| Saturday, February 5 |
| Former Tiger Ed Irvin dies in Philadelphia, PA at the age of 35. |
| Saturday, March 18 |
| Future Tiger Eddie Lake is born in Antioch, CA. |
| Wednesday, April 12 |
| » Defeated White Sox (0-1), 4-0 | Comiskey Park I (1-0) | 1-0 | |
| » Starters: Harry Coveleski vs Reb Russell | First | -- |
| » Major-league debuts: Zeb Terry (White Sox) |
| Thursday, April 13 |
| » Lost to White Sox (1-1), 8-6 | Comiskey Park I (1-1) | 1-1 | |
| » Starters: Hooks Dauss vs Dave Danforth | Third | 1 out |
| Friday, April 14 |
| » Lost to White Sox (2-1), 7-2 | Comiskey Park I (1-2) | 1-2 | Lost 2 |
| » Starters: George Cunningham vs Red Faber | Fourth | 1½ out |
| » Major-league debuts: George Cunningham (Tigers) |
| Saturday, April 15 |
| » Lost to White Sox (3-1), 9-4 | Comiskey Park I (1-3) | 1-3 | Lost 3 |
| » Starters: Bernie Boland vs Eddie Cicotte | Sixth | 2½ out |
| » Major-league debuts: George Harper (Tigers) |
| Sunday, April 16 |
| » Lost to Indians (2-2), 4-3 | League Park II (0-1) | 1-4 | Lost 4 |
| » Starters: Hooks Dauss vs Jim Bagby | Sixth | 3 out |
| Monday, April 17 |
| » Defeated Indians (2-3), 3-1 | League Park II (1-1) | 2-4 | |
| » Starters: George Cunningham vs Stan Coveleski | Seventh | 3 out |
| Tuesday, April 18 |
| » Defeated Indians (2-4), 4-3 | League Park II (2-1) | 3-4 | Won 2 |
| » Starters: Harry Coveleski vs Guy Morton | Sixth | 2 out |
| Thursday, April 20 |
| » Defeated White Sox (5-4), 2-1 | Tiger Stadium (1-0) | 4-4 | Won 3 |
| » Starters: Mellie Wolfgang vs Harry Coveleski | Fifth | 2 out |
| Friday, April 21 |
| » Defeated White Sox (5-5), 3-2 | Tiger Stadium (2-0) | 5-4 | Won 4 |
| » Starters: Dave Danforth vs Hooks Dauss | Fourth | 1 out |
| Sunday, April 23 |
| » Lost to White Sox (6-5), 3-2 | Tiger Stadium (2-1) | 5-5 | |
| » Starters: Red Faber vs Bill James | Fifth | 1½ out |
| Monday, April 24 |
| » Defeated White Sox (6-6), 4-2 | Tiger Stadium (3-1) | 6-5 | |
| » Starters: Jim Scott vs Harry Coveleski | Third | 1 out |
| Thursday, April 27 |
| » Defeated Browns (5-6), 7-2 | Sportsman's Park III (1-0) | 7-5 | Won 2 |
| » Starters: George Cunningham vs Carl Weilman | Third | ½ out |
| Friday, April 28 |
| » Defeated Browns (5-7), 6-5 | Sportsman's Park III (2-0) | 8-5 | Won 3 |
| » Starters: Harry Coveleski vs Dave Davenport | Second | ½ out |
| Saturday, April 29 |
| » Defeated Indians (7-7), 5-4 | Tiger Stadium (4-1) | 9-5 | Won 4 |
| » Starters: Ed Klepfer vs Jean Dubuc | First | -- |
| Sunday, April 30 |
| » Lost to Indians (8-7), 12-6 | Tiger Stadium (4-2) | 9-6 | |
| » Starters: Jim Bagby vs Bill James | First | -- |
| Monday, May 1 |
| » Lost to Indians (9-7), 2-0 | Tiger Stadium (4-3) | 9-7 | Lost 2 |
| » Starters: Stan Coveleski vs Hooks Dauss | Second | ½ out |
| Tuesday, May 2 |
| » Lost to Indians (10-7), 6-1 | Tiger Stadium (4-4) | 9-8 | Lost 3 |
| » Starters: Guy Morton vs Harry Coveleski | Fourth | 1½ out |
| Thursday, May 4 |
| » Lost to Browns (6-10), 7-6 | Tiger Stadium (4-5) | 9-9 | Lost 4 |
| » Starters: Dave Davenport vs Jean Dubuc | Fifth | 2½ out |
| Friday, May 5 |
