| Monday, January 20 |
| Future Tiger Jimmy Outlaw is born in Orme, TN. |
| Thursday, February 13 |
| Future Tiger Hack Miller is born in Celeste, TX. |
| Wednesday, April 9 |
| » Major-league debuts: Benny Meyer (Dodgers) |
| Thursday, April 10 |
| » Lost to Browns (1-0), 3-1 | Sportsman's Park III (0-1) | 0-1 | |
| » Starters: George Mullin vs Carl Weilman | Third | 1 out |
| » Major-league debuts: Sam Agnew and Dee Walsh (Browns) |
| Friday, April 11 |
| » Lost to Browns (2-0), 8-6 | Sportsman's Park III (0-2) | 0-2 | Lost 2 |
| » Starters: Al Klawitter vs Earl Hamilton | Fourth | 2 out |
| » Major-league debuts: Hugh High (Tigers) |
| Saturday, April 12 |
| » Major-league debuts: Hub Leonard (Red Sox) |
| Sunday, April 13 |
| » Major-league debuts: Dwight Stone and Ernie Walker (Browns) |
| Monday, April 14 |
| » Defeated Indians (1-2), 5-4 | League Park II (1-0) | 1-2 | |
| » Starters: Jean Dubuc vs George Kahler | Fifth | 1½ out |
| Tuesday, April 15 |
| » Lost to Indians (2-2), 9-0 | League Park II (1-1) | 1-3 | |
| » Starters: George Boehler vs Cy Falkenberg | Sixth | 2 out |
| Wednesday, April 16 |
| » Lost to Indians (3-2), 2-1 | League Park II (1-2) | 1-4 | Lost 2 |
| » Starters: George Mullin vs Vean Gregg | Eighth | 2½ out |
| » Major-league debuts: Ray Powell (Tigers) |
| Thursday, April 17 |
| » Defeated Browns (3-4), 4-3 | Tiger Stadium (1-0) | 2-4 | |
| » Starters: Walt Leverenz vs Marc Hall | Sixth | 2½ out |
| Friday, April 18 |
| » Lost to Browns (4-4), 3-2 | Tiger Stadium (1-1) | 2-5 | |
| » Starters: Carl Weilman vs Joe Lake | Seventh | 3 out |
| » Major-league debuts: Walt Leverenz (Browns) |
| Former Tiger Roscoe Miller dies in Corydon, IN at the age of 37. |
| Saturday, April 19 |
| » Defeated Browns (4-5), 4-0 | Tiger Stadium (2-1) | 3-5 | |
| » Starters: Mack Allison vs Jean Dubuc | Sixth | 3 out |
| » Major-league debuts: Red McKee (Tigers) |
| Sunday, April 20 |
| » Defeated Browns (4-6), 3-2 | Tiger Stadium (3-1) | 4-5 | Won 2 |
| » Starters: George Baumgardner vs George Mullin | Fifth | 2½ out |
| Monday, April 21 |
| » Defeated White Sox (5-6), 3-2 | Comiskey Park I (1-0) | 5-5 | Won 3 |
| » Starters: Al Klawitter vs Reb Russell | Fourth | 2½ out |
| Tuesday, April 22 |
| » Lost to White Sox (6-6), 3-2 | Comiskey Park I (1-1) | 5-6 | |
| » Starters: Fred House vs Jim Scott | Fifth | 3 out |
| » Major-league debuts: Frank Gibson (Tigers) |
| Wednesday, April 23 |
| » Lost to White Sox (7-6), 2-1 | Comiskey Park I (1-2) | 5-7 | Lost 2 |
| » Starters: Marc Hall vs Doc White | Fifth | 3½ out |
| Thursday, April 24 |
| » Lost to Indians (9-4), 5-3 | Tiger Stadium (3-2) | 5-8 | Lost 3 |
| » Starters: Vean Gregg vs Jean Dubuc | Sixth | 4 out |
| Friday, April 25 |
| » Lost to Indians (10-4), 3-0 | Tiger Stadium (3-3) | 5-9 | Lost 4 |
| » Starters: Fred Blanding vs George Mullin | Sixth | 5 out |
| Tuesday, April 29 |
| » Lost to White Sox (9-8), 6-5 | Tiger Stadium (3-4) | 5-10 | Lost 5 |
| » Starters: Doc White vs Marc Hall | Seventh | 6 out |
| Wednesday, April 30 |
| » Lost to White Sox (10-8), 8-3 | Tiger Stadium (3-5) | 5-11 | Lost 6 |
