 | Griffith Stadium (10-17) | 18-32 | Lost 3 |
| » Starters: Hooks Dauss vs Harry Harper | Eighth | 15 out |
| Future Senator Jimmy Pofahl is born in Faribault, MN. |
| Tuesday, June 19 |
| » Defeated Tigers (24-26), 3-0 | Griffith Stadium (11-17) | 19-32 | |
| » Starters: Bill James vs Walter Johnson | Eighth | 14½ out |
| Wednesday, June 20 |
| » Defeated Athletics (18-31), 5-3 | Griffith Stadium (12-17) | 20-32 | Won 2 |
| » Starters: Rube Schauer vs Jim Shaw | Seventh | 14½ out |
| Thursday, June 21 |
| » Lost to Athletics (19-31), 3-0 | Griffith Stadium (12-18) | 20-33 | |
| » Starters: Bullet Joe Bush vs George Dumont | Eighth | 14½ out |
| Friday, June 22 |
| » Defeated Athletics (19-32), 6-5 | Griffith Stadium (13-18) | 21-33 | |
| » Starters: Socks Seibold vs Harry Harper | Seventh | 14½ out |
| Saturday, June 23 |
| » Lost to Red Sox (35-21), 4-0 | Fenway Park (0-3) | 21-34 | |
| » Starters: Doc Ayers vs Babe Ruth | Seventh | 16 out |
| » Lost to Red Sox (36-21), 5-0 | Fenway Park (0-4) | 21-35 | Lost 2 |
| » Starters: Walter Johnson vs Dutch Leonard | Seventh | 16 out |
| Future Senator Jack Sanford is born in Chatham, VA. |
| Monday, June 25 |
| » Defeated Red Sox (36-22), 4-0 | Fenway Park (1-4) | 22-35 | |
| » Starters: Harry Harper vs Rube Foster | Seventh | 16½ out |
| » Lost to Red Sox (37-22), 4-3 | Fenway Park (1-5) | 22-36 | |
| » Starters: George Dumont vs Herb Pennock | Seventh | 16½ out |
| Tuesday, June 26 |
| » Defeated Red Sox (37-23), 3-2 | Fenway Park (2-5) | 23-36 | |
| » Starters: Jim Shaw vs Carl Mays | Sixth | 16 out |
| Wednesday, June 27 |
| » Defeated Red Sox (37-24), 7-6 | Fenway Park (3-5) | 24-36 | Won 2 |
| » Starters: Bert Gallia vs Ernie Shore | Sixth | 16½ out |
| Thursday, June 28 |
| » Defeated Athletics (20-38), 4-3 | Shibe Park (3-1) | 25-36 | Won 3 |
| » Starters: Walter Johnson vs Jing Johnson | Sixth | 15½ out |
| Friday, June 29 |
| » Lost to Athletics (21-38), 4-3 | Shibe Park (3-2) | 25-37 | |
| » Starters: Harry Harper vs Cy Falkenberg | Sixth | 16½ out |
| Saturday, June 30 |
| » Lost to Athletics (22-38), 14-6 | Shibe Park (3-3) | 25-38 | Lost 2 |
| » Starters: George Dumont vs Socks Seibold | Sixth | 17 out |
| » Lost to Athletics (23-38), 8-5 | Shibe Park (3-4) | 25-39 | Lost 3 |
| » Starters: Jim Shaw vs Bullet Joe Bush | Sixth | 17 out |
| Monday, July 2 |
| » Defeated Athletics (23-39), 6-0 | Shibe Park (4-4) | 26-39 | |
| » Starters: Bert Gallia vs Rube Schauer | Sixth | 16½ out |
| Wednesday, July 4 |
| » Defeated Yankees (35-30), 6-4 | Polo Grounds V (1-3) | 27-39 | Won 2 |
| » Starters: Harry Harper vs Bob Shawkey | Sixth | 17 out |
| » Defeated Yankees (35-31), 5-4 | Polo Grounds V (2-3) | 28-39 | Won 3 |
| » Starters: George Dumont vs Nick Cullop | Sixth | 17 out |
| Thursday, July 5 |
| » Defeated Yankees (35-32), 2-1 | Polo Grounds V (3-3) | 29-39 | Won 4 |