| » Lost to Browns (7-10), 5-4 | Tiger Stadium (4-6) | 9-10 | Lost 5 |
| » Starters: Eddie Plank vs George Cunningham | Sixth | 3 out |
| Sunday, May 7 |
| » Defeated Browns (7-11), 2-1 | Tiger Stadium (5-6) | 10-10 | |
| » Starters: Carl Weilman vs Harry Coveleski | Fourth | 3½ out |
| Monday, May 8 |
| » Lost to Indians (15-7), 3-1 | League Park II (2-2) | 10-11 | |
| » Starters: Jean Dubuc vs Jim Bagby | Third | 4½ out |
| Tuesday, May 9 |
| » Defeated Athletics (7-13), 16-2 | Shibe Park (1-0) | 11-11 | |
| » Starters: George Cunningham vs Jack Nabors | Third | 3½ out |
| Wednesday, May 10 |
| » Defeated Athletics (7-14), 9-3 | Shibe Park (2-0) | 12-11 | Won 2 |
| » Starters: George Boehler vs Tom Sheehan | Fourth | 3½ out |
| Thursday, May 11 |
| » Lost to Athletics (8-14), 3-2 | Shibe Park (2-1) | 12-12 | |
| » Starters: Harry Coveleski vs Elmer Myers | Fourth | 3½ out |
| Friday, May 12 |
| » Defeated Athletics (8-15), 8-6 | Shibe Park (3-1) | 13-12 | |
| » Starters: Bill James vs Cap Crowell | Fourth | 3½ out |
| Future Tiger Hank Borowy is born in Bloomfield, NJ. |
| Saturday, May 13 |
| » Lost to Senators (15-9), 3-2 | Griffith Stadium (0-1) | 13-13 | |
| » Starters: George Cunningham vs Walter Johnson | Fourth | 4½ out |
| Monday, May 15 |
| » Lost to Senators (16-9), 6-5 | Griffith Stadium (0-2) | 13-14 | Lost 2 |
| » Starters: Harry Coveleski vs Joe Boehling | Fifth | 5½ out |
| Tuesday, May 16 |
| » Lost to Senators (17-9), 15-3 | Griffith Stadium (0-3) | 13-15 | Lost 3 |
| » Starters: George Boehler vs Bert Gallia | Fifth | 6 out |
| » Major-league debuts: Patsy Gharrity (Senators) |
| Wednesday, May 17 |
| » Lost to Senators (18-9), 6-4 | Griffith Stadium (0-4) | 13-16 | Lost 4 |
| » Starters: Jean Dubuc vs Harry Harper | Fifth | 6½ out |
| Friday, May 19 |
| » Tied Yankees, 2-2 | Polo Grounds V (0-0) | 13-16 | |
| » Starters: Harry Coveleski vs Nick Cullop | Fifth | 7½ out |
| Saturday, May 20 |
| » Lost to Yankees (14-12), 2-1 | Polo Grounds V (0-1) | 13-17 | Lost 5 |
| » Starters: George Cunningham vs Ray Caldwell | Fifth | 7½ out |
| Monday, May 22 |
| » Lost to Red Sox (15-15), 2-1 | Fenway Park (0-1) | 13-18 | Lost 6 |
| » Starters: Hooks Dauss vs Vean Gregg | Sixth | 7½ out |
| Wednesday, May 24 |
| » Lost to Red Sox (16-15), 4-0 | Fenway Park (0-2) | 13-19 | Lost 7 |
| » Starters: Jean Dubuc vs Babe Ruth | Seventh | 8 out |
| Thursday, May 25 |
| » Lost to Red Sox (17-15), 5-2 | Fenway Park (0-3) | 13-20 | Lost 8 |
| » Starters: George Cunningham vs Ernie Shore | Seventh | 8½ out |
| Saturday, May 27 |
| » Defeated Browns (12-21), 3-1 | Tiger Stadium (6-6) | 14-20 | |
| » Starters: Carl Weilman vs Harry Coveleski | Sixth | 9 out |
| Sunday, May 28 |
| » Defeated Browns (12-22), 6-3 | Tiger Stadium (7-6) | 15-20 | Won 2 |
| » Starters: Bob Groom vs Hooks Dauss | Sixth | 8½ out |
| Monday, May 29 |
| » Lost to Browns (13-22), 8-2 | Tiger Stadium (7-7) | 15-21 | |
| » Starters: Carl Weilman vs George Cunningham | Sixth | 8½ out |
| » Defeated Browns (13-23), 17-6 | Tiger Stadium (8-7) | 16-21 | |
| » Starters: Eddie Plank vs Jean Dubuc | Sixth | 8½ out |
