| Monday, January 24 |
| Future Red Sox Clem Dreisewerd is born in Old Monroe, MO. |
| Wednesday, February 9 |
| Future Red Sox Tex Hughson is born in Buda, TX. |
| Saturday, March 18 |
| Future Red Sox Eddie Lake is born in Antioch, CA. |
| Tuesday, April 4 |
| Future Red Sox Mickey Owen is born in Nixa, MO. |
| Wednesday, April 12 |
| » Defeated Athletics (0-1), 2-1 | Fenway Park (1-0) | 1-0 | |
| » Starters: Jack Nabors vs Babe Ruth | First | -- |
| Thursday, April 13 |
| » Defeated Athletics (0-2), 8-2 | Fenway Park (2-0) | 2-0 | Won 2 |
| » Starters: Carl Ray vs Ernie Shore | First | -- |
| Saturday, April 15 |
| » Defeated Athletics (0-3), 2-1 | Fenway Park (3-0) | 3-0 | Won 3 |
| » Starters: Bullet Joe Bush vs Rube Foster | First | -- |
| Monday, April 17 |
| » Defeated Senators (1-2), 5-1 | Fenway Park (4-0) | 4-0 | Won 4 |
| » Starters: Walter Johnson vs Babe Ruth | First | -- |
| Tuesday, April 18 |
| » Lost to Senators (2-2), 4-2 | Fenway Park (4-1) | 4-1 | |
| » Starters: Harry Harper vs Ernie Shore | First | -- |
| Wednesday, April 19 |
| » Lost to Senators (3-2), 3-2 | Fenway Park (4-2) | 4-2 | Lost 2 |
| » Starters: Joe Boehling vs Rube Foster | Second | 1½ out |
| » Defeated Senators (3-3), 2-0 | Fenway Park (5-2) | 5-2 | |
| » Starters: Bert Gallia vs Dutch Leonard | Second | 1½ out |
| Thursday, April 20 |
| » Defeated Athletics (0-6), 7-1 | Shibe Park (1-0) | 6-2 | Won 2 |
| » Starters: Babe Ruth vs Bullet Joe Bush | First | -- |
| Friday, April 21 |
| » Lost to Athletics (1-6), 3-1 | Shibe Park (1-1) | 6-3 | |
| » Starters: Herb Pennock vs Elmer Myers | First | -- |
| Saturday, April 22 |
| » Lost to Athletics (2-6), 6-2 | Shibe Park (1-2) | 6-4 | Lost 2 |
| » Starters: Rube Foster vs Jack Nabors | Third | 1½ out |
| Monday, April 24 |
| » Defeated Athletics (2-7), 4-0 | Shibe Park (2-2) | 7-4 | |
| » Starters: Dutch Leonard vs Cap Crowell | First | -- |
| Tuesday, April 25 |
| » Defeated Yankees (5-4), 4-3 | Polo Grounds V (1-0) | 8-4 | Won 2 |
| » Starters: Babe Ruth vs Ray Caldwell | First | -- |
| Wednesday, April 26 |
| » Lost to Yankees (6-4), 9-0 | Polo Grounds V (1-1) | 8-5 | |
| » Starters: Marty McHale vs Cliff Markle | First | -- |
| Friday, April 28 |
| » Defeated Yankees (6-5), 3-2 | Polo Grounds V (2-1) | 9-5 | |
| » Starters: Dutch Leonard vs Ray Keating | First | -- |
| Saturday, April 29 |
| » Lost to Senators (8-6), 4-0 | Griffith Stadium (0-1) | 9-6 | |
| » Starters: Rube Foster vs Walter Johnson | Second | ½ out |
| Monday, May 1 |
| » Lost to Senators (9-6), 5-3 | Griffith Stadium (0-2) | 9-7 | Lost 2 |
| » Starters: Babe Ruth vs Harry Harper | Second | ½ out |
| Tuesday, May 2 |
| » Lost to Senators (10-6), 7-4 | Griffith Stadium (0-3) | 9-8 | Lost 3 |
| » Starters: Ernie Shore vs Joe Boehling | Fourth | 1½ out |
| Thursday, May 4 |
| » Defeated Yankees (8-8), 3-0 | Fenway Park (6-2) | 10-8 | |
| » Starters: Ray Caldwell vs Dutch Leonard | Third | 1½ out |
| Friday, May 5 |
| » Lost to Yankees (9-8), 8-4 | Fenway Park (6-3) | 10-9 | |
| » Starters: Ray Fisher vs Babe Ruth | Fourth | 2 out |