| » Starters: Eddie Cicotte vs Jean Dubuc | Seventh | 6 out |
| Thursday, May 1 |
| » Lost to White Sox (11-8), 8-5 | Tiger Stadium (3-6) | 5-12 | Lost 7 |
| » Starters: Reb Russell vs George Mullin | Seventh | 7 out |
| Friday, May 2 |
| » Lost to White Sox (12-8), 2-1 | Tiger Stadium (3-7) | 5-13 | Lost 8 |
| » Starters: Jim Scott vs Ed Willett | Seventh | 8 out |
| Saturday, May 3 |
| » Lost to White Sox (13-8), 6-4 | Tiger Stadium (3-8) | 5-14 | Lost 9 |
| » Starters: Joe Benz vs Marc Hall | Seventh | 9 out |
| Sunday, May 4 |
| » Defeated White Sox (13-9), 2-1 | Comiskey Park I (2-2) | 6-14 | |
| » Starters: Jean Dubuc vs Doc White | Seventh | 8½ out |
| Wednesday, May 7 |
| » Lost to Yankees (3-15), 6-0 | Tiger Stadium (3-9) | 6-15 | |
| » Starters: Ray Keating vs George Mullin | Seventh | 10 out |
| Thursday, May 8 |
| » Defeated Yankees (3-16), 3-1 | Tiger Stadium (4-9) | 7-15 | |
| » Starters: Al Schulz vs Marc Hall | Seventh | 10 out |
| Friday, May 9 |
| » Lost to Yankees (4-16), 9-0 | Tiger Stadium (4-10) | 7-16 | |
| » Starters: Jack Warhop vs Ed Willett | Seventh | 10 out |
| Saturday, May 10 |
| » Lost to Yankees (5-16), 10-9 | Tiger Stadium (4-11) | 7-17 | Lost 2 |
| » Starters: Ray Fisher vs Hooks Dauss | Seventh | 11 out |
| Sunday, May 11 |
| » Lost to Red Sox (9-14), 5-4 | Tiger Stadium (4-12) | 7-18 | Lost 3 |
| » Starters: Ray Collins vs Jean Dubuc | Seventh | 11 out |
| Monday, May 12 |
| » Defeated Red Sox (9-15), 8-7 | Tiger Stadium (5-12) | 8-18 | |
| » Starters: Dutch Leonard vs Fred House | Seventh | 11 out |
| Tuesday, May 13 |
| » Lost to Red Sox (10-15), 6-1 | Tiger Stadium (5-13) | 8-19 | |
| » Starters: Buck O'Brien vs George Mullin | Seventh | 11½ out |
| Wednesday, May 14 |
| » Defeated Red Sox (10-16), 4-1 | Tiger Stadium (6-13) | 9-19 | |
| » Starters: Hugh Bedient vs Ed Willett | Seventh | 11 out |
| Friday, May 16 |
| » Defeated Senators (15-9), 5-2 | Tiger Stadium (7-13) | 10-19 | Won 2 |
| » Starters: Tom Hughes vs Jean Dubuc | Seventh | 10½ out |
| Saturday, May 17 |
| » Lost to Senators (16-9), 5-2 | Tiger Stadium (7-14) | 10-20 | |
| » Starters: Bob Groom vs Marc Hall | Seventh | 10½ out |
| Sunday, May 18 |
| » Lost to Senators (17-9), 2-1 | Tiger Stadium (7-15) | 10-21 | Lost 2 |
| » Starters: Walter Johnson vs Carl Zamloch | Seventh | 11½ out |
| Monday, May 19 |
| » Defeated Athletics (19-8), 9-3 | Tiger Stadium (8-15) | 11-21 | |
| » Starters: Weldon Wyckoff vs Ed Willett | Seventh | 10½ out |
| Tuesday, May 20 |
| » Defeated Athletics (19-9), 8-7 | Tiger Stadium (9-15) | 12-21 | Won 2 |
| » Starters: Byron Houck vs Al Klawitter | Seventh | 9½ out |
| Thursday, May 22 |
| » Lost to Athletics (20-9), 7-0 | Tiger Stadium (9-16) | 12-22 | |
| » Starters: Eddie Plank vs Marc Hall | Seventh | 10½ out |
| Saturday, May 24 |
| » Defeated Browns (16-22), 7-4 | Sportsman's Park III (1-2) | 13-22 | |
| » Starters: Jean Dubuc vs Carl Weilman | Seventh | 10½ out |
| Sunday, May 25 |
| » Defeated Browns (16-23), 7-4 | Sportsman's Park III (2-2) | 14-22 | Won 2 |
| » Starters: Ed Willett vs Walt Leverenz | Sixth | 9½ out |