| Tuesday, May 30 |
| » Lost to White Sox (17-19), 3-1 | Tiger Stadium (8-8) | 16-22 | |
| » Starters: Lefty Williams vs Earl Hamilton | Sixth | 7½ out |
| » Defeated White Sox (17-20), 9-8 | Tiger Stadium (9-8) | 17-22 | |
| » Starters: Mellie Wolfgang vs Harry Coveleski | Sixth | 7½ out |
| Wednesday, May 31 |
| » Defeated White Sox (17-21), 7-4 | Tiger Stadium (10-8) | 18-22 | Won 2 |
| » Starters: Dave Danforth vs Hooks Dauss | Fourth | 6½ out |
| Thursday, June 1 |
| » Lost to White Sox (18-21), 6-3 | Tiger Stadium (10-9) | 18-23 | |
| » Starters: Red Faber vs George Cunningham | Sixth | 7 out |
| Saturday, June 3 |
| » Defeated Senators (24-17), 3-2 | Tiger Stadium (11-9) | 19-23 | |
| » Starters: Harry Harper vs Jean Dubuc | Fifth | 6½ out |
| Sunday, June 4 |
| » Defeated Senators (24-18), 4-3 | Tiger Stadium (12-9) | 20-23 | Won 2 |
| » Starters: Bert Gallia vs Earl Hamilton | Fifth | 6½ out |
| Monday, June 5 |
| » Defeated Senators (24-19), 3-2 | Tiger Stadium (13-9) | 21-23 | Won 3 |
| » Starters: Walter Johnson vs Harry Coveleski | Fifth | 5½ out |
| Tuesday, June 6 |
| » Defeated Red Sox (23-21), 3-0 | Tiger Stadium (14-9) | 22-23 | Won 4 |
| » Starters: Vean Gregg vs Hooks Dauss | Fifth | 5 out |
| Friday, June 9 |
| » Defeated Red Sox (23-22), 6-5 | Tiger Stadium (15-9) | 23-23 | Won 5 |
| » Starters: Babe Ruth vs Jean Dubuc | Fifth | 4 out |
| Sunday, June 11 |
| » Defeated Yankees (24-20), 4-1 | Tiger Stadium (16-9) | 24-23 | Won 6 |
| » Starters: Ray Caldwell vs Harry Coveleski | Fifth | 4½ out |
| Monday, June 12 |
| » Defeated Yankees (24-21), 8-6 | Tiger Stadium (17-9) | 25-23 | Won 7 |
| » Starters: Ray Fisher vs Earl Hamilton | Fourth | 4½ out |
| Tuesday, June 13 |
| » Lost to Yankees (25-21), 4-2 | Tiger Stadium (17-10) | 25-24 | |
| » Starters: Nick Cullop vs Earl Hamilton | Fifth | 5½ out |
| Wednesday, June 14 |
| » Defeated Yankees (25-22), 6-2 | Tiger Stadium (18-10) | 26-24 | |
| » Starters: George Mogridge vs Harry Coveleski | Fourth | 5 out |
| Thursday, June 15 |
| » Defeated Athletics (15-31), 5-1 | Tiger Stadium (19-10) | 27-24 | Won 2 |
| » Starters: Bullet Joe Bush vs Hooks Dauss | Third | 5 out |
| Friday, June 16 |
| » Defeated Athletics (15-32), 4-3 | Tiger Stadium (20-10) | 28-24 | Won 3 |
| » Starters: Jack Nabors vs Jean Dubuc | Third | 4½ out |
| Saturday, June 17 |
| » Defeated Athletics (15-33), 7-3 | Tiger Stadium (21-10) | 29-24 | Won 4 |
| » Starters: Elmer Myers vs George Cunningham | Third | 3½ out |
| Sunday, June 18 |
| » Defeated Athletics (15-34), 8-2 | Tiger Stadium (22-10) | 30-24 | Won 5 |
| » Starters: Tom Sheehan vs Earl Hamilton | Third | 2½ out |
| Tuesday, June 20 |
| » Defeated Indians (32-23), 2-1 | Tiger Stadium (23-10) | 31-24 | Won 6 |
| » Starters: Grover Lowdermilk vs Hooks Dauss | Third | 1 out |
| Wednesday, June 21 |
| » Defeated Indians (32-24), 3-0 | Tiger Stadium (24-10) | 32-24 | Won 7 |
| » Starters: Jim Bagby vs Harry Coveleski | First | -- |
| Thursday, June 22 |
| » Lost to Indians (33-24), 4-3 | Tiger Stadium (24-11) | 32-25 | |
| » Starters: Stan Coveleski vs Jean Dubuc | Third | 1 out |
