| Wednesday, April 8 |
| Future Red Sox Andy Karl is born in Mount Vernon, NY. |
| Tuesday, April 14 |
| » Lost to Senators (1-0), 3-0 | Fenway Park (0-1) | 0-1 | |
| » Starters: Walter Johnson vs Ray Collins | Second | 1 out |
| » Major-league debuts: Everett Scott (Red Sox) |
| Wednesday, April 15 |
| » Defeated Senators (1-1), 2-1 | Fenway Park (1-1) | 1-1 | |
| » Starters: Doc Ayers vs Rube Foster | Third | 1 out |
| Friday, April 17 |
| » Lost to Senators (2-1), 1-0 | Fenway Park (1-2) | 1-2 | |
| » Starters: Joe Boehling vs Dutch Leonard | Fourth | 2½ out |
| Saturday, April 18 |
| » Defeated Athletics (0-3), 1-0 | Fenway Park (2-2) | 2-2 | |
| » Starters: Bob Shawkey vs Hugh Bedient | Fourth | 2½ out |
| Monday, April 20 |
| » Lost to Athletics (1-3), 8-2 | Fenway Park (2-3) | 2-3 | |
| » Starters: Byron Houck vs Ray Collins | Sixth | 3 out |
| » Lost to Athletics (2-3), 6-0 | Fenway Park (2-4) | 2-4 | Lost 2 |
| » Starters: Herb Pennock vs Rube Foster | Sixth | 3 out |
| » Major-league debuts: Rankin Johnson (Red Sox) |
| Tuesday, April 21 |
| » Tied Athletics, 1-1 | Fenway Park (2-4) | 2-4 | |
| » Starters: Bob Shawkey vs Dutch Leonard | Seventh | 3½ out |
| Wednesday, April 22 |
| » Tied Athletics, 9-9 | Fenway Park (2-4) | 2-4 | |
| » Starters: Byron Houck vs Hugh Bedient | Seventh | 4 out |
| » Major-league debuts: Fritz Coumbe (Red Sox) |
| Thursday, April 23 |
| » Defeated Senators (4-3), 5-0 | Griffith Stadium (1-0) | 3-4 | |
| » Starters: Adam Johnson vs Walter Johnson | Fifth | 3 out |
| Friday, April 24 |
| » Defeated Senators (4-4), 5-3 | Griffith Stadium (2-0) | 4-4 | Won 2 |
| » Starters: Ray Collins vs Joe Engel | Fourth | 2½ out |
| Monday, April 27 |
| » Lost to Senators (5-4), 6-1 | Griffith Stadium (2-1) | 4-5 | |
| » Starters: Rube Foster vs Joe Boehling | Fifth | 2 out |
| Wednesday, April 29 |
| » Lost to Yankees (5-4), 1-0 | Polo Grounds V (0-1) | 4-6 | Lost 2 |
| » Starters: Dutch Leonard vs Ray Fisher | Seventh | 3½ out |
| Friday, May 1 |
| » Lost to Yankees (6-4), 6-0 | Polo Grounds V (0-2) | 4-7 | Lost 3 |
| » Starters: Hugh Bedient vs Ray Caldwell | Seventh | 5 out |
| Saturday, May 2 |
| » Lost to Athletics (7-5), 5-2 | Shibe Park (0-1) | 4-8 | Lost 4 |
| » Starters: Adam Johnson vs Eddie Plank | Seventh | 5 out |
| Monday, May 4 |
| » Defeated Athletics (7-6), 9-1 | Shibe Park (1-1) | 5-8 | |
| » Starters: Dutch Leonard vs Weldon Wyckoff | Seventh | 5½ out |
| Wednesday, May 6 |
| » Lost to Athletics (8-6), 7-3 | Shibe Park (1-2) | 5-9 | |
| » Starters: Ray Collins vs Bullet Joe Bush | Sixth | 6 out |
| Thursday, May 7 |
| » Defeated Yankees (8-7), 2-0 | Fenway Park (3-4) | 6-9 | |
| » Starters: Ray Fisher vs Rube Foster | Sixth | 5½ out |
| Friday, May 8 |
| » Defeated Yankees (8-8), 3-0 | Fenway Park (4-4) | 7-9 | Won 2 |
| » Starters: Ray Keating vs Dutch Leonard | Sixth | 5½ out |
| Saturday, May 9 |
| » Lost to Yankees (9-8), 3-2 | Fenway Park (4-5) | 7-10 | |
| » Starters: Marty McHale vs Ray Collins | Sixth | 6½ out |
| Monday, May 11 |
| » Lost to Yankees (10-8), 6-2 | Fenway Park (4-6) | 7-11 | Lost 2 |