| » Defeated Browns (16-24), 8-6 | Sportsman's Park III (3-2) | 15-22 | Won 3 |
| » Starters: Joe Lake vs Earl Hamilton | Sixth | 9½ out |
| Monday, May 26 |
| » Lost to Browns (17-24), 4-3 | Sportsman's Park III (3-3) | 15-23 | |
| » Starters: Hooks Dauss vs Carl Weilman | Seventh | 10 out |
| Tuesday, May 27 |
| » Lost to Browns (18-24), 3-2 | Sportsman's Park III (3-4) | 15-24 | Lost 2 |
| » Starters: Carl Zamloch vs Roy Mitchell | Seventh | 11½ out |
| Wednesday, May 28 |
| » Defeated Browns (18-25), 6-3 | Sportsman's Park III (4-4) | 16-24 | |
| » Starters: Marc Hall vs George Baumgardner | Seventh | 11 out |
| Thursday, May 29 |
| » Lost to White Sox (22-18), 3-2 | Comiskey Park I (2-3) | 16-25 | |
| » Starters: Ed Willett vs Reb Russell | Seventh | 12 out |
| Friday, May 30 |
| » Defeated White Sox (22-19), 3-2 | Comiskey Park I (3-3) | 17-25 | |
| » Starters: Joe Lake vs Pop-boy Smith | Seventh | 13 out |
| » Lost to White Sox (23-19), 9-1 | Comiskey Park I (3-4) | 17-26 | |
| » Starters: Hooks Dauss vs Eddie Cicotte | Seventh | 13 out |
| Saturday, May 31 |
| » Lost to White Sox (24-19), 3-2 | Comiskey Park I (3-5) | 17-27 | Lost 2 |
| » Starters: Carl Zamloch vs Doc White | Seventh | 14 out |
| Sunday, June 1 |
| » Defeated White Sox (24-20), 1-0 | Comiskey Park I (4-5) | 18-27 | |
| » Starters: Marc Hall vs Jim Scott | Sixth | 13½ out |
| Tuesday, June 3 |
| » Lost to Athletics (31-10), 7-3 | Shibe Park (0-1) | 18-28 | |
| » Starters: Hooks Dauss vs Eddie Plank | Sixth | 15½ out |
| Wednesday, June 4 |
| » Lost to Athletics (32-10), 14-6 | Shibe Park (0-2) | 18-29 | Lost 2 |
| » Starters: Jean Dubuc vs Weldon Wyckoff | Sixth | 16½ out |
| Thursday, June 5 |
| » Lost to Athletics (33-10), 10-6 | Shibe Park (0-3) | 18-30 | Lost 3 |
| » Starters: Ed Willett vs Ensign Cottrell | Seventh | 17½ out |
| Friday, June 6 |
| » Lost to Athletics (34-10), 8-7 | Shibe Park (0-4) | 18-31 | Lost 4 |
| » Starters: Joe Lake vs Eddie Plank | Seventh | 18½ out |
| Saturday, June 7 |
| » Defeated Senators (25-21), 11-1 | Griffith Stadium (1-0) | 19-31 | |
| » Starters: Hooks Dauss vs Bob Groom | Sixth | 18½ out |
| Monday, June 9 |
| » Defeated Senators (25-22), 6-4 | Griffith Stadium (2-0) | 20-31 | Won 2 |
| » Starters: Ed Willett vs Tom Hughes | Sixth | 18½ out |
| Tuesday, June 10 |
| » Lost to Senators (26-22), 3-0 | Griffith Stadium (2-1) | 20-32 | |
| » Starters: Al Clauss vs Walter Johnson | Sixth | 19½ out |
| Wednesday, June 11 |
| » Defeated Senators (26-23), 11-0 | Griffith Stadium (3-1) | 21-32 | |
| » Starters: Hooks Dauss vs Joe Engel | Sixth | 18½ out |
| Thursday, June 12 |
| » Lost to Yankees (12-36), 2-1 | Polo Grounds V (0-1) | 21-33 | |
| » Starters: Joe Lake vs Al Schulz | Sixth | 19½ out |
| Friday, June 13 |
| » Lost to Yankees (13-36), 4-2 | Polo Grounds V (0-2) | 21-34 | Lost 2 |
| » Starters: Jean Dubuc vs Russ Ford | Sixth | 20½ out |
| Saturday, June 14 |
| » Defeated Yankees (13-37), 6-5 | Polo Grounds V (1-2) | 22-34 | |
| » Starters: Ed Willett vs George McConnell | Sixth | 19½ out |
| Monday, June 16 |
| » Defeated Yankees (13-38), 5-3 | Polo Grounds V (2-2) | 23-34 | Won 2 |
