| Monday, January 5 |
| Future Indian Jack Salveson is born in Fullerton, CA. |
| Monday, February 23 |
| Future Indian Mike Tresh is born in Hazleton, PA. |
| Tuesday, April 14 |
| » Lost to White Sox (1-0), 5-2 | Comiskey Park I (0-1) | 0-1 | |
| » Starters: Willie Mitchell vs Jim Scott | Second | 1 out |
| » Major-league debuts: Hank Schreiber (White Sox) |
| Wednesday, April 15 |
| » Lost to White Sox (2-0), 2-1 | Comiskey Park I (0-2) | 0-2 | Lost 2 |
| » Starters: Bill Steen vs Eddie Cicotte | Fifth | 2 out |
| Thursday, April 16 |
| » Lost to White Sox (3-0), 1-0 | Comiskey Park I (0-3) | 0-3 | Lost 3 |
| » Starters: Fred Blanding vs Joe Benz | Fifth | 3 out |
| Friday, April 17 |
| » Lost to White Sox (4-0), 6-5 | Comiskey Park I (0-4) | 0-4 | Lost 4 |
| » Starters: Rip Hagerman vs Red Faber | Sixth | 4 out |
| » Major-league debuts: Red Faber (White Sox) |
| Saturday, April 18 |
| » Lost to Tigers (2-2), 4-3 | Tiger Stadium (0-1) | 0-5 | Lost 5 |
| » Starters: Willie Mitchell vs Marc Hall | Sixth | 5 out |
| » Major-league debuts: Marty Kavanagh and Miles Main (Tigers) |
| Sunday, April 19 |
| » Lost to Tigers (3-2), 7-6 | Tiger Stadium (0-2) | 0-6 | Lost 6 |
| » Starters: George Kahler vs George Boehler | Seventh | 5 out |
| Monday, April 20 |
| » Major-league debuts: Rankin Johnson (Red Sox) |
| Tuesday, April 21 |
| » Lost to Tigers (4-2), 7-4 | Tiger Stadium (0-3) | 0-7 | Lost 7 |
| » Starters: Rip Hagerman vs Johnnie Williams | Eighth | 6 out |
| Wednesday, April 22 |
| » Lost to White Sox (7-1), 7-0 | League Park II (0-1) | 0-8 | Lost 8 |
| » Starters: Reb Russell vs Fred Blanding | Eighth | 7 out |
| Thursday, April 23 |
| » Defeated White Sox (7-2), 4-1 | League Park II (1-1) | 1-8 | |
| » Starters: Eddie Cicotte vs Willie Mitchell | Eighth | 6 out |
| Saturday, April 25 |
| » Defeated White Sox (7-3), 1-0 | League Park II (2-1) | 2-8 | Won 2 |
| » Starters: Joe Benz vs Rip Hagerman | Sixth | 5 out |
| Sunday, April 26 |
| » Defeated White Sox (7-4), 4-2 | League Park II (3-1) | 3-8 | Won 3 |
| » Starters: Jim Scott vs Fred Blanding | Sixth | 4 out |
| Wednesday, April 29 |
| » Lost to Browns (6-6), 6-3 | Sportsman's Park III (0-1) | 3-9 | |
| » Starters: Willie Mitchell vs Bill James | Eighth | 5½ out |
| Thursday, April 30 |
| » Tied Browns, 3-3 | Sportsman's Park III (0-1) | 3-9 | |
| » Starters: Willie Mitchell vs George Baumgardner | Eighth | 6 out |
| Friday, May 1 |
| » Lost to Browns (7-6), 3-2 | Sportsman's Park III (0-2) | 3-10 | Lost 2 |
| » Starters: Rip Hagerman vs Wiley Taylor | Eighth | 7 out |
| Saturday, May 2 |
| » Defeated Tigers (11-5), 3-0 | League Park II (4-1) | 4-10 | |
| » Starters: Harry Coveleski vs Vean Gregg | Eighth | 6 out |
| Sunday, May 3 |
| » Lost to Tigers (12-5), 9-5 | League Park II (4-2) | 4-11 | |
| » Starters: Alex Main vs Lefty James | Eighth | 7 out |
| Monday, May 4 |
| » Lost to Tigers (13-5), 9-7 | League Park II (4-3) | 4-12 | Lost 2 |
| » Starters: Jean Dubuc vs Lefty James | Eighth | 8 out |
| Tuesday, May 5 |
| » Defeated Tigers (13-6), 4-2 | League Park II (5-3) | 5-12 | |
| » Starters: Harry Coveleski vs Rip Hagerman | Seventh | 7 out |