| Saturday, June 24 |
| » Lost to Indians (34-24), 10-8 | Tiger Stadium (24-12) | 32-26 | Lost 2 |
| » Starters: Grover Lowdermilk vs Hooks Dauss | Third | 2 out |
| Sunday, June 25 |
| » Lost to Browns (25-33), 8-2 | Sportsman's Park III (2-1) | 32-27 | Lost 3 |
| » Starters: Harry Coveleski vs Carl Weilman | Fourth | 2½ out |
| » Lost to Browns (26-33), 3-1 | Sportsman's Park III (2-2) | 32-28 | Lost 4 |
| » Starters: Willie Mitchell vs Bob Groom | Fourth | 2½ out |
| Monday, June 26 |
| » Defeated Browns (26-34), 3-1 | Sportsman's Park III (3-2) | 33-28 | |
| » Starters: Harry Coveleski vs Earl Hamilton | Third | 2½ out |
| Tuesday, June 27 |
| » Lost to Browns (27-34), 5-3 | Sportsman's Park III (3-3) | 33-29 | |
| » Starters: Jean Dubuc vs Carl Weilman | Fourth | 2 out |
| » Defeated Browns (27-35), 5-2 | Sportsman's Park III (4-3) | 34-29 | |
| » Starters: Bill James vs Ernie Koob | Fourth | 2 out |
| Wednesday, June 28 |
| » Lost to Browns (28-35), 5-3 | Sportsman's Park III (4-4) | 34-30 | |
| » Starters: Willie Mitchell vs Eddie Plank | Fourth | 2½ out |
| Thursday, June 29 |
| » Lost to White Sox (32-29), 8-2 | Comiskey Park I (1-4) | 34-31 | Lost 2 |
| » Starters: Harry Coveleski vs Mellie Wolfgang | Sixth | 3½ out |
| Friday, June 30 |
| » Lost to White Sox (33-29), 5-2 | Comiskey Park I (1-5) | 34-32 | Lost 3 |
| » Starters: Hooks Dauss vs Jim Scott | Fifth | 4½ out |
| Saturday, July 1 |
| » Lost to White Sox (34-29), 6-0 | Comiskey Park I (1-6) | 34-33 | Lost 4 |
| » Starters: Bill James vs Lefty Williams | Sixth | 5½ out |
| Sunday, July 2 |
| » Lost to White Sox (35-29), 1-0 | Comiskey Park I (1-7) | 34-34 | Lost 5 |
| » Starters: Harry Coveleski vs Reb Russell | Sixth | 6 out |
| Monday, July 3 |
| » Lost to Indians (39-28), 6-4 | League Park II (2-3) | 34-35 | Lost 6 |
| » Starters: Hooks Dauss vs Grover Lowdermilk | Fifth | 7 out |
| Tuesday, July 4 |
| » Defeated Indians (39-29), 6-2 | League Park II (3-3) | 35-35 | |
| » Starters: Bernie Boland vs Fred Beebe | Sixth | 7 out |
| » Lost to Indians (40-29), 6-3 | League Park II (3-4) | 35-36 | |
| » Starters: Bill James vs Stan Coveleski | Sixth | 7 out |
| Thursday, July 6 |
| » Defeated Athletics (17-48), 9-4 | Shibe Park (4-1) | 36-36 | |
| » Starters: Willie Mitchell vs Tom Sheehan | Sixth | 7½ out |
| Friday, July 7 |
| » Defeated Athletics (17-49), 9-2 | Shibe Park (5-1) | 37-36 | Won 2 |
| » Starters: Harry Coveleski vs Elmer Myers | Sixth | 7½ out |
| Saturday, July 8 |
| » Defeated Athletics (17-50), 3-2 | Shibe Park (6-1) | 38-36 | Won 3 |
| » Starters: Bill James vs Jack Nabors | Sixth | 6½ out |
| Tuesday, July 11 |
| » Defeated Senators (38-35), 4-3 | Griffith Stadium (1-4) | 39-36 | Won 4 |
| » Starters: Hooks Dauss vs Bert Gallia | Sixth | 6 out |
| » Lost to Senators (39-35), 3-1 | Griffith Stadium (1-5) | 39-37 | |
| » Starters: Bernie Boland vs Walter Johnson | Sixth | 6 out |
| Wednesday, July 12 |
| » Defeated Senators (39-36), 4-2 | Griffith Stadium (2-5) | 40-37 | |
| » Starters: Harry Coveleski vs Harry Harper | Sixth | 5 out |
| Thursday, July 13 |