| » Starters: Marc Hall vs Al Schulz | Sixth | 19½ out |
| Tuesday, June 17 |
| » Lost to Red Sox (27-25), 7-4 | Fenway Park (0-1) | 23-35 | |
| » Starters: Carl Zamloch vs Earl Moseley | Sixth | 20 out |
| » Defeated Red Sox (27-26), 4-3 | Fenway Park (1-1) | 24-35 | |
| » Starters: Hooks Dauss vs Hugh Bedient | Sixth | 20 out |
| » Major-league debuts: Earl Moseley (Red Sox) |
| Wednesday, June 18 |
| » Lost to Red Sox (28-26), 7-6 | Fenway Park (1-2) | 24-36 | |
| » Starters: Ed Willett vs Ray Collins | Sixth | 20 out |
| Thursday, June 19 |
| » Lost to Red Sox (29-26), 5-4 | Fenway Park (1-3) | 24-37 | Lost 2 |
| » Starters: Jean Dubuc vs Buck O'Brien | Sixth | 21 out |
| Saturday, June 21 |
| » Lost to Indians (38-22), 7-6 | League Park II (1-3) | 24-38 | Lost 3 |
| » Starters: Hooks Dauss vs Cy Falkenberg | Sixth | 20½ out |
| Sunday, June 22 |
| » Defeated Indians (38-23), 7-6 | League Park II (2-3) | 25-38 | |
| » Starters: Ed Willett vs Cy Falkenberg | Sixth | 20½ out |
| » Lost to Indians (39-23), 2-1 | League Park II (2-4) | 25-39 | |
| » Starters: Hooks Dauss vs Vean Gregg | Sixth | 20½ out |
| Tuesday, June 24 |
| » Lost to Indians (40-23), 6-4 | Tiger Stadium (9-17) | 25-40 | Lost 2 |
| » Starters: George Kahler vs Ed Willett | Sixth | 21 out |
| » Defeated Indians (40-24), 6-5 | Tiger Stadium (10-17) | 26-40 | |
| » Starters: Fred Blanding vs Carl Zamloch | Sixth | 21 out |
| Wednesday, June 25 |
| » Defeated Indians (40-25), 4-2 | Tiger Stadium (11-17) | 27-40 | Won 2 |
| » Starters: Nick Cullop vs Jean Dubuc | Sixth | 21 out |
| Thursday, June 26 |
| » Lost to Browns (26-44), 7-5 | Tiger Stadium (11-18) | 27-41 | |
| » Starters: Walt Leverenz vs Hooks Dauss | Sixth | 22½ out |
| Friday, June 27 |
| » Lost to Browns (27-44), 8-3 | Tiger Stadium (11-19) | 27-42 | Lost 2 |
| » Starters: Carl Weilman vs Marc Hall | Sixth | 23 out |
| Saturday, June 28 |
| » Lost to Browns (28-44), 7-1 | Tiger Stadium (11-20) | 27-43 | Lost 3 |
| » Starters: Earl Hamilton vs Ed Willett | Seventh | 23 out |
| Sunday, June 29 |
| » Defeated Browns (28-45), 5-2 | Tiger Stadium (12-20) | 28-43 | |
| » Starters: Roy Mitchell vs Jean Dubuc | Sixth | 22½ out |
| » Major-league debuts: Wally Pipp (Tigers) |
| Monday, June 30 |
| » Lost to White Sox (39-32), 6-4 | Tiger Stadium (12-21) | 28-44 | |
| » Starters: Doc White vs Marc Hall | Sixth | 23½ out |
| Tuesday, July 1 |
| » Lost to White Sox (40-32), 3-2 | Tiger Stadium (12-22) | 28-45 | Lost 2 |
| » Starters: Eddie Cicotte vs Ed Willett | Sixth | 24½ out |
| Wednesday, July 2 |
| » Defeated White Sox (40-33), 7-5 | Tiger Stadium (13-22) | 29-45 | |
| » Starters: Joe Benz vs Joe Lake | Sixth | 24½ out |
| Thursday, July 3 |
| » Lost to Indians (44-29), 3-1 | League Park II (2-5) | 29-46 | |
| » Starters: Hooks Dauss vs George Kahler | Sixth | 25½ out |
| Friday, July 4 |
| » Lost to Indians (45-29), 4-2 | League Park II (2-6) | 29-47 | Lost 2 |
| » Starters: Jean Dubuc vs Fred Blanding | Seventh | 26½ out |
| » Lost to Indians (46-29), 4-2 | League Park II (2-7) | 29-48 | Lost 3 |