| » Starters: Jim Shaw vs Ray Fisher | Sixth | 16½ out |
| » Lost to Yankees (36-32), 5-4 | Polo Grounds V (3-4) | 29-40 | |
| » Starters: Bert Gallia vs Slim Love | Sixth | 16½ out |
| Sunday, July 8 |
| » Defeated Tigers (36-36), 10-5 | Tiger Stadium (4-1) | 30-40 | |
| » Starters: Walter Johnson vs Bernie Boland | Sixth | 15½ out |
| Monday, July 9 |
| » Defeated Tigers (36-37), 8-1 | Tiger Stadium (5-1) | 31-40 | Won 2 |
| » Starters: Harry Harper vs Deacon Jones | Sixth | 15 out |
| » Lost to Tigers (37-37), 10-2 | Tiger Stadium (5-2) | 31-41 | |
| » Starters: Jim Shaw vs Bill James | Sixth | 15 out |
| Tuesday, July 10 |
| » Lost to Tigers (38-37), 5-4 | Tiger Stadium (5-3) | 31-42 | Lost 2 |
| » Starters: George Dumont vs Bernie Boland | Sixth | 15 out |
| Wednesday, July 11 |
| » Lost to Indians (43-37), 3-0 | League Park II (1-4) | 31-43 | Lost 3 |
| » Starters: Bert Gallia vs Stan Coveleski | Sixth | 15½ out |
| Thursday, July 12 |
| » Lost to Indians (44-37), 7-0 | League Park II (1-5) | 31-44 | Lost 4 |
| » Starters: Walter Johnson vs Jim Bagby | Sixth | 17 out |
| Saturday, July 14 |
| » Lost to Indians (45-37), 7-5 | League Park II (1-6) | 31-45 | Lost 5 |
| » Starters: Bert Gallia vs Guy Morton | Sixth | 17 out |
| » Defeated Indians (45-38), 3-0 | League Park II (2-6) | 32-45 | |
| » Starters: Harry Harper vs Fritz Coumbe | Sixth | 17 out |
| Sunday, July 15 |
| » Defeated White Sox (51-31), 6-5 | Comiskey Park I (1-4) | 33-45 | Won 2 |
| » Starters: Jim Shaw vs Lefty Williams | Sixth | 16 out |
| Tuesday, July 17 |
| » Lost to White Sox (52-31), 5-0 | Comiskey Park I (1-5) | 33-46 | |
| » Starters: George Dumont vs Eddie Cicotte | Sixth | 18 out |
| » Lost to White Sox (53-31), 3-2 | Comiskey Park I (1-6) | 33-47 | Lost 2 |
| » Starters: Walter Johnson vs Red Faber | Sixth | 18 out |
| Wednesday, July 18 |
| » Lost to White Sox (54-31), 4-0 | Comiskey Park I (1-7) | 33-48 | Lost 3 |
| » Starters: Harry Harper vs Joe Benz | Sixth | 20 out |
| » Lost to White Sox (55-31), 7-4 | Comiskey Park I (1-8) | 33-49 | Lost 4 |
| » Starters: Bert Gallia vs Dave Danforth | Sixth | 20 out |
| Thursday, July 19 |
| » Lost to Browns (34-53), 4-2 | Sportsman's Park III (2-2) | 33-50 | Lost 5 |
| » Starters: Walter Johnson vs Allen Sothoron | Sixth | 20 out |
| Friday, July 20 |
| » Lost to Browns (35-53), 5-2 | Sportsman's Park III (2-3) | 33-51 | Lost 6 |
| » Starters: Bert Gallia vs Dave Davenport | Eighth | 21 out |
| Saturday, July 21 |
| » Defeated Browns (35-54), 5-0 | Sportsman's Park III (3-3) | 34-51 | |
| » Starters: Harry Harper vs Tom Rogers | Sixth | 20½ out |
| Sunday, July 22 |
| » Lost to Browns (36-54), 4-0 | Sportsman's Park III (3-4) | 34-52 | |
| » Starters: Jim Shaw vs Eddie Plank | Sixth | 21 out |
