| Thursday, January 6 |
| Future White Sox Phil Masi is born in Chicago, IL. |
| Thursday, February 10 |
| Future White Sox Ralph Hodgin is born in Greensboro, NC. |
| Saturday, March 18 |
| Future White Sox Hi Bithorn is born in Santurce, P.R. |
| Wednesday, April 12 |
| » Lost to Tigers (1-0), 4-0 | Comiskey Park I (0-1) | 0-1 | |
| » Starters: Harry Coveleski vs Reb Russell | Second | 1 out |
| » Major-league debuts: Zeb Terry (White Sox) |
| Thursday, April 13 |
| » Defeated Tigers (1-1), 8-6 | Comiskey Park I (1-1) | 1-1 | |
| » Starters: Hooks Dauss vs Dave Danforth | Third | 1 out |
| Friday, April 14 |
| » Defeated Tigers (1-2), 7-2 | Comiskey Park I (2-1) | 2-1 | Won 2 |
| » Starters: George Cunningham vs Red Faber | Third | ½ out |
| » Major-league debuts: George Cunningham (Tigers) |
| Saturday, April 15 |
| » Defeated Tigers (1-3), 9-4 | Comiskey Park I (3-1) | 3-1 | Won 3 |
| » Starters: Bernie Boland vs Eddie Cicotte | Second | ½ out |
| » Major-league debuts: George Harper (Tigers) |
| Sunday, April 16 |
| » Lost to Browns (3-1), 6-5 | Comiskey Park I (3-2) | 3-2 | |
| » Starters: Carl Weilman vs Joe Benz | Third | 1 out |
| Monday, April 17 |
| » Defeated Browns (3-2), 6-5 | Comiskey Park I (4-2) | 4-2 | |
| » Starters: Dave Davenport vs Dave Danforth | Second | 1 out |
| Tuesday, April 18 |
| » Defeated Browns (3-3), 7-2 | Comiskey Park I (5-2) | 5-2 | Won 2 |
| » Starters: Bob Groom vs Red Faber | Second | 1 out |
| Wednesday, April 19 |
| » Lost to Browns (4-3), 6-2 | Comiskey Park I (5-3) | 5-3 | |
| » Starters: Carl Weilman vs Eddie Cicotte | Third | 2 out |
| Thursday, April 20 |
| » Lost to Tigers (4-4), 2-1 | Tiger Stadium (0-1) | 5-4 | Lost 2 |
| » Starters: Mellie Wolfgang vs Harry Coveleski | Fourth | 1½ out |
| Friday, April 21 |
| » Lost to Tigers (5-4), 3-2 | Tiger Stadium (0-2) | 5-5 | Lost 3 |
| » Starters: Dave Danforth vs Hooks Dauss | Sixth | 1½ out |
| Sunday, April 23 |
| » Defeated Tigers (5-5), 3-2 | Tiger Stadium (1-2) | 6-5 | |
| » Starters: Red Faber vs Bill James | Fourth | 2 out |
| Monday, April 24 |
| » Lost to Tigers (6-5), 4-2 | Tiger Stadium (1-3) | 6-6 | |
| » Starters: Jim Scott vs Harry Coveleski | Fifth | 1½ out |
| Tuesday, April 25 |
| » Lost to Indians (5-5), 9-2 | League Park II (0-1) | 6-7 | Lost 2 |
| » Starters: Eddie Cicotte vs Fritz Coumbe | Fifth | 2½ out |
| Wednesday, April 26 |
| » Lost to Indians (6-5), 5-3 | League Park II (0-2) | 6-8 | Lost 3 |
| » Starters: Jim Scott vs Stan Coveleski | Sixth | 2½ out |
| Thursday, April 27 |
| » Defeated Indians (6-6), 5-3 | League Park II (1-2) | 7-8 | |
| » Starters: Red Faber vs Willie Mitchell | Fifth | 2 out |
| Friday, April 28 |
| » Lost to Indians (7-6), 2-1 | League Park II (1-3) | 7-9 | |
| » Starters: Lefty Williams vs Guy Morton | Fifth | 3 out |
| Saturday, April 29 |
| » Defeated Browns (5-8), 3-1 | Sportsman's Park III (1-0) | 8-9 | |
| » Starters: Reb Russell vs Eddie Plank | Sixth | 2½ out |
| Sunday, April 30 |
| » Defeated Browns (5-9), 6-2 | Sportsman's Park III (2-0) | 9-9 | Won 2 |
| » Starters: Jim Scott vs Bob Groom | Fifth | 1½ out |