| Wednesday, May 6 |
| » Lost to Browns (10-8), 7-1 | League Park II (5-4) | 5-13 | |
| » Starters: Bill James vs Fred Blanding | Seventh | 8 out |
| Thursday, May 7 |
| » Lost to Browns (11-8), 2-0 | League Park II (5-5) | 5-14 | Lost 2 |
| » Starters: Earl Hamilton vs Willie Mitchell | Seventh | 8½ out |
| Saturday, May 9 |
| » Defeated Browns (11-9), 6-5 | League Park II (6-5) | 6-14 | |
| » Starters: George Baumgardner vs Vean Gregg | Eighth | 9 out |
| Sunday, May 10 |
| » Defeated Browns (11-10), 4-0 | League Park II (7-5) | 7-14 | Won 2 |
| » Starters: Bill James vs Rip Hagerman | Eighth | 8 out |
| Tuesday, May 12 |
| » Defeated Athletics (10-8), 12-4 | Shibe Park (1-0) | 8-14 | Won 3 |
| » Starters: Willie Mitchell vs Bullet Joe Bush | Eighth | 8 out |
| Thursday, May 14 |
| » Lost to Athletics (11-8), 1-0 | Shibe Park (1-1) | 8-15 | |
| » Starters: Rip Hagerman vs Eddie Plank | Eighth | 9 out |
| Friday, May 15 |
| » Lost to Athletics (12-8), 6-3 | Shibe Park (1-2) | 8-16 | Lost 2 |
| » Starters: Fred Blanding vs Bob Shawkey | Eighth | 10 out |
| Future Indian Jimmy Wasdell is born in Cleveland, OH. |
| Saturday, May 16 |
| » Lost to Senators (13-11), 2-1 | Griffith Stadium (0-1) | 8-17 | Lost 3 |
| » Starters: Fred Blanding vs Walter Johnson | Eighth | 10 out |
| Monday, May 18 |
| » Lost to Senators (14-11), 3-2 | Griffith Stadium (0-2) | 8-18 | Lost 4 |
| » Starters: Rip Hagerman vs Doc Ayers | Seventh | 10 out |
| Tuesday, May 19 |
| » Lost to Senators (15-11), 4-2 | Griffith Stadium (0-3) | 8-19 | Lost 5 |
| » Starters: Willie Mitchell vs Jim Shaw | Eighth | 10 out |
| » Major-league debuts: Abe Bowman (Indians) |
| Wednesday, May 20 |
| » Lost to Senators (16-11), 5-0 | Griffith Stadium (0-4) | 8-20 | Lost 6 |
| » Starters: Vean Gregg vs Walter Johnson | Seventh | 11 out |
| Future Indian Stan Benjamin is born in Framingham, MA. |
| Thursday, May 21 |
| » Lost to Yankees (13-13), 5-2 | Polo Grounds V (0-1) | 8-21 | Lost 7 |
| » Starters: Allan Collamore vs Ray Fisher | Eighth | 12 out |
| Friday, May 22 |
| » Defeated Yankees (13-14), 3-2 | Polo Grounds V (1-1) | 9-21 | |
| » Starters: Rip Hagerman vs Marty McHale | Seventh | 11 out |
| Saturday, May 23 |
| » Lost to Yankees (14-14), 10-9 | Polo Grounds V (1-2) | 9-22 | |
| » Starters: Willie Mitchell vs Ray Keating | Seventh | 11 out |
| Monday, May 25 |
| » Defeated Red Sox (14-15), 3-0 | Fenway Park (1-0) | 10-22 | |
| » Starters: Willie Mitchell vs Ray Collins | Seventh | 10 out |
| Tuesday, May 26 |
| » Defeated Red Sox (14-16), 3-2 | Fenway Park (2-0) | 11-22 | Won 2 |
| » Starters: Lefty James vs Rube Foster | Seventh | 9½ out |
| Wednesday, May 27 |
| » Lost to Red Sox (15-16), 5-4 | Fenway Park (2-1) | 11-23 | |
| » Starters: Rip Hagerman vs Joe Wood | Eighth | 10½ out |
| Thursday, May 28 |
| » Defeated Red Sox (15-17), 5-2 | Fenway Park (3-1) | 12-23 | |
| » Starters: Rip Hagerman vs Hugh Bedient | Eighth | 9½ out |
| Saturday, May 30 |
| » Lost to White Sox (17-21), 6-3 | League Park II (7-6) | 12-24 | |
| » Starters: Eddie Cicotte vs Willie Mitchell | Seventh | 9½ out |
| » Defeated White Sox (17-22), 2-1 | League Park II (8-6) | 13-24 | |
