| Saturday, March 22 |
| Future White Sox Hank Steinbacher is born in Sacramento, CA. |
| Wednesday, April 9 |
| » Major-league debuts: Benny Meyer (Dodgers) |
| Thursday, April 10 |
| » Major-league debuts: Ralph Young (Yankees) |
| Friday, April 11 |
| » Lost to Indians (1-0), 3-1 | League Park II (0-1) | 0-1 | |
| » Starters: Jim Scott vs Vean Gregg | Third | 1½ out |
| Saturday, April 12 |
| » Defeated Indians (1-1), 13-3 | League Park II (1-1) | 1-1 | |
| » Starters: Joe Benz vs Willie Mitchell | Third | 1 out |
| » Major-league debuts: Nemo Leibold (Indians) |
| Sunday, April 13 |
| » Defeated Browns (2-1), 7-2 | Sportsman's Park III (1-0) | 2-1 | Won 2 |
| » Starters: Frank Lange vs Walt Leverenz | Third | ½ out |
| » Major-league debuts: Dwight Stone and Ernie Walker (Browns) |
| Monday, April 14 |
| » Lost to Browns (3-1), 2-1 | Sportsman's Park III (1-1) | 2-2 | |
| » Starters: Doc White vs Carl Weilman | Fourth | 1 out |
| Tuesday, April 15 |
| » Defeated Browns (3-2), 5-3 | Sportsman's Park III (2-1) | 3-2 | |
| » Starters: Ed Walsh vs Roy Mitchell | Third | 1½ out |
| Wednesday, April 16 |
| » Defeated Browns (3-3), 3-2 | Sportsman's Park III (3-1) | 4-2 | Won 2 |
| » Starters: Eddie Cicotte vs George Baumgardner | Third | 2 out |
| Thursday, April 17 |
| » Defeated Indians (3-3), 2-1 | Comiskey Park I (1-0) | 5-2 | Won 3 |
| » Starters: Willie Mitchell vs Jim Scott | Third | 2 out |
| Friday, April 18 |
| » Lost to Indians (4-3), 4-0 | Comiskey Park I (1-1) | 5-3 | |
| » Starters: Bill Steen vs Joe Benz | Third | 2½ out |
| » Major-league debuts: Reb Russell (White Sox) |
| Saturday, April 19 |
| » Lost to Indians (5-3), 9-2 | Comiskey Park I (1-2) | 5-4 | Lost 2 |
| » Starters: Cy Falkenberg vs Frank Lange | Fourth | 2½ out |
| Sunday, April 20 |
| » Lost to Indians (6-3), 2-1 | Comiskey Park I (1-3) | 5-5 | Lost 3 |
| » Starters: Vean Gregg vs Ed Walsh | Fourth | 3 out |
| Monday, April 21 |
| » Lost to Tigers (5-5), 3-2 | Comiskey Park I (1-4) | 5-6 | Lost 4 |
| » Starters: Al Klawitter vs Reb Russell | Fifth | 3 out |
| Tuesday, April 22 |
| » Defeated Tigers (5-6), 3-2 | Comiskey Park I (2-4) | 6-6 | |
| » Starters: Fred House vs Jim Scott | Fourth | 2½ out |
| » Major-league debuts: Frank Gibson (Tigers) |
| Wednesday, April 23 |
| » Defeated Tigers (5-7), 2-1 | Comiskey Park I (3-4) | 7-6 | Won 2 |
| » Starters: Marc Hall vs Doc White | Fourth | 3 out |
| Thursday, April 24 |
| » Lost to Browns (6-8), 3-1 | Comiskey Park I (3-5) | 7-7 | |
| » Starters: Roy Mitchell vs Eddie Cicotte | Fourth | 2½ out |
| Saturday, April 26 |
| » Defeated Browns (6-9), 1-0 | Comiskey Park I (4-5) | 8-7 | |
| » Starters: Dwight Stone vs Reb Russell | Fourth | 3 out |
| Sunday, April 27 |
| » Lost to Browns (7-9), 3-0 | Comiskey Park I (4-6) | 8-8 | |
| » Starters: Earl Hamilton vs Jim Scott | Fourth | 3½ out |
| Tuesday, April 29 |
| » Defeated Tigers (5-10), 6-5 | Tiger Stadium (1-0) | 9-8 | |
| » Starters: Doc White vs Marc Hall | Fourth | 3 out |
| Wednesday, April 30 |
| » Defeated Tigers (5-11), 8-3 | Tiger Stadium (2-0) | 10-8 | Won 2 |