| » Defeated Browns (36-55), 5-0 | Sportsman's Park III (4-4) | 35-52 | |
| » Starters: Doc Ayers vs Allen Sothoron | Sixth | 21 out |
| Monday, July 23 |
| Future Senator Ray Scarborough is born in Mount Gilead, NC. |
| Tuesday, July 24 |
| » Defeated Indians (49-43), 2-1 | Griffith Stadium (14-18) | 36-52 | Won 2 |
| » Starters: Stan Coveleski vs Walter Johnson | Sixth | 21 out |
| Thursday, July 26 |
| » Defeated Indians (49-44), 2-1 | Griffith Stadium (15-18) | 37-52 | Won 3 |
| » Starters: Jim Bagby vs George Dumont | Sixth | 21½ out |
| » Lost to Indians (50-44), 5-2 | Griffith Stadium (15-19) | 37-53 | |
| » Starters: Ed Klepfer vs Harry Harper | Sixth | 21½ out |
| Future Senator Jimmy Bloodworth is born in Tallahassee, FL. |
| Friday, July 27 |
| » Lost to Indians (51-44), 3-2 | Griffith Stadium (15-20) | 37-54 | Lost 2 |
| » Starters: Joe Boehling vs Bert Gallia | Sixth | 22 out |
| » Defeated Indians (51-45), 5-2 | Griffith Stadium (16-20) | 38-54 | |
| » Starters: Guy Morton vs Jim Shaw | Sixth | 22 out |
| Saturday, July 28 |
| » Defeated Indians (51-46), 5-4 | Griffith Stadium (17-20) | 39-54 | Won 2 |
| » Starters: Stan Coveleski vs Doc Ayers | Sixth | 20½ out |
| Sunday, July 29 |
| » Defeated Indians (51-47), 9-5 | League Park II (3-6) | 40-54 | Won 3 |
| » Starters: Walter Johnson vs Otis Lambeth | Sixth | 20 out |
| Monday, July 30 |
| » Lost to Tigers (51-45), 16-4 | Griffith Stadium (17-21) | 40-55 | |
| » Starters: Harry Coveleski vs Harry Harper | Sixth | 20 out |
| Tuesday, July 31 |
| » Lost to Tigers (52-45), 8-4 | Griffith Stadium (17-22) | 40-56 | Lost 2 |
| » Starters: Hooks Dauss vs Doc Ayers | Sixth | 20 out |
| Wednesday, August 1 |
| » Defeated Tigers (52-46), 5-4 | Griffith Stadium (18-22) | 41-56 | |
| » Starters: Bill James vs George Dumont | Sixth | 20 out |
| Thursday, August 2 |
| » Defeated Tigers (52-47), 4-2 | Griffith Stadium (19-22) | 42-56 | Won 2 |
| » Starters: Howard Ehmke vs Bert Gallia | Sixth | 20 out |
| Friday, August 3 |
| » Lost to Browns (38-63), 5-4 | Griffith Stadium (19-23) | 42-57 | |
| » Starters: Allen Sothoron vs Harry Harper | Sixth | 21 out |
| Future Senator Milo Candini is born in Manteca, CA. |
| Saturday, August 4 |
| » Defeated Browns (38-64), 5-3 | Griffith Stadium (20-23) | 43-57 | |
| » Starters: Dave Davenport vs Doc Ayers | Sixth | 21½ out |
| Monday, August 6 |
| » Defeated Browns (38-65), 1-0 | Griffith Stadium (21-23) | 44-57 | Won 2 |
| » Starters: Eddie Plank vs Walter Johnson | Sixth | 20½ out |
| Tuesday, August 7 |
| » Defeated Browns (38-66), 3-2 | Griffith Stadium (22-23) | 45-57 | Won 3 |
| » Starters: Bob Groom vs Jim Shaw | Sixth | 19½ out |
| Wednesday, August 8 |
| » Defeated White Sox (66-40), 2-0 | Griffith Stadium (23-23) | 46-57 | Won 4 |
| » Starters: Eddie Cicotte vs Harry Harper | Sixth | 18½ out |
| Thursday, August 9 |
