| Sunday, January 3 |
| Future Senator Sid Hudson is born in Coalfield, TN. |
| Wednesday, January 6 |
| Future Senator Tom Ferrick is born in New York, NY. Future Senator Tom Ferrick is born in New York, NY. |
| Sunday, January 17 |
| Future Senator Lum Harris is born in New Castle, AL. |
| Saturday, March 20 |
| Future Senator Stan Spence is born in South Portsmouth, KY. |
| Sunday, March 28 |
| Future Senator Joe Krakauskas is born in Montreal, PQ. |
| Thursday, April 1 |
| Future Senator Jeff Heath is born in Fort William, ON. |
| Friday, April 9 |
| Former Senator Rabbit Robinson dies in Waterbury, CT at the age of 34. |
| Wednesday, April 14 |
| » Defeated Yankees (0-1), 7-0 | Griffith Stadium (1-0) | 1-0 | |
| » Starters: Jack Warhop vs Walter Johnson | First | -- |
| Thursday, April 15 |
| » Lost to Yankees (1-1), 3-1 | Griffith Stadium (1-1) | 1-1 | |
| » Starters: Ray Fisher vs Harry Harper | Second | 1 out |
| Friday, April 16 |
| » Defeated Yankees (1-2), 3-2 | Griffith Stadium (2-1) | 2-1 | |
| » Starters: Boardwalk Brown vs Bert Gallia | First | -- |
| Saturday, April 17 |
| » Lost to Red Sox (2-1), 7-5 | Griffith Stadium (2-2) | 2-2 | |
| » Starters: Rube Foster vs Joe Boehling | Second | ½ out |
| Monday, April 19 |
| » Defeated Red Sox (2-2), 4-2 | Griffith Stadium (3-2) | 3-2 | |
| » Starters: Carl Mays vs Walter Johnson | Second | ½ out |
| Tuesday, April 20 |
| » Lost to Red Sox (3-2), 5-2 | Griffith Stadium (3-3) | 3-3 | |
| » Starters: Rube Foster vs Bert Gallia | Fourth | 1½ out |
| Wednesday, April 21 |
| » Defeated Red Sox (3-3), 11-3 | Griffith Stadium (4-3) | 4-3 | |
| » Starters: Ray Collins vs Joe Boehling | Third | 1½ out |
| » Major-league debuts: Mike McNally (Red Sox) |
| Thursday, April 22 |
| » Defeated Yankees (4-4), 5-1 | Polo Grounds V (1-0) | 5-3 | Won 2 |
| » Starters: Jim Shaw vs Marty McHale | Second | 1½ out |
| Saturday, April 24 |
| » Lost to Yankees (5-4), 4-0 | Polo Grounds V (1-1) | 5-4 | |
| » Starters: Walter Johnson vs Ray Caldwell | Second | 3 out |
| Monday, April 26 |
| » Lost to Yankees (6-4), 9-2 | Polo Grounds V (1-2) | 5-5 | Lost 2 |
| » Starters: Joe Boehling vs Ray Fisher | Fifth | 2½ out |
| Tuesday, April 27 |
| » Defeated Athletics (3-7), 2-1 | Griffith Stadium (5-3) | 6-5 | |
| » Starters: Bob Shawkey vs Jim Shaw | Fourth | 2½ out |
| Wednesday, April 28 |
| » Defeated Athletics (3-8), 1-0 | Griffith Stadium (6-3) | 7-5 | Won 2 |
| » Starters: Weldon Wyckoff vs Walter Johnson | Fourth | 2½ out |
| Thursday, April 29 |
| » Lost to Athletics (4-8), 3-1 | Griffith Stadium (6-4) | 7-6 | |
| » Starters: Herb Pennock vs Doc Ayers | Fourth | 3½ out |
| Friday, April 30 |
| » Defeated Athletics (4-9), 6-1 | Griffith Stadium (7-4) | 8-6 | |
| » Starters: Weldon Wyckoff vs Joe Boehling | Fourth | 2½ out |
| Tuesday, May 4 |
| » Lost to Red Sox (6-6), 2-0 | Fenway Park (0-1) | 8-7 | |
| » Starters: Walter Johnson vs Rube Foster | Fourth | 2½ out |
| Future Senator Ox Miller is born in Gause, TX. |
| Wednesday, May 5 |
| » Lost to Red Sox (7-6), 1-0 | Fenway Park (0-2) | 8-8 | Lost 2 |
| » Starters: Joe Boehling vs Ernie Shore | Fifth | 4½ out |
| Thursday, May 6 |