| » Starters: Ray Caldwell vs Fritz Coumbe | Seventh | 6½ out |
| Tuesday, May 12 |
| » Defeated Browns (11-11), 7-0 | Fenway Park (5-6) | 8-11 | |
| » Starters: Wiley Taylor vs Rube Foster | Sixth | 6½ out |
| Thursday, May 14 |
| » Defeated Browns (11-12), 1-0 | Fenway Park (6-6) | 9-11 | Won 2 |
| » Starters: Earl Hamilton vs Dutch Leonard | Sixth | 6½ out |
| Friday, May 15 |
| » Lost to Browns (12-12), 9-3 | Fenway Park (6-7) | 9-12 | |
| » Starters: Carl Weilman vs Hugh Bedient | Sixth | 7½ out |
| Saturday, May 16 |
| » Defeated Tigers (19-8), 3-0 | Fenway Park (7-7) | 10-12 | |
| » Starters: Harry Coveleski vs Ray Collins | Sixth | 6½ out |
| » Major-league debuts: Harry Heilmann (Tigers) |
| Monday, May 18 |
| » Defeated Tigers (19-9), 2-0 | Fenway Park (8-7) | 11-12 | Won 2 |
| » Starters: Alex Main vs Rube Foster | Fifth | 5½ out |
| Tuesday, May 19 |
| » Defeated Tigers (19-10), 6-4 | Fenway Park (9-7) | 12-12 | Won 3 |
| » Starters: Jean Dubuc vs Hugh Bedient | Fifth | 4½ out |
| Wednesday, May 20 |
| » Lost to Tigers (20-10), 3-0 | Fenway Park (9-8) | 12-13 | |
| » Starters: Hooks Dauss vs Ray Collins | Fifth | 5½ out |
| Thursday, May 21 |
| » Lost to White Sox (14-18), 5-2 | Fenway Park (9-9) | 12-14 | Lost 2 |
| » Starters: Joe Benz vs Adam Johnson | Sixth | 6½ out |
| Friday, May 22 |
| » Defeated White Sox (14-19), 1-0 | Fenway Park (10-9) | 13-14 | |
| » Starters: Eddie Cicotte vs Rube Foster | Fifth | 5½ out |
| Saturday, May 23 |
| » Defeated White Sox (14-20), 6-2 | Fenway Park (11-9) | 14-14 | Won 2 |
| » Starters: Reb Russell vs Dutch Leonard | Fourth | 4½ out |
| Monday, May 25 |
| » Lost to Indians (10-22), 3-0 | Fenway Park (11-10) | 14-15 | |
| » Starters: Willie Mitchell vs Ray Collins | Fourth | 4½ out |
| Tuesday, May 26 |
| » Lost to Indians (11-22), 3-2 | Fenway Park (11-11) | 14-16 | Lost 2 |
| » Starters: Lefty James vs Rube Foster | Fifth | 5 out |
| Wednesday, May 27 |
| » Defeated Indians (11-23), 5-4 | Fenway Park (12-11) | 15-16 | |
| » Starters: Rip Hagerman vs Joe Wood | Fifth | 5 out |
| Thursday, May 28 |
| » Lost to Indians (12-23), 5-2 | Fenway Park (12-12) | 15-17 | |
| » Starters: Rip Hagerman vs Hugh Bedient | Sixth | 5 out |
| Friday, May 29 |
| » Lost to Senators (22-13), 1-0 | Fenway Park (12-13) | 15-18 | Lost 2 |
| » Starters: Walter Johnson vs Adam Johnson | Fourth | 5 out |
| » Defeated Senators (22-14), 6-5 | Fenway Park (13-13) | 16-18 | |
| » Starters: Joe Boehling vs Dutch Leonard | Fourth | 5 out |
| Saturday, May 30 |
| » Lost to Senators (23-14), 6-4 | Fenway Park (13-14) | 16-19 | |
| » Starters: Doc Ayers vs Dutch Leonard | Fourth | 5 out |
| » Defeated Senators (23-15), 7-2 | Fenway Park (14-14) | 17-19 | |
| » Starters: Jim Shaw vs Hugh Bedient | Fourth | 5 out |
| Monday, June 1 |
| » Defeated Senators (23-16), 1-0 | Fenway Park (15-14) | 18-19 | Won 2 |
| » Starters: Walter Johnson vs Adam Johnson | Fifth | 4½ out |
| Tuesday, June 2 |
| » Defeated Athletics (22-15), 3-2 | Fenway Park (16-14) | 19-19 | Won 3 |
| » Starters: Bullet Joe Bush vs Dutch Leonard | Fifth | 4½ out |