| » Defeated Senators (39-37), 3-1 | Griffith Stadium (3-5) | 41-37 | Won 2 |
| » Starters: Bill James vs Joe Boehling | Fourth | 4½ out |
| Friday, July 14 |
| » Defeated Yankees (45-33), 6-2 | Polo Grounds V (1-1) | 42-37 | Won 3 |
| » Starters: Willie Mitchell vs Nick Cullop | Fifth | 4½ out |
| » Lost to Yankees (46-33), 4-3 | Polo Grounds V (1-2) | 42-38 | |
| » Starters: George Cunningham vs Allen Russell | Fifth | 4½ out |
| Saturday, July 15 |
| » Defeated Yankees (46-34), 9-7 | Polo Grounds V (2-2) | 43-38 | |
| » Starters: Hooks Dauss vs George Mogridge | Fifth | 3½ out |
| Monday, July 17 |
| » Lost to Yankees (47-34), 2-0 | Polo Grounds V (2-3) | 43-39 | |
| » Starters: Harry Coveleski vs Bob Shawkey | Sixth | 5½ out |
| » Lost to Yankees (48-34), 3-2 | Polo Grounds V (2-4) | 43-40 | Lost 2 |
| » Starters: Bill James vs Slim Love | Sixth | 5½ out |
| Tuesday, July 18 |
| » Defeated Yankees (48-35), 4-0 | Polo Grounds V (3-4) | 44-40 | |
| » Starters: Willie Mitchell vs Nick Cullop | Sixth | 4½ out |
| Future Tiger Johnny Hopp is born in Hastings, NE. |
| Wednesday, July 19 |
| » Lost to Red Sox (47-35), 4-2 | Fenway Park (0-4) | 44-41 | |
| » Starters: Hooks Dauss vs Carl Mays | Sixth | 6½ out |
| » Lost to Red Sox (48-35), 9-5 | Fenway Park (0-5) | 44-42 | Lost 2 |
| » Starters: George Cunningham vs Ernie Shore | Sixth | 6½ out |
| Thursday, July 20 |
| » Defeated Red Sox (48-36), 3-2 | Fenway Park (1-5) | 45-42 | |
| » Starters: Harry Coveleski vs Rube Foster | Sixth | 5½ out |
| Saturday, July 22 |
| » Defeated Red Sox (48-37), 4-3 | Fenway Park (2-5) | 46-42 | Won 2 |
| » Starters: Willie Mitchell vs Ernie Shore | Sixth | 6 out |
| » Lost to Red Sox (49-37), 1-0 | Fenway Park (2-6) | 46-43 | |
| » Starters: Bill James vs Dutch Leonard | Sixth | 6 out |
| Sunday, July 23 |
| » Lost to White Sox (47-40), 12-9 | Tiger Stadium (24-13) | 46-44 | Lost 2 |
| » Starters: Lefty Williams vs Bernie Boland | Fifth | 6½ out |
| Monday, July 24 |
| » Lost to White Sox (48-40), 3-2 | Tiger Stadium (24-14) | 46-45 | Lost 3 |
| » Starters: Mellie Wolfgang vs Harry Coveleski | Sixth | 7 out |
| Tuesday, July 25 |
| » Defeated Senators (47-41), 6-5 | Tiger Stadium (25-14) | 47-45 | |
| » Starters: Harry Harper vs Bill James | Sixth | 6 out |
| Wednesday, July 26 |
| » Defeated Senators (47-42), 6-5 | Tiger Stadium (26-14) | 48-45 | Won 2 |
| » Starters: Walter Johnson vs Willie Mitchell | Fifth | 5 out |
| Thursday, July 27 |
| » Defeated Senators (47-43), 7-4 | Tiger Stadium (27-14) | 49-45 | Won 3 |
| » Starters: Joe Boehling vs Bernie Boland | Fifth | 5 out |
| Friday, July 28 |
| » Defeated Senators (47-44), 3-0 | Tiger Stadium (28-14) | 50-45 | Won 4 |
| » Starters: Doc Ayers vs Jean Dubuc | Fourth | 5 out |
| Saturday, July 29 |
| » Defeated Red Sox (52-39), 10-8 | Tiger Stadium (29-14) | 51-45 | Won 5 |
| » Starters: Babe Ruth vs Harry Coveleski | Fifth | 3 out |
| » Defeated Red Sox (52-40), 7-3 | Tiger Stadium (30-14) | 52-45 | Won 6 |
| » Starters: Dutch Leonard vs Bill James | Fifth | 3 out |
| Sunday, July 30 |