| » Starters: Eddie Cicotte vs Jean Dubuc | Fourth | 3 out |
| Thursday, May 1 |
| » Defeated Tigers (5-12), 8-5 | Tiger Stadium (3-0) | 11-8 | Won 3 |
| » Starters: Reb Russell vs George Mullin | Fourth | 3 out |
| Friday, May 2 |
| » Defeated Tigers (5-13), 2-1 | Tiger Stadium (4-0) | 12-8 | Won 4 |
| » Starters: Jim Scott vs Ed Willett | Fourth | 3 out |
| Saturday, May 3 |
| » Defeated Tigers (5-14), 6-4 | Tiger Stadium (5-0) | 13-8 | Won 5 |
| » Starters: Joe Benz vs Marc Hall | Fourth | 3 out |
| Sunday, May 4 |
| » Lost to Tigers (6-14), 2-1 | Comiskey Park I (4-7) | 13-9 | |
| » Starters: Jean Dubuc vs Doc White | Fourth | 3½ out |
| Wednesday, May 7 |
| » Lost to Senators (12-4), 3-2 | Comiskey Park I (4-8) | 13-10 | Lost 2 |
| » Starters: Tom Hughes vs Eddie Cicotte | Fourth | 4 out |
| Thursday, May 8 |
| » Defeated Senators (12-5), 10-5 | Comiskey Park I (5-8) | 14-10 | |
| » Starters: Bob Groom vs Reb Russell | Fourth | 4 out |
| Friday, May 9 |
| » Defeated Senators (12-6), 6-1 | Comiskey Park I (6-8) | 15-10 | Won 2 |
| » Starters: Joe Engel vs Jim Scott | Fourth | 3 out |
| Saturday, May 10 |
| » Lost to Senators (13-6), 1-0 | Comiskey Park I (6-9) | 15-11 | |
| » Starters: Walter Johnson vs Joe Benz | Fourth | 4 out |
| Sunday, May 11 |
| » Defeated Athletics (16-5), 4-3 | Comiskey Park I (7-9) | 16-11 | |
| » Starters: Boardwalk Brown vs Ed Walsh | Fourth | 3 out |
| Monday, May 12 |
| » Lost to Athletics (17-5), 3-0 | Comiskey Park I (7-10) | 16-12 | |
| » Starters: Chief Bender vs Reb Russell | Fourth | 4 out |
| Thursday, May 15 |
| » Defeated Yankees (7-18), 3-2 | Comiskey Park I (8-10) | 17-12 | |
| » Starters: Al Schulz vs Jim Scott | Fourth | 3 out |
| Friday, May 16 |
| » Defeated Yankees (7-19), 7-0 | Comiskey Park I (9-10) | 18-12 | Won 2 |
| » Starters: George McConnell vs Joe Benz | Fourth | 3 out |
| Saturday, May 17 |
| » Defeated Yankees (7-20), 6-3 | Comiskey Park I (10-10) | 19-12 | Won 3 |
| » Starters: Ray Keating vs Reb Russell | Fourth | 3 out |
| Sunday, May 18 |
| » Defeated Yankees (7-21), 5-3 | Comiskey Park I (11-10) | 20-12 | Won 4 |
| » Starters: Ray Fisher vs Ed Walsh | Fourth | 3 out |
| Monday, May 19 |
| » Lost to Red Sox (13-18), 10-1 | Comiskey Park I (11-11) | 20-13 | |
| » Starters: Joe Wood vs Jim Scott | Fourth | 3 out |
| Tuesday, May 20 |
| » Major-league debuts: Nick Cullop (Indians) |
| Wednesday, May 21 |
| » Lost to Red Sox (14-18), 10-9 | Comiskey Park I (11-12) | 20-14 | Lost 2 |
| » Starters: Ray Collins vs Joe Benz | Fourth | 3 out |
| Thursday, May 22 |
| » Defeated Red Sox (14-19), 2-1 | Comiskey Park I (12-12) | 21-14 | |
| » Starters: Buck O'Brien vs Reb Russell | Third | 3 out |
| Saturday, May 24 |
| » Lost to Indians (23-12), 4-3 | Comiskey Park I (12-13) | 21-15 | |
| » Starters: Cy Falkenberg vs Ed Walsh | Third | 3 out |
| Sunday, May 25 |
| » Lost to Indians (24-12), 8-1 | Comiskey Park I (12-14) | 21-16 | Lost 2 |
| » Starters: Willie Mitchell vs Reb Russell | Fourth | 3½ out |
| Wednesday, May 28 |
| » Lost to Indians (25-12), 2-1 | League Park II (1-2) | 21-17 | Lost 3 |
| » Starters: Eddie Cicotte vs George Kahler | Fourth | 5½ out |