| » Lost to Athletics (23-15), 4-2 | Fenway Park (16-15) | 19-20 | |
| » Starters: Herb Pennock vs Rube Foster | Fifth | 4½ out |
| Wednesday, June 3 |
| » Lost to Athletics (24-15), 10-1 | Fenway Park (16-16) | 19-21 | Lost 2 |
| » Starters: Weldon Wyckoff vs Ray Collins | Fifth | 6½ out |
| » Lost to Athletics (25-15), 7-5 | Fenway Park (16-17) | 19-22 | Lost 3 |
| » Starters: Bob Shawkey vs Hugh Bedient | Fifth | 6½ out |
| Saturday, June 6 |
| » Defeated Indians (14-29), 4-3 | League Park II (1-0) | 20-22 | |
| » Starters: Adam Johnson vs Willie Mitchell | Fifth | 6½ out |
| Sunday, June 7 |
| » Defeated Indians (14-30), 2-1 | League Park II (2-0) | 21-22 | Won 2 |
| » Starters: Rube Foster vs Lefty James | Fifth | 5½ out |
| Monday, June 8 |
| » Defeated Indians (14-31), 11-8 | League Park II (3-0) | 22-22 | Won 3 |
| » Starters: Hugh Bedient vs Abe Bowman | Fifth | 4½ out |
| Tuesday, June 9 |
| » Defeated Indians (14-32), 9-6 | League Park II (4-0) | 23-22 | Won 4 |
| » Starters: Guy Cooper vs Allan Collamore | Fifth | 4½ out |
| Wednesday, June 10 |
| » Defeated Tigers (28-22), 8-2 | Tiger Stadium (1-0) | 24-22 | Won 5 |
| » Starters: Ray Collins vs Alex Main | Fifth | 4½ out |
| Thursday, June 11 |
| » Lost to Tigers (29-22), 2-1 | Tiger Stadium (1-1) | 24-23 | |
| » Starters: Rube Foster vs Hooks Dauss | Fifth | 4½ out |
| Friday, June 12 |
| » Lost to Tigers (30-22), 1-0 | Tiger Stadium (1-2) | 24-24 | Lost 2 |
| » Starters: Adam Johnson vs Harry Coveleski | Fifth | 5½ out |
| Saturday, June 13 |
| » Defeated Tigers (30-23), 8-6 | Tiger Stadium (2-2) | 25-24 | |
| » Starters: Hugh Bedient vs Pug Cavet | Fifth | 5½ out |
| Sunday, June 14 |
| » Defeated Browns (28-23), 10-1 | Sportsman's Park III (1-0) | 26-24 | Won 2 |
| » Starters: Dutch Leonard vs Earl Hamilton | Fifth | 5½ out |
| Monday, June 15 |
| » Defeated Browns (28-24), 2-0 | Sportsman's Park III (2-0) | 27-24 | Won 3 |
| » Starters: Joe Wood vs Walt Leverenz | Fifth | 5½ out |
| Tuesday, June 16 |
| » Defeated Browns (28-25), 2-0 | Sportsman's Park III (3-0) | 28-24 | Won 4 |
| » Starters: Rube Foster vs Carl Weilman | Fourth | 5½ out |
| Future Red Sox Johnnie Wittig is born in Baltimore, MD. |
| Wednesday, June 17 |
| » Lost to Browns (29-25), 4-0 | Sportsman's Park III (3-1) | 28-25 | |
| » Starters: Adam Johnson vs Earl Hamilton | Fifth | 5½ out |
| Thursday, June 18 |
| » Defeated White Sox (24-31), 8-0 | Comiskey Park I (1-0) | 29-25 | |
| » Starters: Dutch Leonard vs Jim Scott | Fourth | 4½ out |
| Friday, June 19 |
| » Lost to White Sox (25-31), 3-2 | Comiskey Park I (1-1) | 29-26 | |
| » Starters: Ray Collins vs Joe Benz | Fourth | 4½ out |
| Saturday, June 20 |
| » Lost to White Sox (26-31), 5-2 | Comiskey Park I (1-2) | 29-27 | Lost 2 |
| » Starters: Joe Wood vs Reb Russell | Fourth | 5½ out |
| Sunday, June 21 |
| » Lost to White Sox (27-31), 5-3 | Comiskey Park I (1-3) | 29-28 | Lost 3 |
| » Starters: Rube Foster vs Red Faber | Fifth | 5½ out |
| Monday, June 22 |
| » Lost to White Sox (28-31), 5-4 | Comiskey Park I (1-4) | 29-29 | Lost 4 |
| » Starters: Hugh Bedient vs Jim Scott | Fifth | 6½ out |