| Tuesday, May 2 |
| » Defeated Browns (5-10), 5-4 | Sportsman's Park III (3-0) | 10-9 | Won 3 |
| » Starters: Red Faber vs Jim Park | Fifth | 1½ out |
| Wednesday, May 3 |
| Future White Sox Ken Silvestri is born in Chicago, IL. |
| Thursday, May 4 |
| » Lost to Indians (11-7), 2-0 | Comiskey Park I (5-4) | 10-10 | |
| » Starters: Fritz Coumbe vs Lefty Williams | Sixth | 2½ out |
| Friday, May 5 |
| » Lost to Indians (12-7), 3-2 | Comiskey Park I (5-5) | 10-11 | Lost 2 |
| » Starters: Stan Coveleski vs Reb Russell | Fifth | 3 out |
| Saturday, May 6 |
| » Lost to Indians (13-7), 4-1 | Comiskey Park I (5-6) | 10-12 | Lost 3 |
| » Starters: Guy Morton vs Jim Scott | Sixth | 4 out |
| Sunday, May 7 |
| » Lost to Indians (14-7), 5-2 | Comiskey Park I (5-7) | 10-13 | Lost 4 |
| » Starters: Fritz Coumbe vs Red Faber | Fifth | 5 out |
| Tuesday, May 9 |
| » Defeated Yankees (11-9), 5-4 | Polo Grounds V (1-0) | 11-13 | |
| » Starters: Lefty Williams vs Ray Caldwell | Fourth | 4½ out |
| Wednesday, May 10 |
| » Defeated Yankees (11-10), 5-2 | Polo Grounds V (2-0) | 12-13 | Won 2 |
| » Starters: Reb Russell vs Ray Keating | Fifth | 4½ out |
| Thursday, May 11 |
| » Lost to Yankees (12-10), 2-1 | Polo Grounds V (2-1) | 12-14 | |
| » Starters: Red Faber vs Nick Cullop | Fifth | 4½ out |
| Friday, May 12 |
| » Lost to Yankees (13-10), 2-0 | Polo Grounds V (2-2) | 12-15 | Lost 2 |
| » Starters: Dave Danforth vs George Mogridge | Sixth | 5½ out |
| Saturday, May 13 |
| » Lost to Red Sox (13-13), 3-2 | Fenway Park (0-1) | 12-16 | Lost 3 |
| » Starters: Eddie Cicotte vs Dutch Leonard | Fifth | 6½ out |
| Thursday, May 18 |
| » Lost to Athletics (11-16), 5-1 | Shibe Park (0-1) | 12-17 | Lost 4 |
| » Starters: Red Faber vs Elmer Myers | Sixth | 8 out |
| Friday, May 19 |
| » Lost to Athletics (12-16), 1-0 | Shibe Park (0-2) | 12-18 | Lost 5 |
| » Starters: Eddie Cicotte vs Bullet Joe Bush | Eighth | 9 out |
| Saturday, May 20 |
| » Defeated Athletics (12-17), 11-0 | Shibe Park (1-2) | 13-18 | |
| » Starters: Joe Benz vs Cap Crowell | Sixth | 8 out |
| Monday, May 22 |
| » Lost to Senators (21-11), 2-0 | Griffith Stadium (0-1) | 13-19 | |
| » Starters: Mellie Wolfgang vs Harry Harper | Eighth | 8 out |
| Wednesday, May 24 |
| » Defeated Senators (21-12), 4-1 | Griffith Stadium (1-1) | 14-19 | |
| » Starters: Red Faber vs Bert Gallia | Fifth | 7½ out |
| Thursday, May 25 |
| » Tied Senators, 3-3 | Griffith Stadium (1-1) | 14-19 | |
| » Starters: Joe Benz vs Harry Harper | Fifth | 7½ out |
| Sunday, May 28 |
| » Defeated Indians (23-13), 2-0 | Comiskey Park I (6-7) | 15-19 | Won 2 |
| » Starters: Fritz Coumbe vs Jim Scott | Fifth | 7½ out |
| » Defeated Indians (23-14), 2-0 | Comiskey Park I (7-7) | 16-19 | Won 3 |
| » Starters: Guy Morton vs Red Faber | Fifth | 7½ out |
| Tuesday, May 30 |
| » Defeated Tigers (16-22), 3-1 | Tiger Stadium (2-3) | 17-19 | Won 4 |
| » Starters: Lefty Williams vs Earl Hamilton | Fifth | 6½ out |
| » Lost to Tigers (17-22), 9-8 | Tiger Stadium (2-4) | 17-20 | |
| » Starters: Mellie Wolfgang vs Harry Coveleski | Fifth | 6½ out |
| Wednesday, May 31 |