| » Defeated Athletics (5-12), 11-2 | Shibe Park (1-0) | 9-8 | |
| » Starters: Bert Gallia vs Herb Pennock | Fourth | 4 out |
| Friday, May 7 |
| » Lost to Athletics (6-12), 4-1 | Shibe Park (1-1) | 9-9 | |
| » Starters: Jack Bentley vs Bob Shawkey | Fifth | 5 out |
| Saturday, May 8 |
| » Lost to Athletics (7-12), 5-3 | Shibe Park (1-2) | 9-10 | Lost 2 |
| » Starters: Bert Gallia vs Weldon Wyckoff | Fifth | 5 out |
| Sunday, May 9 |
| » Lost to Tigers (17-7), 1-0 | Tiger Stadium (0-1) | 9-11 | Lost 3 |
| » Starters: Walter Johnson vs Jean Dubuc | Sixth | 6 out |
| Tuesday, May 11 |
| » Defeated White Sox (14-10), 2-0 | Comiskey Park I (1-0) | 10-11 | |
| » Starters: Jim Shaw vs Jim Scott | Sixth | 6 out |
| Wednesday, May 12 |
| » Lost to White Sox (15-10), 4-1 | Comiskey Park I (1-1) | 10-12 | |
| » Starters: Bert Gallia vs Red Faber | Sixth | 6 out |
| Thursday, May 13 |
| » Lost to White Sox (16-10), 4-3 | Comiskey Park I (1-2) | 10-13 | Lost 2 |
| » Starters: Walter Johnson vs Eddie Cicotte | Sixth | 6 out |
| Saturday, May 15 |
| » Defeated White Sox (16-11), 3-1 | Comiskey Park I (2-2) | 11-13 | |
| » Starters: Joe Boehling vs Mellie Wolfgang | Fifth | 4½ out |
| Sunday, May 16 |
| » Lost to Browns (10-18), 2-1 | Sportsman's Park III (0-1) | 11-14 | |
| » Starters: Jim Shaw vs Carl Weilman | Fifth | 5½ out |
| Monday, May 17 |
| » Defeated Browns (10-19), 3-2 | Sportsman's Park III (1-1) | 12-14 | |
| » Starters: Walter Johnson vs Grover Lowdermilk | Fifth | 5 out |
| Wednesday, May 19 |
| Future Senator Jake Early is born in Kings Mountain, NC. |
| Saturday, May 22 |
| » Lost to Indians (13-16), 7-6 | League Park II (0-1) | 12-15 | |
| » Starters: Joe Boehling vs Bill Steen | Sixth | 6 out |
| Sunday, May 23 |
| » Defeated Indians (13-17), 4-1 | League Park II (1-1) | 13-15 | |
| » Starters: Walter Johnson vs Guy Morton | Fifth | 6 out |
| Monday, May 24 |
| » Lost to Tigers (22-12), 4-0 | Tiger Stadium (0-2) | 13-16 | |
| » Starters: Joe Boehling vs Harry Coveleski | Fifth | 7 out |
| Tuesday, May 25 |
| » Defeated Tigers (22-13), 8-4 | Tiger Stadium (1-2) | 14-16 | |
| » Starters: Bert Gallia vs Pug Cavet | Fifth | 6½ out |
| Wednesday, May 26 |
| » Lost to Tigers (23-13), 10-5 | Tiger Stadium (1-3) | 14-17 | |
| » Starters: Jim Shaw vs Jean Dubuc | Fifth | 7½ out |
| Thursday, May 27 |
| » Defeated Tigers (23-14), 8-2 | Tiger Stadium (2-3) | 15-17 | |
| » Starters: Walter Johnson vs Bernie Boland | Fifth | 7½ out |
| Saturday, May 29 |
| » Major-league debuts: Muddy Ruel (Browns) |
| Monday, May 31 |
| » Lost to Yankees (18-15), 11-4 | Griffith Stadium (7-5) | 15-18 | |
| » Starters: Ray Caldwell vs Jim Shaw | Sixth | 8 out |
| » Lost to Yankees (19-15), 4-1 | Griffith Stadium (7-6) | 15-19 | Lost 2 |
| » Starters: Ray Fisher vs Joe Boehling | Sixth | 8 out |
| Tuesday, June 1 |
| » Defeated Athletics (13-27), 5-3 | Shibe Park (2-2) | 16-19 | |
| » Starters: Walter Johnson vs Weldon Wyckoff | Sixth | 8 out |
| Friday, June 4 |
| » Defeated Indians (17-22), 6-1 | Griffith Stadium (8-6) | 17-19 | Won 2 |
| » Starters: Bill Steen vs Jim Shaw | Fifth | 7½ out |
| Saturday, June 5 |
| » Lost to Indians (18-22), 5-4 | Griffith Stadium (8-7) | 17-20 | |