| » Starters: Reb Russell vs Bill Steen | Seventh | 9½ out |
| Sunday, May 31 |
| » Lost to White Sox (18-22), 6-1 | Comiskey Park I (0-5) | 13-25 | |
| » Starters: Abe Bowman vs Joe Benz | Eighth | 10 out |
| Monday, June 1 |
| » Lost to Browns (19-19), 10-5 | League Park II (8-7) | 13-26 | Lost 2 |
| » Starters: Bill James vs Vean Gregg | Eighth | 10½ out |
| Tuesday, June 2 |
| » Lost to Browns (20-19), 3-0 | League Park II (8-8) | 13-27 | Lost 3 |
| » Starters: Wiley Taylor vs Rip Hagerman | Eighth | 11 out |
| Wednesday, June 3 |
| » Defeated White Sox (18-25), 6-2 | Comiskey Park I (1-5) | 14-27 | |
| » Starters: Lefty James vs Eddie Cicotte | Eighth | 11½ out |
| Thursday, June 4 |
| » Lost to White Sox (19-25), 2-0 | Comiskey Park I (1-6) | 14-28 | |
| » Starters: Fred Blanding vs Jim Scott | Eighth | 12 out |
| Saturday, June 6 |
| » Lost to Red Sox (20-22), 4-3 | League Park II (8-9) | 14-29 | Lost 2 |
| » Starters: Adam Johnson vs Willie Mitchell | Eighth | 13 out |
| Sunday, June 7 |
| » Lost to Red Sox (21-22), 2-1 | League Park II (8-10) | 14-30 | Lost 3 |
| » Starters: Rube Foster vs Lefty James | Eighth | 13 out |
| Monday, June 8 |
| » Lost to Red Sox (22-22), 11-8 | League Park II (8-11) | 14-31 | Lost 4 |
| » Starters: Hugh Bedient vs Abe Bowman | Eighth | 13 out |
| Tuesday, June 9 |
| » Lost to Red Sox (23-22), 9-6 | League Park II (8-12) | 14-32 | Lost 5 |
| » Starters: Guy Cooper vs Allan Collamore | Eighth | 14 out |
| Wednesday, June 10 |
| » Lost to Athletics (28-17), 8-0 | League Park II (8-13) | 14-33 | Lost 6 |
| » Starters: Bullet Joe Bush vs Willie Mitchell | Eighth | 15 out |
| Thursday, June 11 |
| » Defeated Athletics (28-18), 3-0 | League Park II (9-13) | 15-33 | |
| » Starters: Herb Pennock vs Bill Steen | Eighth | 14 out |
| Friday, June 12 |
| » Lost to Athletics (29-18), 6-1 | League Park II (9-14) | 15-34 | |
| » Starters: Weldon Wyckoff vs Allan Collamore | Eighth | 15 out |
| Saturday, June 13 |
| » Lost to Athletics (30-18), 10-8 | League Park II (9-15) | 15-35 | Lost 2 |
| » Starters: Bob Shawkey vs Rip Hagerman | Eighth | 16 out |
| » Major-league debuts: Sad Sam Jones (Indians) |
| Sunday, June 14 |
| » Defeated Senators (29-21), 4-0 | League Park II (10-15) | 16-35 | |
| » Starters: Walter Johnson vs Abe Bowman | Eighth | 16 out |
| Monday, June 15 |
| » Defeated Senators (29-22), 7-6 | League Park II (11-15) | 17-35 | Won 2 |
| » Starters: Joe Boehling vs Bill Steen | Eighth | 16 out |
| Tuesday, June 16 |
| » Defeated Senators (29-23), 2-1 | League Park II (12-15) | 18-35 | Won 3 |
| » Starters: Doc Ayers vs Bill Steen | Eighth | 16 out |
| Wednesday, June 17 |
| » Defeated Senators (29-24), 7-2 | League Park II (13-15) | 19-35 | Won 4 |
| » Starters: Jim Shaw vs Allan Collamore | Eighth | 15 out |
| Saturday, June 20 |
| » Lost to Yankees (20-32), 7-1 | League Park II (13-16) | 19-36 | |
| » Starters: Ray Caldwell vs Abe Bowman | Seventh | 15 out |
| » Major-league debuts: Guy Morton (Indians) |
| Sunday, June 21 |
| » Defeated Yankees (20-33), 7-3 | League Park II (14-16) | 20-36 | |
| » Starters: Ray Fisher vs Bill Steen | Eighth | 14 out |