| » Lost to Tigers (18-22), 7-4 | Tiger Stadium (2-5) | 17-21 | Lost 2 |
| » Starters: Dave Danforth vs Hooks Dauss | Fifth | 6½ out |
| Thursday, June 1 |
| » Defeated Tigers (18-23), 6-3 | Tiger Stadium (3-5) | 18-21 | |
| » Starters: Red Faber vs George Cunningham | Fifth | 6 out |
| Saturday, June 3 |
| » Lost to Yankees (23-16), 5-0 | Comiskey Park I (7-8) | 18-22 | |
| » Starters: George Mogridge vs Jim Scott | Sixth | 6½ out |
| Sunday, June 4 |
| » Defeated Yankees (23-17), 12-4 | Comiskey Park I (8-8) | 19-22 | |
| » Starters: Ray Fisher vs Reb Russell | Sixth | 6½ out |
| Monday, June 5 |
| » Lost to Yankees (24-17), 3-2 | Comiskey Park I (8-9) | 19-23 | |
| » Starters: Nick Cullop vs Joe Benz | Sixth | 6½ out |
| Tuesday, June 6 |
| Future White Sox Dario Lodigiani is born in San Francisco, CA. |
| Saturday, June 10 |
| » Defeated Senators (25-20), 2-1 | Comiskey Park I (9-9) | 20-23 | |
| » Starters: Harry Harper vs Mellie Wolfgang | Sixth | 6 out |
| Sunday, June 11 |
| » Defeated Senators (25-21), 5-0 | Comiskey Park I (10-9) | 21-23 | Won 2 |
| » Starters: Joe Boehling vs Jim Scott | Sixth | 6 out |
| Monday, June 12 |
| » Defeated Senators (25-22), 3-0 | Comiskey Park I (11-9) | 22-23 | Won 3 |
| » Starters: Bert Gallia vs Joe Benz | Sixth | 6 out |
| Tuesday, June 13 |
| » Lost to Senators (26-22), 3-2 | Comiskey Park I (11-10) | 22-24 | |
| » Starters: Harry Harper vs Ed Walsh | Sixth | 7 out |
| Wednesday, June 14 |
| » Defeated Senators (26-23), 4-1 | Comiskey Park I (12-10) | 23-24 | |
| » Starters: Walter Johnson vs Jim Scott | Sixth | 6½ out |
| Thursday, June 15 |
| » Lost to Red Sox (26-24), 2-1 | Comiskey Park I (12-11) | 23-25 | |
| » Starters: Dutch Leonard vs Reb Russell | Sixth | 7½ out |
| Future White Sox Bud Stewart is born in Sacramento, CA. |
| Friday, June 16 |
| » Defeated Red Sox (26-25), 7-4 | Comiskey Park I (13-11) | 24-25 | |
| » Starters: Vean Gregg vs Lefty Williams | Sixth | 7 out |
| Saturday, June 17 |
| » Defeated Red Sox (26-26), 5-0 | Comiskey Park I (14-11) | 25-25 | Won 2 |
| » Starters: Babe Ruth vs Joe Benz | Fifth | 6 out |
| Sunday, June 18 |
| » Lost to Red Sox (27-26), 3-1 | Comiskey Park I (14-12) | 25-26 | |
| » Starters: Ernie Shore vs Jim Scott | Sixth | 6 out |
| Tuesday, June 20 |
| » Defeated Browns (22-31), 4-2 | Sportsman's Park III (4-0) | 26-26 | |
| » Starters: Lefty Williams vs Eddie Plank | Fifth | 4½ out |
| Wednesday, June 21 |
| » Lost to Browns (23-31), 11-1 | Sportsman's Park III (4-1) | 26-27 | |
| » Starters: Dave Danforth vs Carl Weilman | Fifth | 5 out |
| » Lost to Browns (24-31), 2-1 | Sportsman's Park III (4-2) | 26-28 | Lost 2 |
| » Starters: Jim Scott vs Ernie Koob | Fifth | 5 out |
| Thursday, June 22 |
| » Defeated Browns (24-32), 2-0 | Sportsman's Park III (5-2) | 27-28 | |
| » Starters: Reb Russell vs George Sisler | Sixth | 5 out |
| Saturday, June 24 |
| » Defeated Browns (24-33), 5-4 | Sportsman's Park III (6-2) | 28-28 | Won 2 |
| » Starters: Lefty Williams vs Eddie Plank | Sixth | 5 out |
| Sunday, June 25 |
| » Defeated Indians (34-25), 4-3 | Comiskey Park I (15-12) | 29-28 | Won 3 |