| Saturday, May 6 |
| » Lost to Yankees (10-8), 5-4 | Fenway Park (6-4) | 10-10 | Lost 2 |
| » Starters: Cliff Markle vs Rube Foster | Fourth | 3 out |
| Monday, May 8 |
| » Lost to Yankees (11-8), 4-0 | Fenway Park (6-5) | 10-11 | Lost 3 |
| » Starters: George Mogridge vs Vean Gregg | Third | 4½ out |
| Tuesday, May 9 |
| » Defeated Indians (15-8), 5-1 | Fenway Park (7-5) | 11-11 | |
| » Starters: Stan Coveleski vs Dutch Leonard | Third | 3½ out |
| Wednesday, May 10 |
| » Lost to Indians (16-8), 6-2 | Fenway Park (7-6) | 11-12 | |
| » Starters: Guy Morton vs Babe Ruth | Sixth | 4½ out |
| Thursday, May 11 |
| » Defeated Indians (16-9), 6-5 | Fenway Park (8-6) | 12-12 | |
| » Starters: Willie Mitchell vs Ernie Shore | Fourth | 3½ out |
| Friday, May 12 |
| » Lost to Indians (17-9), 3-1 | Fenway Park (8-7) | 12-13 | |
| » Starters: Fritz Coumbe vs Herb Pennock | Fifth | 4½ out |
| Saturday, May 13 |
| » Defeated White Sox (12-16), 3-2 | Fenway Park (9-7) | 13-13 | |
| » Starters: Eddie Cicotte vs Dutch Leonard | Fourth | 4½ out |
| Thursday, May 18 |
| » Lost to Browns (10-16), 7-1 | Fenway Park (9-8) | 13-14 | |
| » Starters: Carl Weilman vs Rube Foster | Fourth | 6 out |
| Friday, May 19 |
| » Lost to Browns (11-16), 5-1 | Fenway Park (9-9) | 13-15 | Lost 2 |
| » Starters: Bob Groom vs Dutch Leonard | Fourth | 7 out |
| Saturday, May 20 |
| » Defeated Browns (11-17), 3-1 | Fenway Park (10-9) | 14-15 | |
| » Starters: Dave Davenport vs Babe Ruth | Fourth | 6 out |
| Future Red Sox Joe Wood is born in Shohola, PA. |
| Monday, May 22 |
| » Defeated Tigers (13-18), 2-1 | Fenway Park (11-9) | 15-15 | Won 2 |
| » Starters: Hooks Dauss vs Vean Gregg | Fourth | 5 out |
| Wednesday, May 24 |
| » Defeated Tigers (13-19), 4-0 | Fenway Park (12-9) | 16-15 | Won 3 |
| » Starters: Jean Dubuc vs Babe Ruth | Fourth | 4½ out |
| Thursday, May 25 |
| » Defeated Tigers (13-20), 5-2 | Fenway Park (13-9) | 17-15 | Won 4 |
| » Starters: George Cunningham vs Ernie Shore | Fourth | 4 out |
| Friday, May 26 |
| » Lost to Yankees (17-13), 2-1 | Polo Grounds V (2-2) | 17-16 | |
| » Starters: Dutch Leonard vs Ray Fisher | Fourth | 5½ out |
| » Lost to Yankees (18-13), 6-5 | Polo Grounds V (2-3) | 17-17 | Lost 2 |
| » Starters: Vean Gregg vs Allen Russell | Fourth | 5½ out |
| Saturday, May 27 |
| » Lost to Yankees (19-13), 4-2 | Polo Grounds V (2-4) | 17-18 | Lost 3 |
| » Starters: Babe Ruth vs Ray Keating | Fourth | 6½ out |
| Monday, May 29 |
| » Defeated Yankees (19-14), 3-0 | Polo Grounds V (3-4) | 18-18 | |
| » Starters: Carl Mays vs Ray Caldwell | Fourth | 6 out |
| Tuesday, May 30 |
| » Defeated Senators (24-13), 4-3 | Fenway Park (14-9) | 19-18 | Won 2 |
| » Starters: Harry Harper vs Ernie Shore | Fourth | 4 out |
| » Defeated Senators (24-14), 8-2 | Fenway Park (15-9) | 20-18 | Won 3 |
| » Starters: Joe Boehling vs Dutch Leonard | Fourth | 4 out |
| Wednesday, May 31 |
| » Defeated Senators (24-15), 10-1 | Fenway Park (16-9) | 21-18 | Won 4 |
| » Starters: Bert Gallia vs Vean Gregg | Third | 3 out |