| Tuesday, June 23 |
| » Defeated Tigers (36-27), 5-4 | Tiger Stadium (1-3) | 21-36 | Won 2 |
| » Starters: Willie Mitchell vs Hooks Dauss | Eighth | 14 out |
| Wednesday, June 24 |
| » Lost to Browns (33-27), 5-4 | Sportsman's Park III (0-3) | 21-37 | |
| » Starters: Abe Bowman vs Wiley Taylor | Eighth | 14 out |
| » Lost to Browns (34-27), 3-1 | Sportsman's Park III (0-4) | 21-38 | Lost 2 |
| » Starters: Lefty James vs Carl Weilman | Eighth | 14 out |
| Thursday, June 25 |
| » Defeated Browns (34-28), 6-3 | Sportsman's Park III (1-4) | 22-38 | |
| » Starters: Vean Gregg vs George Baumgardner | Eighth | 13½ out |
| Friday, June 26 |
| » Lost to Browns (35-28), 2-0 | Sportsman's Park III (1-5) | 22-39 | |
| » Starters: Allan Collamore vs Earl Hamilton | Eighth | 14½ out |
| Saturday, June 27 |
| » Defeated Browns (35-29), 16-4 | Sportsman's Park III (2-5) | 23-39 | |
| » Starters: Willie Mitchell vs Walt Leverenz | Eighth | 15 out |
| » Lost to Browns (36-29), 4-3 | Sportsman's Park III (2-6) | 23-40 | |
| » Starters: Bill Steen vs Bill James | Eighth | 15 out |
| Sunday, June 28 |
| » Lost to Tigers (38-30), 6-4 | Tiger Stadium (1-4) | 23-41 | Lost 2 |
| » Starters: Fred Blanding vs Harry Coveleski | Eighth | 15½ out |
| Tuesday, June 30 |
| » Defeated Browns (36-32), 8-3 | League Park II (15-16) | 24-41 | |
| » Starters: Earl Hamilton vs Vean Gregg | Seventh | 15 out |
| » Lost to Browns (37-32), 5-0 | League Park II (15-17) | 24-42 | |
| » Starters: George Baumgardner vs Rip Hagerman | Seventh | 15 out |
| Thursday, July 2 |
| » Lost to Tigers (40-31), 4-0 | Tiger Stadium (1-5) | 24-43 | Lost 2 |
| » Starters: Abe Bowman vs Hooks Dauss | Seventh | 14½ out |
| Friday, July 3 |
| » Lost to Tigers (41-31), 8-2 | Tiger Stadium (1-6) | 24-44 | Lost 3 |
| » Starters: Allan Collamore vs Harry Coveleski | Eighth | 16 out |
| Future Indian Buddy Rosar is born in Buffalo, NY. |
| Saturday, July 4 |
| » Defeated Tigers (41-32), 10-8 | Tiger Stadium (2-6) | 25-44 | |
| » Starters: Vean Gregg vs Jean Dubuc | Eighth | 16 out |
| » Lost to Tigers (42-32), 3-2 | Tiger Stadium (2-7) | 25-45 | |
| » Starters: Bill Steen vs Alex Main | Eighth | 16 out |
| Sunday, July 5 |
| » Lost to White Sox (38-33), 6-3 | Comiskey Park I (1-7) | 25-46 | Lost 2 |
| » Starters: Rip Hagerman vs Ed Walsh | Eighth | 16½ out |
| Wednesday, July 8 |
| » Lost to Yankees (25-44), 7-1 | Polo Grounds V (1-3) | 25-47 | Lost 3 |
| » Starters: Willie Mitchell vs Jack Warhop | Seventh | 18 out |
| Thursday, July 9 |
| » Lost to Yankees (26-44), 7-4 | Polo Grounds V (1-4) | 25-48 | Lost 4 |
| » Starters: Vean Gregg vs Cy Pieh | Eighth | 17½ out |
| » Tied Yankees, 3-3 | Polo Grounds V (1-4) | 25-48 | |
| » Starters: Bill Steen vs Ray Keating | Eighth | 17½ out |
| Friday, July 10 |
| » Defeated Yankees (26-45), 7-2 | Polo Grounds V (2-4) | 26-48 | |
| » Starters: Vean Gregg vs Jack Warhop | Seventh | 17½ out |
| » Lost to Yankees (27-45), 1-0 | Polo Grounds V (2-5) | 26-49 | |
| » Starters: Rip Hagerman vs Ray Caldwell | Seventh | 17½ out |
| Saturday, July 11 |
| » Lost to Red Sox (41-38), 4-3 | Fenway Park (3-2) | 26-50 | Lost 2 |