| Wednesday, June 24 |
| » Defeated Yankees (20-34), 3-0 | Polo Grounds V (1-2) | 30-29 | |
| » Starters: Dutch Leonard vs Marty McHale | Fifth | 5½ out |
| » Lost to Yankees (21-34), 3-2 | Polo Grounds V (1-3) | 30-30 | |
| » Starters: Rube Foster vs Ray Keating | Fifth | 5½ out |
| Thursday, June 25 |
| » Lost to Yankees (22-34), 3-2 | Polo Grounds V (1-4) | 30-31 | Lost 2 |
| » Starters: Ray Collins vs Jack Warhop | Fifth | 5½ out |
| » Defeated Yankees (22-35), 4-3 | Polo Grounds V (2-4) | 31-31 | |
| » Starters: Adam Johnson vs Ray Caldwell | Fifth | 5½ out |
| Friday, June 26 |
| » Defeated Yankees (22-36), 2-1 | Polo Grounds V (3-4) | 32-31 | Won 2 |
| » Starters: Fritz Coumbe vs Ray Fisher | Fifth | 5½ out |
| Saturday, June 27 |
| » Defeated Yankees (22-37), 5-3 | Polo Grounds V (4-4) | 33-31 | Won 3 |
| » Starters: Joe Wood vs Marty McHale | Fifth | 5½ out |
| Monday, June 29 |
| » Defeated Athletics (37-25), 7-1 | Shibe Park (2-2) | 34-31 | Won 4 |
| » Starters: Dutch Leonard vs Bullet Joe Bush | Fifth | 5½ out |
| » Lost to Athletics (38-25), 7-2 | Shibe Park (2-3) | 34-32 | |
| » Starters: Adam Johnson vs Eddie Plank | Fifth | 5½ out |
| Tuesday, June 30 |
| » Defeated Athletics (38-26), 5-3 | Shibe Park (3-3) | 35-32 | |
| » Starters: Ray Collins vs Weldon Wyckoff | Fifth | 4½ out |
| Thursday, July 2 |
| » Defeated Athletics (38-27), 7-6 | Shibe Park (4-3) | 36-32 | Won 2 |
| » Starters: Dutch Leonard vs Bob Shawkey | Fourth | 2½ out |
| » Defeated Athletics (38-28), 7-1 | Shibe Park (5-3) | 37-32 | Won 3 |
| » Starters: Fritz Coumbe vs Herb Pennock | Fourth | 2½ out |
| Friday, July 3 |
| » Lost to Senators (37-30), 12-0 | Griffith Stadium (2-2) | 37-33 | |
| » Starters: Adam Johnson vs Walter Johnson | Fourth | 3½ out |
| » Defeated Senators (37-31), 3-1 | Griffith Stadium (3-2) | 38-33 | |
| » Starters: Joe Wood vs Joe Boehling | Fourth | 3½ out |
| Future Red Sox Buddy Rosar is born in Buffalo, NY. |
| Saturday, July 4 |
| » Defeated Senators (37-32), 1-0 | Griffith Stadium (4-2) | 39-33 | Won 2 |
| » Starters: Ray Collins vs Joe Engel | Fourth | 3½ out |
| » Lost to Senators (38-32), 3-2 | Griffith Stadium (4-3) | 39-34 | |
| » Starters: Hugh Bedient vs Jim Shaw | Fourth | 3½ out |
| Monday, July 6 |
| » Lost to Senators (39-32), 1-0 | Griffith Stadium (4-4) | 39-35 | Lost 2 |
| » Starters: Adam Johnson vs Walter Johnson | Fifth | 4½ out |
| Wednesday, July 8 |
| » Lost to White Sox (39-33), 4-2 | Fenway Park (16-18) | 39-36 | Lost 3 |
| » Starters: Reb Russell vs Dutch Leonard | Fifth | 6 out |
| » Lost to White Sox (40-33), 5-4 | Fenway Park (16-19) | 39-37 | Lost 4 |
| » Starters: Joe Benz vs Fritz Coumbe | Fifth | 6 out |
| Thursday, July 9 |
| » Lost to White Sox (41-33), 3-2 | Fenway Park (16-20) | 39-38 | Lost 5 |
| » Starters: Eddie Cicotte vs Ray Collins | Sixth | 5½ out |
| Friday, July 10 |
| » Defeated White Sox (41-34), 5-1 | Fenway Park (17-20) | 40-38 | |
| » Starters: Jim Scott vs Adam Johnson | Fifth | 5 out |
| Saturday, July 11 |
| » Defeated Indians (26-50), 4-3 | Fenway Park (18-20) | 41-38 | Won 2 |