| » Lost to Indians (26-12), 5-3 | League Park II (1-3) | 21-18 | Lost 4 |
| » Starters: Ed Walsh vs Vean Gregg | Fourth | 5½ out |
| Thursday, May 29 |
| » Defeated Tigers (16-25), 3-2 | Comiskey Park I (13-14) | 22-18 | |
| » Starters: Ed Willett vs Reb Russell | Fourth | 5½ out |
| Friday, May 30 |
| » Lost to Tigers (17-25), 3-2 | Comiskey Park I (13-15) | 22-19 | |
| » Starters: Joe Lake vs Pop-boy Smith | Fourth | 6½ out |
| » Defeated Tigers (17-26), 9-1 | Comiskey Park I (14-15) | 23-19 | |
| » Starters: Hooks Dauss vs Eddie Cicotte | Fourth | 6½ out |
| Saturday, May 31 |
| » Defeated Tigers (17-27), 3-2 | Comiskey Park I (15-15) | 24-19 | Won 2 |
| » Starters: Carl Zamloch vs Doc White | Fourth | 6½ out |
| Sunday, June 1 |
| » Lost to Tigers (18-27), 1-0 | Comiskey Park I (15-16) | 24-20 | |
| » Starters: Marc Hall vs Jim Scott | Fourth | 7 out |
| Tuesday, June 3 |
| » Lost to Red Sox (19-22), 3-2 | Fenway Park (0-1) | 24-21 | Lost 2 |
| » Starters: Reb Russell vs Ray Collins | Fourth | 9 out |
| Wednesday, June 4 |
| » Defeated Red Sox (19-23), 4-1 | Fenway Park (1-1) | 25-21 | |
| » Starters: Eddie Cicotte vs Buck O'Brien | Fourth | 9 out |
| Thursday, June 5 |
| » Defeated Red Sox (19-24), 5-0 | Fenway Park (2-1) | 26-21 | Won 2 |
| » Starters: Jim Scott vs Dutch Leonard | Third | 9 out |
| Friday, June 6 |
| » Lost to Red Sox (20-24), 4-3 | Fenway Park (2-2) | 26-22 | |
| » Starters: Doc White vs Joe Wood | Fourth | 10 out |
| Saturday, June 7 |
| » Lost to Yankees (10-34), 3-2 | Polo Grounds V (0-1) | 26-23 | Lost 2 |
| » Starters: Ed Walsh vs Ray Keating | Fourth | 11 out |
| Monday, June 9 |
| » Lost to Yankees (11-34), 4-1 | Polo Grounds V (0-2) | 26-24 | Lost 3 |
| » Starters: Eddie Cicotte vs Russ Ford | Fourth | 12 out |
| Tuesday, June 10 |
| » Defeated Yankees (11-35), 5-1 | Polo Grounds V (1-2) | 27-24 | |
| » Starters: Jim Scott vs George McConnell | Fourth | 12 out |
| Wednesday, June 11 |
| » Defeated Yankees (11-36), 1-0 | Polo Grounds V (2-2) | 28-24 | Won 2 |
| » Starters: Reb Russell vs Ray Fisher | Third | 11 out |
| Thursday, June 12 |
| » Lost to Senators (27-23), 5-4 | Griffith Stadium (0-1) | 28-25 | |
| » Starters: Eddie Cicotte vs Bob Groom | Fourth | 12 out |
| Friday, June 13 |
| » Defeated Senators (27-24), 6-4 | Griffith Stadium (1-1) | 29-25 | |
| » Starters: Ed Walsh vs Tom Hughes | Third | 12 out |
| Saturday, June 14 |
| » Lost to Senators (28-24), 8-3 | Griffith Stadium (1-2) | 29-26 | |
| » Starters: Jim Scott vs Walter Johnson | Fourth | 12 out |
| Sunday, June 15 |
| » Major-league debuts: Dave Gregg (Indians) Merito Acosta (Senators) |
| Monday, June 16 |
| » Defeated Senators (29-25), 4-1 | Griffith Stadium (2-2) | 30-26 | |
| » Starters: Reb Russell vs Bob Groom | Fourth | 12 out |
| Tuesday, June 17 |
| » Lost to Athletics (41-12), 7-1 | Shibe Park (0-1) | 30-27 | |
| » Starters: Jim Scott vs Byron Houck | Fourth | 13 out |
| Wednesday, June 18 |
| » Defeated Athletics (41-13), 9-5 | Shibe Park (1-1) | 31-27 | |
| » Starters: Ed Walsh vs Chief Bender | Fourth | 12 out |
| Thursday, June 19 |