| » Lost to White Sox (67-40), 3-2 | Griffith Stadium (23-24) | 46-58 | |
| » Starters: Joe Benz vs Bert Gallia | Sixth | 19½ out |
| Friday, August 10 |
| » Defeated White Sox (67-41), 4-0 | Griffith Stadium (24-24) | 47-58 | |
| » Starters: Red Faber vs Walter Johnson | Sixth | 18½ out |
| Saturday, August 11 |
| » Defeated White Sox (67-42), 3-2 | Griffith Stadium (25-24) | 48-58 | Won 2 |
| » Starters: Eddie Cicotte vs Jim Shaw | Sixth | 17½ out |
| Monday, August 13 |
| » Defeated Yankees (53-53), 9-5 | Griffith Stadium (26-24) | 49-58 | Won 3 |
| » Starters: Ray Fisher vs Harry Harper | Sixth | 17½ out |
| Tuesday, August 14 |
| » Defeated Yankees (53-54), 1-0 | Griffith Stadium (27-24) | 50-58 | Won 4 |
| » Starters: George Mogridge vs Jim Shaw | Sixth | 16½ out |
| » Defeated Yankees (53-55), 10-1 | Griffith Stadium (28-24) | 51-58 | Won 5 |
| » Starters: Nick Cullop vs Walter Johnson | Sixth | 16½ out |
| » Major-league debuts: Aaron Ward (Yankees) |
| Friday, August 17 |
| » Defeated Tigers (58-55), 9-6 | Tiger Stadium (6-3) | 52-58 | Won 6 |
| » Starters: Harry Harper vs Hooks Dauss | Sixth | 15½ out |
| Saturday, August 18 |
| » Defeated Tigers (58-56), 5-2 | Tiger Stadium (7-3) | 53-58 | Won 7 |
| » Starters: Walter Johnson vs George Cunningham | Sixth | 16 out |
| Monday, August 20 |
| » Lost to Browns (45-72), 4-1 | Sportsman's Park III (4-5) | 53-59 | |
| » Starters: Jim Shaw vs Ernie Koob | Sixth | 17 out |
| Wednesday, August 22 |
| » Defeated Browns (45-73), 2-1 | Sportsman's Park III (5-5) | 54-59 | |
| » Starters: Harry Harper vs Bob Groom | Sixth | 17 out |
| » Lost to Browns (46-73), 9-4 | Sportsman's Park III (5-6) | 54-60 | |
| » Starters: George Dumont vs Dave Davenport | Sixth | 17 out |
| Thursday, August 23 |
| » Lost to White Sox (75-46), 6-0 | Comiskey Park I (1-9) | 54-61 | Lost 2 |
| » Starters: Jim Shaw vs Eddie Cicotte | Sixth | 18 out |
| Saturday, August 25 |
| » Lost to White Sox (76-46), 4-1 | Comiskey Park I (1-10) | 54-62 | Lost 3 |
| » Starters: Walter Johnson vs Red Faber | Sixth | 19 out |
| Sunday, August 26 |
| » Lost to Indians (68-57), 2-1 | League Park II (3-7) | 54-63 | Lost 4 |
| » Starters: Doc Ayers vs Jim Bagby | Sixth | 20 out |
| Monday, August 27 |
| » Defeated Indians (68-58), 11-9 | League Park II (4-7) | 55-63 | |
| » Starters: Harry Harper vs Ed Klepfer | Sixth | 20 out |
| Friday, August 31 |
| » Defeated Yankees (56-64), 4-1 | Polo Grounds V (4-4) | 56-63 | Won 2 |
| » Starters: Doc Ayers vs George Mogridge | Fifth | 21½ out |
| » Defeated Yankees (56-65), 6-3 | Polo Grounds V (5-4) | 57-63 | Won 3 |
| » Starters: Jim Shaw vs Urban Shocker | Fifth | 21½ out |
| Monday, September 3 |
| » Lost to Athletics (45-78), 7-4 | Shibe Park (4-5) | 57-64 | |
| » Starters: Bert Gallia vs Bullet Joe Bush | Sixth | 24 out |