| » Starters: Ed Willett vs Vean Gregg | Seventh | 26½ out |
| Saturday, July 5 |
| » Defeated Browns (30-50), 7-5 | Sportsman's Park III (5-4) | 30-48 | |
| » Starters: Marc Hall vs Carl Weilman | Sixth | 26½ out |
| Sunday, July 6 |
| » Lost to Browns (31-50), 2-1 | Sportsman's Park III (5-5) | 30-49 | |
| » Starters: Joe Lake vs Earl Hamilton | Seventh | 27 out |
| Monday, July 7 |
| » Lost to Browns (32-50), 10-5 | Sportsman's Park III (5-6) | 30-50 | Lost 2 |
| » Starters: Hooks Dauss vs Roy Mitchell | Seventh | 27½ out |
| Wednesday, July 9 |
| » Defeated Senators (42-35), 5-3 | Tiger Stadium (14-22) | 31-50 | |
| » Starters: Bob Groom vs Hooks Dauss | Seventh | 28 out |
| » Lost to Senators (43-35), 9-0 | Tiger Stadium (14-23) | 31-51 | |
| » Starters: Walter Johnson vs Jean Dubuc | Seventh | 28 out |
| Thursday, July 10 |
| » Defeated Senators (43-36), 4-2 | Tiger Stadium (15-23) | 32-51 | |
| » Starters: Tom Hughes vs Marc Hall | Sixth | 27 out |
| Friday, July 11 |
| » Lost to Senators (44-36), 5-2 | Tiger Stadium (15-24) | 32-52 | |
| » Starters: Joe Boehling vs Ed Willett | Seventh | 28 out |
| Saturday, July 12 |
| » Lost to Athletics (57-20), 16-9 | Tiger Stadium (15-25) | 32-53 | Lost 2 |
| » Starters: Boardwalk Brown vs Jean Dubuc | Seventh | 29 out |
| Sunday, July 13 |
| » Defeated Athletics (57-21), 7-1 | Tiger Stadium (16-25) | 33-53 | |
| » Starters: Byron Houck vs Hooks Dauss | Sixth | 27 out |
| » Defeated Athletics (57-22), 5-4 | Tiger Stadium (17-25) | 34-53 | Won 2 |
| » Starters: Bullet Joe Bush vs Ed Willett | Sixth | 27 out |
| Monday, July 14 |
| » Defeated Athletics (57-23), 9-8 | Tiger Stadium (18-25) | 35-53 | Won 3 |
| » Starters: Chief Bender vs Marc Hall | Sixth | 26 out |
| Tuesday, July 15 |
| » Lost to Athletics (58-23), 7-0 | Tiger Stadium (18-26) | 35-54 | |
| » Starters: Eddie Plank vs Marc Hall | Seventh | 27 out |
| Wednesday, July 16 |
| » Lost to Red Sox (40-41), 7-4 | Tiger Stadium (18-27) | 35-55 | Lost 2 |
| » Starters: Ray Collins vs Ed Willett | Seventh | 27½ out |
| Friday, July 18 |
| » Defeated Red Sox (40-42), 5-1 | Tiger Stadium (19-27) | 36-55 | |
| » Starters: Joe Wood vs Hooks Dauss | Sixth | 27 out |
| Saturday, July 19 |
| » Defeated Red Sox (40-43), 3-1 | Tiger Stadium (20-27) | 37-55 | Won 2 |
| » Starters: Dutch Leonard vs Jean Dubuc | Sixth | 27 out |
| » Lost to Red Sox (41-43), 6-2 | Tiger Stadium (20-28) | 37-56 | |
| » Starters: Rube Foster vs Joe Lake | Sixth | 27 out |
| Sunday, July 20 |
| » Lost to Yankees (28-57), 10-5 | Tiger Stadium (20-29) | 37-57 | Lost 2 |
| » Starters: Jack Warhop vs Marc Hall | Sixth | 28 out |
| Monday, July 21 |
| » Defeated Yankees (28-58), 6-1 | Tiger Stadium (21-29) | 38-57 | |
| » Starters: George McConnell vs Ed Willett | Sixth | 28 out |
| Tuesday, July 22 |
| » Defeated Yankees (28-59), 2-0 | Tiger Stadium (22-29) | 39-57 | Won 2 |
| » Starters: Russ Ford vs Hooks Dauss | Sixth | 27 out |
| Friday, July 25 |
| » Lost to Athletics (65-27), 4-0 | Shibe Park (0-5) | 39-58 | |
| » Starters: Jean Dubuc vs Bob Shawkey | Sixth | 28½ out |
| Saturday, July 26 |