| » Starters: Willie Mitchell vs Babe Ruth | Sixth | 4½ out |
| Monday, July 13 |
| » Defeated Indians (26-51), 2-0 | Fenway Park (19-20) | 42-38 | Won 3 |
| » Starters: Guy Morton vs Ray Collins | Fifth | 4 out |
| Tuesday, July 14 |
| » Defeated Indians (26-52), 2-1 | Fenway Park (20-20) | 43-38 | Won 4 |
| » Starters: Bill Steen vs Ernie Shore | Fifth | 3½ out |
| Wednesday, July 15 |
| » Defeated Indians (26-53), 4-0 | Fenway Park (21-20) | 44-38 | Won 5 |
| » Starters: Vean Gregg vs Dutch Leonard | Fifth | 3 out |
| Thursday, July 16 |
| » Lost to Tigers (46-37), 5-2 | Fenway Park (21-21) | 44-39 | |
| » Starters: Hooks Dauss vs Babe Ruth | Fifth | 4 out |
| Friday, July 17 |
| » Defeated Tigers (46-38), 8-2 | Fenway Park (22-21) | 45-39 | |
| » Starters: Harry Coveleski vs Ray Collins | Fourth | 3½ out |
| Saturday, July 18 |
| » Lost to Tigers (47-38), 4-2 | Fenway Park (22-22) | 45-40 | |
| » Starters: Jean Dubuc vs Ernie Shore | Fourth | 5 out |
| Monday, July 20 |
| » Defeated Tigers (47-39), 3-2 | Fenway Park (23-22) | 46-40 | |
| » Starters: Hooks Dauss vs Fritz Coumbe | Fourth | 5 out |
| Tuesday, July 21 |
| » Tied Browns, 1-1 | Fenway Park (23-22) | 46-40 | |
| » Starters: Walt Leverenz vs Ray Collins | Fourth | 6 out |
| Wednesday, July 22 |
| » Defeated Browns (44-41), 5-3 | Fenway Park (24-22) | 47-40 | Won 2 |
| » Starters: Earl Hamilton vs Rube Foster | Second | 5½ out |
| » Defeated Browns (44-42), 6-2 | Fenway Park (25-22) | 48-40 | Won 3 |
| » Starters: Bill James vs Ernie Shore | Second | 5½ out |
| Saturday, July 25 |
| » Defeated Indians (29-59), 8-6 | League Park II (5-0) | 49-40 | Won 4 |
| » Starters: Dutch Leonard vs Vean Gregg | Second | 6 out |
| Sunday, July 26 |
| » Defeated Indians (29-60), 4-1 | League Park II (6-0) | 50-40 | Won 5 |
| » Starters: Ernie Shore vs Guy Morton | Second | 6 out |
| Future Red Sox Ellis Kinder is born in Atkins, AR. |
| Monday, July 27 |
| » Defeated Indians (29-61), 3-0 | League Park II (7-0) | 51-40 | Won 6 |
| » Starters: Dutch Leonard vs Bill Steen | Second | 6 out |
| Tuesday, July 28 |
| » Lost to Indians (30-61), 4-3 | League Park II (7-1) | 51-41 | |
| » Starters: Ray Collins vs Willie Mitchell | Second | 6 out |
| Wednesday, July 29 |
| » Defeated White Sox (47-46), 8-4 | Comiskey Park I (2-4) | 52-41 | |
| » Starters: Vean Gregg vs Eddie Cicotte | Second | 6 out |
| Thursday, July 30 |
| » Defeated White Sox (47-47), 4-0 | Comiskey Park I (3-4) | 53-41 | Won 2 |
| » Starters: Ernie Shore vs Joe Benz | Second | 6 out |
| Friday, July 31 |
| » Defeated White Sox (47-48), 5-1 | Comiskey Park I (4-4) | 54-41 | Won 3 |
| » Starters: Dutch Leonard vs Red Faber | Second | 6 out |
| Saturday, August 1 |
| » Defeated White Sox (47-49), 4-2 | Comiskey Park I (5-4) | 55-41 | Won 4 |
| » Starters: Ray Collins vs Joe Benz | Second | 6 out |
| Sunday, August 2 |
| » Lost to Browns (46-49), 1-0 | Sportsman's Park III (3-2) | 55-42 | |
| » Starters: Rube Foster vs Carl Weilman | Second | 7 out |
| Monday, August 3 |
| » Lost to Browns (47-49), 6-1 | Sportsman's Park III (3-3) | 55-43 | Lost 2 |