| » Lost to Athletics (42-13), 2-0 | Shibe Park (1-2) | 31-28 | |
| » Starters: Reb Russell vs Boardwalk Brown | Fifth | 13 out |
| Friday, June 20 |
| » Defeated Indians (37-22), 3-0 | League Park II (2-3) | 32-28 | |
| » Starters: Eddie Cicotte vs George Kahler | Fourth | 12 out |
| Sunday, June 22 |
| » Lost to Browns (23-41), 2-0 | Comiskey Park I (15-17) | 32-29 | |
| » Starters: Walt Leverenz vs Jim Scott | Fifth | 11½ out |
| » Defeated Browns (23-42), 2-0 | Comiskey Park I (16-17) | 33-29 | |
| » Starters: Carl Weilman vs Ed Walsh | Fifth | 11½ out |
| » Major-league debuts: Doc Lavan (Browns) |
| Monday, June 23 |
| » Lost to Browns (24-42), 3-1 | Comiskey Park I (16-18) | 33-30 | |
| » Starters: George Baumgardner vs Eddie Cicotte | Fifth | 12 out |
| » Defeated Browns (24-43), 4-3 | Comiskey Park I (17-18) | 34-30 | |
| » Starters: Earl Hamilton vs Reb Russell | Fifth | 12 out |
| Tuesday, June 24 |
| » Lost to Browns (25-43), 8-0 | Comiskey Park I (17-19) | 34-31 | |
| » Starters: Roy Mitchell vs Frank Lange | Fifth | 12½ out |
| Wednesday, June 25 |
| » Defeated Browns (25-44), 4-1 | Comiskey Park I (18-19) | 35-31 | |
| » Starters: Mack Allison vs Jim Scott | Fourth | 12½ out |
| Thursday, June 26 |
| » Defeated Indians (40-26), 7-5 | Comiskey Park I (19-19) | 36-31 | Won 2 |
| » Starters: Vean Gregg vs Ed Walsh | Third | 13 out |
| Friday, June 27 |
| » Defeated Indians (40-27), 3-2 | Comiskey Park I (20-19) | 37-31 | Won 3 |
| » Starters: Cy Falkenberg vs Eddie Cicotte | Third | 12½ out |
| Saturday, June 28 |
| » Lost to Indians (41-27), 3-2 | Comiskey Park I (20-20) | 37-32 | |
| » Starters: Willie Mitchell vs Jim Scott | Fourth | 12½ out |
| Sunday, June 29 |
| » Defeated Indians (41-28), 2-1 | Comiskey Park I (21-20) | 38-32 | |
| » Starters: George Kahler vs Reb Russell | Third | 12 out |
| Monday, June 30 |
| » Defeated Tigers (28-44), 6-4 | Tiger Stadium (6-0) | 39-32 | Won 2 |
| » Starters: Doc White vs Marc Hall | Third | 12 out |
| Tuesday, July 1 |
| » Defeated Tigers (28-45), 3-2 | Tiger Stadium (7-0) | 40-32 | Won 3 |
| » Starters: Eddie Cicotte vs Ed Willett | Third | 12 out |
| Wednesday, July 2 |
| » Lost to Tigers (29-45), 7-5 | Tiger Stadium (7-1) | 40-33 | |
| » Starters: Joe Benz vs Joe Lake | Fourth | 13 out |
| Thursday, July 3 |
| » Defeated Browns (29-48), 4-3 | Sportsman's Park III (4-1) | 41-33 | |
| » Starters: Jim Scott vs Roy Mitchell | Fourth | 13 out |
| Friday, July 4 |
| » Lost to Browns (30-48), 6-1 | Sportsman's Park III (4-2) | 41-34 | |
| » Starters: Joe Benz vs Walt Leverenz | Fourth | 13 out |
| » Defeated Browns (30-49), 2-1 | Sportsman's Park III (5-2) | 42-34 | |
| » Starters: Reb Russell vs George Baumgardner | Fourth | 13 out |
| Saturday, July 5 |
| » Tied Indians, 5-5 | League Park II (2-3) | 42-34 | |
| » Starters: Jim Scott vs Nick Cullop | Fourth | 13½ out |
| Sunday, July 6 |
| » Lost to Indians (47-29), 6-2 | League Park II (2-4) | 42-35 | |
| » Starters: Eddie Cicotte vs Cy Falkenberg | Fourth | 14½ out |
| » Lost to Indians (48-29), 7-0 | League Park II (2-5) | 42-36 | Lost 2 |
| » Starters: Reb Russell vs Willie Mitchell | Fourth | 14½ out |