| » Starters: Fritz Coumbe vs Jim Scott | Sixth | 4 out |
| Monday, June 26 |
| » Lost to Indians (35-25), 2-0 | League Park II (1-4) | 29-29 | |
| » Starters: Dave Danforth vs Fred Beebe | Fifth | 5 out |
| Tuesday, June 27 |
| » Defeated Indians (35-26), 4-2 | League Park II (2-4) | 30-29 | |
| » Starters: Lefty Williams vs Jim Bagby | Sixth | 4 out |
| Wednesday, June 28 |
| » Defeated Indians (35-27), 5-1 | League Park II (3-4) | 31-29 | Won 2 |
| » Starters: Reb Russell vs Stan Coveleski | Fifth | 3½ out |
| Thursday, June 29 |
| » Defeated Tigers (34-31), 8-2 | Comiskey Park I (16-12) | 32-29 | Won 3 |
| » Starters: Harry Coveleski vs Mellie Wolfgang | Fourth | 3½ out |
| Friday, June 30 |
| » Defeated Tigers (34-32), 5-2 | Comiskey Park I (17-12) | 33-29 | Won 4 |
| » Starters: Hooks Dauss vs Jim Scott | Third | 3½ out |
| Saturday, July 1 |
| » Defeated Tigers (34-33), 6-0 | Comiskey Park I (18-12) | 34-29 | Won 5 |
| » Starters: Bill James vs Lefty Williams | Third | 3½ out |
| Sunday, July 2 |
| » Defeated Tigers (34-34), 1-0 | Comiskey Park I (19-12) | 35-29 | Won 6 |
| » Starters: Harry Coveleski vs Reb Russell | Third | 3 out |
| Monday, July 3 |
| » Defeated Browns (29-39), 3-2 | Comiskey Park I (20-12) | 36-29 | Won 7 |
| » Starters: Carl Weilman vs Mellie Wolfgang | Third | 3 out |
| Tuesday, July 4 |
| » Lost to Browns (30-39), 2-1 | Comiskey Park I (20-13) | 36-30 | |
| » Starters: Ernie Koob vs Jim Scott | Third | 3 out |
| » Defeated Browns (30-40), 7-6 | Comiskey Park I (21-13) | 37-30 | |
| » Starters: Earl Hamilton vs Lefty Williams | Third | 3 out |
| Thursday, July 6 |
| » Lost to Yankees (42-27), 4-3 | Polo Grounds V (2-3) | 37-31 | |
| » Starters: Reb Russell vs Nick Cullop | Fourth | 4½ out |
| Friday, July 7 |
| » Lost to Yankees (43-27), 4-3 | Polo Grounds V (2-4) | 37-32 | Lost 2 |
| » Starters: Mellie Wolfgang vs George Mogridge | Fourth | 5½ out |
| Saturday, July 8 |
| » Defeated Yankees (43-28), 2-1 | Polo Grounds V (3-4) | 38-32 | |
| » Starters: Eddie Cicotte vs Ray Caldwell | Fourth | 4½ out |
| Monday, July 10 |
| » Defeated Red Sox (39-33), 4-0 | Fenway Park (1-1) | 39-32 | Won 2 |
| » Starters: Lefty Williams vs Dutch Leonard | Third | 3 out |
| » Defeated Red Sox (39-34), 3-0 | Fenway Park (2-1) | 40-32 | Won 3 |
| » Starters: Reb Russell vs Carl Mays | Third | 3 out |
| Tuesday, July 11 |
| » Lost to Red Sox (40-34), 5-3 | Fenway Park (2-2) | 40-33 | |
| » Starters: Dave Danforth vs Babe Ruth | Fourth | 4 out |
| » Lost to Red Sox (41-34), 3-1 | Fenway Park (2-3) | 40-34 | Lost 2 |
| » Starters: Mellie Wolfgang vs Babe Ruth | Fourth | 4 out |
| Wednesday, July 12 |
| » Lost to Red Sox (42-34), 2-1 | Fenway Park (2-4) | 40-35 | Lost 3 |
| » Starters: Reb Russell vs Ernie Shore | Fourth | 4½ out |
| » Lost to Red Sox (43-34), 3-1 | Fenway Park (2-5) | 40-36 | Lost 4 |
| » Starters: Lefty Williams vs Dutch Leonard | Fourth | 4½ out |
| Saturday, July 15 |
| » Defeated Athletics (18-55), 4-1 | Shibe Park (2-2) | 41-36 | |
| » Starters: Jim Scott vs Tom Sheehan | Fourth | 3 out |
| » Defeated Athletics (18-56), 1-0 | Shibe Park (3-2) | 42-36 | Won 2 |