| » Defeated Athletics (65-28), 6-2 | Shibe Park (1-5) | 40-58 | |
| » Starters: Ed Willett vs Eddie Plank | Sixth | 27½ out |
| Tuesday, July 29 |
| » Lost to Athletics (66-28), 8-0 | Shibe Park (1-6) | 40-59 | |
| » Starters: Hooks Dauss vs Boardwalk Brown | Sixth | 28½ out |
| Thursday, July 31 |
| » Defeated Senators (55-41), 4-1 | Griffith Stadium (4-1) | 41-59 | |
| » Starters: Marc Hall vs Joe Boehling | Sixth | 28 out |
| Friday, August 1 |
| » Defeated Senators (55-42), 9-3 | Griffith Stadium (5-1) | 42-59 | Won 2 |
| » Starters: Joe Lake vs Bob Groom | Sixth | 27 out |
| Saturday, August 2 |
| » Lost to Senators (56-42), 3-2 | Griffith Stadium (5-2) | 42-60 | |
| » Starters: Hooks Dauss vs Walter Johnson | Sixth | 28 out |
| Monday, August 4 |
| » Lost to Yankees (32-63), 6-4 | Polo Grounds V (2-3) | 42-61 | Lost 2 |
| » Starters: Ed Willett vs Ray Fisher | Sixth | 29 out |
| Tuesday, August 5 |
| » Defeated Yankees (32-64), 10-5 | Polo Grounds V (3-3) | 43-61 | |
| » Starters: Jean Dubuc vs Ray Keating | Sixth | 28 out |
| Wednesday, August 6 |
| » Defeated Yankees (32-65), 2-1 | Polo Grounds V (4-3) | 44-61 | Won 2 |
| » Starters: Hooks Dauss vs Russ Ford | Sixth | 28 out |
| Thursday, August 7 |
| » Lost to Yankees (33-65), 5-1 | Polo Grounds V (4-4) | 44-62 | |
| » Starters: Joe Lake vs Al Schulz | Sixth | 29 out |
| » Major-league debuts: Doc Cook (Yankees) |
| Friday, August 8 |
| » Lost to Red Sox (50-52), 5-4 | Fenway Park (1-4) | 44-63 | Lost 2 |
| » Starters: Marc Hall vs Earl Moseley | Sixth | 29 out |
| Saturday, August 9 |
| » Defeated Red Sox (50-53), 6-3 | Fenway Park (2-4) | 45-63 | |
| » Starters: Ed Willett vs Ray Collins | Sixth | 28 out |
| Monday, August 11 |
| » Defeated Red Sox (50-54), 6-2 | Fenway Park (3-4) | 46-63 | Won 2 |
| » Starters: Hooks Dauss vs Dutch Leonard | Sixth | 28 out |
| Thursday, August 14 |
| » Defeated Senators (59-48), 5-4 | Tiger Stadium (23-29) | 47-63 | Won 3 |
| » Starters: Joe Boehling vs Jean Dubuc | Sixth | 26½ out |
| Friday, August 15 |
| » Lost to Senators (60-48), 9-7 | Tiger Stadium (23-30) | 47-64 | |
| » Starters: Walter Johnson vs Marc Hall | Sixth | 27½ out |
| Saturday, August 16 |
| » Lost to Senators (61-48), 6-1 | Tiger Stadium (23-31) | 47-65 | Lost 2 |
| » Starters: Bob Groom vs Hooks Dauss | Sixth | 27½ out |
| Sunday, August 17 |
| » Defeated Senators (61-49), 7-1 | Tiger Stadium (24-31) | 48-65 | |
| » Starters: Joe Engel vs Ed Willett | Sixth | 26½ out |
| Future Tiger Rudy York is born in Ragland, AL. |
| Monday, August 18 |
| » Defeated Athletics (73-38), 5-4 | Tiger Stadium (25-31) | 49-65 | Won 2 |
| » Starters: Eddie Plank vs Jean Dubuc | Sixth | 25½ out |
| Tuesday, August 19 |
| » Lost to Athletics (74-38), 4-3 | Tiger Stadium (25-32) | 49-66 | |
| » Starters: Bob Shawkey vs Marc Hall | Sixth | 26½ out |
| Wednesday, August 20 |
| » Lost to Athletics (75-38), 5-2 | Tiger Stadium (25-33) | 49-67 | Lost 2 |
| » Starters: Boardwalk Brown vs Hooks Dauss | Sixth | 27½ out |
| Friday, August 22 |
| » Defeated Yankees (38-72), 7-4 | Tiger Stadium (26-33) | 50-67 | |
| » Starters: Russ Ford vs Ed Willett | Sixth | 28½ out |