| Thursday, June 1 |
| » Defeated Senators (24-16), 1-0 | Fenway Park (17-9) | 22-18 | Won 5 |
| » Starters: Walter Johnson vs Babe Ruth | Fourth | 2½ out |
| Saturday, June 3 |
| » Lost to Indians (26-17), 11-2 | League Park II (0-1) | 22-19 | |
| » Starters: Dutch Leonard vs Stan Coveleski | Fourth | 3 out |
| Sunday, June 4 |
| » Lost to Indians (27-17), 9-3 | League Park II (0-2) | 22-20 | Lost 2 |
| » Starters: Carl Mays vs Jim Bagby | Fourth | 4 out |
| Monday, June 5 |
| » Defeated Indians (27-18), 5-0 | League Park II (1-2) | 23-20 | |
| » Starters: Babe Ruth vs Fritz Coumbe | Fourth | 3 out |
| Future Red Sox Eddie Joost is born in San Francisco, CA. |
| Tuesday, June 6 |
| » Lost to Tigers (22-23), 3-0 | Tiger Stadium (0-1) | 23-21 | |
| » Starters: Vean Gregg vs Hooks Dauss | Fourth | 3½ out |
| Friday, June 9 |
| » Lost to Tigers (23-23), 6-5 | Tiger Stadium (0-2) | 23-22 | Lost 2 |
| » Starters: Babe Ruth vs Jean Dubuc | Fourth | 3½ out |
| Saturday, June 10 |
| » Defeated Browns (20-26), 4-2 | Sportsman's Park III (1-0) | 24-22 | |
| » Starters: Dutch Leonard vs Bob Groom | Fourth | 3½ out |
| Monday, June 12 |
| » Lost to Browns (21-26), 4-3 | Sportsman's Park III (1-1) | 24-23 | |
| » Starters: Vean Gregg vs Jim Park | Fifth | 5 out |
| Tuesday, June 13 |
| » Defeated Browns (21-27), 5-3 | Sportsman's Park III (2-1) | 25-23 | |
| » Starters: Babe Ruth vs Dave Davenport | Fourth | 5 out |
| Wednesday, June 14 |
| » Lost to Browns (22-27), 8-5 | Sportsman's Park III (2-2) | 25-24 | |
| » Starters: Carl Mays vs Carl Weilman | Fifth | 5½ out |
| Thursday, June 15 |
| » Defeated White Sox (23-25), 2-1 | Comiskey Park I (1-0) | 26-24 | |
| » Starters: Dutch Leonard vs Reb Russell | Fifth | 5½ out |
| Friday, June 16 |
| » Lost to White Sox (24-25), 7-4 | Comiskey Park I (1-1) | 26-25 | |
| » Starters: Vean Gregg vs Lefty Williams | Fifth | 6 out |
| Saturday, June 17 |
| » Lost to White Sox (25-25), 5-0 | Comiskey Park I (1-2) | 26-26 | Lost 2 |
| » Starters: Babe Ruth vs Joe Benz | Sixth | 6 out |
| Sunday, June 18 |
| » Defeated White Sox (25-26), 3-1 | Comiskey Park I (2-2) | 27-26 | |
| » Starters: Ernie Shore vs Jim Scott | Fifth | 5 out |
| Tuesday, June 20 |
| » Lost to Yankees (29-23), 4-1 | Fenway Park (17-10) | 27-27 | |
| » Starters: Ray Keating vs Dutch Leonard | Sixth | 4½ out |
| Wednesday, June 21 |
| » Defeated Yankees (29-24), 2-0 | Fenway Park (18-10) | 28-27 | |
| » Starters: Bob Shawkey vs Rube Foster | Fourth | 3½ out |
| Thursday, June 22 |
| » Defeated Yankees (29-25), 1-0 | Fenway Park (19-10) | 29-27 | Won 2 |
| » Starters: Ray Fisher vs Babe Ruth | Fifth | 3½ out |
| Friday, June 23 |
| » Defeated Athletics (16-37), 1-0 | Fenway Park (20-10) | 30-27 | Won 3 |
| » Starters: Tom Sheehan vs Ernie Shore | Fifth | 3 out |
| Saturday, June 24 |
| » Defeated Athletics (16-38), 3-2 | Fenway Park (21-10) | 31-27 | Won 4 |
| » Starters: Jack Nabors vs Dutch Leonard | Fourth | 2½ out |
| » Defeated Athletics (16-39), 7-3 | Fenway Park (22-10) | 32-27 | Won 5 |