| » Starters: Willie Mitchell vs Babe Ruth | Eighth | 18 out |
| Monday, July 13 |
| » Lost to Red Sox (42-38), 2-0 | Fenway Park (3-3) | 26-51 | Lost 3 |
| » Starters: Guy Morton vs Ray Collins | Seventh | 18½ out |
| Tuesday, July 14 |
| » Lost to Red Sox (43-38), 2-1 | Fenway Park (3-4) | 26-52 | Lost 4 |
| » Starters: Bill Steen vs Ernie Shore | Eighth | 19 out |
| Wednesday, July 15 |
| » Lost to Red Sox (44-38), 4-0 | Fenway Park (3-5) | 26-53 | Lost 5 |
| » Starters: Vean Gregg vs Dutch Leonard | Eighth | 19½ out |
| Thursday, July 16 |
| » Defeated Senators (43-36), 2-0 | Griffith Stadium (1-4) | 27-53 | |
| » Starters: Rip Hagerman vs Jim Shaw | Eighth | 19½ out |
| Future Indian Don Ross is born in Pasadena, CA. |
| Friday, July 17 |
| » Defeated Senators (43-37), 3-1 | Griffith Stadium (2-4) | 28-53 | Won 2 |
| » Starters: Allan Collamore vs Walter Johnson | Eighth | 19 out |
| Saturday, July 18 |
| » Lost to Senators (44-37), 5-3 | Griffith Stadium (2-5) | 28-54 | |
| » Starters: Guy Morton vs Doc Ayers | Eighth | 20½ out |
| Monday, July 20 |
| » Defeated Senators (44-38), 2-1 | Griffith Stadium (3-5) | 29-54 | |
| » Starters: Vean Gregg vs Joe Boehling | Eighth | 20½ out |
| Tuesday, July 21 |
| » Lost to Athletics (49-32), 2-1 | Shibe Park (1-3) | 29-55 | |
| » Starters: Willie Mitchell vs Bullet Joe Bush | Eighth | 22½ out |
| » Lost to Athletics (50-32), 7-6 | Shibe Park (1-4) | 29-56 | Lost 2 |
| » Starters: Bill Steen vs Rube Bressler | Eighth | 22½ out |
| Wednesday, July 22 |
| » Lost to Athletics (51-32), 3-0 | Shibe Park (1-5) | 29-57 | Lost 3 |
| » Starters: Guy Morton vs Herb Pennock | Seventh | 23½ out |
| Thursday, July 23 |
| » Lost to Athletics (52-32), 9-2 | Shibe Park (1-6) | 29-58 | Lost 4 |
| » Starters: Abe Bowman vs Chief Bender | Eighth | 24½ out |
| Saturday, July 25 |
| » Lost to Red Sox (49-40), 8-6 | League Park II (15-18) | 29-59 | Lost 5 |
| » Starters: Dutch Leonard vs Vean Gregg | Eighth | 25½ out |
| Sunday, July 26 |
| » Lost to Red Sox (50-40), 4-1 | League Park II (15-19) | 29-60 | Lost 6 |
| » Starters: Ernie Shore vs Guy Morton | Eighth | 26½ out |
| Monday, July 27 |
| » Lost to Red Sox (51-40), 3-0 | League Park II (15-20) | 29-61 | Lost 7 |
| » Starters: Dutch Leonard vs Bill Steen | Eighth | 27½ out |
| Tuesday, July 28 |
| » Defeated Red Sox (51-41), 4-3 | League Park II (16-20) | 30-61 | |
| » Starters: Ray Collins vs Willie Mitchell | Eighth | 26½ out |
| Wednesday, July 29 |
| » Lost to Yankees (38-52), 6-2 | League Park II (16-21) | 30-62 | |
| » Starters: Ray Fisher vs Rip Hagerman | Eighth | 28 out |
| » Lost to Yankees (39-52), 10-6 | League Park II (16-22) | 30-63 | Lost 2 |
| » Starters: Boardwalk Brown vs Abe Bowman | Eighth | 28 out |
| Thursday, July 30 |
| » Lost to Yankees (40-52), 3-2 | League Park II (16-23) | 30-64 | Lost 3 |
| » Starters: King Cole vs Guy Morton | Eighth | 29½ out |
| » Lost to Yankees (41-52), 8-6 | League Park II (16-24) | 30-65 | Lost 4 |
| » Starters: Jack Warhop vs Fritz Coumbe | Eighth | 29½ out |
| Friday, July 31 |
| » Lost to Yankees (42-52), 7-2 | League Park II (16-25) | 30-66 | Lost 5 |