| » Starters: Vean Gregg vs Bill James | Second | 7 out |
| Tuesday, August 4 |
| » Lost to Browns (48-49), 2-1 | Sportsman's Park III (3-4) | 55-44 | Lost 3 |
| » Starters: Ernie Shore vs Earl Hamilton | Third | 8 out |
| Wednesday, August 5 |
| » Defeated Browns (48-50), 6-0 | Sportsman's Park III (4-4) | 56-44 | |
| » Starters: Dutch Leonard vs Walt Leverenz | Second | 8 out |
| Friday, August 7 |
| » Lost to Tigers (53-49), 3-1 | Tiger Stadium (2-3) | 56-45 | |
| » Starters: Vean Gregg vs Harry Coveleski | Second | 9 out |
| Saturday, August 8 |
| » Defeated Tigers (53-50), 5-2 | Tiger Stadium (3-3) | 57-45 | |
| » Starters: Joe Wood vs Pug Cavet | Second | 9 out |
| Sunday, August 9 |
| » Defeated Tigers (53-51), 8-6 | Tiger Stadium (4-3) | 58-45 | Won 2 |
| » Starters: Ernie Shore vs Alex Main | Second | 9 out |
| Thursday, August 13 |
| » Lost to Yankees (47-58), 1-0 | Fenway Park (25-23) | 58-46 | |
| » Starters: Ray Fisher vs Dutch Leonard | Second | 10½ out |
| Friday, August 14 |
| » Lost to Yankees (48-58), 7-6 | Fenway Park (25-24) | 58-47 | Lost 2 |
| » Starters: Boardwalk Brown vs Rube Foster | Second | 10½ out |
| Saturday, August 15 |
| » Defeated Yankees (48-59), 1-0 | Fenway Park (26-24) | 59-47 | |
| » Starters: Marty McHale vs Vean Gregg | Second | 10½ out |
| Wednesday, August 19 |
| » Defeated White Sox (55-57), 3-1 | Fenway Park (27-24) | 60-47 | Won 2 |
| » Starters: Joe Benz vs Dutch Leonard | Second | 10½ out |
| » Defeated White Sox (55-58), 4-1 | Fenway Park (28-24) | 61-47 | Won 3 |
| » Starters: Jim Scott vs Joe Wood | Second | 10½ out |
| Thursday, August 20 |
| » Defeated White Sox (55-59), 3-2 | Fenway Park (29-24) | 62-47 | Won 4 |
| » Starters: Mellie Wolfgang vs Ernie Shore | Second | 10½ out |
| Saturday, August 22 |
| » Defeated Indians (38-80), 4-2 | Fenway Park (30-24) | 63-47 | Won 5 |
| » Starters: Guy Morton vs Rube Foster | Second | 10 out |
| Monday, August 24 |
| » Defeated Indians (38-81), 7-3 | Fenway Park (31-24) | 64-47 | Won 6 |
| » Starters: Rip Hagerman vs Dutch Leonard | Second | 10½ out |
| Tuesday, August 25 |
| » Lost to Indians (39-81), 3-1 | Fenway Park (31-25) | 64-48 | |
| » Starters: Willie Mitchell vs Ernie Shore | Second | 12 out |
| Wednesday, August 26 |
| » Defeated Tigers (59-58), 5-2 | Fenway Park (32-25) | 65-48 | |
| » Starters: Red Oldham vs Vean Gregg | Second | 12 out |
| Thursday, August 27 |
| » Defeated Tigers (59-59), 9-2 | Fenway Park (33-25) | 66-48 | Won 2 |
| » Starters: Jean Dubuc vs Ray Collins | Second | 12 out |
| » Major-league debuts: Fred McMullin (Tigers) |
| Friday, August 28 |
| » Lost to Tigers (60-59), 3-0 | Fenway Park (33-26) | 66-49 | |
| » Starters: Pug Cavet vs Dutch Leonard | Second | 12 out |
| Monday, August 31 |
| » Defeated Browns (55-64), 4-1 | Fenway Park (34-26) | 67-49 | |
| » Starters: Bill James vs Rube Foster | Second | 12½ out |
| » Tied Browns, 3-3 | Fenway Park (34-26) | 67-49 | |
| » Starters: Earl Hamilton vs Joe Wood | Second | 12½ out |
| Tuesday, September 1 |
| » Defeated Browns (55-65), 7-6 | Fenway Park (35-26) | 68-49 | Won 2 |