| » Lost to Yankees (39-72), 12-7 | Tiger Stadium (26-34) | 50-68 | |
| » Starters: Al Schulz vs Lou North | Sixth | 28½ out |
| » Major-league debuts: Lou North (Tigers) |
| Saturday, August 23 |
| » Defeated Yankees (39-73), 8-1 | Tiger Stadium (27-34) | 51-68 | |
| » Starters: Ray Fisher vs Jean Dubuc | Sixth | 28 out |
| » Lost to Yankees (40-73), 4-2 | Tiger Stadium (27-35) | 51-69 | |
| » Starters: Ray Caldwell vs Joe Lake | Sixth | 28 out |
| Sunday, August 24 |
| » Lost to Red Sox (57-58), 3-0 | Tiger Stadium (27-36) | 51-70 | Lost 2 |
| » Starters: Earl Moseley vs Hooks Dauss | Sixth | 29 out |
| Monday, August 25 |
| » Defeated Red Sox (57-59), 6-5 | Tiger Stadium (28-36) | 52-70 | |
| » Starters: Dutch Leonard vs Joe Lake | Sixth | 29 out |
| Former Tiger Red Donahue dies in Philadelphia, PA at the age of 41. |
| Tuesday, August 26 |
| » Lost to Red Sox (58-59), 7-6 | Tiger Stadium (28-37) | 52-71 | |
| » Starters: Fred Anderson vs Ralph Comstock | Sixth | 30 out |
| » Major-league debuts: Ralph Comstock (Tigers) |
| Wednesday, August 27 |
| » Major-league debuts: Rube Schauer (Giants) |
| Saturday, August 30 |
| » Defeated White Sox (65-60), 8-5 | Comiskey Park I (5-5) | 53-71 | |
| » Starters: Jean Dubuc vs Jim Scott | Sixth | 29 out |
| Sunday, August 31 |
| » Defeated White Sox (65-61), 5-4 | Comiskey Park I (6-5) | 54-71 | Won 2 |
| » Starters: Ed Willett vs Reb Russell | Sixth | 28½ out |
| Monday, September 1 |
| » Defeated Browns (48-82), 10-5 | Tiger Stadium (29-37) | 55-71 | Won 3 |
| » Starters: Walt Leverenz vs Hooks Dauss | Sixth | 28½ out |
| » Defeated Browns (48-83), 5-2 | Tiger Stadium (30-37) | 56-71 | Won 4 |
| » Starters: George Baumgardner vs Ralph Comstock | Sixth | 28½ out |
| Thursday, September 4 |
| » Defeated Indians (77-52), 4-3 | League Park II (3-7) | 57-71 | Won 5 |
| » Starters: Jean Dubuc vs Vean Gregg | Sixth | 27 out |
| Friday, September 5 |
| » Lost to Indians (78-52), 7-6 | League Park II (3-8) | 57-72 | |
| » Starters: Ed Willett vs Lefty James | Sixth | 27 out |
| Saturday, September 6 |
| » Lost to Indians (79-52), 3-1 | Tiger Stadium (30-38) | 57-73 | Lost 2 |
| » Starters: Cy Falkenberg vs Hooks Dauss | Sixth | 28 out |
| Sunday, September 7 |
| » Lost to Indians (80-52), 6-4 | Tiger Stadium (30-39) | 57-74 | Lost 3 |
| » Starters: Bill Steen vs Ralph Comstock | Sixth | 28½ out |
| Tuesday, September 9 |
| » Lost to Red Sox (66-63), 3-2 | Fenway Park (3-5) | 57-75 | Lost 4 |
| » Starters: Charlie Grover vs Earl Moseley | Sixth | 28½ out |
| Wednesday, September 10 |
| » Lost to Red Sox (67-63), 4-2 | Fenway Park (3-6) | 57-76 | Lost 5 |
| » Starters: Ed Willett vs Ray Collins | Sixth | 28½ out |
| Thursday, September 11 |
| » Defeated Red Sox (67-64), 15-2 | Fenway Park (4-6) | 58-76 | |
| » Starters: Hooks Dauss vs Hugh Bedient | Sixth | 28½ out |
| Friday, September 12 |
| » Lost to Red Sox (68-64), 18-5 | Fenway Park (4-7) | 58-77 | |
| » Starters: Ralph Comstock vs Dutch Leonard | Sixth | 29½ out |
| Saturday, September 13 |
| » Lost to Yankees (49-84), 4-3 | Polo Grounds V (4-5) | 58-78 | Lost 2 |