| » Starters: Ray Caldwell vs Fritz Coumbe | Eighth | 30½ out |
| Saturday, August 1 |
| » Defeated Yankees (42-53), 7-0 | League Park II (17-25) | 31-66 | |
| » Starters: Marty McHale vs Willie Mitchell | Eighth | 31 out |
| » Lost to Yankees (43-53), 9-2 | League Park II (17-26) | 31-67 | |
| » Starters: Ray Keating vs Allan Collamore | Eighth | 31 out |
| Sunday, August 2 |
| » Defeated Senators (52-42), 9-4 | League Park II (18-26) | 32-67 | |
| » Starters: Joe Boehling vs Bill Steen | Eighth | 31 out |
| Monday, August 3 |
| » Lost to Senators (53-42), 7-4 | League Park II (18-27) | 32-68 | |
| » Starters: Joe Engel vs Rip Hagerman | Eighth | 31 out |
| Tuesday, August 4 |
| » Lost to Senators (54-42), 7-6 | League Park II (18-28) | 32-69 | Lost 2 |
| » Starters: Joe Boehling vs Guy Morton | Eighth | 32 out |
| » Major-league debuts: Bill Wambsganss (Indians) |
| Wednesday, August 5 |
| » Defeated Senators (54-43), 3-2 | League Park II (19-28) | 33-69 | |
| » Starters: Walter Johnson vs Fred Blanding | Eighth | 32 out |
| Friday, August 7 |
| » Lost to Athletics (63-34), 4-0 | League Park II (19-29) | 33-70 | |
| » Starters: Chief Bender vs Willie Mitchell | Eighth | 33 out |
| Saturday, August 8 |
| » Lost to Athletics (64-34), 5-4 | League Park II (19-30) | 33-71 | Lost 2 |
| » Starters: Bob Shawkey vs Rip Hagerman | Eighth | 34 out |
| Sunday, August 9 |
| » Lost to Athletics (65-34), 10-5 | League Park II (19-31) | 33-72 | Lost 3 |
| » Starters: Eddie Plank vs Guy Morton | Eighth | 35 out |
| Monday, August 10 |
| » Lost to Athletics (66-34), 5-1 | League Park II (19-32) | 33-73 | Lost 4 |
| » Starters: Bullet Joe Bush vs Bill Steen | Eighth | 36 out |
| Tuesday, August 11 |
| » Lost to White Sox (52-53), 2-0 | Comiskey Park I (1-8) | 33-74 | Lost 5 |
| » Starters: Willie Mitchell vs Mellie Wolfgang | Eighth | 37 out |
| » Lost to White Sox (53-53), 2-0 | Comiskey Park I (1-9) | 33-75 | Lost 6 |
| » Starters: Guy Morton vs Eddie Cicotte | Eighth | 37 out |
| Wednesday, August 12 |
| » Defeated White Sox (53-54), 5-3 | Comiskey Park I (2-9) | 34-75 | |
| » Starters: Fred Blanding vs Joe Benz | Eighth | 36½ out |
| Thursday, August 13 |
| » Defeated Tigers (53-52), 6-3 | League Park II (20-32) | 35-75 | Won 2 |
| » Starters: Harry Coveleski vs Rip Hagerman | Eighth | 36½ out |
| Friday, August 14 |
| » Lost to Tigers (54-52), 8-4 | League Park II (20-33) | 35-76 | |
| » Starters: Hooks Dauss vs Bill Steen | Eighth | 36½ out |
| Saturday, August 15 |
| » Defeated Tigers (54-53), 7-1 | League Park II (21-33) | 36-76 | |
| » Starters: Jean Dubuc vs Willie Mitchell | Eighth | 36½ out |
| Sunday, August 16 |
| » Lost to Tigers (55-53), 13-6 | League Park II (21-34) | 36-77 | |
| » Starters: Ed McCreery vs Fred Blanding | Eighth | 37 out |
| Monday, August 17 |
| » Lost to Athletics (69-35), 5-0 | Shibe Park (1-7) | 36-78 | Lost 2 |
| » Starters: Fritz Coumbe vs Bullet Joe Bush | Eighth | 38 out |
| Tuesday, August 18 |
| » Defeated Yankees (49-61), 4-3 | Polo Grounds V (3-5) | 37-78 | |
| » Starters: Rip Hagerman vs King Cole | Eighth | 37½ out |
| Wednesday, August 19 |