| Wednesday, July 9 |
| » Defeated Yankees (21-52), 2-0 | Comiskey Park I (22-20) | 43-36 | |
| » Starters: Russ Ford vs Jim Scott | Fourth | 14½ out |
| Thursday, July 10 |
| » Lost to Yankees (22-52), 2-1 | Comiskey Park I (22-21) | 43-37 | |
| » Starters: Jack Warhop vs Reb Russell | Fourth | 14½ out |
| Friday, July 11 |
| » Lost to Yankees (23-52), 11-1 | Comiskey Park I (22-22) | 43-38 | Lost 2 |
| » Starters: Ray Keating vs Buck O'Brien | Fourth | 15½ out |
| Saturday, July 12 |
| » Defeated Red Sox (38-38), 7-2 | Comiskey Park I (23-22) | 44-38 | |
| » Starters: Charley Hall vs Eddie Cicotte | Fourth | 16 out |
| » Lost to Red Sox (39-38), 9-0 | Comiskey Park I (23-23) | 44-39 | |
| » Starters: Joe Wood vs Frank Miller | Fourth | 16 out |
| » Major-league debuts: Frank Miller (White Sox) |
| Sunday, July 13 |
| » Defeated Red Sox (39-39), 3-2 | Comiskey Park I (24-23) | 45-39 | |
| » Starters: Ray Collins vs Jim Scott | Fourth | 14½ out |
| Monday, July 14 |
| » Defeated Red Sox (39-40), 8-0 | Comiskey Park I (25-23) | 46-39 | Won 2 |
| » Starters: Rube Foster vs Reb Russell | Fourth | 13½ out |
| Tuesday, July 15 |
| » Defeated Red Sox (39-41), 2-1 | Comiskey Park I (26-23) | 47-39 | Won 3 |
| » Starters: Dutch Leonard vs Ed Walsh | Fourth | 13½ out |
| Wednesday, July 16 |
| » Lost to Athletics (59-23), 1-0 | Comiskey Park I (26-24) | 47-40 | |
| » Starters: Boardwalk Brown vs Eddie Cicotte | Fourth | 13½ out |
| » Defeated Athletics (59-24), 5-3 | Comiskey Park I (27-24) | 48-40 | |
| » Starters: Bob Shawkey vs Buck O'Brien | Fourth | 13½ out |
| Thursday, July 17 |
| » Defeated Athletics (59-25), 5-2 | Comiskey Park I (28-24) | 49-40 | Won 2 |
| » Starters: Bullet Joe Bush vs Jim Scott | Fourth | 12½ out |
| Friday, July 18 |
| » Lost to Athletics (60-25), 4-1 | Comiskey Park I (28-25) | 49-41 | |
| » Starters: Chief Bender vs Reb Russell | Fourth | 13½ out |
| » Major-league debuts: Larry Chappell (White Sox) |
| Saturday, July 19 |
| » Defeated Athletics (60-26), 4-3 | Comiskey Park I (29-25) | 50-41 | |
| » Starters: Boardwalk Brown vs Eddie Cicotte | Fourth | 13½ out |
| » Lost to Athletics (61-26), 3-1 | Comiskey Park I (29-26) | 50-42 | |
| » Starters: Boardwalk Brown vs Ed Walsh | Fourth | 13½ out |
| Former White Sox Jiggs Donahue dies in Columbus, OH at the age of 35. |
| Sunday, July 20 |
| » Lost to Senators (50-38), 5-1 | Comiskey Park I (29-27) | 50-43 | Lost 2 |
| » Starters: Joe Boehling vs Doc White | Fourth | 14½ out |
| Monday, July 21 |
| » Lost to Senators (51-38), 2-1 | Comiskey Park I (29-28) | 50-44 | Lost 3 |
| » Starters: Walter Johnson vs Reb Russell | Fourth | 15½ out |
| Tuesday, July 22 |
| » Defeated Senators (51-39), 6-5 | Comiskey Park I (30-28) | 51-44 | |
| » Starters: Bob Groom vs Reb Russell | Fourth | 14½ out |
| Wednesday, July 23 |
| » Lost to Senators (52-39), 7-1 | Comiskey Park I (30-29) | 51-45 | |
| » Starters: Joe Boehling vs Jim Scott | Fourth | 15½ out |
| Friday, July 25 |
| » Lost to Red Sox (43-46), 7-5 | Fenway Park (2-3) | 51-46 | Lost 2 |
| » Starters: Eddie Cicotte vs Hugh Bedient | Fourth | 16½ out |