| » Starters: Bullet Joe Bush vs Carl Mays | Fourth | 2½ out |
| Monday, June 26 |
| » Lost to Athletics (17-39), 8-5 | Fenway Park (22-11) | 32-28 | |
| » Starters: Weldon Wyckoff vs Rube Foster | Fourth | 3 out |
| Tuesday, June 27 |
| » Defeated Athletics (17-40), 7-2 | Fenway Park (23-11) | 33-28 | |
| » Starters: Jing Johnson vs Babe Ruth | Third | 2 out |
| Wednesday, June 28 |
| » Lost to Senators (33-29), 6-2 | Griffith Stadium (0-4) | 33-29 | |
| » Starters: Ernie Shore vs Walter Johnson | Third | 2½ out |
| Thursday, June 29 |
| » Lost to Senators (34-29), 3-0 | Griffith Stadium (0-5) | 33-30 | Lost 2 |
| » Starters: Dutch Leonard vs Harry Harper | Fifth | 3½ out |
| Friday, June 30 |
| » Defeated Senators (34-30), 6-1 | Griffith Stadium (1-5) | 34-30 | |
| » Starters: Carl Mays vs Bert Gallia | Fourth | 3½ out |
| Saturday, July 1 |
| » Lost to Senators (35-30), 4-2 | Griffith Stadium (1-6) | 34-31 | |
| » Starters: Babe Ruth vs Joe Boehling | Fifth | 4½ out |
| Monday, July 3 |
| » Defeated Athletics (17-45), 6-4 | Shibe Park (3-2) | 35-31 | |
| » Starters: Ernie Shore vs Jack Nabors | Fourth | 4½ out |
| Tuesday, July 4 |
| » Defeated Athletics (17-46), 11-2 | Shibe Park (4-2) | 36-31 | Won 2 |
| » Starters: Dutch Leonard vs George Hesselbacher | Fourth | 3½ out |
| » Defeated Athletics (17-47), 5-2 | Shibe Park (5-2) | 37-31 | Won 3 |
| » Starters: Carl Mays vs Bullet Joe Bush | Fourth | 3½ out |
| Thursday, July 6 |
| » Defeated Indians (40-30), 6-5 | Fenway Park (24-11) | 38-31 | Won 4 |
| » Starters: Ed Klepfer vs Rube Foster | Third | 4 out |
| Friday, July 7 |
| » Defeated Indians (40-31), 2-1 | Fenway Park (25-11) | 39-31 | Won 5 |
| » Starters: Fred Beebe vs Babe Ruth | Third | 4 out |
| Saturday, July 8 |
| » Lost to Indians (41-31), 5-1 | Fenway Park (25-12) | 39-32 | |
| » Starters: Stan Coveleski vs Ernie Shore | Third | 4 out |
| Monday, July 10 |
| » Lost to White Sox (39-32), 4-0 | Fenway Park (25-13) | 39-33 | Lost 2 |
| » Starters: Lefty Williams vs Dutch Leonard | Fourth | 4½ out |
| » Lost to White Sox (40-32), 3-0 | Fenway Park (25-14) | 39-34 | Lost 3 |
| » Starters: Reb Russell vs Carl Mays | Fourth | 4½ out |
| Tuesday, July 11 |
| » Defeated White Sox (40-33), 5-3 | Fenway Park (26-14) | 40-34 | |
| » Starters: Dave Danforth vs Babe Ruth | Third | 3½ out |
| » Defeated White Sox (40-34), 3-1 | Fenway Park (27-14) | 41-34 | Won 2 |
| » Starters: Mellie Wolfgang vs Babe Ruth | Third | 3½ out |
| Wednesday, July 12 |
| » Defeated White Sox (40-35), 2-1 | Fenway Park (28-14) | 42-34 | Won 3 |
| » Starters: Reb Russell vs Ernie Shore | Third | 2 out |
| » Defeated White Sox (40-36), 3-1 | Fenway Park (29-14) | 43-34 | Won 4 |
| » Starters: Lefty Williams vs Dutch Leonard | Third | 2 out |
| Friday, July 14 |
| » Tied Browns, 0-0 | Fenway Park (29-14) | 43-34 | |
| » Starters: Ernie Koob vs Carl Mays | Third | 2 out |
| Saturday, July 15 |
| » Lost to Browns (36-43), 2-1 | Fenway Park (29-15) | 43-35 | |
| » Starters: Earl Hamilton vs Rube Foster | Third | 1½ out |