| » Starters: Joe Benz vs Bullet Joe Bush | Fourth | 3 out |
| Tuesday, July 18 |
| » Defeated Athletics (18-57), 9-2 | Shibe Park (4-2) | 43-36 | Won 3 |
| » Starters: Eddie Cicotte vs Red Lanning | Fourth | 2½ out |
| » Defeated Athletics (18-58), 3-2 | Shibe Park (5-2) | 44-36 | Won 4 |
| » Starters: Jim Scott vs Elmer Myers | Fourth | 2½ out |
| Wednesday, July 19 |
| » Defeated Senators (43-39), 6-3 | Griffith Stadium (2-1) | 45-36 | Won 5 |
| » Starters: Mellie Wolfgang vs Doc Ayers | Fourth | 3½ out |
| » Lost to Senators (44-39), 6-2 | Griffith Stadium (2-2) | 45-37 | |
| » Starters: Joe Benz vs Walter Johnson | Fourth | 3½ out |
| Future White Sox Phil Cavarretta is born in Chicago, IL. |
| Thursday, July 20 |
| » Lost to Senators (45-39), 4-3 | Griffith Stadium (2-3) | 45-38 | Lost 2 |
| » Starters: Lefty Williams vs Joe Boehling | Fifth | 4 out |
| » Lost to Senators (46-39), 2-1 | Griffith Stadium (2-4) | 45-39 | Lost 3 |
| » Starters: Reb Russell vs Harry Harper | Fifth | 4 out |
| Friday, July 21 |
| » Defeated Senators (46-40), 7-5 | Griffith Stadium (3-4) | 46-39 | |
| » Starters: Jim Scott vs George Dumont | Fourth | 3½ out |
| Saturday, July 22 |
| » Lost to Senators (47-40), 2-1 | Griffith Stadium (3-5) | 46-40 | |
| » Starters: Joe Benz vs Bert Gallia | Fifth | 4½ out |
| Sunday, July 23 |
| » Defeated Tigers (46-44), 12-9 | Tiger Stadium (4-5) | 47-40 | |
| » Starters: Lefty Williams vs Bernie Boland | Fourth | 4 out |
| Monday, July 24 |
| » Defeated Tigers (46-45), 3-2 | Tiger Stadium (5-5) | 48-40 | Won 2 |
| » Starters: Mellie Wolfgang vs Harry Coveleski | Fourth | 3½ out |
| Tuesday, July 25 |
| » Defeated Yankees (51-37), 13-8 | Comiskey Park I (22-13) | 49-40 | Won 3 |
| » Starters: Ray Caldwell vs Eddie Cicotte | Fourth | 2½ out |
| Wednesday, July 26 |
| » Defeated Yankees (51-38), 2-0 | Comiskey Park I (23-13) | 50-40 | Won 4 |
| » Starters: George Mogridge vs Eddie Cicotte | Third | 1½ out |
| Thursday, July 27 |
| » Lost to Yankees (52-38), 8-6 | Comiskey Park I (23-14) | 50-41 | |
| » Starters: Allen Russell vs Jim Scott | Third | 2½ out |
| Friday, July 28 |
| » Lost to Yankees (53-38), 5-3 | Comiskey Park I (23-15) | 50-42 | Lost 2 |
| » Starters: Bob Shawkey vs Lefty Williams | Third | 3½ out |
| Saturday, July 29 |
| » Defeated Athletics (19-67), 6-1 | Comiskey Park I (24-15) | 51-42 | |
| » Starters: Elmer Myers vs Red Faber | Third | 1½ out |
| » Defeated Athletics (19-68), 6-4 | Comiskey Park I (25-15) | 52-42 | Won 2 |
| » Starters: Bullet Joe Bush vs Joe Benz | Third | 1½ out |
| Sunday, July 30 |
| » Defeated Athletics (19-69), 10-1 | Comiskey Park I (26-15) | 53-42 | Won 3 |
| » Starters: Red Lanning vs Eddie Cicotte | Second | 1½ out |
| » Defeated Athletics (19-70), 7-0 | Comiskey Park I (27-15) | 54-42 | Won 4 |
| » Starters: Marsh Williams vs Mellie Wolfgang | Second | 1½ out |
| Monday, July 31 |
| » Defeated Athletics (19-71), 4-3 | Comiskey Park I (28-15) | 55-42 | Won 5 |
| » Starters: Tom Sheehan vs Lefty Williams | Second | 1½ out |
| Tuesday, August 1 |