| » Starters: Roy Walker vs Walter Johnson | Fifth | 7½ out |
| Monday, June 7 |
| » Defeated Indians (18-23), 6-3 | Griffith Stadium (9-7) | 18-20 | |
| » Starters: Guy Morton vs Joe Boehling | Fifth | 7½ out |
| Tuesday, June 8 |
| » Defeated Indians (18-24), 3-2 | Griffith Stadium (10-7) | 19-20 | Won 2 |
| » Starters: Fritz Coumbe vs Doc Ayers | Fifth | 6½ out |
| Wednesday, June 9 |
| » Defeated Browns (18-27), 4-1 | Griffith Stadium (11-7) | 20-20 | Won 3 |
| » Starters: Carl Weilman vs Jim Shaw | Fourth | 6½ out |
| Thursday, June 10 |
| » Defeated Browns (18-28), 8-2 | Griffith Stadium (12-7) | 21-20 | Won 4 |
| » Starters: Harry Hoch vs Walter Johnson | Fourth | 6½ out |
| Friday, June 11 |
| » Lost to Browns (19-28), 5-1 | Griffith Stadium (12-8) | 21-21 | |
| » Starters: Bill James vs Bert Gallia | Fourth | 6½ out |
| Saturday, June 12 |
| » Defeated White Sox (31-19), 2-1 | Griffith Stadium (13-8) | 22-21 | |
| » Starters: Joe Benz vs Joe Boehling | Fourth | 5½ out |
| Monday, June 14 |
| » Lost to White Sox (32-19), 8-2 | Griffith Stadium (13-9) | 22-22 | |
| » Starters: Eddie Cicotte vs Jim Shaw | Fifth | 6½ out |
| Wednesday, June 16 |
| » Defeated White Sox (32-20), 5-2 | Griffith Stadium (14-9) | 23-22 | |
| » Starters: Reb Russell vs Walter Johnson | Fifth | 5½ out |
| Thursday, June 17 |
| » Lost to Tigers (33-22), 4-2 | Griffith Stadium (14-10) | 23-23 | |
| » Starters: Jean Dubuc vs Doc Ayers | Fifth | 6½ out |
| Friday, June 18 |
| » Lost to Tigers (34-22), 5-3 | Griffith Stadium (14-11) | 23-24 | Lost 2 |
| » Starters: Bill Steen vs Joe Boehling | Fifth | 7½ out |
| Saturday, June 19 |
| » Defeated Tigers (34-23), 7-0 | Griffith Stadium (15-11) | 24-24 | |
| » Starters: Harry Coveleski vs Walter Johnson | Fifth | 7½ out |
| Monday, June 21 |
| » Lost to Red Sox (29-18), 8-3 | Griffith Stadium (15-12) | 24-25 | |
| » Starters: Babe Ruth vs Jim Shaw | Fifth | 8½ out |
| » Defeated Red Sox (29-19), 6-5 | Griffith Stadium (16-12) | 25-25 | |
| » Starters: Ernie Shore vs Joe Boehling | Fifth | 8½ out |
| Tuesday, June 22 |
| » Defeated Red Sox (29-20), 7-4 | Griffith Stadium (17-12) | 26-25 | Won 2 |
| » Starters: Rube Foster vs Doc Ayers | Fourth | 8½ out |
| Wednesday, June 23 |
| » Defeated Red Sox (29-21), 5-0 | Griffith Stadium (18-12) | 27-25 | Won 3 |
| » Starters: Carl Mays vs Walter Johnson | Fifth | 9 out |
| Thursday, June 24 |
| » Lost to Red Sox (30-21), 12-4 | Griffith Stadium (18-13) | 27-26 | |
| » Starters: Ray Collins vs Joe Boehling | Fifth | 10 out |
| Friday, June 25 |
| » Defeated Athletics (21-38), 4-1 | Griffith Stadium (19-13) | 28-26 | |
| » Starters: Weldon Wyckoff vs Bert Gallia | Fifth | 9½ out |
| Saturday, June 26 |
| » Lost to Athletics (22-38), 3-2 | Griffith Stadium (19-14) | 28-27 | |
| » Starters: Bullet Joe Bush vs Jim Shaw | Fifth | 9½ out |
| Monday, June 28 |
| » Defeated Athletics (22-39), 2-0 | Griffith Stadium (20-14) | 29-27 | |
| » Starters: Cap Crowell vs Walter Johnson | Fifth | 10 out |
| Tuesday, June 29 |
| » Defeated Athletics (22-40), 8-0 | Griffith Stadium (21-14) | 30-27 | Won 2 |
| » Starters: Weldon Wyckoff vs Joe Boehling | Fourth | 10 out |
| Wednesday, June 30 |