| » Defeated Browns (36-44), 17-4 | Fenway Park (30-15) | 44-35 | |
| » Starters: Dave Davenport vs Babe Ruth | Third | 1½ out |
| Monday, July 17 |
| » Defeated Browns (36-45), 3-2 | Fenway Park (31-15) | 45-35 | Won 2 |
| » Starters: Eddie Plank vs Dutch Leonard | Second | 2 out |
| Tuesday, July 18 |
| » Defeated Browns (36-46), 4-3 | Fenway Park (32-15) | 46-35 | Won 3 |
| » Starters: Carl Weilman vs Babe Ruth | Second | 1 out |
| Wednesday, July 19 |
| » Defeated Tigers (44-41), 4-2 | Fenway Park (33-15) | 47-35 | Won 4 |
| » Starters: Hooks Dauss vs Carl Mays | Second | 1 out |
| » Defeated Tigers (44-42), 9-5 | Fenway Park (34-15) | 48-35 | Won 5 |
| » Starters: George Cunningham vs Ernie Shore | Second | 1 out |
| Thursday, July 20 |
| » Lost to Tigers (45-42), 3-2 | Fenway Park (34-16) | 48-36 | |
| » Starters: Harry Coveleski vs Rube Foster | Second | 1 out |
| Saturday, July 22 |
| » Lost to Tigers (46-42), 4-3 | Fenway Park (34-17) | 48-37 | Lost 2 |
| » Starters: Willie Mitchell vs Ernie Shore | Second | 1½ out |
| » Defeated Tigers (46-43), 1-0 | Fenway Park (35-17) | 49-37 | |
| » Starters: Bill James vs Dutch Leonard | Second | 1½ out |
| Tuesday, July 25 |
| » Lost to Indians (50-39), 5-4 | League Park II (1-3) | 49-38 | |
| » Starters: Babe Ruth vs Jim Bagby | Second | 1½ out |
| Wednesday, July 26 |
| » Defeated Indians (50-40), 3-2 | League Park II (2-3) | 50-38 | |
| » Starters: Carl Mays vs Fred Beebe | Second | ½ out |
| Thursday, July 27 |
| » Defeated Indians (50-41), 7-6 | League Park II (3-3) | 51-38 | Won 2 |
| » Starters: Rube Foster vs Stan Coveleski | Second | ½ out |
| Friday, July 28 |
| » Defeated Indians (50-42), 3-2 | League Park II (4-3) | 52-38 | Won 3 |
| » Starters: Ernie Shore vs Al Gould | Second | ½ out |
| Saturday, July 29 |
| » Lost to Tigers (51-45), 10-8 | Tiger Stadium (0-3) | 52-39 | |
| » Starters: Babe Ruth vs Harry Coveleski | Second | ½ out |
| » Lost to Tigers (52-45), 7-3 | Tiger Stadium (0-4) | 52-40 | Lost 2 |
| » Starters: Dutch Leonard vs Bill James | Second | ½ out |
| Sunday, July 30 |
| » Defeated Tigers (52-46), 9-3 | Tiger Stadium (1-4) | 53-40 | |
| » Starters: Carl Mays vs Willie Mitchell | First | -- |
| Monday, July 31 |
| » Defeated Tigers (52-47), 6-0 | Tiger Stadium (2-4) | 54-40 | Won 2 |
| » Starters: Babe Ruth vs Harry Coveleski | First | -- |
| Future Red Sox Billy Hitchcock is born in Inverness, AL. |
| Tuesday, August 1 |
| » Defeated Tigers (52-48), 6-2 | Tiger Stadium (3-4) | 55-40 | Won 3 |
| » Starters: Ernie Shore vs Bill James | First | -- |
| Wednesday, August 2 |
| » Defeated Tigers (52-49), 5-2 | Tiger Stadium (4-4) | 56-40 | Won 4 |
| » Starters: Rube Foster vs Bernie Boland | First | -- |
| Thursday, August 3 |
| » Lost to Browns (50-49), 3-2 | Sportsman's Park III (2-3) | 56-41 | |
| » Starters: Dutch Leonard vs Ernie Koob | Second | 1½ out |
| Friday, August 4 |
| » Lost to Browns (51-49), 6-1 | Sportsman's Park III (2-4) | 56-42 | Lost 2 |
| » Starters: Babe Ruth vs Eddie Plank | Second | 2 out |
| Saturday, August 5 |