| » Defeated Athletics (19-72), 3-0 | Comiskey Park I (29-15) | 56-42 | Won 6 |
| » Starters: Jack Nabors vs Reb Russell | Second | 2 out |
| » Defeated Athletics (19-73), 3-2 | Comiskey Park I (30-15) | 57-42 | Won 7 |
| » Starters: Elmer Myers vs Jim Scott | Second | 2 out |
| Wednesday, August 2 |
| » Defeated Athletics (19-74), 8-2 | Comiskey Park I (31-15) | 58-42 | Won 8 |
| » Starters: Jing Johnson vs Eddie Cicotte | Second | 2 out |
| Friday, August 4 |
| » Defeated Senators (49-48), 3-2 | Comiskey Park I (32-15) | 59-42 | Won 9 |
| » Starters: Walter Johnson vs Red Faber | First | -- |
| » Lost to Senators (50-48), 8-3 | Comiskey Park I (32-16) | 59-43 | |
| » Starters: Harry Harper vs Mellie Wolfgang | First | -- |
| Saturday, August 5 |
| » Defeated Senators (50-49), 7-0 | Comiskey Park I (33-16) | 60-43 | |
| » Starters: Jim Shaw vs Eddie Cicotte | First | -- |
| Sunday, August 6 |
| » Lost to Senators (51-49), 2-1 | Comiskey Park I (33-17) | 60-44 | |
| » Starters: Joe Boehling vs Mellie Wolfgang | First | -- |
| Monday, August 7 |
| » Defeated Red Sox (58-44), 7-1 | Comiskey Park I (34-17) | 61-44 | |
| » Starters: Dutch Leonard vs Reb Russell | First | -- |
| Tuesday, August 8 |
| » Lost to Red Sox (59-44), 6-4 | Comiskey Park I (34-18) | 61-45 | |
| » Starters: Carl Mays vs Red Faber | First | -- |
| Wednesday, August 9 |
| » Lost to Red Sox (60-44), 3-1 | Comiskey Park I (34-19) | 61-46 | Lost 2 |
| » Starters: Ernie Shore vs Jim Scott | Second | 1½ out |
| Thursday, August 10 |
| » Lost to Red Sox (61-44), 11-5 | Comiskey Park I (34-20) | 61-47 | Lost 3 |
| » Starters: Rube Foster vs Reb Russell | Third | 1½ out |
| Friday, August 11 |
| » Lost to Tigers (59-51), 2-0 | Comiskey Park I (34-21) | 61-48 | Lost 4 |
| » Starters: Harry Coveleski vs Mellie Wolfgang | Third | 2 out |
| Saturday, August 12 |
| » Defeated Tigers (59-52), 3-0 | Comiskey Park I (35-21) | 62-48 | |
| » Starters: Hooks Dauss vs Red Faber | Second | 2 out |
| Sunday, August 13 |
| » Lost to Tigers (60-52), 9-4 | Comiskey Park I (35-22) | 62-49 | |
| » Starters: Bill James vs Jim Scott | Third | 2½ out |
| Wednesday, August 16 |
| » Lost to Red Sox (64-45), 5-4 | Fenway Park (2-6) | 62-50 | Lost 2 |
| » Starters: Red Faber vs Dutch Leonard | Third | 4½ out |
| » Lost to Red Sox (65-45), 2-1 | Fenway Park (2-7) | 62-51 | Lost 3 |
| » Starters: Lefty Williams vs Rube Foster | Third | 4½ out |
| Thursday, August 17 |
| » Defeated Red Sox (65-46), 7-0 | Fenway Park (3-7) | 63-51 | |
| » Starters: Reb Russell vs Carl Mays | Third | 3½ out |
| Friday, August 18 |
| » Defeated Red Sox (65-47), 11-6 | Fenway Park (4-7) | 64-51 | Won 2 |
| » Starters: Lefty Williams vs Dutch Leonard | Second | 2½ out |
| Saturday, August 19 |
| » Defeated Yankees (60-53), 3-1 | Polo Grounds V (4-4) | 65-51 | Won 3 |
| » Starters: Eddie Cicotte vs George Mogridge | Second | 2½ out |
| Monday, August 21 |
| » Lost to Yankees (61-53), 6-2 | Polo Grounds V (4-5) | 65-52 | |
| » Starters: Jim Scott vs Nick Cullop | Second | 3½ out |
| Tuesday, August 22 |
| » Lost to Yankees (62-53), 7-6 | Polo Grounds V (4-6) | 65-53 | Lost 2 |