| » Lost to Yankees (33-30), 4-1 | Polo Grounds V (1-3) | 30-28 | |
| » Starters: Jim Shaw vs Jack Warhop | Fifth | 11 out |
| Future Senator Roberto Ortiz is born in Camaguey, Cuba. |
| Thursday, July 1 |
| » Defeated Yankees (33-31), 5-3 | Polo Grounds V (2-3) | 31-28 | |
| » Starters: Bert Gallia vs Ray Fisher | Fourth | 11 out |
| Friday, July 2 |
| » Lost to Yankees (34-31), 1-0 | Polo Grounds V (2-4) | 31-29 | |
| » Starters: Jim Shaw vs Cy Pieh | Fifth | 11 out |
| Saturday, July 3 |
| » Defeated Yankees (34-32), 8-7 | Polo Grounds V (3-4) | 32-29 | |
| » Starters: Joe Boehling vs Jack Warhop | Fifth | 10½ out |
| » Lost to Yankees (35-32), 4-1 | Polo Grounds V (3-5) | 32-30 | |
| » Starters: Walter Johnson vs Ray Caldwell | Fifth | 10½ out |
| Monday, July 5 |
| » Lost to Red Sox (38-24), 4-0 | Fenway Park (0-3) | 32-31 | Lost 2 |
| » Starters: Doc Ayers vs Rube Foster | Fifth | 10 out |
| » Lost to Red Sox (39-24), 6-0 | Fenway Park (0-4) | 32-32 | Lost 3 |
| » Starters: Jim Shaw vs Babe Ruth | Fifth | 10 out |
| Tuesday, July 6 |
| » Lost to Red Sox (40-24), 5-1 | Fenway Park (0-5) | 32-33 | Lost 4 |
| » Starters: Joe Boehling vs Ernie Shore | Fifth | 11½ out |
| » Lost to Red Sox (41-24), 4-1 | Fenway Park (0-6) | 32-34 | Lost 5 |
| » Starters: Walter Johnson vs Vean Gregg | Fifth | 11½ out |
| Wednesday, July 7 |
| » Lost to Red Sox (42-24), 9-4 | Fenway Park (0-7) | 32-35 | Lost 6 |
| » Starters: Bert Gallia vs Joe Wood | Fifth | 12½ out |
| » Lost to Red Sox (43-24), 1-0 | Fenway Park (0-8) | 32-36 | Lost 7 |
| » Starters: Joe Engel vs Dutch Leonard | Fifth | 12½ out |
| Friday, July 9 |
| » Lost to White Sox (48-26), 5-1 | Comiskey Park I (2-3) | 32-37 | Lost 8 |
| » Starters: Jim Shaw vs Jim Scott | Fifth | 13½ out |
| Saturday, July 10 |
| » Tied White Sox, 1-1 | Comiskey Park I (2-3) | 32-37 | |
| » Starters: Walter Johnson vs Joe Benz | Fifth | 13½ out |
| Sunday, July 11 |
| » Defeated White Sox (48-27), 8-3 | Comiskey Park I (3-3) | 33-37 | |
| » Starters: Bert Gallia vs Red Faber | Fifth | 13½ out |
| » Lost to White Sox (49-27), 12-5 | Comiskey Park I (3-4) | 33-38 | |
| » Starters: Joe Engel vs Eddie Cicotte | Fifth | 13½ out |
| Monday, July 12 |
| » Defeated White Sox (49-28), 5-3 | Comiskey Park I (4-4) | 34-38 | |
| » Starters: Jim Shaw vs Ed Klepfer | Fifth | 12½ out |
| Tuesday, July 13 |
| » Defeated Browns (28-45), 3-2 | Sportsman's Park III (2-1) | 35-38 | Won 2 |
| » Starters: Joe Boehling vs Bill James | Fifth | 13 out |
| » Lost to Browns (29-45), 3-0 | Sportsman's Park III (2-2) | 35-39 | |
| » Starters: Walter Johnson vs Carl Weilman | Fifth | 13 out |
| Wednesday, July 14 |
| » Defeated Browns (29-46), 2-1 | Sportsman's Park III (3-2) | 36-39 | |
| » Starters: Bert Gallia vs Grover Lowdermilk | Fifth | 13 out |
| Thursday, July 15 |
| » Lost to Browns (30-46), 5-2 | Sportsman's Park III (3-3) | 36-40 | |
| » Starters: Joe Engel vs George Sisler | Fifth | 13½ out |
| » Lost to Browns (31-46), 4-3 | Sportsman's Park III (3-4) | 36-41 | Lost 2 |
| » Starters: Jim Shaw vs Earl Hamilton | Fifth | 13½ out |
| Friday, July 16 |
| » Defeated Browns (31-47), 6-2 | Sportsman's Park III (4-4) | 37-41 | |