| » Lost to Red Sox (53-40), 9-3 | Tiger Stadium (30-15) | 52-46 | |
| » Starters: Carl Mays vs Willie Mitchell | Fifth | 3½ out |
| Monday, July 31 |
| » Lost to Red Sox (54-40), 6-0 | Tiger Stadium (30-16) | 52-47 | Lost 2 |
| » Starters: Babe Ruth vs Harry Coveleski | Fifth | 4½ out |
| Future Tiger Billy Hitchcock is born in Inverness, AL. |
| Tuesday, August 1 |
| » Lost to Red Sox (55-40), 6-2 | Tiger Stadium (30-17) | 52-48 | Lost 3 |
| » Starters: Ernie Shore vs Bill James | Fifth | 5½ out |
| Wednesday, August 2 |
| » Lost to Red Sox (56-40), 5-2 | Tiger Stadium (30-18) | 52-49 | Lost 4 |
| » Starters: Rube Foster vs Bernie Boland | Fourth | 6½ out |
| Thursday, August 3 |
| » Defeated Yankees (53-45), 2-1 | Tiger Stadium (31-18) | 53-49 | |
| » Starters: Allen Russell vs Harry Coveleski | Fifth | 6 out |
| Friday, August 4 |
| » Defeated Yankees (53-46), 5-2 | Tiger Stadium (32-18) | 54-49 | Won 2 |
| » Starters: Bob Shawkey vs Jean Dubuc | Fifth | 5½ out |
| Saturday, August 5 |
| » Defeated Yankees (53-47), 3-2 | Tiger Stadium (33-18) | 55-49 | Won 3 |
| » Starters: George Mogridge vs Willie Mitchell | Fifth | 5½ out |
| Sunday, August 6 |
| » Lost to Yankees (54-47), 4-2 | Tiger Stadium (33-19) | 55-50 | |
| » Starters: Nick Cullop vs Hooks Dauss | Fifth | 5½ out |
| Monday, August 7 |
| » Defeated Athletics (19-79), 4-2 | Tiger Stadium (34-19) | 56-50 | |
| » Starters: Elmer Myers vs Harry Coveleski | Fifth | 5½ out |
| Tuesday, August 8 |
| » Defeated Athletics (19-80), 9-0 | Tiger Stadium (35-19) | 57-50 | Won 2 |
| » Starters: Jack Nabors vs Bernie Boland | Fifth | 4½ out |
| Wednesday, August 9 |
| » Lost to Athletics (20-80), 7-1 | Tiger Stadium (35-20) | 57-51 | |
| » Starters: Bullet Joe Bush vs Jean Dubuc | Fifth | 5 out |
| Thursday, August 10 |
| » Defeated Athletics (20-81), 10-4 | Tiger Stadium (36-20) | 58-51 | |
| » Starters: Marsh Williams vs Willie Mitchell | Fourth | 5 out |
| Friday, August 11 |
| » Defeated White Sox (61-48), 2-0 | Comiskey Park I (2-7) | 59-51 | Won 2 |
| » Starters: Harry Coveleski vs Mellie Wolfgang | Fourth | 4½ out |
| Saturday, August 12 |
| » Lost to White Sox (62-48), 3-0 | Comiskey Park I (2-8) | 59-52 | |
| » Starters: Hooks Dauss vs Red Faber | Fifth | 5½ out |
| Sunday, August 13 |
| » Defeated White Sox (62-49), 9-4 | Comiskey Park I (3-8) | 60-52 | |
| » Starters: Bill James vs Jim Scott | Fourth | 5 out |
| Monday, August 14 |
| » Lost to Indians (62-48), 3-2 | League Park II (3-5) | 60-53 | |
| » Starters: Jean Dubuc vs Jim Bagby | Fifth | 5 out |
| Thursday, August 17 |
| » Defeated Senators (52-57), 11-6 | Griffith Stadium (4-5) | 61-53 | |
| » Starters: Hooks Dauss vs Harry Harper | Fourth | 5 out |
| » Defeated Senators (52-58), 8-4 | Griffith Stadium (5-5) | 62-53 | Won 2 |
| » Starters: Hooks Dauss vs Bert Gallia | Fourth | 5 out |
| Friday, August 18 |
| » Lost to Senators (53-58), 2-1 | Griffith Stadium (5-6) | 62-54 | |
| » Starters: Jean Dubuc vs Doc Ayers | Sixth | 5 out |
| Saturday, August 19 |
| » Defeated Athletics (23-86), 6-2 | Shibe Park (7-1) | 63-54 | |
| » Starters: Harry Coveleski vs Jing Johnson | Fourth | 5 out |