| » Starters: Eddie Cicotte vs Bob Shawkey | Second | 4½ out |
| Wednesday, August 23 |
| » Lost to Yankees (63-53), 5-4 | Polo Grounds V (4-7) | 65-54 | Lost 3 |
| » Starters: Reb Russell vs George Mogridge | Second | 5½ out |
| Thursday, August 24 |
| » Lost to Senators (56-60), 8-3 | Griffith Stadium (3-6) | 65-55 | Lost 4 |
| » Starters: Red Faber vs Bert Gallia | Second | 6½ out |
| Friday, August 25 |
| » Lost to Senators (57-60), 5-2 | Griffith Stadium (3-7) | 65-56 | Lost 5 |
| » Starters: Lefty Williams vs Harry Harper | Fourth | 6½ out |
| Saturday, August 26 |
| » Defeated Senators (57-61), 5-3 | Griffith Stadium (4-7) | 66-56 | |
| » Starters: Reb Russell vs Doc Ayers | Fourth | 5½ out |
| Monday, August 28 |
| » Defeated Athletics (26-92), 1-0 | Shibe Park (6-2) | 67-56 | Won 2 |
| » Starters: Joe Benz vs Elmer Myers | Second | 5 out |
| Tuesday, August 29 |
| » Lost to Athletics (27-92), 9-2 | Shibe Park (6-3) | 67-57 | |
| » Starters: Eddie Cicotte vs Jing Johnson | Fourth | 4½ out |
| Wednesday, August 30 |
| » Defeated Athletics (27-93), 7-3 | Shibe Park (7-3) | 68-57 | |
| » Starters: Red Faber vs Tom Sheehan | Third | 4½ out |
| Thursday, August 31 |
| » Defeated Athletics (27-94), 7-1 | Shibe Park (8-3) | 69-57 | Won 2 |
| » Starters: Joe Benz vs Bullet Joe Bush | Third | 3½ out |
| Saturday, September 2 |
| » Lost to Tigers (71-57), 2-1 | Tiger Stadium (5-6) | 69-58 | |
| » Starters: Reb Russell vs Harry Coveleski | Third | 4 out |
| Sunday, September 3 |
| » Defeated Browns (69-60), 1-0 | Sportsman's Park III (7-2) | 70-58 | |
| » Starters: Red Faber vs Carl Weilman | Third | 3½ out |
| Monday, September 4 |
| » Defeated Browns (69-61), 3-2 | Sportsman's Park III (8-2) | 71-58 | Won 2 |
| » Starters: Lefty Williams vs Ernie Koob | Third | 2½ out |
| » Defeated Browns (69-62), 2-1 | Sportsman's Park III (9-2) | 72-58 | Won 3 |
| » Starters: Joe Benz vs Eddie Plank | Third | 2½ out |
| Wednesday, September 6 |
| » Defeated Indians (68-64), 4-3 | Comiskey Park I (36-22) | 73-58 | Won 4 |
| » Starters: Joe Boehling vs Reb Russell | Third | 2½ out |
| Thursday, September 7 |
| » Defeated Indians (68-65), 5-3 | Comiskey Park I (37-22) | 74-58 | Won 5 |
| » Starters: Jim Bagby vs Red Faber | Third | 2½ out |
| Friday, September 8 |
| » Defeated Indians (68-66), 3-2 | Comiskey Park I (38-22) | 75-58 | Won 6 |
| » Starters: Fritz Coumbe vs Joe Benz | Third | 2 out |
| Saturday, September 9 |
| » Defeated Indians (68-67), 5-4 | Comiskey Park I (39-22) | 76-58 | Won 7 |
| » Starters: Otis Lambeth vs Lefty Williams | Third | 1½ out |
| Sunday, September 10 |
| » Lost to Browns (71-65), 5-2 | Comiskey Park I (39-23) | 76-59 | |
| » Starters: Eddie Plank vs Reb Russell | Third | 2 out |
| Monday, September 11 |
| » Defeated Browns (71-66), 5-2 | Comiskey Park I (40-23) | 77-59 | |
| » Starters: Ernie Koob vs Red Faber | Third | 2 out |
| Tuesday, September 12 |
| » Lost to Browns (72-66), 5-3 | Comiskey Park I (40-24) | 77-60 | |
| » Starters: Carl Weilman vs Joe Benz | Third | 2 out |
| Future White Sox Ralph Hamner is born in Gibsland, LA. |
| Wednesday, September 13 |