| » Starters: Walter Johnson vs Walt Leverenz | Fifth | 13½ out |
| Saturday, July 17 |
| » Defeated Indians (28-50), 3-2 | League Park II (2-1) | 38-41 | Won 2 |
| » Starters: Joe Boehling vs Roy Walker | Fifth | 12½ out |
| » Defeated Indians (28-51), 10-4 | League Park II (3-1) | 39-41 | Won 3 |
| » Starters: Doc Ayers vs Oscar Harstad | Fifth | 12½ out |
| Sunday, July 18 |
| » Defeated Indians (28-52), 4-2 | League Park II (4-1) | 40-41 | Won 4 |
| » Starters: Bert Gallia vs Guy Morton | Fifth | 10½ out |
| » Defeated Indians (28-53), 4-3 | League Park II (5-1) | 41-41 | Won 5 |
| » Starters: Doc Ayers vs Willie Mitchell | Fifth | 10½ out |
| Monday, July 19 |
| » Defeated Indians (28-54), 11-4 | League Park II (6-1) | 42-41 | Won 6 |
| » Starters: Walter Johnson vs Rip Hagerman | Fifth | 10½ out |
| Tuesday, July 20 |
| » Lost to Indians (29-54), 5-4 | League Park II (6-2) | 42-42 | |
| » Starters: Jim Shaw vs Roy Walker | Fifth | 11½ out |
| Friday, July 23 |
| » Lost to Tigers (53-32), 2-1 | Tiger Stadium (2-4) | 42-43 | Lost 2 |
| » Starters: Bert Gallia vs Harry Coveleski | Fourth | 13½ out |
| Saturday, July 24 |
| » Lost to Tigers (54-32), 2-0 | Tiger Stadium (2-5) | 42-44 | Lost 3 |
| » Starters: Walter Johnson vs Jean Dubuc | Fourth | 13½ out |
| » Defeated Tigers (54-33), 8-5 | Tiger Stadium (3-5) | 43-44 | |
| » Starters: Joe Boehling vs Hooks Dauss | Fourth | 13½ out |
| Sunday, July 25 |
| » Defeated Tigers (54-34), 3-2 | Tiger Stadium (4-5) | 44-44 | Won 2 |
| » Starters: Doc Ayers vs Hooks Dauss | Fourth | 12½ out |
| Tuesday, July 27 |
| » Defeated Indians (34-55), 1-0 | Griffith Stadium (22-14) | 45-44 | Won 3 |
| » Starters: Rip Hagerman vs Bert Gallia | Fourth | 12½ out |
| Future Senator Dick Kimble is born in Buchtel, OH. |
| Wednesday, July 28 |
| » Lost to Indians (35-55), 10-1 | Griffith Stadium (22-15) | 45-45 | |
| » Starters: Sad Sam Jones vs Joe Boehling | Fourth | 12½ out |
| Thursday, July 29 |
| » Defeated Indians (35-56), 2-1 | Griffith Stadium (23-15) | 46-45 | |
| » Starters: Roy Walker vs Walter Johnson | Fourth | 12 out |
| Friday, July 30 |
| » Defeated Browns (37-55), 3-0 | Griffith Stadium (24-15) | 47-45 | Won 2 |
| » Starters: Carl Weilman vs Doc Ayers | Fourth | 11 out |
| Saturday, July 31 |
| » Lost to Browns (38-55), 5-3 | Griffith Stadium (24-16) | 47-46 | |
| » Starters: Earl Hamilton vs Bert Gallia | Fourth | 12 out |
| Monday, August 2 |
| » Defeated Browns (38-56), 5-1 | Griffith Stadium (25-16) | 48-46 | |
| » Starters: George Sisler vs Walter Johnson | Third | 11 out |
| » Major-league debuts: Merlin Kopp (Senators) |
| Tuesday, August 3 |
| » Defeated Browns (38-57), 1-0 | Griffith Stadium (26-16) | 49-46 | Won 2 |
| » Starters: Ernie Koob vs Doc Ayers | Fourth | 11 out |
| Wednesday, August 4 |
| » Defeated White Sox (58-37), 1-0 | Griffith Stadium (27-16) | 50-46 | Won 3 |
| » Starters: Jim Scott vs Joe Boehling | Fourth | 10 out |
| » Defeated White Sox (58-38), 3-1 | Griffith Stadium (28-16) | 51-46 | Won 4 |
| » Starters: Eddie Cicotte vs Bert Gallia | Fourth | 10 out |
| Friday, August 6 |
| » Defeated White Sox (58-39), 8-6 | Griffith Stadium (29-16) | 52-46 | Won 5 |