| » Lost to Athletics (46-78), 9-2 | Shibe Park (4-6) | 57-65 | Lost 2 |
| » Starters: Walter Johnson vs Jing Johnson | Sixth | 24 out |
| Tuesday, September 4 |
| » Lost to Athletics (47-78), 2-1 | Shibe Park (4-7) | 57-66 | Lost 3 |
| » Starters: Harry Harper vs Bullet Joe Bush | Sixth | 25 out |
| Wednesday, September 5 |
| » Defeated Yankees (59-67), 3-0 | Griffith Stadium (29-24) | 58-66 | |
| » Starters: Urban Shocker vs Doc Ayers | Fifth | 25 out |
| Friday, September 7 |
| » Defeated Yankees (59-68), 6-0 | Griffith Stadium (30-24) | 59-66 | Won 2 |
| » Starters: Slim Love vs Walter Johnson | Sixth | 25 out |
| » Lost to Yankees (60-68), 4-1 | Griffith Stadium (30-25) | 59-67 | |
| » Starters: Bob Shawkey vs Jim Shaw | Sixth | 25 out |
| Saturday, September 8 |
| » Lost to Yankees (61-68), 2-0 | Griffith Stadium (30-26) | 59-68 | Lost 2 |
| » Starters: Ray Caldwell vs George Dumont | Fifth | 25½ out |
| » Defeated Yankees (61-69), 3-0 | Griffith Stadium (31-26) | 60-68 | |
| » Starters: Nick Cullop vs Doc Ayers | Fifth | 25½ out |
| Monday, September 10 |
| » Defeated Red Sox (80-51), 2-1 | Griffith Stadium (32-26) | 61-68 | Won 2 |
| » Starters: Babe Ruth vs Harry Harper | Sixth | 25½ out |
| » Lost to Red Sox (81-51), 4-3 | Griffith Stadium (32-27) | 61-69 | |
| » Starters: Carl Mays vs Jim Shaw | Sixth | 25½ out |
| Tuesday, September 11 |
| » Defeated Red Sox (81-52), 4-3 | Griffith Stadium (33-27) | 62-69 | |
| » Starters: Dutch Leonard vs Walter Johnson | Sixth | 25 out |
| Wednesday, September 12 |
| » Tied Red Sox, 1-1 | Griffith Stadium (33-27) | 62-69 | |
| » Starters: Ernie Shore vs Doc Ayers | Sixth | 25 out |
| Thursday, September 13 |
| » Defeated Athletics (48-86), 2-1 | Griffith Stadium (34-27) | 63-69 | Won 2 |
| » Starters: Elmer Myers vs Bert Gallia | Sixth | 24½ out |
| Friday, September 14 |
| » Lost to Athletics (49-86), 2-1 | Griffith Stadium (34-28) | 63-70 | |
| » Starters: Rollie Naylor vs Jim Shaw | Sixth | 25½ out |
| Saturday, September 15 |
| » Defeated Athletics (49-87), 5-0 | Griffith Stadium (35-28) | 64-70 | |
| » Starters: Win Noyes vs Harry Harper | Fifth | 24½ out |
| » Defeated Athletics (49-88), 4-0 | Griffith Stadium (36-28) | 65-70 | Won 2 |
| » Starters: Rube Schauer vs Walter Johnson | Fifth | 24½ out |
| Monday, September 17 |
| Future Senator Al Gettel is born in Norfolk, VA. |
| Tuesday, September 18 |
| » Defeated Browns (52-91), 9-3 | Griffith Stadium (37-28) | 66-70 | Won 3 |
| » Starters: Ernie Koob vs Doc Ayers | Fifth | 25 out |
| Wednesday, September 19 |
| » Defeated Browns (52-92), 6-4 | Griffith Stadium (38-28) | 67-70 | Won 4 |
| » Starters: Bob Groom vs Walter Johnson | Fifth | 24 out |
| Thursday, September 20 |
| » Lost to Browns (53-92), 4-2 | Griffith Stadium (38-29) | 67-71 | |
| » Starters: Dave Davenport vs Bert Gallia | Fifth | 25 out |