| » Defeated Browns (51-50), 4-1 | Sportsman's Park III (3-4) | 57-42 | |
| » Starters: Ernie Shore vs Earl Hamilton | Second | 1½ out |
| » Lost to Browns (52-50), 6-3 | Sportsman's Park III (3-5) | 57-43 | |
| » Starters: Carl Mays vs Dave Davenport | Second | 1½ out |
| Sunday, August 6 |
| » Defeated Browns (52-51), 1-0 | Sportsman's Park III (4-5) | 58-43 | |
| » Starters: Rube Foster vs Ernie Koob | Second | 1½ out |
| Monday, August 7 |
| » Lost to White Sox (61-44), 7-1 | Comiskey Park I (2-3) | 58-44 | |
| » Starters: Dutch Leonard vs Reb Russell | Second | 1½ out |
| Tuesday, August 8 |
| » Defeated White Sox (61-45), 6-4 | Comiskey Park I (3-3) | 59-44 | |
| » Starters: Carl Mays vs Red Faber | Second | 1½ out |
| Wednesday, August 9 |
| » Defeated White Sox (61-46), 3-1 | Comiskey Park I (4-3) | 60-44 | Won 2 |
| » Starters: Ernie Shore vs Jim Scott | First | -- |
| Thursday, August 10 |
| » Defeated White Sox (61-47), 11-5 | Comiskey Park I (5-3) | 61-44 | Won 3 |
| » Starters: Rube Foster vs Reb Russell | First | -- |
| Saturday, August 12 |
| » Defeated Senators (51-55), 2-1 | Fenway Park (36-17) | 62-44 | Won 4 |
| » Starters: Harry Harper vs Babe Ruth | First | -- |
| Monday, August 14 |
| » Lost to Senators (52-55), 2-1 | Fenway Park (36-18) | 62-45 | |
| » Starters: Bert Gallia vs Carl Mays | First | -- |
| Tuesday, August 15 |
| » Defeated Senators (52-56), 1-0 | Fenway Park (37-18) | 63-45 | |
| » Starters: Walter Johnson vs Babe Ruth | First | -- |
| Wednesday, August 16 |
| » Defeated White Sox (62-50), 5-4 | Fenway Park (38-18) | 64-45 | Won 2 |
| » Starters: Red Faber vs Dutch Leonard | First | -- |
| » Defeated White Sox (62-51), 2-1 | Fenway Park (39-18) | 65-45 | Won 3 |
| » Starters: Lefty Williams vs Rube Foster | First | -- |
| Thursday, August 17 |
| » Lost to White Sox (63-51), 7-0 | Fenway Park (39-19) | 65-46 | |
| » Starters: Reb Russell vs Carl Mays | First | -- |
| Friday, August 18 |
| » Lost to White Sox (64-51), 11-6 | Fenway Park (39-20) | 65-47 | Lost 2 |
| » Starters: Lefty Williams vs Dutch Leonard | First | -- |
| Saturday, August 19 |
| » Defeated Indians (62-52), 2-1 | Fenway Park (40-20) | 66-47 | |
| » Starters: Joe Boehling vs Babe Ruth | First | -- |
| Monday, August 21 |
| » Defeated Indians (62-53), 4-0 | Fenway Park (41-20) | 67-47 | Won 2 |
| » Starters: Guy Morton vs Ernie Shore | First | -- |
| Tuesday, August 22 |
| » Defeated Indians (62-54), 3-0 | Fenway Park (42-20) | 68-47 | Won 3 |
| » Starters: Jim Bagby vs Carl Mays | First | -- |
| Wednesday, August 23 |
| » Defeated Indians (62-55), 7-3 | Fenway Park (43-20) | 69-47 | Won 4 |
| » Starters: Joe Boehling vs Dutch Leonard | First | -- |
| Thursday, August 24 |
| » Defeated Tigers (65-56), 3-0 | Fenway Park (44-20) | 70-47 | Won 5 |
| » Starters: Harry Coveleski vs Babe Ruth | First | -- |
| Friday, August 25 |
| » Lost to Tigers (66-56), 2-1 | Fenway Park (44-21) | 70-48 | |
| » Starters: Hooks Dauss vs Ernie Shore | First | -- |
| Saturday, August 26 |
| » Lost to Tigers (67-56), 2-1 | Fenway Park (44-22) | 70-49 | Lost 2 |