| » Starters: Joe Benz vs Walter Johnson | Fourth | 9 out |
| » Defeated White Sox (58-40), 6-3 | Griffith Stadium (30-16) | 53-46 | Won 6 |
| » Starters: Reb Russell vs Doc Ayers | Fourth | 9 out |
| Saturday, August 7 |
| » Lost to White Sox (59-40), 6-2 | Griffith Stadium (30-17) | 53-47 | |
| » Starters: Jim Scott vs Bert Gallia | Fourth | 10½ out |
| » Major-league debuts: Sam Rice (Senators) |
| Monday, August 9 |
| » Lost to Tigers (63-38), 5-3 | Griffith Stadium (30-18) | 53-48 | Lost 2 |
| » Starters: Hooks Dauss vs Joe Boehling | Fourth | 11½ out |
| Tuesday, August 10 |
| » Lost to Tigers (64-38), 8-2 | Griffith Stadium (30-19) | 53-49 | Lost 3 |
| » Starters: Bill Steen vs Walter Johnson | Fourth | 12 out |
| Wednesday, August 11 |
| » Defeated Tigers (64-39), 3-0 | Griffith Stadium (31-19) | 54-49 | |
| » Starters: Harry Coveleski vs Bert Gallia | Fourth | 12½ out |
| Friday, August 13 |
| » Lost to Red Sox (67-35), 3-2 | Fenway Park (0-9) | 54-50 | |
| » Starters: Joe Boehling vs Ernie Shore | Fourth | 14 out |
| Saturday, August 14 |
| » Lost to Red Sox (68-35), 4-3 | Fenway Park (0-10) | 54-51 | Lost 2 |
| » Starters: Walter Johnson vs Babe Ruth | Fourth | 15 out |
| Monday, August 16 |
| » Lost to Red Sox (69-35), 1-0 | Fenway Park (0-11) | 54-52 | Lost 3 |
| » Starters: Bert Gallia vs Joe Wood | Fourth | 16 out |
| Wednesday, August 18 |
| » Lost to Indians (42-66), 3-0 | League Park II (6-3) | 54-53 | Lost 4 |
| » Starters: Walter Johnson vs Allan Collamore | Fourth | 16 out |
| Thursday, August 19 |
| » Defeated Indians (42-67), 11-6 | League Park II (7-3) | 55-53 | |
| » Starters: Joe Boehling vs Sad Sam Jones | Fourth | 15 out |
| » Major-league debuts: Turner Barber (Senators) |
| Friday, August 20 |
| » Defeated Indians (42-68), 8-0 | League Park II (8-3) | 56-53 | Won 2 |
| » Starters: Harry Harper vs Lynn Brenton | Fourth | 15 out |
| Sunday, August 22 |
| » Defeated Tigers (73-40), 8-1 | Tiger Stadium (5-5) | 57-53 | Won 3 |
| » Starters: Walter Johnson vs Jean Dubuc | Fourth | 16½ out |
| » Lost to Tigers (74-40), 1-0 | Tiger Stadium (5-6) | 57-54 | |
| » Starters: Bert Gallia vs Hooks Dauss | Fourth | 16½ out |
| Monday, August 23 |
| Future Senator Gil Torres is born in Regla, Cuba. |
| Tuesday, August 24 |
| » Lost to White Sox (71-44), 6-5 | Comiskey Park I (4-5) | 57-55 | Lost 2 |
| » Starters: Joe Boehling vs Jim Scott | Fourth | 18 out |
| Wednesday, August 25 |
| » Defeated White Sox (71-45), 7-4 | Comiskey Park I (5-5) | 58-55 | |
| » Starters: Bert Gallia vs Eddie Cicotte | Fourth | 18 out |
| Thursday, August 26 |
| » Defeated White Sox (71-46), 2-1 | Comiskey Park I (6-5) | 59-55 | Won 2 |
| » Starters: Joe Boehling vs Reb Russell | Fourth | 17 out |
| Friday, August 27 |
| » Defeated Browns (45-73), 3-1 | Sportsman's Park III (5-4) | 60-55 | Won 3 |
| » Starters: Harry Harper vs Grover Lowdermilk | Fourth | 16 out |
| Saturday, August 28 |
| » Lost to Browns (46-73), 2-1 | Sportsman's Park III (5-5) | 60-56 | |
| » Starters: Doc Ayers vs Earl Hamilton | Fourth | 17½ out |
| Sunday, August 29 |
| » Lost to Browns (47-73), 2-1 | Sportsman's Park III (5-6) | 60-57 | Lost 2 |
| » Starters: Walter Johnson vs George Sisler | Fourth | 18½ out |