| » Lost to Yankees (50-61), 7-5 | Polo Grounds V (3-6) | 37-79 | |
| » Starters: Bill Steen vs Boardwalk Brown | Eighth | 38½ out |
| Thursday, August 20 |
| » Defeated Yankees (50-62), 11-8 | Polo Grounds V (4-6) | 38-79 | |
| » Starters: Willie Mitchell vs Ray Fisher | Eighth | 38½ out |
| » Major-league debuts: Angel Aragon (Yankees) |
| Saturday, August 22 |
| » Lost to Red Sox (63-47), 4-2 | Fenway Park (3-6) | 38-80 | |
| » Starters: Guy Morton vs Rube Foster | Eighth | 39 out |
| Monday, August 24 |
| » Lost to Red Sox (64-47), 7-3 | Fenway Park (3-7) | 38-81 | Lost 2 |
| » Starters: Rip Hagerman vs Dutch Leonard | Eighth | 40½ out |
| Tuesday, August 25 |
| » Defeated Red Sox (64-48), 3-1 | Fenway Park (4-7) | 39-81 | |
| » Starters: Willie Mitchell vs Ernie Shore | Eighth | 41 out |
| Thursday, August 27 |
| » Lost to Senators (61-53), 1-0 | Griffith Stadium (3-6) | 39-82 | |
| » Starters: Bill Steen vs Jim Shaw | Eighth | 42½ out |
| » Tied Senators, 3-3 | Griffith Stadium (3-6) | 39-82 | |
| » Starters: Guy Morton vs Doc Ayers | Eighth | 42½ out |
| Saturday, August 29 |
| » Lost to Athletics (80-38), 2-1 | Shibe Park (1-8) | 39-83 | Lost 2 |
| » Starters: Willie Mitchell vs Bullet Joe Bush | Eighth | 43 out |
| Monday, August 31 |
| » Lost to Athletics (81-38), 9-3 | Shibe Park (1-9) | 39-84 | Lost 3 |
| » Starters: Fritz Coumbe vs Herb Pennock | Eighth | 44 out |
| Tuesday, September 1 |
| » Lost to Athletics (82-38), 16-3 | Shibe Park (1-10) | 39-85 | Lost 4 |
| » Starters: Bill Steen vs Chief Bender | Eighth | 45 out |
| Saturday, September 5 |
| » Defeated White Sox (60-64), 6-4 | League Park II (22-34) | 40-85 | |
| » Starters: Eddie Cicotte vs Willie Mitchell | Eighth | 43 out |
| » Lost to White Sox (61-64), 3-0 | League Park II (22-35) | 40-86 | |
| » Starters: Mellie Wolfgang vs Bill Steen | Eighth | 43 out |
| Sunday, September 6 |
| » Lost to White Sox (62-64), 6-1 | League Park II (22-36) | 40-87 | Lost 2 |
| » Starters: Jim Scott vs Guy Morton | Seventh | 43½ out |
| Monday, September 7 |
| » Defeated Browns (57-70), 4-3 | League Park II (23-36) | 41-87 | |
| » Starters: George Baumgardner vs Rip Hagerman | Eighth | 42½ out |
| » Defeated Browns (57-71), 6-2 | League Park II (24-36) | 42-87 | Won 2 |
| » Starters: Earl Hamilton vs Bill Steen | Eighth | 42½ out |
| Thursday, September 10 |
| » Lost to Browns (58-71), 6-5 | Sportsman's Park III (2-7) | 42-88 | |
| » Starters: Willie Mitchell vs Bill James | Eighth | 43 out |
| Saturday, September 12 |
| » Lost to Browns (59-71), 5-3 | Sportsman's Park III (2-8) | 42-89 | Lost 2 |
| » Starters: Rip Hagerman vs Carl Weilman | Eighth | 43 out |
| Sunday, September 13 |
| » Defeated Browns (59-72), 5-0 | Sportsman's Park III (3-8) | 43-89 | |
| » Starters: Willie Mitchell vs George Baumgardner | Eighth | 42½ out |
| » Tied Browns, 3-3 | Sportsman's Park III (3-8) | 43-89 | |
| » Starters: Fritz Coumbe vs Bill James | Eighth | 42½ out |
| Monday, September 14 |
| » Lost to Tigers (71-63), 6-4 | League Park II (24-37) | 43-90 | |
| » Starters: Harry Coveleski vs Lloyd Bishop | Eighth | 43½ out |
| Tuesday, September 15 |