| » Starters: Jean Dubuc vs Al Schulz | Sixth | 29½ out |
| Monday, September 15 |
| » Defeated Yankees (49-85), 7-5 | Polo Grounds V (5-5) | 59-78 | |
| » Starters: Ed Willett vs Ray Fisher | Sixth | 29½ out |
| Tuesday, September 16 |
| » Defeated Yankees (49-86), 4-3 | Polo Grounds V (6-5) | 60-78 | Won 2 |
| » Starters: Hooks Dauss vs Ray Caldwell | Sixth | 29½ out |
| Wednesday, September 17 |
| » Defeated Senators (79-60), 5-1 | Griffith Stadium (6-2) | 61-78 | Won 3 |
| » Starters: Jean Dubuc vs Bert Gallia | Sixth | 29 out |
| » Defeated Senators (79-61), 4-2 | Griffith Stadium (7-2) | 62-78 | Won 4 |
| » Starters: Lefty Williams vs Joe Boehling | Sixth | 29 out |
| » Major-league debuts: Lefty Williams (Tigers) |
| Thursday, September 18 |
| » Lost to Senators (80-61), 6-1 | Griffith Stadium (7-3) | 62-79 | |
| » Starters: Erwin Renfer vs Bob Groom | Sixth | 29 out |
| Friday, September 19 |
| » Lost to Senators (81-61), 2-1 | Griffith Stadium (7-4) | 62-80 | Lost 2 |
| » Starters: Ralph Comstock vs Slim Love | Sixth | 29½ out |
| Saturday, September 20 |
| » Lost to Athletics (91-49), 4-2 | Shibe Park (1-7) | 62-81 | Lost 3 |
| » Starters: Ed Willett vs Byron Houck | Fifth | 30½ out |
| Monday, September 22 |
| » Lost to Athletics (92-49), 4-0 | Shibe Park (1-8) | 62-82 | Lost 4 |
| » Starters: Hooks Dauss vs Bullet Joe Bush | Sixth | 32½ out |
| » Lost to Athletics (93-49), 1-0 | Shibe Park (1-9) | 62-83 | Lost 5 |
| » Starters: Jean Dubuc vs Herb Pennock | Sixth | 32½ out |
| Tuesday, September 23 |
| » Lost to Athletics (94-49), 21-8 | Shibe Park (1-10) | 62-84 | Lost 6 |
| » Starters: Lefty Williams vs Herb Pennock | Sixth | 33½ out |
| Saturday, September 27 |
| » Defeated Indians (83-63), 7-6 | Tiger Stadium (31-39) | 63-84 | |
| » Starters: Bill Steen vs Jean Dubuc | Sixth | 31½ out |
| » Defeated Indians (83-64), 4-3 | Tiger Stadium (32-39) | 64-84 | Won 2 |
| » Starters: Nick Cullop vs Ed Willett | Sixth | 31½ out |
| Sunday, September 28 |
| » Lost to Browns (56-94), 3-1 | Tiger Stadium (32-40) | 64-85 | |
| » Starters: Curly Brown vs Lefty Williams | Sixth | 32 out |
| Monday, September 29 |
| » Major-league debuts: Wickey McAvoy (Athletics) |
| Wednesday, October 1 |
| » Lost to Indians (84-65), 8-1 | Tiger Stadium (32-41) | 64-86 | Lost 2 |
| » Starters: Vean Gregg vs Ralph Comstock | Sixth | 31 out |
| Saturday, October 4 |
| » Defeated White Sox (77-73), 7-5 | Tiger Stadium (33-41) | 65-86 | |
| » Starters: Joe Benz vs Hooks Dauss | Sixth | 30½ out |
| » Lost to White Sox (78-73), 1-0 | Tiger Stadium (33-42) | 65-87 | |
| » Starters: Reb Russell vs Lefty Williams | Sixth | 30½ out |
| Sunday, October 5 |
| » Defeated White Sox (78-74), 9-8 | Tiger Stadium (34-42) | 66-87 | |
| » Starters: Jim Scott vs Ralph Comstock | Sixth | 30 out |
| Saturday, October 18 |
| Future Tiger Roy Cullenbine is born in Nashville, TN. |
| Tuesday, October 21 |
| Future Tiger Mark Christman is born in Maplewood, MO. |
| Monday, November 24 |
| Future Tiger Walter Wilson is born in Glenn, GA. |
Game information provided by Retrosheet (www.retrosheet.org) |