| » Major-league debuts: Horace Milan (Senators) |
| Tuesday, August 31 |
| » Defeated Yankees (55-61), 4-1 | Griffith Stadium (32-19) | 61-57 | |
| » Starters: Boardwalk Brown vs Bert Gallia | Fourth | 17½ out |
| » Defeated Yankees (55-62), 3-2 | Griffith Stadium (33-19) | 62-57 | Won 2 |
| » Starters: Ray Fisher vs Joe Boehling | Fourth | 17½ out |
| Wednesday, September 1 |
| » Defeated Yankees (55-63), 2-1 | Griffith Stadium (34-19) | 63-57 | Won 3 |
| » Starters: Ray Caldwell vs Doc Ayers | Fourth | 17½ out |
| Thursday, September 2 |
| » Lost to Yankees (56-63), 1-0 | Griffith Stadium (34-20) | 63-58 | |
| » Starters: Bob Shawkey vs Harry Harper | Fourth | 18½ out |
| Friday, September 3 |
| » Defeated Yankees (56-64), 2-0 | Griffith Stadium (35-20) | 64-58 | |
| » Starters: Cy Pieh vs Walter Johnson | Fourth | 18½ out |
| Saturday, September 4 |
| » Defeated Yankees (56-65), 4-3 | Griffith Stadium (36-20) | 65-58 | Won 2 |
| » Starters: Boardwalk Brown vs Joe Boehling | Fourth | 18½ out |
| Monday, September 6 |
| » Defeated Athletics (36-86), 5-3 | Shibe Park (3-2) | 66-58 | Won 3 |
| » Starters: Doc Ayers vs Tom Sheehan | Fourth | 16½ out |
| » Defeated Athletics (36-87), 5-0 | Shibe Park (4-2) | 67-58 | Won 4 |
| » Starters: Harry Harper vs Jack Nabors | Fourth | 16½ out |
| Tuesday, September 7 |
| » Lost to Athletics (37-87), 6-5 | Shibe Park (4-3) | 67-59 | |
| » Starters: Bert Gallia vs Walter Ancker | Fourth | 16 out |
| » Defeated Athletics (37-88), 7-4 | Shibe Park (5-3) | 68-59 | |
| » Starters: Sam Rice vs Dana Fillingim | Fourth | 16 out |
| Wednesday, September 8 |
| » Defeated Yankees (59-66), 1-0 | Polo Grounds V (4-5) | 69-59 | Won 2 |
| » Starters: Walter Johnson vs Bob Shawkey | Fourth | 15½ out |
| Thursday, September 9 |
| » Defeated Yankees (59-67), 5-3 | Polo Grounds V (5-5) | 70-59 | Won 3 |
| » Starters: Harry Harper vs Boardwalk Brown | Fourth | 15 out |
| » Defeated Yankees (59-68), 4-1 | Polo Grounds V (6-5) | 71-59 | Won 4 |
| » Starters: Bert Gallia vs Cy Pieh | Fourth | 15 out |
| Saturday, September 11 |
| » Defeated Indians (50-83), 5-4 | Griffith Stadium (37-20) | 72-59 | Won 5 |
| » Starters: Allan Collamore vs Sam Rice | Fourth | 15½ out |
| Monday, September 13 |
| » Defeated Indians (50-84), 3-2 | Griffith Stadium (38-20) | 73-59 | Won 6 |
| » Starters: Clarence Garrett vs Joe Boehling | Fourth | 16 out |
| Tuesday, September 14 |
| » Defeated Indians (50-85), 3-0 | Griffith Stadium (39-20) | 74-59 | Won 7 |
| » Starters: Paul Carter vs George Dumont | Fourth | 16 out |
| » Major-league debuts: George Dumont and Sam Mayer (Senators) |
| Wednesday, September 15 |
| » Lost to Indians (51-85), 5-0 | Griffith Stadium (39-21) | 74-60 | |
| » Starters: Lynn Brenton vs Harry Harper | Fourth | 16 out |
| Thursday, September 16 |
| » Defeated Browns (57-79), 8-2 | Griffith Stadium (40-21) | 75-60 | |
| » Starters: Pete Sims vs Walter Johnson | Fourth | 15 out |
| » Major-league debuts: Pete Sims (Browns) |
| Friday, September 17 |
| » Lost to Browns (58-79), 9-0 | Griffith Stadium (40-22) | 75-61 | |
| » Starters: Tim McCabe vs Joe Boehling | Fourth | 16 out |
| Saturday, September 18 |