| » Starters: Bill James vs Carl Mays | First | -- |
| Tuesday, August 29 |
| » Lost to Browns (67-57), 5-3 | Fenway Park (44-23) | 70-50 | Lost 3 |
| » Starters: Dave Davenport vs Babe Ruth | First | -- |
| » Lost to Browns (68-57), 8-2 | Fenway Park (44-24) | 70-51 | Lost 4 |
| » Starters: Bob Groom vs Ernie Shore | First | -- |
| Wednesday, August 30 |
| » Defeated Browns (68-58), 4-0 | Fenway Park (45-24) | 71-51 | |
| » Starters: Carl Weilman vs Dutch Leonard | First | -- |
| Thursday, August 31 |
| » Lost to Browns (69-58), 2-1 | Fenway Park (45-25) | 71-52 | |
| » Starters: Ernie Koob vs Babe Ruth | First | -- |
| Friday, September 1 |
| » Lost to Yankees (67-59), 7-3 | Polo Grounds V (3-5) | 71-53 | Lost 2 |
| » Starters: Carl Mays vs Urban Shocker | First | -- |
| Saturday, September 2 |
| » Defeated Yankees (67-60), 5-3 | Polo Grounds V (4-5) | 72-53 | |
| » Starters: Rube Foster vs George Mogridge | First | -- |
| Monday, September 4 |
| » Defeated Yankees (67-61), 7-1 | Polo Grounds V (5-5) | 73-53 | Won 2 |
| » Starters: Babe Ruth vs Allen Russell | First | -- |
| » Lost to Yankees (68-61), 4-3 | Polo Grounds V (5-6) | 73-54 | |
| » Starters: Dutch Leonard vs Bob Shawkey | First | -- |
| Tuesday, September 5 |
| » Lost to Athletics (29-98), 5-2 | Shibe Park (5-3) | 73-55 | Lost 2 |
| » Starters: Ernie Shore vs Jing Johnson | First | -- |
| » Defeated Athletics (29-99), 7-1 | Shibe Park (6-3) | 74-55 | |
| » Starters: Carl Mays vs Elmer Myers | First | -- |
| Wednesday, September 6 |
| » Defeated Athletics (29-100), 5-2 | Shibe Park (7-3) | 75-55 | Won 2 |
| » Starters: Dutch Leonard vs Tom Sheehan | First | -- |
| Thursday, September 7 |
| » Defeated Athletics (29-101), 2-0 | Shibe Park (8-3) | 76-55 | Won 3 |
| » Starters: Rube Foster vs Jack Nabors | First | -- |
| Friday, September 8 |
| » Tied Senators, 0-0 | Griffith Stadium (1-6) | 76-55 | |
| » Starters: Ernie Shore vs Jim Shaw | First | -- |
| Future Red Sox Jim Bagby Jr. is born in Cleveland, OH. |
| Saturday, September 9 |
| » Defeated Senators (66-65), 2-1 | Griffith Stadium (2-6) | 77-55 | Won 4 |
| » Starters: Babe Ruth vs Walter Johnson | First | -- |
| » Lost to Senators (67-65), 4-3 | Griffith Stadium (2-7) | 77-56 | |
| » Starters: Carl Mays vs Harry Harper | First | -- |
| Monday, September 11 |
| » Defeated Senators (67-66), 4-2 | Griffith Stadium (3-7) | 78-56 | |
| » Starters: Dutch Leonard vs Jim Shaw | First | -- |
| Tuesday, September 12 |
| » Lost to Senators (68-66), 4-3 | Griffith Stadium (3-8) | 78-57 | |
| » Starters: Babe Ruth vs Walter Johnson | First | -- |
| Thursday, September 14 |
| » Lost to Browns (73-67), 6-1 | Sportsman's Park III (4-6) | 78-58 | Lost 2 |
| » Starters: Ernie Shore vs Eddie Plank | First | -- |
| Friday, September 15 |
| » Defeated Browns (73-68), 8-3 | Sportsman's Park III (5-6) | 79-58 | |
| » Starters: Rube Foster vs Ernie Koob | First | -- |
| Saturday, September 16 |
| » Lost to White Sox (81-60), 6-4 | Comiskey Park I (5-4) | 79-59 | |
| » Starters: Dutch Leonard vs Lefty Williams | Third | 2 out |