| » Defeated Browns (72-67), 9-8 | Comiskey Park I (41-24) | 78-60 | |
| » Starters: Earl Hamilton vs Lefty Williams | Third | 1½ out |
| Thursday, September 14 |
| » Defeated Senators (68-67), 7-5 | Comiskey Park I (42-24) | 79-60 | Won 2 |
| » Starters: Bert Gallia vs Red Faber | Third | 1½ out |
| » Major-league debuts: Claude Thomas (Senators) |
| Friday, September 15 |
| » Defeated Senators (68-68), 3-2 | Comiskey Park I (43-24) | 80-60 | Won 3 |
| » Starters: Jim Shaw vs Eddie Cicotte | Third | 1½ out |
| Saturday, September 16 |
| » Defeated Red Sox (79-59), 6-4 | Comiskey Park I (44-24) | 81-60 | Won 4 |
| » Starters: Dutch Leonard vs Lefty Williams | Second | ½ out |
| Sunday, September 17 |
| » Lost to Red Sox (80-59), 6-2 | Comiskey Park I (44-25) | 81-61 | |
| » Starters: Babe Ruth vs Red Faber | Third | 1½ out |
| Monday, September 18 |
| » Lost to Red Sox (81-59), 4-3 | Comiskey Park I (44-26) | 81-62 | Lost 2 |
| » Starters: Ernie Shore vs Lefty Williams | Third | 1½ out |
| Tuesday, September 19 |
| » Defeated Athletics (31-109), 5-4 | Comiskey Park I (45-26) | 82-62 | |
| » Starters: Jack Nabors vs Joe Benz | Third | 1½ out |
| Wednesday, September 20 |
| » Defeated Athletics (31-110), 8-7 | Comiskey Park I (46-26) | 83-62 | Won 2 |
| » Starters: Jing Johnson vs Reb Russell | Second | 1½ out |
| Thursday, September 21 |
| » Lost to Athletics (32-110), 8-0 | Comiskey Park I (46-27) | 83-63 | |
| » Starters: Bullet Joe Bush vs Red Faber | Second | 2½ out |
| Friday, September 22 |
| » Defeated Yankees (75-69), 6-3 | Comiskey Park I (47-27) | 84-63 | |
| » Starters: George Mogridge vs Eddie Cicotte | Second | 2½ out |
| Saturday, September 23 |
| » Lost to Yankees (76-69), 7-2 | Comiskey Park I (47-28) | 84-64 | |
| » Starters: Bob Shawkey vs Reb Russell | Second | 3½ out |
| Sunday, September 24 |
| » Defeated Yankees (76-70), 2-1 | Comiskey Park I (48-28) | 85-64 | |
| » Starters: Nick Cullop vs Lefty Williams | Second | 2½ out |
| Monday, September 25 |
| » Defeated Yankees (76-71), 5-1 | Comiskey Park I (49-28) | 86-64 | Won 2 |
| » Starters: Allen Russell vs Eddie Cicotte | Second | 2½ out |
| Saturday, September 30 |
| » Defeated Indians (76-75), 7-2 | League Park II (4-4) | 87-64 | Won 3 |
| » Starters: Reb Russell vs Jim Bagby | Second | 2½ out |
| » Defeated Indians (76-76), 7-3 | League Park II (5-4) | 88-64 | Won 4 |
| » Starters: Lefty Williams vs Joe Boehling | Second | 2½ out |
| Sunday, October 1 |
| » Lost to Indians (77-76), 2-0 | League Park II (5-5) | 88-65 | |
| » Starters: Red Faber vs Fritz Coumbe | Second | 2½ out |
| » Defeated Indians (77-77), 8-4 | League Park II (6-5) | 89-65 | |
| » Starters: Eddie Cicotte vs Ken Penner | Second | 2½ out |
| Tuesday, October 3 |
| » Major-league debuts: Axel Lindstrom (Athletics) |
| Tuesday, October 10 |
| Future White Sox Floyd Baker is born in Luray, VA. |
| Sunday, November 26 |
| Future White Sox Bob Elliott is born in San Francisco, CA. |
| Wednesday, December 13 |
| Future White Sox Hank Majeski is born in Staten Island, NY. |
Game information provided by Retrosheet (www.retrosheet.org) |