| » Defeated Browns (58-80), 1-0 | Griffith Stadium (41-22) | 76-61 | |
| » Starters: Tom Phillips vs Bert Gallia | Fourth | 16 out |
| Monday, September 20 |
| » Defeated Browns (58-81), 6-0 | Griffith Stadium (42-22) | 77-61 | Won 2 |
| » Starters: Allen Sothoron vs George Dumont | Fourth | 16 out |
| » Major-league debuts: Charlie Jamieson and Joe Judge (Senators) |
| Tuesday, September 21 |
| » Defeated White Sox (82-60), 7-1 | Griffith Stadium (43-22) | 78-61 | Won 3 |
| » Starters: Red Faber vs Walter Johnson | Fourth | 15½ out |
| Wednesday, September 22 |
| » Defeated White Sox (82-61), 2-0 | Griffith Stadium (44-22) | 79-61 | Won 4 |
| » Starters: Joe Benz vs Bert Gallia | Fourth | 16 out |
| Thursday, September 23 |
| » Lost to White Sox (83-61), 2-1 | Griffith Stadium (44-23) | 79-62 | |
| » Starters: Jim Scott vs Harry Harper | Fourth | 17½ out |
| Friday, September 24 |
| » Defeated Tigers (94-52), 11-4 | Griffith Stadium (45-23) | 80-62 | |
| » Starters: Harry Coveleski vs Walter Johnson | Fourth | 16½ out |
| Saturday, September 25 |
| » Lost to Tigers (95-52), 5-1 | Griffith Stadium (45-24) | 80-63 | |
| » Starters: Hooks Dauss vs George Dumont | Fourth | 18 out |
| » Lost to Tigers (96-52), 9-3 | Griffith Stadium (45-25) | 80-64 | Lost 2 |
| » Starters: Bill James vs Bert Gallia | Fourth | 18 out |
| Monday, September 27 |
| » Lost to Tigers (97-52), 7-5 | Griffith Stadium (45-26) | 80-65 | Lost 3 |
| » Starters: Harry Coveleski vs Joe Boehling | Fourth | 19 out |
| Tuesday, September 28 |
| » Defeated Tigers (97-53), 3-0 | Griffith Stadium (46-26) | 81-65 | |
| » Starters: Red Oldham vs Walter Johnson | Fourth | 18½ out |
| Wednesday, September 29 |
| » Defeated Athletics (40-107), 10-2 | Griffith Stadium (47-26) | 82-65 | Won 2 |
| » Starters: Bud Davis vs Doc Ayers | Fourth | 17½ out |
| » Defeated Athletics (40-108), 20-5 | Griffith Stadium (48-26) | 83-65 | Won 3 |
| » Starters: Tom Sheehan vs Bert Gallia | Fourth | 17½ out |
| Thursday, September 30 |
| » Lost to Athletics (41-108), 4-3 | Griffith Stadium (48-27) | 83-66 | |
| » Starters: Joe Sherman vs Harry Harper | Fourth | 18 out |
| Saturday, October 2 |
| » Defeated Red Sox (99-47), 3-1 | Griffith Stadium (49-27) | 84-66 | |
| » Starters: Joe Wood vs Walter Johnson | Fourth | 17 out |
| » Tied Red Sox, 3-3 | Griffith Stadium (49-27) | 84-66 | |
| » Starters: Ernie Shore vs George Dumont | Fourth | 17 out |
| Sunday, October 3 |
| Future Senator Charlie Letchas is born in Thomasville, GA. |
| Monday, October 4 |
| » Defeated Athletics (41-109), 7-3 | Griffith Stadium (50-27) | 85-66 | Won 2 |
| » Starters: Jack Nabors vs Harry Harper | Fourth | 15½ out |
| Wednesday, October 6 |
| » Lost to Athletics (42-109), 6-4 | Griffith Stadium (50-28) | 85-67 | |
| » Starters: Jack Richardson vs Doc Ayers | Fourth | 17½ out |
| » Lost to Athletics (43-109), 4-0 | Griffith Stadium (50-29) | 85-68 | Lost 2 |
| » Starters: Elmer Myers vs Jack Bentley | Fourth | 17½ out |
| Thursday, November 11 |
| Future Senator George Case is born in Trenton, NJ. Future Senator Bill Lefebvre is born in Natick, RI. |
Game information provided by Retrosheet (www.retrosheet.org) |