| » Lost to Tigers (72-63), 2-1 | League Park II (24-38) | 43-91 | Lost 2 |
| » Starters: Pug Cavet vs Al Tedrow | Eighth | 44½ out |
| » Major-league debuts: Paul Carter (Indians) |
| Wednesday, September 16 |
| » Lost to Tigers (73-63), 8-3 | League Park II (24-39) | 43-92 | Lost 3 |
| » Starters: Red Oldham vs Paul Carter | Eighth | 45 out |
| Thursday, September 17 |
| » Lost to Red Sox (80-53), 8-1 | League Park II (24-40) | 43-93 | Lost 4 |
| » Starters: Rube Foster vs Willie Mitchell | Eighth | 46 out |
| » Major-league debuts: Walter Barbare (Indians) |
| Friday, September 18 |
| » Lost to Red Sox (81-53), 4-3 | League Park II (24-41) | 43-94 | Lost 5 |
| » Starters: Ernie Shore vs Bill Steen | Eighth | 46 out |
| Saturday, September 19 |
| » Defeated Red Sox (81-54), 5-1 | League Park II (25-41) | 44-94 | |
| » Starters: Ray Collins vs Al Tedrow | Eighth | 45 out |
| Sunday, September 20 |
| » Lost to Athletics (89-48), 4-1 | League Park II (25-42) | 44-95 | |
| » Starters: Chief Bender vs Guy Morton | Eighth | 46 out |
| » Major-league debuts: Elmer Smith (Indians) |
| Monday, September 21 |
| » Defeated Athletics (89-49), 5-4 | League Park II (26-42) | 45-95 | |
| » Starters: Bob Shawkey vs Abe Bowman | Eighth | 45 out |
| Tuesday, September 22 |
| » Lost to Athletics (90-49), 14-3 | League Park II (26-43) | 45-96 | |
| » Starters: Bullet Joe Bush vs Paul Carter | Eighth | 46 out |
| Thursday, September 24 |
| » Lost to Senators (74-66), 5-2 | League Park II (26-44) | 45-97 | Lost 2 |
| » Starters: Doc Ayers vs Willie Mitchell | Eighth | 47½ out |
| » Lost to Senators (75-66), 5-0 | League Park II (26-45) | 45-98 | Lost 3 |
| » Starters: Jim Shaw vs Abe Bowman | Eighth | 47½ out |
| Friday, September 25 |
| » Defeated Senators (75-67), 3-1 | League Park II (27-45) | 46-98 | |
| » Starters: Jack Bentley vs Bill Steen | Eighth | 47½ out |
| Saturday, September 26 |
| » Defeated Senators (75-68), 5-4 | League Park II (28-45) | 47-98 | Won 2 |
| » Starters: Joe Engel vs Rip Hagerman | Seventh | 48 out |
| » Lost to Senators (76-68), 6-0 | League Park II (28-46) | 47-99 | |
| » Starters: Jim Shaw vs Paul Carter | Seventh | 48 out |
| Sunday, September 27 |
| » Defeated Yankees (66-79), 5-3 | League Park II (29-46) | 48-99 | |
| » Starters: Marty McHale vs Guy Morton | Eighth | 48½ out |
| » Lost to Yankees (67-79), 5-2 | League Park II (29-47) | 48-100 | |
| » Starters: King Cole vs Al Tedrow | Eighth | 48½ out |
| Monday, September 28 |
| » Defeated Yankees (67-80), 5-2 | League Park II (30-47) | 49-100 | |
| » Starters: Boardwalk Brown vs Paul Carter | Eighth | 47½ out |
| Tuesday, September 29 |
| » Defeated White Sox (68-81), 10-4 | League Park II (31-47) | 50-100 | Won 2 |
| » Starters: Mellie Wolfgang vs Harley Dillinger | Eighth | 47 out |
| Wednesday, September 30 |
| » Defeated White Sox (68-82), 6-5 | League Park II (32-47) | 51-100 | Won 3 |
| » Starters: Joe Benz vs Fred Blanding | Eighth | 47 out |
| Thursday, October 1 |
| » Major-league debuts: Irish Meusel (Senators) |
| Saturday, October 3 |
| » Lost to Tigers (79-73), 6-5 | Tiger Stadium (2-8) | 51-101 | |
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