| » Starters: Carl Weilman vs Ray Collins | Second | 12 out |
| » Defeated Browns (55-66), 4-2 | Fenway Park (36-26) | 69-49 | Won 3 |
| » Starters: Walt Leverenz vs Ernie Shore | Second | 12 out |
| Wednesday, September 2 |
| » Lost to Browns (56-66), 9-6 | Fenway Park (36-27) | 69-50 | |
| » Starters: George Baumgardner vs Vean Gregg | Second | 12 out |
| » Defeated Browns (56-67), 7-3 | Fenway Park (37-27) | 70-50 | |
| » Starters: Roy Mitchell vs Hugh Bedient | Second | 12 out |
| Thursday, September 3 |
| » Defeated Athletics (82-39), 3-1 | Fenway Park (38-27) | 71-50 | Won 2 |
| » Starters: Eddie Plank vs Rube Foster | Second | 10 out |
| » Defeated Athletics (82-40), 6-3 | Fenway Park (39-27) | 72-50 | Won 3 |
| » Starters: Bob Shawkey vs Joe Wood | Second | 10 out |
| Friday, September 4 |
| » Defeated Athletics (82-41), 4-2 | Fenway Park (40-27) | 73-50 | Won 4 |
| » Starters: Bullet Joe Bush vs Ray Collins | Second | 9 out |
| Saturday, September 5 |
| » Defeated Athletics (82-42), 4-1 | Fenway Park (41-27) | 74-50 | Won 5 |
| » Starters: Rube Bressler vs Ernie Shore | Second | 8 out |
| Monday, September 7 |
| » Defeated Yankees (57-70), 5-1 | Polo Grounds V (5-4) | 75-50 | Won 6 |
| » Starters: Rube Foster vs Marty McHale | Second | 8 out |
| » Lost to Yankees (58-70), 8-1 | Polo Grounds V (5-5) | 75-51 | |
| » Starters: Joe Wood vs Ray Keating | Second | 8 out |
| Tuesday, September 8 |
| » Defeated Yankees (58-71), 6-5 | Polo Grounds V (6-5) | 76-51 | |
| » Starters: Vean Gregg vs Ray Fisher | Second | 7½ out |
| Wednesday, September 9 |
| » Defeated Athletics (84-45), 2-0 | Shibe Park (6-3) | 77-51 | Won 2 |
| » Starters: Ray Collins vs Eddie Plank | Second | 6½ out |
| Thursday, September 10 |
| » Lost to Athletics (85-45), 8-1 | Shibe Park (6-4) | 77-52 | |
| » Starters: Rube Foster vs Rube Bressler | Second | 7½ out |
| Friday, September 11 |
| » Tied Athletics, 8-8 | Shibe Park (6-4) | 77-52 | |
| » Starters: Joe Wood vs Herb Pennock | Second | 7½ out |
| Monday, September 14 |
| » Lost to Senators (68-60), 8-1 | Griffith Stadium (4-5) | 77-53 | Lost 2 |
| » Starters: Ernie Shore vs Walter Johnson | Second | 7½ out |
| » Defeated Senators (68-61), 3-0 | Griffith Stadium (5-5) | 78-53 | |
| » Starters: Ray Collins vs Jack Bentley | Second | 7½ out |
| Tuesday, September 15 |
| » Defeated Senators (68-62), 2-1 | Griffith Stadium (6-5) | 79-53 | Won 2 |
| » Starters: Joe Wood vs Jim Shaw | Second | 7½ out |
| Thursday, September 17 |
| » Defeated Indians (43-93), 8-1 | League Park II (8-1) | 80-53 | Won 3 |
| » Starters: Rube Foster vs Willie Mitchell | Second | 7½ out |
| » Major-league debuts: Walter Barbare (Indians) |
| Friday, September 18 |
| » Defeated Indians (43-94), 4-3 | League Park II (9-1) | 81-53 | Won 4 |
| » Starters: Ernie Shore vs Bill Steen | Second | 6½ out |
| Saturday, September 19 |
| » Lost to Indians (44-94), 5-1 | League Park II (9-2) | 81-54 | |
| » Starters: Ray Collins vs Al Tedrow | Second | 6½ out |
| Sunday, September 20 |
| » Defeated Tigers (75-65), 10-3 | Tiger Stadium (5-3) | 82-54 | |
| » Starters: Vean Gregg vs Ross Reynolds | Second | 6 out |