| Monday, August 21 |
| » Defeated Athletics (23-87), 7-1 | Shibe Park (8-1) | 64-54 | Won 2 |
| » Starters: Hooks Dauss vs Elmer Myers | Third | 5 out |
| Tuesday, August 22 |
| » Lost to Athletics (24-87), 1-0 | Shibe Park (8-2) | 64-55 | |
| » Starters: Bill James vs Bullet Joe Bush | Fourth | 6 out |
| Wednesday, August 23 |
| » Defeated Athletics (24-88), 10-3 | Shibe Park (9-2) | 65-55 | |
| » Starters: George Cunningham vs Marsh Williams | Fourth | 6 out |
| Thursday, August 24 |
| » Lost to Red Sox (70-47), 3-0 | Fenway Park (2-7) | 65-56 | |
| » Starters: Harry Coveleski vs Babe Ruth | Fourth | 7 out |
| Friday, August 25 |
| » Defeated Red Sox (70-48), 2-1 | Fenway Park (3-7) | 66-56 | |
| » Starters: Hooks Dauss vs Ernie Shore | Second | 6 out |
| Saturday, August 26 |
| » Defeated Red Sox (70-49), 2-1 | Fenway Park (4-7) | 67-56 | Won 2 |
| » Starters: Bill James vs Carl Mays | Second | 5 out |
| Tuesday, August 29 |
| » Defeated Yankees (65-57), 9-1 | Polo Grounds V (4-4) | 68-56 | Won 3 |
| » Starters: Harry Coveleski vs Nick Cullop | Second | 3 out |
| » Defeated Yankees (65-58), 4-1 | Polo Grounds V (5-4) | 69-56 | Won 4 |
| » Starters: Hooks Dauss vs George Mogridge | Second | 3 out |
| Wednesday, August 30 |
| » Lost to Yankees (66-58), 5-2 | Polo Grounds V (5-5) | 69-57 | |
| » Starters: Bill James vs Bob Shawkey | Second | 4 out |
| Thursday, August 31 |
| » Defeated Yankees (66-59), 7-3 | Polo Grounds V (6-5) | 70-57 | |
| » Starters: Willie Mitchell vs Allen Russell | Second | 3 out |
| Saturday, September 2 |
| » Defeated White Sox (69-58), 2-1 | Tiger Stadium (37-20) | 71-57 | Won 2 |
| » Starters: Reb Russell vs Harry Coveleski | Second | 2½ out |
| Sunday, September 3 |
| » Defeated Indians (68-61), 5-3 | Tiger Stadium (38-20) | 72-57 | Won 3 |
| » Starters: Jim Bagby vs Hooks Dauss | Second | 2 out |
| Monday, September 4 |
| » Defeated Indians (68-62), 11-8 | Tiger Stadium (39-20) | 73-57 | Won 4 |
| » Starters: Stan Coveleski vs Bernie Boland | Second | 2 out |
| » Defeated Indians (68-63), 7-5 | Tiger Stadium (40-20) | 74-57 | Won 5 |
| » Starters: Guy Morton vs Willie Mitchell | Second | 2 out |
| Wednesday, September 6 |
| » Defeated Browns (69-63), 4-3 | Tiger Stadium (41-20) | 75-57 | Won 6 |
| » Starters: Carl Weilman vs Harry Coveleski | Second | 1 out |
| Thursday, September 7 |
| » Lost to Browns (70-63), 6-5 | Tiger Stadium (41-21) | 75-58 | |
| » Starters: Dave Davenport vs Hooks Dauss | Second | 2 out |
| Friday, September 8 |
| » Defeated Browns (70-64), 3-0 | Tiger Stadium (42-21) | 76-58 | |
| » Starters: Bob Groom vs Willie Mitchell | Second | 1½ out |
| Saturday, September 9 |
| » Defeated Browns (70-65), 12-8 | Tiger Stadium (43-21) | 77-58 | Won 2 |
| » Starters: Carl Weilman vs Harry Coveleski | Second | 1 out |
| Sunday, September 10 |
| » Lost to Indians (69-67), 8-2 | League Park II (3-6) | 77-59 | |
| » Starters: Bill James vs Guy Morton | Second | 1½ out |
| Monday, September 11 |
| » Defeated Indians (69-68), 9-1 | League Park II (4-6) | 78-59 | |
| » Starters: Hooks Dauss vs Joe Boehling | Second | 1½ out |