| Sunday, September 17 |
| » Defeated White Sox (81-61), 6-2 | Comiskey Park I (6-4) | 80-59 | |
| » Starters: Babe Ruth vs Red Faber | Second | 2 out |
| Monday, September 18 |
| » Defeated White Sox (81-62), 4-3 | Comiskey Park I (7-4) | 81-59 | Won 2 |
| » Starters: Ernie Shore vs Lefty Williams | First | -- |
| Tuesday, September 19 |
| » Defeated Tigers (83-62), 3-1 | Tiger Stadium (5-4) | 82-59 | Won 3 |
| » Starters: Carl Mays vs Hooks Dauss | First | -- |
| Wednesday, September 20 |
| » Defeated Tigers (83-63), 4-3 | Tiger Stadium (6-4) | 83-59 | Won 4 |
| » Starters: Dutch Leonard vs Howard Ehmke | First | -- |
| Thursday, September 21 |
| » Defeated Tigers (83-64), 10-2 | Tiger Stadium (7-4) | 84-59 | Won 5 |
| » Starters: Babe Ruth vs Harry Coveleski | First | -- |
| Friday, September 22 |
| » Defeated Indians (75-72), 4-1 | League Park II (5-3) | 85-59 | Won 6 |
| » Starters: Ernie Shore vs Jim Bagby | First | -- |
| Saturday, September 23 |
| » Defeated Indians (75-73), 5-3 | League Park II (6-3) | 86-59 | Won 7 |
| » Starters: Carl Mays vs Otis Lambeth | First | -- |
| Sunday, September 24 |
| » Lost to Indians (76-73), 5-3 | League Park II (6-4) | 86-60 | |
| » Starters: Dutch Leonard vs Joe Boehling | First | -- |
| Monday, September 25 |
| » Defeated Indians (76-74), 2-0 | League Park II (7-4) | 87-60 | |
| » Starters: Babe Ruth vs Pop-boy Smith | First | -- |
| Wednesday, September 27 |
| » Defeated Yankees (76-72), 3-2 | Fenway Park (46-25) | 88-60 | Won 2 |
| » Starters: Urban Shocker vs Ernie Shore | First | -- |
| Thursday, September 28 |
| » Lost to Yankees (77-72), 4-2 | Fenway Park (46-26) | 88-61 | |
| » Starters: George Mogridge vs Carl Mays | First | -- |
| Future Red Sox Al Evans is born in Kenly, NC. |
| Friday, September 29 |
| » Defeated Yankees (77-73), 3-0 | Fenway Park (47-26) | 89-61 | |
| » Starters: Bob Shawkey vs Babe Ruth | First | -- |
| Saturday, September 30 |
| » Defeated Yankees (77-74), 1-0 | Fenway Park (48-26) | 90-61 | Won 2 |
| » Starters: Nick Cullop vs Dutch Leonard | First | -- |
| Monday, October 2 |
| » Defeated Athletics (34-117), 4-2 | Fenway Park (49-26) | 91-61 | Won 3 |
| » Starters: Jing Johnson vs Ernie Shore | First | -- |
| Tuesday, October 3 |
| » Lost to Athletics (35-117), 5-3 | Fenway Park (49-27) | 91-62 | |
| » Starters: Rube Parnham vs Carl Mays | First | -- |
| » Lost to Athletics (36-117), 7-5 | Fenway Park (49-28) | 91-63 | Lost 2 |
| » Starters: Elmer Myers vs Babe Ruth | First | -- |
| » Major-league debuts: Axel Lindstrom (Athletics) |
| Tuesday, October 10 |
| Future Red Sox Floyd Baker is born in Luray, VA. |
| Tuesday, October 31 |
| Future Red Sox Ken Keltner is born in Milwaukee, WI. |
| Sunday, November 5 |
| Future Red Sox Jim Tabor is born in New Hope, AL. |
| Sunday, November 26 |
| Future Red Sox Walt Ripley is born in Worcester, MA. |
| Wednesday, November 29 |
| Former Red Sox Bob Unglaub dies in Baltimore, MD at the age of 36. |
Game information provided by Retrosheet (www.retrosheet.org) |