| Saturday, July 26 |
| » Lost to Red Sox (44-46), 4-1 | Fenway Park (2-4) | 51-47 | Lost 3 |
| » Starters: Reb Russell vs Ray Collins | Fourth | 16½ out |
| Tuesday, July 29 |
| » Lost to Red Sox (45-46), 2-0 | Fenway Park (2-5) | 51-48 | Lost 4 |
| » Starters: Jim Scott vs Rube Foster | Fourth | 18 out |
| » Lost to Red Sox (46-46), 5-3 | Fenway Park (2-6) | 51-49 | Lost 5 |
| » Starters: Buck O'Brien vs Dutch Leonard | Fourth | 18 out |
| Wednesday, July 30 |
| » Lost to Yankees (30-62), 3-0 | Polo Grounds V (2-3) | 51-50 | Lost 6 |
| » Starters: Reb Russell vs Ray Fisher | Fourth | 19 out |
| Thursday, July 31 |
| » Lost to Yankees (31-62), 3-1 | Polo Grounds V (2-4) | 51-51 | Lost 7 |
| » Starters: Eddie Cicotte vs Ray Caldwell | Fourth | 19 out |
| Saturday, August 2 |
| » Defeated Yankees (31-63), 4-1 | Polo Grounds V (3-4) | 52-51 | |
| » Starters: Jim Scott vs Jack Warhop | Fourth | 18½ out |
| Monday, August 4 |
| » Defeated Senators (56-43), 5-3 | Griffith Stadium (3-2) | 53-51 | Won 2 |
| » Starters: Reb Russell vs Joe Engel | Fourth | 18½ out |
| Tuesday, August 5 |
| » Defeated Senators (56-44), 4-2 | Griffith Stadium (4-2) | 54-51 | Won 3 |
| » Starters: Joe Benz vs Joe Boehling | Fourth | 17½ out |
| Wednesday, August 6 |
| » Lost to Senators (57-44), 11-2 | Griffith Stadium (4-3) | 54-52 | |
| » Starters: Pop-boy Smith vs Walter Johnson | Fourth | 18½ out |
| Thursday, August 7 |
| » Defeated Senators (57-45), 11-4 | Griffith Stadium (5-3) | 55-52 | |
| » Starters: Eddie Cicotte vs Joe Engel | Fourth | 18½ out |
| Friday, August 8 |
| » Defeated Athletics (71-32), 4-1 | Shibe Park (2-2) | 56-52 | Won 2 |
| » Starters: Jim Scott vs Boardwalk Brown | Fourth | 17½ out |
| Saturday, August 9 |
| » Defeated Athletics (71-33), 1-0 | Shibe Park (3-2) | 57-52 | Won 3 |
| » Starters: Reb Russell vs Bob Shawkey | Fourth | 16½ out |
| Monday, August 11 |
| » Lost to Athletics (72-33), 8-5 | Shibe Park (3-3) | 57-53 | |
| » Starters: Eddie Cicotte vs Bullet Joe Bush | Fourth | 17½ out |
| Tuesday, August 12 |
| » Defeated Athletics (72-34), 4-2 | Shibe Park (4-3) | 58-53 | |
| » Starters: Jim Scott vs Boardwalk Brown | Fourth | 16½ out |
| Thursday, August 14 |
| » Lost to Yankees (36-67), 2-0 | Comiskey Park I (30-30) | 58-54 | |
| » Starters: Russ Ford vs Reb Russell | Fourth | 16½ out |
| Friday, August 15 |
| » Defeated Yankees (36-68), 3-2 | Comiskey Park I (31-30) | 59-54 | |
| » Starters: Ray Caldwell vs Eddie Cicotte | Fourth | 16½ out |
| Saturday, August 16 |
| » Defeated Yankees (36-69), 2-0 | Comiskey Park I (32-30) | 60-54 | Won 2 |
| » Starters: Ray Fisher vs Jim Scott | Fourth | 15½ out |
| Sunday, August 17 |
| » Lost to Yankees (37-69), 3-2 | Comiskey Park I (32-31) | 60-55 | |
| » Starters: Ray Keating vs Joe Benz | Fourth | 15½ out |
| Monday, August 18 |
| » Defeated Red Sox (53-56), 1-0 | Comiskey Park I (33-31) | 61-55 | |
| » Starters: Hugh Bedient vs Reb Russell | Fourth | 14½ out |
| Tuesday, August 19 |
| » Defeated Red Sox (53-57), 5-1 | Comiskey Park I (34-31) | 62-55 | Won 2 |
| » Starters: Ray Collins vs Eddie Cicotte | Fourth | 14½ out |