| » Major-league debuts: Ken Penner (Indians) |
| Tuesday, September 12 |
| » Defeated Indians (69-69), 10-2 | League Park II (5-6) | 79-59 | Won 2 |
| » Starters: Howard Ehmke vs Stan Coveleski | Second | 1½ out |
| » Major-league debuts: Hank DeBerry (Indians) |
| Future Tiger Charlie Keller is born in Middletown, MD. |
| Wednesday, September 13 |
| » Defeated Yankees (71-65), 4-1 | Tiger Stadium (44-21) | 80-59 | Won 3 |
| » Starters: Bob Shawkey vs Harry Coveleski | Second | 2 out |
| Thursday, September 14 |
| » Lost to Yankees (72-65), 4-2 | Tiger Stadium (44-22) | 80-60 | |
| » Starters: Urban Shocker vs Willie Mitchell | Second | 2 out |
| Friday, September 15 |
| » Defeated Yankees (72-66), 4-2 | Tiger Stadium (45-22) | 81-60 | |
| » Starters: George Mogridge vs Hooks Dauss | Second | 2 out |
| Saturday, September 16 |
| » Defeated Athletics (30-107), 4-3 | Tiger Stadium (46-22) | 82-60 | Won 2 |
| » Starters: Jing Johnson vs Howard Ehmke | First | -- |
| Sunday, September 17 |
| » Defeated Athletics (30-108), 6-5 | Tiger Stadium (47-22) | 83-60 | Won 3 |
| » Starters: Bullet Joe Bush vs Harry Coveleski | First | -- |
| Monday, September 18 |
| » Lost to Athletics (31-108), 2-0 | Tiger Stadium (47-23) | 83-61 | |
| » Starters: Elmer Myers vs Willie Mitchell | Second | 2 out |
| Tuesday, September 19 |
| » Lost to Red Sox (82-59), 3-1 | Tiger Stadium (47-24) | 83-62 | Lost 2 |
| » Starters: Carl Mays vs Hooks Dauss | Second | 2 out |
| Wednesday, September 20 |
| » Lost to Red Sox (83-59), 4-3 | Tiger Stadium (47-25) | 83-63 | Lost 3 |
| » Starters: Dutch Leonard vs Howard Ehmke | Third | 2 out |
| Thursday, September 21 |
| » Lost to Red Sox (84-59), 10-2 | Tiger Stadium (47-26) | 83-64 | Lost 4 |
| » Starters: Babe Ruth vs Harry Coveleski | Third | 3 out |
| Friday, September 22 |
| » Defeated Senators (71-72), 6-5 | Tiger Stadium (48-26) | 84-64 | |
| » Starters: Claude Thomas vs Willie Mitchell | Third | 3 out |
| Saturday, September 23 |
| » Lost to Senators (72-72), 6-3 | Tiger Stadium (48-27) | 84-65 | |
| » Starters: Bert Gallia vs Bill James | Third | 4 out |
| » Major-league debuts: Deacon Jones (Tigers) |
| Sunday, September 24 |
| » Defeated Senators (72-73), 6-5 | Tiger Stadium (49-27) | 85-65 | |
| » Starters: Walter Johnson vs Howard Ehmke | Third | 3 out |
| Monday, September 25 |
| » Lost to Senators (73-73), 8-5 | Tiger Stadium (49-28) | 85-66 | |
| » Starters: Doc Ayers vs Hooks Dauss | Third | 4 out |
| Friday, September 29 |
| » Defeated Browns (78-74), 4-1 | Sportsman's Park III (5-4) | 86-66 | |
| » Starters: Willie Mitchell vs Carl Weilman | Third | 4 out |
| Saturday, September 30 |
| » Defeated Browns (78-75), 10-7 | Sportsman's Park III (6-4) | 87-66 | Won 2 |
| » Starters: Bernie Boland vs Ernie Koob | Third | 4 out |
| Sunday, October 1 |
| » Lost to Browns (79-75), 6-3 | Sportsman's Park III (6-5) | 87-67 | |
| » Starters: Bill James vs Eddie Plank | Third | 4½ out |
| Tuesday, October 3 |
| » Major-league debuts: Axel Lindstrom (Athletics) |
Game information provided by Retrosheet (www.retrosheet.org) |