| » Defeated Tigers (75-66), 7-2 | Tiger Stadium (6-3) | 83-54 | Won 2 |
| » Starters: Joe Wood vs Red Oldham | Second | 6 out |
| Monday, September 21 |
| » Tied Tigers, 8-8 | Tiger Stadium (6-3) | 83-54 | |
| » Starters: Rube Foster vs Hooks Dauss | Second | 5½ out |
| Tuesday, September 22 |
| » Defeated Tigers (75-67), 5-3 | Tiger Stadium (7-3) | 84-54 | Won 3 |
| » Starters: Ray Collins vs Harry Coveleski | Second | 5 out |
| » Defeated Tigers (75-68), 5-0 | Tiger Stadium (8-3) | 85-54 | Won 4 |
| » Starters: Ray Collins vs Red Oldham | Second | 5 out |
| Thursday, September 24 |
| » Defeated Browns (63-78), 5-1 | Sportsman's Park III (5-4) | 86-54 | Won 5 |
| » Starters: Rube Foster vs Bill James | Second | 5 out |
| Friday, September 25 |
| » Lost to Browns (64-78), 10-1 | Sportsman's Park III (5-5) | 86-55 | |
| » Starters: Ernie Shore vs Earl Hamilton | Second | 6 out |
| Saturday, September 26 |
| » Lost to Browns (65-78), 4-1 | Sportsman's Park III (5-6) | 86-56 | Lost 2 |
| » Starters: Vean Gregg vs Carl Weilman | Second | 7½ out |
| » Lost to Browns (66-78), 6-4 | Sportsman's Park III (5-7) | 86-57 | Lost 3 |
| » Starters: Joe Wood vs Walt Leverenz | Second | 7½ out |
| Sunday, September 27 |
| » Defeated White Sox (67-79), 8-6 | Comiskey Park I (6-4) | 87-57 | |
| » Starters: Ray Collins vs Red Faber | Second | 8 out |
| » Lost to White Sox (68-79), 4-3 | Comiskey Park I (6-5) | 87-58 | |
| » Starters: Hugh Bedient vs Joe Benz | Second | 8 out |
| Monday, September 28 |
| » Defeated White Sox (68-80), 5-2 | Comiskey Park I (7-5) | 88-58 | |
| » Starters: Ernie Shore vs Bill Lathrop | Second | 7 out |
| Thursday, October 1 |
| » Lost to Yankees (68-80), 5-3 | Fenway Park (41-28) | 88-59 | |
| » Starters: Jack Warhop vs Rube Foster | Second | 8 out |
| » Defeated Yankees (68-81), 4-2 | Fenway Park (42-28) | 89-59 | |
| » Starters: Marty McHale vs Hugh Bedient | Second | 8 out |
| Friday, October 2 |
| » Defeated Yankees (68-82), 11-5 | Fenway Park (43-28) | 90-59 | Won 2 |
| » Starters: Boardwalk Brown vs Babe Ruth | Second | 7 out |
| Saturday, October 3 |
| » Lost to Yankees (69-82), 3-2 | Fenway Park (43-29) | 90-60 | |
| » Starters: Ray Fisher vs Ernie Shore | Second | 7 out |
| Monday, October 5 |
| » Lost to Senators (80-71), 9-3 | Fenway Park (43-30) | 90-61 | Lost 2 |
| » Starters: Walter Johnson vs Ray Collins | Second | 8 out |
| Tuesday, October 6 |
| » Defeated Senators (80-72), 8-4 | Fenway Park (44-30) | 91-61 | |
| » Starters: Jim Shaw vs Rube Foster | Second | 7 out |
| Wednesday, October 7 |
| » Lost to Senators (81-72), 11-4 | Fenway Park (44-31) | 91-62 | |
| » Starters: Jack Bentley vs Hugh Bedient | Second | 8 out |
| Saturday, October 10 |
| Future Red Sox Tommy Fine is born in Cleburne, TX. |
| Tuesday, October 13 |
| Future Red Sox Frankie Hayes is born in Jamesburg, NJ. |
| Monday, November 2 |
| Future Red Sox Tom McBride is born in Bonham, TX. |
| Thursday, November 12 |
| Future Red Sox Emerson Dickman is born in Buffalo, NY. |
Game information provided by Retrosheet (www.retrosheet.org) |