| Wednesday, August 20 |
| » Defeated Red Sox (53-58), 1-0 | Comiskey Park I (35-31) | 63-55 | Won 3 |
| » Starters: Fred Anderson vs Jim Scott | Fourth | 14½ out |
| » Major-league debuts: Edd Roush (White Sox) |
| Thursday, August 21 |
| » Lost to Athletics (76-38), 7-1 | Comiskey Park I (35-32) | 63-56 | |
| » Starters: Bob Shawkey vs Joe Benz | Fourth | 15½ out |
| Friday, August 22 |
| » Lost to Athletics (77-38), 2-1 | Comiskey Park I (35-33) | 63-57 | Lost 2 |
| » Starters: Byron Houck vs Reb Russell | Fourth | 16½ out |
| Saturday, August 23 |
| » Defeated Athletics (77-39), 7-4 | Comiskey Park I (36-33) | 64-57 | |
| » Starters: Boardwalk Brown vs Eddie Cicotte | Fourth | 15½ out |
| Sunday, August 24 |
| » Lost to Senators (66-50), 2-1 | Comiskey Park I (36-34) | 64-58 | |
| » Starters: Walter Johnson vs Jim Scott | Fourth | 16½ out |
| Monday, August 25 |
| » Defeated Senators (66-51), 5-2 | Comiskey Park I (37-34) | 65-58 | |
| » Starters: Bob Groom vs Reb Russell | Fourth | 16½ out |
| Tuesday, August 26 |
| » Lost to Senators (67-51), 5-3 | Comiskey Park I (37-35) | 65-59 | |
| » Starters: Joe Boehling vs Jim Scoggins | Fourth | 17½ out |
| Wednesday, August 27 |
| » Major-league debuts: Rube Schauer (Giants) |
| Saturday, August 30 |
| » Lost to Tigers (53-71), 8-5 | Comiskey Park I (37-36) | 65-60 | Lost 2 |
| » Starters: Jean Dubuc vs Jim Scott | Fourth | 17½ out |
| Sunday, August 31 |
| » Lost to Tigers (54-71), 5-4 | Comiskey Park I (37-37) | 65-61 | Lost 3 |
| » Starters: Ed Willett vs Reb Russell | Fourth | 18 out |
| Monday, September 1 |
| » Lost to Indians (76-49), 6-2 | League Park II (2-6) | 65-62 | Lost 4 |
| » Starters: Eddie Cicotte vs Lefty James | Fourth | 20 out |
| » Lost to Indians (77-49), 7-0 | League Park II (2-7) | 65-63 | Lost 5 |
| » Starters: Jim Scott vs Cy Falkenberg | Fourth | 20 out |
| Tuesday, September 2 |
| » Defeated Indians (77-50), 3-1 | League Park II (3-7) | 66-63 | |
| » Starters: Jim Scott vs Bill Steen | Fourth | 18½ out |
| » Defeated Indians (77-51), 9-3 | League Park II (4-7) | 67-63 | Won 2 |
| » Starters: Joe Benz vs Fred Blanding | Fourth | 18½ out |
| » Major-league debuts: Larry Kopf (Indians) |
| Wednesday, September 3 |
| Future White Sox Kerby Farrell is born in Leapwood, TN. |
| Thursday, September 4 |
| » Lost to Browns (49-83), 5-4 | Sportsman's Park III (5-3) | 67-64 | |
| » Starters: Reb Russell vs Hal Schwenk | Fourth | 18½ out |
| » Major-league debuts: Hal Schwenk (Browns) |
| Friday, September 5 |
| » Defeated Browns (49-84), 1-0 | Sportsman's Park III (6-3) | 68-64 | |
| » Starters: Eddie Cicotte vs Wiley Taylor | Fourth | 17½ out |
| Saturday, September 6 |
| » Lost to Browns (50-84), 4-0 | Sportsman's Park III (6-4) | 68-65 | |
| » Starters: Jim Scott vs Roy Mitchell | Fourth | 18½ out |
| » Major-league debuts: Bill Meyer (White Sox) |
| Sunday, September 7 |
| » Lost to Browns (51-84), 1-0 | Sportsman's Park III (6-5) | 68-66 | Lost 2 |
| » Starters: Joe Benz vs George Baumgardner | Fifth | 19 out |
| Monday, September 8 |
| » Major-league debuts: Slim Love and Ben Spencer (Senators) |