| Friday, September 21 |
| » Lost to Tigers (73-72), 7-1 | Griffith Stadium (38-30) | 67-72 | Lost 2 |
| » Starters: Bernie Boland vs Harry Harper | Fifth | 26 out |
| Future Senator Joe Haynes is born in Lincolnton, GA. |
| Saturday, September 22 |
| » Lost to Tigers (74-72), 4-0 | Griffith Stadium (38-31) | 67-73 | Lost 3 |
| » Starters: Howard Ehmke vs Walter Johnson | Fifth | 26 out |
| Monday, September 24 |
| » Lost to Tigers (75-72), 8-3 | Griffith Stadium (38-32) | 67-74 | Lost 4 |
| » Starters: Bill James vs Doc Ayers | Fifth | 25½ out |
| » Defeated Tigers (75-73), 2-0 | Griffith Stadium (39-32) | 68-74 | |
| » Starters: Hooks Dauss vs Jim Shaw | Fifth | 25½ out |
| Tuesday, September 25 |
| » Lost to White Sox (97-51), 7-5 | Griffith Stadium (39-33) | 68-75 | |
| » Starters: Eddie Cicotte vs Harry Harper | Fifth | 26½ out |
| Wednesday, September 26 |
| » Defeated White Sox (97-52), 5-4 | Griffith Stadium (40-33) | 69-75 | |
| » Starters: Red Faber vs George Dumont | Fifth | 25½ out |
| Thursday, September 27 |
| » Lost to White Sox (98-52), 6-1 | Griffith Stadium (40-34) | 69-76 | |
| » Starters: Joe Benz vs Jim Shaw | Fifth | 26½ out |
| Friday, September 28 |
| » Lost to Indians (87-63), 3-1 | Griffith Stadium (40-35) | 69-77 | Lost 2 |
| » Starters: Guy Morton vs Doc Ayers | Fifth | 27 out |
| Saturday, September 29 |
| » Defeated Indians (87-64), 11-2 | Griffith Stadium (41-35) | 70-77 | |
| » Starters: Red Torkelson vs Harry Harper | Fifth | 26 out |
| » Defeated Indians (87-65), 4-3 | Griffith Stadium (42-35) | 71-77 | Won 2 |
| » Starters: Fritz Coumbe vs Jim Shaw | Fifth | 26 out |
| Sunday, September 30 |
| » Lost to Indians (88-65), 2-1 | League Park II (4-8) | 71-78 | |
| » Starters: George Dumont vs Jim Bagby | Fifth | 26½ out |
| Tuesday, October 2 |
| » Defeated Red Sox (89-60), 9-7 | Fenway Park (4-5) | 72-78 | |
| » Starters: Harry Harper vs Dutch Leonard | Fifth | 26 out |
| » Lost to Red Sox (90-60), 2-1 | Fenway Park (4-6) | 72-79 | |
| » Starters: Doc Ayers vs Carl Mays | Fifth | 26 out |
| Wednesday, October 3 |
| » Defeated Red Sox (90-61), 6-0 | Fenway Park (5-6) | 73-79 | |
| » Starters: Walter Johnson vs Babe Ruth | Fifth | 25½ out |
| Thursday, October 4 |
| » Defeated Red Sox (90-62), 5-4 | Fenway Park (6-6) | 74-79 | Won 2 |
| » Starters: Jim Shaw vs Herb Pennock | Fifth | 25 out |
| Saturday, October 6 |
| Future Senator Paul Calvert is born in Montreal, PQ. |
| Monday, October 8 |
| Future Senator Hal Toenes is born in Mobile, AL. |
| Wednesday, October 17 |
| Future Senator John Ostrowski is born in Chicago, IL. |
| Tuesday, November 20 |
| Future Senator Felix Mackiewicz is born in Chicago, IL. |
| Wednesday, December 12 |
| Future Senator Clyde Kluttz is born in Rockwell, NC. |
Game information provided by Retrosheet (www.retrosheet.org) |