| Tuesday, September 9 |
| » Defeated Athletics (85-46), 2-0 | Shibe Park (5-3) | 69-66 | |
| » Starters: Reb Russell vs Chief Bender | Fifth | 18 out |
| Wednesday, September 10 |
| » Defeated Athletics (85-47), 5-3 | Shibe Park (6-3) | 70-66 | Won 2 |
| » Starters: Eddie Cicotte vs Boardwalk Brown | Fourth | 17 out |
| Thursday, September 11 |
| » Lost to Athletics (86-47), 4-1 | Shibe Park (6-4) | 70-67 | |
| » Starters: Jim Scott vs Bob Shawkey | Fourth | 18 out |
| Friday, September 12 |
| » Lost to Athletics (87-47), 7-5 | Shibe Park (6-5) | 70-68 | Lost 2 |
| » Starters: Joe Benz vs Eddie Plank | Fifth | 19 out |
| Saturday, September 13 |
| » Defeated Senators (78-58), 6-4 | Griffith Stadium (6-3) | 71-68 | |
| » Starters: Eddie Cicotte vs Joe Boehling | Fifth | 18 out |
| Monday, September 15 |
| » Defeated Senators (78-59), 5-0 | Griffith Stadium (7-3) | 72-68 | Won 2 |
| » Starters: Reb Russell vs Bob Groom | Fifth | 18 out |
| » Major-league debuts: Jim Shaw (Senators) |
| Tuesday, September 16 |
| » Lost to Senators (79-59), 2-1 | Griffith Stadium (7-4) | 72-69 | |
| » Starters: Joe Benz vs Walter Johnson | Fifth | 19 out |
| Wednesday, September 17 |
| » Defeated Yankees (49-87), 9-3 | Polo Grounds V (4-4) | 73-69 | |
| » Starters: Jim Scott vs Russ Ford | Fifth | 19½ out |
| » Lost to Yankees (50-87), 3-2 | Polo Grounds V (4-5) | 73-70 | |
| » Starters: Eddie Cicotte vs Ray Fisher | Fifth | 19½ out |
| Thursday, September 18 |
| » Lost to Yankees (51-87), 6-3 | Polo Grounds V (4-6) | 73-71 | Lost 2 |
| » Starters: Reb Russell vs Marty McHale | Fifth | 19½ out |
| Tuesday, September 23 |
| » Lost to Red Sox (73-65), 3-2 | Fenway Park (2-7) | 73-72 | Lost 3 |
| » Starters: Jim Scott vs Ray Collins | Fifth | 21½ out |
| » Defeated Red Sox (73-66), 3-2 | Fenway Park (3-7) | 74-72 | |
| » Starters: Ed Walsh vs Hugh Bedient | Fifth | 21½ out |
| » Major-league debuts: Tom Daly (White Sox) |
| Friday, September 26 |
| » Defeated Browns (55-93), 3-2 | Comiskey Park I (38-37) | 75-72 | Won 2 |
| » Starters: Walt Leverenz vs Joe Benz | Fifth | 20½ out |
| Saturday, September 27 |
| » Defeated Browns (55-94), 6-2 | Comiskey Park I (39-37) | 76-72 | Won 3 |
| » Starters: George Baumgardner vs Jim Scott | Fifth | 19½ out |
| Sunday, September 28 |
| » Defeated Indians (83-65), 1-0 | Comiskey Park I (40-37) | 77-72 | Won 4 |
| » Starters: Cy Falkenberg vs Eddie Cicotte | Fifth | 19 out |
| Saturday, October 4 |
| » Lost to Tigers (65-86), 7-5 | Tiger Stadium (7-2) | 77-73 | |
| » Starters: Joe Benz vs Hooks Dauss | Fifth | 17 out |
| » Defeated Tigers (65-87), 1-0 | Tiger Stadium (8-2) | 78-73 | |
| » Starters: Reb Russell vs Lefty Williams | Fifth | 17 out |
| Sunday, October 5 |
| » Lost to Tigers (66-87), 9-8 | Tiger Stadium (8-3) | 78-74 | |
| » Starters: Jim Scott vs Ralph Comstock | Fifth | 17½ out |
| Monday, October 13 |
| Former White Sox Mike Heydon dies in Indianapolis, IN at the age of 40. |
| Sunday, December 14 |
| Future White Sox Eddie Smith is born in Mansfield, NJ. |
Game information provided by Retrosheet (www.retrosheet.org) |
